A negative pressure pollution prevention syringe storage box suitable for chemotherapy dispensing in an oncology department

CN122701979APending Publication Date: 2026-09-08黄梦莹
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Patent Information

Application Number
CN202611143242.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-07-30
Publication Date
2026-09-08

AI Technical Summary

Technical Problem

[0004]肿瘤科医护人员配置化疗药物时,两大操作环节易造成细胞毒性药物残留,埋下职业暴露隐患

Benefits of technology

配药作业阶段,将针筒吸附模块组装于针筒外壁。针头穿刺西林瓶瞬间,瓶内压力变化易造成微量药液喷溅;此时气体净化模块同步启动,吸附套侧壁的吸气孔持续负压抽吸,将飞溅药液及时经由软管吸入,再通过微型吸气设备送入多层滤芯仓完成净化处理。转运阶段,针筒收纳盒密闭空间易积聚毒性挥发气体,依托微型吸气设备不间断抽排,降低密封盖体腔体内毒物浓度,规避医护人员职业损伤。

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Abstract

This invention relates to the field of medical equipment technology, and in particular to a negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology departments. The syringe storage box includes a gas purification module installed inside, and a syringe adsorption module installed on the outside of the syringe. The syringe adsorption module includes an adsorption sleeve with evenly distributed suction holes on one side. A flexible tube is connected to the side of the adsorption sleeve, and the other end of the flexible tube is fixedly connected to the gas purification module. During the drug preparation process, the syringe adsorption module is assembled onto the outer wall of the syringe, and the gas purification module is activated simultaneously. The suction holes on the side wall of the adsorption sleeve continuously draw in negative pressure, promptly drawing in splashed medication through the flexible tube. The medication is then sent to a multi-layer filter chamber for purification via a micro-suction device. During transport, the sealed space of the syringe storage box easily accumulates toxic volatile gases. The micro-suction device continuously extracts and removes these gases, reducing the concentration of toxic substances within the sealed cavity and preventing occupational injuries to medical personnel.
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Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology. Background Technology

[0002] When healthcare workers perform routine procedures such as syringe handling, medication verification, label counting, and syringe transfer, they may inhale toxic aerosols through the respiratory tract, posing a continuous low-dose exposure risk. Existing epidemiological surveillance data on hospital-acquired infections have fully confirmed that the urine of healthcare workers who routinely prepare chemotherapy drugs can consistently detect the original chemotherapy drugs or their metabolites. This type of occupational exposure scenario has been clearly listed as a key high-risk item for infection control and occupational health protection in medical institutions.

[0003] According to the relevant standards WS / T856-2025 and WS / T510, the time for storing chemotherapy syringes containing medication in a sealed container should not exceed 2 hours. Currently, most intravenous compounding centers adopt a batch preparation and centralized distribution model, and the storage time for syringes containing medication is mostly 0.5 to 2 hours, which coincides with the peak period of drug residue volatilization.

[0004] When oncology medical staff prepare chemotherapy drugs, two key operational steps can easily lead to cytotoxic drug residues, posing a risk of occupational exposure. First, during the needle puncture of the vial, the rapid pressure fluctuations create numerous microscopic droplets of medication invisible to the naked eye. These droplets easily adhere to the outer cone surface of the syringe's Luer connector, forming nanogram-level cytotoxic drug residues. Second, during drug transport, conventional sealed storage boxes often lack sufficient permeability, preventing the escape of toxic gases from multiple syringes and causing a continuous accumulation of toxic gas concentrations within the box. While this scenario does not pose an immediate risk of drug leakage and contamination, subsequent transport, opening, and verification procedures can easily lead to concentrated occupational exposure. Current conventional protective equipment and operating methods cannot achieve precise control, necessitating the development of more adaptable specialized protective technologies. Therefore, this paper proposes a negative pressure anti-contamination syringe storage box suitable for oncology chemotherapy drug preparation. Summary of the Invention

