A traditional Chinese medicine composition for treating throat and oral cavity diseases

Abstract

The present application relates to a kind of traditional Chinese medicine composition for treating throat oral cavity disease, can effectively prevent and treat oral ulcer, tonsil inflammation, gum swelling and pain, throat swelling and pain.It is made of the following weight parts of raw medicinal materials: ox gall, raw gypsum, licorice, borneol, borax, pearl, greenish blue, Huangqi, Andrographis Herba, Huangbai, alum, talcum powder, dragon's blood, catechu, anhydrous sodium sulfate, cantharides, Sichuan motherwort, mint leaf, gizzard gold.The traditional Chinese medicine prescription in the present application is properly matched, has good curative effect, small side effect, simple preparation, safe and reliable, and has good application value.

Description

Technical Field

[0001] This invention relates to the field of medicine, and in particular to a traditional Chinese medicine powder composition for treating oral and pharyngeal diseases. Background Technology

[0002] Currently, most traditional Chinese medicine products on the market for the prevention and treatment of oral and throat diseases are based on heat-clearing and detoxifying powders. However, with the continuous improvement of modern living conditions, oral and throat problems are now more commonly caused by excessive intake of heat-inducing foods or rapid climate changes, leading to a higher incidence of oral ulcers, sore throats, and tonsillitis. Therefore, finding a highly effective traditional Chinese medicine powder for the prevention and treatment of oral and throat diseases that is palatable and suitable for modern people is an urgent problem to be solved.

[0003] The oral cavity, located in the maxillofacial region, includes biological organs such as teeth, jawbone, lips, cheeks, palate, and tongue. As the starting point of the digestive system, the oral cavity performs various physiological functions including chewing, swallowing, speech, sensation, and respiration. Its structural features (teeth, tongue, salivary glands, etc.) collectively support these functions. The oral cavity is considered a central part of the body, preferring warmth rather than extreme heat. Yin or Yang deficiency can lead to internal heat that affects the heart, directly manifesting as swollen and painful gums and oral ulcers. The pharynx, located at the junction of the oral cavity with the esophagus and trachea, comprises key parts such as the nasopharynx, oropharynx, and laryngopharynx. The oropharynx contains the tonsils, which are part of the human immune system, primarily responsible for recognizing and defending against invading pathogens.

[0004] Oral ulcers fall under the categories of "oral sores," "oral erosion," and "oral ulcers" in Traditional Chinese Medicine (TCM). TCM believes that the occurrence of oral ulcers is related to multiple factors, with the core pathogenesis often involving upward flaring of heat or upward floating of deficient fire, leading to malnourishment and ulceration of the oral mucosa. Common causes and mechanisms include: 1. Accumulation of heat in the heart and spleen: Spicy and stimulating foods, emotional distress, etc., lead to the accumulation of internal heat in the heart and spleen, which rises to the oral cavity, scorching the mucosa and causing the disease. Ulcers are often characterized by significant redness, swelling, and pain, accompanied by symptoms such as dry mouth and constipation. 2. Yin deficiency with exuberant fire: Long-term sleep deprivation, overwork, or a yin deficiency constitution lead to insufficient yin fluid and internal generation of deficient fire, which then disturbs the oral cavity. Ulcers often recur, with milder pain, and are often accompanied by hot palms and soles, night sweats, and hot flashes. 3. Weakness of the spleen and stomach: Dysfunction of the spleen and stomach leads to insufficient production of qi and blood, resulting in malnourishment of the oral mucosa, making it susceptible to external pathogens and causing ulcers. Ulcers are pale in color, with mild pain, and are often accompanied by loss of appetite and loose stools.

[0005] Swollen and painful gums fall under the categories of "tooth abscess," "tooth carbuncle," and "tooth bleeding" in Traditional Chinese Medicine (TCM), with "tooth carbuncle" specifically describing an acute attack of significant redness, swelling, and pain in the gums. TCM believes that the core pathogenesis of swollen and painful gums is often related to "heat," either due to excessive heat or upward flaring of deficient fire, and frequently involves dysfunction of the spleen, stomach, and kidneys. Common causes and mechanisms include: First, excessive stomach fire. Spicy and greasy foods, excessive alcohol consumption, etc., lead to internal generation of stomach fire, which then ascends along the meridians to flare up in the gums. This manifests as severe redness, swelling, and pain in the gums, possibly accompanied by halitosis, dry mouth, constipation, and other symptoms. Secondly, kidney yin deficiency leading to upward flaring of deficient fire. Prolonged periods of staying up late, overwork, or a constitution with yin deficiency can cause kidney yin deficiency, resulting in upward flaring of deficient fire that erodes the gums. Symptoms often include dull gum pain and mild swelling, but these symptoms tend to recur, frequently accompanied by hot palms and soles, and lower back and knee weakness. Thirdly, wind-heat invasion. External wind-heat pathogens invade the gums along the meridians, causing stagnation of qi and blood. This often presents with an acute onset, characterized by red, swollen, and painful gums, possibly accompanied by fever, sore throat, and other superficial symptoms.

