Health-care sand containing zinc cysteine and its preparation method and application

Abstract

The application discloses a health-care sand containing zinc cysteamine and a preparation method and application thereof. The health-care sand comprises the following components in parts by weight: 64 parts of river sand, 32 parts of shell powder, 2 parts of a mixture of zinc cysteamine and zeolite powder and 2 parts of premix. The premix provides, per kilogram of the health-care sand: 80000 IU of vitamin A, 34500 IU of vitamin D3, 480 mg of vitamin E, 480 mg of vitamin K3, 60 mg of vitamin B1, 217 mg of vitamin B2, 40 mg of vitamin B6, 500 µg of vitamin B12, 300 mg of nicotinamide, 11 mg of folic acid, 150 mg of pantothenic acid, 2.4 mg of biotin, 5600 mg of choline chloride, 200 mg of copper, 1062 mg of iron, 1100 mg of manganese, 0.1 mg of iodine and 0.2 mg of selenium. The application applies the zinc cysteamine to the health-care sand, can effectively improve the average daily weight gain of meat pigeons, shorten the time of taking out of the market, reduce the production cost, improve the pigeon meat production efficiency, and effectively improve the muscle nutritional value and sensory quality of the meat pigeons.

Description

Technical Field

[0001] This invention relates to the field of feed additive technology, specifically to a health-care grit containing zinc cysteamine, its preparation method, and its application. Background Technology

[0002] Currently, domestic pigeon farming mainly adopts a feeding model of "raw grain + grit" or "raw grain + pelleted feed + grit," with grit playing a particularly prominent role. Grit is a unique mineral feed for pigeons, providing them with essential trace elements for their life activities. Grit can balance feed nutrients, stimulate and enhance gizzard contraction, improve gastrointestinal digestibility, increase fertilization and hatching rates, promote squab growth and development, and improve egg production performance and egg quality. Its value for the high-quality development of the pigeon industry is self-evident. Pigeon farming is a precision farming industry; to improve efficiency, breeding techniques are crucial. Improving and innovating the use of grit for pigeons is an important method to maintain low-cost, high-efficiency pigeon farming.

[0003] Zinc plays a wide range of roles in the life processes of organisms and is a crucial mineral in the supplementation of grit for pigeons. More than 300 zinc-containing enzymes have been identified from various organisms. Zinc regulates many biological processes by participating in enzyme catalysis and co-catalysis, including DNA synthesis, cell proliferation, reproduction, development, membrane stability, bone formation, and wound healing. Zinc participates in the composition and regulation of various enzymes and non-enzyme proteins, and is an indispensable component in the animal body for its catalytic, redox, transport, and other biological functions. When an animal's body is deficient or excessive in zinc, it will cause a series of abnormalities in the expression or activity of related enzymes, leading to abnormal metabolism, stunted growth, and even disease in severe cases. In pigeon production, zinc deficiency is mainly prevented by adding inorganic zinc. However, inorganic zinc has disadvantages such as low bioavailability, difficulty in storage, and environmental pollution. Compared with inorganic zinc, organic zinc has a higher bioavailability and function. Commercially available organic zinc for feed includes zinc methionine, zinc glycine, zinc hydroxymethionine, and zinc cysteine. Compared to other organic zincs, cysteamine zinc has advantages such as high zinc content and low price, and has been proven to promote animal growth and development, improve meat quality, enhance immunity, and improve reproductive performance. In pigeon production, how to rationally apply cysteamine zinc to grit has become an important research direction in pigeon farming. Summary of the Invention

[0004] The purpose of this invention is to provide a health care sand containing zinc cysteamine, its preparation method, and its application.

[0005] The technical solution adopted in this invention is: a health care sand containing zinc cysteamine, comprising the following components by weight: 64 parts river sand, 32 parts shell powder, 2 parts a mixture of zinc cysteamine and zeolite powder, and 2 parts premix. The premix provides the following per kilogram of health-promoting grit: Vitamin A, 80,000 IU; Vitamin D3, 34,500 IU; Vitamin E, 480 mg; Vitamin K3, 480 mg; Vitamin B1, 60 mg; Vitamin B2, 217 mg; Vitamin B6, 40 mg; Vitamin B12, 500 µg; Nicotinamide, 300 mg; Folic acid, 11 mg; Pantothenic acid, 150 mg; Biotin, 2.4 mg; Choline chloride, 5,600 mg; Copper, 200 mg; Iron, 1,062 mg; Manganese, 1,100 mg; Iodine, 0.1 mg; Selenium, 0.2 mg.