[0005] The purpose of this invention is to provide a negative pressure anti-contamination syringe storage box suitable for chemotherapy drug preparation in oncology, so as to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, the present invention provides the following technical solution: As an optional solution of the negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology as described in this invention, the negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology includes a syringe storage box, a sealing cover and a gas purification module. A sealing cover is installed on the top of the syringe storage box, and an adaptive limiting component is installed inside the sealing cover; The syringe storage box also has a gas purification module installed inside. The gas purification module has multiple positioning blocks installed inside, and each positioning block has a syringe installed inside. Each syringe has a sealing cap on one side, and a syringe adsorption module is installed on the outside of the syringe. The syringe adsorption module includes an adsorption sleeve, an air intake port, and a flexible tube. The bottom of the adsorption sleeve has an opening, and one side of the adsorption sleeve has evenly distributed air intake ports. The side of the adsorption sleeve is connected to a flexible tube, and the other end of the flexible tube is fixedly connected to a gas purification module. The inner side of the adsorption sleeve is fixedly connected to a docking sleeve, and a docking post is installed at the bottom of the docking sleeve. The bottom of the docking post is fixedly connected to the syringe.

[0007] As an optional solution for the negative pressure anti-pollution syringe storage box adapted for chemotherapy drug preparation in oncology as described in this invention, the absorbent sleeve is made of medical flexible rubber sheet.

[0008] As an optional solution for the negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology as described in this invention, the adaptive limiting component includes a limiting plate, a flexible positioning airbag, and a connecting air tube. The outer side of the limiting plate is fixedly connected to the sealing cover. A uniformly distributed limiting groove is opened on one side of the limiting plate. A flexible positioning airbag is installed inside the limiting plate. A connecting air tube is connected to one side of the flexible positioning airbag, and the other end of the connecting air tube is connected to a gas purification module.

[0009] When oncology medical staff prepare chemotherapy drugs, two key operational steps can easily lead to cytotoxic drug residues, posing a potential occupational exposure hazard. First, during the needle puncture of the vial, the rapid pressure fluctuations inside the vial create numerous microscopic droplets of medication invisible to the naked eye. These droplets easily adhere to the outer cone surface of the syringe's Luer connector, forming nanogram-level cytotoxic drug residues. Second, during drug transport, conventional sealed storage boxes often lack sufficient permeability, preventing the escape of toxic gases volatilized from multiple syringes, causing a continuous accumulation of toxic gas concentrations within the box. While there is no immediate risk of drug leakage and contamination in this scenario, subsequent operations such as transport, opening the vial for use, and drug verification can easily lead to concentrated occupational exposure. This device addresses this by assembling a syringe adsorption module onto the outer wall of the syringe during the drug preparation phase. When the needle punctures the vial, the pressure change inside can easily cause a small amount of medication to splash out. At this moment, the gas purification module activates simultaneously, and the suction port on the side wall of the adsorption sleeve continuously draws in the splashed medication through the tubing, and then through the micro-suction device into the multi-layer filter chamber for purification. During the transport stage, the sealed space of the syringe storage box can easily accumulate toxic volatile gases. Relying on the micro-suction device to continuously extract and remove these gases reduces the concentration of toxic substances in the sealed cavity, thus preventing occupational injuries to medical personnel.

[0010] As an optional solution for the negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology as described in this invention, the gas purification module includes a placement shell, a micro-inhalation device, and air tubes. A groove is provided on the top of the placement shell, and multiple positioning blocks are arranged in the groove. The micro-inhalation device is installed inside the placement shell. The input end of the micro-inhalation device is connected to a branch pipe, and the other end of the branch pipe is connected to a uniformly distributed air tube. The other end of each air tube is connected to a cable retraction mechanism. The cable retraction mechanism is fixedly connected to the placement shell on the outside, and a flexible tube is provided on the outside of the cable retraction mechanism. The output end of the micro-inhalation device is connected to a multi-layer filter cartridge chamber, and the outside of the multi-layer filter cartridge chamber is fixedly connected to the placement shell.

[0011] As an optional solution for a negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology, as described in this invention, a one-way valve is installed on the outside of the trachea.

[0012] As an optional solution for the negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology as described in this invention, the cable feeding and receiving mechanism includes a support, a cable reel, and a gear disk. The bottom of the support is fixedly connected to the housing. The cable reel is rotatably connected to the outside of the support. A gear disk is fixedly connected to one side of the cable reel. A flexible tube is connected to and wound around the outside of the cable reel. An adjusting disk is engaged with the outside of the gear disk. A rotating shaft is rotatably connected to the center of the adjusting disk. Both ends of the rotating shaft are fixedly connected to the housing.

