System with measuring components for safe transdermal drug delivery
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-01-24
- Publication Date
- 2026-08-11
Smart Images
Figure CN122555587A_ABST
Abstract
Description
Summary of the Invention
[0001] This document discloses a cartridge for treating skin and transdermal drug delivery, comprising: a microneedle plane including one or more microneedles and configured to pretreat skin to provide treatment; one or more sensors configured to measure one or more cartridge data; and a chip configured to acquire one or more cartridge data and adjust treatment based on the one or more data.
[0002] In some embodiments, the chip is a near field communication (NFC) tag. In some embodiments, the chip is a microcontroller unit (MCU) tag. In some embodiments, the chip is an optical identification sensor.
[0003] In some embodiments, the housing also includes a cover configured to cover one or more microneedles.
[0004] In some embodiments, one or more sensors are humidity sensors, pressure sensors, temperature sensors, optical sensors, or combinations thereof. In some embodiments, one or more data are changes in skin humidity, pressure levels of the housing, changes in skin temperature, changes in skin color, or combinations thereof.
[0005] In some embodiments, one or more microneedles are arranged in an array on a microneedle plane.
[0006] In some embodiments, treatment is applied at a treatment level selected from a plurality of treatment levels. In some embodiments, the chip is configured to reduce the treatment level when one or more data points reach or exceed one or more thresholds.
[0007] In some embodiments, an applicator is disclosed herein, including a housing configured to be removably coupled to the applicator, the housing comprising: a microneedle plane including one or more microneedles and configured to pretreat skin to provide treatment; one or more sensors configured to measure one or more housing data; and a chip configured to acquire one or more housing data and adjust treatment based on the one or more data.
[0008] In some embodiments, the applicator includes a spring disposed within an interface of the applicator; and a plug configured to engage with a cartridge, wherein the spring and the plug together include a torque-push mechanism configured to engage the cartridge to the applicator and remove the cartridge from the applicator.
[0009] In some embodiments, the applicator also includes a cap configured to cover one or more microneedles.
[0010] In some embodiments, the chip is a near field communication (NFC) tag. In some embodiments, the chip is a microcontroller unit (MCU) tag. In some embodiments, the chip is an optical identification sensor.
[0011] In some embodiments, one or more sensors are humidity sensors, pressure sensors, temperature sensors, optical sensors, or combinations thereof.
[0012] This article also discloses a method for safely applying microneedling therapy to the skin, comprising: bringing the microneedle plane of the applicator into contact with the skin; pretreating the skin at a certain treatment level using one or more microneedles; measuring one or more cartridge data using one or more sensors on the cartridge; and adjusting the treatment level based on the one or more cartridge data.
[0013] In some embodiments, the method further includes: comparing each of one or more data points to one or more thresholds; and reducing the treatment level when a threshold is reached or exceeded. In some embodiments, the one or more box data points include a pressure level of the box, and the one or more thresholds include a pressure threshold. In some embodiments, the one or more box data points include skin temperature changes, and the one or more thresholds include a temperature threshold. In some embodiments, the one or more box data points include skin color changes, and the one or more thresholds include a color threshold.
[0014] This overview is intended to introduce some concepts in a simplified form, which will be further described in the detailed embodiments below. This overview is not intended to identify key features of the claimed subject matter, nor is it intended to be used as an aid in determining the scope of the claimed subject matter. Attached Figure Description
[0015] The foregoing aspects and numerous incidental advantages of the invention will become more readily apparent from the following detailed description taken in conjunction with the accompanying drawings, wherein: Figure 1A This is a perspective view of an example applicator based on this technology; Figure 1B Based on this technology Figure 1A Exploded view of the applicator; Figure 2A-2B This is a close-up view of an example applicator with a removable housing according to the present technology; Figure 3 This is a close-up view of an example applicator with a cap according to this technology; Figure 4A This is an internal cross-sectional view of an example applicator according to this technology; Figure 4B Based on this technology Figure 4A Example of an applicator chip; Figure 5 This is an example applicator used in accordance with the technology; Figure 6 This is an exemplary method for adjusting treatment using a microneedle applicator according to the present technology; Figure 7 This is another exemplary method of adjusting treatment using a microneedle applicator according to the present technology. Detailed Implementation
[0016] Microneedling is a cosmetic procedure that uses tiny, sterilized tips or needles to promote collagen production. It can help smooth, firm, and condition the skin, and improve the appearance of scars, acne, pores, and wrinkles. This document discloses applicators, systems, and methods for applying microneedling treatments (or therapies) to the skin. In some embodiments, the applicator includes a housing with a microneedle plane comprising one or more microneedles. In some embodiments, the housing also includes a chip for acquiring one or more data points from the housing's sensor system. The chip can use the one or more data points to adjust the treatment provided by the microneedles, including but not limited to reducing treatment intensity, increasing treatment intensity, initiating treatment, or stopping treatment.
