Delivery device for the digestive tract, ablation treatment device and ablation treatment system

Abstract

A delivery device, an ablation treatment device and an ablation treatment system for a digestive tract, comprising: an outer catheter; a middle catheter rotatably arranged relative to the outer catheter; the middle catheter comprising a front section middle catheter, a rear section middle catheter and a middle catheter connecting portion, the front section middle catheter having a smaller hardness than the rear section middle catheter; a hardness adjusting structure comprising a medium passage and a medium filling cavity in communication with the medium passage, the medium filling cavity at least partially surrounding the middle catheter in a circumferential direction, the medium filling cavity spanning the middle catheter connecting portion in a front-rear direction; the medium filling cavity having a filled working state and an unfilled working state, when a medium is injected into the medium filling cavity through the medium passage, the medium filling cavity is in the filled working state, the medium filling cavity radially expands between the middle catheter and the outer catheter, when the medium filling cavity is in the unfilled working state, the medium filling cavity radially contracts between the middle catheter and the outer catheter.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a delivery device, ablation therapy device, and ablation therapy system for the digestive tract. Background Technology

[0002] In existing technologies, delivery devices for the digestive tract must first pass through the patient's pharynx, then through the esophagus, cardia, and stomach before entering the duodenum via the pylorus. Because these devices need to pass through the pharynx, esophagus, and duodenum, most components are designed as flexible parts to protect these areas. However, once the tip of the delivery device enters the stomach, while the flexible parts effectively protect the pharynx and esophagus, they do not facilitate the device's smooth entry into the pylorus.

[0003] In existing technologies, to facilitate the smooth passage of the delivery device through the pylorus, a stiffness adjustment structure is also provided. For example, CN202510646846.0 discloses a gastric bypass stent delivery device. To protect human tissue, its outer tube, internal sliding rod set inside the outer tube, and receiving tube set at the front end are all relatively flexible. To transfer force from the rear end of the outer tube to the receiving tube at the front end, a stiffness adjuster is also provided. The first adjusting tube is sleeved on the second adjusting tube, forming an outer sleeve cavity between the first and second adjusting tubes. The second adjusting tube is sleeved on the outer tube. When the outer sleeve cavity is filled with air, the gastric bypass stent delivery device... The gastric bypass stent delivery device is in a flexible state when the inner lumen of the outer tube is evacuated, and in a rigid state. However, this type of gastric bypass stent delivery system has a complex structure. In order to transmit the force from the rear end of the outer tube to the front end of the receiving tube, the stiffness adjuster spans almost the entire outer tube. This means that the outer tube can only be strengthened or reduced in overall stiffness. This is not conducive to the protection of human tissue when the stiffness is strengthened. Due to its structure, this type of gastric bypass stent delivery device only strengthens its stiffness when passing through the pylorus. In order to avoid harming the patient when passing through other parts, it often does not strengthen its stiffness. It is not suitable for scenarios where it is necessary to enhance torque transmission in flexible parts such as the duodenum.

[0004] Therefore, how to design a delivery device for the digestive tract that has strong torque transmission and minimizes harm to patients is a goal explored by those skilled in the art. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to provide a delivery device, an ablation therapy device, and an ablation therapy system for the digestive tract.

[0006] To solve the above technical problems, the technical solution adopted in the first aspect of the present invention is as follows: A delivery device for the digestive tract includes: A slender external catheter; A slender central conduit, wherein an outer conduit is sleeved on the central conduit and the central conduit is rotatably disposed relative to the outer conduit; the central conduit includes at least a front central conduit located at the front and a rear central conduit located at the rear, the rear end of the front central conduit being connected to the front end of the rear central conduit to form a central conduit connecting portion, and the hardness of the front central conduit being less than the hardness of the rear central conduit; A hardness adjustment structure includes a medium channel located between the middle conduit and the outer conduit and extending in the front-back direction, and a medium filling cavity connected to the medium channel. The medium filling cavity is located between the middle conduit and the outer conduit and at least partially surrounds the middle conduit in the circumferential direction. The medium filling cavity crosses the middle conduit connection portion in the front-back direction. The medium filling cavity has a filled working state and an unfilled working state. When medium is injected into the medium filling cavity through the medium channel, the medium filling cavity is in the filled working state, and the medium filling cavity expands radially between the middle conduit and the outer conduit. When the medium filling cavity is in the unfilled working state, the medium filling cavity contracts radially between the middle conduit and the outer conduit.

