Hydrogen peroxide low-decomposition constant temperature control system

CN122643482BActive Publication Date: 2026-10-27浙江泰林生命科学有限公司
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Patent Information

Application Number
CN202611116954.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2026-07-27
Publication Date
2026-10-27
Estimated Expiration
2046-07-27

AI Technical Summary

Technical Problem

[0004]目前,应对浓度下降的主要方式是补液汽化,但该方法易引起局部过氧化氢浓度不均,导致灭菌效果不稳定,且未能从根本上解决水分子加速分解的问题

Benefits of technology

1、采用过氧化氢汽化缓冲罐对过氧化氢进行汽化预处理,以提高过氧化氢气体进入灭菌舱时的温度、干燥。

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Abstract

The application provides a hydrogen peroxide low-decomposition constant temperature control system, which comprises a sterilization cabin for storing hydrogen peroxide gas, a buffer tank for conveying hydrogen peroxide gas, a vacuum pump connected with the buffer tank and the sterilization cabin through first and second vacuum pipelines respectively, and a gas pipeline connected between the buffer tank and the sterilization cabin, so that the buffer tank and the sterilization cabin are vacuumized through the first and second vacuum pipelines respectively, and hydrogen peroxide gas in the buffer tank is conveyed into the sterilization cabin through the gas pipeline; and the side of the sterilization cabin is connected to a nitrogen gas heating and drying device through a nitrogen gas pipeline, so that dry nitrogen gas is conveyed into the vacuumized sterilization cabin; the application actively removes water during the hydrogen peroxide sterilization process to inhibit water molecules from accelerating the decomposition of hydrogen peroxide, and can maintain the concentration stable during the hydrogen peroxide sterilization process.
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Description

Technical Field

[0001] This invention relates to the field of hydrogen peroxide sterilization equipment, and in particular to a hydrogen peroxide low-decomposition constant temperature control system. Background Technology

[0002] In industries such as pharmaceutical manufacturing and medical care, hydrogen peroxide sterilization is one of the commonly used sterilization methods. Its sterilization methods are divided into two types: atomization and vaporization. Hydrogen peroxide biological indicators are used to verify the sterilization effect of sterilization equipment, among which the D value is a recognized parameter for measuring the effectiveness of sterilization.

[0003] During low-temperature plasma sterilization with hydrogen peroxide, the liquid hydrogen peroxide solution vaporizes to produce a large amount of water vapor. It is generally believed in the industry that water vapor is merely an inevitable byproduct of the vaporization process and has no substantial impact on the sterilization effect. However, through extensive experimental research, the inventors have discovered that water molecules significantly accelerate the decomposition of hydrogen peroxide, leading to a continuous decrease in the hydrogen peroxide concentration within the sterilization chamber, thereby affecting the stability and reliability of the sterilization effect. In other words, water molecules are not only an inert byproduct but also an active factor accelerating the consumption of the sterilizing agent, and existing technologies have not recognized the need for active water removal during the sterilization process to inhibit decomposition.

[0004] Currently, the main way to deal with the decrease in concentration is to replenish the liquid and vaporize it. However, this method is prone to causing uneven local hydrogen peroxide concentration, resulting in unstable sterilization effect and failing to fundamentally solve the problem of accelerated decomposition of water molecules. Summary of the Invention

[0005] The purpose of this invention is to provide a hydrogen peroxide low-decomposition constant temperature control system that actively removes water during the hydrogen peroxide sterilization process to inhibit the accelerated decomposition of hydrogen peroxide by water molecules, and maintains a stable concentration of hydrogen peroxide during the sterilization process.

[0006] To address the aforementioned technical problems, this invention provides a hydrogen peroxide low-decomposition constant-temperature control system, comprising a sterilization chamber for storing hydrogen peroxide gas and a buffer tank for transporting hydrogen peroxide gas. A vacuum pump is connected to the buffer tank and the sterilization chamber via a first vacuum line and a second vacuum line, respectively. The buffer tank and the sterilization chamber are connected via a gas line, allowing the buffer tank and the sterilization chamber to be evacuated via the first and second vacuum lines, respectively, and the hydrogen peroxide gas in the buffer tank is transported to the sterilization chamber via the gas line. Furthermore, the side of the sterilization chamber is connected to a nitrogen heating and drying device via a nitrogen line, allowing dried nitrogen gas to be transported to the evacuated sterilization chamber.