[0006] Tonsillitis falls under the category of "rough tonsillitis" in Traditional Chinese Medicine (TCM). Unilateral tonsillitis is called "single rough tonsillitis," while bilateral tonsillitis is called "double rough tonsillitis." If the tonsils are red, swollen, and suppurating, it is often classified as "rotten rough tonsillitis." TCM believes that the core pathogenesis of tonsillitis is the invasion of heat toxins into the throat, leading to stagnation of qi and blood, and obstruction of the meridians, or recurrence due to deficiency of the internal organs and upward flaring of deficient fire. Common causes and mechanisms include: First, external invasion of wind-heat: External wind-heat pathogens enter through the mouth and nose, invading the throat, causing redness, swelling, and pain in the tonsils. This often has an acute onset, accompanied by fever, slight aversion to wind and cold, and dry throat. Second, excessive heat in the lungs and stomach: Spicy food, emotional distress, etc., lead to the accumulation of internal heat in the lungs and stomach, which then attacks the throat, exacerbating the redness and swelling of the tonsils, and even causing suppuration. It is often accompanied by symptoms such as high fever, bad breath, thirst, and constipation; thirdly, it is due to lung and kidney yin deficiency: long-term staying up late, overwork, or prolonged illness can lead to insufficient lung and kidney yin fluid, resulting in internal heat that rises to the throat. It often manifests as recurrent mild redness and swelling of the tonsils, dull pain, accompanied by symptoms such as dry and itchy throat, and hot palms and soles.

[0007] Sore throat falls under the category of "throat obstruction" in Traditional Chinese Medicine (TCM). If the pain is severe, and there are pustules or ulcers in the throat, it may also be classified as "throat carbuncle." Both are characterized by redness, swelling, and pain in the throat. TCM believes that the core pathogenesis of sore throat is "excessive heat toxin" or "upward flaring of deficient fire," leading to poor blood and qi circulation and blocked meridians in the throat. It is also closely related to dysfunction of the lungs, stomach, and kidneys. Common causes and mechanisms include: First, external wind-heat invasion. External wind-heat pathogens invade through the mouth and nose, first affecting the throat. Symptoms include redness, swelling, and pain in the throat, discomfort when swallowing, often accompanied by fever, slight aversion to wind, nasal congestion, and yellow nasal discharge. Second, excessive heat in the lungs and stomach. Spicy and greasy food, excessive alcohol consumption, or emotional distress lead to the accumulation of internal heat in the lungs and stomach, which then ascends to the throat. Severe throat pain may be accompanied by bad breath, thirst with a preference for cold drinks, constipation, and yellow urine. Third, lung and kidney yin deficiency. Prolonged periods of staying up late, overwork, or chronic illness deplete yin fluids, leading to lung and kidney yin deficiency and internal heat, which then disturbs the throat. Symptoms include a dull, dry, and uncomfortable throat that is prone to recurrence, often accompanied by hot palms and soles, dry cough with little phlegm, and weakness in the lower back and knees.

[0008] Existing technology (Double-Ingredient Throat Powder): Contains artificial bezoar, borneol, Coptis chinensis, pearl, licorice, Sophora tonkinensis root, indigo naturalis, calcined human placenta, and gypsum, etc., which has a certain therapeutic effect on throat diseases, but has drawbacks such as unsatisfactory efficacy, bitter taste, and difficulty in patient tolerance. It also has adverse effects on pregnant women and children, and because Sophora tonkinensis root is toxic, excessive use can lead to nausea and vomiting. Human placenta should be used with caution by those with spleen and stomach deficiency and diarrhea. Gypsum is relatively safe, but long-term use can lead to elevated blood calcium levels, increasing the risk of kidney stones, or causing digestive system risks such as nausea and bloating. Summary of the Invention

[0009] In view of the above situation and to solve the problems existing in the prior art, the purpose of this invention is to provide a traditional Chinese medicine composition for the prevention and treatment of oral and pharyngeal diseases. It has good efficacy, fast onset of action, high cure rate, low recurrence rate, few side effects, and is convenient to take. It can be used for the prevention and early treatment of oral ulcers, gingival swelling and pain, tonsillitis, and sore throat.

[0010] This invention strictly follows the principles of traditional Chinese medicine prescription. In the formulation of Chinese medicine prescriptions, the principal drug and the assistant drug are the core components. Together, they ensure the core efficacy of the prescription and follow the compatibility logic of traditional Chinese medicine.

[0011] To achieve the above objectives, the technical solution provided by this invention is: a traditional Chinese medicine powder for the prevention and treatment of oral diseases, made from the following raw materials and processes in parts by weight: (I) Ingredients of Combination Drug I: Pearl 1-3 parts, bezoar 1-3 parts, borneol 3-5 parts, alum 8-10 parts, borax 8-10 parts, catechu 4-6 parts, licorice 7-9 parts, talc 40-60 parts.

