A reagent anti-volatilization sealing device for a biological detection station

Abstract

This invention relates to the field of biological reagent storage technology, specifically a reagent anti-volatility sealing device for a biological testing station. It includes a sealed chamber, a volatile detection device positioned above the sealed chamber, and a volatile reagent placement chamber separated from the sealed chamber by a base plate. The sealed chamber has a sealed access channel with a door on one side, and the volatile reagent placement chamber has sealed doors at both the front and rear. A dropping mechanism is provided between the sealed chamber and the volatile reagent placement chamber. This invention independently seals each reagent tube, and without affecting the reagent's resting state, cyclically tests each reagent for leakage and volatile emissions. From the moment the reagent is placed until the staff touches it again, the entire process is sealed. When the staff touches the reagent again, it is automatically sorted into three categories, awaiting separate processing.

Description

Technical Field

[0001] This invention relates to the field of biological testing reagent storage technology, specifically a reagent anti-volatilization sealing device for biological testing workstations. Background Technology

[0002] Biological testing involves the use of numerous reagents. While reagents must be sealed during storage, simply sealing them with caps or plugs does not eliminate the risk of evaporation. The volatilization of chemical reagents can cause various hazards, including air pollution, the formation of secondary pollutants, harm to human health, fire and explosion risks, and water and soil contamination. Workers who handle these reagents are particularly vulnerable and suffer the most direct and severe harm.

[0003] Currently, the solution to the problem of reagent volatilization is to use a vacuum filtration system. This involves drawing out toxic and harmful gases emitted from the sealed storage unit using negative pressure, followed by filtration and release. However, staff ultimately still need to open the sealed door of the storage unit to retrieve the reagents, and sometimes even continue using them after unaware of the volatilization. The toxic and harmful substances emitted by the reagents continue to come into contact with staff and are inhaled by everyone entering the room. Furthermore, the volatilization process varies for each reagent, and the current negative pressure vacuum system cannot classify and handle volatilization according to the specific volatilization characteristics of each reagent, failing to ensure that volatilized reagents are sealed and rendered harmless. Summary of the Invention

[0004] The purpose of this invention is to provide a reagent anti-volatility sealing device for biological testing stations, so as to solve the problems that the existing negative pressure suction method for preventing reagent volatilization cannot prevent the volatiles from coming into contact with the human body and air, and cannot perform graded treatment according to the specific volatilization of the reagent.

[0005] To achieve the above objectives, the present invention provides the following technical solution: A reagent anti-volatile sealing device for a biological detection station includes a sealed chamber, a volatile detection device disposed above the sealed chamber, and a volatile reagent placement chamber disposed below the sealed chamber and separated by a base plate. The sealed chamber has a sealed access channel with a door on one side, and the volatile reagent placement chamber has sealed doors at both the front and rear. A falling mechanism is provided in the sealed chamber and the volatile reagent placement chamber. The falling mechanism includes a sealing sleeve fixing plate, a rotating plate, a pushing mechanism, an upper through hole, and a falling hole. The sealing sleeve fixing plate is located in the sealed chamber and has an upper through hole. The rotating plate is attached to the bottom plate and has a falling hole. The upper through hole and the falling hole are offset. The pushing mechanism is located below the rotating plate and its blades are close to the rear of the falling hole. A motor is fixedly installed on the top of the sealing chamber. The motor's shaft is fixedly connected to the sealing sleeve fixing plate, the rotating plate, and the pushing mechanism, driving the three components to rotate synchronously. The sealing sleeve fixing plate is fixedly installed at the upper perforation, and the sealing sleeve can be detached independently. The sealing sleeve is formed by connecting the lower sealing half and the upper sealing half, and is used to accommodate the reagent tube. Below the volatile detection device is a pushing mechanism for pressing down the sealing sleeve and forming an airflow channel. The air inlet of the volatile detection device is connected to the air pipe of the pushing mechanism for detecting the concentration of volatiles inside the sealing sleeve. The volatile detection device includes a gas sensor module, a signal processing circuit, a control unit, and a miniature air pump. The control unit is electrically connected to the motor and the cylinder of the pushing mechanism, and is used to control the start and stop of the motor, the speed, and the extension stroke of the cylinder.

[0006] As a further description of the above technical solution: The lower sealing half-set includes a lower tube, an annular slot, a primary annular sealing ring, and a secondary annular sealing ring. The inner side wall of the lower tube is provided with an annular slot, and the primary annular sealing ring and the secondary annular sealing ring are arranged sequentially from top to bottom in the annular slot. The upper sealing half-set includes an upper tube, and the lower part of the upper tube is provided with an annular snap ring that can be inserted into an annular slot to seal with the primary annular sealing ring and the secondary annular sealing ring.

[0007] As a further description of the above technical solution: The upper part of the upper tube is provided with a retractable corrugated section.

[0008] As a further description of the above technical solution: The top of the upper tube is provided with an outer body, and the inside of the outer body is provided with an inner tube. The top of the upper tube is provided with a convex tube on the inner side of the outer body. A movable sealing cap is provided between the inner tube and the convex tube. The movable sealing cap can cover the convex tube. There is a gap between the side of the movable sealing cap and the inner wall of the outer body. A spring is sleeved on the convex tube. The spring always pushes the movable sealing cap upward to block the lower opening of the inner tube.