[0007] In some embodiments, the media-filled cavity extends forward to the rear portion of the front section of the catheter, and the media-filled cavity extends rearward to the front portion of the rear section of the catheter.

[0008] In some embodiments, the medium filling cavity is a balloon arranged around the inner surface of the outer catheter. The balloon is fixedly connected to the outer catheter. When the balloon changes from the unfilled working state to the filled working state, the balloon expands inward until it contacts the middle catheter.

[0009] In some embodiments, the medium channel is a groove formed in the inner wall of the external conduit and extending in the front-back direction.

[0010] In some embodiments, the conduit is composed of at least three segments connected in sequence, the hardness of each conduit segment decreasing sequentially from back to front, and each conduit connection is provided with a medium filling cavity.

[0011] In some embodiments, the middle conduit is a braided tube, the fabric density of the front section of the middle conduit is less than the fabric density of the rear section of the middle conduit, and / or, the middle conduit is a ribbed metal tube, the rib density of the front section of the middle conduit is greater than the rib density of the rear section of the middle conduit, and / or, the middle conduit is a spring-loaded metal tube.

[0012] In some embodiments, when in the filling working state, the hardness of the portion of the front conduit that does not surround the medium filling cavity, the middle conduit that surrounds the medium filling cavity, and the portion of the rear conduit that does not surround the medium filling cavity increases sequentially in the front-rear direction.

[0013] In some embodiments, the hardness adjustment structure further includes an inlet for the medium to pass through, the inlet being disposed at the proximal end of the delivery device for the digestive tract, the inlet communicating with the medium channel, the inlet drawing the medium outward when transitioning from the filled working state to the unfilled working state, and / or, when transitioning from the unfilled working state to the filled working state, the inlet feeding the medium inward.

[0014] To solve the above technical problems, the second aspect of the present invention adopts the following technical solution: An ablation therapy device for the digestive tract includes the aforementioned delivery device for the digestive tract, and further includes an ablation component, an operating handle, and a medium pressure source. The ablation component is disposed at the front of the delivery device, and the operating handle is disposed at the rear of the delivery device. The medium pressure source is connected to the medium channel. The operating handle drives the middle catheter to rotate relative to the outer catheter, thereby changing the ablation component between an expansion working state and a contraction working state.

[0015] In some embodiments, the ablation component includes an electrode membrane disposed at the front end of the central catheter.

[0016] To solve the above technical problems, the technical solution adopted in the third aspect of the present invention is as follows: A digestive tract ablation therapy system is characterized in that it includes the digestive tract ablation therapy device as described above, and further includes a signal generator for outputting electrical pulse signals to the ablation component.

[0017] Due to the application of the above technical solution, the present invention has the following advantages compared with the prior art: a. The delivery device for the digestive tract of the present invention reduces the harm to the human body when the delivery device passes through the digestive tract by dividing the central conduit into a front central conduit with lower hardness and a rear central conduit with higher hardness. b. The delivery device for the digestive tract of the present invention, by setting a medium filling cavity, prevents stress abrupt changes at the connection part of the middle tube when in the filling working state, which helps the delivery device to pass through the digestive tract, enhances torque transmission, helps control the rotation of the middle tube relative to the outer tube, and at the same time reduces damage to the digestive tract by retaining the flexibility of the front section of the middle tube. c. The delivery device for the digestive tract of the present invention, when in the filling working state, only undergoes localized hardening, which can enhance torque transmission even in flexible parts such as the duodenum, facilitating operation by medical personnel at the proximal end. Attached Figure Description

