Negative pressure dressing based on multi-electrode alternating pulse electric field

Abstract

This invention discloses a negative pressure dressing based on a multi-electrode alternating pulsed electric field, comprising a dressing body, a controller, and multiple electrodes. Each electrode is located at the bottom of the dressing body and is grouped in pairs to correspond to different areas of the wound. The controller is connected to each electrode and periodically switches the current direction. The controller selectively controls the direction and magnitude of the current output to each group of electrodes to form different alternating pulsed electric fields in different areas of the wound. It has the advantages of strong dynamic adjustment and improved treatment efficacy.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a negative pressure dressing based on a multi-electrode alternating pulsed electric field. Background Technology

[0002] Skin and soft tissue injuries are among the most common types of trauma in clinical practice, and the treatment of chronic, refractory wounds remains a significant challenge. Negative pressure wound therapy (NPWT) has been widely used in the treatment of chronic wounds, effectively draining exudate, reducing tissue edema, and promoting granulation tissue growth. Research indicates that bioelectrical signals play a crucial role in tissue repair. After skin injury, an endogenous electric field ("damage current") is spontaneously generated, which can directionally guide epithelial cells, fibroblasts, and other cells to migrate towards the wound center and promote angiogenesis and nerve regeneration. Based on this, existing technologies have developed negative pressure electric field dressings with external electric fields. By applying stable electrical stimulation to the wound, these dressings simulate and enhance the biological effects of the endogenous electric field. However, existing negative pressure electric field dressings have the following technical limitations: First, the electric field mode is singular and lacks dynamic adjustment capability. Existing technologies mostly use direct current electric fields with constant direction and intensity. This static stimulation mode differs significantly from the complex and dynamic physiological electrical environment within the human body. Long-term unidirectional direct current electric field stimulation can lead to adaptive responses in cells, gradually reducing the efficiency of electrotactic migration; at the same time, a continuous unidirectional electric field may cause excessive orientation of newly formed collagen fibers, affecting the structural regularity and mechanical strength of newly formed tissues, and increasing the risk of scar hyperplasia.

[0003] Second, the fixed electrode layout cannot adapt to irregular wounds. Existing technologies typically use a set of positive and negative electrodes in fixed positions to create a unidirectional electric field. When the wound shape is irregular (such as star-shaped, arc-shaped, or multi-lobed) or the wound is large, the unidirectional electric field can only guide cells in a certain area of ​​the wound to migrate towards the center, while cells in other areas may be subjected to electric field forces that deviate from the center or even in the opposite direction, resulting in uneven treatment effects and even inhibiting the healing of some areas.

[0004] Third, there is a lack of ability to independently regulate different areas of the wound. Wounds in different areas may be at different stages of healing (e.g., one side has entered the proliferative phase, while the other is still in the inflammatory phase), requiring different electric field parameters. Current technology cannot apply differentiated electric field stimulation to different areas of the wound, making precise treatment difficult. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to overcome the shortcomings of the prior art and provide a negative pressure dressing based on a multi-electrode alternating pulse electric field that can perform zoned personalized treatment for irregular wounds.

[0006] To solve the above-mentioned technical problems, the present invention adopts the following technical solution: A negative pressure dressing based on a multi-electrode alternating pulse electric field includes a dressing body, a controller, and multiple electrodes. Each electrode is located at the bottom of the dressing body and is grouped in pairs to correspond to different areas of the wound. The controller is connected to each electrode and periodically switches the direction of the current. The controller selectively controls the direction and magnitude of the current output to each group of electrodes to form different alternating pulse electric fields in different areas of the wound.

[0007] As a further improvement to the above technical solution: The negative pressure dressing also includes multiple biosensors, each of which is used to collect environmental parameters of different areas of the wound. The controller determines the healing stage of each area of ​​the wound based on the environmental parameters in order to control the alternating pulse electric field of each area of ​​the wound.

