A pathological section staining kit

CN122561417APending Publication Date: 2026-08-14NANJING JICHU BIOMEDICAL TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-06-08
Publication Date
2026-08-14

AI Technical Summary

Technical Problem

[0005]本发明的目的在于提供一种病理切片显色试剂盒,旨在解决现有的病理切片免疫荧光显色试剂盒在实际运用中存在因未设置试剂管压入后的锁定结构,导致弹簧会立即将试剂管弹回,使得多个试剂管无法同时维持在待检测或待孵育的工作位置,操作人员必须用手持续按住已放入的试剂管才能继续放置其他试剂管,操作不够便利的技术问题

Benefits of technology

[0014]本发明的一种病理切片显色试剂盒,包括盒体、隔板、多个弹性复位组件和锁定机构,当所述试剂管被向下按压至预设位置时,所述压紧弹簧持续推动所述滑动块,使所述防滑垫紧密抵压于所述试剂管外壁,依靠静摩擦力克服所述弹性复位组件的向上弹力,将所述试剂管保持于压入状态。由于每个所述放置孔均独立配置该机构,操作人员放入第一个所述试剂管并按压到位后,无需用手持续按住,所述试剂管即可自动维持在低位状态。随后可依次对后续所述试剂管进行相同的锁紧操作,使所有的所述试剂管能够同时稳定地保持在待检测或待孵育的工作位置,从而彻底解决了因无锁定结构导致的操作不便问题。

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Abstract

This invention relates to the field of pharmaceutical testing technology, specifically to a pathological section chromogenic reagent kit. The kit includes a housing, a partition, multiple elastic reset components, and a locking mechanism. When a reagent tube is pressed downwards to a preset position, a compression spring continuously pushes a sliding block, causing an anti-slip pad to press tightly against the outer wall of the reagent tube. Static friction overcomes the upward force of the elastic reset components, holding the reagent tube in the pressed-in state. Since each placement hole is independently equipped with this mechanism, after the operator inserts the first reagent tube and presses it into place, there is no need to continuously press it down by hand; the reagent tube automatically maintains its low position. Subsequently, the same locking operation can be performed on subsequent reagent tubes, ensuring that all reagent tubes are simultaneously and stably held in the working position for testing or incubation, thus completely solving the operational inconvenience caused by the lack of a locking structure.
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Description

Technical Field

[0001] This invention relates to the field of medical testing technology, and in particular to a pathological section chromogenic reagent kit. Background Technology

[0002] Immunoassay technology boasts advantages such as high specificity, high sensitivity, and practicality, making it suitable for measuring bioactive compounds in very low concentrations, including proteins, hormones, drugs, and microorganisms. Immunofluorescence analysis systems, by detecting the fluorescence excited by a laser on a strip, can simultaneously and quantitatively detect single or multiple markers at pg / ml levels.

[0003] A pathological slide immunofluorescence colorimetric reagent kit is disclosed in patent document CN218464317U, relating to the field of medical testing technology. This invention includes a box body and a partition located inside the box body. The partition has multiple placement holes, each containing a reagent tube. Multiple springs are installed at the bottom of the partition, each spring sleeved around the reagent tube. An annular plate is attached to one end of each spring, engaging with the bottom of the reagent tube to support its bottom. This design utilizes the annular plate, which, under the elastic action of the springs, returns to its original position. The returned annular plate then slides the reagent tube through the placement holes, allowing one end of the tube to slide out of the box body. This facilitates quick and easy removal of the reagent tube during use, making its operation more convenient.

[0004] However, existing pathological slide immunofluorescence colorimetric kits lack a locking mechanism after the reagent tubes are inserted, causing the spring to immediately spring back the reagent tubes. This makes it impossible for multiple reagent tubes to be kept in the working position for testing or incubation at the same time. Operators must hold down the inserted reagent tubes with their hands to insert other reagent tubes, which is not convenient. Summary of the Invention

[0005] The purpose of this invention is to provide a pathological slide chromogenic kit, which aims to solve the technical problem that existing pathological slide immunofluorescence chromogenic kits have in practical applications. Due to the lack of a locking structure after the reagent tube is pressed in, the spring will immediately spring back the reagent tube, making it impossible for multiple reagent tubes to be kept in the working position for testing or incubation at the same time. Operators must hold down the inserted reagent tube with their hands to continue to insert other reagent tubes, which is not convenient to operate.

