An anti-aging essence and a preparation method thereof

Abstract

The application relates to the technical field of cosmetic preparation, and discloses an anti-aging essence and a preparation method thereof, which comprises the following steps: carrying out composite dispersion treatment on a liposoluble repairing component and fullerenes to prepare fullerenes-sterol composite liposome oil phase; mixing water-soluble moisturizing components, basic anti-aging active components and deionized water as a matrix, preparing a water phase basic solution after swelling and dispersion; adding the fullerenes-sterol composite liposome oil phase into the water phase basic solution, sequentially carrying out initial emulsification mixing and homogenization refining treatment, then carrying out uniform gradient cooling to obtain an initial emulsion system; under low-temperature conditions, adding a plurality of polypeptide active components into the initial emulsion and stirring; adding a compounded thickening component into the mixed system, and after complete swelling, the viscosity of the mixed system is regulated to a preset target interval; adding a compounded preservative component into the mixed system, uniformly stirring, then carrying out standing and curing treatment, and finally filtering out the product of the anti-aging essence.

Description

Technical Field

[0001] This invention relates to the field of cosmetic preparation technology, specifically to an anti-aging serum and its preparation method. Background Technology

[0002] With the development of functional skincare technology and the upgrading of consumer demand, multi-effect serums that combine anti-aging, antioxidant, and barrier repair effects have become an important development direction in the industry. The compound application of functional components such as fullerenes, ceramides, phytosterols, and active peptides has become a common technical approach. Currently, the mainstream preparation method for such serums is the conventional high-temperature emulsification process, in which the oil phase and water phase components are heated to high temperatures, mixed and homogenized, and then cooled, thickened, and preservatives are added to obtain the finished product. This is a widely used and common technology in the field of cosmetic preparation.

[0003] However, when the aforementioned conventional high-temperature emulsification process is applied to anti-aging serum systems containing fullerenes, high-melting-point lipid repair components, and active peptides, it faces a core technical bottleneck caused by conflicts in component characteristics. The problem with this system lies in the inherent conflict between the dispersion requirements of lipid-soluble components and the retention requirements of peptide activity: First, fullerene powder has a high surface energy and is very easy to agglomerate and settle in water-based systems, making it difficult to achieve uniform dispersion through conventional emulsification and shearing. High-melting-point fat-soluble components such as ceramides and phytosterols have a strong tendency to crystallize, and the lipid particles formed by ordinary emulsification are uneven in size. They are very easy to crystallize during storage and cooling, making dispersion much more difficult than ordinary low-melting-point moisturizing oils.

[0004] Secondly, active peptides have poor thermal stability. The peptide bond structure and spatial conformation are sensitive to temperature. They are prone to degradation and structural damage under high temperature conditions. The high temperature conditions of conventional emulsification will directly cause the loss of peptide biological activity.

[0005] Given this conflict in component characteristics, existing conventional high-temperature emulsification processes cannot simultaneously ensure both system storage stability and retention of functional component activity. Increasing the emulsification temperature and enhancing homogenization strength to improve the dispersion of lipid-soluble components will significantly exacerbate the degradation and inactivation of peptide active substances, leading to a decrease in product efficacy. Conversely, lowering the preparation temperature and shortening the high-temperature treatment time to retain peptide activity will result in insufficient fullerene dispersion and incomplete melting of lipid-soluble repair components, making the product prone to problems such as agglomeration, sedimentation, and crystallization. During the shelf life, the product is also prone to quality abnormalities such as stratification and precipitation. Therefore, we propose an anti-aging serum and its preparation method. Summary of the Invention

