A device for preparing high-purity water for injection by a whole membrane method

Abstract

The embodiment of the application provides a kind of whole membrane method high-purity injection water preparation device, it is related to water filtration technical field.The whole membrane method high-purity injection water preparation device includes outer tube, filter module, locking module and installation module.Installation module contains installation cover and the partition plate in its inside, partition plate separates installation cover into outer groove and inner groove, and is slidably connected with locking module.Locking module contains installation block slidably connected with inner and outer groove, and the inner side of installation block is equipped with clamping groove.Trapezoidal block of locking assembly is clamped with clamping groove, and the lateral locking of clamping block is pushed by clamping pin, to form double anti-loose structure.The membrane bundle barrel of filter module is fixed with locking module by installation ring.The device is effectively resistant to water pressure impact, vibration and thermal stress by multiple locking and dynamic pre-tightening, prevent connection loosening and axial movement, eliminate raw water short-circuit phenomenon, ensure that the index of injection water meets the requirements.

Description

Technical Field

[0001] This invention relates to the field of water filtration technology, and in particular to a membrane-based apparatus for preparing high-purity water for injection. Background Technology

[0002] Water for injection is a critical process water in pharmaceuticals, bioengineering, and high-end medical devices, requiring extremely stringent purity standards, including conductivity, total organic carbon, and microbial limits. All-membrane water treatment technology, with its advantages of room-temperature operation, no phase change, no chemical additives, and stable effluent quality, has gradually become the mainstream process for producing high-purity water for injection. A typical all-membrane system usually integrates membrane modules such as ultrafiltration, reverse osmosis, electro-deionization, and terminal ultrafiltration, requiring numerous interconnections between membrane units and between the membrane units and external piping and housing.

[0003] In existing preparation devices, filtration modules (such as membrane bundles) are typically fixed to the outer cylinder via end caps, flanges, threaded sleeves, and other components, and sealed with sealing rings. However, in actual operation, it has been found that traditional connectors are prone to loosening or axial movement due to the long-term stress caused by circulating water pressure, equipment vibration, and alternating hot and cold temperatures, leading to seal failure. In particular, when the fastening force at the connection weakens, raw water may bypass the membrane bundle and directly enter the product water side, causing a "short circuit" phenomenon, which seriously affects the conductivity and microbial control indicators of the water for injection.

[0004] Therefore, how to achieve a fast, stable, and non-loosening connection between the filter module and the housing and external connectors while ensuring high sealing performance has become a key technical problem to be solved in this field. Summary of the Invention

[0005] This application provides a membrane-based high-purity water for injection preparation apparatus, comprising an outer cylinder, a filter module inside the outer cylinder, a locking module connected to the outer cylinder and the filter module, and an installation module for connecting to an external connector. The installation module includes an installation cover, and a partition plate is fixedly provided on the inner side of the installation cover. The partition plate divides the inner side of the installation cover into an outer groove and an inner groove, and both the outer groove and the inner groove are slidably connected to the locking module. The installation module also includes a locking assembly, which cooperates with the locking module to connect the installation module and the locking module. A hollow groove is provided on the inner side of the partition plate, and a fixing sleeve is fixedly provided on the inner side of the hollow groove. A snap-fit ​​pin is provided on one side of the fixing sleeve, and the snap-fit ​​pin cooperates with the locking module to connect the locking module and the installation cover.

[0006] Preferably, the locking module includes a mounting block that is slidably connected to the inner groove or the outer groove, and the inner side of the mounting block is provided with a locking groove corresponding to the locking component. The mounting block that is slidably connected to the inner groove or the outer groove and the locking groove on its inner side enable the locking module and the mounting cover to be quickly positioned and pre-fixed, thereby improving assembly efficiency.

[0007] Preferably, the locking assembly includes a fixing ring, and a fixing rod is fixedly provided on one side of the fixing ring. A snap-fit ​​assembly is fixedly provided at the end of the fixing rod away from the fixing ring. The snap-fit ​​assembly cooperates with the snap-fit ​​groove to connect the installation module and the locking module. By utilizing the cooperation of the fixing ring, the fixing rod, the snap-fit ​​assembly and the snap-fit ​​groove, the locking connection between the installation module and the locking module is realized, which facilitates maintenance and replacement.