[0017] In some embodiments, the sensor system includes an optical sensor, a humidity sensor, a temperature sensor, a pressure sensor, or a combination thereof. In some embodiments, the chip and / or an external device communicatively coupled to the chip includes one or more thresholds that can be used to determine when the treatment level should be reduced, increased, stopped, or started. In some embodiments, one or more thresholds include a color threshold (i.e., the color of the user's skin), a pressure threshold, a temperature threshold, a humidity threshold, a timer, or a combination thereof.
[0018] Figure 1A This is a perspective view of an example applicator 100 according to the present technology. In some embodiments, the applicator 100 includes a body 105, an actuator 115, an electrical port 107, and a button 110. In some embodiments, the applicator also includes an interface 120 configured to be coupled to a removable housing 125. In some embodiments, the housing 125 is removably coupled to the applicator 100. In this way, the housing 125 can be removed for cleaning or can be replaced to ensure that the housing 125 is hygienic.
[0019] In some embodiments, the body 120 is substantially cylindrical, but the body 120 can adopt any forming factor. In some embodiments, the length of the body 120 is greater than its width to allow a user to hold the body 120 as if holding a writing instrument. In some embodiments, the body 120 has a biomimetic shape, such as... Figure 1AAs shown. In some embodiments, the body 120 has a first end and a second end, the first end including an electrical port 107, and the second end being configured to connect to the removable housing 120.
[0020] In some embodiments, the electrical port 107 is electrically connected to a battery located inside the applicator 100 (such as...). Figure 1B (As shown and described). In some embodiments, electrical port 107 is configured to facilitate an electrical connection between the battery and a charging device or receptacle. In some embodiments, this can be facilitated by a cable or wire. In some embodiments, electrical port 107 powers the applicator 100. In some embodiments, electrical port 107 can charge the battery of the applicator 100, and the device can operate even when not connected to a receptacle or charging device.
[0021] In some embodiments, the applicator 100 includes a button 110. In some embodiments, the button 110 is configured to turn the applicator 100 on and / or off. In some embodiments, the button 110 can be used to facilitate interaction with another device (e.g., a smart device such as...) Figure 7 The wireless connection (such as Bluetooth™, Wi-Fi, or Zigbee) shown and described herein. In some embodiments, button 110 can start or stop treatment, as described herein.
[0022] In some embodiments, actuator 112 can start or stop treatment (also referred to herein as microneedling therapy or microneedling treatment), as described herein. In some embodiments, actuator 112 can increase or decrease treatment intensity. In some embodiments, actuator 112 can be a button, a touch-sensitive capacitive button, a switch, etc.
[0023] During operation, the applicator 100 is charged or powered via the electrical port 107. In some embodiments, the applicator 100 can be turned on by pressing or actuating the button 110. In some embodiments, the user can insert a microneedle plane (e.g., microneedle plane 130, such as...) Figure 1B The applicator 100 (as shown) is placed on the user's skin. In some embodiments, the user may then press or otherwise activate the actuator 112 to initiate microneedling treatment as the user moves the applicator 100 across their skin. In some embodiments, the microneedle plane includes one or more microneedles (such as...) Figure 6 (As shown). As the user moves the applicator 100 over their skin, one or more microneedles pre-treat the user's skin to provide microneedling treatment. As used herein, the term "pre-treatment" means penetrating, peeling, or otherwise disrupting the skin barrier.