[0006] To solve the above-mentioned technical problems, the present invention provides an anti-aging serum, comprising the following components by weight: Deionized water 72.8–77.0 parts, glycerin 3.2–3.8 parts, panthenol 0.5–0.7 parts, dipotassium glycyrrhizate 0.5–0.7 parts, hydroxypropyl tetrahydropyranotriol 11.5–12.5 parts, carnosine 1.3–1.7 parts, low molecular weight sodium hyaluronate 0.12–0.18 parts, xanthan gum 0.12–0.16 parts, sodium polyacrylate 0.15–0.21 parts, squalane 2.7–3.3 parts, lecithin 0.3–0.4 parts, phytosterols Alcohol 0.22–0.28 parts, cholesterol 0.10–0.14 parts, ceramide NP 0.27–0.33 parts, fullerene 0.018–0.022 parts, hydroxypinazone retinate 0.08–0.12 parts, acetyl hexapeptide-8 0.12–0.18 parts, tripeptide-1 copper 0.18–0.22 parts, 1,2-pentanediol 1.0–1.4 parts, phenoxyethanol 0.5–0.7 parts, ethylhexylglycerol 0.08–0.12 parts.

[0007] A method for preparing an anti-aging serum includes the following steps: Step S1: The lipid-soluble repair component is compounded and dispersed with fullerene to prepare the fullerene-sterol composite liposome oil phase; Step S2: Mix water-soluble moisturizing components, basic anti-aging active components, and deionized water as a matrix, and prepare an aqueous basic solution after swelling and dispersion; Step S3: The oil phase of the fullerene-sterol complex liposome is added to the aqueous base solution, and the initial emulsification and homogenization are carried out in sequence, followed by uniform gradient cooling to obtain the initial emulsion system. Step S4: Under constant low temperature conditions, add a variety of polypeptide active components to the colostrum system and disperse them by low-speed stirring; Step S5: Add the compound thickening component to the dispersed mixture. After the thickening component has completely swollen, adjust the viscosity of the mixture to the preset target range. Step S6: Add the compound preservative components to the mixed system that has been regulated, stir evenly, let it stand for aging, and then filter to obtain the anti-aging essence product.

[0008] Preferably, step S1 includes the following steps: Step S11: Add the weighed squalane and lecithin to the oil phase preparation vessel, turn on the stirring device and control the stirring speed at 80-100 rpm, and continue stirring at room temperature until the lecithin is completely dispersed and dissolved. Step S12: Add phytosterol, cholesterol, and ceramide NP to the oil phase preparation vessel in sequence. Heat the oil phase system in the oil phase preparation vessel to 75-80°C and keep the stirring speed constant at 80-100 rpm. Continue stirring for 25-30 minutes until all lipid-soluble repair components are completely melted and miscible. Step S13: Cool the oil phase system to 45-50℃, add fullerene powder to the oil phase system in three equal portions, and start homogenization after each addition. Set the homogenization speed to 3000-3500 rpm and the duration of each homogenization to 2-3 min. After all the materials are added, stir continuously at 80-100 rpm for 15-20 min at 45-50℃ to obtain the fullerene-sterol composite liposome oil phase.

[0009] Preferably, step S2 includes the following steps: Step S21: Add the weighed deionized water into the aqueous phase preparation vessel, turn on the stirring device and control the stirring speed at 60-80 rpm; add glycerol, panthenol, dipotassium glycyrrhizate and hydroxypropyl tetrahydropyranotriol to the water in the aqueous phase preparation vessel in sequence, and continue stirring until all water-soluble components are completely dissolved. Step S22: Evenly sprinkle low molecular weight sodium hyaluronate onto the liquid surface, maintaining a stirring speed of 60-80 rpm during the sprinkling process; after sprinkling, heat the aqueous phase system in the aqueous phase preparation vessel to 50-55℃, and maintain the stirring speed of the stirring device to continuously stir for 30-35 minutes until the sodium hyaluronate is completely swollen and dispersed to obtain the aqueous phase basic solution.

