A herbicidal composition and a method for preparing the same

Abstract

This invention belongs to the field of weed control technology, specifically relating to a weed control composition and its preparation method. The weed control composition includes a herbicide and an adjuvant. The herbicide includes (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) and glyphosate. This invention precisely combines two herbicides with different mechanisms of action and target sites, resulting in a significant synergistic effect. It effectively solves the technical problems caused by long-term application of existing glyphosate single-agent herbicides, such as strong weed resistance, slow weed killing speed, poor control efficacy against malignant resistant weeds, and short residual effect. Field trials show that the weed control composition of this invention has excellent control effects against glyphosate-resistant malignant weeds such as barnyardgrass and foxtail millet. After application, the weed control efficacy is stable and the residual effect is significantly extended, effectively reducing the frequency of application, lowering plant protection costs and pesticide residues. This aligns with the needs of green, reduced-feed, and efficient agricultural development and is suitable for weed control in farmland and non-cultivated land.

Description

Technical Field

[0001] This invention belongs to the field of weed control technology, specifically relating to a weed control composition and its preparation method. Background Technology

[0002] In modern agricultural production systems, weed control in farmland is a core and crucial technological link in ensuring normal crop growth, improving crop yield and quality, and reducing the risk of pests and diseases in the field. Chemical weeding, with its advantages of high efficiency, convenience, low cost, and suitability for large-scale planting, has become the mainstream method for weed control in farmland and is widely used in the field management of food crops and cash crops.

[0003] Glyphosate has outstanding advantages such as broad spectrum of weed control, stable activity, convenient application, and low cost. At the same time, glyphosate has extremely strong adsorption characteristics in soil, is not easily migrated with soil and water, greatly reducing its risk of pollution to groundwater and surface water. It has relatively good environmental adaptability and has long been widely used in weed control in various types of farmland and non-arable land.

[0004] However, with the continuous, single, and large-scale application of glyphosate year after year, the problem of herbicide resistance in weeds has become increasingly prominent, becoming a core bottleneck restricting its weed-control effectiveness. According to existing research and field monitoring data, more than 60 glyphosate-resistant weeds have been found in more than 30 countries worldwide. Common noxious weeds in domestic farmland, such as crabgrass, foxtail, goosegrass, and fleabane, have all developed varying degrees of resistance to glyphosate, significantly reducing the weed-control effect at conventional application doses. At the same time, the application of glyphosate alone also has obvious technical shortcomings. Its control effect on some broadleaf and deep-rooted weeds is limited, and the residual effect of the herbicide is short-lived. Weeds are prone to recurrence and secondary breeding in the short term after application, requiring multiple applications of the herbicide. This not only increases the cost of field plant protection operations and labor costs, but also exacerbates the accumulation of pesticide residues and the ecological burden on the soil, which does not meet the development needs of modern agriculture for green reduction of pesticides and improvement of quality and efficiency.

[0005] To address the shortcomings of single-agent application of glyphosate, various glyphosate-based herbicidal compositions have been disclosed in the existing technology, which can broaden the spectrum of weed control, prolong the duration of action, and improve weed control efficiency to a certain extent. However, existing compound herbicide systems still have many technical limitations. Most compound formulations are only effective against common sensitive weeds, and their control effect on malignant weeds that have developed cross-resistance to glufosinate and glyphosate is extremely poor. At the same time, some compound herbicidal components have poor compatibility with glyphosate, which easily leads to problems such as stratification, precipitation, and antagonism, resulting in poor stability of compound herbicide formulations. In addition, some compound formulations have unreasonable adjuvant systems, and the dispersants used have poor dispersibility, which makes it impossible to uniformly disperse the two active ingredients, bisphosphonates and glyphosate, in the formulation system. This easily leads to the aggregation and sedimentation of active ingredients, which not only greatly reduces the effective utilization rate of the agent, but also causes uneven efficacy and unstable control in the field. Moreover, some compound formulation adjuvants are costly and have complex preparation processes, and their field application safety is poor, which can easily have adverse effects on surrounding crops and soil microecology, thus limiting their comprehensive application value.

[0006] In summary, there is an urgent need in this field to develop a glyphosate compound herbicide composition that is rationally formulated, has significant synergistic effects, strong resistance to weeds, is safe to apply, has controllable costs, and is compatible with various formulations. Summary of the Invention

[0007] Based on the above technical background, the main objective of this invention is to provide a herbicidal composition and its preparation method to overcome the shortcomings of existing technologies, such as prominent weed resistance, limited herbicidal effect, short duration of action, and poor formulation stability.

[0008] To achieve the aforementioned objectives, the technical solution adopted by this invention includes:

[0009] In a first aspect, the present invention provides a weeding composition comprising a herbicide and an adjuvant.

[0010] The herbicides include (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) and glyphosate.

[0011] The mass ratio of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) to glyphosate is (1-5):1.

[0012] Preferably, in the herbicide, the mass ratio of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) to glyphosate is (1-3):1.

[0013] More preferably, the mass ratio of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) to glyphosate is 2:1.

