A medical antibacterial zirconia-titanium carbide ceramic material and its preparation method

Abstract

This invention belongs to the field of medical ceramic materials technology, specifically a medical antibacterial zirconia-titanium carbide ceramic material and its preparation method. Zirconia nanoparticles, titanium carbide nanoparticles, rare earth oxide powders, and polyvinyl alcohol solution are uniformly mixed using a ball mill. The mixed material is then pressed into a green body, which is dried and then hot-pressed and sintered under an argon atmosphere at a temperature of 1600-1700℃, a holding time of 2-5 hours, and a sintering pressure of 20-50 MPa. Subsequently, a low-temperature oxidation treatment is performed to obtain the antibacterial zirconia-titanium carbide ceramic material. The antibacterial zirconia-titanium carbide ceramic material prepared by this invention has high compressive strength and hardness, excellent antibacterial properties, and the antibacterial layer can regenerate and achieve self-repair function after low-temperature re-oxidation treatment. This antibacterial zirconia-titanium carbide ceramic material can be used to manufacture high-precision surgical instruments, effectively reducing postoperative infection, accelerating wound healing, and improving surgical efficiency and instrument life.

Description

Technical Field

[0001] This invention belongs to the field of medical ceramic materials technology, specifically a medical antibacterial zirconia-titanium carbide ceramic material and its preparation method. Background Technology

[0002] Traditional surgical scalpels are mostly made of carbon steel or stainless steel. While these materials can meet certain cutting requirements during surgery, they have several shortcomings. First, carbon steel scalpels are prone to rust, affecting their biocompatibility and lifespan. Second, carbon steel has limited sharpness and hardness, making it difficult to maintain cutting performance over a long period, and it is susceptible to corrosion and wear, affecting its lifespan. Furthermore, postoperative wounds often experience infection and inflammation, which negatively impacts patient recovery.

[0003] Zirconia, as an excellent ceramic material, possesses high chemical stability, hardness, wear resistance, and good biocompatibility, thus it is widely used in medical fields such as dentistry and bone and joint replacement. Nano-zirconia surgical scalpels not only avoid blade breakage and fracture when cutting skin tissue but also exhibit superior performance. Compared to traditional carbon steel scalpels, zirconia scalpels accelerate postoperative wound healing and reduce infection and inflammatory responses. Furthermore, zirconia scalpels produce smoother, cleaner incision edges and smaller scars, demonstrating promising clinical application prospects.

[0004] However, zirconia alone still suffers from insufficient antibacterial properties in surgical scalpel applications, affecting its overall performance and postoperative recovery to some extent. Furthermore, most composite materials in existing technologies lack self-healing capabilities; when the antibacterial layer wears or is damaged during use, its antibacterial effect gradually weakens or even disappears. Developing a medical surgical scalpel material that provides excellent antibacterial properties and can self-repair after the antibacterial layer wears off remains a pressing technical challenge. Summary of the Invention

[0005] To address the above problems, this invention provides a medical antibacterial zirconia-titanium carbide ceramic material and its preparation method. By introducing TiC to enhance the material's hardness, wear resistance, and chemical stability, and by forming TiO2 on the material surface through low-temperature oxidation treatment, the strength and structural stability of the material are improved by adding rare earth oxides, and the antibacterial properties of TiO2 under visible light are enhanced. This effectively improves the overall performance of the zirconia-based ceramic material. Surgical instruments made from this medical antibacterial zirconia-titanium carbide ceramic material are expected to effectively reduce the risk of postoperative infection, accelerate wound healing, and improve surgical efficiency and the lifespan of surgical instruments.

[0006] This invention is specifically achieved through the following technical solution: a method for preparing a medical antibacterial zirconia-titanium carbide ceramic material according to this invention, characterized by comprising the following steps: (1) Zirconia nanopowder, titanium carbide nanopowder, rare earth oxide powder and polyvinyl alcohol solution are mixed evenly using a ball mill; wherein, the mass percentages of zirconia nanopowder, titanium carbide nanopowder and rare earth oxide powder to the total mass of zirconia nanopowder, titanium carbide nanopowder and rare earth oxide powder are 60~80wt%, 15~37wt% and 1~5wt%, respectively; (2) Press the material after mixing in step (1) into a blank, and put the blank into a drying oven to dry it. (3) The blank dried in step (2) is hot-pressed and sintered under an argon atmosphere at a sintering temperature of 1600~1700℃, a holding time of 2~5h, and a sintering pressure of 20~50MPa; then it is subjected to low-temperature oxidation treatment to obtain antibacterial zirconium oxide-titanium carbide ceramic material.