[0010] Preferably, step S3 includes the following steps: Step S31: The oil phase of the fullerene-sterol complex liposome is pumped into the aqueous base solution through a closed pipeline. During the pumping process, the temperature of the aqueous system is maintained at 50-55℃, and the stirring speed of the aqueous preparation vessel is increased to 120-150 rpm. Step S32: After pumping the material, keep the temperature of the mixing system and the speed of the stirring device constant, and continue stirring for 10 to 15 minutes to complete the initial emulsification; then start the homogenization process, control the speed of the homogenization process at 2800 to 3200 rpm, and the homogenization process for 5 to 8 minutes to obtain the initial emulsion system; Step S33: Start the gradient cooling program and reduce the temperature of the colostrum system to 35-38°C at a rate of 0.8-1°C per minute. Maintain a stirring speed of 80-100 rpm throughout the cooling process.

[0011] Preferably, step S4 includes the following steps: Step S41: When the temperature of the colostrum system is stable in the range of 35-38℃, add acetyl hexapeptide-8, tripeptide-1 copper, and carnosine to the colostrum system in sequence. The interval between adding each polypeptide component is 2-3 minutes. During the addition process, maintain a stirring speed of 60-80 rpm. Step S42: After all the active peptide components have been added, keep the temperature of the colostrum system and the speed of the stirring device constant, and continue stirring for 8 to 10 minutes.

[0012] Preferably, step S5 includes the following steps: Step S51: Mix xanthan gum and sodium polyacrylate evenly according to a preset ratio to obtain a compound thickening powder; Step S52: At a stirring speed of 100-120 rpm, slowly sprinkle the compound thickening powder into the mixing system; after sprinkling, increase the stirring speed of the stirring device to 150-180 rpm and continue stirring for 15-20 minutes until the thickening component is completely swollen; Step S53: Take a sample to test the viscosity of the mixture. Based on the viscosity test results, add thickener solution or deionized water for fine-tuning to control the viscosity of the mixture within the range of 700 to 1000 cps.

[0013] Preferably, step S6 includes the following steps: Step S61: Mix 1,2-pentanediol, phenoxyethanol, and ethylhexylglycerin evenly to obtain a compound preservative solution; Step S62: Add the compounded preservative solution to the mixture while stirring at a speed of 80-100 rpm, and continue stirring for 10-12 minutes. Step S63: Allow the mixture to cool naturally to room temperature, stop the stirring device, and let it stand for 20-24 hours to mature; finally, filter the mixture through a 100-mesh filter to obtain the anti-aging essence product.

[0014] The present invention has the following beneficial effects: (1) This invention constructs a composite liposome system of fullerene, sterols, and ceramides, which effectively improves the tendency of fullerene powder to aggregate and settle in water-based systems. Simultaneously, the homogenized lipid carrier structure reduces the tendency of ceramides and sterols to crystallize and precipitate at low temperatures. This dispersion method enhances the uniformity of the serum system during long-term storage, reduces quality abnormalities such as stratification and sedimentation, and ensures the product's quality stability throughout its shelf life.

[0015] (2) The present invention adopts a process route of low-temperature loading of peptide active substances after gradient cooling, which can avoid degradation, structural damage and activity inactivation of peptide active substances in high-temperature emulsification environment, and retain the bioactivity of each peptide component to the greatest extent. At the same time, the step-by-step intermittent feeding method can achieve uniform distribution of active components in the whole system, avoid the problem of uneven activity distribution caused by local concentration differences, ensure the uniformity of the overall efficacy of the product, reduce the ineffective loss of active ingredients during production and preparation, and improve the comprehensive utilization efficiency of raw materials.

[0016] (3) The present invention adopts a process of adding compound thickening components in steps and then fine-tuning them, which can avoid the problems of clumping and insufficient swelling that occur when the thickening powder comes into rapid contact with the liquid phase, ensuring the uniform dispersion and sufficient swelling of the thickening components, and thus stabilizing the viscosity of the system within the target range. The stable and controllable viscosity range can be adapted to the corresponding introductory application methods, reducing dripping and loss problems during use, improving the user experience and raw material utilization efficiency, while the uniform consistency can also improve the appearance and texture of the product. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the process for preparing an anti-aging serum and its preparation method according to the present invention. Detailed Implementation