[0012] (II) Components of Combination Drug II: 3-5 parts of silkworm, 4-6 parts of fritillaria cirrhosa, 3-5 parts of indigo naturalis, 4-6 parts of phellodendron bark, 4-6 parts of andrographis paniculata, 3-5 parts of peppermint leaf, 4-6 parts of scutellaria baicalensis, 4-6 parts of sodium sulfate, 2-4 parts of dragon's blood, 14-16 parts of gypsum, 11-13 parts of borax, 7-9 parts of licorice, and 2-4 parts of chicken gizzard lining.

[0013] (III) Specific pharmaceutical manufacturing steps: Step 1: Prepare the combination medicine according to the specified weight proportions. Strictly select various Chinese medicinal materials, clean each material thoroughly, grind them into powder, and dry them. First, mix and dry the catechu and borax. Second, dry the alum separately. Third, mix and dry the licorice and talc. Fourth, grind and dry the bezoar, pearl, and borneol. Fifth, after the above four batches of dried medicinal powder are stored in a dry environment for 2 days, filter them through a 120-mesh sieve, mix them together, and then immediately seal them in a container for 3-5 days.

[0014] Step Two: Prepare the second combination of medicines according to the specified weight proportions. Strictly select various Chinese medicinal materials, clean each material thoroughly, mix and grind them into powder, and immediately seal the mixed powder in a container while the materials are still warm, storing it for 3-5 days.

[0015] Step 3: Select combination drug 2 at approximately 10% of the proportion of combination drug 1, and mix it evenly with the powder made from combination drug 1 to obtain the Chinese herbal medicine mixed powder.

[0016] Step 4: After the powder is made, let it air dry for one day, seal it in a bottle or jar, and keep it dry.

[0017] Bezoar: A precious traditional Chinese medicine, its core functions are clearing the heart, resolving phlegm, opening the orifices, cooling the liver, calming wind, and detoxifying. Its main functions are: first, clearing heat and detoxifying, reducing swelling and soothing the throat, directly targeting the heat toxins in the throat area, quickly relieving symptoms of redness, swelling, and burning pain in the throat; second, it has a detoxifying and anti-inflammatory effect on suppuration and swelling caused by tonsillitis; third, when combined with pearl, borneol, etc., it enhances the overall effects of clearing heat and detoxifying, and repairing the mucous membranes.

[0018] Gypsum (Solid Gypsum) is a commonly used mineral-based traditional Chinese medicine. It is cold in nature and sweet and pungent in taste. It has the effects of clearing heat and purging fire, relieving irritability and quenching thirst, promoting body fluid production and moistening dryness, and relieving muscle tension and expelling pathogens. It is widely used in heat-clearing formulas. Its main functions are: 1. Clearing heat and purging fire, relieving sore throat: Gypsum can clear excess heat in the Qi level, significantly improving redness, burning, and pain in the throat caused by excessive heat toxins. It is suitable for acute pharyngitis, tonsillitis, etc.; 2. Promoting body fluid production and moistening dryness, improving dry throat: It has an auxiliary effect on improving dry throat, sore throat, and throat discomfort caused by excessive heat damaging body fluids; 3. Assisting in detoxification and enhancing heat-clearing effects: When combined with heat-clearing and detoxifying drugs such as bezoar and borax, it can enhance the overall heat-clearing, detoxifying, and swelling-reducing effects of the formula; 4. Reducing congestion of the throat mucosa: The heat-clearing effect of gypsum can reduce congestion and edema of the throat mucosa, improving difficulty swallowing.

[0019] Licorice: One of the most commonly used Chinese herbs, it is neutral in nature and sweet in taste. It has the effects of invigorating qi and nourishing the middle jiao, clearing heat and detoxifying, harmonizing other herbs, relieving pain, and moistening the lungs and relieving cough. It is almost ubiquitous in various prescriptions and is known as the "national elder." Its main functions are: 1. Clearing heat and detoxifying, relieving sore throat and pain. Licorice clears heat and detoxifies, reducing redness and swelling of the throat and pain, suitable for acute pharyngitis, tonsillitis, etc.; 2. Harmonizing other herbs, reducing irritation. Throat powder often contains strong or highly irritating herbs such as bezoar, borneol, and borax. Licorice can moderate their potency, making the formula milder and reducing irritation to the throat mucosa; 3. Moistening the lungs and promoting body fluids, improving dry and itchy throat. It has an auxiliary effect in improving dry throat, foreign body sensation, and irritating cough; 4. Enhancing overall efficacy. When combined with bezoar, borneol, borax, etc., licorice can enhance the effects of clearing heat and detoxifying, reducing swelling and relieving sore throat, improving the overall therapeutic effect of the prescription, and is one of the principal herbs in this formula.