[0009] As a further description of the above technical solution: The pushing mechanism includes a vent pipe, a lower pressure plate, a cylinder, a connector, a pressure pipe, a corrugated sealing pipe, a sealing ring, and a push rod; The cylinder is fixedly installed below the volatile detection device, and its piston rod is fixedly connected to the lower pressure plate. One end of the vent pipe is connected to the air inlet of the volatile detection device, and the other end is connected to the pressure pipe. The pressure pipe is integrally connected to the corrugated sealing pipe. The lower end of the corrugated sealing pipe is provided with a sealing ring plate, which can be pressed against the top of the extension body to form a sealing channel. A push rod is fixedly installed at the center of the connector. The push rod extends into the inner tube to press down the movable sealing cover, causing it to separate from the inner tube and form an airflow channel.

[0010] As a further description of the above technical solution: The lower outer side of the upper tube is provided with two sealing marking lines. The upper sealing marking line corresponds to the secondary annular sealing ring, and the lower sealing marking line corresponds to the primary annular sealing ring.

[0011] As a further description of the above technical solution: The inner surfaces of the lower and upper tubes are provided with a buffer layer, and the bottom of the lower tube is provided with a guide arc surface.

[0012] As a further description of the above technical solution: The sealing sleeve fixing plate is provided with an upper fixing ring at the upper perforation position, and the top of the upper sealing half sleeve is fixed with a lower fixing ring outside the extension body. The lower fixing ring and the upper fixing ring can be detachably connected by adhesive or magnetic adsorption.

[0013] As a further description of the above technical solution: The control unit of the volatile detection device is equipped with low-risk concentration thresholds and high-risk concentration thresholds. The control unit controls the extension stroke of the cylinder based on the detection results. When the detected concentration is below the low-risk concentration threshold, the cylinder extends and immediately retracts to reset, and the annular snap ring is positioned above the initial annular seal ring, with both seal marking lines visible. When the detected concentration reaches the low-risk concentration threshold, the cylinder continues to increase the first stroke, causing the annular snap ring to pass over the initial annular sealing ring and enter a hook-and-seal state, with only the sealing mark line at the top visible. When the detected concentration reaches or exceeds the high-risk threshold, the cylinder continues to increase the second stroke, causing the annular snap ring to pass over the secondary annular sealing ring and enter a hook-and-seal state, with both sealing marking lines hidden.

[0014] As a further description of the above technical solution: The motor, cylinder, solenoid valve, and volatile detection device are all installed outside the sealed chamber. The shells of the sealed chamber and the volatile reagent placement chamber are made of antistatic material and are equipped with grounding terminals.

[0015] Compared with the prior art, the present invention provides a reagent anti-volatility sealing device for a biological detection station, which has the following beneficial effects: 1. This invention abandons the existing method of exposing reagents and then using negative pressure ventilation to remove volatiles. Instead, it adopts an independent, sealed placement of each reagent tube. Without affecting the reagent's settling time, each reagent is individually tested for leakage and evaporation. The evaporation detection uses a dynamic sealing method: downward pressure creates an airflow channel, and upward pressure disconnects the airflow channel. The evaporation detection results are handled in three ways: the tubes continue to stand for the next test; low-risk concentrations are tightly sealed once; high-risk concentrations are tightly sealed a second time; tubes that continue to stand are not tightly sealed for easy access to the reagent; tubes are tightly sealed once, allowing staff to choose whether to open the seal and retrieve the entire reagent; and tubes that are sealed a second time undergo harmless treatment along with the outer sealing sleeve. Throughout the entire process, from the moment the reagent is placed until the staff touches it again, the entire process is sealed. When the staff touches the reagent again, it is automatically sorted into three categories for separate processing.

[0016] 2. In this invention, all electrically powered mechanisms are externally located to prevent internal electrical components from coming into contact with volatile substances and causing danger. The overall sealing degree of the reagent-containing sealing sleeve is visible, the body can be adjusted and extended according to the length of the reagent tube, and it has a built-in buffer layer to prevent damage when the reagent tube moves.

[0017] 3. This invention adopts a misalignment method, with the upper perforation and the lower drop hole misaligned. The blades of the pushing mechanism are positioned near the rear of the lower drop hole. The sealing sleeve fixing plate, the rotating plate, and the pushing mechanism are all fixedly mounted on the motor shaft. The rotation of one shaft simultaneously realizes reagent volatilization detection, the sealing sleeve falling off and standing upright, the sealing sleeve falling down, and the sealing sleeve being pushed open. The invention achieves the desired reagent volatilization detection purpose with the simplest possible structural design. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the fixing structure of the upper fixing ring and the lower fixing ring of the present invention; Figure 2 This is a schematic diagram of the structure of the extension body extending out of the sealing sleeve fixing plate of the present invention; Figure 3 This is a schematic diagram of the perforation location structure of the present invention; Figure 4 This is a schematic diagram of the cross-sectional structure of the lower sealing half-sleeve and the upper sealing half-sleeve of the present invention. Figure 5 For the present invention Figure 4 A magnified structural diagram of A in the middle; Figure 6 For the present invention Figure 4 A magnified structural diagram of B in the diagram; Figure 7 This is a schematic cross-sectional view of the pushing mechanism of the present invention; Figure 8 This is a schematic diagram of the sealing mark line position structure of the present invention; Figure 9 This is a schematic diagram of the rotating plate position structure of the present invention; Figure 10 This is a schematic diagram of the external structure of the detection state of the present invention; Figure 11 This is a schematic diagram of the external structure for detecting the state of the present invention.

