A magnetic suction device, microneedle mold core manufacturing equipment and a method of using the same

Abstract

This invention relates to the technical field of microneedle rearrangement, and more particularly to a magnetic adsorption device, a microneedle mold core manufacturing equipment, and a method of using the same. The device includes multiple magnetic adsorption devices, a support, a connecting seat, a drive assembly, at least two telescopic components, a rotating seat, a mold core seat with adhesive curing agent, a moving stage, and a transfer box with ferromagnetic microneedles. Its advantages include: through the rotational coordination of the connecting seat, rotating seat, drive assembly, and multiple magnetic adsorption devices, rapid switching of the magnetic adsorption devices between the transfer box and the mold core seat is achieved; the telescopic components correspond one-to-one with the magnetic adsorption devices in the vertical direction, ensuring accurate transmission of the downward pressure force and avoiding offset or empty pressure; the mold core seat and transfer box are both located below the rotating seat and vertically corresponding to the magnetic adsorption devices, and the moving stage drives the mold core seat to move, allowing multiple microneedle bonding positions to be sequentially aligned with the adsorption devices, achieving array-style parallel operation.

Description

Technical Field

[0001] This invention relates to the technical field of microneedle rearrangement, and more particularly to a magnetic suction device, microneedle core manufacturing equipment, and a method of using the same. Background Technology

[0002] A microneedle array is a miniaturized device consisting of numerous micrometer-sized needle-like structures arranged in a specific pattern on a substrate. High aspect ratio microneedles refer to slender structures with a high height-to-bottom diameter ratio. The microneedle mold core is the core mold component used for mass production of microneedle array products via thermoforming or injection molding. Its precision and consistency directly determine the final product's molding quality. In practical applications, uneven microneedle array arrangement, inconsistent heights, or excessive vertical deviations will lead to uneven drug delivery or signal acquisition failure. Therefore, the height, spacing, taper, and verticality of each microneedle in the array must be highly uniform to ensure the reliability and repeatability of the device performance.

[0003] Currently, the mass production of high aspect ratio microporous array products heavily relies on hot stamping or injection molding of high aspect ratio microstructure array mold cores. However, mold core processing faces numerous technical bottlenecks. First, traditional machining methods have limited precision, making it difficult to form microstructures with large aspect ratios at the micrometer level, easily leading to problems such as dimensional deviations, structural deformation, and uneven array arrangement. Second, traditional microneedle mold core implantation relies heavily on manual operation, which is cumbersome, inefficient, and costly, making it difficult to achieve large-scale production. Furthermore, large positioning errors by humans can easily cause defects such as insufficient microneedle perpendicularity, uneven implantation depth and spacing, resulting in low mold core precision and yield. Third, existing automated equipment is bulky, has high investment and maintenance costs, and its processes are rigid and poorly adaptable, making it impossible to quickly adjust processing parameters according to different mold core specifications, thus failing to meet the demands of flexible production across multiple product categories and at high speeds.

[0004] Therefore, there is an urgent need for a magnetic suction device, microneedle core manufacturing equipment, and its usage method, which can efficiently produce microneedle array cores. Summary of the Invention

[0005] (a) Technical problems to be solved

[0006] In view of the above-mentioned shortcomings and deficiencies of the prior art, the present invention provides a magnetic suction device, a microneedle mold core manufacturing equipment and a method for using the same, which solves the technical problem of low efficiency in manufacturing microneedle array mold cores in the prior art.

[0007] (II) Technical Solution

[0008] To achieve the above objectives, the main technical solutions adopted by the present invention include:

[0009] In a first aspect, embodiments of the present invention provide a magnetic aspiration device, comprising a push rod cylinder, a fixed cylinder, a magnetic microneedle push rod, a spring, and a push rod fixing plate; the push rod cylinder is fixed above the fixed cylinder, and a microneedle through hole extending vertically through the fixed cylinder is opened at the center of the fixed cylinder, the microneedle through hole being coaxial with the magnetic microneedle push rod, the top end of the magnetic microneedle push rod being fixed to the push rod fixing plate, and the bottom end of the magnetic microneedle push rod passing through the bottom of the push rod cylinder and extending into the microneedle through hole; the push rod fixing plate is slidably connected inside the push rod cylinder, and the spring is sleeved outside the magnetic microneedle push rod, with both ends of the spring elastically abutting against the push rod fixing plate and the bottom end of the push rod cylinder, respectively, so that when the push rod fixing plate is pressed down, the push rod fixing plate drives the magnetic microneedle push rod to move downward until the ferromagnetic microneedle is attracted to the bottom end of the magnetic microneedle push rod; when the pressure is released, the restoring force of the spring drives the push rod fixing plate to slide upward, thereby driving the ferromagnetic microneedle into the microneedle through hole.

[0010] Optionally, the magnetic attraction device also includes a ring magnet; the inside of the fixed cylinder is provided with a protrusion extending in a vertical direction, the microneedle perforation passes through the protrusion, the ring magnet is set in the annular space formed by the protrusion and the inner wall of the fixed cylinder, and the bottom end of the magnetic microneedle push rod is located below the ring magnet, so that the magnetic microneedle push rod is magnetized by the ring magnet.

[0011] Optionally, the bottom of the microneedle perforation is chamfered, and the chamfer angle is 30°-60°.

[0012] Secondly, embodiments of the present invention provide a microneedle mold core manufacturing device, including multiple magnetic suction devices, a support, a connecting seat, a driving assembly, at least two telescopic assemblies, a rotating seat, a mold core seat with an adhesive curing agent, a moving stage, and a transfer box with ferromagnetic microneedles; the connecting seat is fixedly connected to the support, the rotating seat is rotatably connected to the bottom of the connecting seat, the driving assembly is connected to the connecting seat and is drivingly connected to the rotating seat, at least two telescopic assemblies are fixed to the periphery of the connecting seat, multiple magnetic suction devices are fixed to the periphery of the rotating seat, the telescopic assemblies and magnetic suction devices correspond vertically, the mold core seat is connected above the moving stage, and the mold core... Both the core holder and the transfer box are located below the rotating base, allowing each core holder and transfer box to correspond vertically with different magnetic absorbing devices. The rotating base is driven to rotate by the drive assembly, which in turn drives the magnetic absorbing devices to rotate, enabling the magnetic absorbing devices to correspond with the core holder and the transfer box. The magnetic absorbing devices are extended and retracted by the telescopic assembly, causing them to attract ferromagnetic microneedles when they correspond with the transfer box. When the magnetic absorbing devices correspond with the core holder, the moving stage moves the core holder, and the magnetic absorbing devices insert and adhere the ferromagnetic microneedles to multiple microneedle bonding positions on the core holder, thus forming a microneedle array within the core holder.

[0013] Optionally, the telescopic assembly includes a drive cylinder and a cylinder push rod; the drive cylinder is fixed to the periphery of the connecting seat, and the cylinder push rod is driven to connect with the drive cylinder, so that one end of the cylinder push rod extends out of the drive cylinder and selectively squeezes the magnetic suction device, and when the telescopic assembly corresponds to the magnetic suction device, the cylinder push rod and the magnetic microneedle push rod are coaxial.

