A repair composition, its preparation method and use in cosmetics

Abstract

The present application belongs to the technical field of cosmetics, and particularly relates to a repairing composition, a preparation method thereof and application thereof in cosmetics. The present application selects four kinds of functional active components, i.e. tetrahydro methyl pyrimidine carboxylic acid, glycyrrhizic acid dipotassium, phytosterol oleate, ceramide NP and phlox root extract, and scientifically compounding the five components in a specific amount ratio range. The physicochemical properties and action mechanisms of the components are different and complementary to each other, and the defects such as single active component, limited action dimension, single efficacy and weak skin care effect are avoided. The five components rely on unique action targets and action pathways to form a multi-level and full-link synergistic system in three core dimensions of skin barrier repair, photodamage protection and whitening, thereby significantly improving the overall skin care performance of the composition.

Description

Technical Field

[0001] This invention belongs to the field of cosmetic technology, and particularly relates to a repair composition, its preparation method, and its application in cosmetics. Background Technology

[0002] The skin barrier is the body's first line of defense against external environmental damage, and its integrity is crucial for maintaining skin health. The "brick wall structure" of the stratum corneum is composed of keratinocytes (bricks) and the intercellular lipid matrix (mortar). The lipid matrix is ​​mainly composed of ceramides, cholesterol, and free fatty acids arranged in a specific ratio to form a layered structure. When the skin is affected by external factors such as ultraviolet radiation, chemical stimulation, excessive cleansing, and environmental pollution, the lipid composition of the stratum corneum becomes imbalanced, and defects and breaks occur in the layered structure. This leads to increased transepidermal water loss (TEWL), dry and sensitive skin, and increased release of inflammatory factors, thereby triggering a series of skin problems.

[0003] Meanwhile, ultraviolet radiation, as a major cause of photoaging, not only directly leads to DNA damage (such as the formation of thymine dimers), but also induces the production of reactive oxygen species (ROS), causing a series of pathological changes such as mitochondrial DNA damage, impaired Langerhans cell function, activation of inflammatory cascades, and excessive melanin synthesis. In existing technologies, cosmetic products targeting skin barrier repair, photoprotection, and whitening typically focus on a single efficacy, or, although containing multiple active ingredients, lack synergistic formulation design.

[0004] Most repair cosmetics currently on the market use a combination of single ceramides or simple moisturizers. While these can improve skin barrier function to some extent, their efficacy in anti-photoaging, DNA protection, and whitening is limited. Whitening products often focus on inhibiting tyrosinase activity or melanin transport, neglecting the fundamental supporting role of barrier repair and photoprotection in achieving whitening effects. Therefore, there is an urgent need to develop a repair composition that can work synergistically across the three dimensions of barrier repair, photoprotection, and whitening. Summary of the Invention

[0005] The purpose of this invention is to overcome the shortcomings of the prior art by providing a repair composition, its preparation method, and its application in cosmetics. The composition, through synergistic effects of its components, simultaneously achieves triple benefits: skin barrier repair, photoprotection (including anti-photoaging and DNA protection), and whitening and brightening, thus improving upon the problems of conventional products having single efficacy and poor repair effects.

[0006] To achieve the above objectives, the technical solution adopted by the present invention includes: In a first aspect, the present invention provides a repair composition comprising the following components in parts by weight: 0.01-3 parts of tetrahydromethylpyrimidine carboxylic acid, 0.00001-2 parts of dipotassium glycyrrhizate, 0.00005-3 parts of phytosterol oleate, 0.0001-3 parts of ceramide NP, and 0.0000005-2 parts of marshmallow root extract.

[0007] Tetrahydromethylpyrimidine carboxylic acid (ectoin) is a natural extreme environmental protection molecule. This molecule is highly hydrophilic and can form a highly ordered "hydration shell" of water molecules around itself. When it approaches the surface of proteins or cell membranes, it is "repelled" to the periphery, while simultaneously pushing a large number of ordered water molecules to the surface of biomolecules, thereby stabilizing the natural conformation of proteins and cell membranes. Based on this mechanism, it plays multiple roles in this composition: first, structural moisturizing; second, anti-inflammatory and immunomodulatory effects, inhibiting UV-induced Langerhans cell damage, reducing the release of inflammatory factors such as IL-6 and TNF-α, and inhibiting the expression of AP-2 protein and ICAM-1; third, DNA protection and anti-photoaging, reducing the formation of photodamage products such as thymine dimers and lowering ROS levels by stabilizing the DNA double helix structure and repairing protein conformation; and fourth, barrier repair, stabilizing the cell membrane phospholipid bilayer and maintaining the orderliness of the lipid matrix in the "brick wall structure" of the stratum corneum.