[0008] Preferably, a sliding rod is fixedly installed in the locking groove, and a slider is slidably installed on the outside of the sliding rod. A locking block is fixedly installed on one side of the slider, and the locking block cooperates with the locking pin to lock the partition plate and the mounting block. The sliding rod, slider and locking block are installed in the locking groove. Through the cooperation of the locking block and the locking pin, the partition plate and the mounting block are further locked, which enhances the anti-loosening ability.

[0009] Preferably, the snap-fit ​​assembly includes a fixing block fixedly connected to the fixing rod, and a spring plate arranged in a circumferential array is fixedly provided on one side of the fixing block. A trapezoidal block is fixedly provided at the end of the spring plate away from the fixing block, and the trapezoidal block is adapted to the snap-fit ​​groove and the slider. The snap-fit ​​assembly adopts a spring plate and trapezoidal block structure. The trapezoidal block is adapted to the snap-fit ​​groove and the slider to realize automatic snap-fit ​​when inserted, which simplifies the installation operation.

[0010] Preferably, a spring is fixedly provided on one side of the fixing block, and the end of the spring away from the fixing block is fixedly connected to the mounting cover. The spring is provided on the outside of the fixing rod, which provides a continuous axial preload.

[0011] Preferably, the filtration module includes a membrane bundle, and both ends of the membrane bundle are fixedly provided with mounting rings that are fixedly connected to the locking module. The filtration module adopts a structure in which mounting rings are fixed at both ends of the membrane bundle, and the mounting rings are fixedly connected to the locking module, which ensures the overall stability and centering of the membrane bundle.

[0012] Preferably, an annular positioning groove is provided on the inner side of the mounting ring, and the end of the membrane bundle tube is embedded in the annular positioning groove and fixed and sealed with sealant. The annular positioning groove is provided on the inner side of the mounting ring, and the end of the membrane bundle tube is embedded in and fixed and sealed with sealant, which effectively prevents the raw water from leaking from the end bypass and avoids the "short circuit" phenomenon.

[0013] Preferably, an upper mounting sleeve is fixedly connected to the outside of the mounting module, and the top surface of the upper mounting sleeve is connected to a purified water outlet. One side of the upper mounting sleeve is connected to a wastewater outlet, which is used to discharge unpurified sewage. By setting the upper mounting sleeve and the purified water outlet on its top surface and the wastewater outlet on its side, the production water and wastewater are separated and discharged, which facilitates system integration.

[0014] Preferably, a lower mounting sleeve is fixedly connected to the outer end of the mounting module away from the upper mounting sleeve, and a raw water inlet is connected to the outer side of the lower mounting sleeve. The raw water inlet is set on the outer side of the lower mounting sleeve, forming an inlet and outlet structure with the upper mounting sleeve, which is conducive to the uniform distribution of raw water and reduces flow resistance.

[0015] This invention provides a membrane-based high-purity water-for-injection preparation apparatus, which, compared with existing technologies, offers the following advantages: This all-membrane high-purity water for injection preparation device achieves rapid alignment and precise assembly between the filter module and the mounting cover by setting an outer and inner groove formed by a partition plate, in conjunction with the sliding guide of the mounting block of the locking module. At the same time, the trapezoidal block in the locking assembly forms an elastic engagement with the locking groove, and the locking pin pushes the slider and the locking block to lock laterally, forming a double mechanical anti-loosening structure. The spring provides a continuous axial preload, which effectively compensates for the thermal stress caused by water pressure impact, equipment vibration and alternating hot and cold temperatures during long-term operation. It eliminates the problems of easy loosening and axial movement of traditional connectors, and improves the stability of the connection and the durability of the seal.