[0014] Optionally, the drive assembly includes a first driver, an internal gear, and an external gear; the first driver is fixed inside the connecting seat, and the drive end of the first driver is fixedly connected to the internal gear, the internal gear meshes with the external gear, the external gear is fixed to the top of the rotating seat, and the internal gear is driven to rotate by the first driver, thereby driving the rotating seat to rotate.

[0015] Optionally, the rotating seat includes a bearing component and a seat body. The bearing component is sleeved on the bottom end of the connecting seat, the seat body is sleeved on the outside of the bearing component, and several magnetic attraction devices are fixed on the periphery of the seat body.

[0016] Optionally, the moving stage includes a first moving block, a second moving block, an X-axis threaded rod, a Y-axis threaded rod, a second driver, a third driver, a first sliding seat, and a second sliding seat. The first moving block is slidably connected to the first sliding seat. The second driver is fixed to one end of the first sliding seat and is driven by the X-axis threaded rod. The X-axis threaded rod is threadedly connected to the first moving block, and the top end of the first moving block is fixedly connected to the second sliding seat. The second moving block is slidably connected to the second sliding seat. The third driver is fixed to one end of the second sliding seat and is driven by the Y-axis threaded rod. The Y-axis threaded rod is threadedly connected to the second moving block, and the mold core seat is fixed to the top end of the second moving block. The horizontal projection of the X-axis threaded rod intersects the horizontal projection of the Y-axis threaded rod. Driven by the second and third drivers, the mold core seat moves at equal intervals along the horizontal direction, forming multiple microneedle bonding positions in the mold core seat. Ferromagnetic microneedles inserted into the microneedle bonding positions by the magnetic suction device form an array.

[0017] Thirdly, embodiments of the present invention provide a method for using a microneedle core manufacturing equipment, comprising the following steps:

[0018] S1. Place the transfer box and the mold core holder on the periphery of the rotating seat respectively;

[0019] S2. The drive assembly drives the rotating seat to rotate, causing the magnetic suction device to rotate around the rotating seat. When the magnetic suction device rotates to correspond with the transfer box, the telescopic assembly extends and presses down on the magnetic suction device. The magnetic suction device corresponds to the ferromagnetic microneedles in the transfer box, and the magnetic suction device sucks up the ferromagnetic microneedles. The telescopic assembly retracts, and the ferromagnetic microneedles are put into the magnetic suction device.

[0020] S3. When the magnetic suction device is rotated to correspond with the mold core seat, the magnetic suction device corresponds to the micro needle bonding position in the mold core seat. The telescopic component extends and presses down on the magnetic suction device, inserts the ferromagnetic micro needle in the magnetic suction device into the micro needle bonding position, and uses the adhesive curing agent to bond the ferromagnetic micro needle to the mold core seat.

[0021] S4. Repeat steps S2 and S3, and move the mold core seat at equal intervals using a moving stage, so that the ferromagnetic microneedles form a microneedle array inside the mold core seat.

[0022] Optionally, in step S2, when the telescopic component does not press down on the magnetic suction device, the distance between the ferromagnetic microneedles in the transfer box and the magnetic microneedle push rod in the magnetic suction device is greater than 5mm. When the telescopic component presses down on the magnetic suction device, the distance between the ferromagnetic microneedles in the transfer box and the magnetic microneedle push rod is in the range of 1mm-3mm, and the ferromagnetic microneedles in the transfer box are attracted by the magnetic microneedle push rod.

[0023] (III) Beneficial Effects

[0024] The beneficial effects of this invention are:

[0025] This invention discloses a magnetic suction device comprising a push rod cylinder, a fixed cylinder, a magnetic microneedle push rod, a spring, and a push rod fixing plate. Compared to existing technologies, the fixed connection between the push rod cylinder and the fixed cylinder, the coaxial engagement between the magnetic microneedle push rod and the microneedle perforation, and the sliding limit of the push rod fixing plate within the push rod cylinder ensure that the microneedle always moves vertically along the microneedle perforation during suction and lifting, preventing deviation or tilting. The spring is sleeved outside the magnetic microneedle push rod, with its two ends abutting against the push rod fixing plate and the bottom end of the push rod cylinder, respectively. This allows the spring's restoring force to automatically drive the push rod fixing plate upward after a downward press, thereby smoothly guiding the adsorbed microneedle into the microneedle perforation. Simultaneously, the radial constraint of the microneedle perforation effectively ensures the consistency of the microneedle's posture upon entry, while the sliding engagement between the push rod fixing plate and the push rod cylinder provides stable stroke limiting, ensuring precise and controllable displacement during each suction and lifting operation.

[0026] The present invention provides a microneedle mold core manufacturing device, comprising multiple magnetic suction devices. The microneedle mold core manufacturing device includes a support, a connecting seat, a driving assembly, at least two telescopic assemblies, a rotating seat, a mold core seat with adhesive curing agent, a moving stage, and a transfer box with ferromagnetic microneedles. Compared to existing technologies, this invention achieves rapid switching between the magnetic suction devices and the mold core base through the rotational coordination of the connecting seat, rotating seat, driving components, and multiple magnetic suction devices. The telescopic components correspond vertically to the magnetic suction devices, ensuring precise transmission of the downward pressure and preventing offset or empty pressure. Both the mold core base and the rotating seat are located below the rotating seat and vertically correspond to the magnetic suction devices. The moving stage drives the mold core base to move, allowing multiple microneedle bonding positions to align sequentially with the suction devices, achieving array-style parallel operation. Simultaneously, the fixed periphery layout of at least two telescopic components and multiple magnetic suction devices ensures the coordination and consistency of synchronous actions at each station. Structurally, this guarantees the positional accuracy and operational repeatability of the ferromagnetic microneedle suction, transfer, and insertion bonding processes, effectively improving the molding efficiency and arrangement consistency of the microneedle array within the mold core.