[0019] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0020] Please see Figure 1 This invention relates to an anti-aging serum, comprising the following components by weight: Deionized water 72.8–77.0 parts, glycerin 3.2–3.8 parts, panthenol 0.5–0.7 parts, dipotassium glycyrrhizate 0.5–0.7 parts, hydroxypropyl tetrahydropyranotriol 11.5–12.5 parts, carnosine 1.3–1.7 parts, low molecular weight sodium hyaluronate 0.12–0.18 parts, xanthan gum 0.12–0.16 parts, sodium polyacrylate 0.15–0.21 parts, squalane 2.7–3.3 parts, lecithin 0.3–0.4 parts, phytosterols Alcohol 0.22–0.28 parts, cholesterol 0.10–0.14 parts, ceramide NP 0.27–0.33 parts, fullerene 0.018–0.022 parts, hydroxypinazone retinate 0.08–0.12 parts, acetyl hexapeptide-8 0.12–0.18 parts, tripeptide-1 copper 0.18–0.22 parts, 1,2-pentanediol 1.0–1.4 parts, phenoxyethanol 0.5–0.7 parts, ethylhexylglycerol 0.08–0.12 parts.

[0021] A method for preparing an anti-aging serum includes the following steps: Step S1: The lipid-soluble repair component is compounded and dispersed with fullerene to prepare the fullerene-sterol composite liposome oil phase; Step S2: Mix water-soluble moisturizing components, basic anti-aging active components, and deionized water as a matrix, and prepare an aqueous basic solution after swelling and dispersion; Step S3: The oil phase of the fullerene-sterol complex liposome is added to the aqueous base solution, and the initial emulsification and homogenization are carried out in sequence, followed by uniform gradient cooling to obtain the initial emulsion system. Step S4: Under constant low temperature conditions, add a variety of polypeptide active components to the colostrum system and disperse them by low-speed stirring; Step S5: Add the compound thickening component to the dispersed mixture. After the thickening component has completely swollen, adjust the viscosity of the mixture to the preset target range. Step S6: Add the compound preservative components to the mixed system that has been regulated, stir evenly, let it stand for aging, and then filter to obtain the anti-aging essence product.

[0022] Step S1 includes the following steps: Step S11: Add the weighed squalane and lecithin to the oil phase preparation vessel, turn on the stirring device and control the stirring speed at 80-100 rpm, and continue stirring at room temperature until the lecithin is completely dispersed and dissolved. Step S12: Add phytosterol, cholesterol, and ceramide NP to the oil phase preparation vessel in sequence. Heat the oil phase system in the oil phase preparation vessel to 75-80°C and keep the stirring speed constant at 80-100 rpm. Continue stirring for 25-30 minutes until all lipid-soluble repair components are completely melted and miscible. Step S13: Cool the oil phase system to 45-50℃, add fullerene powder to the oil phase system in three equal portions, and start homogenization after each addition. Set the homogenization speed to 3000-3500 rpm and the duration of each homogenization to 2-3 min. After all the materials are added, stir continuously at 80-100 rpm for 15-20 min at 45-50℃ to obtain the fullerene-sterol composite liposome oil phase.

[0023] Step S2 includes the following steps: Step S21: Add the weighed deionized water into the aqueous phase preparation vessel, turn on the stirring device and control the stirring speed at 60-80 rpm; add glycerol, panthenol, dipotassium glycyrrhizate and hydroxypropyl tetrahydropyranotriol to the water in the aqueous phase preparation vessel in sequence, and continue stirring until all water-soluble components are completely dissolved. Step S22: Evenly sprinkle low molecular weight sodium hyaluronate onto the liquid surface, maintaining a stirring speed of 60-80 rpm during the sprinkling process; after sprinkling, heat the aqueous phase system in the aqueous phase preparation vessel to 50-55℃, and maintain the stirring speed of the stirring device to continuously stir for 30-35 minutes until the sodium hyaluronate is completely swollen and dispersed to obtain the aqueous phase basic solution.