[0016] This all-membrane high-purity water for injection preparation device ensures a tight seal at both ends of the membrane bundle during operation, completely preventing raw water from bypassing the filtration module and directly entering the product water side, thus eliminating the "short circuit" phenomenon. Combined with the annular positioning groove and sealant within the mounting ring, the end-face seal is further strengthened, ensuring that the product water quality consistently meets the stringent requirements for conductivity, total organic carbon, and microbial limits for water for injection. Furthermore, the device employs a bottom-in, top-out flow path layout and a one-time installation design, reducing daily maintenance needs and providing a highly reliable, low-risk all-membrane water production solution for the pharmaceutical and bioengineering fields. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of the present invention and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained from these drawings without creative effort.

[0018] Figure 1 This is a three-dimensional structural diagram of the filter component of the device of the present invention; Figure 2 This is a three-dimensional disassembled structural diagram of the filter component of the device of the present invention; Figure 3 This is a three-dimensional structural diagram of the installation module of the present invention; Figure 4 This is a three-dimensional sectional view of the installation module of the present invention; Figure 5 This is a schematic diagram of the connection structure between the installation module and the locking module of the present invention; Figure 6 For the present invention Figure 5 Enlarged structural diagram at point A; Figure 7 This is a three-dimensional structural diagram of the locking component of the present invention; Figure 8 This is a three-dimensional structural diagram of the snap-fit ​​component of the present invention; Figure 9 This is a three-dimensional structural diagram of the filtering module of the present invention; Figure 10 This is a schematic diagram of the overall three-dimensional structure of the device of the present invention.

[0019] icon: 1. Outer cylinder; 2. Mounting module; 3. Filtering module; 4. Locking module; 11. Lower mounting sleeve; 12. Raw water inlet; 13. Upper mounting sleeve; 14. Wastewater outlet; 15. Purified water outlet; 21. Mounting cover; 22. Divider plate; 23. Outer groove; 24. Inner groove; 25. Locking assembly; 31. Membrane bundle tube; 32. Mounting ring; 41. Mounting block; 42. Engaging groove; 43. Sliding rod; 44. Sliding block; 45. Engaging block; 221. Hollow groove; 222. Fixing sleeve; 223. Snap-fit ​​pin; 251. Fixing ring; 252. Fixing rod; 253. Snap-fit ​​assembly; 254. Spring; 2531. Fixing block; 2532. Spring plate; 2533. Trapezoidal block. Detailed Implementation

[0020] The following detailed description of some embodiments of the present invention is provided in conjunction with the accompanying drawings. Unless otherwise specified, the following embodiments and features can be combined with each other.

[0021] Please refer to Figures 1-10 This invention provides a membrane-based high-purity water for injection preparation device, comprising an outer cylinder 1, a filter module 3 disposed inside the outer cylinder 1, a locking module 4 connected to the outer cylinder 1 and the filter module 3, and an installation module 2 for connecting to external connecting parts such as pipelines. The installation module 2 is fixedly disposed at both ends of the outer cylinder 1, and cooperates with the upper installation sleeve 13 and the lower installation sleeve 11 respectively to realize functional zoning for water inlet and outlet.

[0022] The mounting module 2 includes a mounting cover 21, on the inner side of which an annular partition plate 22 is fixedly disposed. This partition plate 22 divides the inner space of the mounting cover 21 into an outer groove 23 and an inner groove 24. Both the outer groove 23 and the inner groove 24 are slidably connected to the locking module 4, guiding and accommodating the end of the locking module 4. This configuration, through the double-groove guide structure, enables rapid alignment between the locking module 4 and the mounting cover 21, avoiding sealing failure caused by eccentric installation.

[0023] The mounting module 2 also includes a locking assembly 25, which cooperates with the locking module 4 to fix the mounting module 2 and the locking module 4 together. A hollow groove 221 is provided inside the partition plate 22, and a fixing sleeve 222 is fixedly installed on the inner side of the hollow groove 221. A snap-fit ​​pin 223 is provided on one side of the fixing sleeve 222, which cooperates with the locking module 4 to further lock the locking module 4 and the mounting cover 21. By setting up a double locking structure of the locking assembly 25 and the snap-fit ​​pin 223, the system can effectively resist water pressure impact and vibration during long-term operation, prevent axial movement, and thus eliminate the phenomenon of raw water "short circuit".