[0006] As a further optimization of the health care sand containing zinc cysteamine according to the present invention, the weight ratio of zinc cysteamine to zeolite powder is 64:61.

[0007] As a further optimization of the health care sand containing zinc cysteamine according to the present invention, the weight ratio of zinc cysteamine to zeolite powder is 32:93.

[0008] The present invention also provides a method for preparing the above-mentioned health care sand: the mixture of river sand, shell powder, zinc cysteine ​​and zeolite powder and premixed materials in the prescribed amount are mixed and then placed into a sealed bag to obtain the product.

[0009] The present invention also provides the application of the above-mentioned health care grit in pigeon farming. The health care grit is used to increase the average daily weight gain of pigeons, reduce muscle dripping water loss, reduce the crude fat content of the breast muscle, and enhance the antioxidant function of the breast muscle.

[0010] Compared with the prior art, the present invention has the following beneficial effects: I. This invention provides a health grit containing zinc cysteamine, which is applied to the preparation of health grit, providing a new type of health grit for meat pigeons and / or egg pigeons.

[0011] II. This invention applies zinc cysteamine to health grit, which can effectively increase the average daily weight gain of pigeons, shorten the time to market, reduce production costs, and improve the efficiency of pigeon meat production; it can also reduce muscle dripping water loss, reduce the crude fat content of the breast muscle, and enhance the antioxidant function of the breast muscle, effectively improving the nutritional value and sensory quality of pigeon muscle, enhancing its economic value, and meeting people's diversified consumption needs for high-quality livestock and poultry products.

[0012] Third, zinc cysteamine is superior to zinc sulfate at the same concentration in improving the growth, muscle quality, and antioxidant function of pigeons. Using half the concentration of zinc cysteamine can achieve similar effects to zinc sulfate, reducing the use of inorganic zinc and its environmental pollution, and also greatly improving feed nutrient utilization efficiency and reducing feed resource waste. With the rapid development of the pigeon industry towards large-scale and intensive operations, the demand for feed will increase dramatically, which is of great significance for ensuring national feed security and the sustainable development of the pigeon industry. Detailed Implementation

[0013] To further illustrate the present invention, the following detailed description, in conjunction with specific embodiments, illustrates the health-promoting sand containing zinc cysteamine, its preparation method, and its applications. It should be understood that these embodiments are for illustrative purposes only and do not constitute any limitation on the scope of protection of the present invention. Those skilled in the art, after understanding the concept of the present invention, can make reasonable adjustments to the components, proportions, process conditions, etc., and these adjustments also fall within the scope of the present invention.

[0014] Example 1:

[0015] This embodiment provides a health care sand containing zinc cysteamine, which includes the following components by weight: 640g river sand, 320g shell powder, 10.24g zinc cysteamine, 9.76g zeolite powder, and 20g premix.

[0016] The premix (multivitamin and mineral premix) contains the following content per kilogram of health-promoting sand: Vitamin A 80,000 IU, Vitamin D3 34,500 IU, Vitamin E 480 mg, Vitamin K3 480 mg, Vitamin B1 60 mg, Vitamin B2 217 mg, Vitamin B6 40 mg, Vitamin B12 500 µg, Nicotinamide 300 mg, Folic Acid 11 mg, Pantothenic Acid 150 mg, Biotin 2.4 mg, Choline Chloride 5,600 mg, Copper 200 mg, Iron 1,062 mg, Manganese 1,100 mg, Iodine 0.1 mg, and Selenium 0.2 mg.

[0017] Preparation method: Mix the formula amount of river sand, shell powder, zinc cysteamine and zeolite powder and premixed materials evenly, and pack them into sealed bags at a specification of 1kg / bag. The sealed bags will then be used to obtain the health care sand containing zinc cysteamine in this embodiment.

[0018] Example 2:

[0019] This embodiment provides a health care sand containing zinc cysteamine, which includes the following components by weight: 640g river sand, 320g shell powder, 5.12g zinc cysteamine, 14.88g zeolite powder, and 20g premix.

