A pathological department whole organ large tissue section sampling device

CN122591329APending Publication Date: 2026-08-18THE THIRD MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL
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Patent Information

Application Number
CN202610618494.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-07
Publication Date
2026-08-18

AI Technical Summary

Technical Problem

[0005]本发明提供一种病理科用全器官大组织切片取材装置,以解决现有取材设备中的通过螺栓连接结构或卡扣连接机构使刀片与刀柄连接,刀片的装卸方式较为原始和繁琐,不能实现快速、安全地更换刀片,导致整体取材效率偏低的技术问题

Benefits of technology

[0019]In the above solution, clamps are installed on both sides of the fixed-spacing tooth holder, and multiple sets of clamping plates are integrated into the housing of the clamps. A control component is used to achieve synchronous opening or closing of all clamping plates. Operators can easily clamp or release multiple blades inserted into all gaps simultaneously without needing to individually bolt or snap-fit ​​each blade. This changes the current situation where blade loading and unloading is cumbersome and time-consuming, significantly improving the efficiency of whole-organ large tissue sectioning.

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Abstract

This invention provides a whole-organ large tissue sectioning device for pathology, belonging to the field of medical device technology. It includes a support base, two sets of sizing teeth on both sides of the support base, and two sets of positioning components on the other two sides of the support base. The surface of the raised portion of the support base and the surface of the sizing teeth are provided with multiple sets of spaced gaps for inserting the blades. The bottom sides of the raised portion of the support base extend outwards and are fixedly connected to the two sets of sizing teeth. Clamps are connected to both sides of the sizing teeth via slide rail components. In this design, by setting clamps on both sides of the sizing teeth and integrating multiple sets of clamping plates within the clamp housing, and cooperating with a control component, all clamping plates can be opened or closed synchronously. Operators only need simple operation to simultaneously clamp or release multiple blades inserted into all gaps, changing the cumbersome and time-consuming blade loading and unloading situation of existing devices, and significantly improving the efficiency of whole-organ large tissue sectioning.
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Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a whole-organ large tissue section sampling device for pathology. Background Technology

[0002] Prostate cancer is one of the most common malignant tumors of the urinary system in men, and radical prostatectomy is currently the most effective treatment for localized prostate cancer. Postoperative pathological evaluation of the resected prostate specimen is of great clinical significance for determining the surgical margins, assessing tumor stage, guiding subsequent treatment, and predicting prognosis.

[0003] Compared to other routine postoperative tissue sections, large-scale prostate tissue sections are not only larger in volume but also require a higher level of technical skill. Currently, the sampling process for large-scale prostate tissue sections primarily relies on manually dividing the prostate specimen into several equal parts using a biopsy knife. However, because prostate cancer mostly occurs in elderly men, and most elderly men have prostate enlargement or other related issues to varying degrees, the prostates of different patients exhibit complex anatomical shapes and sizes, which further complicates the manual sampling process. Even experienced pathologists find it difficult to ensure the relative consistency of thickness across different sections, and the uniformity and regularity of different sections are hard to guarantee.

[0004] Although some auxiliary sampling devices for large-scale prostate tissue sectioning exist in existing technologies, such as those using a thick plate composed of parallel vertical plates to fix the prostate specimen and then cutting along the gaps between the plates to achieve relatively uniform segmentation, these devices still present significant operational inconveniences. Operators need to insert the blade sequentially into the gaps between adjacent vertical plates for multiple cuts, and connect it to the blade handle via bolts or snap-fit ​​mechanisms. The blade loading and unloading method is relatively primitive and cumbersome, preventing quick and safe blade replacement and resulting in low overall sampling efficiency. Therefore, a large-scale prostate tissue sectioning device for pathology departments is proposed. Summary of the Invention

[0005] This invention provides a whole organ large tissue sectioning device for pathology departments, which solves the technical problem that existing sampling equipment uses bolted or snap-fit ​​connections to connect the blade to the handle, resulting in a primitive and cumbersome blade loading and unloading method that cannot achieve quick and safe blade replacement, leading to low overall sampling efficiency.