[0018] Figure 1 This is a side view of the delivery device for the digestive tract according to Embodiment 1 of the present invention; Figure 2 This is a bottom view of the delivery device for the digestive tract according to Embodiment 1 of the present invention; Figure 3 As shown in Embodiment 1 of the present invention Figure 2 The sectional view along the AA direction is currently in the filling state; Figure 4 for Figure 3 Enlarged view of section C; Figure 5 As shown in Embodiment 1 of the present invention Figure 2 The sectional view along the AA direction is currently in an unfilled working state; Figure 6 for Figure 5 Enlarged view of section D; Figure 7 This is a side view of the delivery device for the digestive tract according to Embodiment 2 of the present invention; Figure 8 This is a bottom view of the delivery device for the digestive tract according to Embodiment 2 of the present invention; Figure 9 As shown in Embodiment 2 of the present invention Figure 8 The sectional view along the BB direction is currently in the filling state; Figure 10 As shown in Embodiment 2 of the present invention Figure 8 The sectional view along the BB direction is currently in an unfilled working state; Figure 11 This is a cross-sectional view of Embodiment 3 of the present invention, which is currently in the filling operation state; Figure 12 This is a schematic diagram of the catheter in Embodiment 4 of the present invention; Figure 13 This is a front view of the catheter in Embodiment 5 of the present invention; Figure 14 This is a side view of the catheter in Embodiment 5 of the present invention; Figure 15 This is a side view of the catheter with its outer layer removed in Embodiment 5 of the present invention; Icon labels: 1-External catheter; 2-Middle catheter; 21-Anterior middle catheter; 22-Rear middle catheter; 23-Middle catheter connection; 24-First segment; 25-Second segment; 26-Third segment; 27-Fourth segment; 31-Media channel; 32-Media filling cavity; 33-Inlet; 34-Outlet; 4-Ablation component; 41-Electrode membrane; 42-Stabilizer; 5-Slit metal tube; 6-Braided tube; 61-Outer layer; 62-Inner layer. Detailed Implementation

[0019] The present invention will be further described below with reference to embodiments. In the description of the present invention, the digestive tract refers to the oral cavity, esophagus, stomach, duodenum, small intestine, large intestine, anus, etc., and the term "proximal" refers to the end closer to the operator, while "distal" refers to the end farther from the operator, such as... Figure 1 As shown in the figure, the left direction is the relative "far end" or "front", and the right direction is the relative "proximal end" or "rear end". The direction closer to the middle tube is "inner", and the direction farther from the middle tube is "outer". The above definition of directions is only for the convenience of describing the present invention and simplifying the description. It is not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation of the present invention.

[0020] Example 1 like Figure 1-6 As shown, the delivery device for the digestive tract in this embodiment includes a slender outer catheter 1, a slender middle catheter 2, and a stiffness adjustment structure.

[0021] Both the outer catheter 1 and the middle catheter 2 extend in the front-to-back direction. The outer catheter 1 is sleeved on the middle catheter 2, and the middle catheter 2 is rotatably arranged relative to the outer catheter 1 to facilitate various operations performed by the user on the middle catheter 2 at the proximal end. The middle catheter 2 includes at least a front section middle catheter 21 located at the front and a rear section middle catheter 22 located at the rear. The rear end of the front section middle catheter 21 is connected to the front end of the rear section middle catheter 22 to form a middle catheter connection part 23. The hardness of the front section middle catheter 21 is less than that of the rear section middle catheter 22. In this embodiment, the middle catheter 2 is specifically divided into two sections, the front section corresponding to the front section middle catheter 21 and the rear section corresponding to the rear section middle catheter 22. The middle catheter 2 is made of spring metal tube. Specifically, the spring in the front section middle catheter 21 is thinner and the spring in the rear section middle catheter 22 is thicker. When the delivery device in this embodiment passes through the human body, the front section middle catheter 21 with lower hardness contacts the tissue first, which is beneficial for the protection of the tissue, while the rear section middle catheter 22 with higher hardness facilitates the transmission of force to the front.

[0022] The hardness adjustment structure includes a media channel 31 located between the middle conduit 2 and the outer conduit 1 and extending in the front-back direction, a media filling cavity 32 connected to the media channel 31, and an inlet 33 for media entry. The media filling cavity 32 is located between the middle conduit 2 and the outer conduit 1 and at least partially surrounds the middle conduit 2 in the circumferential direction. The media filling cavity 32 crosses the middle conduit connection portion 23 in the front-back direction and communicates with the media channel 31 through an outlet 34. By providing the media filling cavity 32 at the middle conduit connection portion 23, stress abrupt changes at this location are avoided, preventing the delivery device from bending at the middle conduit connection portion 23 due to compression of its front end when traveling through the digestive tract.

[0023] Specifically, the medium filling cavity 32 extends forward to the rear of the front section of the middle catheter 21, and extends backward to the front of the rear section of the middle catheter 22. The medium filling cavity 32 is a balloon arranged around the inner surface of the outer catheter 1, and the balloon is fixedly connected to the outer catheter 1.