[0014] (1-Hydroxypropane-1,3-diyl)bis(methylphosphonic acid) is a novel bisphosphonic acid herbicidal active compound (see patent CN121471259A). This compound has excellent herbicidal activity and a unique mechanism of action, which complements the herbicidal mechanism of glyphosate. Adding (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) to glyphosate can solve the shortcomings of existing glyphosate compound products, such as weak control of resistant weeds, poor synergistic effect, insufficient application stability, and short duration of action.

[0015] The (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) has good control effects on barnyard grass, crabgrass, foxtail grass, garland chrysanthemum, amaranth, and lambsquarters. Even with a small amount added, it has excellent control effects on the above-mentioned weeds.

[0016] The mechanism of action of glyphosate is as follows: by inhibiting the activity of 5-enolpyruvylshikimate-3-phosphate synthase in plants, it blocks the shikimate metabolic pathway in plants, thereby hindering the biosynthesis of amino acids, and ultimately causing weeds to wither and die due to the obstruction of protein synthesis.

[0017] Based on the total weight of the herbicidal composition as 100%, the herbicide accounts for 0.1% to 50% of the total weight, and the adjuvant accounts for the remainder.

[0018] Preferably, based on the total weight of the herbicidal composition as 100%, the herbicide accounts for 20% to 40% of the total weight, and the adjuvant accounts for the remainder.

[0019] More preferably, based on the total weight of the herbicidal composition as 100%, the herbicide accounts for 30% of the total weight, and the adjuvant accounts for the remainder.

[0020] Preferably, the additives include dispersants and wetting agents.

[0021] Preferably, the dispersant is selected from one or more of alkyl aryl sulfonate formaldehyde condensates and lignin sulfonates.

[0022] More preferably, the dispersant is a mixture of alkyl aryl sulfonate formaldehyde condensate and sodium lignosulfonate, wherein the mass ratio of alkyl aryl sulfonate formaldehyde condensate to sodium lignosulfonate is (3-7):1. For example, the dispersant is obtained by mixing alkyl aryl sulfonate formaldehyde condensate and sodium lignin sulfonate in a mass ratio of 5:1.

[0023] Preferably, the dispersant accounts for 3 to 10% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0024] More preferably, the dispersant accounts for 4 to 5% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0025] The dispersant and dosage added in this invention can effectively reduce the interfacial tension of the herbicide system, promoting the rapid wetting and uniform dispersion of the two solid herbicidal active particles, (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) and glyphosate, in the solvent system. This effectively prevents the aggregation and sedimentation of the herbicide active ingredient particles, significantly improves the suspension stability and uniformity of the herbicide, ensures the stable quality of the herbicide during storage, and ensures uniform distribution of the herbicide solution during field spraying, maximizing the synergistic effect of the herbicide active ingredients.

[0026] Preferably, the wetting agent is selected from one or more of fatty alcohol polyoxyethylene ether, alkyl glycoside, sodium dodecylbenzene sulfonate, and sulfosuccinate salt.

[0027] The preferred sulfosuccinate salt is sodium diisooctyl sulfosuccinate.

[0028] More preferably, the wetting agent is a mixture of sodium dodecylbenzenesulfonate, fatty alcohol polyoxyethylene ether, and sodium diisooctyl sulfosuccinate, wherein the mass ratio of sodium dodecylbenzenesulfonate to fatty alcohol polyoxyethylene ether is (7-9):(2-4):1.

[0029] For example, the wetting agent is obtained by mixing sodium dodecylbenzenesulfonate, fatty alcohol polyoxyethylene ether, and sodium diisooctyl sulfosuccinate in a mass ratio of 8:3:1.

[0030] Preferably, the wetting agent accounts for 1 to 10% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0031] More preferably, the wetting agent accounts for 1 to 3% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0032] The wetting agent selected in this invention, particularly the wetting agent obtained by mixing sodium dodecylbenzenesulfonate and fatty alcohol polyoxyethylene ether in a certain mass ratio, can effectively reduce the interfacial tension between the herbicide composition and the weed leaves, and improve the wetting, spreading, and penetration ability of the herbicide composition on the surface of weed stems and leaves. Since weed leaves in the field generally have a waxy layer, ordinary herbicide compositions are difficult to adhere to the leaf surface, easily resulting in rolling and runoff. However, this invention, by adding a wetting agent to the herbicide composition, allows the herbicide composition to spread quickly and evenly on the weed leaves, preventing herbicide dripping and waste, promoting the rapid penetration of the herbicide's active ingredients into the weed's waxy layer and into the plant to exert its efficacy, significantly improving the herbicide's utilization rate and actual field control effect, while reducing waste and environmental residue.

[0033] More preferably, the additives also include one or more of the following: antifreeze, defoamer, thickener, adhesive, and disintegrant.

[0034] Preferably, the antifreeze is selected from one or more of ethylene glycol, propylene glycol, sodium chloride, methanol, and ammonia.

[0035] More preferably, the antifreeze is ethylene glycol or propylene glycol.