[0006] To solve the above-mentioned technical problems, the present invention provides the following technical solution:

[0007] A whole-organ large tissue sectioning device for pathology includes a support base, two sets of sizing teeth symmetrically arranged on both sides of the support base, and two sets of positioning components arranged on the other two sides of the support base. The support base includes a protrusion, and the surface of the protrusion and the surface of the sizing teeth are provided with multiple sets of spaced gaps for cutting. The bottom sides of the protrusion of the support base extend outward and are fixedly connected to the two sets of sizing teeth respectively. Both sides of the sizing teeth are connected to clamps through slide rail assemblies, and the clamps are supported to move up and down through the slide rail assemblies.

[0008] Each clamp includes a housing, the upper side of which and the side near the fixed tooth seat are open. Multiple sets of clamping plates are provided inside the housing, corresponding to the number and position of the gaps. Each set of clamping plates has two plates located on both sides of the corresponding gap. Each clamp is provided with a control component, which is used to operate each set of clamping plates to open or close synchronously.

[0009] Optionally, the control component includes an elastic support and a pressing component. The elastic support includes multiple sets of grooves formed inside the housing, the number and position of which correspond to each set of clamping plates. The lower part of the clamping plate is slidably installed inside the corresponding groove, and a horizontal insert rod is fixedly connected inside each groove. The insert rod slides through the two clamping plates inside the groove. A first spring is fixedly connected between the clamping plate and the inner wall of the groove. The first spring is sleeved on the outer surface of the insert rod, and the first spring causes the two clamping plates to be located on both sides within the corresponding gap.

[0010] Optionally, the pressing component of the control assembly includes a control frame. The bottom wall of the housing has a cavity, and the sliding grooves are all connected to the cavity. The control frame is a rectangular frame structure. The two vertical parts of the control frame slide through the housing. The upper horizontal part of the control frame is located in the cavity of the housing, and the lower horizontal part of the control frame is located below the housing. The lower parts of the clamping plates extend into the cavity and are fixedly connected to wedge plates. The upper horizontal part of the control frame is fixedly connected to multiple sets of frame plates. The number and position of the frame plates correspond to the multiple sets of clamping plates. Each set of clamping plates has a corresponding frame plate below it. The bottom of the wedge plate passes through and is located in the corresponding frame plate.

[0011] Optionally, the inclined sides of the two wedge plates in each group are arranged facing away from each other, and the lateral width of the wedge plates gradually decreases from top to bottom, and the lateral width of the inner side of the frame plate is less than the sum of the lateral widths of the two clamping plates.

[0012] Optionally, magnetic blocks are fixedly connected to the side of the clamping plate opposite to the slide groove, and the corresponding two magnetic blocks attract each other.

[0013] Optionally, it also includes a limiting component disposed on the top of the housing. The limiting component includes a baffle, and connecting blocks are fixedly connected to both sides of the lower surface of the baffle. The connecting blocks are located on the side close to the fixed tooth seat. Grooves adapted to the connecting blocks are opened on both sides of the upper surface of the housing. The connecting blocks are inserted into the grooves and support movement along the grooves, so that the baffle moves closer to or away from the fixed tooth seat.

[0014] Optionally, a horizontal guide rod is fixedly connected inside each of the grooves. The guide rod slides through the connecting block. A second spring is fixedly connected between the connecting block and the inner wall of the groove. The second spring is sleeved on the outer surface of the guide rod. A movable seat is fixedly connected to the outer surface of the housing. A vertical connecting rod is slidably installed inside the movable seat. The lower end of the connecting rod extends through to the outside of the movable seat and is connected to the control frame. A connecting rope is fixedly connected to the bottom of the connecting block. Guide grooves are opened on the bottom of the outer wall of the groove near the fixed tooth seat and on the bottom of the side wall of the movable seat near the fixed tooth seat. The connecting rope extends through the guide groove to the inside of the movable seat and is fixedly connected to the upper end of the connecting rod.

[0015] Optionally, when the second spring is not subjected to external force, the baffle is located on the side of the upper surface of the housing away from the fixed tooth seat, the upper surface of the housing remains open, and the connecting rope is taut.

[0016] Optionally, the slide rail assembly includes a slide fixedly installed on the side wall of the fixed tooth seat. A vertical rod is fixedly connected inside the slide. A vertical groove is opened in the side wall of the slide. A connecting plate is slidably installed inside the vertical groove. One end of the connecting plate is fixedly connected to the movable seat. The other end of the connecting plate slides through the vertical rod. A third spring is sleeved on the outer surface of the vertical rod. The third spring is used to support the connecting plate.