[0024] Step S3 includes the following steps: Step S31: The oil phase of the fullerene-sterol complex liposome is pumped into the aqueous base solution through a closed pipeline. During the pumping process, the temperature of the aqueous system is maintained at 50-55℃, and the stirring speed of the aqueous preparation vessel is increased to 120-150 rpm. Step S32: After pumping the material, keep the temperature of the mixing system and the speed of the stirring device constant, and continue stirring for 10 to 15 minutes to complete the initial emulsification; then start the homogenization process, control the speed of the homogenization process at 2800 to 3200 rpm, and the homogenization process for 5 to 8 minutes to obtain the initial emulsion system; Step S33: Start the gradient cooling program and reduce the temperature of the colostrum system to 35-38°C at a rate of 0.8-1°C per minute. Maintain a stirring speed of 80-100 rpm throughout the cooling process.

[0025] Step S4 includes the following steps: Step S41: When the temperature of the colostrum system is stable in the range of 35-38℃, add acetyl hexapeptide-8, tripeptide-1 copper, and carnosine to the colostrum system in sequence. The interval between adding each polypeptide component is 2-3 minutes. During the addition process, maintain a stirring speed of 60-80 rpm. Step S42: After all the active peptide components have been added, keep the temperature of the colostrum system and the speed of the stirring device constant, and continue stirring for 8 to 10 minutes.

[0026] Step S5 includes the following steps: Step S51: Mix xanthan gum and sodium polyacrylate evenly according to a preset ratio to obtain a compound thickening powder; Step S52: At a stirring speed of 100-120 rpm, slowly sprinkle the compound thickening powder into the mixing system; after sprinkling, increase the stirring speed of the stirring device to 150-180 rpm and continue stirring for 15-20 minutes until the thickening component is completely swollen; Step S53: Take a sample to test the viscosity of the mixture. Based on the viscosity test results, add thickener solution or deionized water for fine-tuning to control the viscosity of the mixture within the range of 700 to 1000 cps.

[0027] Step S6 includes the following steps: Step S61: Mix 1,2-pentanediol, phenoxyethanol, and ethylhexylglycerin evenly to obtain a compound preservative solution; Step S62: Add the compounded preservative solution to the mixture while stirring at a speed of 80-100 rpm, and continue stirring for 10-12 minutes. Step S63: Allow the mixture to cool naturally to room temperature, stop the stirring device, and let it stand for 20-24 hours to mature; finally, filter the mixture through a 100-mesh filter to obtain the anti-aging essence product.

[0028] One specific application of this embodiment is: This embodiment addresses the conflict between the dispersion requirements of lipid-soluble components and the retention requirements of peptide activity in an anti-aging serum system that simultaneously contains fullerene, high-melting-point lipid repair components, and active peptides. It employs a process route of fullerene pre-composite dispersion, medium-temperature initial emulsification, and gradient cooling followed by low-temperature peptide loading. This approach balances the system's storage stability with the activity of functional components. The parameters of each component and the preparation process are as follows: Raw material ratio The components of the anti-aging serum by mass fraction The specific composition is as follows: squalane 2.0%, lecithin 0.8%, phytosterols 0.5%, cholesterol 0.3%, ceramide NP 0.4%, fullerene 0.2%, deionized water 85.0%, glycerol 5.0%, panthenol 0.5%, dipotassium glycyrrhizate 0.2%, hydroxypropyl tetrahydropyranotriol 1.5%, low molecular weight sodium hyaluronate 0.1%, acetyl hexapeptide-8 0.6%, tripeptide-1 copper 0.5%, carnosine 0.4%, xanthan gum 0.15%, sodium polyacrylate 0.15%, 1,2-pentanediol 0.8%, phenoxyethanol 0.6%, ethylhexylglycerin 0.3%, with the total mass fraction of all components being 100%.

