A topical preparation and its preparation method

CN122557682APending Publication Date: 2026-08-14袁志公
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-05-08
Publication Date
2026-08-14

AI Technical Summary

Technical Problem

[0003]中药外用在中国有着悠久的历史,由于原料易得,制作简单、操作方便且效果好,已被人们普遍接收,现代科学大量研究证实,中药外用具有活血散寒、散结消肿、温经通络的功效,还可用于治疗各种骨关节和软组织的疼痛及麻木,其药理功效多,作用广;目前现有技术中外用中药的种类较多,但散寒镇痛、温经通络的功能并不突出,功效不明显,因此需要提供一种具有活血散寒、散结消肿、温经通络的外用制剂

Benefits of technology

[0034]本发明与现有技术相比的优点在于:本发明所提供的外用制剂是由纯中药制成的外用制剂,其通过白芷、白芨、白蔹、赤芍、当归、生地、甘草、大黄、川乌、草乌、羌活、独活、元参、苦参、乌药、木鳖子、肉桂、丁香、灵仙、木瓜、杜仲、良姜的有效配伍,经制备而成的外用制剂具有活血散寒、散结消肿、温经通络、以及消除无菌性炎症的功效,具有组成简单、配伍得当、用量较小、疗效确切等优点。

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Abstract

This invention discloses a topical preparation and its preparation method. The topical preparation is composed of the following raw materials in parts by weight: Angelica dahurica 10-15 parts, Bletilla striata 8-13 parts, Ampelopsis japonica 6-10 parts, Paeonia lactiflora 8-12 parts, Angelica sinensis 10-15 parts, Rehmannia glutinosa 6-10 parts, Glycyrrhiza uralensis 5-9 parts, Rheum palmatum 10-14 parts, Aconitum carmichaelii 8-13 parts, Aconitum kusnezoffii 8-13 parts, Notopterygium incisum 6-10 parts, Angelica pubescens 4-8 parts, Scrophularia ningpoensis 4-8 parts, Sophora flavescens 5-9 parts, Lindera strychnifolia 7-11 parts, Momordica cochinchinensis 3- 7 parts, cinnamon 2-6 parts, cloves 2-6 parts, clematis 11-13 parts, papaya 8-11 parts, eucommia 6-8 parts, galangal 7-10 parts; the preparation method of the external preparation includes the following steps: Step 1) Remove soil and impurities from the above raw materials, cut them into sections, and then grind them into powder using a pulverizer for later use; Step 2) Take the powder of each raw material according to the weight parts, put them into a container, add white wine, stir slowly into a paste, and let it stand and soak for 0.5-4 hours to obtain the external preparation.
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Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine technology, specifically to an external preparation and its preparation method. Background Technology

[0002] In Traditional Chinese Medicine (TCM), wind, cold, dampness, and heat fall under the category of "Bi syndrome." Rheumatism arises from insufficient vital energy (Qi) in the body, invasion of the meridians by wind, cold, dampness, and heat, or internal accumulation of phlegm, dampness, heat toxins, and blood stasis, leading to blockages in the meridians and causing pain, numbness, swelling, and limited flexibility in the limbs, joints, and muscles. Treatment primarily focuses on promoting blood circulation, removing blood stasis, dispelling wind, clearing the meridians, and removing turbidity and stagnation to ensure smooth flow of Qi and blood, addressing both the root cause and symptoms, and relieving pain. Currently, many Western medicines are available for treating this condition, but none can cure it completely and have significant side effects. Some patients take painkillers for extended periods to relieve temporary pain, while others take large amounts of hormones. While this may alleviate pain, improve mobility, and alleviate symptoms, the symptoms reappear and worsen once the medication is discontinued.

[0003] Traditional Chinese medicine (TCM) external application has a long history in China. Due to the availability of raw materials, simple preparation, convenient operation, and good effects, it has been widely accepted. Modern scientific research has confirmed that TCM external application has the effects of promoting blood circulation and dispelling cold, dispersing nodules and reducing swelling, and warming the meridians and promoting blood circulation. It can also be used to treat various bone and joint pain and numbness in soft tissues. Its pharmacological effects are numerous and its effects are wide-ranging. At present, there are many types of TCM external application in existing technology, but the functions of dispelling cold and relieving pain, and warming the meridians and promoting blood circulation are not prominent and the effects are not obvious. Therefore, there is a need to provide an external preparation with the functions of promoting blood circulation and dispelling cold, dispersing nodules and reducing swelling, and warming the meridians and promoting blood circulation. Summary of the Invention

[0004] The technical problem to be solved by the present invention is to overcome the defects of the above-mentioned technology and provide a topical preparation and its preparation method.