[0027] The present invention discloses a method for using a microneedle mold core manufacturing device, comprising the following steps: S1, placing a transfer box and a mold core seat on the periphery of a rotating seat respectively; S2, driving the rotating seat to rotate, causing a magnetic suction device to rotate around the rotating seat. When the magnetic suction device rotates to correspond with the transfer box, a telescopic component extends and presses down on the magnetic suction device, aligning the magnetic suction device with the ferromagnetic microneedles in the transfer box and sucking up the ferromagnetic microneedles. The telescopic component retracts, and the ferromagnetic microneedles are stored in the magnetic suction device; S3, when the magnetic suction device rotates to correspond with the mold core seat, aligning the magnetic suction device with the microneedle bonding position in the mold core seat, the telescopic component extends and presses down on the magnetic suction device, inserting the ferromagnetic microneedles in the magnetic suction device into the microneedle bonding position, and using an adhesive curing agent to bond the ferromagnetic microneedles to the mold core seat; S4, repeating steps S2 and S3, moving the mold core seat at equal intervals via a moving stage, so that the ferromagnetic microneedles form a microneedle array within the mold core seat. Compared to existing technologies, this method involves placing the transfer box and the mold core seat on opposite sides of the rotating seat, respectively. The rotating seat is then driven by a drive assembly, allowing the magnetic suction device to switch between the transfer box and the mold core seat in an orderly manner. This achieves a cyclical connection between the needle picking and insertion processes. The extension and retraction of the telescopic component precisely controls the downward and upward movement of the magnetic suction device, ensuring reliable contact when picking up ferromagnetic microneedles and smooth force application when inserting them into the bonding positions. The moving stage moves the mold core seat at equal intervals, ensuring that each microneedle bonding position corresponds vertically to the magnetic suction device, guaranteeing a uniform arrangement of the ferromagnetic microneedles. Repeatedly executing the needle picking and insertion steps, combined with the stepping displacement of the mold core seat, allows the microneedles to be positioned and bonded sequentially within the mold core seat. This high repeatability ensures the positional accuracy and consistent arrangement of the microneedle array formation. Attached Figure Description

[0028] Figure 1 This is a schematic diagram of the magnetic attraction device according to Embodiment 1 of the present invention;

[0029] Figure 2 for Figure 1 The magnetic attraction device shown is a cross-sectional view taken along the vertical plane containing the magnetic microneedle push rod.

[0030] Figure 3 This is a front view of the microneedle core manufacturing equipment according to Embodiment 2 of the present invention;

[0031] Figure 4 for Figure 3 A cross-sectional view of the microneedle core manufacturing equipment shown, taken along a vertical plane;

[0032] Figure 5 for Figure 3 The diagram shows the structure of the microneedle core manufacturing equipment.

[0033] Explanation of reference numerals in the attached figures

[0034] 1: Magnetic suction device; 11: Push rod cylinder; 12: Fixing cylinder; 13: Magnetic microneedle push rod; 14: Spring; 15: Push rod fixing plate; 16: Microneedle perforation; 17: Ring magnet; 18: Protrusion;

[0035] 2: Bracket; 3: Connector;

[0036] 4: Drive assembly; 41: First driver; 42: External gear;

[0037] 5: Telescopic assembly; 51: Drive cylinder; 52: Cylinder push rod;

[0038] 6: Rotating seat; 61: Bearing component; 62: Seat body; 7: Mold core seat;

[0039] 8: Moving stage; 81: First moving block; 82: Second moving block; 83: X-axis threaded rod; 84: Y-axis threaded rod; 85: Second driver; 86: Third driver; 87: First sliding seat; 88: Second sliding seat;

[0040] 9: Ferromagnetic microneedles; 10: Transfer box. Detailed Implementation

[0041] To better explain and facilitate understanding of the present invention, a detailed description of the invention is provided below with reference to the accompanying drawings and specific embodiments. In this document, directional terms such as "upper," "lower," "left," "right," "front," and "rear" are used interchangeably. Figure 3 The orientation is used as a reference. Among them, "up" refers to the direction near the top of the connecting seat 3, "down" refers to the direction near the moving table 8, "left" refers to the direction near the transfer box 10, "right" refers to the direction near the mold core seat 7, and "front" and "back" refer to the directions perpendicular to the vertical plane where up and down are located, and the horizontal plane where left and right are located.

[0042] To better understand the above technical solutions, exemplary embodiments of the present invention will be described in more detail below with reference to the accompanying drawings. Although exemplary embodiments of the present invention are shown in the drawings, it should be understood that the present invention can be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that the present invention can be understood more clearly and thoroughly, and that the scope of the present invention can be fully conveyed to those skilled in the art.

[0043] Example 1:

[0044] Reference Figure 1 and Figure 2This embodiment proposes a magnetic adsorption device for adsorbing and inserting ferromagnetic microneedles 9. Specifically, in this embodiment, the magnetic adsorption device 1 includes a push rod cylinder 11, a fixed cylinder 12, a magnetic microneedle push rod 13, a spring 14, and a push rod fixing plate 15, as detailed below.

[0045] In this embodiment, the ferromagnetic microneedle 9 refers to a needle-like structure made wholly or partially of a magnetizable ferromagnetic material (such as iron, nickel, cobalt, and their alloys). The ferromagnetic microneedle 9 can be strongly attracted by an external magnetic field (the magnetic force of the magnetic microneedle push rod 13) without the microneedle itself carrying permanent magnetism. The diameter of the ferromagnetic microneedle 9 is in the range of 0.25 mm to 0.3 mm.

[0046] The push rod cylinder 11 is fixed to the top of the fixed cylinder 12 by welding, screwing, or snap-fitting. A microneedle through hole 16 extending vertically through the center of the fixed cylinder 12 is provided. The microneedle through hole 16 is coaxial with the magnetic microneedle push rod 13 and forms a radial constraint on the ferromagnetic microneedle 9. The top end of the magnetic microneedle push rod 13 is fixed to the push rod fixing plate 15 by welding, screwing, or snap-fitting, and the bottom end of the magnetic microneedle push rod 13 passes through the push rod. The bottom of the cylinder 11 extends into the microneedle perforation 16, so that the magnetic microneedle push rod 13 and the microneedle perforation 16 form a coaxial space. The push rod fixing plate 15 is slidably connected to the inside of the push rod cylinder 11. The push rod cylinder 11 provides a guiding space for the push rod fixing plate 15, restricting the push rod fixing plate 15 to slide only in the vertical direction to avoid deflection. The spring 14 is sleeved on the outside of the magnetic microneedle push rod 13. The two ends of the spring 14 elastically abut against the push rod fixing plate 15 and the bottom end of the push rod cylinder 11, respectively.

[0047] When the push rod fixing plate 15 is pressed down, it drives the magnetic microneedle push rod 13 to move downward until its bottom end attracts the ferromagnetic microneedle 9. At this time, the spring 14 is compressed and stores force. After the pressure is released, the restoring force of the spring 14 drives the push rod fixing plate 15 to slide upward, thereby causing the magnetic microneedle push rod 13 with the ferromagnetic microneedle 9 attracted to retract. This allows the ferromagnetic microneedle 9 to enter the microneedle perforation 16 under the guidance of the microneedle perforation 16. The inner wall of the microneedle perforation 16 constrains the upward path of the ferromagnetic microneedle 9 throughout its journey, ensuring that the microneedle always maintains a vertical posture and avoids tilting or deviation. Preferably, the diameter of the microneedle perforation 16 is in the range of 0.35mm-0.45mm, thus limiting the entry of only one ferromagnetic microneedle 9 into the microneedle perforation 16.