[0013] As an optional solution for the negative pressure anti-pollution syringe storage box adapted for chemotherapy drug preparation in oncology as described in this invention, a miniature exhaust device is also installed on one side of the inner shell, the output end of the miniature exhaust device is connected to a connecting pipe, the other end of the connecting pipe is connected to an adaptive limiting component, and a solenoid valve is installed on the outside of the connecting pipe.

[0014] During transport, the volume of the medication contained in each syringe varies, and the extension length of the plunger differs, making it difficult to maintain stable positioning using conventional methods. Furthermore, the bumps and vibrations of the transport trolley can cause relative misalignment between the plunger and the syringe body, leading to medication leakage. This device is equipped with an adaptive limiting component. During transport, a miniature exhaust device inflates a flexible positioning airbag via a connecting tube. Once inflated, the airbag tightly adheres to the syringe plunger, achieving adaptive locking and limiting of the plunger, effectively preventing medication leakage caused by transport vibrations.

[0015] Compared with the prior art, the beneficial effects of the present invention are: During the medication preparation stage, the syringe adsorption module is assembled onto the outer wall of the syringe. When the needle punctures the vial, the pressure change inside the vial can easily cause a small amount of medication to splash. At this moment, the gas purification module activates simultaneously, continuously drawing in the splashed medication through the suction port on the side wall of the adsorption sleeve under negative pressure. The medication is then promptly drawn in through a flexible tube and sent to the multi-layer filter chamber for purification via a miniature suction device. During the transport stage, the sealed space of the syringe storage box can easily accumulate toxic volatile gases. The miniature suction device continuously extracts and removes these gases, reducing the concentration of toxins within the sealed cavity and preventing occupational injuries to medical personnel.

[0016] During transport, the volume of the medication contained in each syringe varies, and the extension length of the plunger differs, making it difficult to maintain stable positioning using conventional methods. Furthermore, the bumps and vibrations of the transport trolley can cause relative misalignment between the plunger and the syringe body, leading to medication leakage. This device is equipped with an adaptive limiting component. During transport, a miniature exhaust device inflates a flexible positioning airbag via a connecting tube. Once inflated, the airbag tightly adheres to the syringe plunger, achieving adaptive locking and limiting of the plunger, effectively preventing medication leakage caused by transport vibrations. Attached Figure Description

[0017] Figure 1 A schematic diagram of the overall structure of a negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology. Figure 2 A cross-sectional view of a negative pressure anti-contamination syringe storage box gas purification module adapted for chemotherapy drug preparation in oncology. Figure 3 A schematic diagram of the structure of a negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology. Figure 4 This is a negative pressure, anti-contamination syringe storage box suitable for preparing chemotherapy drugs in oncology departments. Figure 3 A schematic diagram of the structure at point A; Figure 5 A schematic diagram of a negative pressure anti-contamination syringe storage box and syringe adsorption module adapted for chemotherapy drug preparation in oncology. Figure 6 This is a structural diagram of an adaptive limiting component for a negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology.

[0018] In the diagram: 1-syringe storage box, 2-sealed cover, 3-gas purification module, 301-placement shell, 302-miniature suction device, 303-air tube, 304-bracket, 305-reel reel, 306-gear disc, 307-adjusting disc, 308-rotating shaft, 309-one-way valve, 310-multi-layer filter compartment, 311-miniature exhaust device, 312-connecting tube, 313-solenoid valve, 314-branch tube, 4-syringe, 5-sealed cover, 6-syringe adsorption module, 601-adsorption sleeve, 602-suction hole, 603-tight tube, 604-notch, 605-dating sleeve, 7-adaptive limiting component, 701-limiting plate, 702-flexible positioning airbag, 703-connecting air tube, 704-limiting groove, 8-positioning block, 9-dating column. Detailed Implementation