[0008] The controller is configured to be in at least one of the following modes: synchronous mode: outputting current to all electrodes simultaneously; independent mode: outputting current to all electrodes simultaneously and controlling the direction and magnitude of the current separately; time-sharing mode: outputting current to each group of electrodes sequentially.

[0009] The controller includes a storage module and a control unit. The storage module has preset treatment modes corresponding to the wound healing stage. The treatment modes include: inflammation stage mode: high frequency, high current; proliferation stage mode: medium frequency, medium current; remodeling stage mode: low frequency, low current. The control unit calls up the treatment mode according to the wound healing stage.

[0010] The top of the dressing body is covered with a flexible sealing film for sealing and fixing the dressing body to the wound.

[0011] The dressing body includes an absorbent sponge, a polyurethane sponge, and a gel layer arranged in sequence, with each electrode disposed at the bottom of the gel layer.

[0012] The negative pressure dressing also includes a negative pressure component, which includes a negative pressure suction cup and a negative pressure drainage tube. The negative pressure suction cup is placed on a flexible sealing membrane and communicates with the dressing body. One end of the negative pressure drainage tube is connected to the negative pressure suction cup, and the other end is connected to an external negative pressure device through a controller.

[0013] The negative pressure drainage tube is provided with a negative pressure interface at its end for connection to the controller.

[0014] The controller is connected to each electrode via wires, and the flexible sealing membrane is provided with conduits for placing the wires.

[0015] The controller is equipped with a first switch for controlling the alternating pulse electric field and a second switch for controlling the negative voltage. The controller is also equipped with a display screen for displaying various parameters.

[0016] Compared with the prior art, the advantages of the present invention are as follows: This invention uses multiple electrodes in multiple groups corresponding to different areas of the wound, which can apply different electric field directions and intensities to each area to achieve precise treatment of irregular wounds. By periodically switching the electric field direction through a controller, the adaptation of cells to a single electric field is avoided, which greatly improves the treatment effect. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall structure of the negative pressure dressing of the present invention.

[0018] Figure 2 This is a schematic diagram of the dressing body structure of the present invention.

[0019] Figure 3 This is a schematic diagram of the controller structure of the present invention.

[0020] Figure 4 This is a schematic diagram of the electrode arrangement in Embodiment 1 of the present invention.

[0021] Figure 5 This is a schematic diagram of the electrode arrangement in Embodiment 2 of the present invention.

[0022] The labels in the diagram represent: 1. Dressing body; 11. Absorbent sponge; 12. Polyurethane sponge; 13. Gel layer; 2. Controller; 21. First switch; 22. Second switch; 23. Display screen; 3. Electrode; 4. Flexible sealing membrane; 5. Negative pressure assembly; 51. Negative pressure suction cup; 52. Negative pressure drainage tube; 521. Negative pressure interface; 6. Wire; 7. Conduit. Detailed Implementation

[0023] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0024] Example 1: like Figures 1 to 4 As shown, the first embodiment of the negative pressure dressing based on a multi-electrode alternating pulsed electric field of the present invention includes a dressing body 1, a controller 2, and four electrodes 3. Each electrode 3 is located at the bottom of the dressing body 1 and is grouped in pairs to correspond to different areas of the wound. The controller 2 is connected to each electrode 3 and periodically switches the current direction. The controller 2 selectively controls the direction and magnitude of the current output to each group of electrodes 3 to form different alternating pulsed electric fields in different areas of the wound. The present invention uses four electrodes in two groups corresponding to two areas of the wound, which can apply different electric field directions and intensities to each area, achieving precise treatment of irregular wounds. By periodically switching the electric field direction through the controller 2, the adaptation of cells to a single electric field is avoided, greatly improving the treatment effect.