[0019] Legend: 1. Sealed chamber; 101. Sealed access channel; 2. Volatile reagent storage chamber; 3. Sealed door; 4. Motor; 5. Volatile detection device; 6. Base plate; 7. Lower perforation; 8. Falling mechanism; 801. Sealing sleeve fixing plate; 802. Rotating plate; 803. Pushing mechanism; 804. Upper perforation; 805. Falling hole; 9. Lower sealing half-sleeve; 901. Lower tube; 902. Annular slot; 903. Primary annular sealing ring; 904. Secondary annular sealing ring; 905. Guide arc surface; 10. Upper sealing half-sleeve; 1001 1002. Upper tube; 1003. Corrugated section; 1004. Outer body; 1005. Inner tube; 1006. Convex tube; 1007. Movable sealing cap; 1008. Spring; 1009. Lower fixing ring; 1010. Annular snap ring; 1011. Sealing mark line; 11. Pushing mechanism; 1101. Vent pipe; 1102. Lower pressure plate; 1103. Cylinder; 1104. Connector; 1105. Pressure pipe; 1106. Corrugated sealing pipe; 1107. Sealing ring; 1108. Push rod; 12. Upper fixing ring. Detailed Implementation

[0020] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0021] Example 1: Please see Figures 1-11This invention provides a reagent anti-volatile sealing device for a biological detection station, including a sealed chamber 1, a volatile detection device 5 disposed above the sealed chamber 1, and a volatile reagent placement chamber 2 separated from the sealed chamber 1 by a base plate 6. The sealed chamber 1 has a door-equipped access channel 101 on one side, and the volatile reagent placement chamber 2 has sealing doors 3 at both the front and rear. A falling mechanism 8 is provided inside both the sealed chamber 1 and the volatile reagent placement chamber 2. The falling mechanism 8 includes a sealing sleeve fixing plate 801, a rotating plate 802, a pushing mechanism 803, an upper through hole 804, and a falling hole 805. The sealing sleeve fixing plate 801 is located in the sealed chamber 1 and has the upper through hole 804. The rotating plate 802 is attached to the bottom of the base plate 6 and has the falling hole 805. The upper surface of the rotating plate 802 is in contact with the lower surface of the base plate 6. The lower perforation 7 is directly below the rotating plate 802. When the sealing sleeve falls, its bottom passes through the lower perforation 7 and lands on the upper surface of the rotating plate 802. When the lower hole 805 rotates to be directly below the lower perforation 7, the sealing sleeve falls into the bottom of the volatile reagent placement chamber 2. The upper perforation 804 and the lower hole 805 are staggered. The pushing mechanism 803 is located below the rotating plate 802 and its blades are close to the rear of the lower hole 805. The blades of the pushing mechanism 803 are located below the rotating plate 802. After the sealing sleeve falls from the lower perforation 7, it lands at the bottom of the volatile reagent placement chamber 2. When the motor 4 rotates, the blades push the sealing sleeve to one side along the rotation direction to prevent accumulation and blockage of the lower perforation 7. A motor 4 is fixedly installed on the top of the sealing chamber 1. The rotating shaft of the motor 4 is fixedly connected to the sealing sleeve fixing plate 801, the rotating plate 802 and the pushing mechanism 803, driving the three components to rotate synchronously. The sealing sleeve fixing plate 801 is fixedly installed at the upper through hole 804. The sealing sleeve is formed by connecting the lower sealing half sleeve 9 and the upper sealing half sleeve 10, and is used to accommodate the reagent tube. A pushing mechanism 11 is provided below the volatile detection device 5 to press down the sealing sleeve and form an airflow channel. The air inlet of the volatile detection device 5 is connected to the air pipe 1101 of the pushing mechanism 11 to detect the concentration of volatiles inside the sealing sleeve. The volatile detection device 5 includes a gas sensor module, a signal processing circuit, a control unit, and a micro air pump. The control unit is electrically connected to the motor 4 and the cylinder 1103 of the pushing mechanism 11, and is used to control the start and stop of the motor 4, the speed, and the extension stroke of the cylinder 1103.

[0022] Specifically, such as Figure 6 As shown, the lower sealing half-set 9 includes a lower tube 901, an annular slot 902, a primary annular sealing ring 903 and a secondary annular sealing ring 904. The inner side wall of the lower tube 901 is provided with an annular slot 902, and the primary annular sealing ring 903 and the secondary annular sealing ring 904 are arranged sequentially from top to bottom in the annular slot 902. The upper sealing half-set 10 includes an upper tube 1001. The lower part of the upper tube 1001 is provided with an annular snap ring 1009 that can be inserted into the annular slot 902 to seal with the primary annular sealing ring 903 and the secondary annular sealing ring 904. When the upper tube 1001 and the lower tube 901 are connected, the annular snap ring 1009 plays the role of increasing the firmness of the connection.