[0007] In the aforementioned method for preparing medical antibacterial zirconia-titanium carbide ceramic materials, the particle size of the zirconia nanopowder in step (1) is ≤100 nm, the zirconia is monoclinic zirconia, the particle size of the titanium carbide nanopowder is ≤100 nm, the rare earth oxide is selected from at least one of cerium oxide, lanthanum oxide, and yttrium oxide, and the particle size of the rare earth oxide is ≤0.074 mm; the mass percentage of the polyvinyl alcohol solution is 2~5%, and its added mass accounts for 2~6% of the total mass of zirconia nanopowder, titanium carbide nanopowder and rare earth oxide powder.

[0008] In the aforementioned preparation method of medical antibacterial zirconia-titanium carbide ceramic material, in step (1), zirconia balls are used for grinding, the ball-to-material ratio is 3:1, and the ball mill speed is 300~500r / min.

[0009] In the aforementioned preparation method of medical antibacterial zirconia-titanium carbide ceramic material, the molding pressure during step (2) is 150~200MPa and the holding time is 15s; the blank is placed in a drying oven and dried at 100~120℃ for 12~24h.

[0010] In the aforementioned method for preparing medical antibacterial zirconia-titanium carbide ceramic materials, the temperature of the low-temperature oxidation treatment in step (3) is 400~500℃, preferably 450-500℃, and the treatment time is 3~5h.

[0011] The aforementioned method for preparing medical antibacterial zirconia-titanium carbide ceramic materials involves low-temperature oxidation treatment performed in a muffle furnace under an air atmosphere.

[0012] The aforementioned method for preparing medical antibacterial zirconia-titanium carbide ceramic materials yields antibacterial zirconia-titanium carbide ceramic materials with a compressive strength of 730~850MPa, a Vickers hardness of 1430~1580HV, and an antibacterial rate of 99.1~99.8%.

[0013] The present invention also provides a medical antibacterial zirconia-titanium carbide ceramic material obtained by the aforementioned preparation method. This medical antibacterial zirconia-titanium carbide ceramic material has high compressive strength and hardness, and excellent antibacterial properties. It can be used as a material for medical surgical instruments to manufacture medical scalpels and other instruments, thereby improving the antibacterial properties of the instruments during use.

[0014] Compared with the prior art, the present invention has at least the following advantages: (1) This invention uses zirconium oxide as the matrix and prepares zirconium oxide-titanium carbide ceramic materials by introducing TiC. The introduction of TiC enhances the hardness, wear resistance, and chemical stability of the material. By adding rare earth oxides, rare earth ions (La) are introduced. 3+ or Ce 4+ Doping with rare earth ions (La) 3+ or Ce 4+ Doping with titanium carbide allows it to dissolve into the zirconia lattice, suppressing the zirconia phase transformation during sintering and improving the material's strength and structural stability. Simultaneously, titanium carbide can oxidize at low temperatures to form a TiO2 antibacterial layer, introducing rare earth ions (La). 3+ or Ce 4+ Impurity energy levels or carrier traps can be introduced into the TiO2 lattice, enabling visible light to excite electron-hole pairs and suppress recombination, thereby improving the efficiency of reactive oxygen generation and enhancing the antibacterial properties of TiO2 under visible light. This allows TiO2 to generate hydroxyl radicals with strong oxidizing capabilities under visible light irradiation, thus playing an antibacterial role.