[0036] Preferably, the antifreeze accounts for 0.1% to 1% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0037] More preferably, the antifreeze accounts for 0.1 to 0.5% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0038] The antifreeze agent and dosage selected in this invention can significantly reduce the freezing point of the aqueous formulation of the herbicidal composition, effectively avoiding problems such as freezing, crystallization, stratification, and demulsification of aqueous formulations, suspensions, and emulsions in low-temperature storage and transportation environments. It also prevents the structure of the formulation from being damaged and the active ingredients from being released and deactivated under low-temperature conditions, thus greatly improving the low-temperature storage stability and environmental adaptability of the herbicidal composition, enabling it to be stored and applied year-round in different climatic regions.

[0039] Preferably, the defoamer is selected from one or more of silicone, butyl phosphate, isobutyl phosphate, and n-octanol.

[0040] More preferably, the defoamer is butyl phosphate, isobutyl phosphate, or silicone.

[0041] Preferably, the defoamer accounts for 0.1 to 0.5% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0042] More preferably, the defoamer accounts for 0.1 to 0.3% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0043] The defoamer and dosage used in this invention can effectively eliminate the large amount of foam generated during the stirring, dilution, and field spraying processes of herbicide formulation preparation. This avoids problems such as uneven mixing of herbicide formulation and poor atomization during spraying caused by foam accumulation. It can ensure the batch stability and filling accuracy of the product production, as well as the uniformity and stability of the atomization effect in the field. It avoids problems such as local missed spraying and reduced efficacy caused by foam obstruction and uneven suspension of the herbicide solution, and further improves the field application effect of the formulation.

[0044] Preferably, the thickener is selected from one or more of xanthan gum, magnesium aluminum silicate, sodium carboxymethyl cellulose, and alginate.

[0045] More preferably, the thickener is xanthan gum.

[0046] Preferably, the thickener accounts for 0.1 to 2% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0047] More preferably, the thickener accounts for 0.1 to 0.3% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0048] This invention, by selecting the aforementioned thickener and limiting its dosage, can effectively adjust the viscosity of herbicide aqueous solutions, avoiding the problems of rapid sedimentation and stratification of solid active particles in formulations such as suspensions and emulsions due to low viscosity. This significantly improves the long-term suspension stability and system homogeneity of herbicides. The added thickener adjusts the system to a certain viscosity, significantly improving the atomization uniformity of the herbicide solution, reducing the drift of fine droplets during spraying, lowering the risk of herbicide drift damage, and enhancing the safety and efficacy stability of herbicides applied in the field.

[0049] Preferably, the adhesive is selected from one or more of polyvinylpyrrolidone, dextrin, and starch.

[0050] More preferably, the adhesive is starch or polyvinylpyrrolidone.

[0051] Preferably, the adhesive accounts for 1 to 10% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0052] More preferably, the adhesive accounts for 1 to 3% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0053] This invention, by adding the aforementioned amount of binder to the herbicide composition, effectively enhances the bonding and adhesion between the active ingredient of the herbicide and the carrier filler, improves the formability and structural density of powdered and granular herbicides, and prevents powdering, breakage, and loss of active ingredients during transportation and handling, ensuring the integrity of the formulation and the uniform and stable content of the active ingredient. Simultaneously, after dilution with water during herbicide application, the binder allows the active ingredient to adhere more persistently to the surface of weed stems and leaves, significantly improving the herbicide's resistance to rain washout and preventing a substantial reduction in efficacy due to washout. This effectively extends the field retention period of the active ingredient, reduces the number of applications, and improves weed control stability.

[0054] Preferably, the disintegrant is selected from one or more of urea, sodium bicarbonate, and citric acid.

[0055] More preferably, the disintegrant is sodium bicarbonate or citric acid.

[0056] Preferably, the disintegrant accounts for 1 to 10% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0057] More preferably, the disintegrant accounts for 2 to 5% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0058] This invention, by selecting the aforementioned raw materials as disintegrants, enables solid pesticides to rapidly absorb water, swell, disintegrate, and disperse during field application, preventing problems such as solid pesticides floating on the water surface or clumping and sinking, which leads to slow disintegration. The disintegrant can quickly break down the structural tension within the solid formulation, promoting uniform dispersion of pesticide particles in water to form a stable suspension. This not only significantly simplifies field application and shortens dissolution and dispersion time but also ensures uniform pesticide concentration, eliminating problems such as phytotoxicity and uneven efficacy caused by excessively high or low local pesticide concentrations. It significantly improves the convenience of field application and the stability of efficacy of solid formulations.

[0059] The herbicide is formulated as one or more of the following: aqueous solution, wettable powder, suspension concentrate, water-dispersible granules, emulsion, or microemulsion.

[0060] In this invention, if the herbicide is in the form of an aqueous solution, suspension, emulsion, or microemulsion, the adjuvant also includes a solvent.

[0061] The solvent accounts for the remainder based on 100% of the total weight of the herbicidal composition.

[0062] The solvent is preferably deionized water.

[0063] In this invention, if the herbicide is in the form of a wettable powder, the adjuvant also includes a carrier.

[0064] The carrier is selected from one or more of ammonium sulfate, anhydrous sodium sulfate, glucose, and bentonite.

[0065] Preferably, the carrier is bentonite.

[0066] The carrier accounts for the remainder based on 100% of the total weight of the herbicidal composition.