[0023] Specifically, such as Figures 4-5 As shown, the upper part of the upper tube 1001 is provided with a retractable corrugated section 1002. When the sealing sleeve cannot be opened, the corrugated section 1002 can be stretched to break it open without damaging the reagent tube. Specifically, such as Figure 5 As shown, the top of the upper tube 1001 is provided with an extension body 1003, and the interior of the extension body 1003 is provided with an inner tube 1004. The top of the upper tube 1001, located inside the extension body 1003, is provided with a protruding tube 1005. A movable sealing cover 1006 is provided between the inner tube 1004 and the protruding tube 1005. The movable sealing cover 1006 can cover the protruding tube 1005. A gap is left between the side of the movable sealing cover 1006 and the inner wall of the extension body 1003. A spring 1007 is sleeved on the protruding tube 1005. 07. The movable sealing cap 1006 is always pushed upward to block the lower opening of the inner tube 1004. During the process of the pushing mechanism 11 separating from the sealing sleeve, the airflow channel at the top of the sealing sleeve is sealed to prevent the leakage of toxic and harmful gases emitted by the reagent. The side wall of the extension body 1003 may be provided with tiny air replenishment holes with a diameter ≤0.1mm, or the air pressure can be naturally balanced by the gap between the movable sealing cap 1006 and the inner tube 1004 to ensure that the movable sealing cap 1006 is reliably reset under the action of the spring 1007.

[0024] Specifically, such as Figure 7 As shown, the pushing mechanism 11 includes a vent pipe 1101, a lower pressure plate 1102, a cylinder 1103, a connector 1104, a pressure pipe 1105, a corrugated sealing pipe 1106, a sealing ring 1107, and a push rod 1108. The cylinder 1103 is fixedly installed below the volatile detection device 5. Its piston rod is fixedly connected to the lower pressure plate 1102. One end of the air pipe 1101 is connected to the air inlet of the volatile detection device 5, and the other end is connected to the pressure pipe 1105. The pressure pipe 1105 is integrally connected to the corrugated sealing pipe 1106. The lower end of the corrugated sealing pipe 1106 is provided with a sealing ring 1107. The sealing ring 1107 can be pressed against the top of the extension body 1003 to form a sealing channel. A push rod 1108 is fixedly installed at the center of the connector 1104. The push rod 1108 extends into the inner tube 1004 to press down the movable sealing cover 1006 to separate it from the inner tube 1004 and form an airflow channel. The extension and retraction of cylinder 1103 enables the switching between the sealing channel and the airflow channel of the sealing sleeve, thus simultaneously meeting the requirements of both sealing detection and sealing against volatilization. The base plate 6 is provided with a lower through hole 7 coaxial with the push rod 1108 for the sealing sleeve to fall.

[0025] Specifically, such as Figure 8 As shown, the lower outer side of the upper tube 1001 is provided with two sealing mark lines 1010. The upper sealing mark line 1010 corresponds to the secondary annular sealing ring 904, and the lower sealing mark line 1010 corresponds to the primary annular sealing ring 903. The upper tube 1001 is moved down, and the setting of the sealing mark lines 1010 makes the evaporation of each test tube more intuitive without increasing the cost of intelligentization or the burden of careful visual identification.

[0026] Specifically, such as Figures 4-6 As shown, the inner surfaces of the lower tube 901 and the upper tube 1001 are provided with buffer layers, and the bottom of the lower tube 901 is provided with a guide arc surface 905. The buffer layers are located at three positions: the side wall, the top, and the bottom. The buffer layers on the side wall are spaced apart or one is provided on each of the lower tube 901 and the upper tube 1001. The bottom buffer layer is provided on the lower tube 901, and the top buffer layer is provided on the upper tube 1001. The guide arc surface 905 allows the upper tube 1001 to be inserted into the annular slot 902 more smoothly.

[0027] Specifically, such as Figure 2 As shown, the sealing sleeve fixing plate 801 has an upper fixing ring 12 at the upper through hole 804. The top of the upper sealing half sleeve 10 is fixed with a lower fixing ring 1008 outside the extension body 1003. The lower fixing ring 1008 and the upper fixing ring 12 can be detachably connected by adhesive or magnetic adsorption. Fixing the sealing sleeve by adhesive or magnetic adsorption is both firm and easy to remove. For sealing sleeves that do not volatilize, they can be reused, reducing costs.

[0028] Specifically, the control unit of the volatile detection device 5 is equipped with low-risk concentration thresholds and high-risk concentration thresholds. The control unit controls the extension stroke of the cylinder 1103 according to the detection results. When the detected concentration is below the low-risk concentration threshold, the cylinder 1103 extends and immediately retracts to reset, the annular snap ring 1009 is positioned above the initial annular sealing ring 903, and both sealing marking lines 1010 are visible. When the detected concentration reaches the low-risk concentration threshold, the cylinder 1103 continues to increase the first stroke, so that the annular snap ring 1009 crosses the initial annular sealing ring 903 and is in a hook-and-seal state, with only the sealing mark line 1010 at the top visible. When the detected concentration reaches or exceeds the high-risk threshold, the cylinder 1103 continues to increase the second stroke, causing the annular snap ring 1009 to pass over the secondary annular sealing ring 904 and enter a hook-and-seal state, and both sealing marking lines 1010 are hidden. The reagents are automatically sorted into three categories, awaiting separate processing.