[0005] To solve the above-mentioned technical problems, the present invention provides a topical preparation, which is composed of the following raw materials in parts by weight: Angelica dahurica 10-15 parts, Bletilla striata 8-13 parts, Ampelopsis japonica 6-10 parts, Paeonia lactiflora 8-12 parts, Angelica sinensis 10-15 parts, Rehmannia glutinosa 6-10 parts, Glycyrrhiza uralensis 5-9 parts, Rheum palmatum 10-14 parts, Aconitum carmichaelii 8-13 parts, Aconitum kusnezoffii 8-13 parts, Notopterygium incisum 6-10 parts, Angelica pubescens 4-8 parts, Scrophularia ningpoensis 4-8 parts, Sophora flavescens 5-9 parts, Lindera strychnifolia 7-11 parts, Momordica cochinchinensis 3-7 parts, Cinnamomum cassia 2-6 parts, Syzygium aromaticum 2-6 parts, Clematis chinensis 11-13 parts, Chaenomeles speciosa 8-11 parts, Eucommia ulmoides 6-8 parts, and Alpinia officinarum 7-10 parts.

[0006] Furthermore, it is composed of the following ingredients in parts by weight: Angelica dahurica 13 parts, Bletilla striata 11 parts, Ampelopsis japonica 8 parts, Paeonia lactiflora 10 parts, Angelica sinensis 13 parts, Rehmannia glutinosa 8 parts, Glycyrrhiza uralensis 7 parts, Rheum palmatum 13 parts, Aconitum carmichaelii 10 parts, Aconitum kusnezoffii 10 parts, Notopterygium incisum 9 parts, Angelica pubescens 6 parts, Scrophularia ningpoensis 7 parts, Sophora flavescens 8 parts, Lindera strychnifolia 8 parts, Momordica cochinchinensis 5 parts, Cinnamomum cassia 4 parts, Syzygium aromaticum 4 parts, Clematis chinensis 13 parts, Chaenomeles speciosa 10 parts, Eucommia ulmoides 7 parts, Alpinia officinarum 9 parts.

[0007] Furthermore, the preparation method of the topical preparation includes the following steps:

[0008] Step 1) Remove soil and impurities from the above raw materials, cut them into sections, and then grind them into powder using a grinder for later use;

[0009] Step 2) Take the powder of each raw material according to the weight proportions, put them into a container, add white wine, stir slowly into a paste, and let it stand and soak for 0.5-4 hours to obtain the external preparation.

[0010] Furthermore, the alcohol content of the liquor is not less than 50 degrees.

[0011] The raw materials used in this invention are sourced from the following sources:

[0012] Angelica dahurica: pungent in taste and warm in nature; enters the lung, spleen and stomach meridians; relieves exterior syndromes and dispels cold, dispels wind and relieves pain, clears nasal passages, dries dampness and stops leukorrhea, reduces swelling and drains pus, dispels wind and relieves itching; used for wind-cold common cold, headache, toothache, rheumatic pain, sinusitis, leukorrhea, carbuncles and boils.

[0013] Bletilla striata: bitter, sweet, astringent, slightly cold; enters the lung, liver, and stomach meridians; astringent and hemostatic, reduces swelling and promotes tissue regeneration; used for hemoptysis, hematemesis, traumatic bleeding, carbuncles and boils, and chapped skin.

[0014] Bai Lian: bitter, slightly cold; enters the heart and stomach meridians; clears heat and detoxifies, eliminates carbuncles and dissipates nodules, promotes wound healing and tissue regeneration; used for carbuncles, boils, scrofula, burns and scalds.

[0015] Red peony root: bitter in taste and slightly cold in nature; enters the liver meridian; clears heat and cools blood, disperses blood stasis and relieves pain; used for heat entering the blood, febrile rashes, hematemesis and epistaxis, red and swollen eyes, liver stagnation and hypochondriac pain, amenorrhea and dysmenorrhea, abdominal masses and pain, traumatic injuries, carbuncles and sores.

