A foldable clinical test reagent refrigeration box temperature control system based on an intelligent sensing system

CN122774792APending Publication Date: 2026-09-18GUANGAN DISTRICT PEOPLES HOSPITAL
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Patent Information

Application Number
CN202610907474.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-06-23
Publication Date
2026-09-18

AI Technical Summary

Technical Problem

同时,可折叠盒体在展开、半折叠或收纳状态转换过程中,相邻盒段之间的导温路径和温度分布会发生变化;盒盖开启和关闭过程也会对靠近盒盖区域或气流通道区域的温度测量结果产生扰动

Benefits of technology

[0030] First, this invention can obtain temperature measurement data corresponding to the placement location of each clinical laboratory reagent. By setting up an intelligent sensing system including a reagent proximity temperature sensor group, a box section wall temperature sensor group, a cross-section reference temperature sensor group, a folding angle sensor, and a lid status sensor, this invention refines the temperature measurement object from the overall temperature of the refrigerated box's internal space to the reagent position temperature data corresponding to each reagent temperature measuring seat. Therefore, when clinical laboratory reagents are distributed in different insulated box sections and different placement locations, temperature measurement results that more closely reflect the actual placement location of the reagents can be obtained, meeting the application requirements of temperature measurement technology solutions.

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Abstract

The application discloses a foldable clinical test reagent refrigeration box temperature control system based on an intelligent sensing system, which comprises a foldable refrigeration box body, a reagent bearing assembly, an intelligent sensing system, a temperature measurement calibration assembly, a partition temperature control execution assembly and an edge temperature control controller. The foldable refrigeration box body comprises at least two heat preservation box segments and a folding temperature guide connecting assembly, and a cross-segment reference temperature guide cavity is formed in the folding temperature guide connecting assembly. The intelligent sensing system collects the temperature of reagents, the wall temperature of the box segment, the cross-segment reference temperature, the folding angle and the state of the box cover. The temperature measurement calibration assembly generates equivalent temperature data of the reagent position. The edge temperature control controller controls the partition temperature control execution assembly according to the equivalent temperature data. The system is used for temperature measurement and partition temperature control of clinical test reagents in the foldable refrigeration box.
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Description

Technical Field

[0001] This invention relates to the field of temperature measurement and temperature control technology, and in particular to a temperature control system for a foldable clinical test reagent refrigerator based on an intelligent sensing system. Background Technology

[0002] Clinical laboratory reagents typically need to be maintained within a specified temperature range during temporary storage, transportation, or on-site use. For scenarios such as mobile testing, emergency treatment, and intra-hospital multi-departmental transfer, refrigerated containers usually need to simultaneously possess portable storage, low-temperature maintenance, and temperature measurement and control functions. Existing portable refrigeration devices generally create a refrigerated environment through refrigeration components and collect temperature data within the refrigerated space through temperature sensors or intelligent sensing systems. The temperature control system then controls the refrigeration components based on the collected temperature data.

[0003] For example, patent publication number CN201662293U discloses a field folding refrigerator, which includes a compressor refrigeration cycle system, an air-cooling cycle system, a temperature control system, a folding frame, and a heat insulation structure. The temperature control system employs a digital temperature acquisition and control system, the folding frame is a foldable metal frame, and the heat insulation structure is a foldable cover surrounding the metal frame. This folding refrigerator can be used for freezing or refrigerating temperature-sensitive items such as pharmaceuticals, blood products, vaccines, and biological products under emergency medical rescue or field conditions. The patent also discloses a method for real-time detection and display of the internal temperature of the folding refrigerator using a built-in temperature sensor, and for adjusting the temperature control system accordingly.

[0004] The aforementioned existing technologies enable the unfolding, folding, and storage of foldable refrigerators, as well as the acquisition and control of internal temperature. However, their temperature detection primarily targets the overall temperature of the interior space or a limited number of measurement points. For clinical laboratory reagent refrigerators, multiple reagent containers are typically distributed in different locations. These locations have varying distances from the refrigeration airflow, the container walls, the lid, and the folding connections, potentially leading to differences in local temperature conditions. Furthermore, the temperature conduction path and distribution between adjacent sections change during the unfolding, semi-folding, or folding process. The opening and closing of the lid also disturbs temperature measurements near the lid or airflow channels. Therefore, relying solely on a single point temperature or a limited number of measurement points within the container makes it difficult to obtain comprehensive temperature data for each clinical laboratory reagent placement location.