[0024] The medium channel 31 is a groove formed on the inner wall of the outer conduit 1 and extending in the front-back direction. The inlet 33 is located at the near end of the conveying device and is connected to the medium channel 31. The medium can be gas or liquid.

[0025] The medium filling cavity 32 has a filling working state and an unfilled working state. When medium is injected into the medium filling cavity 32 through the medium channel 31, the medium filling cavity 32 is in the filling working state. The medium filling cavity 32 expands radially between the middle conduit 2 and the outer conduit 1, which can adjust the pressure in the medium filling cavity 32. This results in the hardness of the part of the front middle conduit 21 that does not surround the medium filling cavity 32, the middle conduit 2 that surrounds the medium filling cavity 32, and the part of the rear middle conduit 22 that does not surround the medium filling cavity 32 increasing sequentially in the front-back direction. When the medium filling cavity 32 is in the unfilled working state, the medium filling cavity 32 contracts radially between the middle conduit 2 and the outer conduit 1. When switching from the filling working state to the unfilled working state, the inlet 33 draws the medium outward. When switching from the unfilled working state to the filling working state, the inlet 33 inputs the medium inward. The medium filling cavity 32 expands inward until it contacts the middle conduit 2.

[0026] Example 2 like Figure 7-10As shown, the main difference between this embodiment and embodiment 1 is that in this embodiment, the middle conduit 2 is composed of four segments connected in sequence, namely the first segment 24, the second segment 25, the third segment 26 and the fourth segment 27 from front to back. The hardness of each segment decreases from back to front. Each middle conduit connection 23 is provided with a medium filling cavity 32. In this embodiment, for the first segment 24 to the fourth segment 27, every two adjacent connected segments are the front middle conduit 21 and the rear middle conduit 22. Compared with embodiment 1, this embodiment has better flexibility in both the filling working state and the unfilled working state.

[0027] Example 3 like Figure 11 As shown, the main difference between this embodiment and Embodiment 1 is that this embodiment is a device for ablation therapy of the digestive tract. Based on Embodiment 1, it also includes an ablation component 4, an operating handle (not shown in the figure), and a medium pressure source (not shown in the figure). The ablation component 4 is located at the front of the delivery device, and the operating handle is located at the rear of the delivery device. The medium pressure source is connected to the medium channel 31 through the inlet 33. The operating handle drives the middle catheter 2 to rotate relative to the outer catheter 1, so that the ablation component 4 can switch between an expansion working state and a contraction working state. The ablation component 4 includes an electrode membrane 41 and a support 42. The electrode membrane 41 is located at the front end of the middle catheter 2, that is, the part with the lowest hardness in the entire middle catheter 2. Since the hardness adjustment structure is only located at the middle catheter connection 23, when it is necessary to expand the ablation component 4 in the duodenum and then perform the ablation operation, the medium filling cavity 32 can also be converted to a filling working state to enhance the torque transmission of the middle catheter 2 or the outer catheter 1. Moreover, since the medium filling cavity 32 is only reinforced at the middle catheter connection 23, it has better compliance than the method of reinforcing the entire catheter and can reduce damage to tissues.

[0028] Example 4 like Figure 12 As shown, the main difference between this embodiment and embodiment 1 is that in this embodiment, the middle conduit 2 is a textured metal tube, and the texture density of the front middle conduit 21 is greater than that of the rear middle conduit 22.

[0029] Example 5 like Figure 13-15 As shown, the main difference between this embodiment and embodiment 1 is that in this embodiment, the middle conduit 2 is a braided tube 6, which includes an outer layer 61 and an inner layer 62. The outer layer 61 is a plastic layer, and the inner layer 62 is a metal braided wire. The density of the metal braided wire in the front middle conduit 21 is less than the density of the metal braided wire in the rear middle conduit 22.

[0030] Example 6 The main difference between this embodiment and embodiment 3 is that this embodiment is a digestive tract ablation treatment system, which, based on embodiment 3, also includes a signal generator (not shown in the figure), which is used to output electrical pulse signals to the ablation component 4.

[0031] It is understood that the same or similar parts in the above embodiments can be referred to each other, and the contents not described in detail in some embodiments can be referred to the same or similar contents in other embodiments.