[0048] In summary, the fixed connection between the push rod cylinder 11 and the fixed cylinder 12, the coaxial cooperation between the magnetic microneedle push rod 13 and the microneedle perforation 16, and the sliding limit of the push rod fixing plate 15 within the push rod cylinder 11 ensure that the microneedle always moves vertically along the microneedle perforation 16 during the suction and lifting process, avoiding deviation or tilting. The spring 14 is sleeved on the outside of the magnetic microneedle push rod 13, with its two ends abutting against the push rod fixing plate 15 and the bottom of the push rod cylinder 11 respectively. This allows the spring 14 to automatically drive the push rod fixing plate 15 upwards using its restoring force after the downward action, thereby smoothly guiding the adsorbed microneedle into the microneedle perforation 16. Simultaneously, the radial constraint of the microneedle perforation 16 on the microneedle effectively ensures the consistency of the microneedle's posture during entry, while the sliding cooperation between the push rod fixing plate 15 and the push rod cylinder 11 provides stable stroke limit, ensuring precise and controllable displacement during each suction and lifting operation.

[0049] Furthermore, the magnetic microneedle actuator 13 can be a rod-shaped structure that is itself magnetic, thereby enabling it to directly attract ferromagnetic microneedles 9. Alternatively, the magnetic microneedle actuator 13 can also be a rod-shaped structure made of ferromagnetic material, which is not itself magnetic, but is magnetized through the following structure.

[0050] The magnetic attraction device 1 also includes a ring magnet 17. A vertically extending protrusion 18 is provided inside the fixed cylinder 12. A microneedle perforation 16 passes through this protrusion 18, making the protrusion 18 both a carrier for the microneedle perforation 16 and a mounting reference for the ring magnet 17. The ring magnet 17 is disposed within the annular space formed by the protrusion 18 and the inner wall of the fixed cylinder 12. This annular space is coaxially arranged with the microneedle perforation 16, so that the ring magnet 17 surrounds the microneedle perforation 16, forming a symmetrical and uniform magnetic field distribution. The bottom end of the magnetic microneedle push rod 13 is located below the ring magnet 17. When the magnetic microneedle push rod 13 passes through the microneedle perforation 16 in the protrusion 18, the magnetic microneedle... The bottom end of the needle push rod 13 is within the magnetic field coverage area generated by the ring magnet 17, so that the magnetic microneedle push rod 13 is magnetized by the ring magnet 17, thereby forming a stable magnetic attraction force at the bottom end of the magnetic microneedle push rod 13. There is no need to set an additional magnetic core inside the magnetic microneedle push rod 13 or rely on external electromagnetic magnetization, which simplifies the structure of the magnetic microneedle push rod 13. The arrangement of the ring magnet 17 around the protrusion 18 makes full use of the radial space inside the fixed cylinder 12 without increasing the axial height of the device, ensuring the compactness of the overall structure. At the same time, the relative position of the ring magnet 17 and the microneedle hole 16 is fixed, ensuring that the magnetization effect of the magnetic microneedle push rod 13 is consistent each time.

[0051] Furthermore, a chamfer is formed at the bottom of the microneedle perforation 16. This chamfer is located at the edge of the lower opening of the microneedle perforation 16, and the chamfer angle is 30° to 60°. During the process of the ferromagnetic microneedle 9 being attracted by the magnetic microneedle pusher 13 and lifted upward into the microneedle perforation 16, the tip of the ferromagnetic microneedle 9 first contacts the opening at the bottom of the microneedle perforation 16. The chamfer forms a tapered guide surface at the opening with a radial dimension that gradually shrinks from bottom to top. When there is a slight deviation between the axis of the ferromagnetic microneedle 9 and the axis of the microneedle perforation 16, the tip of the ferromagnetic microneedle 9 slides along the tapered guide surface and is gradually guided into the interior of the microneedle perforation 16. This avoids the ferromagnetic microneedle 9 getting stuck at the bottom edge of the perforation or being bent and damaged due to misalignment. At the same time, the chamfer structure forms a smooth transition at the bottom edge of the microneedle perforation 16, reducing the scraping and wear of the surface of the ferromagnetic microneedle 9 by the sharp edge and protecting the surface integrity of the ferromagnetic microneedle 9.

[0052] Furthermore, the annular magnet 17 surrounds the microneedle perforation 16, and its magnetization effect is concentrated at the bottom end of the magnetic microneedle push rod 13. The end face area of ​​the bottom end of the magnetic microneedle push rod 13 is comparable to the end face size of a single ferromagnetic microneedle 9. The resulting attraction force is limited to the bottom end face area, and the magnetic field coverage is narrow, insufficient to act on multiple adjacent ferromagnetic microneedles 9 simultaneously. The ferromagnetic microneedles 9 in the transfer box 10 are discrete, with gaps between them. When the bottom end of the magnetic microneedle push rod 13 moves downward through the microneedle perforation 16, only the ferromagnetic microneedle 9 that is directly opposite the bottom end of the magnetic microneedle push rod 13 and is closest to it is within the range of the strongest magnetic force. The other ferromagnetic microneedles 9 are far from the magnetic core area due to spacing and positional deviations, and the magnetic force they experience is extremely weak, making them unable to be attracted. When the magnetic microneedle push rod 13 attracts the ferromagnetic microneedle 9 and retracts upward, the diameter of the microneedle perforation 16 is larger than the outer diameter of a single ferromagnetic microneedle 9 but smaller than the outer diameter of two ferromagnetic microneedles 9. Only one ferromagnetic microneedle 9 is allowed to pass through at a time. If the bottom end of the magnetic microneedle push rod 13 accidentally attracts a second ferromagnetic microneedle 9, the ferromagnetic microneedle 9 will be blocked and scraped off at the bottom end of the microneedle perforation 16 and cannot enter the microneedle perforation 16 with the first ferromagnetic microneedle 9. This ensures that only the ferromagnetic microneedle 9 that is most firmly attracted is successfully brought in.

[0053] Example 2:

[0054] Reference Figures 3 to 5 This embodiment provides a microneedle mold core manufacturing equipment for manufacturing microneedle array mold cores. Specifically, the microneedle mold core manufacturing equipment in this embodiment includes multiple magnetic suction devices 1, as well as a support 2, a connecting seat 3, a driving component 4, at least two telescopic components 5, a rotating seat 6, a mold core seat 7 with adhesive curing agent, a moving stage 8, and a transfer box 10 with ferromagnetic microneedles 9, as detailed below.

[0055] In this embodiment, the bracket 2 is gantry-shaped, providing a fixed support foundation for the overall structure. The connecting seat 3 is fixedly connected to the bracket 2 by means of snap-fit, welding, or screwing. The bottom of the connecting seat 3 is suspended. The rotating seat 6 is rotatably connected to the bottom of the connecting seat 3. The driving component 4 is connected to the connecting seat 3 and driven by the rotating seat 6. The driving component 4 drives the rotating seat 6 to rotate relative to the connecting seat 3. At least two telescopic components 5 are fixed to the periphery of the connecting seat 3 by means of welding, screwing, or snap-fit. Multiple magnetic suction devices 1 are fixed to the periphery of the rotating seat 6 by means of welding, screwing, or snap-fit. Each telescopic component 5 and its corresponding magnetic suction device 1 are connected along the periphery of the rotating seat 6. The vertical direction is kept relative to each other, so that the extended end of the telescopic component 5 can be accurately aligned with the push rod fixing plate 15 in the magnetic attraction device 1. When the rotating seat 6 drives multiple magnetic attraction devices 1 to rotate synchronously, each magnetic attraction device 1 passes under the telescopic component 5 in sequence. The mold core seat 7 is connected to the upper part of the moving table 8 by means of screwing or snap-fitting. The mold core seat 7 is provided with multiple micro needle bonding positions and filled with adhesive curing agent. The transfer box 10 contains discrete ferromagnetic micro needles 9. The mold core seat 7 and the transfer box 10 are both arranged under the rotating seat 6, and the positions of the transfer box 10 and the mold core seat 7 correspond one-to-one with the different magnetic attraction devices 1 on the periphery of the rotating seat 6 in the vertical direction.