[0067] In a second aspect, the present invention provides a method for preparing the herbicidal composition described in the first aspect of the present invention, the method comprising the following steps: Mix the herbicide and adjuvant, and stir until homogeneous to obtain the herbicidal composition.

[0068] According to a preferred embodiment of the present invention, when the formulation of the herbicidal composition is an aqueous solution, the preparation method of the herbicidal composition includes the following steps: Mix the dispersant, antifreeze, wetting agent, defoamer, and solvent, and stir until homogeneous to obtain the final product.

[0069] According to a preferred embodiment of the present invention, when the formulation of the herbicidal composition is a wettable powder, the preparation method of the herbicidal composition includes the following steps: The carrier is crushed, and then the herbicide, antifreeze, wetting agent, binder, disintegrant and crushed carrier are mixed and stirred evenly to obtain the final product.

[0070] According to a preferred embodiment of the present invention, when the formulation of the herbicidal composition is a suspension concentrate, the preparation method of the herbicidal composition includes the following steps: Mix the herbicide, wetting agent, dispersant, thickener, antifreeze, defoamer, and solvent, and stir until homogeneous to obtain the final product.

[0071] The herbicidal composition of the present invention has excellent weed control effect on barnyardgrass and foxtail grass, and has a long-lasting effect and is not prone to recurrence.

[0072] The beneficial effects of this invention are as follows: (1) In this invention, (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) and glyphosate are compounded in a specific ratio. The two active ingredients have complementary weeding mechanisms. Glyphosate inhibits the biosynthesis of amino acids by blocking the shikimic acid metabolic pathway in plants, ultimately causing weeds to wither and die due to the inhibition of protein synthesis. (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) has good control effects on barnyard grass, crabgrass, foxtail, garland chrysanthemum, amaranth, and lambsquarters. The combination of the two can produce a significant synergistic effect. Compared with the shortcomings of glyphosate single agent in the early stage of control of resistant weeds such as crabgrass and foxtail, which are easy to recur in the later stage, this invention adds (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) to glyphosate and limits the mass ratio of the two, so that the weeding composition can act on the weed plants quickly and significantly improve its control ability against glyphosate and glufosinate-resistant malignant weeds.

[0073] The herbicidal composition of this invention achieves a control efficacy of over 70% within 7 days after application, far exceeding the 20% control efficacy of glyphosate alone, significantly improving the early weed-killing speed. Furthermore, the herbicidal composition maintains a stable weed control efficacy of over 95% for 28 days after application, with a significantly extended effective period. This effectively solves the problems of incomplete weed control and secondary weed recurrence caused by conventional herbicides, greatly reducing the frequency of repeated application in the field and delaying the emergence and expansion of resistant weed populations from the source.

[0074] (2) This invention addresses the physicochemical properties of the compound system of bisphosphonic acid compounds and glyphosate by designing suitable adjuvants, thus solving the problems of poor compatibility of existing compound herbicides, which lead to easy stratification, sedimentation, freezing, and foaming of the herbicides. In the adjuvants of this invention, the dispersant used can make the active particles of the two herbicides uniformly dispersed in the system, preventing the herbicide particles from agglomerating and settling, and ensuring the overall uniformity of the formulation; the antifreeze can effectively improve the low-temperature tolerance of the formulation, avoiding freezing, demulsification, and crystallization failure during low-temperature storage and transportation, and greatly expanding the applicable regions and seasons of the herbicides; the thickener can precisely control the viscosity of the herbicides system, inhibit the sedimentation and stratification of the suspension system, and ensure excellent long-term storage stability; the defoamer can effectively eliminate the foam generated during production, preparation, and application, ensuring uniform mixing of the herbicide liquid and stable field atomization effect. The various adjuvants work synergistically. The combination of defoamers and dispersants used in this invention further ensures more uniform spraying of the herbicide solution in the field, preventing herbicide aggregation and sedimentation. Compared to using defoamers or dispersants alone, the combined use of defoamers and dispersants is more beneficial in improving the efficacy and duration of weed control of the herbicide solution. The herbicidal composition of this invention is suitable for various formulations such as aqueous solutions, suspensions, wettable powders, and water-dispersible granules.

[0075] (3) The wetting agent system used in this invention can significantly reduce the surface tension of the herbicide solution, enabling it to quickly wet, spread, and penetrate the waxy stems and leaves of weeds, avoiding the problem of traditional herbicide solutions rolling off and being lost. This significantly increases the leaf surface adsorption and absorption rate of the active ingredients in the herbicide. The combination of wetting agents, dispersants, and defoamers used in this invention can improve the adhesion between the herbicide and the leaves, prevent the herbicide from being washed away, reduce the surface tension of the herbicide solution, and improve the penetration and effectiveness of the herbicide solution into the leaves. Compared with the use of wetting agents, dispersants, or defoamers alone, the herbicide solution using wetting agents, dispersants, and defoamers in combination has a better control effect on weeds. Compared with existing conventional formulations, the herbicide composition of this invention can significantly improve the effective utilization rate of its herbicidal active ingredients. Under the same control effect, it can appropriately reduce the total amount of pesticides applied and the number of applications, reducing pesticide residues and ecological pollution pressure in farmland.