[0007] Furthermore, a detection chamber is provided in the sterilization chamber by pulling it out. The detection chamber contains a detection indicator, and the movable connection between the detection chamber and the sterilization chamber is sealed. The side of the detection chamber away from the sterilization chamber has a door panel, so that the detection chamber can be used to bring the detection indicator into the sterilization chamber for detection, and the door panel can be opened to observe the detection indicator after the chamber is reset and isolated from the sterilization chamber.

[0008] Furthermore, the buffer tank is connected to the storage bottle via a vaporization chamber, and a pump is connected between the storage bottle and the liquid storage bottle so that the pump can transport the hydrogen peroxide liquid in the storage bottle to the storage bottle, and then transport it to the buffer tank after vaporization via the vaporization chamber.

[0009] Furthermore, the buffer tank is surrounded by a first heating and insulation layer, and the buffer tank contains a first heating component and a first sensor group for detecting temperature, humidity and pressure.

[0010] Furthermore, a filter assembly is provided at the connection between the buffer tank and the first vacuum pipeline to separate water molecules in the hydrogen peroxide gas while retaining hydrogen peroxide molecules. The filter assembly is a 3A-grade molecular sieve membrane.

[0011] Furthermore, the sterilization chamber is surrounded by a second heating and insulation layer, and the sterilization chamber contains a second heating component and a second sensor group for detecting temperature, humidity and hydrogen peroxide concentration.

[0012] Furthermore, the nitrogen heating and drying device has a built-in third heating component and a third sensor group for detecting temperature, humidity and pressure, and the nitrogen heating and drying device has a second adsorption component for adsorbing water molecules. The nitrogen heating and drying device is connected to a nitrogen cylinder for supplying nitrogen on its side.

[0013] Furthermore, the side of the detection chamber is connected to the vacuum pump via a third vacuum line, so that the detection chamber is evacuated by the vacuum pump before it is connected to the sterilization chamber.

[0014] Furthermore, the sterilization chamber is equipped with a first adsorption component for adsorbing water molecules, and the first adsorption component is a 3A molecular sieve.

[0015] Furthermore, the inner walls of both the sterilization chamber and the testing chamber are coated with polytetrafluoroethylene.

[0016] The beneficial effects of this invention are as follows: 1. A hydrogen peroxide vaporization buffer tank is used to pre-treat hydrogen peroxide by vaporization, so as to increase the temperature and dryness of hydrogen peroxide gas when it enters the sterilization chamber.

[0017] 2. Equipped with three-stage dehydration capability: First, at the outlet of the hydrogen peroxide buffer tank, a filtration assembly composed of molecular sieve membranes filters and extracts water molecules, pre-separating water vapor from the mixed gas to reduce the initial moisture entering the sterilization chamber; Second, inside the sterilization chamber, a first adsorption assembly formed by 3A molecular sieve particles continuously adsorbs newly generated moisture and trace amounts of seeping moisture during the sterilization process; Third, during pre-sterilization treatment, dry nitrogen from a nitrogen-heated drying device is used to purge the inside of the sterilization chamber, combined with a second heating assembly and a vacuum pump for heating and vacuuming to reduce moisture adsorbed on the chamber and the surface of the items.

[0018] 3. The filter components of the buffer tank are molecular sieve membranes, and the sterilization chamber and nitrogen heating and drying device are 3A molecular sieves (first adsorption component and second adsorption component) to remove water and reduce hydrogen peroxide decomposition in all aspects of hydrogen peroxide sterilization gas.

[0019] 4. To address the issue of excessively low temperatures during the pretreatment and vacuuming process in the sterilization chamber, this solution employs a multi-stage heating tube system, consisting of a first and second heating insulation layer and a first, second, and third heating assembly, to achieve heating and insulation through thermal radiation. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the structure of the present invention.