[0024] Figure 1B Based on this technology Figure 1AAn exploded view of the applicator 100. As described above, in some embodiments, the applicator 100 includes an electrical port 107, a button 110, a body 105, and an actuator 115. In some embodiments, the applicator 100 also includes a battery 121.
[0025] In some embodiments, battery 121 is a rechargeable battery, capacitor, etc. In some embodiments, battery 121 is charged via a wired connection through electrical port 107. Battery 121 can power applicator 100.
[0026] In some embodiments, the housing further includes an interface 120 configured to engage with a removable housing 125. In some embodiments, the interface 120 receives a spring 140, a plug 123, and a pin 127. In some embodiments, the applicator 100 includes a removable housing 125. In some embodiments, the housing 125 receives a secondary spring 129. In some embodiments, the housing includes a microneedle plane 130. In some embodiments, the housing 125 contains a secondary spring and a pin 127. In some embodiments, the spring 140 and the secondary spring 129 cooperate to remove the housing 125 from the applicator 100 and / or engage the housing 125 with the applicator 100, such as... Figures 2A to 2B As shown and described in more detail below. In some embodiments, the housing 125 is coupled to a microneedle plane 130 comprising one or more microneedles (e.g., Figure 6 (As shown). In some embodiments, plug 123 is configured to engage with housing 125. In some embodiments, spring 140 and plug 123 together include a torque-push mechanism configured to engage housing 125 with applicator 100 and remove housing 125 from applicator 100. In operation, when housing 125 is pushed toward plug 123, secondary spring 129 is compressed. Simultaneously, spring 140 is compressed and allows housing 125 to engage and / or interlock with plug 123 to retain housing 125 in interface 120.
[0027] Figures 2A to 2B This is a close-up view of an example applicator 100 with a removable housing 125 according to the present technology. In some embodiments, the applicator 100 includes an interface 120 configured to engage with the housing 125. In some embodiments, the housing 125 is configured to engage with the interface 120 via a "torsion locking mechanism," which may include a spring (e.g., spring 140) and a plug (e.g., plug 123). In operation, a user presses down on the housing 125 and twists the housing 125 to release it from the interface 120. To engage the housing 125 with the interface 120, the user presses the housing 125 into the interface 120 and twists the housing 125. In such embodiments, the housing 125 interlocks with the plug (e.g., plug 123) to retain the housing 125.
[0028] In some embodiments, the microneedle plane 130 includes one or more microneedles 175A, 175B, 175C…175N. In some embodiments, the one or more microneedles 175A, 175B, 175C…175N are arranged in an array. In some embodiments, the one or more microneedles 175A, 175B, 175C…175N are configured to penetrate the skin to a depth of 3 mm. In some embodiments, the one or more microneedles 175A, 175B, 175C…175N are configured to penetrate the skin to a depth of 10 μm. In some embodiments, the one or more microneedles 175A, 175B, 175C…175N are configured to ablate the skin but not penetrate it.
[0029] Figure 3 This is a close-up view of an example applicator 100 with a cap 135 according to the present technology. In some embodiments, the applicator 100 includes a cap 135. In some embodiments, the cap 135 is transparent or otherwise clear. In such embodiments, the cap 135 is configured to allow a user to see the microneedle plane 130 through the cap 135. In other embodiments, the cap 135 is opaque. In some embodiments, the cap 135 is cylindrical, but the cap 135 can take any shape or forming factor. In some embodiments, the cap 135 is plastic, glass, metal, etc. In some embodiments, the cap is configured to cover one or more microneedles (e.g., on the microneedle plane 130) on the microneedle plane 130. Figures 2A to 2B (As shown in the diagram). This prevents one or more microneedles from being bent, damaged, and / or contaminated. In some embodiments, the cap keeps the microneedles on the microneedle plane 130 clean and hygienic. In some embodiments, the cap 135 is also replaceable. During operation, the user can remove the cap 135 from the housing 123 before applying microneedling treatment to their skin.