[0056] When the drive assembly 4 drives the rotating seat 6 to rotate, the magnetic suction device 1 revolves around the central axis of the rotating seat 6 to a position corresponding to the transfer box 10. At this position, the telescopic assembly 5 extends and presses down the push rod fixing plate 15 of the magnetic suction device 1. The push rod fixing plate 15 drives the magnetic microneedle push rod 13 to move downward, so that the bottom end of the magnetic microneedle push rod 13 passes through the microneedle hole 16 and contacts the ferromagnetic microneedle 9 in the transfer box 10. The ferromagnetic microneedle 9 is attracted to the bottom end of the magnetic microneedle push rod 13. Then the telescopic assembly 5 retracts, and the magnetic microneedle push rod 13 rises under the return force of the spring 14 and puts the ferromagnetic microneedle 9 into the microneedle hole 16. The rotating seat 6 continues to rotate, so that the magnetic suction device 1 rotates to a position corresponding to the mold core seat 7. At the same time, the moving stage 8 drives the mold core seat 7 to move. Align the first microneedle bonding position in the mold core seat 7 with the magnetic suction device 1. The telescopic component 5 extends again and presses down on the magnetic suction device 1. The magnetic microneedle push rod 13 moves downward to push the ferromagnetic microneedle 9 out from the bottom end of the microneedle perforation 16 and insert it into the microneedle bonding position of the mold core seat 7. The ferromagnetic microneedle 9 is fixed in the mold core seat 7 with the help of adhesive curing agent. Then the telescopic component 5 retracts, the magnetic microneedle push rod 13 rises and resets, and the moving stage 8 drives the mold core seat 7 to move step by step at equal intervals so that the next microneedle bonding position is aligned with the magnetic suction device 1. The rotating seat 6 continues to rotate so that multiple magnetic suction devices 1 pass through the transfer box 10 and the mold core seat 7 in sequence, and perform the needle picking and needle insertion actions in a cycle until the ferromagnetic microneedles 9 are implanted one by one in each microneedle bonding position of the mold core seat 7 and the required microneedle array is formed.

[0057] Moreover, the adhesive curing agent (such as UV-curing adhesive, thermosetting epoxy resin adhesive, two-component acrylate adhesive or hot melt adhesive) is a reagent that fills the interior of the mold core seat 7. Under normal conditions, it has an appropriate viscosity, and under certain conditions (such as UV irradiation or heating), it will cure, so that the ferromagnetic microneedles 9 remain stable in the mold core seat 7. Even if the mold core seat 7 moves, the ferromagnetic microneedles 9 will remain relatively fixed on the cured adhesive curing agent.

[0058] Furthermore, the telescopic assembly 5 includes a drive cylinder 51 and a cylinder push rod 52. The drive cylinder 51 is fixed to the periphery of the connecting seat 3 by welding, screwing, or snap-fitting, so that the drive cylinder 51 remains in a fixed position with the connecting seat 3. The cylinder push rod 52 is drivenly connected to the drive cylinder 51. One end of the cylinder push rod 52 extends out of the drive cylinder 51 and can selectively squeeze the magnetic suction device 1. The extension and retraction of the cylinder push rod 52 are controlled by the drive cylinder 51. When the rotating seat 6 drives the magnetic suction device 1 to rotate to the position corresponding to the telescopic assembly 5, the telescopic assembly 5 and the magnetic suction device 1 are aligned vertically, and the cylinder push rod 52 and the magnetic microneedle push rod 13 remain coaxial. When the cylinder push rod 52 extends, its end is axially aligned with the push rod fixing plate 15 in the magnetic suction device 1 and applies downward pressure. The push rod fixing plate 15 drives the magnetic microneedle push rod 13 to move downward, so that the bottom end of the magnetic microneedle push rod 13 passes through the microneedle perforation 16 to attract or release the ferromagnetic microneedle 9. When the cylinder push rod 52 retracts, it releases the pressure on the push rod fixing plate 15. The magnetic microneedle push rod 13 is reset under the action of the spring 14. The coaxial arrangement of the cylinder push rod 52 and the magnetic microneedle push rod 13 allows the downward pressure to be transmitted along the axial direction of the magnetic microneedle push rod 13, avoiding the generation of radial force. The sliding of the magnetic microneedle push rod 13 in the microneedle perforation 16 remains smooth. The selective extrusion mode of the cylinder push rod 52 allows the telescopic component 5 to apply force only when it is necessary to perform the needle picking or needle insertion action, and to remain in a retracted state when no action is needed, so as to avoid interference with the rotation of the magnetic attraction device 1.

[0059] Furthermore, the drive assembly 4 includes a first driver 41, an internal gear, and an external gear 42. The first driver 41 is fixed inside the connecting seat 3 by welding, screwing, or snapping, forming an integral structure with the connecting seat 3. The drive end of the first driver 41 is fixedly connected to the internal gear, which is located inside the connecting seat 3 and rotates with the drive end. The external gear 42 is fixed to the top of the rotating seat 6 by welding, screwing, or snapping, and the internal gear and external gear 42 maintain a meshing relationship. The rotating seat 6 is rotatably connected to the bottom of the connecting seat 3, and the external gear 42 rotates together with the rotating seat 6. When the first driver 41 is activated, the drive end drives the internal gear to rotate, and the internal gear drives the external gear 42 to rotate through meshing transmission. The external gear 42 drives the rotating seat 6 to rotate relative to the connecting seat 3. The meshing transmission method of the internal gear and the external gear 42 makes the rotation angle precisely controllable. The internal gear is arranged on the connecting seat 3. The outer gear 42 is fixed inside the seat 3 and on the top of the rotating seat 6. The two overlap in the vertical direction, making the space occupied by the drive component 4 compact. The connecting seat 3 forms a protective enclosure for the first driver 41 and the inner gear, preventing foreign objects from entering the meshing area and affecting the transmission accuracy. The outer gear 42 is fixedly connected to the rotating seat 6, so that the rotation of the rotating seat 6 and the rotation of the inner gear are strictly synchronized. After multiple magnetic suction devices 1 are fixed around the rotating seat 6, the angular displacement accuracy of each magnetic suction device 1 as the rotating seat 6 rotates is guaranteed by the gear meshing accuracy, thereby ensuring that each magnetic suction device 1 can accurately stop at the position corresponding to the transfer box 10 or the mold core seat 7. The coaxial relationship between the magnetic micro needle push rod 13 and the micro needle through hole 16 remains stable during rotation, and the deviation of the suction and insertion position of the ferromagnetic micro needle 9 is effectively controlled.