[0021] Reference numerals: 1. Sterilization chamber; 11. Second vacuum line; 12. Second heating and insulation layer; 13. Second heating component; 14. Second sensor group; 15. First adsorption component; 2. Buffer tank; 21. First vacuum line; 22. Gas line; 23. Vaporization chamber; 24. Liquid storage bottle; 25. Liquid storage bottle; 26. Pump body; 27. First heating and insulation layer; 28. First heating component; 29. ​​First sensor group; 210. Filter component; 3. Vacuum pump; 4. Nitrogen heating and drying device; 41. Nitrogen line; 42. Third heating component; 43. Third sensor group; 44. Second adsorption component; 45. Nitrogen cylinder; 5. Detection chamber; 51. Detection indicator; 52. Door panel; 53. Third vacuum line. Detailed Implementation

[0022] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention are within the scope of protection of the present invention.

[0023] Those skilled in the art should understand that, in the disclosure of this invention, the terms "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, the above terms should not be construed as limiting this invention.

[0024] It is understood that the term "a" should be understood as "at least one" or "one or more", that is, in one embodiment, the number of an element can be one, while in another embodiment, the number of the element can be multiple, and the term "a" should not be understood as a limitation on the number.

[0025] like Figure 1 As shown, the present invention provides a hydrogen peroxide low-decomposition constant temperature control system, including a sterilization chamber 1 for storing hydrogen peroxide gas, a buffer tank 2 for transporting hydrogen peroxide gas, a vacuum pump 3 connected to the buffer tank 2 and the sterilization chamber 1 via a first vacuum line 21 and a second vacuum line 11 respectively, the buffer tank 2 and the sterilization chamber 1 connected via a gas line 22, so that the buffer tank 2 and the sterilization chamber 1 are evacuated via the first vacuum line 21 and the second vacuum line 11 respectively, and the hydrogen peroxide gas in the buffer tank 2 is transported to the sterilization chamber 1 via the gas line 22; and the side of the sterilization chamber 1 is connected to a nitrogen heating and drying device 4 via a nitrogen line 41, so that dried nitrogen is transported to the sterilization chamber 1 after evacuation.

[0026] The sterilization chamber 1 is equipped with a first adsorption component 15, which can be a high-purity synthetic aluminosilicate (potassium A type) 3A molecular sieve for adsorbing water molecules. The pore size of the 3A molecular sieve is uniform and fixed at 0.3 nm. The dynamic diameter of water molecules is about 0.28 nm, which can smoothly enter the pore structure of the molecular sieve and be adsorbed. However, the dynamic diameter of hydrogen peroxide molecules is about 0.4 nm, which is larger than 0.3 nm, so they cannot enter the pores. Therefore, it selectively absorbs water and does not absorb hydrogen peroxide.

[0027] The sterilization chamber 1 is surrounded by a second heating and insulation layer 12, and the sterilization chamber 1 is equipped with a second heating component 13 and a second sensor group 14 for detecting temperature, humidity and hydrogen peroxide concentration. The second heating component 13 may be a structure of several heating rods, and the second sensor group 14 includes at least a temperature sensor, a humidity sensor and a hydrogen peroxide concentration sensor.

[0028] In one embodiment of this solution, a second vacuum solenoid valve and a third vacuum solenoid valve are respectively installed at the first vacuum line 21 and the second vacuum line 11, a first solenoid valve is installed at the gas line 22, and a second solenoid valve is installed at the nitrogen line 41.

[0029] Meanwhile, the buffer tank 2 is surrounded by a first heating and insulation layer 27, and the buffer tank 2 is equipped with a first heating component 28 and a first sensor group 29 for detecting temperature, humidity and pressure. The first heating component 28 may adopt a structure of several heating rods, and the first sensor group 29 includes at least a temperature sensor, a humidity sensor and a pressure sensor.