[0030] Figure 4A This is an internal cross-sectional view of an example applicator 100 according to the present technology. In some embodiments, the applicator 100 includes a housing 125 having a microneedle plane 130. In some embodiments, the housing 125 houses a secondary spring 129 and a pin 127. In some embodiments, the housing 125 is removably coupled to an interface 120 of the applicator 100. In some embodiments, the interface 120 houses a spring 140 and a plug 123.
[0031] In some embodiments, the applicator 100 further includes a chip 145. In some embodiments, the chip 145 is configured to acquire one or more cartridge data and adjust the treatment based on the one or more data. In some embodiments, the applicator 100 further includes one or more sensors, such as... Figure 5As shown. In some embodiments, each of one or more sensors is configured to transmit cartridge data to chip 145, as described herein. In some embodiments, the sensor system includes at least a humidity sensor, a pressure sensor, or an optical sensor. In some embodiments, the optical sensor is a camera. In some embodiments, chip 145 is configured to receive one or more cartridge data from one or more sensors and compare the one or more cartridge data to one or more thresholds. If one or more cartridge data reaches or exceeds one or more thresholds, the chip instructs the applicator to reduce the treatment intensity. In some embodiments, the treatment (also referred to herein as microneedling treatment or microneedling therapy) may be provided at multiple levels. In some embodiments, one or more cartridge data determine at which of the multiple levels the treatment is applied.
[0032] Figure 4B Based on this technology Figure 4A The example applicator 100 includes a chip 145. In some embodiments, chip 145 is a near-field communication (NFC) tag. In some embodiments, chip 145 is a microcontroller unit (MCU) tag. In some embodiments, chip 145 is an optical sensor system. In some embodiments, the optical sensor system is configured to encrypt one or more pieces of data. In some embodiments, chip 145 can also communicate with an external device, such as a smart device. In some embodiments, chip 145 transmits one or more pieces of data to an external device. In some embodiments, chip 145 can instruct the applicator to adjust the treatment being applied, including but not limited to increasing or decreasing the intensity of treatment, stopping treatment, or starting treatment.
[0033] Figure 5 This is an example applicator 100 used according to the present technology. In some embodiments, housing 125 includes a sensor system. In some embodiments, the sensor system includes at least a pressure sensor 160, a humidity sensor 150, or a temperature sensor 155. In some embodiments, the sensor system includes a pressure sensor 160, a humidity sensor 150, a temperature sensor 155, or a combination thereof. In some embodiments, one or more sensors include a timer 180. In some embodiments, timer 180 transmits time data to a chip (e.g., chip 145). In some embodiments, the time data is the time elapsed since the applicator was turned on. In some embodiments, the time data is the time elapsed since the first microneedle treatment was applied. In such embodiments, the timer may be triggered, for example, by a pressure sensor 160 that detects pressure. In some embodiments, the treatment level is reduced after a period of time. In some embodiments, treatment is stopped after a period of time.
[0034] During operation, the user can move the cartridge 125 over the user's skin S as indicated by the arrow. In some embodiments, the sensor system is configured to acquire and monitor data such as the pressure the user is applying to the cartridge, the temperature of the user's skin, and / or the humidity of the user's skin. In some embodiments, a humidity sensor 150 and a thermal sensor 155 (and / or a thermocouple 165) measure the humidity and temperature of the skin for cyclical control of the microneedling therapy performance. For example, if the humidity sensor detects high humidity on the user's skin and / or the temperature sensor detects an increase in the temperature of the user's skin, the applicator 100 or an external device (e.g., Figure 7 The smart device 200 can reduce the intensity of microneedling therapy or even stop it. In some embodiments, a combination of the humidity sensor 150 and the thermal sensor (and / or thermocouple 165) is used to measure the user's transepidermal water loss (TEWL).