[0020] Borneol: A natural crystalline compound extracted from the resin of the Dipterocarpus santalinus tree (a plant in the Dipterocarpaceae family). It is a precious aromatic and orifice-opening traditional Chinese medicine, with core functions of opening the orifices and refreshing the mind, clearing heat and relieving pain, and preventing decay and promoting tissue regeneration. Its main functions are: 1. Quickly relieving sore throat: Its pungent and cooling properties can directly act on the throat mucosa, rapidly reducing redness, swelling, heat, and pain, and improving symptoms of swallowing discomfort; 2. Enhancing the heat-clearing and detoxifying effects: Its pungent and penetrating properties can guide the medicinal power of pearl, bezoar, and other herbs directly to the affected area of ​​the throat, enhancing the overall heat-clearing and detoxifying effect of the formula; 3. Repairing damaged throat mucosa: Its antiseptic and tissue-regenerating effects can promote the repair of inflamed and eroded throat and tonsil mucosa, reducing ulcer recurrence.

[0021] Borax: (medicinal borax) is a commonly used mineral Chinese medicine, cool in nature, sweet and salty in taste, with the main effects of clearing heat and detoxifying, reducing swelling and preventing corrosion, and resolving phlegm. The main functions are as follows: First, to enhance the effect of clearing heat and detoxifying. When combined with bezoar, borneol, and pearls, it can enhance the clearing effect of the whole prescription on throat heat toxins and improve the curative effect on acute pharyngitis and tonsillitis. Second, to quickly relieve throat swelling and pain. Its salty and cool nature can directly act on the throat mucosa, reducing redness, swelling, heat, and pain. Third, to promote the healing of eroded mucosa. It has a good repairing effect on throat erosion and oral ulcers, can reduce secretions, and promote the healing of the wound surface.

[0022] Pearl: It is a precious medicinal material in traditional Chinese medicine. Its core effects are calming the mind and relieving uneasiness, removing nebula and improving eyesight, detoxifying and promoting granulation, and moistening the skin and removing freckles. The main functions are as follows: First, the functions of detoxifying and promoting granulation, clearing heat and reducing swelling. Second, to relieve the redness, swelling, pain, and damage of the throat mucosa. Third, to promote the repair of the inflamed throat / tonsil mucosa, reducing the healing time of ulcers and erosions. Fourth, to assist in clearing heat and detoxifying, enhancing the therapeutic effect of the preparation on throat inflammation.

[0023] Indigo Naturalis: It is a commonly used Chinese medicine for clearing heat and detoxifying, cold in nature, salty in taste, with the effects of clearing heat and detoxifying, cooling blood and eliminating macules, purging fire and calming fright, etc., and is widely used in diseases such as heat-toxin macules, throat swelling and pain, oral ulcers, and mumps. The main functions are as follows: First, to clear heat and detoxify, relieve the redness, swelling, heat, and pain of the throat. Indigo Naturalis is cold in nature and can clear the heat toxins in the throat, and has an obvious improvement effect on acute pharyngitis, tonsillitis, and the redness, swelling, heat, and pain of the throat. Second, to cool blood and reduce swelling, relieve pharyngeal congestion. It has the effect of cooling blood and reducing swelling on the congestion and bleeding points of the throat mucosa caused by heat damaging collaterals. Third, to assist in promoting the healing of eroded mucosa. After being combined with catechu, pearl, borax and other drugs, it can enhance the effects of detoxifying, astringing, and promoting granulation, and promote the healing of throat erosion and ulcers. Fourth, to improve oral ulcers and gum swelling and pain. Indigo Naturalis has a good effect on clearing the heat toxins of the oral mucosa and can be used for oral ulcers, gum swelling and pain, etc.

[0024] Scutellaria baicalensis: It is a commonly used Chinese medicine for clearing heat and drying dampness, cold in nature, bitter in taste, with the effects of clearing heat and drying dampness, purging fire and detoxifying, stopping bleeding, and preventing miscarriage, etc., and is widely used in heat-clearing prescriptions. The main functions are as follows: First, to clear heat and detoxify, relieve the redness, swelling, heat, and pain of the throat. Scutellaria baicalensis is bitter and cold, can clear the heat of the lung and stomach, and has an obvious improvement effect on the redness, swelling, heat, and pain caused by heat-toxin congestion in the throat, and is suitable for acute pharyngitis, tonsillitis, etc. Second, to clear heat and dry dampness, reduce secretions. For patients with heavy dampness and heat in the throat and more secretions, Scutellaria baicalensis can dry dampness and clear heat, reduce phlegm and purulent secretions, and improve discomfort in the throat. Third, to assist in reducing swelling and enhancing the overall therapeutic effect. After being combined with bezoar, borax, borneol and other heat-clearing and detoxifying drugs, it can enhance the heat-clearing, detoxifying, and swelling-reducing effects of the whole prescription and improve the therapeutic effect on throat inflammation. Fourth, to relieve symptoms such as cough and dry throat.

[0025] Andrographis paniculata: Clears heat and detoxifies, cools the blood, and reduces swelling. Used for colds with fever, sore throat, mouth ulcers, persistent cough, diarrhea, dysentery, painful urination, carbuncles, sores, and snake and insect bites. Its main functions are: 1. Clears heat and detoxifies, relieving redness, swelling, heat, and pain in the throat. Its bitter and cold nature can clear heat from the heart and stomach, significantly improving redness, burning, and pain in the throat caused by excessive heat or fire. 2. Assists in reducing swelling and enhances overall efficacy. When combined with heat-clearing and detoxifying drugs such as bezoar, borax, and borneol, it can enhance the overall heat-clearing, detoxifying, and swelling-reducing effects of the formula, improving the treatment effect on throat inflammation. 3. Improves mouth ulcers and oral sores, working synergistically with drugs such as indigo naturalis and catechu.