[0017] Optionally, the positioning component includes a positioning seat located on the side adjacent to the fixed sparse tooth seat. The positioning seat has a rectangular groove, and a first push rod is fixedly connected to the bottom surface of the rectangular groove. A horizontal positioning frame is fixedly connected to the telescopic end of the first push rod. A movable sparse tooth seat is provided between each fixed sparse tooth seat and the protrusion of the support base. The surface of the movable sparse tooth seat has multiple parallel gaps distributed at intervals. The gaps on the movable sparse tooth seat are matched in number, position, and size with the gaps on the fixed sparse tooth seat and the gaps on the protrusion of the support base. The bottom surfaces of the gaps on the support base, the gaps on the fixed sparse tooth seat, and the gaps on the movable sparse tooth seat are located on the same horizontal line. The bottom of both the positioning seat and the movable sparse tooth seat are connected to the outer wall of the protrusion of the support base by a second push rod. The bottom surface of the movable sparse tooth seat is slidably connected to the top surface of the support base.

[0018] The beneficial effects of the above-mentioned technical solution of the present invention are as follows:

[0019] In the above solution, clamps are installed on both sides of the fixed-spacing tooth holder, and multiple sets of clamping plates are integrated into the housing of the clamps. A control component is used to achieve synchronous opening or closing of all clamping plates. Operators can easily clamp or release multiple blades inserted into all gaps simultaneously without needing to individually bolt or snap-fit ​​each blade. This changes the current situation where blade loading and unloading is cumbersome and time-consuming, significantly improving the efficiency of whole-organ large tissue sectioning. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0021] Figure 2 This is a schematic diagram of the structure when the blade of the present invention is installed;

[0022] Figure 3 This is a cross-sectional view of the housing of the present invention;

[0023] Figure 4 For the present invention Figure 3 Enlarged view of point A in the middle;

[0024] Figure 5 This is a schematic diagram of the structure of the clamping plate of the present invention when it clamps the blade;

[0025] Figure 6 This is a partial structural diagram of the shell of the present invention when the upper surface is open;

[0026] Figure 7 This is a partial structural diagram of the present invention when the baffle is placed on the upper surface of the housing;

[0027] Figure 8 This is a schematic diagram of the structure of the limiting component of the present invention;

[0028] Figure 9 For the present invention Figure 7 Enlarged view of point B in the middle.

[0029] [Figure Labels]

[0030] 1. Support base; 2. Fixed toothed seat;

[0031] 3. Positioning assembly; 31. Positioning seat; 32. First push rod; 33. Positioning frame; 34. Moving tooth seat; 35. Second push rod;

[0032] 4. Fixture; 41. Housing; 42. Clamping plate;

[0033] 5. Control components; 51. Slide groove; 52. Insert rod; 53. First spring; 54. Magnetic block; 55. Control frame; 56. Frame plate; 57. Wedge plate;

[0034] 6. Limiting component; 61. Baffle; 62. Groove; 63. Second spring; 64. Movable seat; 65. Connecting rod; 66. Connecting rope; 67. Connecting block; 68. Guide rod; 69. Guide groove;

[0035] 7. Slide rail assembly; 71. Slide block; 72. Vertical rod; 73. Third spring; 74. Vertical groove; 75. Connecting plate. Detailed Implementation

[0036] To make the technical problems, technical solutions and advantages of the present invention clearer, a detailed description will be given below in conjunction with the accompanying drawings and specific embodiments.

[0037] like Figures 1 to 9 As shown, an embodiment of the present invention provides a whole-organ large tissue section sampling device for pathology, including a support base 1, two sets of sizing teeth 2 disposed on both sides of the support base 1, and two sets of positioning components 3 disposed on the other two sides of the support base 1. Both the support base 1 and the sizing teeth 2 have multiple spaced gaps for incision. The number, position, and size of the gaps on the protruding surface of the support base 1 and the gaps on the surface of the sizing teeth 2 are matched. The bottom sides of the protruding part of the support base 1 extend outwards and are fixedly connected to the two sets of sizing teeth 2 respectively. Clamps 4 are connected to both sides of the sizing teeth 2 via slide rail assemblies 7, and the clamps 4 can move up and down via the slide rail assemblies 7.