[0035] In some embodiments, the applicator 100 (or smart device, such as smart device 200) has a pressure threshold. In some embodiments, if the pressure measured by pressure sensor 160 exceeds the pressure threshold, the applicator 100 or an external device alerts the user to reduce the pressure. In some embodiments, microneedling therapy is stopped when the pressure exceeds the pressure threshold. A chip (e.g., chip 145) can acquire one or more cartridge data from humidity sensor 150 and / or temperature sensor 155 and compare that data with temperature and / or humidity thresholds. In some embodiments, treatment is reduced when the temperature and / or humidity reaches or exceeds the temperature and / or humidity thresholds. In this way, the applicator 100 can prevent the user from harming themselves by applying microneedling therapy at increased frequency and / or exceeding the pressure, temperature, and / or humidity thresholds.
[0036] Figure 6 This is an exemplary method 600 for regulating treatment using a microneedle applicator according to the present technology. In some embodiments, method 600 is performed by a housing and / or applicator as described herein or otherwise. In some embodiments, method 600 is performed by a housing (e.g., housing 125) having a microneedle plane (e.g., microneedle plane 130). In some embodiments, the microneedle plane includes one or more microneedles (e.g., one or more microneedles 175A, 175B, 175C…175N). In some embodiments, the housing includes one or more sensors, such as a humidity sensor, a temperature sensor, a pressure sensor, etc., as described herein. In some embodiments, the housing also includes a chip (e.g., chip 145) configured to acquire one or more housing data from one or more sensors.
[0037] In box 605, the skin is brought into contact with the microneedle plane of the applicator. In some embodiments, a pressure sensor (which may be part of a sensor system) detects the pressure being applied to the skin. In some embodiments, the pressure data is transmitted to the applicator's chip.
[0038] In box 610, the skin is pretreated using one or more microneedles of an applicator. In some embodiments, the skin is penetrated to a depth not exceeding 5.0 mm. In some embodiments, penetrating the skin with one or more microneedles is considered "microneedling therapy (or treatment)". In some embodiments, ablating without penetrating the skin is considered "microneedling therapy (or treatment)".
[0039] In box 615, a sensor system (or one or more sensors) on the housing measures one or more housing data. In some embodiments, the one or more sensors include a temperature sensor, a pressure sensor, a humidity sensor, an optical sensor, and combinations thereof. In some embodiments, data from each sensor is acquired by a chip. In some embodiments, the one or more housing data are changes in skin humidity, pressure levels in the housing, changes in skin temperature, changes in skin color, or combinations thereof.
[0040] In box 620, the chip adjusts the treatment level of the therapy based on one or more cartridge data. In some embodiments, the one or more cartridge data include pressure data, temperature data, optical data, and / or humidity data. Those skilled in the art will understand that many types of sensors can be incorporated into the cartridge for adjusting the treatment level. In some embodiments, a treatment level is selected from a plurality of treatment levels to be applied. In some embodiments, the chip is configured to reduce the treatment level when one or more cartridge data reaches or exceeds one or more thresholds, such as... Figure 7 As explained in the document.
[0041] Figure 7 This is another exemplary method of modulating treatment using a microneedle applicator according to the present technology. In some embodiments, method 700 is performed by the housing and / or applicator described herein or otherwise. In some embodiments, method 700 is performed by a housing (e.g., housing 125) having a microneedle plane (e.g., microneedle plane 130). In some embodiments, the microneedle plane includes one or more microneedles (e.g., one or more microneedles 175A, 175B, 175C…175N). In some embodiments, the housing includes one or more sensors, such as a humidity sensor, a temperature sensor, a pressure sensor, etc., as described herein. In some embodiments, the housing also includes a chip (e.g., chip 145) configured to acquire one or more housing data from one or more sensors.
[0042] In box 705, one or more cartridge data are compared to one or more thresholds. In some embodiments, the one or more thresholds include a pressure threshold, a temperature threshold, a humidity sensor threshold, a color threshold, or a combination thereof. In some embodiments, the one or more sensors include a timer. In some embodiments, the one or more thresholds include a time threshold. In some embodiments, there is a threshold associated with each of the one or more sensors on the cartridge and / or applicator.