[0026] Phellodendron bark: A commonly used Chinese herbal medicine for clearing heat and drying dampness. It is cold in nature and bitter in taste. It has the effects of clearing heat and drying dampness, purging fire and detoxifying, reducing fever and eliminating steaming. It is widely used in the treatment of damp-heat diseases and various infectious diseases. Its main functions are: First, to clear heat and detoxify, relieving redness, swelling, heat, and pain in the throat. Phellodendron bark is bitter and cold, clearing heat and toxins, significantly improving redness, swelling, burning, and pain in the throat caused by heat toxins or damp-heat accumulation. It is suitable for acute pharyngitis, tonsillitis, etc. Second, to clear heat and dry dampness, reducing secretions. For patients with severe damp-heat in the throat and excessive secretions, Phellodendron bark can dry dampness and clear heat, reducing phlegm and purulent secretions, and improving throat discomfort. Third, to assist in reducing swelling and enhance overall efficacy. When combined with heat-clearing and detoxifying drugs such as bezoar, borax, and borneol, it can enhance the heat-clearing, detoxifying, and swelling-reducing effects of the whole formula, improving the treatment effect on throat inflammation. Fourth, to alleviate throat itching and burning sensation. The heat-clearing and dampness-drying effects of Phellodendron bark can relieve symptoms such as throat itching and burning caused by damp-heat.

[0027] Alum (also known as white alum) is a commonly used mineral-based traditional Chinese medicine. After calcination, it becomes calcined alum. Its core functions are: external application for detoxification and insecticidal effects, drying dampness and relieving itching; and internal application for hemostasis, diarrhea, and phlegm removal. Its main functions are: first, astringent and hemostatic, quickly closing wounds, stopping bleeding, and relieving pain in cases of congestion and erosion of the pharyngeal mucosa with minor bleeding; second, enhancing anti-swelling effects, its drying and astringent properties can reduce edema of the pharyngeal mucosa and improve swallowing difficulties; and third, auxiliary antibacterial effect, having a certain inhibitory effect on pathogens causing pharyngitis and tonsillitis, forming a synergistic antibacterial effect with pearl, bezoar, etc.

[0028] Talc powder is a commonly used mineral-based traditional Chinese medicine. It is cold in nature and sweet and bland in taste. Its main functions are to promote urination, clear heat and relieve summer heat, and dispel dampness and astringe sores. Its main effects are: 1. Clearing heat and removing dampness, and assisting in detoxification. Talc powder, being cold in nature, can clear heat and promote diuresis, and can help improve sore throat and sticky mouth caused by damp-heat stagnation; 2. Astringent and drying, reducing secretions. For patients with congestion and excessive exudation of the throat mucosa, talc powder can astringe and dry, reducing purulent secretions and improving throat discomfort; 3. Protecting the throat mucosa. Talc powder is fine and smooth, and can form a protective film on the surface of the throat mucosa, reducing irritation and relieving pain; 4. As a carrier, facilitating administration via throat blowing. In traditional throat blowing medications, talc powder is often used as a matrix or diluent to make the drug powder finer, easier to disperse, and improve the uniformity of administration.

[0029] Dragon's blood has the effects of promoting blood circulation and removing blood stasis, relieving pain, stopping bleeding and promoting tissue regeneration, and astringing sores, which enhances the overall effect of the formula in promoting blood circulation, relieving pain and astringing sores.

[0030] Catechu (also known as catechu or wudie ni) is a commonly used traditional Chinese medicine for clearing heat and detoxifying, and astringing and healing sores. It is widely used in otolaryngology, dermatology, and proctology. Its main functions are: 1. Clearing heat and detoxifying, reducing swelling and relieving pain: Catechu is cold in nature and can clear heat toxins from the throat, reducing redness, swelling, and pain. When combined with bezoar and borax, it can enhance the heat-clearing and detoxifying effect. 2. Astringing the throat mucosa and reducing secretions: For patients with significant throat mucosal congestion, erosion, and exudation, catechu can quickly astringe the wound, reduce purulent secretions, and improve throat discomfort. 3. Promoting the healing of erosions and ulcers: The astringent and tissue-regenerating effects of catechu can accelerate the healing of damaged throat mucosa, especially suitable for chronic pharyngitis and recurrent oral ulcers. 4. Assisting in improving dry and itchy throat: Catechu also has a saliva-generating effect, which can relieve throat dryness and a foreign body sensation.