[0038] Each clamp 4 includes a housing 41. The upper side of the housing 41 and the side near the fixed tooth seat 2 are open. Multiple sets of clamping plates 42 are provided inside the housing 41, corresponding to the number and position of the gaps. Each set of clamping plates 42 has two plates located on both sides of the corresponding gap. Each clamp 4 is provided with a control component 5, which is used to operate each set of clamping plates 42 to open or close synchronously.

[0039] In this embodiment, the support base 1 serves as the base of the entire device, placed on the operating table to stably support all other components. Two sets of sizing teeth 2 are arranged opposite each other on both sides of the support base 1, such as the left and right sides or the front and back sides. Each sizing tooth 2 and the support base 1 have multiple spaced parallel gaps machined on their surfaces. These gaps guide the direction of the blade's downward cut, ensuring that the blade can vertically cut into the tissue specimen along a predetermined trajectory during cutting. Two sets of positioning components 3 are provided on the other opposite sides of the support base 1, i.e., the other sides without sizing teeth 2. The positioning components 3 are used to hold the prostate tissue specimen to be cut horizontally, preventing lateral displacement of the specimen during cutting and ensuring the stability of the cut and the uniformity of the slice thickness. Clamps 4 are connected to both sides of the sizing teeth 2 via slide rail assemblies 7. The slide rail assemblies 7 allow the clamps 4 to move vertically up and down while maintaining the relative positional accuracy between the clamps 4 and the sizing teeth 2, preventing the clamps 4 from tilting during movement.

[0040] When the operator prepares to cut, the entire prostate tissue specimen is first placed between the support base 1 and the positioning tooth seat 2, and fixed by the positioning component 3. Then, multiple blades are inserted sequentially into the corresponding gaps between the positioning tooth seat 2 and the support base 1. After insertion, the blades extend naturally into the housing 41 of the clamps 4 on both sides and fall into the gaps between the clamping plates 42. At this time, the control component 5 is operated to drive all the clamping plates 42 to close synchronously towards the center. The two clamping plates 42 in each group move relative to each other, clamping the ends of the blades from both sides, thus firmly fixing the blades between the clamps 4 and the positioning tooth seat 2. Because all the clamping plates 42 move synchronously, multiple blades can be clamped at the same time without the need for individual bolts or clips to fix each blade, greatly improving the efficiency of blade loading and unloading. After clamping is completed, the operator presses down on the clamps 4, and the clamps 4 move downward along the slide rail assembly 7. Since the blades are fixed by the clamping plate 42 and their blade bodies are located in the gap between the fixed tooth seat 2 and the support base 1, the downward movement of the clamp 4 will cause all the blades to simultaneously cut the tissue specimen vertically downwards. After cutting, the control component 5 is released, and the clamping plate 42 automatically opens under the action of elastic elements such as the first spring 53, allowing all the blades to be easily removed. This structure realizes rapid clamping and overall cutting of the blades, solving the problems of cumbersome blade loading and unloading and low cutting efficiency in the prior art.

[0041] Furthermore, the gap between the support base 1 and the sizing tooth base 2, i.e., the center-to-center distance between two adjacent gaps, determines the thickness of the tissue section obtained in each cut. This gap can be selected or adjusted according to actual clinical needs. In the standard procedure for large tissue sections of the entire prostate organ, the routine section thickness is 3mm to 5mm.

[0042] like Figures 3 to 4 As shown, the control component 5 includes an elastic support and a pressing component. The elastic support includes multiple slots 51 opened in the housing 41 corresponding to the number of positions of each set of clamping plates 42. The lower part of the clamping plate 42 is slidably installed in the corresponding slot 51, and a rod 52 is fixedly connected inside each slot 51. The rod 52 slides through the two clamping plates 42 in the slot 51. A first spring 53 is fixedly connected between the two clamping plates 42 and the two inner walls of the slot 51, respectively. The first spring 53 is sleeved on the outer surface of the rod 52, and the first spring 53 makes the two clamping plates 42 located on both sides of the corresponding gap.