[0060] Furthermore, the rotating seat 6 includes a bearing component 61 and a seat body 62. The bearing component 61 is sleeved on the bottom end of the connecting seat 3, with the inner ring of the bearing component 61 abutting against the outer wall of the bottom end of the connecting seat 3. The seat body 62 is sleeved on the outside of the bearing component 61, with the inner wall of the seat body 62 abutting against the outer ring of the bearing component 61. The connecting seat 3 provides rotational support to the seat body 62 through the bearing component 61. The seat body 62 can rotate freely relative to the connecting seat 3 around its own axis. The bearing component 61 bears radial and axial loads between the connecting seat 3 and the seat body 62. The rotational resistance of the seat body 62 is determined by the rolling friction of the bearing component 61. The rotation process is smooth and without wobble. Preferably, the bearing component 61 is a tapered roller bearing. Several magnetic suction devices 1 are fixed around the periphery of the base 62. When the base 62 rotates, it drives each magnetic suction device 1 to revolve synchronously around the axis of the connecting seat 3. The fixed position of each magnetic suction device 1 relative to the base 62 remains unchanged. The coaxial relationship between the magnetic microneedle push rod 13 and the microneedle through hole 16 is not affected by the rotation of the base 62. The rolling fit of the bearing 61 allows the rotation angle of the base 62 to be precisely controlled by the drive component 4. When the base 62 stops at the predetermined position, there is no gap shaking. Each magnetic suction device 1 maintains a stable posture during the position switching process between the transfer box 10 and the mold core seat 7. The positioning accuracy of the ferromagnetic microneedle 9 in the suction and insertion process is guaranteed by the rotational accuracy of the bearing 61.

[0061] Furthermore, the moving stage 8 includes a first moving block 81, a second moving block 82, an X-axis threaded rod 83, a Y-axis threaded rod 84, a second driver 85, a third driver 86, a first sliding seat 87, and a second sliding seat 88.

[0062] The first moving block 81 is slidably connected to the first sliding seat 87, allowing the first moving block 81 to slide freely relative to the first sliding seat 87 along the first axial direction in the horizontal direction. The second driver 85 is fixed to one end of the first sliding seat 87 and is drivenly connected to the X-axis threaded rod 83. The X-axis threaded rod 83 is threadedly connected to the first moving block 81. When the second driver 85 is started, it drives the X-axis threaded rod 83 to rotate. The X-axis threaded rod 83 drives the first moving block 81 to slide along the first sliding seat 87 through threaded engagement. The top end of the first moving block 81 is fixedly connected to the second sliding seat 88. When the first moving block 81 slides, it drives the second sliding seat 88 to move synchronously.

[0063] The second moving block 82 is slidably connected to the second sliding seat 88, allowing the second moving block 82 to slide freely relative to the second sliding seat 88 along the second axial direction in the horizontal direction. The third driver 86 is fixed to one end of the second sliding seat 88 and is drivenly connected to the Y-axis threaded rod 84. The Y-axis threaded rod 84 is threadedly connected to the second moving block 82. When the third driver 86 is started, it drives the Y-axis threaded rod 84 to rotate. The Y-axis threaded rod 84 drives the second moving block 82 to slide along the second sliding seat 88 through threaded engagement. The mold core seat 7 is fixed to the top of the second moving block 82. When the second moving block 82 slides, it drives the mold core seat 7 to move synchronously.

[0064] The projection of the X-axis threaded rod 83 in the horizontal direction intersects with the projection of the Y-axis threaded rod 84 in the horizontal direction, causing the first axis and the second axis to intersect each other. Through the coordinated drive of the second driver 85 and the third driver 86, the displacement of the first moving block 81 along the first axis and the displacement of the second moving block 82 along the second axis are superimposed, causing the mold core seat 7 to reach different positions in the horizontal plane. The second driver 85 and the third driver 86 respectively control the rotation angle of their respective threaded rods. The threaded engagement between the threaded rods and the moving blocks converts the rotational motion into precise linear displacement. The stage 8 controls the driving amount of the second driver 85 and the third driver 86 according to the set array arrangement parameters. The mold core seat 7 moves sequentially in equal-interval steps. After each step, one microneedle bonding position in the mold core seat 7 aligns with the magnetic suction device 1 in the vertical direction. The magnetic suction device 1 inserts a ferromagnetic microneedle 9 into the current microneedle bonding position. After the mold core seat 7 completes one step, the next microneedle bonding position enters the alignment position. The above process is repeated so that each microneedle bonding position receives the ferromagnetic microneedle 9, and finally a uniformly arranged microneedle array is formed in the mold core seat 7. Preferably, in this embodiment, the first driver 41, the second driver 85 and the third driver 86 are all stepper motors.

[0065] Example 3:

[0066] This embodiment proposes a method for using a microneedle core manufacturing equipment, which includes the following steps.

[0067] S1. Place the transfer box 10 and the mold core seat 7 on the periphery of the rotating seat 6 respectively;

[0068] S2. The drive assembly 4 drives the rotating seat 6 to rotate, so that the magnetic suction device 1 rotates around the rotating seat 6. When the magnetic suction device 1 rotates to correspond with the transfer box 10, the telescopic assembly 5 extends and presses down on the magnetic suction device 1. The magnetic suction device 1 corresponds to the ferromagnetic microneedle 9 in the transfer box 10, and the magnetic suction device 1 sucks up the ferromagnetic microneedle 9. The telescopic assembly 5 retracts, and the ferromagnetic microneedle 9 is put into the magnetic suction device 1.

[0069] S3. When the magnetic suction device 1 is rotated to correspond with the mold core seat 7, the magnetic suction device 1 corresponds to the micro needle bonding position in the mold core seat 7. The telescopic component 5 extends and presses down the magnetic suction device 1, inserts the ferromagnetic micro needle 9 in the magnetic suction device 1 into the micro needle bonding position, and uses the adhesive curing agent to bond the ferromagnetic micro needle 9 to the mold core seat 7.

[0070] S4. Repeat steps S2 and S3, and move the mold core seat 7 at equal intervals by moving the moving stage 8, so that the ferromagnetic micro needles 9 form a micro needle array in the mold core seat 7.

[0071] Specifically, the transfer box 10 and the mold core seat 7 are first placed on the periphery of the rotating seat 6 respectively, so that the transfer box 10 and the mold core seat 7 occupy different positions under the rotating seat 6, and the two correspond to different positions on the periphery of the rotating seat 6 in the vertical direction.