[0029] Specifically, such as Figure 9-11 As shown, the motor 4, cylinder 1103 and its solenoid valve, and the volatile detection device 5 are all installed outside the sealed chamber 1. The shells of the sealed chamber 1 and the volatile reagent placement chamber 2 are made of antistatic material and are equipped with grounding terminals to prevent the built-in electrical components from coming into contact with volatiles and causing danger.

[0030] Working principle: Open the door of 101, pull the empty lower sealing half 9 and upper sealing half 10 together to form a sealing sleeve and remove it to position 101. Insert the lower part of the reagent tube with the sealing cap on into the lower tube 901, and then insert the upper part of the reagent tube into the upper tube 1001. Insert the bottom of the upper tube 1001 into the annular slot 902 and the annular buckle ring 1009 is located above the initial annular sealing ring 903. The lower sealing half-sleeve 9 and the upper sealing half-sleeve 10 are preferably made of transparent polymer materials, such as transparent polypropylene; The initial annular sealing ring 903 serves as a downward limiting element for the annular snap ring 1009. The upper tube 1001 and the lower tube 901 will not separate due to the frictional resistance of the insertion dock. The lower fixing ring 1008 and the upper fixing ring 12 are then pasted or adsorbed back. The corrugated section 1002 is in a contracted state. The lower fixing ring 1008 is attached or adsorbed to the upper fixing ring 12 on the sealing sleeve fixing plate 801. The sealing sleeve containing the reagent is affected by gravity and hangs down inside the sealing chamber 1. There is a gap between the bottom of the lower tube 901 and the base plate 6. In this way, when the shaft of the motor 4 rotates, the lower tube 901 does not contact the base plate 6, thus avoiding the sealing sleeve from rubbing and tilting when the shaft of the motor 4 rotates. A rotary seal, such as an oil seal or a magnetic fluid seal, is provided between the rotating shaft of the motor 4 and the housing of the sealing chamber 1 to ensure the airtightness of the sealing chamber. An encoder or Hall sensor is installed on the rotating shaft of the motor 4, or a photoelectric sensor is set outside the sealing chamber 1 to detect the rotational position of the sealing sleeve fixing plate 801. The control unit controls the start and stop of the motor 4 according to the sensor signal. When the rotating shaft is working, since the sealing sleeve fixing plate 801, rotating plate 802, pushing mechanism 803 and the sealing sleeve of the built-in reagent tube are all fixedly connected to it, the motor 4 will drive the sealing sleeve fixing plate 801, rotating plate 802, pushing mechanism 803 and the sealing sleeve of the built-in reagent tube to rotate synchronously. Because the upper through hole 804 of the sealing sleeve fixing plate 801 and the lower hole 805 of the rotating plate 802 are staggered, and the pushing mechanism 803 is located near the rear of the lower hole 805, that is, downstream of the rotation direction, the number of blades of the upper through hole 804, the lower hole 805 and the pushing mechanism 803 are consistent, and the thickness of the rotating plate 802 is at least 5cm, so that the sealing sleeve can be limited to stand upright after falling and avoid tipping over; When the entire sealing sleeve of the built-in reagent tube is not under pressure, and the top of the upper sealing half sleeve 10 is not under pressure, the spring 1007 extends and pushes the movable sealing cover 1006 to the bottom of the inner tube 1004. In this way, the movable sealing cover 1006 seals the inner tube 1004, and the entire sealing sleeve will not allow air to enter from the outside, nor will the air inside flow out, and there is no interaction between the internal and external airflow. When the sealing sleeve of the built-in reagent tube rotates to the position of the pushing mechanism 11, the cylinder 1103 extends and lowers the vent pipe 1101. The tube body of the vent pipe 1101 above the lower pressure plate 1102 is a flexible tube, and its length is sufficient for the cylinder 1103 to extend and move. When the cylinder 1103 pushes the lower pressure plate 1102 down, the sealing ring 1107 is sleeved on the outside of the extension body 1003, and the push rod 1108 passes through the inner tube 1004 and presses on the convex tube 1005. The lower the position of the lower pressure plate 1102, the corrugated sealing tube 1106 contracts, and the movable sealing cover 1006 is pushed open and separated from the inner tube 1004. In this way, the inside of the sealing sleeve of the built-in reagent tube and the inner cavity of the corrugated sealing tube 1106 form an airflow channel. The gas inside the sealing sleeve is slowly drawn into the volatilization detection device 5 through the connector 1104 and the vent pipe 1101. After the volatile detection device 5 completes the detection, if no reagent volatiles are detected, the cylinder 1103 contracts, the corrugated sealing tube 1106 slowly extends, and the sealing ring 1107 remains pressed on the top of the outer body 1003 to prevent the gas inside the sealing sleeve from leaking out. At the same time, the push rod 1108 separates from the movable sealing cover 1006, the spring 1007 extends, and the movable sealing cover 1006 is lifted back to its original position to seal the opening of the inner tube 1004. After the sealing ring 1107, the push rod 1108 and the top of the outer body 1003 separate, the airflow channel is disconnected, the gas inside the sealing sleeve does not leak out, and the sealing sleeve remains hanging on the sealing sleeve fixing plate 801. The volatile detection device 5 continues to work and rotates the next reagent to the position of the pushing mechanism 11 for detection. After the volatile detection device 5 completes the detection, if reagent volatiles are detected, the cylinder 1103 continues to extend and apply downward pressure. The movable sealing cover 1006 is pushed down. Because the sealing sleeve cannot withstand the continuous downward pressure, the lower fixing ring 1008 separates from the upper fixing ring 12. After separation, the sealing sleeve falls down. The falling sealing sleeve passes through the lower through hole 7 and stands outside the drop hole 805 of the rotating plate 802. Because it is supported by the rotating plate 802 and limited by the lower through hole 7, the cylinder 1103 can continue to press down. The push rod 1108 pushes down 10, and the upper tube 1001 is pressed deeper and deeper in the annular slot 902 until the annular buckle ring 1009 is squeezed through the primary annular sealing ring 903 or the secondary annular sealing ring 904. At this time, the lower sealing half 9 and the upper sealing half 10 are completely fixed, the docking position is further sealed, the cylinder 1103 retracts, the spring 1007 extends, the movable sealing cover 1006 resets and blocks the lower opening of the inner tube 1004, the sealing sleeve becomes a completely sealed state, and the toxic and harmful substances volatilized in the reagent tube cannot escape from the sealing sleeve. Motor 4 continues to work, and the sealing sleeve fixing plate 801 rotates to slowly rotate the next reagent tube to be tested to the position of the pushing mechanism 11. The sealing sleeve of the previously tested detached reagent tube containing volatile reagent is stuck on the rotating plate 802 because it is stuck at the lower perforation 7. When the rotating shaft of motor 4 rotates the lower hole 805 of the rotating plate 802 to the position of the lower perforation 7, the sealing sleeve automatically falls into the sealing door 3 because the lower perforation 7 and the lower hole 805 are connected. Since the inner side of the lower sealing half 9 and the upper sealing half 10 are provided with a buffer layer, the buffer layer can protect the reagent tube well when the reagent tube moves with the sealing sleeve and avoid damage. After the sealing sleeve falls, the rotating plate 802 continues to rotate. When the pushing mechanism 11 detects whether the next reagent has evaporated, the lower perforation 7 will be sealed by the misalignment of the lower perforation 7 and the lower hole 805, so that the contents of the sealing chamber 1 form a completely sealed cavity. The falling sealing sleeve has two states: first, the sealing sleeve falls and rolls over; second, the sealing sleeve stands upright and does not move. At this time, the synchronously rotating pushing mechanism 803 is still in the position outside the lower perforation 7 because the detection of the pushing mechanism 11 is still in the position. After the next reagent is detected, the evaporation detection device 5 rotates and the pushing mechanism 803 rotates to rotate and push away the sealing sleeves that are located below the lower perforation 7, whether lying down or standing up, so as to avoid affecting the next evaporating reagent from falling. Staff members remove the volatile reagents by opening the sealed doors 3 at the front and back of the volatile reagent storage chamber 2. Since the reagents are sealed in the sealed sleeve from beginning to end, they can avoid any contact with the volatiles throughout the process. For reagents that have not evaporated, simply open the sealing door of the access sealing channel 101, remove the sealing sleeve, separate the lower sealing half 9 and the upper sealing half 10, and take out the reagent tube.