[0029] Preparation process Step S1: Preparation of the oil phase of fullerene-sterol complex liposomes Step S11: Add the weighed squalane and lecithin to a clean oil phase preparation vessel, turn on the stirring device, and set the stirring speed to [missing value]. Controlled at 90 rpm, at room temperature Continue stirring under these conditions until the lecithin is completely dispersed and dissolved, and the system becomes homogeneous and transparent.

[0030] Step S12: Add phytosterols, cholesterol, and ceramide NP sequentially to the oil phase preparation vessel, and start the heating program to raise the temperature of the oil phase system to [temperature value missing]. Maintain stirring speed The stirring time remains unchanged. Until all fat-soluble repair components are completely melted and miscible, and there are no visible particles in the system.

[0031] Step S13: Start the cooling program to cool the oil phase system to [temperature value missing]. Fullerene powder was added to the oil phase system in three equal portions. After each addition, the feed port was closed, and homogenization was started. The homogenization speed was set to [missing value]. Homogenization time After all the ingredients have been added, Under the condition of Stirring at a constant speed Fullerene-sterol complex liposome oil phase was prepared and kept warm for later use.

[0032] Step S2: Preparation of aqueous base solution Step S21: Pour the weighed deionized water into a clean aqueous phase preparation vessel, turn on the stirring device, and set the stirring speed to [missing information]. Control the stirring speed to 70 rpm; add glycerol, panthenol, dipotassium glycyrrhizate, and hydroxypropyl tetrahydropyranotriol to the water in sequence, and continue stirring until all water-soluble components are completely dissolved and the system is clear and free of impurities.

[0033] Step S22: Slowly and evenly sprinkle low molecular weight sodium hyaluronate onto the liquid surface, maintaining a constant temperature and humidity during the sprinkling process. Stirring at a high speed to prevent powder clumping; after spreading, start the heating program to raise the temperature of the aqueous system to [temperature missing]. Maintain stirring speed and continue stirring. The sodium hyaluronate was completely swollen and dispersed until the system was homogeneous and transparent, thus obtaining an aqueous basic solution, which was then kept warm for later use.

[0034] Step S3: Preparation of colostrum system Step S31: Maintain the temperature of the aqueous system The oil phase of the fullerene-sterol complex liposome was slowly pumped into the aqueous base solution through a closed pipeline. During the pumping process, the stirring speed of the aqueous preparation vessel was increased to [missing value]. This ensures that the oil phase is evenly dispersed in the water phase.

[0035] Step S32: After pumping the material, keep the temperature and stirring speed of the mixing system constant and continue stirring. Primary emulsification is completed; then homogenization is initiated, with the homogenization speed set to [specify speed]. Homogenization time This process refines the oil phase particles, resulting in a uniform colostrum system.

[0036] Step S33: Start the gradient cooling program at a cooling rate of The temperature of the colostrum system was lowered at a constant rate. Maintain throughout the cooling process The stirring speed should be adjusted to avoid excessively rapid cooling, which could lead to the crystallization and precipitation of lipid components.

[0037] Step S4: Add peptide active components at low temperature Step S41: When the initial milk system temperature stabilizes at At that time, acetyl hexapeptide-8, tripeptide-1 copper, and carnosine were added to the colostrum system in sequence, with the addition interval for each polypeptide component as follows: Maintain during the feeding process Adjust the stirring speed to ensure that each component is evenly dispersed before adding the next component.

[0038] Step S42: After all the active peptide components have been added, keep the system temperature and stirring speed constant and continue stirring. This ensures that all active components are uniformly dispersed in the system.

[0039] Step S5: System viscosity control Step S51: Mix xanthan gum and sodium polyacrylate evenly in a mass ratio of 1:1 to obtain a compound thickening powder, so as to avoid clumping caused by uneven dispersion of a single thickener.

[0040] Step S52: In Under the stirring speed of [unspecified], slowly and evenly sprinkle the compound thickening powder into the mixing system; after sprinkling, increase the stirring speed to [unspecified]. Continue stirring Continue until the thickening component is completely swollen and there are no visible micelles in the system.