[0031] Sodium sulfate (also known as mirabilite or weathered sodium sulfate) is anhydrous sodium sulfate obtained by weathering sodium sulfate and losing its water of crystallization. It is cold in nature and has a salty and bitter taste. It has the effects of purging heat and relieving constipation, moistening dryness and softening hardness, clearing heat and reducing swelling. It is widely used in purgative and heat-clearing prescriptions. Its main functions are: First, to clear heat and purge fire, relieving redness, swelling, heat, and pain in the throat. Sodium sulfate is cold in nature and can clear heat toxins, providing auxiliary relief for redness, swelling, burning, and pain in the throat caused by excessive heat or heat toxins. It is suitable for acute pharyngitis, tonsillitis, etc. Second, to reduce swelling and dissipate nodules, alleviating throat swelling. Its salty and cold nature can soften and dissipate nodules, reducing throat swelling and improving difficulty swallowing. Third, to assist in clearing heat and detoxifying, enhancing overall efficacy. When combined with heat-clearing and detoxifying drugs such as bezoar, borax, and borneol, it can enhance the heat-clearing, detoxifying, and swelling-reducing effects of the whole formula, improving the treatment effect on throat inflammation. Fourth, to improve dryness and burning sensation in the throat. The moisturizing effect of sodium sulfate can relieve symptoms such as dry throat caused by excessive heat damaging body fluids.

[0032] Fritillaria cirrhosa (also known as Fritillaria cirrhosa bulb) is a precious traditional Chinese medicine for resolving phlegm and relieving cough. It is slightly cold in nature and has a sweet and bitter taste. It possesses the effects of clearing heat and moistening the lungs, resolving phlegm and relieving cough, and dispersing nodules and reducing swelling. It is widely used in respiratory and laryngeal prescriptions. Its main functions are: 1. Moistening the lungs and relieving cough, alleviating dry and itchy throat: Fritillaria cirrhosa can moisturize the throat mucosa and improve symptoms such as dry throat, itchy throat, and irritating cough, making it suitable for those with chronic pharyngitis and dry throat; 2. Resolving phlegm and dispersing nodules, assisting in reducing swelling: It has an auxiliary effect in improving swelling and foreign body sensation in the throat caused by phlegm-heat stagnation, and can be combined with bezoar, borax, etc., to enhance the effect of clearing heat and resolving phlegm; 3. Relieving throat pain caused by cough: Fritillaria cirrhosa can reduce the frequency and intensity of cough, thereby reducing the stimulation of the throat mucosa by cough and relieving secondary throat pain; 4. Assisting in improving dry and damaged pharyngeal mucosa: Its lung-moistening effect can improve dry and slightly damaged pharyngeal mucosa and enhance local resistance. Combined with bezoar, it can enhance the effects of clearing heat and resolving phlegm, reducing swelling and relieving sore throat; combined with borneol, it can improve sore throat and burning sensation, and enhance local therapeutic effects; combined with borax, it can synergistically clear heat, resolve phlegm, and promote mucosal repair; combined with catechu, it can jointly promote mucosal healing and is suitable for dry throat, sore throat, and mild erosion. Combined with licorice, it enhances the effects of moisturizing the lungs and relieving cough, and harmonizing the properties of other herbs.

[0033] Silkworm (also known as silkworm or white silkworm) is a commonly used traditional Chinese medicine for dispelling wind and relieving spasms. It is neutral in nature and has a pungent and salty taste. It has the effects of dispelling wind and relieving spasms, resolving phlegm and dissipating nodules, detoxifying and relieving sore throat. It is widely used in diseases such as wind-phlegm obstruction, sore throat, canker sores, and itchy rashes. Its main functions are: First, to dispel wind and resolve phlegm, relieving sore throat. Silkworm can dispel wind and resolve phlegm, disperse nodules and reduce swelling, and has an auxiliary effect on improving sore throat and foreign body sensation in the throat caused by wind-phlegm disturbance or phlegm-dampness stagnation. Second, to help reduce swelling and improve the feeling of lumps in the throat. It has a certain effect on dispersing swelling and lymphoid follicle hyperplasia in the throat caused by phlegm-dampness. Third, to detoxify and soothe the throat, improving oral ulcers and pharyngeal erosion. When combined with drugs such as indigo naturalis, catechu, and borax, it can enhance the effects of detoxification, astringency, and tissue regeneration, and promote the healing of pharyngeal erosion and ulcers. Fourth, to improve hoarseness, itchy throat and cough. Silkworm can dispel wind and resolve phlegm, and has a certain effect on relieving hoarseness, itchy throat and cough caused by wind-phlegm obstructing the throat.

[0034] Peppermint leaves: are a commonly used traditional Chinese medicine for dispersing wind-heat. They are cool in nature and pungent in taste. They have the effects of dispersing wind-heat, clearing the head and eyes, relieving sore throat and promoting rash eruption, and soothing the liver and regulating qi. They are widely used in wind-heat colds, throat diseases, headaches, red eyes and other symptoms. Its main functions are: First, to dispel wind-heat and relieve sore throat redness, swelling, heat and pain. Peppermint leaves are cool in nature and can clear away wind-heat evil in the throat. They have a significant effect on improving sore throat redness, swelling, burning and pain caused by wind-heat attack or heat toxicity. They are suitable for acute pharyngitis, tonsillitis, etc. Second, to clear the throat and improve hoarseness. Its pungent and cool nature can reduce the inflammatory reaction in the throat and relieve hoarseness and throat discomfort. Third, to assist in reducing swelling and enhance the overall efficacy. When combined with heat-clearing and detoxifying drugs such as bezoar, borax, and borneol, it can enhance the heat-clearing, detoxifying and swelling-reducing effects of the whole prescription and improve the treatment effect on throat inflammation. Fourth, to improve throat itching and foreign body sensation. Peppermint leaves can dispel wind and heat and have a certain relieving effect on throat itching and foreign body sensation caused by wind-heat.