[0031] Example 2: The volatile detection device 5 rotates at an extremely slow speed. It integrates a gas sensor module, a signal processing circuit, and a control unit. It is also equipped with a miniature air pump to actively extract gas from the sealed sleeve during detection. The time required for the 4-axis motor to rotate one revolution is at least 1 hour. This is because some reagent tubes need to be left to stand. The extremely slow rotation speed ensures that the reagents in the reagent tubes can still settle and settle when the sealing sleeve fixing plate 801, rotating plate 802, pushing mechanism 803 and the sealing sleeve as a whole are rotating. Moreover, the longer rotation time also allows the reagents sufficient time to evaporate, allowing the volatiles in the sealing sleeve to reach a high concentration, which is convenient for detection. A sealing mark line 1010 is provided at the lower part of the upper pipe 1001. There are two sealing mark lines 1010. The upper sealing mark line 1010 corresponds to the secondary annular sealing ring 904, and the lower sealing mark line 1010 corresponds to the primary annular sealing ring 903. When the upper perforation 804 of a certain sealing sleeve is aligned with the axis of the pushing mechanism 11, the controller of the motor 4 sends a signal to stop the rotation of the motor 4, and the control unit of the volatile detection device 5 sends a command to the solenoid valve of the cylinder 1103 to drive the cylinder 1103 to extend. The volatile detection device 5 is set with low-risk concentration threshold and high-risk concentration threshold. After the cylinder 1103 extends and moves down, the push rod 1108 pushes open the movable sealing cover 1006 to form an airflow channel. The micro air pump inside the volatile detection device 5 starts and draws the gas in the sealing sleeve into the sensor chamber. It continuously detects for about 5 seconds to obtain the volatile concentration value. The control unit compares the obtained volatile concentration value with the preset low-risk concentration threshold and high-risk concentration threshold. If the detection does not reach the low-risk concentration threshold, the control unit sends a command, the cylinder 1103 retracts and resets, the motor 4 resumes rotation, and the next sealing sleeve is sent into the detection position. The annular snap ring 1009 of the previously detected sealing sleeve is above the initial annular sealing ring 903, and both sealing marking lines 1010 are above the initial annular sealing ring 903. The staff can see from the outside that the reagent inside the sealing sleeve has not evaporated. The staff can open the sealing sleeve and take out the reagent tube. If the reagent evaporation is detected to be at a low-risk concentration threshold, the control unit continues to increase the stroke of cylinder 1103. Cylinder 1103 continues to move downward, and the annular snap ring 1009 squeezes past the initial annular sealing ring 903. The annular snap ring 1009 and the initial annular sealing ring 903 are hooked and sealed, and the sealing sleeve is firmly sealed to prevent the evaporating gas from escaping. At this time, the sealing mark line 1010 at the lower position moves down, and the staff can only see the sealing mark line 1010 at the upper position outside the sealing sleeve. If necessary, the staff can still open the sealing sleeve by using greater external force. If the sealing sleeve cannot be opened, the corrugated section 1002 can be stretched to break it from here without damaging the reagent tube. Alternatively, the corrugated section 1002 is a thin-walled extensible structure, and the corrugated section can be stretched upward to cause plastic deformation or tearing, thereby breaking the sealing sleeve and removing the reagent tube. If the reagent volatilization is detected to be at a high-risk concentration threshold, the control unit further increases the stroke of cylinder 1103, and cylinder 1103 moves down in depth. The annular snap ring 1009 continues to move down and squeezes past the secondary annular sealing ring 904. The annular snap ring 1009 and the secondary annular sealing ring 904 are in a hook-and-seal state, and the sealing sleeve is in a tight seal state. At this time, the two sealing marking lines 1010 are completely hidden and cannot be seen from the outside of the sealing sleeve. Even if a person who comes into contact with the sealing sleeve uses a lot of force, it is difficult to open the sealing sleeve. The sealing sleeve and the reagent tube are disposed of in a harmless manner. If a sensor malfunction or gas path blockage occurs during the detection process, the control unit of the volatile detection device 5 will issue an audible and visual alarm, stop the operation of the motor 4 and the cylinder 1103, and wait for manual intervention. Depending on the volatility characteristics of different reagents, the volatility detection device 5 can select different types of sensors: For organic solvents such as ethanol, acetone, and benzene compounds, a photoionization detector is preferred, with a detection range of 0-2000 ppm and an accuracy of 0.1 ppm. For acidic or alkaline volatiles, such as hydrochloric acid and ammonia, an electrochemical sensor is preferred, with a detection range of 0-100 ppm; For general volatile organic compounds, semiconductor gas sensors, such as the MQ-135, can be used. They are low in cost and suitable for applications with high threshold values. For multiple mixed volatiles, a gas chromatography-sensor coupled module can be used, which, although more expensive, can achieve qualitative and quantitative analysis. Regardless of the type of sensor used, the volatile detection device 5 integrates a temperature and humidity compensation circuit to reduce the impact of ambient temperature and humidity on the detection results. It also has an internal self-test program that automatically calibrates the zero point each time it is turned on and resets the baseline to zero after each detection cycle. The solenoid valves of the motor 4 and cylinder 1103, as well as the volatile detection device 5, are all installed outside the sealed chamber 1. There are no electrical components inside the sealed chamber 1, which completely avoids the risk of electrical sparks coming into contact with volatile gases. The shells of the sealed chamber 1 and the volatile reagent placement chamber 2 are both made of antistatic materials and are equipped with grounding terminals.