[0030] A filter assembly 210 is provided at the connection between the buffer tank 2 and the first vacuum pipeline 21 to separate water molecules in hydrogen peroxide gas while retaining hydrogen peroxide molecules. In one embodiment of this solution, the filter assembly 210 can be a 3A-grade molecular sieve membrane. The buffer tank 2 and the sterilization chamber 1 are evacuated to a lower absolute pressure state by the vacuum pump 3, and then the second vacuum solenoid valve and the third vacuum solenoid valve are closed. At this time, the vaporized hydrogen peroxide water vapor mixture in the buffer tank 2 is mostly removed by the 3A-grade molecular sieve membrane, taking advantage of the principle that hydrogen peroxide molecules are larger in diameter than water molecules. This leaves relatively dry hydrogen peroxide gas.

[0031] In another embodiment of this solution, the nitrogen heating and drying device 4 has a built-in third heating component 42 and a third sensor group 43 for detecting temperature, humidity and pressure, and the nitrogen heating and drying device 4 has a second adsorption component 44 for adsorbing water molecules. The nitrogen heating and drying device 4 is connected to a nitrogen cylinder 45 for supplying nitrogen.

[0032] The third heating component 42 may adopt several heating rod structures, the third sensor group 43 includes at least a temperature sensor, a humidity sensor and a pressure sensor, the second adsorption component 44 may adopt the same high-purity synthetic aluminosilicate (potassium A type) 3A molecular sieve as built into the sterilization chamber 1; at the same time, a third solenoid valve is connected between the nitrogen cylinder 45 and the nitrogen heating and drying device 4.

[0033] Preferably, a detection chamber 5 is retractable in the sterilization chamber 1. The detection chamber 5 contains a detection indicator 51, and the movable connection between the detection chamber 5 and the sterilization chamber 1 is sealed. The side of the detection chamber 5 away from the sterilization chamber 1 has a door panel 52, which allows the detection chamber 5 to pull the detection indicator 51 into the sterilization chamber 1 for detection, and to open the door panel 52 for observation of the detection indicator 51 after resetting and isolating from the sterilization chamber 1. The detection chamber 5 is connected to a drive push rod (not shown in the figure), which can be any of a cylinder, electric cylinder, or manual screw structure, and is used to drive the detection chamber 5 to reciprocate along the pulling direction of the sterilization chamber 1, so as to realize the insertion and resetting of the detection chamber 5 in the sterilization chamber 1.

[0034] Specifically, after the hydrogen peroxide gas in the sterilization chamber 1 reaches the required concentration, the detection chamber 5 is first evacuated. Then, the detection chamber 5 is pushed into the sterilization chamber 1 to test the sterilization effect. After the test is completed, it is pulled out and the detection chamber 5 is isolated from the sterilization chamber 1. At this time, the markings of the detection indicator 51 are observed by opening the door panel 52.

[0035] The inner walls of the sterilization chamber 1 and the testing chamber 5 are coated with polytetrafluoroethylene to slow down the decomposition of hydrogen peroxide.

[0036] In one embodiment of this solution, the side of the detection chamber 5 is connected to the vacuum pump 3 via a third vacuum line 53, so that the detection chamber 5 is first evacuated by the vacuum pump 3 before it is connected to the sterilization chamber 1, and a first vacuum solenoid valve is provided at the third vacuum line 53.

[0037] Preferably, the buffer tank 2 is connected to the storage bottle 24 via the vaporization chamber 23, and a pump body 26 is connected between the storage bottle 24 and the liquid storage bottle 25 so that the pump body 26 can transport the hydrogen peroxide liquid in the storage bottle 25 to the storage bottle 24, and then transport it to the buffer tank 2 after vaporization via the vaporization chamber 23.

[0038] Specifically, the hydrogen peroxide liquid in the storage bottle 25 is transported to the storage bottle 24 by the pump body 26, and then the hydrogen peroxide liquid is vaporized through the vaporization chamber 23 and transported to the buffer tank 2 to ensure a stable supply of hydrogen peroxide to the sterilization chamber 1 by the buffer tank 2.

[0039] The pump body 26 can be a peristaltic pump, the vaporization chamber 23 has several heating rods to ensure the stable vaporization of hydrogen peroxide, and a fourth solenoid valve is connected between the storage bottle 24 and the vaporization chamber 23.