[0032] The above embodiments are only for illustrating the technical concept and features of the present invention, and are intended to enable those skilled in the art to understand the content of the present invention and implement it accordingly. They should not be construed as limiting the scope of protection of the present invention. All equivalent changes or modifications made in accordance with the spirit and essence of the present invention should be covered within the scope of protection of the present invention.

Claims

1. A delivery device for the digestive tract, characterized in that, include: A slender external catheter; A slender central conduit, wherein an outer conduit is sleeved on the central conduit and the central conduit is rotatably disposed relative to the outer conduit; the central conduit includes at least a front central conduit located at the front and a rear central conduit located at the rear, the rear end of the front central conduit being connected to the front end of the rear central conduit to form a central conduit connecting portion, and the hardness of the front central conduit being less than the hardness of the rear central conduit; A hardness adjustment structure includes a medium channel located between the middle conduit and the outer conduit and extending in a front-back direction, and a medium filling cavity connected to the medium channel. The medium filling cavity is located between the middle conduit and the outer conduit and at least partially surrounds the middle conduit in a circumferential direction. The medium filling cavity crosses the middle conduit connection portion in a front-back direction. The medium filling cavity extends forward to the rear part of the front section of the middle conduit and extends backward to the front part of the rear section of the middle conduit. The medium filling cavity has a filled working state and an unfilled working state. When medium is injected into the medium filling cavity through the medium channel, the medium filling cavity is in the filled working state, and the medium filling cavity expands radially between the middle conduit and the outer conduit. When the medium filling cavity is in the unfilled working state, the medium filling cavity contracts radially between the middle conduit and the outer conduit.

2. The delivery device for the digestive tract according to claim 1, characterized in that: The medium filling cavity is a balloon arranged around the inner surface of the outer catheter. The balloon is fixedly connected to the outer catheter. When the balloon changes from the unfilled working state to the filled working state, the balloon expands inward until it contacts the middle catheter.

3. The delivery device for the digestive tract according to claim 1, characterized in that: The medium channel is a groove formed on the inner wall of the outer conduit and extending in the front-back direction.

4. The delivery device for the digestive tract according to claim 1, characterized in that: The conduit consists of at least three segments connected in sequence, with the hardness of each segment decreasing sequentially from back to front, and each conduit connection is provided with a medium filling cavity.

5. The delivery device for the digestive tract according to claim 1, characterized in that: The middle guide tube is a braided tube, and the fabric density of the front section of the middle guide tube is less than that of the rear section of the middle guide tube; or, the middle guide tube is a ribbed metal tube, and the ribbed density of the front section of the middle guide tube is greater than that of the rear section of the middle guide tube; or, the middle guide tube is a spring-loaded metal tube.

6. The delivery device for the digestive tract according to claim 1, characterized in that: When in the filling working state, in the front-to-back direction, the hardness of the portion of the front conduit that does not surround the medium filling cavity, the middle conduit that surrounds the medium filling cavity, and the portion of the rear conduit that does not surround the medium filling cavity increases sequentially.

7. The delivery device for the digestive tract according to claim 1, characterized in that: The hardness adjustment structure further includes an inlet for the medium to enter, the inlet being located at the proximal end of the delivery device for the digestive tract, the inlet communicating with the medium channel, and when switching from the filling working state to the unfilled working state, the inlet draws the medium outward, and / or, when switching from the unfilled working state to the filling working state, the inlet inputs the medium inward.

8. A device for ablation therapy of the digestive tract, characterized in that: It includes a delivery device for the digestive tract as described in any one of claims 1-7, further comprising an ablation component, an operating handle, and a media pressure source. The ablation component is disposed at the front of the delivery device, and the operating handle is disposed at the rear of the delivery device. The media pressure source is connected to the media channel. The operating handle drives the middle catheter to rotate relative to the outer catheter, thereby causing the ablation component to switch between an expansion working state and a contraction working state.

9. The device for digestive tract ablation therapy according to claim 8, characterized in that: The ablation component includes an electrode membrane disposed at the front end of the central catheter.

10. A system for ablation therapy of the digestive tract, characterized in that: It includes the ablation treatment device for the digestive tract as described in claim 8, and further includes a signal generator for outputting electrical pulse signals to the ablation component.

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