[0016] Angelica sinensis: sweet and pungent in taste, warm in nature; enters the liver, heart and spleen meridians; nourishes blood and promotes blood circulation, regulates menstruation and relieves pain, moistens the intestines and promotes bowel movement; used for blood deficiency and chlorosis, dizziness and palpitations, irregular menstruation, amenorrhea and dysmenorrhea, abdominal pain due to deficiency and cold, rheumatic arthralgia, traumatic injuries, carbuncles and sores, and constipation due to intestinal dryness.

[0017] Rehmannia glutinosa: Sweet, bitter, and slightly cold in nature; enters the heart, liver, and kidney meridians; nourishes yin and clears heat, cools blood and replenishes blood; mainly used for feverish thirst, internal heat and thirst, bone steaming fever, febrile diseases with rashes, hematemesis, metrorrhagia, hematuria, hematochezia caused by blood heat, anemia and chlorosis, dizziness and palpitations, and amenorrhea due to insufficient blood.

[0018] Licorice: Sweet in taste and neutral in nature; enters the heart, lung, spleen, and stomach meridians; tonifies the spleen and replenishes qi, clears heat and detoxifies, eliminates phlegm and stops cough, relieves spasms and pain, and harmonizes other medicines; used for spleen and stomach weakness, fatigue, palpitations and shortness of breath, cough with excessive phlegm, abdominal and limb spasms and pain, carbuncles and boils, and to alleviate the toxicity and severity of other medicines.

[0019] Rhubarb: Bitter, cold; enters the spleen, stomach, large intestine, liver, and pericardium meridians; clears heat and unblocks the intestines, cools the blood and detoxifies, removes blood stasis and unblocks menstruation. Used for constipation due to excess heat, abdominal pain due to stagnation, incomplete diarrhea, jaundice due to damp heat, hematemesis due to blood heat, red eyes, swollen throat, abdominal pain due to intestinal abscess, boils and carbuncles, amenorrhea due to blood stasis, and traumatic injuries.

[0020] Aconitum carmichaelii: It is pungent and bitter in taste, and hot in nature; it enters the heart, liver, kidney and spleen meridians; it dispels wind and dampness, warms the meridians and relieves pain; it is used for wind-cold-dampness arthralgia, joint pain, cold pain in the heart and abdomen, cold hernia pain and anesthesia and analgesia.

[0021] Aconitum carmichaelii: It is pungent and bitter in taste and hot in nature; it enters the heart, liver, kidney and spleen meridians; it dispels wind and dampness, warms the meridians and relieves pain; it is used for wind-cold-dampness arthralgia, joint pain, cold pain in the heart and abdomen, cold hernia pain and anesthesia and analgesia.

[0022] Notopterygium root: It has a pungent and bitter taste and is warm in nature; it enters the bladder and kidney meridians; it relieves exterior syndromes and dispels cold, dispels wind and dampness, and relieves pain; it is used to treat colds caused by wind and cold, wind-cold-dampness arthralgia, stiff neck and muscle spasms, joint pain, edema caused by wind, carbuncles and boils.

[0023] Angelica pubescens: It has a pungent and bitter taste and is slightly warm in nature; it enters the kidney and bladder meridians; it dispels wind and dampness, relieves pain and numbness; it is used for wind-cold-dampness arthralgia, lower back and knee pain, headache due to latent wind in the Shaoyin meridian, and headache due to wind-cold and dampness.

[0024] Scrophularia: Sweet, bitter, and salty in taste, slightly cold in nature; enters the lung, stomach, and kidney meridians; clears heat and cools blood, nourishes yin and reduces fire, relieves irritability, and detoxifies; treats yin deficiency caused by febrile diseases, dry tongue and thirst, rashes, bone steaming fever, restlessness at night, spontaneous sweating and night sweats, constipation due to fluid depletion, hematemesis and epistaxis, sore throat, carbuncles, scrofula, febrile rashes, red eyes, diphtheria, and sores.

[0025] Sophora flavescens: bitter in taste and cold in nature; enters the heart, liver, stomach, large intestine and bladder meridians; clears heat and dries dampness, kills parasites and promotes diuresis; used for dysentery, hematochezia, jaundice and urinary retention, leukorrhea, vulvar swelling and itching, eczema, wet sores, pruritus, scabies and leprosy.

[0026] Lindera root: pungent, warm; enters the lung, spleen, kidney, and bladder meridians; promotes qi circulation and relieves pain, warms the kidneys and dispels cold; used for cold stagnation of qi, chest and abdominal distension and pain, shortness of breath, cold bladder, enuresis and frequent urination, hernia pain, and abdominal pain due to cold in menstruation.