[0006] To achieve the above objectives, the present invention provides a pathological slide chromogenic reagent kit, comprising a box body, a partition, multiple elastic reset components and a locking mechanism. The partition is disposed inside the box body, and multiple placement holes are provided on the partition. A reagent tube is slidably disposed inside each placement hole. Multiple elastic reset components are also disposed at the bottom of the partition, each elastic reset component corresponding to one of the placement holes, and the elastic reset components abut against the bottom of the reagent tube. The locking mechanism includes multiple sliding blocks, multiple compression springs, multiple anti-slip pads, and multiple operating protrusions. Each placement hole has a sliding cavity on its side, and a sliding block is slidably disposed inside each sliding cavity. An anti-slip pad is fixedly disposed on the side of each sliding block facing the corresponding placement hole, and a compression spring is disposed on the side of each sliding block away from the corresponding placement hole. The end of the compression spring away from the corresponding sliding block abuts against the inner end wall of the corresponding sliding cavity. A sliding groove is connected to the top of each sliding cavity, and an operating protrusion is fixedly disposed on the top of each sliding block. The operating protrusion extends upward from the sliding groove and extends above the upper surface of the partition.

[0007] Each of the sliding cavities has a limiting groove on both sides inside, and each of the sliding blocks has a limiting block on both sides, with the limiting block slidably connected to the limiting groove.

[0008] Each of the compression springs is provided with a first abutting ring and a second abutting ring at both ends. The first abutting ring abuts against the end face of the sliding block, and the second abutting ring abuts against the inner end wall of the sliding cavity.

[0009] Each of the operating protrusions has an operating part at one end of the upper surface of the partition, and the upper surface of each operating part is provided with anti-slip texture.

[0010] The pathological slide staining kit further includes an unlocking component, which includes a pressing rod and multiple pushing rods. A mounting groove is provided on the side wall of the box body. The pressing rod is mounted inside the mounting groove via a mounting spring. A pushing groove is provided through the mounting groove facing the inside of the box body. Multiple pushing rods are evenly arranged on the side of the pressing rod facing the inside of the box body. The pushing rods are located on the side of the operating part facing the corresponding placement hole. The operating end of the pressing rod passes through the mounting groove and extends to the outside of the box body.

[0011] The mounting spring is provided with a third abutment ring and a fourth abutment ring at its two ends, respectively. The third abutment ring abuts against the end face of the pressing rod, and the fourth abutment ring abuts against the inner end wall of the mounting groove.

[0012] The outer wall of the box is provided with a mounting protrusion, which is located outside the operating end of the pressing rod. A protective cover is threaded to the mounting protrusion, and the outer wall of the protective cover is provided with anti-slip texture.

[0013] The box body consists of a lower box body and an upper cover. The lower box body is a rectangular box structure with an open top. The partition is fixedly installed inside the lower box body. One side of the upper cover is hinged to the top side of the lower box body. Anti-slip pads are provided at the four bottom corners of the lower box body.

[0014] This invention discloses a pathological section chromogenic reagent kit, comprising a housing, a partition, multiple elastic reset components, and a locking mechanism. When the reagent tube is pressed downward to a preset position, the compression spring continuously pushes the sliding block, causing the anti-slip pad to press tightly against the outer wall of the reagent tube. Static friction overcomes the upward elastic force of the elastic reset components, holding the reagent tube in the pressed-in state. Since each placement hole is independently equipped with this mechanism, after the operator inserts the first reagent tube and presses it into place, the reagent tube automatically maintains its low position without requiring continuous manual pressing. Subsequently, the same locking operation can be performed on subsequent reagent tubes, ensuring that all reagent tubes are simultaneously and stably held in the working position for detection or incubation, thus completely solving the operational inconvenience caused by the lack of a locking structure. Attached Figure Description

[0015] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 This is a schematic diagram of the pathological section staining kit according to the first embodiment of the present invention.

[0017] Figure 2 This is a partial structural schematic diagram of the pathological section staining kit in the first embodiment of the present invention.

[0018] Figure 3 This invention provides Figure 2 A magnified view of the local structure at point A.

[0019] Figure 4 This is a schematic diagram of the pathological section staining kit according to the second embodiment of the present invention.

[0020] Figure 5This is a schematic diagram of the unlocking component in the second embodiment of the present invention.

[0021] Figure 6 This invention provides Figure 5 A magnified view of the local structure at point B.