[0040] Based on the above, this solution can be implemented following the procedure below: 1. Preheating stage: The vaporization chamber 23 is heated to 100°C by heating rods, and the sterilization chamber 1 is heated to the required sterilization temperature by heating insulation layer combined with second heating component 13; the buffer tank 2 is heated to the required sterilization temperature by heating insulation layer combined with first heating component 28; the nitrogen heating and drying device 4 is heated to the sterilization temperature by third heating component 42. II. Sterilization Environment Construction Phase: ① Open the second and third vacuum solenoid valves; evacuate the buffer tank 2 and sterilization chamber 1 to a vacuum state, then close the second and third vacuum solenoid valves. The first heating component 28 and the second heating component 13 in the buffer tank 2 and sterilization chamber 1 will heat and assist in heat radiation to preheat the buffer tank 2 and sterilization chamber 1. After preheating for a period of time, open the third solenoid valve, and nitrogen from the nitrogen cylinder 45 will enter the nitrogen heating and drying device 4. After the pressure sensor in the nitrogen heating and drying device 4 reaches the set value, close the third solenoid valve. After a period of preheating, the temperature and humidity sensors in the nitrogen heating and drying device 4 reach the set values, and the second solenoid valve is opened, allowing the nitrogen gas, which is heated during drying, to fill the sterilization chamber 1, and the sterilization chamber 1 returns to normal pressure. During this process, since the buffer tank 2 is still under negative pressure after the aforementioned vacuuming step, the pump body 26 is started in parallel to draw hydrogen peroxide solution from the storage bottle 25 to the storage bottle 24. The fourth solenoid valve is opened, and the liquid in the storage bottle 24 is heated and vaporized through the vaporization chamber 23 under the action of negative pressure and enters the buffer tank 2. ② Open the second and third vacuum solenoid valves; use vacuum pump 3 to evacuate the buffer tank 2 and sterilization chamber 1 to a lower absolute pressure state, and then close the second and third vacuum solenoid valves. At this time, the vaporized hydrogen peroxide water vapor mixture in the buffer tank 2, utilizing the principle that hydrogen peroxide molecules are larger in diameter than water molecules, under the action of the 3A-grade molecular sieve membrane, most of the water vapor is extracted, leaving relatively dry hydrogen peroxide gas; at the same time, the pressure in the buffer tank 2 is greater than the pressure in the sterilization chamber 1. At this time, there is a small amount of dry nitrogen gas in the sterilization chamber 1. Under the action of the second heating component 13 in the sterilization chamber 1, the sterilization chamber 1 can be quickly restored to the sterilization temperature, avoiding the heat taken away during the vacuuming process, which is difficult to restore for a long time, resulting in poor sterilization effect and large and inaccurate D-value test deviation; at the same time, open the first vacuum solenoid valve on the third vacuum pipeline 53 to evacuate the detection chamber 5 to a vacuum state so that sterilization can be carried out after the sterilization concentration reaches the set value.

[0041] ③ The first solenoid valve is opened intermittently. Because the pressure in buffer tank 2 is greater than the pressure in sterilization chamber 1, hydrogen peroxide gas in buffer tank 2 enters sterilization chamber 1 under the action of pressure. After the hydrogen peroxide concentration in sterilization chamber 1 reaches the set value, the first solenoid valve is closed. The drive rod pushes the detection indicator 51 sterilized material into the chamber filled with hydrogen peroxide for sterilization. Since all parts of the mechanical structure that come into contact with hydrogen peroxide gas are coated with polytetrafluoroethylene, the decomposition of hydrogen peroxide can be slowed down. At the same time, the high-purity synthetic aluminosilicate (potassium A type) 3A molecular sieve inside sterilization chamber 1 has a uniform and fixed pore size of 0.3nm, which allows water molecules to move freely. The mechanical diameter is approximately 0.28 nm, allowing it to easily enter the pore structure of the molecular sieve and be adsorbed. However, the kinetic diameter of hydrogen peroxide molecules is approximately 0.4 nm, which is larger than 0.3 nm, preventing them from entering the pores. Therefore, it selectively absorbs only water and not hydrogen peroxide. Furthermore, the high-purity synthetic aluminosilicate (potassium A type) material has high purity and does not contain transition metal impurities such as iron, copper, and manganese. Transition metals are the main catalytic factors for the decomposition of hydrogen peroxide into water and oxygen. The absence of such impurities can inhibit the catalytic decomposition of hydrogen peroxide at its source. It can adsorb water molecules decomposed by hydrogen peroxide during sterilization as well as water molecules introduced by external gases, slowing down the decomposition of hydrogen peroxide and maintaining the sterilization concentration.