[0027] Momordica cochinchinensis seeds: bitter, slightly sweet, cool, and toxic; enters the liver, spleen, and stomach meridians; disperses nodules and reduces swelling, attacks toxins and heals sores; treats sores, carbuncles, mastitis, scrofula, hemorrhoids, fistulas, tinea, and tinea capitis.

[0028] Cinnamon: It has a pungent and sweet taste and is very hot in nature; it enters the kidney, spleen, heart and liver meridians; it has the effects of tonifying fire and assisting yang, guiding fire back to its source, dispelling cold and relieving pain, and warming and unblocking the meridians; it is used for impotence and cold uterus, cold pain in the waist and knees, kidney deficiency and wheezing, floating of deficient yang, dizziness and red eyes, cold pain in the heart and abdomen, vomiting and diarrhea due to deficiency and cold, abdominal pain due to cold hernia, dysmenorrhea and amenorrhea.

[0029] Clove: It has a pungent taste and warm properties; it enters the spleen, stomach, lung, and kidney meridians; it has the effects of warming the middle and relieving nausea, tonifying the kidney and assisting yang; it is used for spleen and stomach deficiency and cold, hiccups and vomiting, poor appetite and diarrhea, cold pain in the heart and abdomen, and impotence due to kidney deficiency.

[0030] Lingxian: It tastes pungent, salty, and slightly bitter; it is warm in nature and slightly toxic; it enters the bladder and liver meridians; it dispels wind and dampness, unblocks the meridians and relieves pain, eliminates phlegm and saliva, and disperses masses; it treats gout, stubborn numbness, cold pain in the waist and knees, beriberi, malaria, masses and accumulations, tetanus, tonsillitis, and fishbone stuck in the throat.

[0031] Papaya: Sour in taste and warm in nature; enters the liver and spleen meridians; has the effects of relaxing muscles and tendons, harmonizing the stomach and resolving dampness; used to treat dampness-induced arthralgia, lower back and knee pain, summer heat and dampness causing vomiting and diarrhea, muscle spasms and pain, beriberi and edema.

[0032] Eucommia ulmoides: sweet and slightly pungent, warm; enters the liver and kidney meridians; tonifies the liver and kidneys, strengthens tendons and bones, and calms the fetus; treats soreness and pain in the lower back and spine, weakness in the legs and knees, dribbling urination, dampness and itching in the genital area, threatened miscarriage, restless fetal movement, and high blood pressure.

[0033] Galangal: pungent and hot; enters the spleen and stomach meridians; warms the stomach, dispels wind, disperses cold, promotes qi circulation, and relieves pain; treats cold in the spleen and stomach, cold pain in the epigastrium and abdomen, vomiting and diarrhea, dysphagia and nausea, food stagnation, malaria, and cold stagnation.

[0034] The advantages of this invention compared to existing technologies are as follows: The external preparation provided by this invention is a pure Chinese herbal medicine preparation. It is prepared by effectively combining Angelica dahurica, Bletilla striata, Ampelopsis japonica, Paeonia lactiflora, Angelica sinensis, Rehmannia glutinosa, Glycyrrhiza uralensis, Rheum palmatum, Aconitum carmichaelii, Aconitum kusnezoffii, Notopterygium incisum, Angelica pubescens, Scrophularia ningpoensis, Sophora flavescens, Lindera strychnifolia, Momordica cochinchinensis, Cinnamomum cassia, Syzygium aromaticum, Clematis chinensis, Chaenomeles speciosa, Eucommia ulmoides, and Alpinia officinarum. The external preparation prepared by this invention has the effects of promoting blood circulation and dispelling cold, dispersing nodules and reducing swelling, warming the meridians and promoting blood circulation, and eliminating aseptic inflammation. It has the advantages of simple composition, proper compatibility, small dosage, and definite curative effect. Detailed Implementation

[0035] The following detailed description of a topical preparation and its preparation method according to the present invention is provided in conjunction with embodiments.