[0022] 101-Partition, 102-Elastic reset assembly, 103-Sliding block, 104-Compression spring, 105-Anti-slip pad, 106-Operating protrusion, 107-Placement hole, 108-Reagent tube, 109-Lower box body, 110-Top cover, 111-Anti-slip pad foot, 112-Sliding cavity, 113-Sliding groove, 114-Limiting groove, 115-Limiting block, 116-First abutting ring, 117-Second abutting ring, 118-Operating part, 119-Anti-slip texture, 201-Pressing rod, 202-Push rod, 203-Mounting groove, 204-Mounting spring, 205-Pushing groove, 206-Third abutting ring, 207-Fourth abutting ring. Detailed Implementation

[0023] Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain the present invention, and should not be construed as limiting the present invention.

[0024] First embodiment: Please see Figures 1 to 3 ,in Figure 1 This is a schematic diagram of the pathological section staining kit of the first embodiment. Figure 2 This is a partial structural schematic diagram of the pathological section staining kit in the first embodiment. Figure 3 yes Figure 2 A magnified view of the local structure at point A.

[0025] This invention provides a pathological section chromogenic reagent kit, comprising a box body, a partition 101, multiple elastic reset components 102, and a locking mechanism. The locking mechanism includes multiple sliding blocks 103, multiple compression springs 104, multiple anti-slip pads 105, and multiple operating protrusions 106. This solution addresses the problem in practical applications of existing pathological section immunofluorescence chromogenic reagent kits where the lack of a locking structure after the reagent tubes 108 are inserted causes the springs to immediately spring back the tubes, preventing multiple tubes 108 from being simultaneously maintained in the detection or incubation position. Operators must manually hold down an already inserted tube 108 to place other tubes, resulting in inconvenient operation. Therefore, the aforementioned solution can be applied to the structure of the pathological section chromogenic reagent kit.

[0026] In this specific embodiment, the box body is provided with a partition 101 inside. The partition 101 has multiple placement holes 107, and a reagent tube 108 is slidably disposed inside each placement hole 107. The bottom of the partition 101 is also provided with multiple elastic reset components 102, each elastic reset component corresponding to one placement hole 107. The elastic reset component 102 abuts against the bottom of the reagent tube 108. The box body is composed of a lower box body 109 and an upper cover 110. The lower box body 109 has a rectangular box structure with an open top. The partition 101 is fixedly disposed inside the lower box body 109. One side of the upper cover 110 is hinged to one side of the top of the lower box body 109. Anti-slip pads 111 are provided at the four bottom corners of the lower box body 109.

[0027] In this embodiment, the lower box 109 and the upper cover 110 are hinged to form an openable and closable integrated structure, which provides physical protection and a light-proof environment for the internal reagent tube 108; the anti-slip feet 111 are provided at the four bottom corners of the lower box 109 to increase the friction between the box and the work surface.

[0028] Each of the placement holes 107 has a sliding cavity 112 on its side, and a sliding block 103 is slidably disposed inside each of the sliding cavities 112. An anti-slip pad 105 is fixedly disposed on the side of each sliding block 103 facing the corresponding placement hole 107, and a compression spring 104 is disposed on the side of each sliding block 103 away from the corresponding placement hole 107. The end of the compression spring 104 away from the corresponding sliding block 103 abuts against the inner end wall of the corresponding sliding cavity 112. A sliding groove 113 is connected to the top of each sliding cavity 112, and an operating protrusion 106 is fixedly disposed on the top of each sliding block 103. The operating protrusion 106 extends upward from the sliding groove 113 and extends above the upper surface of the partition 101.

[0029] In this embodiment, when the reagent tube 108 is pressed down to the preset working position, the compression spring 104 pushes the sliding block 103 to move closer to the reagent tube 108, so that the anti-slip pad 105 presses against the outer wall of the reagent tube 108. The static friction force overcomes the upward elastic force of the elastic reset component 102, thereby keeping the reagent tube 108 in the pressed-in state. When it is necessary to remove the reagent tube 108, the sliding block 103 is moved away from the reagent tube 108 by moving the operating protrusion 106. The anti-slip pad 105 disengages from the outer wall of the reagent tube 108, and the elastic reset component 102 can then pop the reagent tube 108 upward.

[0030] Secondly, each of the sliding cavities 112 has a limiting groove 114 on both sides inside, and each of the sliding blocks 103 has a limiting block 115 on both sides, with the limiting block 115 slidably connected to the limiting groove 114.

[0031] In this embodiment, the limiting block 115 and the limiting groove 114 make the structure more stable when the sliding block 103 slides inside the sliding cavity 112.