[0024] The locking module 4 includes multiple mounting blocks 41, which are slidably connected to the inner groove 24 or the outer groove 23, respectively. Each mounting block 41 has an engagement groove 42 on its inner side, and the position of the engagement groove 42 corresponds to the locking assembly 25. Specifically, when the mounting block 41 slides into place along the groove, the end of the locking assembly 25 can enter the engagement groove 42 and form a locking engagement.

[0025] The locking assembly 25 includes a retaining ring 251, which is fixedly installed on the outer or inner wall of the mounting cover 21. A retaining rod 252 is fixedly provided on one side of the retaining ring 251, and a snap-fit ​​assembly 253 is fixedly provided at the end of the retaining rod 252 away from the retaining ring 251. The snap-fit ​​assembly 253 cooperates with the snap-fit ​​groove 42 to achieve a locking connection between the mounting module 2 and the locking module 4. Its beneficial effect is that, through the linkage of the retaining rod 252 and the snap-fit ​​assembly 253, the locking force can be evenly transmitted to multiple mounting blocks 41, preventing uneven local force distribution.

[0026] A sliding rod 43 is fixedly installed inside the locking groove 42, and a slider 44 is slidably installed on the outer side of the sliding rod 43. A locking block 45 is fixedly installed on one side of the slider 44. The locking block 45 cooperates with the locking pin 223 to lock the partition plate 22 and the mounting block 41. During actual installation, when the mounting block 41 is inserted into the inner groove 24 or the outer groove 23 to the predetermined position, the locking pin 223 on the partition plate 22 will insert into the locking groove 42 and push the slider 44 to move along the sliding rod 43, thereby causing the locking block 45 to extend outward and lock the side wall of the mounting block 41 or the inner wall of the partition plate 22, forming a mechanical anti-detachment structure. It can maintain a locked state under water pressure fluctuations and alternating thermal stress, greatly improving the long-term reliability of the connection.

[0027] The snap-fit ​​assembly 253 includes a fixing block 2531 fixedly connected to the fixing rod 252. Multiple spring plates 2532 arranged in a circumferential array are fixedly disposed on one side of the fixing block 2531. A trapezoidal block 2533 is fixedly disposed at the end of the spring plate 2532 away from the fixing block 2531. This trapezoidal block 2533 is adapted to both the snap-fit ​​groove 42 and the slider 44. During installation, the trapezoidal block 2533 enters the snap-fit ​​groove 42 along with the fixing rod 252, first contacting and sliding the slider 44. Subsequently, the spring plate 2532 elastically deforms, causing the trapezoidal block 2533 to pass over the slider 44 and finally snap onto the stepped surface of the snap-fit ​​groove 42, producing a "click" sound to indicate that the locking is complete. This structure achieves quick assembly with insertion and locking, requiring no additional tools and suitable for on-site installation.

[0028] A spring 254 is also fixedly installed on one side of the fixing block 2531. The end of the spring 254 away from the fixing block 2531 is fixedly connected to the mounting cover 21, and the spring 254 is sleeved on the outside of the fixing rod 252. After the snap-fit ​​assembly 253 is fully snapped into the snap-fit ​​groove 42, the spring 254 is in a stretched state, continuously applying a pulling force towards the mounting cover 21 to the fixing block 2531. This pulling force is converted into an axial preload force on the entire locking module 4 through the fixing rod 252 and the fixing ring 251, so that the filter module 3 is always tightly attached to the end face sealing structure, avoiding separation of the sealing surface due to thermal expansion and contraction or vibration.

[0029] The filter module 3 includes a membrane bundle 31, with mounting rings 32 fixedly installed at both ends of the membrane bundle 31. The mounting rings 32 are fixedly connected to the locking module 4. Specifically, the mounting rings 32 can be welded or bolted to the mounting block 41 of the locking module 4. In this way, the locking force on the locking module 4 can be evenly transmitted to both ends of the membrane bundle 31, preventing the membrane bundle 31 from moving inside the outer cylinder 1.