[0008] The core function of dipotassium glycyrrhizate is to soothe and reduce inflammation. It can inhibit the release of inflammatory mediators in the skin, relieving redness, stinging, and burning sensations caused by ultraviolet radiation, chemical irritation, or allergies. Simultaneously, dipotassium glycyrrhizate can reduce melanin production, resulting in a whitening effect that fades dark spots and brightens the skin tone. Furthermore, it has some moisturizing ability, which can help repair damaged skin barriers and enhance the skin's self-defense capabilities. In this composition, dipotassium glycyrrhizate and tetrahydromethylpyrimidine carboxylic acid form a synergistic effect on the anti-inflammatory level. Both inhibit the inflammatory response through different targets and pathways, enhancing the overall anti-inflammatory effect.

[0009] The molecular backbone of phytosterol oleate is highly similar to cholesterol in human skin, allowing it to embed itself in the layered structure of intercellular lipids in the stratum corneum, partially replacing or supplementing cholesterol. The oleic acid chains form excellent hydrophobic interactions with the fatty acid components. Its core function is "structural repair," directly supplementing the deficiency of sterol components in the lipid matrix at the lipid composition level, restoring the orderly arrangement of layered lipids, and reducing TEWL (transient endothelial wound healing). Simultaneously, phytosterol oleate exhibits significant anti-inflammatory activity, inhibiting phospholipase A2 activity, reducing the production of pro-inflammatory mediators such as PGE2, downregulating the NF-κB signaling pathway, and decreasing the expression of inflammatory factors such as IL-1β and IL-6. Furthermore, it can promote the proliferation of keratinocytes and fibroblasts, accelerating the skin's self-repair process.

[0010] Ceramide NP is the most abundant ceramide subtype in the stratum corneum lipid matrix (accounting for approximately 50% of the lipid matrix) and is a key component determining the integrity of the lamellar structure. Its molecular structure consists of a long sphingosine base linked to a non-hydroxy fatty acid chain, allowing it to precisely embed within the lamellar arrangement of intercellular lipids in the stratum corneum. Through amide bonds and hydroxyl groups, it forms a lateral hydrogen bond network with adjacent molecules, maintaining the stability of the lamellar structure. Exogenous supplementation of ceramide NP can effectively repair defects in the lipid lamellar structure. Its moisturizing mechanism differs from that of water-absorbing moisturizers; instead, it prevents moisture loss by repairing the integrity of the lipid barrier, resulting in a longer-lasting effect unaffected by external humidity.

[0011] Marshmallow root extract stimulates the skin's natural moisturizing mechanism, reduces water evaporation, minimizes transepidermal water loss, and provides sustained hydration. Its rich polysaccharide components possess excellent antioxidant capabilities, protecting intercellular lipids in the stratum corneum from oxidation, capturing reactive oxygen species generated in lipid peroxidation chain reactions, and strengthening barrier stability. Simultaneously, the polysaccharides promote cell regeneration and repair. In this composition, Marshmallow root extract provides a favorable hydration environment for the other active ingredients, and its antioxidant effects synergistically work with the anti-photoaging effects of tetrahydromethylpyrimidine carboxylic acid.

[0012] The core innovation of this invention lies in the multi-level synergistic effect of the five active components across three efficacy dimensions. In terms of barrier repair, ceramide NP rebuilds from within the lipid layered structure, phytosterol oleate replenishes from the sterol component level, tetrahydromethylpyrimidine carboxylic acid stabilizes at the protein-lipid interface, and marshmallow root extract provides support from the hydration environment level. Together, these four components achieve comprehensive barrier repair at different levels. In terms of photoprotection, tetrahydromethylpyrimidine carboxylic acid provides DNA protection and cell membrane stability, dipotassium glycyrrhizate and phytosterol oleate inhibit photoinduced inflammatory responses through different pathways, and marshmallow root extract scavenges photogenerated ROS through antioxidant action, forming a complete photoprotection chain from DNA protection to antioxidant defense. In terms of whitening, dipotassium glycyrrhizate helps reduce melanin synthesis, tetrahydromethylpyrimidine carboxylic acid controls excessive pigmentation at its source by reducing UV-induced pigmentation, and barrier repair provides a favorable skin environment for the stable penetration and effectiveness of whitening ingredients.