[0032] Meanwhile, each of the compression springs 104 is provided with a first abutment ring 116 and a second abutment ring 117 at both ends. The first abutment ring 116 abuts against the end face of the sliding block 103, and the second abutment ring 117 abuts against the inner end wall of the sliding cavity 112.

[0033] In this embodiment, the first abutment ring 116 and the second abutment ring 117 are used to uniformly transmit the elastic force of the compression spring 104 to the end face of the sliding block 103 and the inner end wall of the sliding cavity 112.

[0034] In addition, each of the operating protrusions 106 is provided with an operating part 118 at one end of the upper surface of the partition 101, and the upper surface of each operating part 118 is provided with anti-slip texture 119.

[0035] In this embodiment, the operating part 118 is used to provide a force surface when the finger flicks the operating protrusion 106, and the anti-slip texture 119 is used to increase the coefficient of friction between the finger and the operating part 118 to prevent slippage due to wet hands or reagents, and to ensure that a single reagent tube 108 can be accurately unlocked.

[0036] When using the pathological section chromogenic reagent kit of this embodiment, firstly, insert multiple reagent tubes 108 containing samples and reagents into the corresponding placement holes 107 in sequence and press them down to the preset working position. Each reagent tube 108 is automatically locked by the corresponding anti-slip pad 105 under the push of the compression spring 104, and can be stably held in place without continuous hand pressure. After all reagent tubes 108 are placed, the entire reagent kit can be transferred to an incubation or detection device for operation. When it is necessary to remove a reagent tube 108, use your finger to move the corresponding operating part 118 of the reagent tube 108, causing the sliding block 103 to retract and release the lock. The elastic reset component 102 automatically pops the reagent tube 108 upward, and the tube removal operation can be completed with one hand. After use, close the top cover 110, and the anti-slip pad feet 111 ensure that the reagent kit is placed stably on the table. This kit uses a locking mechanism to simultaneously lock and hold multiple reagent tubes 108, solving the problem in existing technologies where the reagent tubes 108 cannot be placed sequentially due to the lack of a locking structure, thus significantly improving the efficiency and convenience of batch operations in immunofluorescence staining experiments on pathological sections.

[0037] Second embodiment: Based on the first embodiment, please refer to Figures 4 to 6 , Figure 4 This is a schematic diagram of the pathological section staining kit of the second embodiment. Figure 5 This is a schematic diagram of the unlocking component in the second embodiment. Figure 6 yes Figure 5 A magnified view of the local structure at point B.

[0038] The present invention provides a pathological slide staining kit, which also includes an unlocking component, the unlocking component including a pressing rod 201 and a plurality of pushing rods 202.

[0039] In this specific embodiment, a mounting groove 203 is provided on the side wall of the box body. The pressing rod 201 is mounted inside the mounting groove 203 by a mounting spring 204. A pushing groove 205 is provided through the side of the mounting groove 203 facing the inside of the box body. A plurality of pushing rods 202 are evenly arranged on the side of the pressing rod 201 facing the inside of the box body. The pushing rods 202 are located on the side of the operating part 118 facing the corresponding placement hole 107. The operating end of the pressing rod 201 passes through the mounting groove 203 and extends to the outside of the box body.

[0040] In this embodiment, when multiple reagent tubes 108 need to be unlocked in batches, the operator presses the operating end of the pressing rod 201. The pressing rod 201 overcomes the elastic force of the mounting spring 204 and moves into the box, driving multiple pushing rods 202 to move synchronously towards the operating part 118. Each pushing rod 202 pushes the corresponding operating part 118, causing each sliding block 103 to move synchronously away from the corresponding placement hole 107, thereby simultaneously releasing the locking state of multiple reagent tubes 108. The unlocking component realizes the one-time batch unlocking of multiple reagent tubes 108 without having to manually move the operating part 118 one by one, which significantly improves the efficiency of batch removal of reagent tubes 108.

[0041] The mounting spring 204 is provided with a third abutment ring 206 and a fourth abutment ring 207 at its two ends. The third abutment ring 206 abuts against the end face of the pressing rod 201, and the fourth abutment ring 207 abuts against the inner end wall of the mounting groove 203.

[0042] In this embodiment, the third abutment ring 206 and the fourth abutment ring 207 are used to uniformly transmit the elastic force of the mounting spring 204 to the end face of the pressing rod 201 and the inner end wall of the mounting groove 203.