[0030] Furthermore, an annular positioning groove is provided on the inner side of the mounting ring 32, and the end of the membrane bundle 31 is embedded in the annular positioning groove and fixed and sealed with sealant. This structure not only provides radial positioning for the membrane bundle 31, but also completely seals the end face with sealant, completely preventing raw water from bypassing into the product water side from the gap between the outside of the membrane bundle 31 and the mounting ring 32, thereby improving the quality of the product water.

[0031] To ensure the overall operation of the device, an upper mounting sleeve 13 is fixedly connected to the outer side of the mounting module 2. The top surface of the upper mounting sleeve 13 is connected to a purified water outlet 15 for discharging purified high-purity injection water. Simultaneously, a wastewater outlet 14 is connected to one side of the upper mounting sleeve 13 for discharging concentrated wastewater or rinsing water that has not passed through the membrane bundle 31. A lower mounting sleeve 11 is fixedly connected to the outer side of the mounting module 2, away from the upper mounting sleeve 13. The outer side of the lower mounting sleeve 11 is connected to a raw water inlet 12. This forms a bottom-in, top-out flow path: raw water enters the outer cylinder 1 from the lower mounting sleeve 11, is filtered and separated by the membrane bundle 31, purified water is drawn out from the purified water outlet 15 at the center or top, and wastewater is discharged from the wastewater outlet 14 on the side. This layout facilitates bubble removal and reduces the stagnation zone, improving filtration efficiency.

[0032] When using this all-membrane high-purity water for injection preparation device, first, fix both ends of the membrane bundle 31 to the annular positioning groove of the mounting ring 32 with sealant, and fix it to the mounting block 41 of the locking module 4; then, slide the lower mounting block 41 into the outer groove 23 and inner groove 24 formed by the partition plate 22 of the mounting cover 21 respectively, push it upward until the engaging groove 42 contacts the trapezoidal block 2533 of the locking assembly 25, continue pushing in to make the spring plate 2532 retract and reset, and the trapezoidal block 2533 engage with the engaging groove 42, at the same time The snap-fit ​​pin 223 on the partition plate 22 is inserted into the snap-fit ​​groove 42, and the slider 44 causes the snap-fit ​​block 45 to extend laterally to lock the mounting block 41. The spring 254 is stretched to provide axial preload, completing the lower end fixation. The upper end is locked to the upper mounting cover 21 in the same way. Finally, the upper mounting sleeve 13 and the lower mounting sleeve 11 are fixed to the outside of the corresponding mounting module 2 respectively, and connected to the raw water inlet 12, the purified water outlet 15 and the wastewater outlet 14. The installation is completed in one go without disassembly.

[0033] During operation, raw water enters the annular space between the outer cylinder 1 and the membrane bundle 31 through the raw water inlet 12 of the lower mounting sleeve 11. Driven by water pressure, it passes through the membrane wall of the membrane bundle 31 and enters the interior, resulting in high-purity water for injection. The purified water flows upward sequentially through the upper mounting ring 32, the gap of the mounting block 41 of the locking module 4, and the inner cavity of the mounting module 2, and finally exits from the purified water outlet 15 at the top of the upper mounting sleeve 13. The concentrated water that fails to pass through is discharged from the wastewater outlet 14 on the side of the upper mounting sleeve 13. During this process, the mechanical engagement of the trapezoidal block 2533 and the locking groove 42, and the lateral locking of the sliding block 44 and the locking block 45 by the locking pin 223 form a double anti-loosening mechanism. The spring 254 continuously applies axial tension to dynamically compensate for the small displacements caused by thermal stress and vibration, ensuring that the sealing surfaces at both ends of the membrane bundle 31 are always tightly fitted, preventing raw water from bypassing the membrane bundle 31 and directly entering the product water side, thereby maintaining the conductivity and microbiological indicators of the water for injection in a long-term stable manner.

[0034] The above are merely preferred embodiments of the present invention and are not intended to limit the present invention. For those skilled in the art, the present invention can have various modifications and variations. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the scope of protection of the present invention.