[0032] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A reagent anti-volatile sealing device for a biological detection station, comprising a sealed chamber (1), a volatile detection device (5) disposed above the sealed chamber (1), and a volatile reagent placement chamber (2) separated from the sealed chamber (1) by a base plate (6), wherein a door-equipped access and placement sealing channel (101) is provided on one side of the sealed chamber (1), and sealing doors (3) are provided at both the front and rear of the volatile reagent placement chamber (2), characterized in that: The sealing chamber (1) and the volatile reagent placement chamber (2) are equipped with a falling mechanism (8). The falling mechanism (8) includes a sealing sleeve fixing plate (801), a rotating plate (802), a pushing mechanism (803), an upper through hole (804), and a falling hole (805). The sealing sleeve fixing plate (801) is located in the sealing chamber (1) and has an upper through hole (804). The rotating plate (802) is attached to the bottom plate (6) and has a falling hole (805). The upper through hole (804) and the falling hole (805) are staggered. The pushing mechanism (803) is located below the rotating plate (802) and its blades are close to the rear of the falling hole (805). The top of the sealed chamber (1) is fixedly installed with a motor (4). The rotating shaft of the motor (4) is fixedly connected to the sealing sleeve fixing plate (801), the rotating plate (802) and the pushing mechanism (803), driving the three components to rotate synchronously. The sealing sleeve fixing plate (801) is fixedly installed at the upper through hole (804) to install an independently detachable sealing sleeve. The sealing sleeve is formed by connecting the lower sealing half sleeve (9) and the upper sealing half sleeve (10) to accommodate the reagent tube. Below the volatile detection device (5) is a pushing mechanism (11) for pressing down the sealing sleeve and forming an airflow channel. The air inlet of the volatile detection device (5) is connected to the air pipe (1101) of the pushing mechanism (11) for detecting the concentration of volatiles in the sealing sleeve. The volatile detection device (5) includes a gas sensor module, a signal processing circuit, a control unit and a micro air pump. The control unit is electrically connected to the motor (4) and the cylinder (1103) of the pushing mechanism (11) to control the start and stop of the motor (4), the speed and the extension stroke of the cylinder (1103).