[0043] When using the pathological section chromogenic reagent kit of this embodiment, if multiple reagent tubes 108 need to be removed simultaneously for testing or replacement, the operator presses the operating end of the pressing rod 201 on the side wall of the box with their finger. The pressing rod 201 moves inward into the box, and multiple pushing rods 202 simultaneously push each operating part 118, causing all sliding blocks 103 to move away from the reagent tubes 108 at the same time. The anti-slip pad 105 disengages from the outer wall of the reagent tubes 108, and each reagent tube 108 pops upward synchronously a distance under the action of the elastic reset component 102, allowing the operator to remove multiple reagent tubes 108 at once. When only a single reagent tube 108 needs to be removed, the corresponding operating part 118 can be directly moved to unlock it individually without using the pressing rod 201. The two unlocking methods do not interfere with each other and can be used selectively. The unlocking component retains the original single unlocking function and adds a batch unlocking function, which not only meets the flexibility requirements of daily single tube removal but also achieves high efficiency in batch operations, further improving the ease of operation of the pathological section chromogenic reagent kit.

[0044] The above description discloses only one preferred embodiment of the present invention, and should not be construed as limiting the scope of the present invention. Those skilled in the art will understand that all or part of the processes of the above embodiments can be implemented, and equivalent changes made in accordance with the claims of the present invention are still within the scope of the invention.

Claims

1. A pathological slide staining kit, comprising a box body, a partition, and multiple elastic reset components, wherein the partition is disposed inside the box body, and multiple placement holes are formed on the partition, a reagent tube is slidably disposed inside each placement hole, and multiple elastic reset components are also disposed at the bottom of the partition, each elastic reset component corresponding to one of the placement holes, and the elastic reset components abut against the bottom of the reagent tube, characterized in that, It also includes locking mechanisms; The locking mechanism includes multiple sliding blocks, multiple compression springs, multiple anti-slip pads, and multiple operating protrusions. Each placement hole has a sliding cavity on its side, and a sliding block is slidably disposed inside each sliding cavity. An anti-slip pad is fixedly disposed on the side of each sliding block facing the corresponding placement hole, and a compression spring is disposed on the side of each sliding block away from the corresponding placement hole. The end of the compression spring away from the corresponding sliding block abuts against the inner end wall of the corresponding sliding cavity. A sliding groove is connected to the top of each sliding cavity, and an operating protrusion is fixedly disposed on the top of each sliding block. The operating protrusion extends upward from the sliding groove and extends above the upper surface of the partition.

2. The pathological section staining kit as described in claim 1, characterized in that, Each of the sliding cavities has a limiting groove on both sides inside, and each of the sliding blocks has a limiting block on both sides, with the limiting block slidably connected to the limiting groove.

3. The pathological section staining kit as described in claim 1, characterized in that, Each of the compression springs is provided with a first abutment ring and a second abutment ring at both ends. The first abutment ring abuts against the end face of the sliding block, and the second abutment ring abuts against the inner end wall of the sliding cavity.

4. The pathological section staining kit as described in claim 1, characterized in that, Each of the operating protrusions has an operating part at one end of the upper surface of the partition, and the upper surface of each operating part is provided with anti-slip texture.

5. The pathological section staining kit as described in claim 4, characterized in that, The pathological slide staining kit also includes an unlocking component, which includes a pressing rod and multiple pushing rods. A mounting groove is provided on the side wall of the box body. The pressing rod is mounted inside the mounting groove via a mounting spring. A pushing groove is provided through the mounting groove on the side facing the inside of the box body. Multiple pushing rods are evenly arranged on the side of the pressing rod facing the inside of the box body. The pushing rods are located on the side of the operating part facing the corresponding placement hole. The operating end of the pressing rod passes through the mounting groove and extends to the outside of the box body.

6. The pathological section staining kit as described in claim 5, characterized in that, The mounting spring is provided with a third abutment ring and a fourth abutment ring at its two ends respectively. The third abutment ring abuts against the end face of the pressing rod, and the fourth abutment ring abuts against the inner end wall of the mounting groove.

7. The pathological section staining kit as described in claim 6, characterized in that, The outer wall of the box is also provided with a mounting protrusion ring, which is located outside the operating end of the pressing rod. A protective cover is threaded to the mounting protrusion ring, and the outer wall of the protective cover is provided with anti-slip texture.

8. The pathological section staining kit as described in claim 1, characterized in that, The box consists of a lower box and an upper cover. The lower box has a rectangular box structure with an opening at the top. The partition is fixedly installed inside the lower box. One side of the upper cover is hinged to the top side of the lower box. Anti-slip pads are provided at the four bottom corners of the lower box.

Citation Information

Patent Citations

  • Pathological section immunofluorescence developing kit

    CN218464317U