[0020] The premix contains the following components per kilogram of health-promoting sand: Vitamin A 80,000 IU, Vitamin D3 34,500 IU, Vitamin E 480 mg, Vitamin K3 480 mg, Vitamin B1 60 mg, Vitamin B2 217 mg, Vitamin B6 40 mg, Vitamin B12 500 µg, Nicotinamide 300 mg, Folic Acid 11 mg, Pantothenic Acid 150 mg, Biotin 2.4 mg, Choline Chloride 5,600 mg, Copper 200 mg, Iron 1,062 mg, Manganese 1,100 mg, Iodine 0.1 mg, and Selenium 0.2 mg.

[0021] Preparation method: Mix the formula amount of river sand, shell powder, zinc cysteamine and zeolite powder and premixed materials evenly, and pack them into sealed bags at a specification of 1kg / bag. The sealed bags will then be used to obtain the health care sand containing zinc cysteamine in this embodiment.

[0022] In this invention, zinc cysteamine was purchased from Guangzhou Tianke Biotechnology Co., Ltd., and other raw materials were commercially available. The zinc content in zinc cysteamine was 23.44%. Its chemical formula is: C6H 21 O4N3S4Cl2Zn2. This zinc cysteamine is also documented in published literature (literature title: Synthesis and property study of zinc cysteamine complex; author: Wu Chunli).

[0023] Feeding trial: The health-promoting grit containing zinc cysteamine prepared in Examples 1 and 2 was applied to pigeon breeding, and a comparative experiment was conducted to compare its effects. The results are as follows.

[0024] I. Seventy-two pairs of healthy American White King pigeons, aged 24 months and with similar weight and performance, whose incubation period had just ended, were selected. Each pair of pigeons fed three squabs. They were randomly divided into a control group, a zinc sulfate group, a zinc cysteamine group I (Example 1), and a zinc cysteamine group II (Example 2). Each group had six replicates, with three pairs of pigeons and nine squabs per replicate. The control group was fed zinc-free grit, the zinc sulfate group was fed grit containing 2400 mg / kg zinc (zinc sulfate monohydrate), the zinc cysteamine group I was fed grit prepared in Example 1, and the zinc cysteamine group II was fed grit prepared in Example 2. The experiment lasted for 28 days. The composition and content of the grit used in each group are shown in Table 1.

[0025] Table 1. Composition and content of the experimental health-care sand (g / kg)

[0026] The premix (multivitamins and minerals) contains the following content per kilogram of health-promoting sand: Vitamin A 80,000 IU, Vitamin D3 34,500 IU, Vitamin E 480 mg, Vitamin K3 480 mg, Vitamin B1 60 mg, Vitamin B2 217 mg, Vitamin B6 40 mg, Vitamin B12 500 µg, Nicotinamide 300 mg, Folic Acid 11 mg, Pantothenic Acid 150 mg, Biotin 2.4 mg, Choline Chloride 5,600 mg, Copper 200 mg, Iron 1,062 mg, Manganese 1,100 mg, Iodine 0.1 mg, and Selenium 0.2 mg.

[0027] II. Effects of grit on the growth performance of squabs. During the experiment, the body weight of squabs at 1, 7, 14, 21, and 28 days of age was recorded, and the average daily weight gain was calculated. The results are shown in Table 2. Table 2 shows that the average daily weight gain of the zinc cysteine ​​group (group I) from 15 to 21 days was significantly higher than that of the zinc sulfate group. There was no difference between the zinc cysteine ​​group II and the other groups. This indicates that grit containing zinc cysteine ​​can effectively improve the daily weight gain of squabs, shorten the time to market, reduce production costs, and improve the efficiency of squab meat production.

[0028] Table 2 Effects of zinc cysteine ​​on growth performance of pigeons

[0029] III. Effects of grit on pigeon meat quality. At the end of the experiment, samples of breast and leg muscles were collected for subsequent index determination. The pH of the muscle was measured using a pH meter, the brightness, yellowness, and redness of the muscle were measured using a colorimeter, and drip loss was measured using the hanging bag method. The results are shown in Table 3. Table 3 shows that there was no difference in sensory quality between the zinc cysteine ​​group I and the zinc sulfate group. However, the pigeon meat quality, especially drip loss, in the zinc cysteine ​​group II was lower than that of the other experimental groups. This indicates that grit containing zinc cysteine ​​can effectively reduce drip loss, resulting in pigeon meat with good water retention, strong water holding capacity, juicy and tender texture, and high yield.