Claims

1. A membrane-based high-purity water for injection preparation apparatus, characterized in that: The device includes an outer cylinder (1), a filter module (3) inside the outer cylinder (1), a locking module (4) connected to the outer cylinder (1) and the filter module (3), and an installation module (2) for connecting to an external connector. The installation module (2) includes a mounting cover (21), and a partition plate (22) is fixedly provided on the inner side of the mounting cover (21). The partition plate (22) divides the inner side of the mounting cover (21) into an outer groove (23) and an inner groove (24), and both the outer groove (23) and the inner groove (24) are slidably connected to the locking module (4). The installation module (2) further includes a locking component (25), and the locking component (25) cooperates with the locking module (4) to connect the installation module (2) and the locking module (4). The inner side of the partition plate (22) is provided with a hollow groove (221), and a fixing sleeve (222) is fixedly provided on the inner side of the hollow groove (221). A snap-fit ​​pin (223) is provided on one side of the fixing sleeve (222), and the snap-fit ​​pin (223) cooperates with the locking module (4) to connect the locking module (4) and the installation cover (21).

2. The apparatus for preparing high-purity water for injection using a full-membrane method according to claim 1, characterized in that: The locking module (4) includes a mounting block (41) that is slidably connected to the inner groove (24) or the outer groove (23), and the inner side of the mounting block (41) is provided with a locking groove (42) corresponding to the locking component (25).

3. The apparatus for preparing high-purity water for injection using a full-membrane method according to claim 2, characterized in that: The locking assembly (25) includes a retaining ring (251), and a retaining rod (252) is fixedly provided on one side of the retaining ring (251). A snap-fit ​​assembly (253) is fixedly provided at the end of the retaining rod (252) away from the retaining ring (251), and the snap-fit ​​assembly (253) cooperates with the snap-fit ​​groove (42) to connect the installation module (2) and the locking module (4).

4. The apparatus for preparing high-purity water for injection using a full-membrane method according to claim 2, characterized in that: A slide rod (43) is fixedly installed in the locking groove (42), and a slider (44) is slidably installed on the outside of the slide rod (43). A locking block (45) is fixedly installed on one side of the slider (44), and the locking block (45) cooperates with the locking pin (223) to lock the partition plate (22) and the mounting block (41).

5. The apparatus for preparing high-purity water for injection using a full-membrane method according to claim 3, characterized in that: The snap-fit ​​assembly (253) includes a fixing block (2531) fixedly connected to the fixing rod (252), and a spring plate (2532) arranged in a circumferential array is fixedly provided on one side of the fixing block (2531). A trapezoidal block (2533) is fixedly provided at the end of the spring plate (2532) away from the fixing block (2531), and the trapezoidal block (2533) is adapted to both the snap-fit ​​groove (42) and the slider (44).

6. The apparatus for preparing high-purity water for injection using a full-membrane method according to claim 5, characterized in that: A spring (254) is fixedly installed on one side of the fixing block (2531), and the end of the spring (254) away from the fixing block (2531) is fixedly connected to the mounting cover (21). The spring (254) is located on the outside of the fixing rod (252).

7. The apparatus for preparing high-purity water for injection using a full-membrane method according to claim 1, characterized in that: The filter module (3) includes a membrane bundle (31), and both ends of the membrane bundle (31) are fixedly provided with mounting rings (32) that are fixedly connected to the locking module (4).

8. The apparatus for preparing high-purity water for injection using a full-membrane method according to claim 7, characterized in that: The inner side of the mounting ring (32) is provided with an annular positioning groove, and the end of the membrane bundle tube (31) is embedded in the annular positioning groove and fixed and sealed with sealant.

9. The apparatus for preparing high-purity water for injection using a full-membrane method according to claim 1, characterized in that: The installation module (2) is fixedly connected to an upper mounting sleeve (13), and the top surface of the upper mounting sleeve (13) is connected to a purified water outlet (15). One side of the upper mounting sleeve (13) is connected to a wastewater outlet (14), and the wastewater outlet (14) is used to discharge unpurified sewage.

10. The apparatus for preparing high-purity water for injection using a full-membrane method according to claim 9, characterized in that: The lower mounting sleeve (11) is fixedly connected to the outer end of the mounting module (2) away from the upper mounting sleeve (13), and the outer side of the lower mounting sleeve (11) is connected to the raw water inlet (12).

Images