[0013] Preferably, the composition comprises the following components in parts by weight: 0.5-1.5 parts of tetrahydromethylpyrimidine carboxylic acid, 0.05-0.5 parts of dipotassium glycyrrhizate, 0.1-0.5 parts of phytosterol oleate, 0.1-0.5 parts of ceramide NP, and 0.3-1.0 parts of marshmallow root extract.

[0014] More preferably, the composition comprises the following components in parts by weight: 1 part tetrahydromethylpyrimidine carboxylic acid, 0.1 part dipotassium glycyrrhizate, 0.2 parts phytosterol oleate, 0.1 part ceramide NP, and 0.5 parts marshmallow root extract.

[0015] Experimental research revealed that the dosage and ratio of the five active ingredients in this invention have a significant impact on the core efficacy of the composition in terms of barrier repair, photoprotection, and whitening. The components do not simply act additively; their synergistic effect is highly dependent on a specific ratio range. When the optimal mass ratio defined by this invention is used, each active ingredient can precisely match its action pathway, maximizing the synergistic effect between components and thus maximizing the overall skincare efficacy of the composition. If the proportions of each component deviate from the preferred range of this invention, it will directly disrupt the compatibility balance between the components, leading to a weakening or even failure of the synergistic effect. The components will not be able to complement each other, ultimately resulting in a significant decrease in the composition's barrier repair and other performance characteristics.

[0016] Secondly, the present invention provides the application of the repair composition in the preparation of cosmetics.

[0017] Preferably, the cosmetics include cosmetics with skin barrier repair function, cosmetics with photoprotection function, or cosmetics with whitening function.

[0018] Preferably, the cosmetics include, but are not limited to, lotions, creams, serums, masks, or gels.

[0019] The third invention provides a repair cosmetic, the cosmetic comprising the repair composition.

[0020] Preferably, the cosmetic further includes a cosmetic matrix, which includes at least one of a chelating agent, a moisturizer, a preservative, an emulsifier, and a solubilizer.

[0021] Preferably, the chelating agent comprises disodium EDTA; and / or, the humectant comprises butylene glycol and / or 1,2-hexanediol; and / or, the preservative comprises 1,2-hexanediol; and / or, the emulsifier comprises sodium stearoyl glutamate; and / or, the thickener comprises xanthan gum.

[0022] Preferably, the cosmetic comprises the following components in parts by weight: 0.01-3 parts tetrahydromethylpyrimidine carboxylic acid, 0.00001-2 parts dipotassium glycyrrhizate, 0.00005-3 parts phytosterol oleate, 0.0001-3 parts ceramide NP, 0.0000005-2 parts marshmallow root extract, 0.005-0.05 parts chelating agent, 1-5 parts moisturizer, 0.1-0.5 parts preservative, 0.01-0.1 parts emulsifier, and 0.01-0.1 parts thickener.

[0023] Fourthly, the present invention provides a method for preparing the aforementioned repair composition, comprising the following steps: (1) Heat water to 75-80℃, add chelating agent and humectant, and stir to dissolve; (2) Add thickener and emulsifier, and stir until swollen and evenly dispersed; (3) Cool down to below 45°C, add the repair composition and preservative, and stir evenly; (4) Adjust the pH to 5.5-6.5 and homogenize to obtain the repair cosmetic.

[0024] Compared with the prior art, the beneficial effects of the present invention are as follows: (1) The composition of this invention is made by scientifically compounding five functional active ingredients—tetrahydromethylpyrimidine carboxylic acid, dipotassium glycyrrhizate, phytosterol oleate, ceramide NP, and marshmallow root extract—within a specific ratio range. The physicochemical properties and mechanisms of action of each component are different and complementary, avoiding the shortcomings of single active ingredients, such as limited scope of action, single efficacy, and weak skin care effect. The five ingredients rely on unique targets and pathways of action to form a multi-level, full-chain synergistic effect system in three core dimensions: skin barrier repair, photodamage protection, and whitening and skin evening, which significantly improves the overall skin care efficacy of the composition.