[0043] In this embodiment, the width of the groove 51 is slightly greater than the sum of the thicknesses of the two clamping plates 42. The length direction of the groove 51 and the axial direction of the insertion rod 52 are consistent with the moving direction of the clamping plate 42. The groove 51 provides a precise guide track for the horizontal sliding of the clamping plate 42. By setting the insertion rod 52, the sliding trajectory of the clamping plate 42 is further constrained, so that the two clamping plates 42 always move along the same straight line. When the first spring 53 is not subjected to other external forces, it is in a naturally extended state. Its elastic force ensures that the two clamping plates 42 are located on both sides of the corresponding gap, that is, in an open state, so that the blade tip can be inserted between the two clamping plates 42 without obstruction.

[0044] like Figure 3 and Figure 5 As shown, the pressing component of the control assembly 5 includes a control frame 55. The bottom wall of the housing 41 has a cavity, and the sliding grooves 51 are all connected to the cavity. The control frame 55 is a rectangular frame structure. The vertical parts on both sides of the control frame 55 slide through the housing 41. The upper horizontal part of the control frame 55 is located in the cavity of the housing 41, and the lower horizontal part of the control frame 55 is located below the housing 41. The lower parts of the clamping plates 42 all extend into the cavity and are fixedly connected to wedge plates 57. The upper horizontal part of the control frame 55 is fixedly connected to multiple frame plates 56 corresponding to the number and position of each set of clamping plates 42. The bottom of the wedge plates 57 is located in and passes through the corresponding frame plates 56. The inclined sides of the two corresponding wedge plates 57 in a set of clamping plates 42 are arranged facing away from each other, and the lateral width of the wedge plates 57 gradually decreases from top to bottom, forming a trapezoidal or triangular cross-section that is wider at the top and narrower at the bottom. This shape causes the side of the wedge plate 57 to form an inclined guide surface. The inner lateral width of the frame plate 56 is less than the sum of the lateral widths of the two clamping plates 42. Since the inner width of the frame plate 56 is less than this sum, when the frame plate 56 moves upward, its inner edge will inevitably come into contact with the inclined surface of the wedge plate 57 and be squeezed.

[0045] In the initial state, the control frame 55 and the frame plate 56 are both at their lowest positions. At this time, the upper inner edge of the frame plate 56 is in contact with or has a small gap with the lower edge of the wedge plate 57's inclined surface. When the operator pushes the lower horizontal part of the control frame 55 upwards, the entire control frame 55 moves upwards, causing all the frame plates 56 to move upwards synchronously, and the frame plates 56 slide relative to the wedge plate 57. During the upward movement of the frame plate 56, its inner edge presses against the inclined surface of the wedge plate 57. Since the wedge plate 57 is fixedly connected to the clamping plate 42, and the clamping plate 42 can only slide horizontally within the slide groove 51, the upward pressing action of the frame plate 56 forces the wedge plate 57 to move horizontally, thereby causing the two clamping plates 42 to close relative to each other, clamping the blade. When the operator releases the control frame 55, under the elastic force of the first spring 53, the clamping plate 42 moves the wedge plate 57 outwards, and simultaneously the inclined surface of the wedge plate 57 presses down on the frame plate 56, causing the control frame 55 to automatically return to its downward reset position. By setting up a pressing component, the single vertical upward movement is converted into a horizontal synchronous closing movement of multiple sets of clamping plates 42. The operation is simple and labor-saving, and the clamping action of all clamping plates 42 is completely synchronized, ensuring that multiple blades are clamped evenly at the same time.

[0046] like Figure 4 As shown, magnetic blocks 54 are fixedly connected to the side of the clamping plate 42 opposite to the slide groove 51, and the corresponding two sets of magnetic blocks 54 attract each other.

[0047] When the first spring 53 experiences elastic fatigue or breaks due to long-term use, and its ability to push the clamping plate 42 to open decreases, the mutual attraction of the magnetic blocks 54 remains unaffected and can still provide a stable driving force, so that the clamping plate 42 remains open even when not under the action of the control component 5, so that the blade can be inserted between the corresponding two clamping plates 42.

[0048] like Figures 6 to 9 As shown, in order to limit and protect the upper part of the blade during the cutting process, a limiting component 6 is provided on the top of the housing 41. The limiting component 6 includes a baffle 61, and connecting blocks 67 are fixedly connected to both sides of the lower surface of the baffle 61. The connecting blocks 67 are located on the side close to the fixed tooth seat 2. Grooves 62 adapted to the connecting blocks 67 are opened on both sides of the upper surface of the housing 41. The connecting blocks 67 are inserted into the grooves 62 and can move along the grooves 62, so that the baffle 61 is close to or away from the fixed tooth seat 2.