[0076] (4) All adjuvants used in this invention are pesticide-acceptable safe adjuvants. They are non-irritating, residue-free, and friendly to soil and surrounding environment. They have low pesticide drift risk and high crop safety, and can be widely used for weed control in various types of farmland and non-arable land. Attached Figure Description

[0077] Figure 1 The following photographs show the weeding effects of the herbicidal compositions described in Examples 1 to 4 and glyphosate on barnyard grass and foxtail grass after foliar spraying. Figure 1Figure A shows the effect of the herbicide composition of Example 1 7 days after application; Figure F shows the effect of the herbicide composition of Example 1 14 days after application; Figure B shows the effect of the herbicide composition of Example 2 7 days after application; Figure G shows the effect of the herbicide composition of Example 2 14 days after application; Figure C shows the effect of the herbicide composition of Example 3 7 days after application; Figure H shows the effect of the herbicide composition of Example 3 14 days after application; Figure D shows the effect of the herbicide composition of Example 4 7 days after application; Figure I shows the effect of the herbicide composition of Example 4 14 days after application; Figure E shows the effect of glyphosate herbicide 7 days after application; Figure J shows the effect of glyphosate 14 days after application. Detailed Implementation

[0078] The present invention will now be described in detail, and its features and advantages will become clearer and more apparent from these descriptions.

[0079] The present invention provides a herbicidal composition comprising a herbicide and an adjuvant, wherein the herbicide comprises (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) and glyphosate, and the mass ratio of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) to glyphosate is (1-3):1.

[0080] The additives include one or more of the following: dispersants, wetting agents, antifreeze agents, defoamers, thickeners, binders, and disintegrants.

[0081] The dispersant is selected from one or more of alkyl aryl sulfonate formaldehyde condensate and lignin sulfonate; the dispersant accounts for 4 to 5% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0082] The wetting agent is selected from one or more of fatty alcohol polyoxyethylene ether, alkyl glycoside, sodium dodecylbenzene sulfonate, and sulfosuccinate salt; the wetting agent accounts for 1 to 3% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0083] The antifreeze is ethylene glycol or propylene glycol; the antifreeze accounts for 0.1 to 0.5% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0084] The defoamer is butyl phosphate, isobutyl phosphate, or silicone; the defoamer accounts for 0.1 to 0.3% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0085] The thickener is xanthan gum, and it accounts for 0.1 to 0.3% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0086] The adhesive is starch or polyvinylpyrrolidone, and the adhesive accounts for 1 to 3% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0087] The disintegrant is sodium bicarbonate or citric acid; the disintegrant accounts for 2 to 5% of the total weight of the herbicidal composition, which is 100% of the total weight.

[0088] The herbicide is formulated as one or more of the following: aqueous solution, wettable powder, suspension concentrate, water-dispersible granules, emulsion, or microemulsion.

[0089] If the herbicide is formulated as an aqueous solution, suspension, emulsion, or microemulsion, the adjuvant also includes a solvent, wherein the solvent is deionized water. The solvent constitutes the remainder based on 100% of the total weight of the herbicide composition.

[0090] If the herbicide is in the form of a wettable powder, the adjuvant also includes a carrier. The carrier is preferably bentonite, and the carrier constitutes the remainder based on 100% of the total weight of the herbicide composition.

[0091] The preparation method of the above-mentioned herbicidal composition includes the following steps: mixing the herbicide and adjuvant, stirring evenly, to obtain the herbicidal composition.

[0092] Example The present invention is further illustrated below with specific examples. These embodiments are merely illustrative and not intended to limit the scope of the invention. All raw materials used in the embodiments of the present invention are commercially available.

[0093] Example 1 A herbicidal composition comprising: 10g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 4g of sodium lignosulfonate, 0.5g of ethylene glycol, 1g of sodium dodecylbenzenesulfonate, 0.2g of butyl phosphate, and 74.3g of deionized water.

[0094] A method for preparing a herbicidal composition, the method comprising the following steps: weighing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, sodium lignosulfonate, ethylene glycol, sodium dodecylbenzenesulfonate and butyl phosphate, adding them to deionized water, mixing and stirring evenly to obtain an aqueous herbicidal composition.

[0095] Example 2 A herbicidal composition comprising: 10g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 4g of alkylaryl sulfonate formaldehyde condensate, 0.5g of propylene glycol, 5g of sodium dodecylbenzenesulfonate, 0.3g of isobutyl phosphate, and 70.2g of deionized water.

[0096] A method for preparing a herbicidal composition, the method comprising the following steps: weighing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, alkyl aryl sulfonate formaldehyde condensate, propylene glycol, sodium dodecylbenzene sulfonate and isobutyl phosphate, adding them to deionized water, mixing and stirring until homogeneous, to obtain the herbicide composition.

[0097] Example 3 A herbicidal composition comprising: 20g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 4g of alkyl aryl sulfonate formaldehyde condensate, 0.2g of ethylene glycol, 2g of sodium diisooctyl sulfosuccinate, 0.2g of silicone, and 63.6g of deionized water.