[0072] The drive assembly 4 drives the rotating base 6 to rotate. Multiple magnetic suction devices 1 fixed to the periphery of the rotating base 6 revolve synchronously around the central axis of the rotating base 6 with the base body 62. When the magnetic suction device 1 rotates to the position corresponding to the transfer box 10, the cylinder push rod 52 in the telescopic assembly 5 extends and presses down the push rod fixing plate 15 in the magnetic suction device 1 in the vertical direction. The push rod fixing plate 15 drives the magnetic micro needle push rod 13 to move downward, so that the bottom end of the magnetic micro needle push rod 13 passes through the micro needle hole 16 and contacts the micro needle. The ferromagnetic microneedle 9 in the transfer box 10 is attracted by the magnetic microneedle push rod 13 at the bottom end after being magnetized by the ring magnet 17. Then the cylinder push rod 52 of the telescopic component 5 retracts, and the magnetic microneedle push rod 13 slides upward under the action of the spring 14 and takes the ferromagnetic microneedle 9 into the magnetic attraction device 1 along the guide path of the microneedle hole 16. The chamfer at the bottom end of the microneedle hole 16 corrects its posture to be coaxial with the microneedle hole 16 when the ferromagnetic microneedle 9 enters.

[0073] The rotating seat 6 continues to rotate, moving the magnetic suction device 1 from the transfer box 10 station to the mold core seat 7 station. When the magnetic suction device 1 rotates to the position corresponding to the mold core seat 7, the magnetic suction device 1 and the currently aligned microneedle bonding position in the mold core seat 7 remain aligned in the vertical direction. The cylinder push rod 52 of the telescopic component 5 extends again and presses down the magnetic suction device 1. The magnetic microneedle push rod 13 moves downward to push the ferromagnetic microneedle 9 out from the bottom end of the microneedle through hole 16 and insert it into the microneedle bonding position of the mold core seat 7. The microneedle bonding position of the mold core seat 7 is filled with adhesive curing agent. After the ferromagnetic microneedle 9 is inserted, it is bonded and fixed in the mold core seat 7.

[0074] Repeat the above needle picking and insertion steps. After each needle insertion, the moving stage 8 controls the rotation of the X-axis threaded rod 83 and the Y-axis threaded rod 84 by the second driver 85 and the third driver 86, respectively. This causes the first moving block 81 to slide along the first sliding seat 87 and the second moving block 82 to slide along the second sliding seat 88. This allows the mold core seat 7 to move in equal steps in the horizontal plane according to the set array arrangement spacing. After each step, the next microneedle bonding position in the mold core seat 7 is aligned with the magnetic suction device 1. The rotating seat 6 continues to rotate, causing multiple magnetic suction devices 1 to circulate and alternately pass through the transfer box 10 and the mold core seat 7. Each magnetic suction device 1 picks up and inserts a needle in sequence. The mold core seat 7 moves at equal intervals between each needle insertion, so that the ferromagnetic microneedles 9 are implanted one by one into the microneedle bonding positions in the mold core seat 7 and form a microneedle array evenly arranged at a predetermined interval.

[0075] Furthermore, in step S2, when the telescopic component 5 is not pressing down on the magnetic suction device 1, the distance between the ferromagnetic microneedle 9 in the transfer box 10 and the magnetic microneedle push rod 13 in the magnetic suction device 1 is greater than 5mm. At this time, the distance between the bottom end of the magnetic microneedle push rod 13 and the ferromagnetic microneedle 9 is relatively far. The magnetic force at the bottom end of the magnetic microneedle push rod 13 decreases significantly with the increase of distance. The ferromagnetic microneedle 9 remains stationary in the transfer box 10 and will not be displaced or jump due to the magnetic force, thus avoiding accidental adsorption or mutual adhesion of the ferromagnetic microneedle 9 in the non-absorption state.

[0076] When the telescopic component 5 extends and presses down on the magnetic suction device 1, the push rod fixing plate 15 drives the magnetic microneedle push rod 13 to move downward. The bottom end of the magnetic microneedle push rod 13 extends out of the microneedle perforation 16 and gradually approaches the ferromagnetic microneedle 9 in the transfer box 10. The distance between the ferromagnetic microneedle 9 and the magnetic microneedle push rod 13 decreases to a range of 1mm to 3mm. Within this distance range, the magnetic strength at the bottom end of the magnetic microneedle push rod 13 is sufficient to overcome the weight of the ferromagnetic microneedle 9 itself and the static friction between it and the transfer box 10. The microneedle 9 is effectively attracted by the bottom end of the magnetic microneedle push rod 13, and the distance range ensures that the bottom end of the magnetic microneedle push rod 13 and the ferromagnetic microneedle 9 are appropriately close, which not only ensures reliable attraction force, but also avoids damage caused by hard collision between the ferromagnetic microneedle 9 and the bottom end of the magnetic microneedle push rod 13 due to excessive distance. After the bottom end of the magnetic microneedle push rod 13 forms a stable attraction to the ferromagnetic microneedle 9 within this distance range, the telescopic component 5 retracts, and the magnetic microneedle push rod 13 drives the ferromagnetic microneedle 9 to rise and enter the microneedle perforation 16.

[0077] In the description of this invention, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified.

[0078] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0079] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first and second features are in direct contact, or that they are in indirect contact through an intermediate medium. Furthermore, "above," "over," or "on top" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," or "beneath" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0080] In the description of this specification, the terms "one embodiment," "some embodiments," "embodiment," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0081] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make modifications, alterations, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A magnetic attraction device, characterized in that, It includes a push rod cylinder (11), a fixed cylinder (12), a magnetic micro needle push rod (13), a spring (14), and a push rod fixing plate (15). The push rod cylinder (11) is fixed above the fixed cylinder (12). A microneedle perforation (16) extending vertically through the center of the fixed cylinder (12) is provided. The microneedle perforation (16) is coaxial with the magnetic microneedle push rod (13). The top end of the magnetic microneedle push rod (13) is fixed to the push rod fixing plate (15). The bottom end of the magnetic microneedle push rod (13) passes through the bottom of the push rod cylinder (11) and extends into the microneedle perforation (16). The push rod fixing plate (15) is slidably connected to the inside of the push rod cylinder (11). Spring (14) The spring (14) is sleeved on the outside of the magnetic microneedle push rod (13), and the two ends of the spring (14) are elastically abutted against the bottom end of the push rod fixing plate (15) and the push rod cylinder (11) respectively, so that when the push rod fixing plate (15) is pressed down, the push rod fixing plate (15) drives the magnetic microneedle push rod (13) to move downward until the ferromagnetic microneedle (9) is attracted to the bottom end of the magnetic microneedle push rod (13). When the pressure is released, the restoring force of the spring (14) drives the push rod fixing plate (15) to slide upward, thereby driving the ferromagnetic microneedle into the microneedle perforation (16).

2. The magnetic attraction device as described in claim 1, characterized in that: The magnetic attraction device (1) also includes a ring magnet (17). The fixed cylinder (12) has a protrusion (18) extending vertically inside. The microneedle perforation (16) passes through the protrusion (18). The annular magnet (17) is located in the annular space formed by the protrusion (18) and the inner wall of the fixed cylinder (12). The bottom end of the magnetic microneedle push rod (13) is located below the annular magnet (17), so that the magnetic microneedle push rod (13) is magnetized by the annular magnet (17).