[0019] Example 1: Please refer to Figure 1 , Figure 3 , Figure 4 , Figure 5 and Figure 6 The present invention provides a technical solution: A negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology includes a syringe storage box 1, a sealing cover 2, and a gas purification module 3. A sealing cover 2 is installed on the top of the syringe storage box 1, and an adaptive limiting component 7 is installed inside the sealing cover 2; The syringe storage box 1 is also equipped with a gas purification module 3. The gas purification module 3 is equipped with multiple positioning blocks 8. Each positioning block 8 is equipped with a syringe 4. Each syringe 4 has a sealing cap 5 on one side. The syringe 4 is also equipped with a syringe adsorption module 6 on the outside. The syringe adsorption module 6 includes an adsorption sleeve 601, an air intake hole 602 and a hose 603. The bottom of the adsorption sleeve 601 is provided with a notch 604, and the side of the adsorption sleeve 601 is provided with evenly distributed air intake holes 602. The side of the adsorption sleeve 601 is connected to the hose 603, and the other end of the hose 603 is fixedly connected to the gas purification module 3. The inner side of the adsorption sleeve 601 is fixedly connected to the docking sleeve 605, and the bottom of the docking sleeve 605 is installed with the docking post 9. The bottom of the docking post 9 is fixedly connected to the syringe 4.

[0020] The adsorption sleeve 601 is made of medical flexible rubber sheet.

[0021] The adaptive limiting component 7 includes a limiting plate 701, a flexible positioning airbag 702, and a connecting air tube 703. The outer side of the limiting plate 701 is fixedly connected to the sealing cover 2. A uniformly distributed limiting groove 704 is provided on one side of the limiting plate 701. The flexible positioning airbag 702 is installed inside the limiting plate 701. A connecting air tube 703 is connected to one side of the flexible positioning airbag 702. The other end of the connecting air tube 703 is connected to the gas purification module 3.

[0022] When oncology medical staff prepare chemotherapy drugs, two key operational steps can easily lead to cytotoxic drug residues, posing a potential occupational exposure hazard. First, during the needle puncture of the vial, the rapid pressure fluctuations inside the vial generate numerous microscopic droplets of medication invisible to the naked eye. These droplets easily adhere to the outer conical surface of the syringe's Luer connector, forming nanogram-level cytotoxic drug residues. Second, during drug transport, conventional sealed storage boxes often lack sufficient permeability, preventing the escape of toxic gases volatilized from multiple syringes, causing a continuous accumulation of toxic gas concentrations within the box. While there is no immediate risk of drug leakage and contamination in this scenario, subsequent operations such as transport, opening the vial for use, and drug verification can easily lead to concentrated occupational exposure. This device addresses this by assembling the syringe adsorption module 6 onto the outer wall of the syringe 4 during the drug preparation phase. When the needle punctures the vial, the pressure change inside the vial can easily cause a small amount of medication to splash out. At this moment, the gas purification module 3 is activated simultaneously. The suction port 602 on the side wall of the adsorption sleeve 601 continuously draws in the splashed medication through the tubing 603, and then through the micro-suction device 302 to the multi-layer filter chamber 310 for purification. During the transport stage, the sealed space of the syringe storage box 1 is prone to accumulating toxic volatile gases. Relying on the micro-suction device 302 to continuously draw out the gases, the concentration of toxic substances in the sealed cover 2 cavity is reduced, thus avoiding occupational injuries to medical personnel.

[0023] Also includes the following: During the drug preparation process, the inner connecting sleeve 605 of the adsorption sleeve 601 is assembled onto the outside of the connecting column 9. The adsorption sleeve 601 is made of flexible material and has deformation capability, making it easy for the adsorption sleeve 601 to be fitted onto the outer wall of the syringe 4 through the bottom notch 604. The suction port 602 on the side of the adsorption sleeve 601 is aligned with the Luer interface of the syringe 4, and the gas purification module 3 is turned on. During the use of the equipment, the toxic medium that leaks out instantly when the needle punctures the vial can be drawn into the multi-layer filter chamber 310 of the gas purification module 3 through the suction port 602 for purification. The purified gas flows back into the syringe storage box 1, realizing continuous air circulation and purification inside the box. The gas circulates in a closed loop inside the box, preventing pollution from the external environment.

[0024] After the medication preparation is completed, the syringe 4 can be placed directly on the top surface of the positioning block 8, and the cover 2 can be rotated to close the box. At this time, the gas purification module 3 is activated to fill the flexible positioning airbag 702 with gas; the limiting groove 704 of the limiting plate 701 is adapted to engage with the outer wall of the syringe 4, and the flexible positioning airbag 702 can adaptively clamp and limit according to the actual position of the syringe 4 push handle, preventing leakage of the medicine caused by bumps during transportation, and at the same time avoiding the harm to the health of medical staff caused by the waste gas remaining in the box during the use of the medicine.