[0049] During rapid downward cutting, the blade may slightly bend or vibrate due to force. If the operator accidentally touches the upper part of the blade, there is a risk of cuts. By moving the baffle 61 to cover the housing 41, the upper part of the blade can be shielded, providing safety protection. At the same time, the baffle 61 also limits excessive vertical displacement of the blade, preventing it from coming out of the clamping plate 42 during cutting.

[0050] Specifically, guide rods 68 are fixedly connected inside the groove 62. The guide rods 68 slide through the connecting block 67. A second spring 63 is fixedly connected between the connecting block 67 and the inner wall of the groove 62. The second spring 63 is sleeved on the outer surface of the guide rod 68. A movable seat 64 is fixedly connected to the outer surface of the housing 41. A connecting rod 65 is vertically slidably installed inside the movable seat 64. The lower end of the connecting rod 65 passes through to the outside of the movable seat 64 and is connected to the control frame 55. A connecting rope 66 is fixedly connected to the bottom of the connecting block 67. Guide grooves 69 are opened on the bottom of the outer wall of the groove 62 near the fixed tooth seat 2 and on the bottom of the side wall of the movable seat 64 near the fixed tooth seat 2. The connecting rope 66 extends through the guide groove 69 into the interior of the movable seat 64 and is fixedly connected to the upper end of the connecting rod 65. When the second spring 63 is not subjected to external force, the baffle 61 is located on the upper surface of the housing 41 away from the fixed tooth seat 2. The upper surface of the housing 41 remains open, and the connecting rope 66 is taut.

[0051] When the operator pushes the control frame 55 upward, the control frame 55 moves the connecting rod 65 upward. The upward movement of the connecting rod 65 pulls the connecting rope 66. After the connecting rope 66 turns through the guide groove 69, it pulls the connecting block 67 to overcome the elastic force of the second spring 63, causing the connecting block 67 to move closer to the fixed tooth seat 2. The connecting block 67 moves the baffle 61 synchronously, so the baffle 61 automatically slides from the open position to the covered position, covering the top of the housing 41. That is to say, when the operator clamps the blade, the baffle 61 will automatically close, providing a safety protection function, without the need for manual operation of the baffle 61. Conversely, when the cutting is completed and the operator releases the control frame 55, the control frame 55 returns to its original position under its own weight or the action of the first spring 53, the connecting rod 65 moves downward, and the connecting rope 66 loosens. At this time, the elastic force of the second spring 63 pushes the connecting block 67 to move away from the fixed tooth seat 2, and the baffle 61 automatically opens, exposing the upper surface of the housing 41, making it easy to remove the blade.

[0052] like Figures 6 to 7 As shown, the slide rail assembly 7 includes a slide seat 71 fixedly installed on the side wall of the fixed tooth seat 2. A vertical rod 72 is fixedly connected inside the slide seat 71. A vertical groove 74 is opened on the side wall of the slide seat 71. A connecting plate 75 is slidably installed inside the vertical groove 74. One end of the connecting plate 75 is fixedly connected to the movable seat 64. The other end of the connecting plate 75 slides through the vertical rod 72. A third spring 73 is sleeved on the outer surface of the vertical rod 72. The top end of the third spring 73 abuts against the bottom surface of the connecting plate 75. The third spring 73 is used to support the connecting plate 75.

[0053] When not cutting, the elastic force of the third spring 73 supports the connecting plate 75, thereby keeping the entire clamp 4 in a high position for easy placement of the specimen and installation of the blade. When the operator presses down on the clamp 4 to cut, the elastic force of the third spring 73 must be overcome. The third spring 73 is compressed, the clamp 4 moves smoothly downward, and the blade cuts downward. After cutting, the clamp 4 is released, and the elastic force of the third spring 73 automatically pushes the clamp 4 back to the high position, allowing the blade to leave the cut tissue for easy removal of the slide or for the next cut.

[0054] like Figures 1 to 2 As shown, each positioning component 3 includes a positioning seat 31, which is located on the side adjacent to the positioning tooth seat 2. A rectangular groove is opened in the positioning seat 31, and a first push rod 32 is fixedly connected to the inner bottom surface of the rectangular groove in the positioning seat 31. The telescopic end of the first push rod 32 is fixedly connected to a positioning frame 33, and the axis of the positioning frame 33 is perpendicular to the axis of the positioning seat 31.