3. The magnetic attraction device as described in claim 1, characterized in that: The bottom end of the microneedle perforation (16) is chamfered, and the chamfer angle is 30°-60°.

4. A microneedle mold core manufacturing device, comprising a plurality of magnetic suction devices as described in any one of claims 1-3, characterized in that: The microneedle core manufacturing equipment includes a support (2), a connecting seat (3), a drive assembly (4), at least two telescopic assemblies (5), a rotating seat (6), a core seat with adhesive curing agent (7), a moving stage (8), and a transfer box (10) with ferromagnetic microneedles (9). The connecting seat (3) is fixedly connected to the bracket (2), the rotating seat (6) is rotatably connected to the bottom of the connecting seat (3), the driving component (4) is connected to the connecting seat (3), and the driving component (4) is driven connected to the rotating seat (6). At least two telescopic components (5) are fixed to the periphery of the connecting seat (3), and multiple magnetic suction devices (1) are fixed to the periphery of the rotating seat (6). The telescopic components (5) and the magnetic suction devices (1) are vertically aligned. The mold core seat (7) is connected above the moving platform (8), and the mold core seat (7) and the transfer box (10) are both located below the rotating seat (6), so that the mold core seat (7) and the transfer box (10) can be vertically aligned with different magnetic suction devices (1). The rotating seat (6) is driven to rotate by the driving component (4), which in turn drives the magnetic suction device (1) to rotate, so that the magnetic suction device (1) can correspond with the mold core seat (7) and the transfer box (10). The magnetic suction device (1) is extended and pressed down by the telescopic component (5), so that when the magnetic suction device (1) corresponds with the transfer box (10), the magnetic suction device (1) adsorbs the ferromagnetic micro needles (9). When the magnetic suction device (1) corresponds with the mold core seat (7), the moving stage (8) drives the mold core seat (7) to move. The magnetic suction device (1) inserts the ferromagnetic micro needles (9) into and adheres them to multiple micro needle bonding positions of the mold core seat (7), thereby forming a micro needle array in the mold core seat (7).

5. The microneedle core manufacturing equipment as described in claim 4, characterized in that: The telescopic assembly (5) includes a drive cylinder (51) and a cylinder push rod (52); The drive cylinder (51) is fixed to the periphery of the connecting seat (3). The cylinder push rod (52) is driven to connect with the drive cylinder (51), so that one end of the cylinder push rod (52) extends out of the drive cylinder (51) and selectively squeezes the magnetic suction device (1). When the telescopic component (5) corresponds to the magnetic suction device (1), the cylinder push rod (52) and the magnetic microneedle push rod (13) are coaxial.

6. The microneedle core manufacturing equipment as described in claim 4, characterized in that: The drive assembly (4) includes a first driver (41), an internal gear, and an external gear (42). The first driver (41) is fixed inside the connecting seat (3), and the driving end of the first driver (41) is fixedly connected to the internal gear. The internal gear meshes with the external gear (42), and the external gear (42) is fixed on the top of the rotating seat (6). The internal gear is driven to rotate by the first driver (41), thereby driving the rotating seat (6) to rotate.

7. The microneedle core manufacturing equipment as described in claim 4, characterized in that: The rotating seat (6) includes a bearing component (61) and a seat body (62). The bearing component (61) is sleeved on the bottom end of the connecting seat (3), and the seat body (62) is sleeved on the outside of the bearing component (61). Several magnetic attraction devices (1) are fixed around the seat body (62).

8. The microneedle core manufacturing equipment as described in claim 4, characterized in that: The moving stage (8) includes a first moving block (81), a second moving block (82), an X-axis threaded rod (83), a Y-axis threaded rod (84), a second driver (85), a third driver (86), a first sliding seat (87), and a second sliding seat (88); The first moving block (81) is slidably connected to the first sliding seat (87), the second driver (85) is fixed to one end of the first sliding seat (87), and the second driver (85) is driven connected to the X-axis threaded rod (83), the X-axis threaded rod (83) is threadedly connected to the first moving block (81), and the top end of the first moving block (81) is fixedly connected to the second sliding seat (88). The second moving block (82) is slidably connected to the second sliding seat (88), the third driver (86) is fixed to one end of the second sliding seat (88), and the third driver (86) is driven to connect with the Y-axis threaded rod (84), the Y-axis threaded rod (84) is threaded to the second moving block (82), and the mold core seat (7) is fixed to the top of the second moving block (82); The projection of the X-axis threaded rod (83) in the horizontal direction intersects with the projection of the Y-axis threaded rod (84) in the horizontal direction. Driven by the second driver (85) and the third driver (86), the mold core seat (7) moves at equal intervals in the horizontal direction, forming multiple microneedle bonding positions in the mold core seat (7). The ferromagnetic microneedles (9) inserted by the magnetic suction device (1) into the microneedle bonding positions form an array.

9. A method of using a microneedle core manufacturing device, comprising the microneedle core manufacturing device according to any one of claims 4-8, characterized in that, Includes the following steps: S1. Place the transfer box (10) and the mold core seat (7) on the periphery of the rotating seat (6) respectively; S2. The drive assembly (4) drives the rotating seat (6) to rotate, so that the magnetic suction device (1) rotates around the rotating seat (6). When the magnetic suction device (1) rotates to correspond with the transfer box (10), the telescopic assembly (5) extends and presses down the magnetic suction device (1). The magnetic suction device (1) corresponds to the ferromagnetic microneedle (9) in the transfer box (10), and the magnetic suction device (1) sucks up the ferromagnetic microneedle (9). The telescopic assembly (5) retracts, and the ferromagnetic microneedle (9) is put into the magnetic suction device (1). S3. When the magnetic suction device (1) is rotated to correspond with the mold core seat (7), the magnetic suction device (1) corresponds to the micro needle bonding position in the mold core seat (7). The telescopic component (5) extends and presses down the magnetic suction device (1), inserts the ferromagnetic micro needle (9) in the magnetic suction device (1) into the micro needle bonding position, and uses the adhesive curing agent to bond the ferromagnetic micro needle (9) to the mold core seat (7). S4. Repeat steps S2 and S3, and move the core holder (7) at equal intervals by moving the stage (8) so that the ferromagnetic microneedles (9) form a microneedle array in the core holder (7).

10. The method of using the microneedle core manufacturing equipment as described in claim 9, characterized in that: In step S2, when the telescopic component (5) does not press down on the magnetic suction device (1), the distance between the ferromagnetic microneedles (9) in the transfer box (10) and the magnetic microneedle push rod (13) in the magnetic suction device (1) is greater than 5mm. When the telescopic component (5) presses down on the magnetic suction device (1), the distance between the ferromagnetic microneedles (9) in the transfer box (10) and the magnetic microneedle push rod (13) is within the range of 1mm-3mm. The ferromagnetic microneedles (9) in the transfer box (10) are attracted by the magnetic microneedle push rod (13).

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