[0025] (2) All components of this invention are safe raw materials widely used in the cosmetics field. Each component has stable chemical properties and can maintain its activity under a wide range of pH and temperature conditions, and has good compatibility. Detailed Implementation

[0026] To better illustrate the objectives, technical solutions, and advantages of this invention, the invention will be further described below with reference to specific embodiments. Those skilled in the art should understand that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

[0027] Unless otherwise specified, all raw materials used in the following examples and comparative examples are commercially available general-purpose materials.

[0028] Examples 1-6 Examples 1-6 provide a repairing serum, the formula of which is shown in Table 1 (total weight parts: 100 parts). The preparation method of the serum includes the following steps: (1) Heat purified water to 80°C, and add disodium EDTA, butanediol, and 1,2-hexanediol in sequence, stirring to dissolve; (2) Add xanthan gum and sodium stearoyl glutamate, and stir until fully swollen and evenly dispersed; (3) Cool down to below 45°C, add tetrahydromethylpyrimidine carboxylic acid and dipotassium glycyrrhizate in sequence, and stir until completely dissolved to obtain a mixture; (4) Disperse phytosterol oleate and ceramide NP in an appropriate amount of butanediol beforehand, add them to the mixture in step (3), and stir until homogeneous; (5) Add marshmallow root extract and p-hydroxyacetophenone, and stir well; (6) Adjust the pH to 5 and homogenize to obtain the essence.

[0029] Table 1. Formulation table (parts by weight) of the serums described in Examples 1-6 Comparative Examples 1-10 Comparative Examples 1-10 provide an essence, the formula of which is shown in Table 2 (total weight parts: 100 parts). The preparation method of the essence is the same as that of the examples, the only difference being the formula.

[0030] Table 2. Formulation table (parts by weight) of the serums described in Comparative Examples 1-10 Comparative Example 11 This comparative example provides an essence that differs from Example 5 only in that an equal amount of phytosterol is used to replace phytosterol oleate, while the other components and amounts remain unchanged.

[0031] Comparative Example 12 This comparative example provides an essence that differs from Example 5 only in that an equal amount of Glycyrrhiza uralensis root extract is used to replace the Althaea sylvestris root extract, while the other components and amounts remain unchanged.

[0032] Example 1 This efficacy example uses the serums described in Examples 1-6 and Comparative Examples 1-12 as test samples, and transepidermal water loss (TEWL) and stratum corneum moisture content as the main evaluation indicators to evaluate their repair effect on the skin barrier. The specific test methods are as follows: Recruit 180 participants aged 25-45 years with mild to moderate skin barrier impairment (TEWL value ≥15 g / m²). 2Female subjects (h) were randomly divided into 18 groups (Example 1-6 groups, Comparative Examples 1-12 groups), with 10 subjects in each group. Each group used the corresponding sample twice daily, morning and evening, for 28 consecutive days. The TEWL value and stratum corneum moisture content of the subjects' facial cheeks were measured before use (D0), on day 7 (D7), day 14 (D14), and day 28 (D28). TEWL was measured using a Tewameter TM300 instrument, and stratum corneum moisture content was measured using a Corneometer CM825 instrument. Before measurement, subjects sat quietly for 30 minutes in a constant temperature and humidity room at 22±2℃ and 50±5% humidity. Specific test results are shown in Tables 3-4.

[0033] Table 3. TEWL variation of different test samples (unit: g / m³) 2 h) Case Table 4. Changes in stratum corneum moisture content (unit: AU) of different test samples The results in Tables 3-4 show that the serum containing the composition prepared according to the technical solution of the present invention can effectively reduce skin barrier damage and significantly increase the moisture content of the stratum corneum, achieving excellent barrier repair effects. In particular, the serum described in Example 5 has the best barrier repair effect.

[0034] Comparative Examples 1-8, while maintaining the same total weight percentage of active ingredients as in Example 5, showed a significant decrease in barrier repair performance compared to Example 5 when any one or two of the five active ingredients—dipotassium glycyrrhizate, ceramide NP, tetrahydromethylpyrimidine carboxylic acid, phytosterol oleate, and marshmallow root extract—were removed. This indicates that the synergistic effect of the five active ingredients is crucial for ensuring the composition's efficient barrier repair; none of the components can be omitted.

[0035] When the proportions of the five active ingredients in Comparative Examples 9-10 deviate from the preferred proportions of this invention, even if the total amount of these two groups of active ingredients is higher than that in Example 5, the overall barrier repair effect of the product is still weaker than that in Example 5. This indicates that each active ingredient must be strictly matched to the preferred proportions of this invention; an imbalance in the proportions will significantly weaken the repair effect, and it is not true that the higher the amount of active ingredients added, the better the efficacy.