[0043] In decision box 710, it is determined whether a threshold among one or more thresholds has been reached or exceeded. In some embodiments, if one of the one or more thresholds is reached, the method proceeds to box 715A. In some embodiments, for the method to proceed to box 715A, a majority of the one or more thresholds are reached or exceeded. In some embodiments, some of the one or more thresholds are weighted, i.e., some thresholds are more likely to cause one or more thresholds to be determined to have been reached or exceeded. For example, in some embodiments, a pressure threshold may be weighted higher than a color threshold. Therefore, if a pressure threshold is reached or exceeded, the method proceeds to box 715A. In the same example, if a color threshold is reached or exceeded, the method may alternatively proceed to box 715B. Those skilled in the art will understand that thresholds can be weighted in any manner. In some embodiments, such as when a timer is included in the cartridge and / or applicator, it may be determined that one or more thresholds have been reached after a certain period of time (e.g., 1 minute, 5 minutes, 15 minutes, etc.).
[0044] In block 715A, the treatment level is reduced when one or more thresholds are reached or exceeded. In some embodiments, microneedling therapy is applied at multiple treatment levels. In some embodiments, the treatment level corresponds to a vibration level, the number of penetrations per millisecond by one or more microneedles, the penetration depth of one or more needles, or a combination thereof. For example, in some embodiments, a higher treatment level is a deeper penetration depth of one or more microneedles, while a lower treatment level is a shallower penetration depth. Similarly, in another example, a higher treatment level is a higher number of penetrations per millisecond, while a lower treatment level is a lower number of penetrations per millisecond. This also applies when the treatment does not involve penetration. For example, in some embodiments, the treatment level may be an ablative level. In some embodiments, the lowest of the multiple treatment levels is to shut down microneedling therapy. In some embodiments, such as when the applicator includes a timer, the microneedling therapy level may be reduced to a minimum level to stop the microneedling therapy. In some embodiments, the applicator automatically adjusts the treatment level. In some embodiments, the applicator alerts the user to adjust the treatment level with an actuator (e.g., actuator 115). In some embodiments, the alert is a visual, audio, tactile, or combined type of alert.
[0045] Returning to decision box 710, if one or more thresholds are not reached, method 700 proceeds to box 715B. In some embodiments, even if one threshold is reached, it can be determined that one or more thresholds are not reached, for example, when thresholds are weighted. In other embodiments, if one of the one or more thresholds is reached, the method proceeds to box 715A.
[0046] In box 715B, the treatment level is maintained. The treatment level may be maintained until one or more of the thresholds are reached or exceeded. In some embodiments, the user closes the applicator before one or more thresholds are reached.
[0047] It should be understood that methods 600 and 700 should be interpreted as representative only. In some embodiments, the process blocks of methods 600 and 700 may be executed simultaneously, sequentially, in different orders, or even omitted without departing from the scope of this disclosure.
[0048] This application may refer to quantities and figures. Unless otherwise stated, such quantities and figures should not be considered limiting, but rather represent possible quantities and figures associated with this application. Furthermore, in this respect, the application may use the term "multiple" to refer to quantities and figures. In this respect, the term "multiple" means any quantity more than one, such as two, three, four, five, etc. The terms "about," "approximately," "close to," etc., mean ±5% of the stated numerical value. For the purposes of this disclosure, the phrase "at least one of A, B, and C" means, for example, (A), (B), (C), (A and B), (A and C), (B and C), or (A, B, and C), including all further possible permutations when listing more than three elements.
[0049] The embodiments disclosed herein may utilize circuitry to implement the techniques and methods described herein, operatively connect two or more components, generate information, determine operating conditions, control appliances, devices, or methods, etc. Any type of circuitry may be used. In the embodiments, the circuitry includes, but is not limited to, one or more computing devices, such as processors (e.g., microprocessors), central processing units (CPUs), digital signal processors (DSPs), application-specific integrated circuits (ASICs), field-programmable gate arrays (FPGAs), etc., or any combination thereof, and may include discrete digital, analog circuit elements or electronic devices, or combinations thereof.