[0025] In this embodiment, the negative pressure dressing also includes multiple biosensors. Each biosensor is used to collect environmental parameters of different areas of the wound. The controller 2 determines the healing stage of each area of ​​the wound based on the environmental parameters, thereby controlling the alternating pulsed electric field of each area of ​​the wound. In this structure, the biosensors provide real-time feedback on the wound microenvironment, such as pH, temperature, and impedance. The controller 2 automatically identifies the healing stage of each area and adjusts the electric field parameters to achieve dynamic optimization of the treatment plan.

[0026] In this embodiment, the controller 2 is configured in at least one of the following modes: synchronous mode: simultaneously outputting current to all electrodes 3; independent mode: simultaneously outputting current to all electrodes 3 and controlling the direction and magnitude of the current separately; time-sharing mode: sequentially outputting current to each group of electrodes 3. Providing synchronous, independent, and time-sharing modes allows for flexible selection based on wound morphology and treatment strategy, meeting clinical needs from simple to complex wounds.

[0027] In this embodiment, the controller 2 includes a storage module and a control unit. The storage module has preset treatment modes corresponding to the wound healing stage. The treatment modes include: inflammation stage mode: high frequency, high current; proliferation stage mode: medium frequency, medium current; remodeling stage mode: low frequency, low current. The control unit calls up the treatment mode according to the wound healing stage. With the preset standardized healing stage-electric field parameter mapping library, targeted treatment can be quickly started without debugging, reducing human error and improving efficiency.

[0028] In this embodiment, the top of the dressing body 1 is covered with a flexible sealing film 4 for sealing and fixing the dressing body 1 to the wound. The flexible sealing film 4 improves the sealing environment, prevents external bacteria from entering, and at the same time firmly fixes the dressing to the wound to prevent displacement.

[0029] In this embodiment, the dressing body 1 includes an absorbent sponge 11, a polyurethane sponge 12, and a gel layer 13 arranged sequentially, with each electrode 3 disposed at the bottom of the gel layer 13. In this structure, the absorbent sponge 11 absorbs exudate, the polyurethane sponge 12 provides cushioning and rapid drying, and the gel layer 13 adheres to the wound surface, protecting newly formed tissue.

[0030] In this embodiment, the negative pressure dressing also includes a negative pressure component 5, which includes a negative pressure suction cup 51 and a negative pressure drainage tube 52. The negative pressure suction cup 51 is disposed on the flexible sealing membrane 4 and communicates with the dressing body 1. One end of the negative pressure drainage tube 52 is connected to the negative pressure suction cup 51, and the other end is connected to an external negative pressure device through a controller 2. While electrically stimulating cell migration, the wound exudate is cleared through negative pressure drainage. The two physical methods work synergistically to accelerate healing.

[0031] In this embodiment, the end of the negative pressure drainage tube 52 is provided with a negative pressure interface 521 that is connected to the controller 2. In this structure, integrated control is achieved through the negative pressure interface 521.

[0032] In this embodiment, the controller 2 is connected to each electrode 3 via wires 6, and a conduit 7 for placing the wires 6 is provided on the flexible sealing membrane 4. The conduit 7 fixes and guides the wires 6 to prevent tangling.

[0033] In this embodiment, the controller 2 is equipped with a first switch 21 for controlling the alternating pulse electric field and a second switch 22 for controlling the negative pressure. The controller 2 is also equipped with a display screen 23 for displaying various parameters. In this structure, the first switch 21 includes an electrode group selection button, a current adjustment button, and a current positive / negative conversion button. The second switch 22 includes a negative pressure adjustment button and a control switch. The electric field and negative pressure are independently controlled by the first switch 21 and the second switch 22. The display screen 23 can display treatment parameters in real time, such as current intensity, frequency, and negative pressure value, which is convenient for medical staff to monitor and record the treatment process.

[0034] Example 2: like Figure 5 As shown, the second embodiment of the negative pressure dressing based on a multi-electrode alternating pulsed electric field of the present invention is basically the same as that of embodiment 1, except that: For complex and irregular wounds, six electrodes arranged in a regular hexagon surround the wound, allowing for more detailed zoning of the wound area. Differentiated electric field therapy is then applied to each area to further improve the treatment effect.