[0098] A method for preparing a herbicidal composition, the method comprising the following steps: weighing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, alkyl aryl sulfonate formaldehyde condensate, ethylene glycol, sodium diisooctyl sulfosuccinate and silicone, adding them to deionized water, mixing and stirring until homogeneous, thereby obtaining the herbicide composition.

[0099] Example 4 A herbicidal composition comprising: 30g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 5g of alkylaryl sulfonate formaldehyde condensate, 0.3g of ethylene glycol, 2g of sodium dodecylbenzenesulfonate, 0.2g of silicone, and 52.5g of deionized water.

[0100] A method for preparing a herbicidal composition, the method comprising the following steps: weighing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, alkyl aryl sulfonate formaldehyde condensate, ethylene glycol, sodium dodecylbenzene sulfonate (wetting agent) and silicone, adding them to deionized water, mixing, and stirring evenly to obtain the herbicide composition.

[0101] Example 5 A herbicidal composition comprising: weighing 10g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 0.3g of ethylene glycol, 3g of fatty alcohol polyoxyethylene ether (wetting agent), 2g of polyvinylpyrrolidone, 1g of sodium bicarbonate, 1g of citric acid, and adding 72.7g of bentonite, then mixing and pulverizing.

[0102] A method for preparing a herbicidal composition, the method comprising the following steps: weighing and mixing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, ethylene glycol, fatty alcohol polyoxyethylene ether, polyvinylpyrrolidone, sodium bicarbonate, citric acid and bentonite, thereby obtaining the herbicidal composition.

[0103] Example 6 A herbicidal composition comprising: 10g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 0.3g of ethylene glycol, 2g of sodium dodecylbenzenesulfonate (wetting agent), 1g of xanthan gum, 0.2g of butyl phosphate, and 76.5g of deionized water.

[0104] A method for preparing a herbicidal composition, the method comprising the following steps: weighing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, ethylene glycol, sodium dodecylbenzenesulfonate, xanthan gum and butyl phosphate and adding them to deionized water, stirring and mixing evenly to obtain the herbicidal composition.

[0105] Example 7 Similar to the herbicidal composition described in Example 3, the only difference is that: 20g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 4g of alkyl aryl sulfonate formaldehyde condensate, 0.2g of ethylene glycol, 2g of wetting agent, 0.2g of silicone, and 63.6g of deionized water are weighed. The wetting agent is obtained by mixing sodium dodecylbenzenesulfonate, fatty alcohol polyoxyethylene ether, and sodium diisooctyl sulfosuccinate in a mass ratio of 8:3:1.

[0106] A method for preparing a herbicidal composition, the method comprising the following steps: weighing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, alkyl aryl sulfonate formaldehyde condensate, ethylene glycol, wetting agent and silicone into deionized water, stirring and mixing evenly to obtain the herbicidal composition.

[0107] Example 8 Similar to the herbicidal composition described in Example 3, the only difference is that: 20g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 4g of alkyl aryl sulfonate formaldehyde condensate, 0.2g of ethylene glycol, 2g of wetting agent, 0.2g of silicone, and 63.6g of deionized water are weighed. The wetting agent is obtained by mixing sodium dodecylbenzenesulfonate and sodium diisooctyl sulfosuccinate in a mass ratio of 8:1.

[0108] A method for preparing a herbicidal composition, the method comprising the following steps: weighing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, alkyl aryl sulfonate formaldehyde condensate, ethylene glycol, wetting agent and silicone into deionized water, stirring and mixing evenly to obtain the herbicidal composition.

[0109] Example 9 Similar to the herbicidal composition described in Example 3, the only difference is that: 20g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 4g of dispersant, 0.2g of ethylene glycol, 2g of sodium diisooctyl sulfosuccinate, 0.2g of silicone, and 63.6g of deionized water are weighed. The dispersant is obtained by mixing alkyl aryl sulfonate formaldehyde condensate and sodium lignin sulfonate in a mass ratio of 5:1.

[0110] A method for preparing a herbicidal composition, the method comprising the following steps: weighing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, dispersant, ethylene glycol, sodium diisooctyl sulfosuccinate and silicone, adding them to deionized water, stirring and mixing evenly to obtain the herbicidal composition.

[0111] Comparative Example Comparative Example 1 Similar to the herbicidal composition described in Example 3, except that the herbicidal composition in this comparative example does not include glyphosate. The herbicidal composition comprises: 20g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 4g of sodium lignosulfonate, 0.5g of ethylene glycol, 1g of sodium dodecylbenzenesulfonate, 0.2g of butyl phosphate, and 74.3g of deionized water.

[0112] Comparative Example 2 Similar to the herbicidal composition described in Example 3, except that the herbicidal composition in this comparative example does not include (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid). The herbicidal composition comprises: 20g glyphosate, 4g sodium lignosulfonate, 0.5g ethylene glycol, 1g sodium dodecylbenzenesulfonate, 0.2g butyl phosphate, and 74.3g deionized water.

[0113] Comparative Example 3 Similar to the herbicidal composition described in Example 3, except that this example does not include a wetting agent, and the herbicidal composition comprises: 20g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 4g of alkyl aryl sulfonate formaldehyde condensate, 0.2g of ethylene glycol, 0.2g of silicone, and 65.6g of deionized water.