[0042] It is worth mentioning that, during the experimental design phase of this scheme, experiments revealed that adding 3A molecular sieve during the sterilization process could increase the concentration maintenance time by more than 20 seconds compared to not adding 3A molecular sieve, and significantly reduce decomposition; as shown in the table below for comparison:

[0043] In the early stages of research and development, this solution evaluated various dehumidification technologies, including: traditional physical desiccants (silica gel), chemical desiccants (calcium chloride), pressure swing distillation (vacuum distillation), selective condensation, and directional dehumidification using electric / acoustic fields. After comprehensive comparison, only 3A molecular sieve could simultaneously meet the following five key requirements: 1. Selectivity Requirements: The dehydration solution must strictly distinguish between water molecules and hydrogen peroxide molecules. Pressure swing distillation and selective condensation cannot avoid hydrogen peroxide loss; non-porous selective desiccants such as silica gel and calcium chloride will simultaneously adsorb hydrogen peroxide, leading to a decrease in sterilization concentration. 3A molecular sieves achieve precise sieving with a precise pore size of 0.3nm, allowing for the absorption of only water and not hydrogen peroxide.

[0044] 2. Thermal Stability and Safety Requirements: The sterilization temperature must fluctuate between 45-55℃, and the equipment must operate stably for extended periods. Silica gel exhibits a significant decrease in adsorption performance at high temperatures; under low humidity conditions at 100℃, 3A molecular sieve absorbs more than 20 times the water of silica gel. Calcium chloride absorbs water, forming a solution and releasing heat, posing a safety hazard. Pressure swing distillation requires heating, and under heating conditions, hydrogen peroxide is highly susceptible to explosive chain decomposition. 3A molecular sieve exhibits excellent thermal stability, withstanding temperatures up to 700℃, and maintains stable performance within the sterilization temperature range.

[0045] 3. Impurity Control Requirements: The dehydration material itself must be free of transition metal impurities (Fe, Cu, Mn), otherwise it will catalyze the decomposition of hydrogen peroxide, causing the "dehydration and catalysis simultaneously" effect to be negated. Industrial-grade desiccants such as silica gel and calcium chloride generally contain trace amounts of transition metal impurities. 3A molecular sieves, as high-purity synthetic materials, allow for strict control of metal impurity content.

[0046] 4. Equipment Integration Requirements: Sterilization equipment needs a compact design, and the dehydration solution must be small in size, simple in structure, and require no significant modifications to the existing equipment architecture. Pressure swing distillation requires a distillation column and a vacuum system, selective condensation requires a condenser trap and a refrigeration module, and electric field / acoustic field solutions require complex transducer arrays, all of which are difficult to integrate. 3A molecular sieves are statically placed in granular or modular form, requiring almost no changes to the equipment structure.

[0047] 5. Operating Cost Requirements: The water removal solution must be characterized by low energy consumption, long lifespan, and maintenance-free operation. Condensation and distillation solutions have extremely high energy consumption; silica gel and calcium chloride require frequent replacement. 3A molecular sieves can be regenerated in situ (moisture can be desorbed and adsorption activity restored by heating to 200-350℃ and introducing dry nitrogen gas), with a cycle life of 7-10 years and the lowest life cycle cost.

[0048] This invention is not limited to the preferred embodiments described above. Anyone can derive other products in various forms under the guidance of this invention. However, regardless of any changes in shape or structure, any technical solution that is the same as or similar to this application falls within the protection scope of this invention.