[0025] Positioning block 8 can be disassembled and removed as a whole, making it convenient to carry out disinfection operations.

[0026] Example 2: This example is an improvement upon Example 1. Please refer to [link / reference]. Figure 2 Specifically, the gas purification module 3 includes a housing 301, a micro-inhalation device 302, and air pipes 303. A groove is provided on the top of the housing 301, and multiple positioning blocks 8 are provided in the groove. The micro-inhalation device 302 is installed inside the housing 301. The input end of the micro-inhalation device 302 is connected to a branch pipe 314. The other end of the branch pipe 314 is connected to evenly distributed air pipes 303. The other end of each air pipe 303 is connected to a cable winding mechanism. The cable winding mechanism is fixedly connected to the housing 301 on the outside. A flexible hose 603 is provided on the outside of the cable winding mechanism. The output end of the micro-inhalation device 302 is connected to a multi-layer filter chamber 310. The outer side of the multi-layer filter chamber 310 is fixedly connected to the housing 301.

[0027] One-way valves 309 are installed on the outside of the trachea 303.

[0028] The take-up and take-down mechanism includes a bracket 304, a take-up reel 305, and a gear disk 306. The bottom of the bracket 304 is fixedly connected to the housing 301. The take-up reel 305 is rotatably connected to the outside of the bracket 304. The gear disk 306 is fixedly connected to one side of the take-up reel 305. The outside of the take-up reel 305 is connected to and wound with a flexible hose 603. An adjusting disc 307 is engaged on the outside of the gear disk 306. A rotating shaft 308 is rotatably connected to the center of the adjusting disc 307. Both ends of the rotating shaft 308 are fixedly connected to the housing 301.

[0029] A miniature exhaust device 311 is also installed on one side of the inner side of the housing 301. The output end of the miniature exhaust device 311 is connected to a connecting pipe 312. The other end of the connecting pipe 312 is connected to the adaptive limit member 7. A solenoid valve 313 is installed on the outside of the connecting pipe 312.

[0030] During transport, the volume of the medication contained in each syringe 4 varies, and the extension length of the plunger differs, making it difficult to maintain stable positioning using conventional methods. The bumps and vibrations of the transport trolley can easily cause relative misalignment between the plunger and the syringe body, leading to medication leakage. This device is equipped with an adaptive limiting component 7. During transport, a miniature exhaust device 311 inflates a flexible positioning airbag 702 via a connecting pipe 312. After the airbag expands, it tightly fits against the plunger of the syringe 4, achieving adaptive locking and limiting of the plunger, effectively preventing medication leakage caused by transport shaking.

[0031] Also includes the following: When syringe 4 is removed, it moves the tubing 603 accordingly. This movement of tubing 603 causes the take-up reel 305 to automatically release it. One end of tubing 603 connects to the air tube 303 through the hollow interior of the take-up reel 305. This allows for targeted suction at the Luer interface of syringe 4. After suction is complete, manually rotating the exposed adjustment disc 307 on one side rotates the gear 306, which in turn reverses the take-up reel 305, facilitating the retraction of tubing 603. The tubing 603 passes through the positioning block 8. When not in use, the one-way valve 309 on the outside of the tubing 303 ensures that air can only flow in one direction, preventing toxic gas from flowing back and causing repeated contamination. The cable retraction mechanism is arranged in multiple groups side by side, which facilitates targeted adsorption treatment of syringes 4 in different positions. The adsorbed toxic gas is discharged into the multi-layer filter chamber 310, where the toxic gas can be treated in a targeted manner to avoid harm to medical staff. The treated clean air can flow back into the box to achieve circulating gas treatment. When inflating the adaptive limiter 7, the external air can smoothly enter the interior of the adaptive limiter 7 through the connecting pipe 312 by activating the micro exhaust device 311. After limiting the push handle, the solenoid valve 313 can be closed. When opening the box, the solenoid valve 313 is opened to perform a pre-venting operation to avoid the adaptive limiter 7 from affecting the push handle.

