An automated sample dispensing and mixing device for a test kit

Abstract

This invention discloses an automatic sample addition and mixing device for a test kit, belonging to the field of in vitro diagnostic testing technology. When the pendulum rotates with the main shaft and generates eccentric oscillations, the guide rod transmits the motion, causing the entire worktable to produce multi-angle composite oscillations. This causes the disposable test kit placed on top to follow suit with uniform, stable, small-amplitude high-frequency or large-amplitude low-frequency oscillations. Furthermore, by changing the horizontal position of the adjustment plate and pushing or pulling the pendulum via the edge-hinged pull rod, the deflection angle of the pendulum can be adjusted. Combined with the transmission action of the main shaft, the oscillation amplitude of the pendulum can be adjusted. The bottom ball of the guide rod, fixed at the center of the bottom of the worktable, is slidably connected to the annular groove of the pendulum. The multi-angle oscillation of the pendulum is synchronously transmitted to the worktable through the guide rod, causing the worktable and the test kit on top to perform high-frequency small-amplitude or low-frequency large-amplitude composite oscillations. This completely eliminates reagent mixing dead zones, achieving full fusion of samples and reagents and improving the accuracy of subsequent testing.

Description

Technical Field

[0001] This invention belongs to the field of in vitro diagnostic testing technology, and particularly relates to an automatic sample addition and mixing device for a test kit. Background Technology

[0002] In vitro diagnostic testing is a core technology for modern medical screening, disease diagnosis, epidemic prevention and control, and biomedical research. Reagent kit testing is widely used in many fields such as clinical testing, food safety testing, pathogen screening, and biochemical indicator testing due to its advantages such as convenient operation, rapid detection, wide applicability, and controllable cost.

[0003] Currently, reagent kit testing mainly operates in two modes: manual operation and traditional semi-automatic equipment operation. Manual operation relies on laboratory personnel to manually add samples using pipettes and mix them by hand by shaking, swaying, and inverting. This operation is cumbersome and inefficient. To overcome the shortcomings of manual operation, mechanization has been implemented to replace the process and reduce human intervention. However, the mixing mechanism and the detection mechanism are mostly separate and independent designs. The two processes still require manual transfer of reagent kits and manual connection, resulting in low equipment integration and the inability to achieve continuous production line operation. Moreover, traditional mixing equipment has a single mixing mode and cannot adaptively adjust the mixing mode according to reagent viscosity, sample volume, and sample characteristics. It has poor mixing effect for trace amounts and high-viscosity reagents, with mixing dead zones and difficulty in ensuring uniformity, which affects the accuracy of test results. To solve the above problems, there is an urgent need for an automatic sample addition and mixing device for reagent kits. Summary of the Invention

[0004] The purpose of this invention is to address the problems that mixing and detection mechanisms are often designed separately; and that traditional mixing equipment has a single mixing mode and cannot adaptively adjust the mixing mode according to reagent viscosity, sample volume, and sample characteristics, resulting in poor mixing effect and the existence of mixing dead zones for trace amounts and high-viscosity reagents. Therefore, an automatic sample addition and mixing device for test kits is proposed.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] An automated sample dispensing and mixing device for a test kit includes: a frame, a support platform fixed on the frame, two slides and a through hole on the support platform, the through hole being located between the two slides, a worktable on the support platform, an automated sample dispensing component above the worktable, the automated sample dispensing component being mounted on the support platform, a sliding support component slidably mounted on the bottom of the worktable, the sliding support component sliding through the two slides, two support seats slidably mounted on the bottom of the sliding support component, the support seats being fixed to the bottom of the frame, an adjustment component being installed through the inside of the worktable, correction components being installed at the four corners of the adjustment component, a guide rod fixed at the center of the bottom of the worktable, the guide rod being disposed through the through hole, and a mixing component being connected to the bottom end of the guide rod, the mixing component being installed inside the sliding support component, a toothed frame fixed on one side of the bottom of the support platform, one end of the mixing component penetrating the sliding support component and engaging with the inside of the toothed frame.

[0007] As a further description of the above technical solution:

[0008] The automatic sample dispensing assembly includes a workstation frame, which is fixed on a support platform. The front and rear sides of the workstation frame are respectively provided with a sample dispensing station and a testing station. Two electric telescopic rods are fixed in the sample dispensing station. An automatic liquid dispensing device is fixed at the bottom of the two electric telescopic rods. Several sample dispensing needles are provided at the bottom of the automatic liquid dispensing device, and the sample dispensing needles are located above the worktable.