[0015] (2) The zirconia-titanium carbide ceramic material prepared by this invention has an antibacterial rate of 88.50% before low-temperature oxidation treatment. After low-temperature oxidation treatment at 400~500℃ for 3~5 hours, the antibacterial rate can reach more than 99%, demonstrating excellent antibacterial properties. Furthermore, the antibacterial zirconia-titanium carbide ceramic material has high compressive strength and hardness, making it suitable as a medical material for manufacturing medical surgical instruments such as scalpels. During use, the antibacterial layer may wear down and fail due to prolonged and repeated use. By performing low-temperature re-oxidation treatment on surgical instruments (such as scalpels), the TiO2 antibacterial layer can be repaired, achieving self-repair of the antibacterial function of the antibacterial zirconia-titanium carbide ceramic material. This self-repair function effectively overcomes the shortcomings of traditional coating materials, such as easy failure and the need for frequent sterilization. Therefore, this invention, through the combination of zirconia and titanium carbide materials and the doping with rare earth ions, effectively improves the comprehensive performance of zirconia-based ceramic materials, especially in terms of antibacterial properties and durability. In addition, this material has good biocompatibility. When used to manufacture surgical instruments, it can effectively reduce the risk of postoperative infection, accelerate wound healing, improve surgical efficiency and the service life of surgical instruments, and has broad application prospects and social significance. Attached Figure Description

[0016] Figure 1 This is the XRD pattern of the sample obtained after hot pressing and sintering in Example 1.

[0017] Figure 2 This is the XRD pattern of the antibacterial zirconia-titanium carbide ceramic material obtained after low-temperature oxidation treatment in Example 1.

[0018] Figure 3 This is a SEM image of the antibacterial zirconia-titanium carbide ceramic material obtained in Example 1.

[0019] Figure 4 These are photographs of the ceramic materials obtained in Example 1, Comparative Example 1, and Comparative Example 2 after being placed in a constant temperature chamber at 37°C for 18 hours during the antibacterial rate test. Detailed Implementation

[0020] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be clearly and completely described below in conjunction with specific embodiments. Obviously, the described embodiments are only some embodiments of this invention, not all embodiments. Based on the embodiments of this invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this invention.

[0021] The present invention will be described in detail below with reference to specific embodiments. Unless otherwise specified, all conditions in the embodiments are performed under conventional conditions or conditions recommended by the manufacturer. Raw materials and reagents used, unless otherwise specified, are all commercially available products. Unless otherwise specified, the scientific and technical terms and experimental methods in this invention are based on the conventional understanding and existing standard methods of those skilled in the art. It should be understood that the parameters such as temperature and holding time involved in this invention are approximate values ​​and are used for illustrative purposes; those skilled in the art can make reasonable adjustments according to actual needs.

[0022] Example 1: A medical antibacterial zirconia-titanium carbide ceramic material, comprising the following raw materials: 60 wt% monoclinic zirconia nanoparticles (particle size ≤ 100 nm), 37 wt% titanium carbide nanoparticles (particle size ≤ 100 nm), and 3 wt% cerium oxide powder (particle size ≤ 0.074 mm), and its preparation method includes: (1) 60wt% monoclinic zirconia nanopowder, 37wt% titanium carbide nanopowder, 3wt% cerium oxide powder and polyvinyl alcohol solution were mixed evenly using a ball mill; wherein, zirconia balls were used as grinding balls, the ball-to-material ratio was 3:1, the ball mill speed was 300r / min, the mass percentage of polyvinyl alcohol solution was 2%, and its added mass accounted for 4% of the total mass of monoclinic zirconia nanopowder, titanium carbide nanopowder and cerium oxide powder; (2) Press the material after mixing in step (1) into a blank, the molding pressure is 150MPa and the holding time is 15s; put the obtained blank into a drying oven and dry it at 110℃ for 12h. (3) The dried blank from step (2) is placed in a hot pressing sintering furnace and hot pressing is carried out under an argon atmosphere. The sintering temperature is 1700℃, the holding time is 3h, and the sintering pressure is 20MPa. The hot-pressed sample is placed in a muffle furnace and low-temperature oxidation is carried out under an air atmosphere. The low-temperature oxidation temperature is 450℃ and the holding time is 5h. After completion, it is naturally cooled to room temperature to obtain antibacterial zirconium oxide-titanium carbide ceramic material S1.

[0023] Figure 1 The image shows the XRD pattern of the sample obtained after hot pressing and sintering. It can be seen that the phase is mainly composed of c-ZrO2 (cubic zirconia) and TiC, indicating that monoclinic zirconia was transformed into cubic zirconia during the reaction.

[0024] Figure 2 The image shows the XRD pattern of the antibacterial zirconia-titanium carbide ceramic material obtained after low-temperature oxidation treatment. It can be seen that its phases are mainly composed of c-ZrO2, TiC and TiO2, and TiO2 is anatase type.