[0036] When comparative examples 11-12 replaced the phytosterol oleate and marshmallow root extract in this invention with raw materials of similar properties, the barrier repair efficacy of the products was reduced to varying degrees compared to Example 5. This indicates that the active components in the formulation of this invention cannot be arbitrarily replaced with conventional raw materials of the same type. Specific component combinations can form a stable synergistic effect, and replacing any specific component will destroy the synergistic system and reduce the overall skin care efficacy of the composition.

[0037] Example 2 This efficacy example uses the serums described in Examples 5 and 6, as well as Comparative Examples 1 and 3, as test samples to test their protective and repairing effects against UV-induced skin damage, thereby verifying and evaluating their photoprotective efficacy. The specific test methods are as follows: (1) In vitro cell experiments: Human immortalized keratinocytes (HaCaT cells) were used for in vitro photoprotection evaluation. The cells were divided into a blank control group, a UV model group (UVB irradiation only 30 mJ / cm²), Example 5 group, Example 6 group, Comparative Example 3 group (without tetrahydromethylpyrimidine carboxylic acid), and Comparative Example 1 group (without dipotassium glycyrrhizate). After UV irradiation, the cells were cultured for another 24 hours, and the following indicators were detected: cell viability (MTT method); thymine dimer (CPD) content (ELISA method); intracellular ROS level (DCFH-DA fluorescent probe method); secretion of inflammatory factors IL-6 and TNF-α (ELISA method). The specific test results are shown in Table 4.

[0038] (2) Human efficacy test: Forty subjects were recruited. Five 2×2cm test areas were selected on the inner forearm and applied to the areas of Example 5, Example 6, Comparative Example 3, blank matrix, and untreated control, respectively. Thirty minutes after application, UVB at 1.5 times the minimum erythema dose (MED) was irradiated using a sunlight simulator. The erythema index (Mexameter MX18) and skin damage recovery of each area were assessed 24 hours after irradiation. The specific test results are shown in Table 5.

[0039] Table 4. Results of in vitro cell experiments on different test samples Table 5. Changes in human erythema index (24 hours after irradiation) in different test samples In vitro experiments showed that Example 5 increased cell viability after UV irradiation from 52.3% to 87.5%, significantly better than Comparative Example 3 (62.8%), which lacked tetrahydromethylpyrimidine carboxylic acid. Regarding DNA protection, Example 5 reduced CPD content to 25.9% (2.2 / 8.5) in the UV model group, while Comparative Example 3 only decreased to 80.0% (6.8 / 8.5), demonstrating that tetrahydromethylpyrimidine carboxylic acid is the core active component in the formulation that exerts photoprotective effects. Furthermore, the other components in the formulation can synergistically enhance its photoprotective efficacy, further significantly improving the overall photoprotective efficacy of the formulation. In terms of ROS levels, Example 5 reduced it to near baseline levels (1.5 vs 1.0), confirming that the composition possesses excellent antioxidant protective properties and can effectively alleviate UV-induced oxidative stress damage. In human erythema experiments, Example 5 achieved an erythema reduction rate of 62.5%, significantly better than Comparative Example 3 (28.5%), further confirming the excellent application effects of the specific formulation composition in human UV protection and improving sun-damaged skin.

[0040] Example 3 This effect example uses the serums described in Examples 5 and 6, and Comparative Examples 1 and 3 as test samples to test their whitening and brightening effects. The specific test methods are as follows: (1) In vitro tyrosinase inhibition experiment: The mushroom tyrosinase inhibition experiment model was used, with L-DOPA as the substrate, and the inhibition rate of tyrosinase activity of Example 5, Comparative Example 1 (without dipotassium glycyrrhizate), Comparative Example 3 (without tetrahydromethylpyrimidine carboxylic acid) and blank control was detected. The specific test results are shown in Table 6.

[0041] (2) B16 melanoma cell experiment: Mouse B16 melanoma cells were treated with Example 5, Example 6, Comparative Example 1 and blank control for 72 hours respectively, and the melanin content and intracellular tyrosinase activity were detected. The specific test results are shown in Table 7.