[0055] The support base 1 has a protrusion at its center, and parallel gaps on the surface of the support base 1 are provided at the protrusion. Two movable toothed seats 34 are slidably disposed between each fixed toothed seat 2 and the protrusion. The surface of the movable toothed seat 34 has gaps that match the number and position of the gaps on the surfaces of the fixed toothed seats 2 and the support base 1. In this design, the gaps have a certain depth, and the depths of the gaps on the surfaces of the fixed toothed seats 2 and the movable toothed seats 34 are equal. The bottom surfaces of the gaps on the support base 1, the fixed toothed seats 2, and the movable toothed seats 34 are located on the same horizontal line. One side of the positioning seat 31 and the bottom of the movable toothed seat 34 are connected to the protrusion of the support base 1 via a second push rod 35. The first push rod 32 is perpendicular to the protrusion, and the extension direction of the second push rod 35 is perpendicular to the side wall of the corresponding protrusion of the support base 1. A corresponding slider rail can be provided at the sliding connection between the bottom of the movable toothed seat 34 and the support base 1 to make the movement of the movable toothed seat 34 more stable. Both movable toothed seats 34 have an arc-shaped structure on opposite sides. The two positioning seats 31 and the two movable toothed seats 34 are located on the four sides of the support base 1, and are connected to the side wall of the support base 1 through the second push rod 35.

[0056] When it is necessary to fix a whole prostate organ tissue specimen, the operator places the specimen on the support base 1. Then, the first push rod 32 is activated to move it, adjusting the height of the positioning frame 33 so that the clamping point of the positioning frame 33 is located at the center of the side of the specimen. Then, the second push rod 35 corresponding to the positioning seat 31 is activated to move the positioning frame 33 until the positioning frame 33 abuts against the side of the specimen, thus positioning the specimen. In addition, depending on the size of the specimen, the second push rod 35 can be used to move the movable toothed seat 34, so that the movable toothed seat 34 can also play a role in fixing the organ tissue specimen and prevent the specimen from being deformed laterally due to pressure during cutting. The first push rod 32 and the second push rod 35 can both be existing mature electric push rod products, such as miniature linear electric push rods. Their operation and control are existing conventional technologies and will not be described in detail here.

[0057] The above description represents the preferred embodiments of the present invention. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A whole-organ large tissue section sampling device for pathology, comprising a support base, two sets of positioning teeth symmetrically arranged on both sides of the support base, and two sets of positioning components arranged on the other two sides of the support base, characterized in that... The support base includes a protrusion. The surface of the protrusion of the support base and the surface of the fixed tooth seat are provided with multiple sets of spaced gaps for cutting. The bottom sides of the protrusion of the support base extend outward and are fixedly connected to two sets of fixed tooth seats respectively. Both sides of the fixed tooth seat are connected to clamps by slide rail assemblies. The clamps are supported to move up and down by slide rail assemblies. Each clamp includes a housing, the upper side of which and the side near the fixed tooth seat are open. Multiple sets of clamping plates are provided inside the housing, corresponding to the number and position of the gaps. Each set of clamping plates has two plates located on both sides of the corresponding gap. Each clamp is provided with a control component, which is used to operate each set of clamping plates to open or close synchronously.

2. The whole-organ large tissue section sampling device for pathology department according to claim 1, characterized in that, The control component includes an elastic support and a pressing component. The elastic support includes multiple sets of sliding grooves opened inside the housing, the number and position of which correspond to each set of clamping plates. The lower part of the clamping plate is slidably installed inside the corresponding sliding groove, and a horizontal insert rod is fixedly connected inside each sliding groove. The insert rod slides through the two clamping plates inside the sliding groove. A first spring is fixedly connected between the clamping plate and the inner wall of the sliding groove. The first spring is sleeved on the outer surface of the insert rod, and the first spring causes the two clamping plates to be located on both sides within the corresponding gap.