[0114] A method for preparing a herbicidal composition, the method comprising the following steps: adding (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, alkyl aryl sulfonate formaldehyde condensate, ethylene glycol and silicone to deionized water, stirring and mixing evenly to obtain the herbicidal composition.

[0115] Comparative Example 4 Similar to the herbicidal composition described in Example 3, except that this example does not include a dispersant, and the herbicidal composition comprises: 20g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 0.2g of ethylene glycol, 2g of sodium diisooctyl sulfosuccinate, 0.2g of silicone, and 67.6g of deionized water.

[0116] A method for preparing a herbicidal composition, the method comprising the following steps: adding (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, ethylene glycol, sodium diisooctyl sulfosuccinate and silicone to deionized water, stirring and mixing evenly to obtain the herbicidal composition.

[0117] Comparative Example 5 Similar to the weed control composition described in Example 3, except that: this comparative example does not include an antifoaming agent, and weighs 20g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 4g of alkyl aryl sulfonate formaldehyde condensate, 0.2g of ethylene glycol, 2g of sodium diisooctyl sulfosuccinate, and 63.8g of deionized water.

[0118] A method for preparing a herbicidal composition, the method comprising the following steps: weighing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, alkyl aryl sulfonate formaldehyde condensate, ethylene glycol, sodium diisooctyl sulfosuccinate and silicone, adding them to deionized water, mixing and stirring until homogeneous, thereby obtaining the herbicide composition.

[0119] Comparative Example 6 Similar to the herbicidal composition described in Example 3, except that the amount of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) is reduced. The herbicidal composition comprises: 5g of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), 10g of glyphosate, 4g of alkyl aryl sulfonate formaldehyde condensate, 0.2g of ethylene glycol, 2g of sodium diisooctyl sulfosuccinate, 0.2g of silicone, and 78.6g of deionized water.

[0120] A method for preparing a herbicidal composition, the method comprising the following steps: weighing (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid), glyphosate, alkyl aryl sulfonate formaldehyde condensate, ethylene glycol, sodium diisooctyl sulfosuccinate and silicone, adding them to deionized water, mixing and stirring until homogeneous, thereby obtaining the herbicide composition.

[0121] Experimental Example Experiment Example 1: Weed Control Effect Test The herbicides described in Examples 1-4, glyphosate, and the herbicides described in Comparative Examples 1 and 2 were diluted 100 times with water to obtain herbicide solutions. These solutions were then used as foliar sprays to treat barnyardgrass and foxtail millet weeds at the 2-4 leaf stage. The dosage of the herbicide solution was 100 mL / acre. The efficacy against weeds was investigated 7, 14, and 28 days after application. The results are shown in Table 1. The herbicidal effects of each herbicide composition 7 and 14 days after application are as follows: Figure 1 As shown.

[0122] Table 1 Results of weed control efficacy tests

[0123] As shown in Table 1, the weed control efficacy of the herbicides described in Examples 1-9 against barnyard grass and foxtail grass after foliar spraying was 70-79% after 7 days, 88-98% after 14 days, and 85-95% after 28 days, all higher than that of glyphosate against barnyard grass and foxtail grass. The weed recurrence rate of the herbicides described in Examples 1-9 was less than 10% after 45 days of application, lower than that of glyphosate against barnyard grass and foxtail grass. The weed control efficacy of the herbicides described in this invention was above 70% after 7 days of application, far superior to the 20% efficacy of glyphosate alone. After 14 days, its weed control efficacy was above 89%, with a slight decrease to above 88% after 28 days. Figure 1 As can be seen, the herbicidal composition of the present invention has a better herbicidal effect than glyphosate. The above results indicate that the herbicidal composition of the present invention has excellent herbicidal activity against weeds, with high weed control efficiency. The efficacy of the herbicidal composition against weeds reaches its peak 14 days after application. It also shows that adding (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) to glyphosate results in even better herbicidal activity, exhibiting excellent control effects against glyphosate-resistant weeds such as barnyardgrass and foxtail. Furthermore, the herbicidal composition has good stability, a long-lasting herbicidal effect, and a low weed recurrence rate after 45 days. This herbicidal composition not only reduces the use of glyphosate but also improves the herbicidal efficiency, effectiveness, and persistence of the herbicidal composition. After application, the herbicidal effect against weeds is stable and the residual effect is significantly extended, effectively reducing the frequency of application, lowering plant protection costs, and reducing pesticide residues.

[0124] Compared with Example 3, Comparative Example 1 did not contain glyphosate. The weed control efficacy of Comparative Example 1 at 7 days, 14 days and 28 days was significantly lower than that of Example 3, and its weed recurrence rate at 45 days was much higher than that of Example 3. The above results indicate that the addition of glyphosate has an important impact on the weed control efficacy and weed recurrence rate.

[0125] Compared with Comparative Example 2 and Example 3, the composition of Comparative Example 2 does not include (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid). The weed control efficacy of Comparative Example 2 at 7 days, 14 days, and 28 days was significantly lower than that of Example 3, and its weed recurrence rate at 45 days was much higher than that of Example 3. The above results indicate that the addition of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) can improve the weed control efficacy and reduce the weed recurrence rate. From the weed control effects of Comparative Example 1, Comparative Example 2, and Example 3, it can be seen that (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) and glyphosate have a synergistic effect. The weed control effect and the inhibition of weed recurrence rate when both are added at a specific ratio are significantly higher than the effect of adding (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) or glyphosate alone.