[0035] While the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the invention. Any person skilled in the art can make many possible variations and modifications to the technical solutions of the present invention, or modify them into equivalent embodiments, without departing from the scope of the present invention. Therefore, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present invention, without departing from the scope of the present invention, should fall within the protection scope of the present invention.

Claims

1. A negative pressure dressing based on a multi-electrode alternating pulsed electric field, characterized in that: The dressing body (1), controller (2) and multiple electrodes (3) are included. Each electrode (3) is located at the bottom of the dressing body (1) and is grouped in pairs to correspond to different areas of the wound. The controller (2) is connected to each electrode (3) and periodically switches the current direction. The controller (2) selectively controls the direction and magnitude of the current output to each group of electrodes (3) to form different alternating pulse electric fields in different areas of the wound.

2. The negative pressure dressing based on a multi-electrode alternating pulsed electric field according to claim 1, characterized in that: The negative pressure dressing also includes multiple biosensors, each of which is used to collect environmental parameters of different areas of the wound. The controller (2) determines the healing stage of each area of ​​the wound based on the environmental parameters in order to control the alternating pulse electric field of each area of ​​the wound.

3. The negative pressure dressing based on a multi-electrode alternating pulse electric field according to claim 2, characterized in that: The controller (2) is configured to be at least one of the following modes: synchronous mode: output current to all electrodes (3) simultaneously; independent mode: output current to all electrodes (3) simultaneously and control the direction and magnitude of the current respectively; time-sharing mode: output current to each group of electrodes (3) in sequence.

4. The negative pressure dressing based on a multi-electrode alternating pulsed electric field according to claim 3, characterized in that: The controller (2) includes a storage module and a control unit. The storage module presets treatment modes corresponding to the wound healing stage. The treatment modes include: inflammation stage mode: high frequency, strong current; proliferation stage mode: medium frequency, medium current; remodeling stage mode: low frequency, low current. The control unit calls the treatment mode according to the wound healing stage.

5. The negative pressure dressing based on a multi-electrode alternating pulse electric field according to claim 4, characterized in that: The dressing body (1) is covered with a flexible sealing film (4) for sealing and fixing the dressing body (1) to the wound.

6. The negative pressure dressing based on a multi-electrode alternating pulsed electric field according to claim 5, characterized in that: The dressing body (1) includes an absorbent sponge (11), a polyurethane sponge (12) and a gel layer (13) arranged in sequence, and each electrode (3) is disposed at the bottom of the gel layer (13).

7. The negative pressure dressing based on a multi-electrode alternating pulsed electric field according to claim 6, characterized in that: The negative pressure dressing also includes a negative pressure component (5), which includes a negative pressure suction cup (51) and a negative pressure drainage tube (52). The negative pressure suction cup (51) is placed on a flexible sealing membrane (4) and communicates with the dressing body (1). One end of the negative pressure drainage tube (52) is connected to the negative pressure suction cup (51), and the other end is connected to an external negative pressure device through a controller (2).

8. The negative pressure dressing based on a multi-electrode alternating pulsed electric field according to claim 7, characterized in that: The negative pressure drainage tube (52) is provided with a negative pressure interface (521) at its end, which is connected to the controller (2).

9. The negative pressure dressing based on a multi-electrode alternating pulse electric field according to claim 8, characterized in that: The controller (2) is connected to each electrode (3) via wires (6), and the flexible sealing membrane (4) is provided with a conduit (7) for placing the wires (6).

10. The negative pressure dressing based on a multi-electrode alternating pulse electric field according to claim 9, characterized in that: The controller (2) is equipped with a first switch (21) for controlling the alternating pulse electric field and a second switch (22) for controlling the negative voltage. The controller (2) is also equipped with a display screen (23) for displaying various parameters.

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