3. The whole-organ large tissue section sampling device for pathology department according to claim 2, characterized in that, The pressing component of the control assembly includes a control frame. The bottom wall of the housing has a cavity, and the sliding grooves are all connected to the cavity. The control frame is a rectangular frame structure. The two vertical parts of the control frame slide through the housing. The upper horizontal part of the control frame is located in the cavity of the housing, and the lower horizontal part of the control frame is located below the housing. The lower parts of the clamping plates all extend into the cavity and are fixedly connected to wedge plates. The upper horizontal part of the control frame is fixedly connected to multiple sets of frame plates. The number and position of the frame plates correspond to the multiple sets of clamping plates. Each set of clamping plates has a corresponding frame plate below it. The bottom of the wedge plate passes through and is located in the corresponding frame plate.

4. The whole-organ large tissue section sampling device for pathology department according to claim 3, characterized in that, The inclined sides of the two wedge plates in each group are arranged facing away from each other, and the lateral width of the wedge plates gradually decreases from top to bottom. The lateral width of the inner side of the frame plate is less than the sum of the lateral widths of the two clamping plates.

5. The whole-organ large tissue section sampling device for pathology department according to claim 4, characterized in that, Each of the clamping plates and the side opposite to the slide groove is fixedly connected with a magnetic block, and the two corresponding magnetic blocks attract each other.

6. The whole-organ large tissue section sampling device for pathology department according to claim 2, characterized in that, It also includes a limiting component set on the top of the housing. The limiting component includes a baffle. Connecting blocks are fixedly connected to both sides of the lower surface of the baffle. The connecting blocks are located on the side close to the fixed tooth seat. Grooves adapted to the connecting blocks are opened on both sides of the upper surface of the housing. The connecting blocks are inserted into the grooves and support movement along the grooves, so that the baffle moves closer to or away from the fixed tooth seat.

7. The whole-organ large tissue section sampling device for pathology department according to claim 6, characterized in that, A horizontal guide rod is fixedly connected inside each of the grooves. The guide rod slides through the connecting block. A second spring is fixedly connected between the connecting block and the inner wall of the groove. The second spring is sleeved on the outer surface of the guide rod. A movable seat is fixedly connected to the outer surface of the housing. A vertical connecting rod is slidably installed inside the movable seat. The lower end of the connecting rod passes through to the outside of the movable seat and is connected to the control frame. A connecting rope is fixedly connected to the bottom of the connecting block. Guide grooves are opened on the bottom of the outer wall of the groove near the fixed tooth seat and on the bottom of the side wall of the movable seat near the fixed tooth seat. The connecting rope extends through the guide groove to the inside of the movable seat and is fixedly connected to the upper end of the connecting rod.

8. The whole-organ large tissue section sampling device for pathology department according to claim 7, characterized in that, When the second spring is not subjected to external force, the baffle is located on the side of the upper surface of the housing away from the fixed tooth seat, the upper surface of the housing remains open, and the connecting rope is taut.

9. The whole-organ large tissue section sampling device for pathology department according to claim 7, characterized in that, The slide rail assembly includes a slide block fixedly installed on the side wall of the fixed tooth seat. A vertical rod is fixedly connected inside the slide block. A vertical groove is opened in the side wall of the slide block. A connecting plate is slidably installed inside the vertical groove. One end of the connecting plate is fixedly connected to the movable seat. The other end of the connecting plate slides through the vertical rod. A third spring is sleeved on the outer surface of the vertical rod. The third spring is used to support the connecting plate.

10. The whole-organ large tissue section sampling device for pathology department according to claim 1, characterized in that, The positioning component includes a positioning seat located on the side adjacent to the fixed sparse tooth seat. The positioning seat has a rectangular groove, and a first push rod is fixedly connected to the bottom surface of the rectangular groove. A horizontal positioning frame is fixedly connected to the telescopic end of the first push rod. A movable sparse tooth seat is provided between each fixed sparse tooth seat and the protrusion of the support base. The surface of the movable sparse tooth seat has multiple parallel gaps distributed at intervals. The gaps on the movable sparse tooth seat are matched in number, position, and size with the gaps on the fixed sparse tooth seat and the gaps on the protrusion of the support base. The bottom surfaces of the gaps on the support base, the gaps on the fixed sparse tooth seat, and the gaps on the movable sparse tooth seat are located on the same horizontal line. The bottom of both the positioning seat and the movable sparse tooth seat are connected to the outer wall of the protrusion of the support base by a second push rod. The bottom surface of the movable sparse tooth seat is slidably connected to the top surface of the support base.