[0126] Compared with Example 3, Comparative Example 3 did not add a wetting agent. The weed control efficacy of Comparative Example 3 at 7 days, 14 days and 28 days was lower than that of Example 3, and its weed recurrence rate at 45 days was much higher than that of Example 3. The above results indicate that adding a wetting agent to the weed control composition is beneficial to improving the weed control efficacy and inhibiting the weed recurrence rate.

[0127] Compared with Example 3, Comparative Example 4 did not add a dispersant. The weed control efficacy of Comparative Example 4 at 7 days, 14 days and 28 days was lower than that of Example 3, and its weed recurrence rate at 45 days was much higher than that of Example 3. The above results indicate that adding a dispersant to the weed control composition is beneficial to improving the weed control efficacy and the inhibition of weed recurrence rate.

[0128] Compared with Example 3, Comparative Example 5 did not add defoamer. The weed control efficacy of Comparative Example 5 at 7 days, 14 days and 28 days was slightly lower than that of Example 3, and its weed recurrence rate at 45 days was slightly higher than that of Example 3. The above results indicate that adding defoamer to the weed control composition has little effect on the weed control efficacy and weed recurrence rate. However, adding defoamer to the weed control composition can slightly improve the weed control efficacy and the inhibition of weed recurrence rate.

[0129] Compared with Example 3, Comparative Example 6 reduced the amount of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid). The weed control efficacy of Comparative Example 5 at 7 days, 14 days, and 28 days was slightly lower than that of Example 3, and its weed recurrence rate at 45 days was slightly higher than that of Example 3. The results show that the amount of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) added affects the weed control efficacy and inhibition effect of the composition.

[0130] The present invention has been described in detail above with reference to specific embodiments and exemplary examples; however, these descriptions should not be construed as limiting the present invention. Those skilled in the art will understand that various equivalent substitutions, modifications, or improvements can be made to the technical solutions and embodiments of the present invention without departing from the spirit and scope of the invention, and all such modifications and improvements fall within the scope of the present invention. The scope of protection of the present invention is defined by the appended claims.

Claims

1. A herbicidal composition, characterized in that, The herbicidal composition includes a herbicide and an adjuvant; The herbicide includes (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) and glyphosate; The mass ratio of (1-hydroxypropane-1,3-diyl)bis(methylphosphonic acid) to glyphosate is (1-5):

1.

2. The herbicidal composition according to claim 1, characterized in that, Based on the total weight of the herbicidal composition as 100%, the herbicide accounts for 0.1% to 50% of the total weight, and the adjuvant accounts for the remainder.

3. The herbicidal composition according to claim 1, characterized in that, The additives include dispersants and wetting agents; The dispersant is selected from one or more of alkyl aryl sulfonate formaldehyde condensates and lignin sulfonates; The dispersant accounts for 3 to 10% of the total weight of the herbicidal composition, which is 100% of the total weight.

4. The herbicidal composition according to claim 3, characterized in that, The wetting agent is selected from one or more of fatty alcohol polyoxyethylene ether, alkyl glycoside, sodium dodecylbenzene sulfonate, and sulfosuccinate salt; The wetting agent accounts for 1 to 10% of the total weight of the herbicidal composition, which is 100% of the total weight.

5. The herbicidal composition according to claim 3, characterized in that, The additives also include one or more of the following: antifreeze, defoamer, thickener, binder, and disintegrant; The antifreeze is selected from one or more of ethylene glycol, propylene glycol, sodium chloride, methanol, and ammonia. The antifreeze accounts for 0.1% to 1% of the total weight of the herbicidal composition, which is 100% of the total weight.

6. The herbicidal composition according to claim 5, characterized in that, The defoamer is selected from one or more of silicone, butyl phosphate, isobutyl phosphate, and n-octanol; The defoamer accounts for 0.1 to 0.5% of the total weight of the herbicidal composition, which is 100% of the total weight.

7. The herbicidal composition according to claim 5, characterized in that, The thickener is selected from one or more of xanthan gum, magnesium aluminum silicate, sodium carboxymethyl cellulose, and alginate; The thickener accounts for 0.1 to 2% of the total weight of the herbicidal composition, which is 100% of the total weight.

8. The herbicidal composition according to claim 5, characterized in that, The adhesive is selected from one or more of polyvinylpyrrolidone, dextrin, and starch; The adhesive accounts for 1 to 10% of the total weight of the herbicidal composition, which is 100% of the total weight.

9. The herbicidal composition according to claim 5, characterized in that, The disintegrant is selected from one or more of urea, sodium bicarbonate, and citric acid; The disintegrant accounts for 1 to 10% of the total weight of the herbicidal composition, which is 100% of the total weight.

10. A method for preparing the herbicidal composition according to any one of claims 1 to 9, characterized in that, The preparation method includes the following steps: Mix the herbicide and adjuvant, and stir until homogeneous to obtain the herbicidal composition.

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