[0025] Figure 3This is a SEM image of the antibacterial zirconia-titanium carbide ceramic material obtained in this embodiment. It can be seen that ZrO2 and TiC form a tight bond.

[0026] The antibacterial zirconia-titanium carbide ceramic material prepared in this embodiment was subjected to performance tests. The compressive strength test method was performed according to GB / T 5072-2008 standard, and the Vickers hardness test method was performed according to BS EN ISO 14705:2021 standard. The antibacterial rate test method was as follows: Staphylococcus aureus bacterial solution was diluted to 105 CFU / mL with 1 / 500 NB aqueous solution (the liquid obtained by diluting 1 part NB liquid culture medium with 499 parts water) to obtain bacterial solution A. A block sample of antibacterial zirconia-titanium carbide ceramic material obtained in Example 1 (dimensions: length × width × height 1cm × 1cm × 0.5cm) was placed in a disposable petri dish, and 50 μL of bacterial solution A was evenly dropped onto the surface of the block sample as the experimental group. 50 μL of bacterial solution A was dropped into another new disposable petri dish as the blank group. The experimental group and the blank group were placed in a constant temperature incubator at 37℃ and irradiated with visible light for 24 hours. After completion, the bacterial suspension on the surface of the experimental group block samples was eluted with 2 mL of sterile PBS solution, and then the eluent was diluted with 20 mL of sterile PBS solution. An equal volume of sterile PBS solution was added to the bacterial suspension of the blank group for dilution. 100 μL of the diluted bacterial suspension from both the experimental and blank groups was evenly spread onto LB solid medium and incubated at 37°C for 18 h. After incubation, the samples were photographed and the colony count was recorded. The antibacterial rate was calculated as follows: Antibacterial rate = (Number of colonies in the blank group - Number of colonies in the experimental group) ÷ Number of colonies in the blank group × 100%.

[0027] According to the test, the compressive strength of the antibacterial zirconia-titanium carbide ceramic material S1 obtained in this embodiment is 791 MPa, the Vickers hardness is 1554 HV, and the antibacterial rate is 99.75%.

[0028] To verify that the antibacterial zirconia-titanium carbide ceramic material prepared in this invention has self-healing function, antibacterial zirconia-titanium carbide ceramic material S1 (hereinafter referred to as "sample") was prepared according to the method of Example 1. The titanium dioxide layer on the surface of the sample was removed by sandpaper, and its antibacterial rate was tested according to the aforementioned antibacterial rate test method. The worn sample was placed in a muffle furnace and subjected to low-temperature oxidation treatment at 450°C for 4 hours in an air atmosphere. After naturally cooling to room temperature, its antibacterial rate was tested again.

[0029] Test results: The antibacterial rate of the worn sample was 87.51%; after low-temperature oxidation treatment at 450℃, the antibacterial rate of the sample reached 99.46%, which indicates that the antibacterial zirconia-titanium carbide ceramic material prepared can have its antibacterial properties restored after wear by low-temperature oxidation treatment.

[0030] Example 2: A medical-grade antibacterial zirconia-titanium carbide ceramic material comprises the following raw materials: 70 wt% monoclinic zirconia nanoparticles (particle size ≤ 100 nm), 27 wt% titanium carbide nanoparticles (particle size ≤ 100 nm), and 3 wt% lanthanum oxide powder (particle size ≤ 0.074 mm). Its preparation method includes: (1) 70 wt% monoclinic zirconia nanopowder, 27 wt% titanium carbide nanopowder, 3 wt% lanthanum oxide powder and polyvinyl alcohol solution were mixed evenly using a ball mill; wherein, zirconia balls were used for grinding, the ball-to-material ratio was 3:1, the ball mill speed was 350 r / min, the mass percentage of polyvinyl alcohol solution was 4%, and its added mass accounted for 3% of the total mass of monoclinic zirconia nanopowder, titanium carbide nanopowder and lanthanum oxide powder; (2) Press the material after mixing in step (1) into a blank, the molding pressure is 160MPa and the holding time is 15s; put the obtained blank into a drying oven and dry it at 100℃ for 15h. (3) The dried blank from step (2) is placed in a hot pressing sintering furnace and hot pressing is carried out under an argon atmosphere. The sintering temperature is 1650℃, the holding time is 3h, and the sintering pressure is 40MPa. The hot-pressed sample is placed in a muffle furnace and low-temperature oxidation is carried out under an air atmosphere. The low-temperature oxidation temperature is 450℃ and the holding time is 3.5h. After completion, it is naturally cooled to room temperature to obtain antibacterial zirconia-titanium carbide ceramic material S2.