[0009] As a further description of the above technical solution:

[0010] The sliding support assembly includes a slide block, which is U-shaped and slides through two slide tracks. The extended part of the bottom of the slide block is fixed with multi-stage hydraulic push rods. The other end of the multi-stage hydraulic push rods is fixed in the frame. T-shaped limiting grooves are provided on both sides of the bottom of the slide block, and the T-shaped protrusion on the top of the support base slides in the limiting grooves.

[0011] As a further description of the above technical solution:

[0012] Two guide rods slide through the slide block. The guide rods are fixed on both sides of the bottom of the worktable. Springs are sleeved on both sides of the outside of the guide rods. The springs are fixed between the slide block and the bottom of the worktable.

[0013] As a further description of the above technical solution:

[0014] The adjustment assembly includes a bidirectional lead screw, the two ends of which are rotated through bushings in the worktable and are fixed with a handle. Nuts are threaded to both sides of the outer side of the bidirectional lead screw. The nuts are slidably connected in guide grooves opened in the worktable. A slide plate is fixed to the top of the nut. T-shaped sliders are fixed to both sides of the bottom of the slide plate. The sliders are slidably connected in T-shaped grooves opened in the worktable.

[0015] As a further description of the above technical solution:

[0016] The correction assembly includes an L-shaped bracket, with a rotating shaft fixed at the right-angle end of the L-shaped bracket. The bottom end of the rotating shaft is rotatably connected to a placement groove opened at the end of the slide plate via a bushing. A torsion spring is sleeved on the outside of the rotating shaft, with both ends of the torsion spring fixed to the outside of the rotating shaft and the bottom of the placement groove at the end of the slide plate. Pressure rollers are installed at both ends of the L-shaped bracket.

[0017] As a further description of the above technical solution:

[0018] The mixing assembly includes a main shaft, the two ends of which are rotatably connected to the inside of the slide via bushings. One end of the main shaft passes through the slide and is fixed with a gear. The gear is located inside a gear frame. The gear frame is U-shaped and has several tooth blocks at the bottom of its inner wall. The bottom of the gear corresponds to the position of the tooth blocks, and the gear is not engaged with the tooth blocks in the current state.

[0019] As a further description of the above technical solution:

[0020] A swing plate and an adjusting plate are slidably sleeved on the outside of the main shaft. An annular groove is formed on the outside of the swing plate and the adjusting plate. The ball at the bottom of the guide rod is slidably connected within the annular groove of the swing plate. A clearance groove is formed on the outside of the main shaft, and a strip-shaped clearance hole is formed in the middle of the swing plate. The clearance hole contacts the clearance groove. A rotating shaft is fixedly inserted through the main shaft at a position corresponding to the clearance groove. Both ends of the rotating shaft are sleeved and rotate inside the swing plate. A strip plate is fixed on the outside of the main shaft. A groove on the inner wall of the adjusting plate slides outside the strip plate. An adjusting wheel is slidably connected within the annular groove of the adjusting plate. An electric push rod is installed at one end of the adjusting wheel. The electric push rod is fixed to one side of the inner wall of the slide block. A pull rod is rotatably connected to the edges of the opposite surfaces of the swing plate and the adjusting plate via a pin.