[0005] Therefore, the main technical problem that still needs to be solved in the temperature measurement and control process of foldable clinical test reagent refrigerator boxes is: how to obtain temperature measurement data corresponding to the placement position of each clinical test reagent when the folded state of the foldable refrigerator box, the state of the lid, and the temperature distribution of different sections of the box change, so as to provide a temperature measurement basis for zoned temperature control. Summary of the Invention

[0006] To overcome the aforementioned technical deficiencies, the present invention aims to provide a temperature control system for a foldable clinical laboratory reagent refrigerator based on an intelligent sensing system. This invention, through the installation of reagent-carrying components forming multiple reagent temperature measurement seats within a foldable refrigerator body comprised of at least two insulated box sections and a cross-section reference temperature-conducting cavity, and the configuration of an intelligent sensing system including a reagent proximity temperature sensor group, a box section wall temperature sensor group, a cross-section reference temperature sensor group, a folding angle sensor, and a lid status sensor, allows a temperature measurement calibration component to generate reagent position equivalent temperature data based on data collected by the intelligent sensing system. Then, an edge temperature controller controls a zone temperature control execution component based on this reagent position equivalent temperature data. This solves the problem of difficulty in obtaining temperature measurement data corresponding to each reagent placement position and performing zone temperature control based on this data under varying conditions (folded state, lid state, and temperature distribution changes across different box sections) in foldable clinical laboratory reagent refrigerators.

[0007] This invention discloses a temperature control system for a foldable clinical test reagent refrigerator based on an intelligent sensing system, including a foldable refrigerator body, a reagent carrying component, an intelligent sensing system, a temperature measurement and calibration component, a zoned temperature control execution component, and an edge temperature control controller;

[0008] The foldable refrigerator box includes at least two insulated box sections, a foldable temperature-conducting connection assembly connecting adjacent insulated box sections, and a box lid. A cross-section reference temperature-conducting cavity is formed within the foldable temperature-conducting connection assembly.

[0009] The reagent carrier components are respectively set in each heat preservation box section, forming multiple reagent temperature measuring seats;

[0010] The intelligent sensing system includes a reagent proximity temperature sensor group, a box section wall temperature sensor group, a cross-section reference temperature sensor group, a folding angle sensor, and a box lid status sensor.

[0011] The temperature measurement and calibration component generates reagent site equivalent temperature data based on data collected by the intelligent sensing system.

[0012] The edge temperature controller controls the zone temperature control execution component based on the equivalent temperature data of the reagent position.

[0013] Preferably, the reagent temperature measuring seat includes a bottom temperature-conducting part and a lateral limiting part; the reagent proximity temperature sensor group includes a bottom temperature sensor and a lateral temperature sensor, and each reagent temperature measuring seat is provided with at least one bottom temperature sensor and at least one lateral temperature sensor, with the bottom temperature sensor disposed on the bottom temperature-conducting part and the lateral temperature sensor disposed on the lateral limiting part.

[0014] Preferably, the bottom temperature-conducting part includes a temperature-conducting base, the lateral limiting part includes a lateral temperature-conducting clip, and the reagent temperature measuring seat also includes a sensor isolation groove; the bottom temperature sensor is embedded in the temperature-conducting base, the lateral temperature sensor is embedded in the lateral temperature-conducting clip, and the sensor isolation groove is disposed between two adjacent reagent temperature measuring seats.

[0015] Preferably, the box section wall temperature sensor group includes an air inlet side wall temperature sensor and a return air side wall temperature sensor; the air inlet side wall temperature sensor is located on the side of the temperature-conducting airflow entering the corresponding insulation box section formed by the zone temperature control execution component, and the return air side wall temperature sensor is located on the side of the temperature-conducting airflow returning the corresponding insulation box section formed by the zone temperature control execution component.

[0016] Preferably, the temperature measurement calibration component includes a sensor consistency calibration unit, a folding state compensation unit, a lid disturbance screening unit, and a reagent location temperature fusion unit. The sensor consistency calibration unit generates calibrated temperature data based on the original temperature data from the reagent proximity temperature sensor group, the box segment wall temperature sensor group, and the cross-segment reference temperature sensor group. The folding state compensation unit generates a cross-segment temperature difference compensation value based on the folding angle data collected by the folding angle sensor and the data collected by the cross-segment reference temperature sensor group. The lid disturbance screening unit determines the temperature sensor channels participating in temperature fusion based on the lid state data collected by the lid state sensor. The reagent location temperature fusion unit generates equivalent temperature data for the reagent location based on the calibrated temperature data, the cross-segment temperature difference compensation value, and the temperature sensor channels participating in temperature fusion.