[0036] Example 1

[0037] A topical preparation is composed of the following raw materials in parts by weight: Angelica dahurica 13 parts, Bletilla striata 11 parts, Ampelopsis japonica 8 parts, Paeonia lactiflora 10 parts, Angelica sinensis 13 parts, Rehmannia glutinosa 8 parts, Glycyrrhiza uralensis 7 parts, Rheum palmatum 13 parts, Aconitum carmichaelii 10 parts, Aconitum kusnezoffii 10 parts, Notopterygium incisum 9 parts, Angelica pubescens 6 parts, Scrophularia ningpoensis 7 parts, Sophora flavescens 8 parts, Lindera strychnifolia 8 parts, Momordica cochinchinensis 5 parts, Cinnamomum cassia 4 parts, Syzygium aromaticum 4 parts, Clematis chinensis 13 parts, Chaenomeles speciosa 10 parts, Eucommia ulmoides 7 parts, Alpinia officinarum 9 parts;

[0038] The preparation method of the topical preparation includes the following steps:

[0039] Step 1) Remove soil and impurities from the above raw materials, cut them into sections, and then grind them into powder using a grinder for later use;

[0040] Step 2) Take the powder of each raw material according to the weight proportions, put them into a container, add white wine with an alcohol content of not less than 50 degrees, stir slowly into a paste, and let it stand and soak for 0.5-4 hours to obtain the external preparation.

[0041] Applicable conditions: various neck, shoulder, back and leg pains, rheumatic hyperplasia, numbness in the limbs, gynecological diseases, and sub-healthy individuals;

[0042] Instructions for use: Take the external preparation of Example 1, i.e., the paste, as prescribed by your doctor, put it into a gauze bag, apply it to the affected area or acupoint, and cover the top surface of the gauze bag with plastic film; then take an appropriate amount of coarse salt with large particles, heat it to 40-60℃, press it on the plastic film, and apply the hot compress for 40 minutes; after the affected area or acupoint is heated, the pores will open, allowing the medicinal power to penetrate better and facilitating the patient's absorption of the medicinal power.

[0043] The present invention and its embodiments have been described above, and such description is not restrictive. In conclusion, if those skilled in the art are inspired by this description and design similar structures and embodiments without departing from the spirit of the invention, such designs should fall within the protection scope of the present invention.

Claims

1. A topical preparation, characterized in that, It is composed of the following ingredients in parts by weight: Angelica dahurica 10-15 parts, Bletilla striata 8-13 parts, Ampelopsis japonica 6-10 parts, Paeonia lactiflora 8-12 parts, Angelica sinensis 10-15 parts, Rehmannia glutinosa 6-10 parts, Glycyrrhiza uralensis 5-9 parts, Rheum palmatum 10-14 parts, Aconitum carmichaelii 8-13 parts, Aconitum kusnezoffii 8-13 parts, Notopterygium incisum 6-10 parts, Angelica pubescens 4-8 parts, Scrophularia ningpoensis 4-8 parts, Sophora flavescens 5-9 parts, Lindera strychnifolia 7-11 parts, Momordica cochinchinensis 3-7 parts, Cinnamomum cassia 2-6 parts, Syzygium aromaticum 2-6 parts, Clematis chinensis 11-13 parts, Chaenomeles speciosa 8-11 parts, Eucommia ulmoides 6-8 parts, Alpinia officinarum 7-10 parts.

2. The topical preparation according to claim 1, characterized in that, It is composed of the following ingredients in parts by weight: Angelica dahurica 13 parts, Bletilla striata 11 parts, Ampelopsis japonica 8 parts, Paeonia lactiflora 10 parts, Angelica sinensis 13 parts, Rehmannia glutinosa 8 parts, Glycyrrhiza uralensis 7 parts, Rheum palmatum 13 parts, Aconitum carmichaelii 10 parts, Aconitum kusnezoffii 10 parts, Notopterygium incisum 9 parts, Angelica pubescens 6 parts, Scrophularia ningpoensis 7 parts, Sophora flavescens 8 parts, Lindera strychnifolia 8 parts, Momordica cochinchinensis 5 parts, Cinnamomum cassia 4 parts, Syzygium aromaticum 4 parts, Clematis chinensis 13 parts, Chaenomeles speciosa 10 parts, Eucommia ulmoides 7 parts, Alpinia officinarum 9 parts.

3. The method for preparing the topical preparation according to any one of claims 1-2, characterized in that, Includes the following steps: Step 1) Remove soil and impurities from the above raw materials, cut them into sections, and then grind them into powder using a grinder for later use; Step 2) Take the powder of each raw material according to the weight proportions, put them into a container, add white wine, stir slowly into a paste, and let it stand and soak for 0.5-4 hours to obtain the external preparation.

4. The method for preparing the topical preparation according to claim 3, characterized in that, The alcohol content of the liquor is not less than 50 degrees.