[0021] In summary, due to the adoption of the above technical solution, the beneficial effects of the present invention are: 1. In this invention, the gear at the end of the main shaft slides into the U-shaped gear frame, and the gear teeth gradually mesh with the bottom teeth of the gear frame. During the rotation of the gear, the main shaft rotates coaxially. The main shaft slides with the groove on the inner wall of the adjustment plate through the outer fixed strip plate, so that the adjustment plate and the main shaft can rotate synchronously. With the sliding contact between the clearance groove and the clearance hole, the main shaft transmits the driving force to the swing plate, so that the adjustment plate and the swing plate rotate synchronously with the main shaft, and the swing plate can swing relative to the main shaft. The surface of the swing plate is provided with an annular sliding groove, and the bottom ball of the guide rod fixed at the center of the bottom of the worktable slides into the annular sliding groove, forming a spherical follow-up transmission structure. When the oscillating disk rotates with the main shaft and produces an eccentric oscillation, the guide ball rod transmits the motion, causing the entire worktable to generate a multi-angle composite oscillation motion. This causes the disposable reagent kit placed on top to follow suit with uniform, stable, small-amplitude high-frequency or large-amplitude low-frequency oscillations. Furthermore, by changing the horizontal position of the adjustment plate and pushing or pulling the oscillating disk through the edge-hinged pull rod, the deflection angle of the oscillating disk can be adjusted. Combined with the transmission action of the main shaft, the oscillation amplitude of the oscillating disk can be adjusted. The ball at the bottom of the guide ball rod, fixed at the center of the bottom of the worktable, is slidably connected to the annular groove of the oscillating disk. The multi-angle oscillation of the oscillating disk is synchronously transmitted to the worktable through the guide ball rod, causing the worktable and the reagent kit on top to perform a high-frequency small-amplitude or low-frequency large-amplitude composite oscillation motion. This completely eliminates reagent mixing dead zones, achieves full fusion of samples and reagents, and improves the accuracy of subsequent detection. 2. In this invention, by driving the bidirectional lead screw to rotate, the nuts connected by threads on both sides slide symmetrically along the guide groove of the worktable. Simultaneously, the nuts drive the top sliding plate to move horizontally. The sliding plate, through the limiting cooperation between the bottom T-shaped slider and the T-shaped groove of the worktable, ensures smooth and non-offset translation. The distance between the two sliding plates can be precisely adjusted according to the size of different reagent kits to accommodate reagent kits of different widths. After the sliding plates are adjusted to the correct position, the correction components at the four corners simultaneously complete the all-round correction and limiting of the reagent kit. The L-shaped bracket of the correction component can achieve small-angle adaptive rotation through the rotating shaft. Combined with the torsion spring sleeved outside the rotating shaft, it always provides elastic reset constraint force to the L-shaped bracket, ensuring that the pressure rollers at the ends tightly fit the outer walls of the four corners of the reagent kit. Utilizing the elastic compression and limiting structure of the four sets of correction components, automatically centering and correcting misplaced or tilted reagent kits can be achieved, completely eliminating reagent kit placement deviations and avoiding problems such as inaccurate alignment, missed addition, or off-center addition during subsequent sample addition. Attached Figure Description

[0022] Figure 1 This is a three-dimensional structural diagram of an automatic sample addition and mixing device for a test kit proposed in this invention;

[0023] Figure 2 This is a schematic diagram of the automatic sample dispensing component of an automatic sample dispensing and mixing device for a test kit proposed in this invention;

[0024] Figure 3This is a side view of the support platform structure of an automatic sample dispensing and mixing device for a test kit proposed in this invention;

[0025] Figure 4 This is a schematic diagram of the sliding support component structure of an automatic sample dispensing and mixing device for a test kit proposed in this invention;

[0026] Figure 5 This is a schematic diagram of the adjustment component structure of an automatic sample addition and mixing device for a test kit proposed in this invention;

[0027] Figure 6 This is a schematic diagram of the correction component structure of an automatic sample addition and mixing device for a test kit proposed in this invention;

[0028] Figure 7 This is a schematic diagram of the mixing component structure of an automatic sample addition and mixing device for a test kit proposed in this invention;

[0029] Figure 8 This is a schematic diagram of the tray structure of an automatic sample addition and mixing device for a test kit proposed in this invention.

[0030] Legend: 1. Frame; 2. Support platform; 3. Slide rail; 4. Through hole; 5. Worktable; 6. Automatic sample dispensing assembly; 601. Station frame; 602. Sample dispensing station; 603. Testing station; 604. Electric telescopic rod; 605. Automatic liquid dispensing device; 606. Sample dispensing needle; 7. Sliding support assembly; 701. Slide seat; 702. Multi-stage hydraulic push rod; 703. Limiting groove; 704. Guide rod; 705. Spring; 8. Support base; 9. Adjustment assembly; 901. Two-way lead screw; 902. Rotary handle ; 903, Nut; 904, Slide plate; 905, Slider; 10, Correction assembly; 101, L-shaped bracket; 102, Rotating shaft; 103, Torsion spring; 104, Pressure roller; 11, Guide ball rod; 12, Mixing assembly; 121, Main shaft; 122, Gear; 123, Swivel plate; 124, Adjusting plate; 125, Clearance groove; 126, Strip plate; 127, Clearance hole; 128, Rotating shaft; 129, Pull rod; 1291, Adjusting wheel; 1292, Electric push rod; 13, Gear frame. Detailed Implementation