[0050] The embodiments include one or more data stores, such as stored instructions or data. Non-limiting examples of one or more data stores include transient memory (e.g., random access memory (RAM), dynamic random access memory (DRAM), etc.), non-transitory memory (e.g., read-only memory (ROM), electrically erasable programmable read-only memory (EEPROM), optical disc read-only memory (CD-ROM), etc.), persistent memory, etc. Further non-limiting examples of one or more data stores include erasable programmable read-only memory (EPROM), flash memory, etc. One or more data stores may be connected to one or more computing devices, for example, via one or more instruction, data, or power buses.
[0051] In embodiments, the circuitry includes a computer-readable medium drive or memory slot configured to receive a signal-bearing medium (e.g., a computer-readable storage medium, a computer-readable recording medium, etc.). In embodiments, a program for causing the system to perform any of the disclosed methods may be stored on, for example, a computer-readable recording medium (CRMM), a signal-bearing medium, etc. Non-limiting examples of signal-bearing media include recordable media such as flash memory, magnetic tape, floppy disk, hard disk drive, optical disc (CD), digital video disc (DVD), Blu-ray disc, digital magnetic tape, computer memory, etc., and transmission media such as digital and / or analog communication media (e.g., fiber optic cables, waveguides, wired communication links, wireless communication links (e.g., transmitters, receivers, transceivers, transmitting logic, receiving logic, etc.)). Further non-limiting examples of signal-carrying media include, but are not limited to, DVD-ROM, DVD-RAM, DVD+RW, DVD-RW, DVD-R, DVD+R, CD-ROM, Super Audio CD, CD-R, CD+R, CD+RW, CD-RW, Video Disc, Super Video Disc, Flash Memory, Magnetic Tape, Magneto-Optical Disc, MiniDISC, Non-Temporary Storage Card, EEPROM, Optical Disc, Optical Storage, RAM, ROM, System Memory, Web Server, etc.
[0052] The detailed description set forth above in conjunction with the accompanying drawings (where like reference numerals refer to like elements) is intended as a description of various embodiments of the present disclosure and not as representation of only those embodiments. Each embodiment described in this disclosure is provided by way of example or illustration only and should not be construed as superior to or having an advantage over other embodiments. The illustrative examples provided herein are not intended to be exhaustive or to limit the present disclosure to the precise forms disclosed. Similarly, any step described herein may be interchanged with other steps or combinations of steps to achieve the same or substantially similar results. Generally, the embodiments disclosed herein are non-limiting, and the inventors believe that other embodiments within the scope of this disclosure may include the structures and functions of several specific embodiments shown in the drawings and described in the specification.
[0053] In the foregoing description, specific details have been set forth to provide a thorough understanding of exemplary embodiments of the present disclosure. However, it will be apparent to those skilled in the art that the embodiments disclosed herein can be practiced without showing all the specific details. In some instances, well-known process steps have not been described in detail in order to unnecessarily obscure various aspects of the present disclosure. Furthermore, it will be understood that embodiments of the present disclosure may employ any combination of the features described herein.
[0054] This application may include references to directions, such as “vertical,” “horizontal,” “front,” “back,” “left,” “right,” “top,” and “bottom.” These references, as well as other similar references in this application, are intended to aid in the description and understanding of particular embodiments (e.g., when such embodiments are positioned for use) and are not intended to limit this disclosure to these directions or locations.
[0055] This application may also reference quantities and figures. Unless otherwise stated, such quantities and figures should not be considered limiting, but rather exemplary descriptions of possible quantities or figures in connection with this application. Furthermore, in this regard, the term "multiple" may be used to refer to quantities or figures. In this respect, the term "multiple" means any quantity greater than one, such as two, three, four, five, etc. The terms "about," "approximately," etc., mean ±5% of the stated numerical value. The term "based on" means "at least partially based on."