[0030] Table 3. Effects of zinc cysteamine on the meat quality of squab muscle.

[0031] IV. Effects of grit on the nutritional composition of pigeon breast muscle. The crude protein, crude fat, and crude ash contents of breast muscle were determined using the Kjeldahl method, petroleum ether extraction method, and ignition method, respectively. The results are shown in Table 4. Table 4 shows that the crude fat content of the zinc cysteine ​​group I was lower than that of the zinc cysteine ​​group II. There was no difference between the zinc cysteine ​​group II and the control group and the zinc sulfate group. This indicates that grit containing zinc cysteine ​​can reduce the crude fat content of breast muscle and improve meat quality.

[0032] Table 4. Effects of cysteine ​​zinc on the nutritional composition of squab breast muscle (based on freeze-dried meat)

[0033] V. Effects of grit on the antioxidant function of pigeon muscle. The activities of total superoxide dismutase (T-SOD), catalase (CAT), glutathione (GSH), and malondialdehyde (MDA) in muscle were measured using reagent kits. All antioxidant-related reagent kits were purchased from Nanjing Jiancheng Bioengineering Research Institute Co., Ltd. The results are shown in Table 5. Table 5 shows that, compared with the control group, both zinc sulfate and zinc cysteine ​​enhanced muscle antioxidant capacity and reduced oxidative stress. Furthermore, the zinc cysteine ​​group I showed a better antioxidant effect than the zinc sulfate group, while the effect of the zinc cysteine ​​group II was comparable to that of the zinc sulfate group. This indicates that grit containing zinc cysteine ​​can enhance muscle antioxidant capacity and reduce oxidative stress.

[0034] Table 5. Effects of zinc cysteine ​​on the antioxidant function of squab muscle

[0035] In conclusion, health grit containing zinc cysteine ​​can effectively increase the average daily weight gain of pigeons, reduce muscle dripping water loss, reduce the crude fat content of breast muscles, and enhance the antioxidant function of breast muscles. This not only improves the production efficiency of pigeon meat but also effectively enhances the nutritional value and sensory quality of pigeon muscle, thereby increasing its economic value and meeting people's diversified consumption demands for high-quality livestock and poultry products.

[0036] The specific embodiments of the present invention have been described above. It should be understood that the present invention is not limited to the specific embodiments described above, and those skilled in the art can make various modifications or variations within the scope of the claims, which do not affect the essence of the present invention.

Claims

1. A health-promoting sand containing zinc cysteamine, characterized in that, The composition includes the following components by weight: 64 parts river sand, 32 parts shell powder, 2 parts a mixture of zinc cysteine ​​and zeolite powder, and 2 parts premix. The premix provides the following per kilogram of health-promoting grit: Vitamin A, 80,000 IU; Vitamin D3, 34,500 IU; Vitamin E, 480 mg; Vitamin K3, 480 mg; Vitamin B1, 60 mg; Vitamin B2, 217 mg; Vitamin B6, 40 mg; Vitamin B12, 500 µg; Nicotinamide, 300 mg; Folic acid, 11 mg; Pantothenic acid, 150 mg; Biotin, 2.4 mg. Choline chloride, 5600 mg; copper, 200 mg; iron, 1062 mg; manganese, 1100 mg; iodine, 0.1 mg; selenium, 0.2 mg.

2. The health care sand containing zinc cysteamine according to claim 1, characterized in that: The weight ratio of zinc cysteamine to zeolite powder is 64:

61.

3. The health care sand containing zinc cysteamine according to claim 1, characterized in that: The weight ratio of zinc cysteamine to zeolite powder is 32:

93.

4. The method for preparing the health care sand containing zinc cysteamine as described in any one of claims 1-3, characterized in that, Mix the prescribed amounts of river sand, shell powder, zinc cysteine, and zeolite powder with the premixed material, and after mixing evenly, pack the mixture into a sealed bag to obtain the final product.

5. The application of the zinc cysteamine-containing health grit as described in any one of claims 1-3 in pigeon farming, wherein the health grit is used to increase the average daily weight gain of pigeons, reduce muscle dripping water loss, reduce the crude fat content of the pectoral muscles, and enhance the antioxidant function of the pectoral muscles.

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