2. The reagent anti-volatilization sealing device for a biological detection station according to claim 1, characterized in that: The lower sealing half-set (9) includes a lower tube (901), an annular slot (902), a primary annular sealing ring (903) and a secondary annular sealing ring (904). The inner side wall of the lower tube (901) is provided with an annular slot (902). The primary annular sealing ring (903) and the secondary annular sealing ring (904) are arranged sequentially from top to bottom in the annular slot (902). The upper sealing half-set (10) includes an upper tube (1001), and the lower part of the upper tube (1001) is provided with an annular snap ring (1009) that can be inserted into an annular slot (902) to seal with the primary annular sealing ring (903) and the secondary annular sealing ring (904).

3. The reagent anti-volatility sealing device for a biological detection station according to claim 2, characterized in that: The upper part of the upper tube (1001) is provided with a retractable corrugated section (1002).

4. The reagent anti-volatilization sealing device for a biological detection station according to claim 3, characterized in that: The top of the upper tube (1001) is provided with an extension body (1003), and the interior of the extension body (1003) is provided with an inner tube (1004). The top of the upper tube (1001) is provided with a protruding tube (1005) located inside the extension body (1003). A movable sealing cover (1006) is provided between the inner tube (1004) and the protruding tube (1005). The movable sealing cover (1006) can cover the protruding tube (1005). There is a gap between the side of the movable sealing cover (1006) and the inner wall of the extension body (1003). A spring (1007) is sleeved on the protruding tube (1005). The spring (1007) always pushes the movable sealing cover (1006) upward to block the lower opening of the inner tube (1004).

5. The reagent anti-volatilization sealing device for a biological detection station according to claim 4, characterized in that: The pushing mechanism (11) includes a vent pipe (1101), a lower pressure plate (1102), a cylinder (1103), a connector (1104), a pressure pipe (1105), a corrugated sealing pipe (1106), a sealing ring (1107), and a push rod (1108). The cylinder (1103) is fixedly installed below the volatile detection device (5), and its piston rod is fixedly connected to the lower pressure plate (1102). One end of the air pipe (1101) is connected to the air inlet of the volatile detection device (5), and the other end is connected to the pressure pipe (1105). The pressure pipe (1105) is integrally connected to the corrugated sealing pipe (1106). The lower end of the corrugated sealing pipe (1106) is provided with a sealing ring (1107). The sealing ring (1107) can be pressed against the top of the extension body (1003) to form a sealing channel. A push rod (1108) is fixedly installed at the center of the connector (1104). The push rod (1108) extends into the inner tube (1004) to press down the movable sealing cover (1006) to separate it from the inner tube (1004) and form an airflow channel. The base plate (6) is provided with a through hole (7) coaxial with the push rod (1108).

6. The reagent anti-volatilization sealing device for a biological detection station according to claim 5, characterized in that: The lower outer side of the upper tube (1001) is provided with two sealing mark lines (1010). The upper sealing mark line (1010) corresponds to the secondary annular sealing ring (904), and the lower sealing mark line (1010) corresponds to the primary annular sealing ring (903).

7. The reagent anti-volatilization sealing device for a biological detection station according to claim 6, characterized in that: The inner surfaces of the lower tube (901) and the upper tube (1001) are provided with a buffer layer, and the bottom of the lower tube (901) is provided with a guide arc surface (905).

8. The reagent anti-volatilization sealing device for a biological detection station according to claim 7, characterized in that: The sealing sleeve fixing plate (801) is provided with an upper fixing ring (12) at the upper perforation (804) position. The top of the upper sealing half sleeve (10) is fixed with a lower fixing ring (1008) outside the extension body (1003). The lower fixing ring (1008) and the upper fixing ring (12) are detachably connected by pasting or magnetic adsorption.

9. A reagent anti-volatilization sealing device for a biological detection station according to claim 8, characterized in that: The control unit of the volatile detection device (5) is equipped with a low-risk concentration threshold and a high-risk concentration threshold. The control unit controls the extension stroke of the cylinder (1103) according to the detection results. When the detected concentration is below the low-risk concentration threshold, the cylinder (1103) extends and immediately retracts to reset, the annular snap ring (1009) is positioned above the initial annular seal ring (903), and both sealing marking lines (1010) are visible; When the detected concentration reaches the low-risk concentration threshold, the cylinder (1103) continues to increase the first stroke, so that the annular snap ring (1009) passes over the initial annular sealing ring (903) and is in a hook-and-seal state, with only the sealing mark line (1010) at the top visible; When the detected concentration reaches or exceeds the high-risk threshold, the cylinder (1103) continues to increase the second stroke, so that the annular snap ring (1009) passes over the secondary annular sealing ring (904) and is in a hook-and-seal state, and both sealing marking lines (1010) are hidden.

10. A reagent anti-volatilization sealing device for a biological detection station according to claim 9, characterized in that: The motor (4), cylinder (1103), its solenoid valve, and volatile detection device (5) are all installed outside the sealed chamber (1). The shells of the sealed chamber (1) and the volatile reagent placement chamber (2) are made of antistatic material and are equipped with grounding terminals.

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