[0031] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0032] In its specific implementation, such as Figures 1-8 The present invention provides a technical solution:

[0033] An automated sample dispensing and mixing device for a test kit includes: a frame 1, a support platform 2 fixed on the frame 1, two slide rails 3 and a through hole 4 formed on the support platform 2, the through hole 4 being located between the two slide rails 3, a worktable 5 on the support platform 2, an automated sample dispensing component 6 above the worktable 5, the automated sample dispensing component 6 being mounted on the support platform 2, the automated sample dispensing component 6 including a station frame 601 fixed on the support platform 2, and sample dispensing stations 602 and detection stations respectively located on the front and rear sides of the station frame 601. 603. Two electrically operated telescopic rods 604 are fixed in the sample dispensing station 602. An automatic dispensing unit 605 is fixed to the bottom of the two electric telescopic rods 604. Several dispensing needles 606 are provided at the bottom of the automatic dispensing unit 605, and the dispensing needles 606 are located above the workbench 5. The two sets of electric telescopic rods 604 at the bottom of the station frame 601 extend and retract synchronously downwards, driving the automatic dispensing unit 605 at the bottom to move down as a whole, so that the array of dispensing needles 606 at the bottom are precisely aligned with each reaction well of the reagent kit. The automatic dispensing unit 605 completes the quantitative aspiration and precise dispensing of reagents and samples, completing the automatic dispensing operation of all wells of the reagent kit, avoiding the dosage error and operation deviation of manual dispensing, and ensuring the consistency of dispensing.

[0034] A sliding support assembly 7 is slidably mounted on the bottom of the worktable 5. The sliding support assembly 7 slides through two slide rails 3. Two support seats 8 are slidably mounted on the bottom of the sliding support assembly 7. The support seats 8 are fixed to the bottom of the frame 1. The sliding support assembly 7 includes a slide 701, which is U-shaped and slides through the two slide rails 3. A multi-stage hydraulic push rod 702 is fixed to the extended part of the bottom of the slide 701. The other end of the multi-stage hydraulic push rod 702 is fixed in the frame 1. The bottom of the slide 701... The two sides of the support 8 are provided with T-shaped limiting grooves 703, and the T-shaped protrusion on the top of the support 8 slides in the limiting grooves 703. The slide 701 adopts a U-shaped structure and is slidably assembled in the two sets of slides 3 of the support platform 2. The multi-stage hydraulic push rod 702 at the bottom of the slide 701 is driven to extend and retract, providing power for the overall transfer. At the same time, the T-shaped protrusion on the top of the support 8 slides and cooperates with the T-shaped limiting groove 703 at the bottom of the slide 701 to limit and guide the transfer stroke of the slide 701, ensuring that the worktable 5 is transferred horizontally smoothly and without shaking.

[0035] Two guide rods 704 slide through the slide 701. The guide rods 704 are fixed to both sides of the bottom of the worktable 5. Springs 705 are sleeved on both sides of the guide rods 704, and the springs 705 are fixed between the slide 701 and the bottom of the worktable 5. During the shake of the reagent kit, the guide rods 704 on both sides of the bottom of the worktable 5 slide through the slide 701. Together with the springs 705 sleeved on the outside of the guide rods 704, they form an elastic buffer structure to prevent air bubbles and reagent splashing caused by violent shaking.

[0036] An adjustment assembly 9 is installed through the interior of the worktable 5. Correction assemblies 10 are installed at the four corners of the adjustment assembly 9. The adjustment assembly 9 includes a double-acting lead screw 901. Both ends of the double-acting lead screw 901 rotate through the worktable 5 via bushings and are fixed with handles 902. Nuts 903 are threaded onto both sides of the outer surface of the double-acting lead screw 901. The nuts 903 are slidably connected in guide grooves on the worktable 5. A slide plate 904 is fixed to the top of the nut 903, and T-shaped sliding brackets are fixed to both sides of the bottom of the slide plate 904. Block 905 and slider 905 are slidably connected in the T-shaped groove opened on the worktable 5; drive the bidirectional lead screw 901 to rotate, causing the nuts 903 connected by threads on both sides to slide symmetrically along the guide groove of the worktable 5. The nuts 903 simultaneously drive the top slide plate 904 to move horizontally. The slide plate 904 is limited by the bottom T-shaped slider 905 and the T-shaped groove of the worktable 5 to ensure that the horizontal movement is smooth and without deviation. The distance between the two slide plates 904 can be precisely adjusted according to the size of reagent kits of different specifications to adapt to the placement requirements of reagent kits of different widths.