[0056] The principles, representative embodiments, and modes of operation of this disclosure have been described above. However, the aspects of this disclosure intended for protection should not be construed as limited to the specific embodiments disclosed. Furthermore, the embodiments described herein should be considered illustrative rather than restrictive. It will be understood that variations and modifications can be made by those skilled in the art, and equivalents can be employed without departing from the spirit of this disclosure. Therefore, it is explicit that all such variations, modifications, and equivalents fall within the spirit and scope of the claimed disclosure.
[0057] Although illustrative embodiments have been illustrated and described, it will be understood that various changes may be made therein without departing from the spirit and scope of the invention.
Claims
1. A box for treating skin, comprising: A microneedle plane, comprising one or more microneedles, is configured to pretreat the skin to provide treatment; One or more sensors configured to measure one or more housing data; as well as A chip configured to acquire data from the one or more housings and adjust the treatment based on the one or more data.
2. The cartridge of claim 1, wherein, The chip is a Near Field Communication (NFC) tag.
3. The cartridge of claim 1, wherein, The chip is a microcontroller unit (MCU) tag or optical identification sensor.
4. The cartridge of any one of claims 1 to 3, wherein, The housing also includes a lid configured to cover the one or more microneedles.
5. The cartridge of any one of claims 1 to 4, wherein, The one or more sensors are humidity sensors, pressure sensors, temperature sensors, optical sensors, or combinations thereof.
6. The box body according to any one of claims 1 to 5, wherein, The one or more box data are changes in skin humidity, pressure levels of the box, changes in skin temperature, changes in skin color, or combinations thereof.
7. The box body according to any one of claims 1 to 6, wherein, The one or more microneedles are arranged in an array on the microneedle plane.
8. The box body according to any one of claims 1 to 7, wherein, The treatment is applied at a treatment level selected from multiple treatment levels.
9. The box body according to any one of claims 1 to 8, wherein, The chip is configured to reduce the treatment level when the data from one or more housings reaches or exceeds one or more thresholds.
10. An applicator comprising: A housing configured to be removably attached to the applicator, the housing comprising: A microneedle plane, comprising one or more microneedles, is configured to pretreat the skin to provide treatment; One or more sensors are configured to measure one or more housing data; and A chip configured to acquire data from the one or more cartridges and adjust the treatment based on the one or more cartridge data.
11. The applicator according to claim 10, wherein, The applicator includes a spring disposed inside the interface of the applicator; as well as A plug, configured to attach to the housing. The spring and the plug together include a torque-push mechanism configured to connect the cartridge to the applicator and remove the cartridge from the applicator.
12. The applicator according to claim 10 or 11, wherein, The applicator also includes a cap configured to cover the one or more microneedles.
13. The applicator according to any one of claims 10 to 12, wherein, The chip is a Near Field Communication (NFC) tag.
14. The applicator according to any one of claims 10 to 12, wherein, The chip is labeled as a microcontroller unit (MCU).
15. The applicator according to any one of claims 10 to 14, wherein, The one or more sensors are humidity sensors, pressure sensors, temperature sensors, optical sensors, or combinations thereof.
16. A method for safely applying microneedling therapy to the skin, comprising: Make the microneedle plane of the applicator contact the skin; The skin is pretreated at a certain therapeutic level using one or more microneedles; One or more box data are measured using one or more sensors on the box. as well as The treatment level is adjusted based on the data from one or more of the boxes.
17. The method according to claim 16, wherein, The method further includes: Each of the one or more box data is compared with one or more thresholds; and When the threshold is reached or exceeded, the treatment level is reduced.
18. The method according to claim 16 or 17, wherein, The one or more housing data includes the pressure level of the housing; and The one or more thresholds include pressure thresholds.
19. The method according to any one of claims 16 to 18, wherein, The one or more box data includes the temperature changes of the skin; and The one or more thresholds include temperature thresholds.
20. The method according to any one of claims 16 to 19, wherein, The one or more box data includes the skin's color changes; and The one or more thresholds include color thresholds.