[0031] The antibacterial zirconia-titanium carbide ceramic material obtained in this embodiment has a compressive strength of 738 MPa, a Vickers hardness of 1487 HV, and an antibacterial rate of 99.62%, as tested.

[0032] Example 3: A medical-grade antibacterial zirconia-titanium carbide ceramic material comprises the following raw materials: 80 wt% monoclinic zirconia nanoparticles (particle size ≤ 100 nm), 15 wt% titanium carbide nanoparticles (particle size ≤ 100 nm), and 5 wt% yttrium oxide powder (particle size ≤ 0.074 mm). Its preparation method includes: (1) 80 wt% monoclinic zirconia nanopowder, 15 wt% titanium carbide nanopowder, 5 wt% yttrium oxide powder and polyvinyl alcohol solution were mixed evenly using a ball mill; wherein, zirconia balls were used as grinding balls, the ball-to-material ratio was 3:1, the ball mill speed was 400 r / min, the mass percentage of polyvinyl alcohol solution was 3%, and its added mass accounted for 5% of the total mass of monoclinic zirconia nanopowder, titanium carbide nanopowder and yttrium oxide powder; (2) Press the material after mixing in step (1) into a blank, the molding pressure is 180MPa and the holding time is 15s; put the obtained blank into a drying oven and dry it at 110℃ for 12h. (3) The dried blank from step (2) is placed in a hot pressing sintering furnace and hot pressing is carried out under an argon atmosphere. The sintering temperature is 1700℃, the holding time is 3h, and the sintering pressure is 30MPa. The hot-pressed sample is placed in a muffle furnace and low-temperature oxidation is carried out under an air atmosphere. The low-temperature oxidation temperature is 500℃ and the holding time is 3h. After completion, it is naturally cooled to room temperature to obtain antibacterial zirconium oxide-titanium carbide ceramic material S3.

[0033] The antibacterial zirconia-titanium carbide ceramic material obtained in this embodiment has a compressive strength of 836 MPa, a Vickers hardness of 1435 HV, and an antibacterial rate of 99.17%, as tested.

[0034] Comparative Example 1: According to the raw material ratio and process steps of Example 1, the green body dried in step (2) is subjected to hot pressing and sintering treatment in step (3), and then without low-temperature oxidation treatment, zirconia ceramic material M1 is obtained.

[0035] Tests showed that the zirconia ceramic material M1 obtained in this comparative example has a compressive strength of 774 MPa, a Vickers hardness of 1526 HV, and an antibacterial rate of 88.50%.

[0036] Comparative Example 2: A zirconia ceramic material, comprising: 95 wt% monoclinic zirconia nanopowder (particle size ≤ 100 nm) and 5 wt% cerium oxide powder (particle size ≤ 0.074 mm), without the addition of titanium carbide nanopowder, and prepared by: uniformly mixing 95 wt% monoclinic zirconia nanopowder, 5 wt% cerium oxide powder and polyvinyl alcohol solution using a ball mill, wherein the mass percentage of polyvinyl alcohol solution is 2%, and its added mass accounts for 4% of the total mass of zirconia nanopowder and cerium oxide powder; the remaining operations and process conditions are the same as in Example 1, and the obtained sample is zirconia ceramic material M2.

[0037] Tests showed that the zirconia ceramic material M2 obtained in this comparative example has a compressive strength of 715 MPa, a Vickers hardness of 1154 HV, and an antibacterial rate of 57.06%.

[0038] Following the antibacterial rate testing method described in Example 1, the antibacterial rates of the ceramic materials obtained in Examples 1-3 and Comparative Examples 1-2 were tested respectively. Samples that had been placed in a 37°C constant temperature chamber for 18 hours during the antibacterial rate testing process were photographed. The photographic results are as follows: Figure 4 As shown, it is clear that there are almost no Staphylococcus aureus residues on the surface of the culture medium in Example 1, a small amount of Staphylococcus aureus residues on the surface of the culture medium in Comparative Example 1, and a significantly larger number of Staphylococcus aureus on the surface of the culture medium in Comparative Example 2. This indicates that the antibacterial zirconia-titanium carbide ceramic material prepared by the process of the present invention has excellent antibacterial properties.