[0037] The alignment component 10 includes an L-shaped bracket 101. A rotating shaft 102 is fixed to the right-angle end of the L-shaped bracket 101. The bottom end of the rotating shaft 102 is rotatably connected to a placement groove at the end of the slide plate 904 via a bushing. A torsion spring 103 is sleeved on the outside of the rotating shaft 102. The two ends of the torsion spring 103 are fixed to the outside of the rotating shaft 102 and the bottom of the placement groove at the end of the slide plate 904. Pressure rollers 104 are installed at both ends of the L-shaped bracket 101. The L-shaped bracket 101 of the alignment component 10 can achieve small-angle adaptive rotation through the rotating shaft 102. With the help of the torsion spring 103 sleeved on the outside of the rotating shaft 102, it always provides an elastic reset constraint force for the L-shaped bracket 101, so that the pressure rollers 104 at the ends are tightly attached to the outer walls of the four corners of the reagent kit. By using the elastic clamping and limiting structure of the four sets of alignment components 10, the alignment of the reagent kit that is misplaced or tilted can be automatically centered and corrected, eliminating the placement deviation of the reagent kit.

[0038] A guide ball rod 11 is fixed at the center of the bottom of the workbench 5. The guide ball rod 11 is inserted through the through hole 4, and the bottom end of the guide ball rod 11 is connected to a mixing component 12. The mixing component 12 is installed inside the sliding support component 7. A toothed frame 13 is fixed on one side of the bottom of the support platform 2. One end of the mixing component 12 passes through the sliding support component 7 and meshes with the inside of the toothed frame 13.

[0039] The mixing assembly 12 includes a main shaft 121. Both ends of the main shaft 121 are rotatably connected to the inside of the slide block 701 via bushings. One end of the main shaft 121 passes through the slide block 701 and is fixed with a gear 122. The gear 122 is located inside the gear frame 13. The gear frame 13 has a U-shaped design and several tooth blocks are provided at the bottom of the inner wall. The bottom of the gear 122 corresponds to the position of the tooth blocks, and the gear 122 is not engaged with the tooth blocks in the current state. The gear 122 at the end of the main shaft 121 slides into the U-shaped gear frame 13. The teeth of the gear 122 gradually mesh with the tooth blocks at the bottom of the gear frame 13. The horizontal linear motion of the slide block 701 is converted into the passive rotational power of the gear 122. During the rotation of the gear 122, the main shaft 121 is synchronously driven to rotate coaxially.

[0040] A swing plate 123 and an adjusting plate 124 are slidably sleeved on the outside of the main shaft 121. The swing plate 123 and the adjusting plate 124 are provided with annular grooves. The ball at the bottom of the guide rod 11 is slidably connected in the annular groove in the swing plate 123. A clearance groove 125 is provided on the outside of the main shaft 121, and a strip-shaped clearance hole 127 is provided in the middle of the swing plate 123. The clearance hole 127 contacts the clearance groove 125. A rotating shaft 128 is fixed through the main shaft 121 at the position corresponding to the clearance groove 125. The two ends of the rotating shaft 128 are sleeved and rotate inside the swing plate 123. A strip plate 126 is fixed on the outside of the main shaft 121. The groove on the inner wall of the adjusting plate 124 slides outside the strip plate 126. The main spindle 121 slides with the groove on the inner wall of the adjusting plate 124 via the strip plate 126 fixed on the outside, so that the adjusting plate 124 and the main spindle 121 can rotate synchronously. With the sliding contact of the clearance groove 125 and the clearance hole 127, the main spindle 121 transmits the driving force to the swing plate 123, so that the adjusting plate 124 and the swing plate 123 rotate synchronously around the main spindle 121. At the same time, the clearance groove 125 is opened on the outer wall of the main spindle 121 and the clearance hole 127 is set in the middle of the swing plate 123. With the rotation shaft 128 fixed inside the main spindle 121 and the swing plate 123 rotatably connected, the swing plate 123 can swing relative to the main spindle 121 at an angle. The surface of the swing plate 123 is provided with an annular sliding groove. The bottom ball of the guide rod 11 fixed at the bottom center of the worktable 5 slides and is embedded in the annular sliding groove, forming a spherical follow-up transmission structure. When the oscillating plate 123 rotates with the spindle 121 and generates eccentric oscillation, the guide ball rod 11 drives the entire worktable 5 to generate multi-angle composite oscillation motion.