[0041] Step S53: Sample and test the dynamic viscosity of the mixture. Testing conditions: Based on the test results, a small amount of deionized water was added for fine-tuning, ultimately controlling the system viscosity to within a certain range. It falls within the preset target range of 700 to 1000 cps.

[0042] Step S6: Finished Product Preparation Step S61: Mix 1,2-pentanediol, phenoxyethanol, and ethylhexylglycerin in the specified ratio to obtain a compound preservative solution for later use.

[0043] Step S62: In Under the stirring speed, the compound preservative solution is added to the mixing system and stirring is continued. This ensures that the anti-corrosion components are evenly dispersed in the system.

[0044] Step S63: Stop heating and allow the mixture to cool naturally to room temperature. Stop the stirring device and let it stand to mature. The process eliminates tiny air bubbles in the system; finally, the product is filtered through a 100-mesh filter to obtain the anti-aging essence.

[0045] The preferred embodiments of the present invention disclosed above are merely illustrative of the invention. These preferred embodiments do not exhaustively describe all details, nor do they limit the invention to the specific implementations described. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of the invention, thereby enabling those skilled in the art to better understand and utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims

1. An anti-aging serum, characterized in that, The following components are included in parts by weight: Deionized water 72.8–77.0 parts, glycerin 3.2–3.8 parts, panthenol 0.5–0.7 parts, dipotassium glycyrrhizate 0.5–0.7 parts, hydroxypropyl tetrahydropyranotriol 11.5–12.5 parts, carnosine 1.3–1.7 parts, low molecular weight sodium hyaluronate 0.12–0.18 parts, xanthan gum 0.12–0.16 parts, sodium polyacrylate 0.15–0.21 parts, squalane 2.7–3.3 parts, lecithin 0.3–0.4 parts, phytosterols Alcohol 0.22–0.28 parts, cholesterol 0.10–0.14 parts, ceramide NP 0.27–0.33 parts, fullerene 0.018–0.022 parts, hydroxypinazone retinate 0.08–0.12 parts, acetyl hexapeptide-8 0.12–0.18 parts, tripeptide-1 copper 0.18–0.22 parts, 1,2-pentanediol 1.0–1.4 parts, phenoxyethanol 0.5–0.7 parts, ethylhexylglycerol 0.08–0.12 parts.

2. The method for preparing an anti-aging serum according to claim 1, characterized in that: Includes the following steps: Step S1: The lipid-soluble repair component is compounded and dispersed with fullerene to prepare the fullerene-sterol composite liposome oil phase; Step S2: Mix water-soluble moisturizing components, basic anti-aging active components, and deionized water as a matrix, and prepare an aqueous basic solution after swelling and dispersion; Step S3: The oil phase of the fullerene-sterol complex liposome is added to the aqueous base solution, and the initial emulsification and homogenization are carried out in sequence, followed by uniform gradient cooling to obtain the initial emulsion system. Step S4: Under constant low temperature conditions, add a variety of polypeptide active components to the colostrum system and disperse them by low-speed stirring; Step S5: Add the compound thickening component to the dispersed mixture. After the thickening component has completely swollen, adjust the viscosity of the mixture to the preset target range. Step S6: Add the compound preservative components to the mixed system that has been regulated, stir evenly, let it stand for aging, and then filter to obtain the anti-aging essence product.

3. The method for preparing an anti-aging serum according to claim 2, characterized in that: Step S1 includes the following steps: Step S11: Add the weighed squalane and lecithin to the oil phase preparation vessel, turn on the stirring device and control the stirring speed at 80-100 rpm, and continue stirring at room temperature until the lecithin is completely dispersed and dissolved. Step S12: Add phytosterol, cholesterol, and ceramide NP to the oil phase preparation vessel in sequence. Heat the oil phase system in the oil phase preparation vessel to 75-80°C and keep the stirring speed constant at 80-100 rpm. Continue stirring for 25-30 minutes until all lipid-soluble repair components are completely melted and miscible. Step S13: Cool the oil phase system to 45-50℃, add fullerene powder to the oil phase system in three equal portions, and start homogenization after each addition. Set the homogenization speed to 3000-3500 rpm and the duration of each homogenization to 2-3 min. After all the materials are added, stir continuously at 80-100 rpm for 15-20 min at 45-50℃ to obtain the fullerene-sterol composite liposome oil phase.