[0035] Chicken gizzard lining: A commonly used traditional Chinese medicine for digestion, it is neutral in nature and sweet in taste. It has the effects of strengthening the stomach and promoting digestion, astringing essence and stopping seminal emission, and clearing urinary tract stones. It is widely used in gastroenterology and urology. Its main functions are as follows: First, it strengthens the spleen and aids digestion, helping to improve throat inflammation. Those with weak spleen and stomach, and impaired digestion, are prone to phlegm and dampness, which can cause throat discomfort, excessive phlegm, and a foreign body sensation. Chicken gizzard lining can strengthen the spleen and promote digestion, aiding digestion and resolving phlegm, thereby improving throat symptoms. Second, it resolves phlegm and dissipates nodules, helping to reduce swelling. It has a certain auxiliary effect in improving throat swelling and a foreign body sensation caused by phlegm and dampness accumulation. Third, it enhances the overall therapeutic effect. When combined with heat-clearing and detoxifying drugs such as bezoar, borax, and borneol, it can improve the overall therapeutic effect of the formula by strengthening the spleen, resolving phlegm, and improving the constitution.

[0036] Overall, this formula uses bezoar, gypsum, and licorice as the principal ingredients to clear heat and detoxify. Borneol, borax, pearl, and indigo are used as assistant ingredients to enhance the heat-clearing and detoxifying effects. Scutellaria baicalensis, andrographis paniculata, and phellodendron amurense are also assistant ingredients to clear damp-heat in the triple burner and cut off the source of heat in the throat and mouth, thereby improving the efficacy of the principal ingredients. Alum, talc, dragon's blood, catechu, sodium sulfate, silkworm pupae, fritillaria cirrhosa, peppermint leaves, and chicken gizzard lining are used as adjuvant ingredients to target oral and throat symptoms. Alum, talc, dragon's blood, and catechu mainly assist in astringing sores, while sodium sulfate assists in reducing swelling. In the later stages of treatment, silkworm pupae and fritillaria cirrhosa are used to resolve phlegm and eliminate throat symptoms, while peppermint leaves assist in soothing the throat and quickly relieve throat discomfort during the acute phase. Chicken gizzard lining assists in strengthening the spleen and promoting digestion, indirectly improving phlegm-dampness symptoms.

[0037] This formula conforms to the principles of traditional Chinese medicine prescriptions. It can not only quickly eliminate inflammation, but also relieve cough and phlegm, achieving the goal of treating both the symptoms and the root cause. It has the effects of clearing heat and detoxifying, reducing inflammation and relieving pain, and has special efficacy for pharyngitis and tonsillitis. Compared with Shuangliao Houfengsan, this medicine has a milder smell, a crystal-white color, and is not bitter when taken. It is more effective, does not harm the liver, and rarely causes allergic reactions when applied to the skin. Detailed Implementation

[0038] This invention has broad application prospects and has been fully proven through long-term clinical application. Specific experimental data are as follows: We collected data on medication use from January 2019 to December 2022 and followed up with 315 cases. The improvement of sore throat, tonsillitis, and oral ulcers was statistically analyzed, and the results are shown in Tables 1-2.

[0039] Improvement rate = 1 - Number of cases after treatment / Number of cases before treatment Table 1. Statistical table of symptom improvement before and after treatment Based on the diagnostic criteria of Traditional Chinese Medicine (TCM), the important symptoms and signs of the primary and secondary symptoms in each syndrome were observed. These mainly included the following symptom indicators: presence of pain, presence of redness and swelling, presence of phlegm, dry mouth, and sleep patterns. Clinical symptoms were classified into four levels: disappearance, improvement, ineffectiveness, and worsening. The overall effective rate was calculated.

[0040] Effectiveness rate = (Number of cases with symptom disappearance + Number of cases with symptom improvement) / Total number of cases Table 2 Statistical Table of Disease Treatment Results The above data shows that this invention significantly improves symptoms such as sore throat, oral ulcers, and tonsillitis, particularly in patients with oral ulcers, achieving a total effective rate of 91.3%. This demonstrates the invention's excellent therapeutic effect and satisfactory clinical results. No adverse reactions were observed in clinical trials. This invention is remarkably effective in treating oral ulcers, achieving an effective rate of 91.3%. It boasts advantages such as high efficacy, safety, simple preparation, and minimal formulation requirements, making it highly valuable for clinical application.