[0032] This article uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only for the purpose of helping to understand the method and core ideas of the present invention. The above descriptions are only preferred embodiments of the present invention. It should be noted that due to the limitations of textual expression, while there are objectively infinite specific structures, those skilled in the art can make several improvements, modifications, or changes without departing from the principles of the present invention, and can also combine the above technical features in an appropriate manner. These improvements, modifications, changes, or combinations, or the direct application of the inventive concept and technical solution to other situations without modification, should all be considered within the scope of protection of the present invention.

Claims

1. A negative pressure, anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology departments, characterized in that: It includes a syringe storage box (1), a sealing cap (2), and a gas purification module (3); A sealing cover (2) is installed on the top of the syringe storage box (1), and an adaptive limiting component (7) is installed inside the sealing cover (2). The syringe storage box (1) is also equipped with a gas purification module (3), and the gas purification module (3) is equipped with multiple positioning blocks (8). Each positioning block (8) is equipped with a syringe (4). Each syringe (4) has a sealing cap (5) on one side. The syringe (4) is also equipped with a syringe adsorption module (6) on the outside. The syringe adsorption module (6) includes an adsorption sleeve (601), an air inlet (602) and a hose (603). The bottom of the adsorption sleeve (601) is provided with a notch (604), and a uniformly distributed air inlet (602) is provided on one side of the adsorption sleeve (601). The side of the adsorption sleeve (601) is connected to the hose (603), and the other end of the hose (603) is fixedly connected to the gas purification module (3). The inner side of the adsorption sleeve (601) is fixedly connected to the docking sleeve (605), and the bottom of the docking sleeve (605) is installed with the docking post (9). The bottom of the docking post (9) is fixedly connected to the syringe (4).

2. The negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology departments according to claim 1, characterized in that: The adsorption sleeve (601) is made of medical flexible rubber sheet.

3. The negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology departments according to claim 1, characterized in that: The adaptive limiting component (7) includes a limiting plate (701), a flexible positioning airbag (702), and a connecting air tube (703). The outer side of the limiting plate (701) is fixedly connected to the sealing cover (2). A uniformly distributed limiting groove (704) is provided on one side of the limiting plate (701). The flexible positioning airbag (702) is installed inside the limiting plate (701). A connecting air tube (703) is connected to one side of the flexible positioning airbag (702). The other end of the connecting air tube (703) is connected to the gas purification module (3).

4. The negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology departments according to claim 1, characterized in that: The gas purification module (3) includes a housing (301), a micro air intake device (302), and an air tube (303). A groove is provided on the top of the housing (301), and multiple positioning blocks (8) are provided in the groove. The micro air intake device (302) is installed inside the housing (301). The input end of the micro air intake device (302) is connected to a branch pipe (314). The other end of the branch pipe (314) is connected to a uniformly distributed air tube (303). The other end of the air tube (303) is connected to a wire take-up and release mechanism. The outer side of the wire take-up and release mechanism is fixedly connected to the housing (301). A flexible hose (603) is provided on the outer side of the wire take-up and release mechanism. The output end of the micro air intake device (302) is connected to a multi-layer filter chamber (310). The outer side of the multi-layer filter chamber (310) is fixedly connected to the housing (301).

5. A negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology departments according to claim 4, characterized in that: One-way valves (309) are installed on the outside of the trachea (303).

6. A negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology departments according to claim 4, characterized in that: The take-up and take-down mechanism includes a bracket (304), a take-up reel (305), and a gear disc (306). The bottom of the bracket (304) is fixedly connected to the housing (301). The take-up reel (305) is rotatably connected to the outside of the bracket (304). The gear disc (306) is fixedly connected to one side of the take-up reel (305). The outside of the take-up reel (305) is connected to and wound with a flexible hose (603). The outside of the gear disc (306) is engaged with an adjusting disc (307). The center of the adjusting disc (307) is rotatably connected to a rotating shaft (308). The two ends of the rotating shaft (308) are fixedly connected to the housing (301).

7. A negative pressure anti-contamination syringe storage box adapted for chemotherapy drug preparation in oncology departments according to claim 4, characterized in that: A miniature exhaust device (311) is also installed on one side of the inner side of the housing (301). The output end of the miniature exhaust device (311) is connected to a connecting pipe (312). The other end of the connecting pipe (312) is connected to an adaptive limiter (7). A solenoid valve (313) is installed on the outside of the connecting pipe (312).