[0041] An adjusting wheel 1291 is slidably connected within the annular groove of the adjusting disc 124. An electric push rod 1292 is mounted on one end of the adjusting wheel 1291. The electric push rod 1292 is fixed to one side of the inner wall of the slide block 701. A pull rod 129 is rotatably connected to the edge of the opposite side of the swing disc 123 and the adjusting disc 124 via a pin. The extension and retraction of the electric push rod 1292 drives the adjusting wheel 1291 to slide within the annular groove of the adjusting disc 124, allowing the groove inside the adjusting disc 124 to slide outside the strip plate 126, changing the horizontal position of the adjusting disc 124. Then, the pull rod 129, which is hinged at the edge, pushes and pulls the swing disc 123 to adjust the deflection angle of the swing disc 123. Combined with the transmission action of the main shaft 121, the swing amplitude of the swing disc 123 can be adjusted.

[0042] Working principle:

[0043] The disposable reagent kit to be tested is placed on the bearing area of ​​the workbench 5. Then, the handle 902 at the end of the bidirectional lead screw 901 is rotated to drive the bidirectional lead screw 901 to rotate. This causes the nuts 903 connected by threads on both sides to slide symmetrically along the guide groove of the workbench 5. The nuts 903 simultaneously drive the top slide plate 904 to move horizontally. The slide plate 904 is limited by the bottom T-shaped slider 905 and the T-shaped groove of the workbench 5 to ensure a smooth and non-offset horizontal movement. The distance between the two slide plates 904 can be precisely adjusted according to the size of different reagent kits to accommodate reagent kits of different widths. After the slide plate 904 is adjusted to the correct position, the correction components 10 at the four corners simultaneously complete the all-round correction and limitation of the reagent kit. The L-shaped bracket 101 of the correction component 10 can achieve small-angle adaptive rotation through the rotating shaft 102. With the help of the torsion spring 103 sleeved on the outside of the rotating shaft 102, it always provides elastic reset constraint force for the L-shaped bracket 101, so that the pressure roller 104 at the end fits tightly against the outer wall of the four corners of the reagent kit. The elastic clamping and limiting structure of the four sets of correction components 10 can be used to automatically center and correct the reagent kit that is misplaced or tilted.

[0044] After the reagent kit is positioned and corrected, the automated sample dispensing unit 6 begins the sample dispensing operation. The workstation frame 601 divides the work area into a sample dispensing station 602 and a detection station 603. The workbench 5 is precisely positioned below the sample dispensing station 602. Two sets of electrically operated telescopic rods 604 at the bottom of the workstation frame 601 extend and retract synchronously downwards, driving the automated dispensing unit 605 at the bottom to move downwards as a whole, ensuring that the array of dispensing needles 606 at the bottom are precisely aligned with the various reaction wells of the reagent kit. The automated dispensing unit 605 completes the quantitative aspiration and precise dispensing of reagents and samples.

[0045] After the sample addition process for a single batch of reagent kits is completed, the sliding support assembly 7 is activated, driving the workbench 5 and the top reagent kits to be moved as a whole. The slide 701 adopts a U-shaped structure and is slidably assembled in the two sets of slides 3 of the support platform 2. The multi-stage hydraulic push rod 702 at the bottom of the slide 701 is telescopically driven to provide power for the overall movement. At the same time, the T-shaped protrusion at the top of the support base 8 slides and engages with the T-shaped limiting groove 703 at the bottom of the slide 701 to limit and guide the movement of the slide 701, ensuring that the workbench 5 is moved horizontally and stably.