[0042] (3) Human skin whitening efficacy test: Sixty female subjects with mild to moderate facial pigmentation were recruited and randomly divided into Example 5 group, Example 6 group, and Comparative Example 1 group, with 20 subjects in each group. The treatment lasted for 56 consecutive days, and the facial L* value (VISIA-CR skin analyzer) and pigmentation area (quantitatively measured using image analysis software) were measured at D0, D14, D28, and D56. Specific test results are shown in Tables 8-9.

[0043] Table 6. Results of tyrosinase inhibition experiments for different test samples. Table 7. Experimental results of B16 melanoma cells from different test samples. Table 8. Changes in L* values ​​of different test samples after human skin whitening efficacy testing. In the tyrosinase inhibition experiment, Example 5 showed an inhibition rate of 52.6%, significantly higher than Comparative Example 1 (18.2%) lacking dipotassium glycyrrhizate and Comparative Example 3 (38.5%) lacking tetrahydromethylpyrimidine carboxylic acid. Comparative Example 1 (without dipotassium glycyrrhizate) had the lowest inhibition rate, demonstrating that dipotassium glycyrrhizate is the core contributing component for whitening efficacy. While Comparative Example 3 contained dipotassium glycyrrhizate but lacked tetrahydromethylpyrimidine carboxylic acid, its inhibition rate was also lower than that of Example 5, indicating that the antioxidant and cell-protective effects of tetrahydromethylpyrimidine carboxylic acid enhance the whitening effect. In the B16 cell experiment, Example 5 reduced melanin content to 52.8% of the blank control and tyrosinase activity to 48.6%, both significantly better than Comparative Example 1, and the cell survival rate remained at 99.1%, demonstrating that the whitening effect of the composition was within a safe range.

[0044] In human skin whitening tests, Example 5 showed a 6.3-unit increase in L* value after 56 days, superior to Comparative Example 1 (+2.4); the area of ​​pigmentation decreased by 36.2%, approximately 3.4 times that of Comparative Example 1 (10.6%). These results fully demonstrate the significant advantages of Example 5 as the optimal formulation in terms of whitening efficacy. This advantage stems from the synergistic effect of dipotassium glycyrrhizate's tyrosinase inhibition, the control of photodamage at the source by tetrahydromethylpyrimidine carboxylic acid, and the creation of a favorable skin environment for the penetration of whitening ingredients through intact barrier repair.

[0045] Finally, it should be noted that the above embodiments are used to illustrate the technical solutions of the present invention and not to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. A repair composition, characterized in that, The composition comprises the following components in parts by weight: 0.01-3 parts tetrahydromethylpyrimidine carboxylic acid, 0.00001-2 parts dipotassium glycyrrhizate, 0.00005-3 parts phytosterol oleate, 0.0001-3 parts ceramide NP, and 0.0000005-2 parts marshmallow root extract.

2. The repair composition as claimed in claim 1, characterized in that, The composition comprises the following components in parts by weight: 0.5-1.5 parts of tetrahydromethylpyrimidine carboxylic acid, 0.05-0.5 parts of dipotassium glycyrrhizate, 0.1-0.5 parts of phytosterol oleate, 0.1-0.5 parts of ceramide NP, and 0.3-1 parts of marshmallow root extract.

3. The repair composition as described in claim 2, characterized in that, The composition comprises the following components in parts by weight: 1 part tetrahydromethylpyrimidine carboxylic acid, 0.1 part dipotassium glycyrrhizate, 0.2 parts phytosterol oleate, 0.1 part ceramide NP, and 0.5 parts marshmallow root extract.

4. The use of the repair composition according to any one of claims 1-3 in the preparation of cosmetics.

5. The application as described in claim 4, characterized in that, The cosmetics mentioned include cosmetics with skin barrier repair function, cosmetics with photoprotection function, or cosmetics with whitening function.

6. A repair cosmetic product, characterized in that, The cosmetic product includes the repair composition according to any one of claims 1-3.

7. The repair cosmetic as described in claim 6, characterized in that, The cosmetic also includes a cosmetic matrix, which includes at least one of a chelating agent, a moisturizer, a preservative, an emulsifier, and a solubilizer.

8. The repair cosmetic as described in claim 7, characterized in that, The chelating agent includes disodium EDTA; and / or the humectant includes butylene glycol and / or 1,2-hexanediol; and / or the preservative includes 1,2-hexanediol; and / or the emulsifier includes sodium stearoyl glutamate; and / or the thickener includes xanthan gum.

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