[0039] As can be seen from the foregoing examples and comparative examples, the sample of Comparative Example 1, which did not undergo low-temperature oxidation treatment, had compressive strength and Vickers hardness similar to that of Example 1, but its antibacterial rate was significantly lower than that of Example 1. This is because the zirconia-titanium carbide ceramic material did not undergo low-temperature oxidation treatment, and TiO2 was not formed on its surface, resulting in poor antibacterial properties. The ceramic sample of Comparative Example 2, prepared by adding only zirconia and cerium oxide, had compressive strength, Vickers hardness, and antibacterial rate lower than those of Examples 1-3.

[0040] The above description is merely an embodiment of the present invention and is not intended to limit the present invention in any way. The present invention can also have other embodiments based on the above structure and function, which will not be listed hereafter. Therefore, any simple modifications, equivalent changes, and alterations made by those skilled in the art to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.

Claims

1. A method for preparing a medical antibacterial zirconia-titanium carbide ceramic material, characterized in that, Includes the following steps: (1) Zirconia nanopowder, titanium carbide nanopowder, rare earth oxide powder and polyvinyl alcohol solution are mixed evenly using a ball mill; wherein, the mass percentages of zirconia nanopowder, titanium carbide nanopowder and rare earth oxide powder to the total mass of zirconia nanopowder, titanium carbide nanopowder and rare earth oxide powder are 60~80wt%, 15~37wt% and 1~5wt%, respectively; (2) Press the material after mixing in step (1) into a blank, and put the blank into a drying oven to dry it. (3) The blank dried in step (2) is hot-pressed and sintered under an argon atmosphere at a sintering temperature of 1600~1700℃, a holding time of 2~5h, and a sintering pressure of 20~50MPa; then it is subjected to low-temperature oxidation treatment to obtain medical antibacterial zirconium oxide-titanium carbide ceramic material.

2. The preparation method of the medical antibacterial zirconia-titanium carbide ceramic material as described in claim 1, characterized in that, The zirconium oxide nanopowder in step (1) has a particle size ≤100 nm, the zirconium oxide is monoclinic zirconium oxide, the titanium carbide nanopowder has a particle size ≤100 nm, the rare earth oxide is selected from at least one of cerium oxide, lanthanum oxide, and yttrium oxide, and the particle size of the rare earth oxide is ≤0.074 mm; the polyvinyl alcohol solution has a mass percentage of 2~5%, and its added mass accounts for 2~6% of the total mass of zirconium oxide nanopowder, titanium carbide nanopowder and rare earth oxide powder.

3. The preparation method of the medical antibacterial zirconia-titanium carbide ceramic material as described in claim 1, characterized in that, In step (1), zirconia grinding balls are used with a ball-to-material ratio of 3:1 and a ball mill speed of 300~500 r / min.

4. The preparation method of the medical antibacterial zirconia-titanium carbide ceramic material as described in claim 1, characterized in that, In step (2), the molding pressure is 150~200MPa and the holding time is 15s; the blank is placed in a drying oven and dried at 100~120℃ for 12~24h.

5. The preparation method of the medical antibacterial zirconia-titanium carbide ceramic material as described in claim 1, characterized in that, In step (3), the low-temperature oxidation treatment is carried out at a temperature of 400~500℃ for 3~5 hours.

6. The preparation method of the medical antibacterial zirconia-titanium carbide ceramic material as described in claim 1, characterized in that, The low-temperature oxidation process is carried out in a muffle furnace under an air atmosphere.

7. The preparation method of the medical antibacterial zirconia-titanium carbide ceramic material as described in claim 1, characterized in that, The obtained antibacterial zirconia-titanium carbide ceramic material has a compressive strength of 730~850MPa, a Vickers hardness of 1430~1580HV, and an antibacterial rate of 99.1~99.8%.

8. The medical antibacterial zirconia-titanium carbide ceramic material obtained by the preparation method according to any one of claims 1-6.

9. The application of the medical antibacterial zirconia-titanium carbide ceramic material obtained by the preparation method according to any one of claims 1-6 as a material for medical surgical instruments.

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