[0046] The multi-stage hydraulic push rod 702 drives the slide block 701 to slide horizontally along the slide rail 3, moving the worktable 5 from the sample loading station 602 to the testing station 603. When the slide block 701 reaches the preset stroke position, the gear 122 at the end of the main shaft 121 slides into the U-shaped gear frame 13. The teeth of the gear 122 gradually mesh with the bottom teeth of the gear frame 13, and the horizontal linear motion of the slide block 701 is converted into the passive rotational power of the gear 122. During the rotation of the gear 122, the main shaft 121 is driven to rotate coaxially. The main shaft 121 slides with the groove on the inner wall of the adjusting plate 124 through the outer fixed strip plate 126, so that the adjusting plate 124 and the main shaft 121 can be connected. The main shaft 121 transmits driving force to the swing plate 123 through the sliding contact between the clearance groove 125 and the clearance hole 127, so that the adjustment plate 124 and the swing plate 123 rotate synchronously with the main shaft 121. At the same time, the clearance groove 125 is opened on the outer wall of the main shaft 121 and the clearance hole 127 is set in the middle of the swing plate 123. The rotating shaft 128, which is fixed inside the main shaft 121, is rotatably connected to the swing plate 123, so that the swing plate 123 can swing and deflect relative to the main shaft 121. The surface of the swing plate 123 is provided with an annular sliding groove. The bottom ball of the guide rod 11, which is fixed at the bottom center of the worktable 5, is slidably embedded in the annular sliding groove, forming a spherical follow-up transmission structure. When the oscillating plate 123 rotates with the main shaft 121 and generates eccentric oscillation, the guide ball rod 11 drives the entire worktable 5 to generate multi-angle compound oscillation motion, so that the disposable reagent kit placed on it follows the uniform and stable small-amplitude high-frequency or large-amplitude low-frequency oscillation, effectively eliminating the dead corner of reagent mixing. During the oscillation process, the guide rods 704 on both sides of the bottom of the worktable 5 slide through the slide block 701, and together with the spring 705 sleeved on the outside of the guide rod 704, an elastic buffer structure is formed to avoid the generation of bubbles and reagent splashing caused by violent oscillation.

[0047] During operation, the mixing intensity can be adaptively adjusted according to reagent viscosity, sample volume, and mixing requirements. The electric push rod 1292 extends and drives the adjusting wheel 1291 to slide within the annular groove of the adjusting disk 124, allowing the groove inside the adjusting disk 124 to slide outside the strip plate 126, changing the horizontal position of the adjusting disk 124. Then, the edge-hinged pull rod 129 pushes and pulls the swing disk 123, adjusting its deflection angle. Combined with the transmission action of the main shaft 121, this adjusts the swing amplitude of the swing disk 123. The bottom ball of the guide rod 11, fixed at the bottom center of the worktable 5, is slidably connected to the annular groove of the swing disk 123. The multi-angle swing of the swing disk 123 is synchronously transmitted to the worktable 5 through the guide rod 11, causing the worktable 5 and the top reagent kit to perform high-frequency small-amplitude or low-frequency large-amplitude composite oscillation motion.

[0048] The mixing process is completed synchronously with the workbench, eliminating the need for manual transfer and achieving integrated operation of sample addition, transfer, and mixing. Once the workbench 5 is completely transferred to the testing station 603, the gear 122 disengages from the gear frame 13, the mixing action automatically stops, and the subsequent testing process begins.

Claims

1. An automatic sample addition and mixing device for a test kit, characterized in that, include: A frame (1) is provided, on which a support platform (2) is fixed. The support platform (2) has two slide rails (3) and a through hole (4). The through hole (4) is located between the two slide rails (3). A workbench (5) is provided on the support platform (2). An automatic sample dispensing component (6) is provided above the workbench (5). The automatic sample dispensing component (6) is installed on the support platform (2). A sliding support component (7) is slidably installed at the bottom of the workbench (5). The sliding support component (7) slides through the two slide rails (3). Two support seats (8) are slidably installed at the bottom of the sliding support component (7). The support seats (8) are fixed to the machine. At the bottom of the frame (1), an adjustment component (9) is installed through the inside of the workbench (5). Correction components (10) are installed at the four corners of the adjustment component (9). A guide ball rod (11) is fixed at the center of the bottom of the workbench (5). The guide ball rod (11) is installed through the through hole (4). The bottom end of the guide ball rod (11) is connected to a mixing component (12). The mixing component (12) is installed inside the sliding support component (7). A toothed frame (13) is fixed on one side of the bottom of the support platform (2). One end of the mixing component (12) passes through the sliding support component (7) and meshes with the inside of the toothed frame (13).