Claims

1. A traditional Chinese medicine composition for treating throat and oral diseases, characterized in that, It is made from the following raw materials: bezoar, gypsum, licorice, borneol, borax, pearl, indigo naturalis, scutellaria baicalensis, andrographis paniculata, phellodendron chinense, alum, talc, dragon's blood, catechu, sodium sulfate, silkworm pupae, fritillaria cirrhosa, peppermint leaves, and chicken gizzard lining.

2. The traditional Chinese medicine composition as described in claim 1, characterized in that, Its preparation method includes the following steps: (I) Ingredients of Combination Drug I: Pearl 1-3 parts, bezoar 1-3 parts, borneol 3-5 parts, alum 8-10 parts, borax 8-10 parts, catechu 4-6 parts, licorice 7-9 parts, talc 40-60 parts. (II) Components of Combination Drug II: 3-5 parts of silkworm, 4-6 parts of fritillaria cirrhosa, 3-5 parts of indigo naturalis, 4-6 parts of phellodendron bark, 4-6 parts of andrographis paniculata, 3-5 parts of peppermint leaf, 4-6 parts of scutellaria baicalensis, 4-6 parts of sodium sulfate, 2-4 parts of dragon's blood, 14-16 parts of gypsum, 11-13 parts of borax, 7-9 parts of licorice, and 2-4 parts of chicken gizzard lining; (III) Specific pharmaceutical manufacturing steps: Step 1: Prepare the combined medicine according to the specified weight proportions. Strictly select various Chinese medicinal materials, clean each material thoroughly, grind them into powder, and dry them. First, mix and dry the catechu and borax. Second, dry the alum separately. Third, mix and dry the licorice and talc. Fourth, grind and dry the bezoar, pearl, and borneol. Fifth, after storing the above four powdered combinations in a dry environment for 2 days, filter them through a 120-mesh sieve, mix them together, and then immediately seal and store them in a container for 3-5 days. Step Two: Prepare the second combination of medicines according to the specified weight proportions. Strictly select various Chinese medicinal materials, clean each material thoroughly, mix and grind them into powder, and immediately seal the mixed powder in a container while the materials are still warm, storing it for 3-5 days. Step 3: Select combination drug 2 at approximately 10% of the proportion of combination drug 1, and mix it evenly with the powder made from combination drug 1 to obtain the Chinese herbal medicine mixed powder. Step 4: After the powder is made, let it air dry for one day, seal it in a bottle or jar, and keep it dry.

3. The traditional Chinese medicine composition as described in claim 2, characterized in that, Its preparation method includes the following steps: (a) Ingredients of Combination Drug 1: 2 parts pearl, 2 parts bezoar, 4 parts borneol, 9 parts alum, 9 parts borax, 5 parts catechu, 8 parts licorice, 50 parts talc. (II) Components of Combination Drug II: 4 parts of silkworm, 5 parts of fritillaria cirrhosa, 4 parts of indigo naturalis, 5 parts of phellodendron bark, 5 parts of andrographis paniculata, 4 parts of peppermint leaf, 5 parts of scutellaria baicalensis, 5 parts of sodium sulfate, 3 parts of dragon's blood, 15 parts of gypsum, 12 parts of borax, 8 parts of licorice, and 3 parts of chicken gizzard lining. (III) Specific pharmaceutical manufacturing steps: Step 1: Prepare the combined medicine according to the specified weight proportions. Strictly select various Chinese medicinal materials, clean each material thoroughly, grind them into powder, and dry them. First, mix and dry the catechu and borax. Second, dry the alum separately. Third, mix and dry the licorice and talc. Fourth, grind and dry the bezoar, pearl, and borneol. Fifth, after storing the above four powdered combinations in a dry environment for 2 days, filter them through a 120-mesh sieve, mix them together, and then immediately seal and store them in a container for 3-5 days. Step Two: Prepare the second combination of medicines according to the specified weight proportions. Strictly select various Chinese medicinal materials, clean each material thoroughly, mix and grind them into powder, and immediately seal the mixed powder in a container while the materials are still warm, storing it for 3-5 days. Step 3: Select combination drug 2 at approximately 10% of the proportion of combination drug 1, and mix it evenly with the powder made from combination drug 1 to obtain the Chinese herbal medicine mixed powder. Step 4: After the powder is made, let it air dry for one day, seal it in a bottle or jar, and keep it dry.

4. The traditional Chinese medicine composition as described in claim 2, characterized in that, The bezoar mentioned is artificial bezoar.

5. The traditional Chinese medicine composition as described in claim 2, characterized in that, The borneol is a natural, first-grade, levorotatory borneol.

6. The traditional Chinese medicine composition according to claim 2, characterized in that, The borax must meet the pharmaceutical standard for Grade I.

7. The use of the pharmaceutical composition of claim 2 in the preparation of treatments and preventions of oral and pharyngeal diseases.

8. The use of the pharmaceutical composition of claim 7 in the preparation of treatments and preventions of oral and pharyngeal diseases, wherein the oral and pharyngeal diseases are oral ulcers, gingival bleeding, sore throat, and tonsillitis.