Claims

1. A constant-temperature control system for low-decomposition hydrogen peroxide, characterized in that: The system includes a sterilization chamber (1) for storing hydrogen peroxide gas and a buffer tank (2) for transporting hydrogen peroxide gas. A vacuum pump (3) is connected to the buffer tank (2) and the sterilization chamber (1) through a first vacuum line (21) and a second vacuum line (11), respectively. The buffer tank (2) and the sterilization chamber (1) are connected through a gas line (22) so that the buffer tank (2) and the sterilization chamber (1) are evacuated through the first vacuum line (21) and the second vacuum line (11), respectively, and the hydrogen peroxide gas in the buffer tank (2) is transported to the sterilization chamber (1) through the gas line (22). The side of the sterilization chamber (1) is connected to a nitrogen heating and drying device (4) through a nitrogen line (41) so that dry nitrogen is transported to the sterilization chamber (1) after evacuation. A filter assembly (210) is provided at the connection between the buffer tank (2) and the first vacuum pipeline (21) to separate water molecules in hydrogen peroxide gas and retain hydrogen peroxide molecules. The filter assembly (210) is a 3A grade molecular sieve membrane. The nitrogen heating and drying device (4) has a third heating component (42) built in, and the nitrogen heating and drying device (4) has a second adsorption component (44) inside, which is used to adsorb water molecules; The sterilization chamber (1) is equipped with a first adsorption component (15) for adsorbing water molecules. The first adsorption component (15) is a 3A molecular sieve.

2. The hydrogen peroxide low-decomposition constant temperature control system according to claim 1, characterized in that: A detection chamber (5) is provided at the sterilization chamber (1) and contains a detection indicator (51). The detection chamber (5) and the sterilization chamber (1) are connected in a sealed manner. The detection chamber (5) has a door panel (52) on the side away from the sterilization chamber (1) so that the detection chamber (5) can be used to bring the detection indicator (51) into the sterilization chamber (1) for detection. After being reset and isolated from the sterilization chamber (1), the door panel (52) can be opened to observe the detection indicator (51).

3. The hydrogen peroxide low-decomposition constant temperature control system according to claim 1, characterized in that: The buffer tank (2) is connected to the storage bottle (24) via a vaporization chamber (23). A pump body (26) is connected between the storage bottle (24) and the storage bottle (25) so that the pump body (26) can transport the hydrogen peroxide liquid in the storage bottle (25) to the storage bottle (24), and then transport it to the buffer tank (2) after vaporization via the vaporization chamber (23).

4. The hydrogen peroxide low-decomposition constant temperature control system according to claim 1, characterized in that: The buffer tank (2) is surrounded by a first heating and insulation layer (27), and the buffer tank (2) is equipped with a first heating component (28) and a first sensor group (29) for detecting temperature, humidity and pressure.

5. The hydrogen peroxide low-decomposition constant temperature control system according to claim 1, characterized in that: The sterilization chamber (1) is surrounded by a second heating and insulation layer (12), and the sterilization chamber (1) is equipped with a second heating component (13) and a second sensor group (14) for detecting temperature, humidity and hydrogen peroxide concentration.

6. The hydrogen peroxide low-decomposition constant temperature control system according to claim 1, characterized in that: The nitrogen heating and drying device (4) has a built-in third sensor group (43) for detecting temperature, humidity and pressure, and a nitrogen cylinder (45) for supplying nitrogen is connected to the side of the nitrogen heating and drying device (4).

7. The hydrogen peroxide low-decomposition constant temperature control system according to claim 2, characterized in that: The side of the detection chamber (5) is connected to the vacuum pump (3) through a third vacuum pipeline (53) so that the detection chamber (5) is first vacuumed by the vacuum pump (3) before it is connected to the sterilization chamber (1).

8. The hydrogen peroxide low-decomposition constant temperature control system according to claim 2, characterized in that: The inner walls of both the sterilization chamber (1) and the testing chamber (5) are coated with polytetrafluoroethylene.

Citation Information

Patent Citations

  • Improved aerosol

    CN101237895A

  • Hydrogen peroxide low-temperature sterilizer, sterilization method and purification device

    CN113134104A

  • Gas sterilization resistance detection device for zero rising period of gas concentration and detection method thereof

    CN116899003A

  • Ethylene oxide sterilization resistance instrument and use method thereof

    CN122430519A