2. The automatic sample addition and mixing device for a test kit according to claim 1, characterized in that, The automatic sample dispensing assembly (6) includes a workstation frame (601), which is fixed on a support platform (2). The workstation frame (601) has a sample dispensing station (602) and a testing station (603) on its front and rear sides respectively. Two electric telescopic rods (604) are fixed in the sample dispensing station (602). An automatic liquid dispensing device (605) is fixed at the bottom of the two electric telescopic rods (604). Several sample dispensing needles (606) are provided at the bottom of the automatic liquid dispensing device (605), and the sample dispensing needles (606) are located above the workbench (5).

3. The automatic sample addition and mixing device for a test kit according to claim 1, characterized in that, The sliding support assembly (7) includes a slide (701), which is U-shaped and slides through two slides (3). The extended part at the bottom of the slide (701) is fixed with a multi-stage hydraulic push rod (702). The other end of the multi-stage hydraulic push rod (702) is fixed in the frame (1). T-shaped limiting grooves (703) are provided on both sides of the bottom of the slide (701). The T-shaped protrusion at the top of the support base (8) slides in the limiting groove (703).

4. The automatic sample addition and mixing device for a test kit according to claim 3, characterized in that, Two guide rods (704) slide through the slide (701). The guide rods (704) are fixed on both sides of the bottom of the worktable (5). Springs (705) are respectively sleeved on both sides of the outside of the guide rods (704). The springs (705) are fixed between the slide (701) and the bottom of the worktable (5).

5. The automatic sample addition and mixing device for a test kit according to claim 1, characterized in that, The adjustment assembly (9) includes a two-way lead screw (901), the two ends of which are rotated through the worktable (5) via bushings and are fixed with a handle (902). Nuts (903) are threadedly connected to the two sides of the outside of the two-way lead screw (901). The nuts (903) are slidably connected in the guide groove opened on the worktable (5). A slide plate (904) is fixed to the top of the nut (903). T-shaped sliders (905) are fixed to the two sides of the bottom of the slide plate (904). The sliders (905) are slidably connected in the T-shaped groove opened on the worktable (5).

6. The automatic sample addition and mixing device for a test kit according to claim 5, characterized in that, The correction assembly (10) includes an L-shaped bracket (101), with a rotating shaft (102) fixed at the right-angle end of the L-shaped bracket (101). The bottom end of the rotating shaft (102) is rotatably connected to the placement groove opened at the end of the slide plate (904) through a bushing. A torsion spring (103) is sleeved on the outside of the rotating shaft (102). The two ends of the torsion spring (103) are fixed to the outside of the rotating shaft (102) and the bottom of the placement groove at the end of the slide plate (904). Pressure rollers (104) are installed at the two ends of the L-shaped bracket (101).

7. The automatic sample addition and mixing device for a test kit according to claim 4, characterized in that, The mixing assembly (12) includes a main shaft (121). Both ends of the main shaft (121) are rotatably connected to the inside of the slide (701) through bushings. One end of the main shaft (121) passes through the slide (701) and is fixed with a gear (122). The gear (122) is located inside the gear frame (13). The gear frame (13) is U-shaped and has several tooth blocks at the bottom of its inner wall. The bottom of the gear (122) corresponds to the position of the tooth blocks, and the gear (122) is not meshed with the tooth blocks in the current state.

8. The automatic sample addition and mixing device for a test kit according to claim 7, characterized in that, The main shaft (121) is externally fitted with a slidable swing plate (123) and an adjusting plate (124). The swing plate (123) and adjusting plate (124) have annular grooves on their exteriors. The ball at the bottom of the guide rod (11) is slidably connected within the annular groove of the swing plate (123). The main shaft (121) has an external clearance groove (125), and the swing plate (123) has a strip-shaped clearance hole (127) in the middle. The clearance hole (127) contacts the clearance groove (125). A rotating shaft (128) is fixedly inserted through the main shaft (121) at a position corresponding to the clearance groove (125). The two ends of the rotating shaft (128) are sleeved and rotate inside the swing plate (123). A strip plate (126) is fixed outside the main shaft (121). The groove on the inner wall of the adjusting plate (124) slides outside the strip plate (126). An adjusting wheel (1291) is slidably connected in the annular groove of the adjusting plate (124). An electric push rod (1292) is installed at one end of the adjusting wheel (1291). The electric push rod (1292) is fixed on one side of the inner wall of the slide (701). A pull rod (129) is rotatably connected to the edge of the opposite surface of the swing plate (123) and the adjusting plate (124) through a pin.

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