4. The method for preparing an anti-aging serum according to claim 2, characterized in that: Step S2 includes the following steps: Step S21: Add the weighed deionized water into the aqueous phase preparation vessel, turn on the stirring device and control the stirring speed at 60-80 rpm; add glycerol, panthenol, dipotassium glycyrrhizate and hydroxypropyl tetrahydropyranotriol to the water in the aqueous phase preparation vessel in sequence, and continue stirring until all water-soluble components are completely dissolved. Step S22: Evenly sprinkle low molecular weight sodium hyaluronate onto the liquid surface, maintaining a stirring speed of 60-80 rpm during the sprinkling process; after sprinkling, heat the aqueous phase system in the aqueous phase preparation vessel to 50-55℃, and maintain the stirring speed of the stirring device to continuously stir for 30-35 minutes until the sodium hyaluronate is completely swollen and dispersed to obtain the aqueous phase basic solution.

5. The method for preparing an anti-aging serum according to claim 2, characterized in that: Step S3 includes the following steps: Step S31: The oil phase of the fullerene-sterol complex liposome is pumped into the aqueous base solution through a closed pipeline. During the pumping process, the temperature of the aqueous system is maintained at 50-55℃, and the stirring speed of the aqueous preparation vessel is increased to 120-150 rpm. Step S32: After pumping the material, keep the temperature of the mixing system and the speed of the stirring device constant, and continue stirring for 10 to 15 minutes to complete the initial emulsification; then start the homogenization process, control the speed of the homogenization process at 2800 to 3200 rpm, and the homogenization process for 5 to 8 minutes to obtain the initial emulsion system; Step S33: Start the gradient cooling program and reduce the temperature of the colostrum system to 35-38°C at a rate of 0.8-1°C per minute. Maintain a stirring speed of 80-100 rpm throughout the cooling process.

6. The method for preparing an anti-aging serum according to claim 2, characterized in that: Step S4 includes the following steps: Step S41: When the temperature of the colostrum system is stable in the range of 35-38℃, add acetyl hexapeptide-8, tripeptide-1 copper, and carnosine to the colostrum system in sequence. The interval between adding each polypeptide component is 2-3 minutes. During the addition process, maintain a stirring speed of 60-80 rpm. Step S42: After all the active peptide components have been added, keep the temperature of the colostrum system and the speed of the stirring device constant, and continue stirring for 8 to 10 minutes.

7. The method for preparing an anti-aging serum according to claim 2, characterized in that: Step S5 includes the following steps: Step S51: Mix xanthan gum and sodium polyacrylate evenly according to a preset ratio to obtain a compound thickening powder; Step S52: At a stirring speed of 100-120 rpm, slowly sprinkle the compound thickening powder into the mixing system; after sprinkling, increase the stirring speed of the stirring device to 150-180 rpm and continue stirring for 15-20 minutes until the thickening component is completely swollen; Step S53: Take a sample to test the viscosity of the mixture. Based on the viscosity test results, add thickener solution or deionized water for fine-tuning to control the viscosity of the mixture within the range of 700 to 1000 cps.

8. The method for preparing an anti-aging serum according to claim 2, characterized in that: Step S6 includes the following steps: Step S61: Mix 1,2-pentanediol, phenoxyethanol, and ethylhexylglycerin evenly to obtain a compound preservative solution; Step S62: Add the compounded preservative solution to the mixture while stirring at a speed of 80-100 rpm, and continue stirring for 10-12 minutes. Step S63: Allow the mixture to cool naturally to room temperature, stop the stirring device, and let it stand for 20-24 hours to mature; finally, filter the mixture through a 100-mesh filter to obtain the anti-aging essence product.

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