[0017] Preferably, the sensor consistency calibration unit generates the calibrated temperature data according to the following formula:

[0018]

[0019] in, For the first intelligent sensing system Temperature data after calibration of each temperature sensor. For the first intelligent sensing system Raw temperature data from each temperature sensor. For the first intelligent sensing system Gain calibration coefficients for each temperature sensor. For the first intelligent sensing system Zero-point calibration value of each temperature sensor. Number the temperature sensor.

[0020] Preferably, the sensor consistency calibration unit is provided with a reference sampling state table, which includes the lid closing state, folding angle range, and execution state of the zone temperature control execution component. When the lid state data collected by the lid state sensor, the folding angle data collected by the folding angle sensor, and the execution state of the zone temperature control execution component meet the reference sampling state table, the sensor consistency calibration unit updates the gain calibration coefficient and zero-point calibration value of the corresponding temperature sensor according to the calibrated temperature data of the cross-segment reference temperature sensor group.

[0021] Preferably, the folding state compensation unit is provided with a folding angle interval table and a cross-segment temperature difference compensation table; the cross-segment reference temperature sensor group includes a first cross-segment temperature sensor and a second cross-segment temperature sensor, the first cross-segment temperature sensor is disposed at one end of the cross-segment reference temperature conducting cavity near one insulation box segment, and the second cross-segment temperature sensor is disposed at one end of the cross-segment reference temperature conducting cavity near another adjacent insulation box segment; the folding state compensation unit determines the folding angle interval according to the folding angle interval table, and determines the cross-segment temperature difference compensation value according to the calibrated temperature data of the first cross-segment temperature sensor and the second cross-segment temperature sensor.

[0022] Preferably, the lid disturbance screening unit is equipped with an opening time counter and a disturbance channel marking table; when the lid status sensor collects the lid opening state, the lid disturbance screening unit generates opening duration data according to the opening time counter, and determines the temperature sensor channel participating in temperature fusion according to the opening duration data, the folding angle range and the disturbance channel marking table.

[0023] Preferably, it also includes a temperature measurement self-calibration component; the temperature measurement self-calibration component includes a standard thermal pulse element and a sensor response determination unit, the standard thermal pulse element is set in the cross-segment reference temperature conduction cavity, and the sensor response determination unit is connected to the cross-segment reference temperature sensor group and the edge temperature control controller respectively, and the sensor response determination unit generates a channel validity mark based on the temperature change data before and after the standard thermal pulse element is activated.

[0024] Preferably, the temperature measurement self-calibration component further includes a self-calibration trigger unit, which is connected to the folding angle sensor, the lid status sensor, and the cross-segment reference temperature sensor group. The self-calibration trigger unit is provided with a self-calibration angle interval table, and triggers a standard thermal pulse when the folding angle data collected by the folding angle sensor crosses two adjacent self-calibration angle intervals in the self-calibration angle interval table, and the lid status sensor collects the lid closed state.

[0025] Preferably, the temperature measurement calibration component further includes an abnormal channel replacement unit; the abnormal channel replacement unit determines the abnormal temperature sensor channel according to the channel validity mark, and removes the abnormal temperature sensor channel from the temperature sensor channels participating in temperature fusion; the abnormal channel replacement unit generates replacement temperature data according to the calibrated temperature data of adjacent reagent temperature measuring seats in the same insulation box segment, the calibrated temperature data of the box segment wall temperature sensor group, and the calibrated temperature data of the cross-segment reference temperature sensor group.

[0026] Preferably, the zoned temperature control execution component includes a semiconductor cooling module, a zoned temperature-conducting duct, a first airflow regulator, a second airflow regulator, and a temperature-conducting opening regulator; the zoned temperature-conducting duct includes at least two box-section temperature-conducting branches, each of which includes a first box-section temperature-conducting branch and a second box-section temperature-conducting branch corresponding to different insulation box sections; the first airflow regulator is disposed in the first box-section temperature-conducting branch, the second airflow regulator is disposed in the second box-section temperature-conducting branch, and the temperature-conducting opening regulator is disposed in the cross-section reference temperature-conducting cavity.

[0027] Preferably, the edge temperature controller includes a cross-segment equalization control unit. The cross-segment equalization control unit generates a cooling power control command, a first air volume control command, a second air volume control command, and a temperature conduction opening control command based on the folding angle data collected by the folding angle sensor, the cross-segment reference temperature data collected by the cross-segment reference temperature sensor group, and the equivalent temperature data of the reagent positions in different insulation box segments.

[0028] Preferably, it also includes a temperature measurement and recording unit, each reagent temperature measuring seat is equipped with a seat number; the temperature measurement and recording unit is connected to the edge temperature controller, and forms a temperature measurement record by the seat number, the reagent position equivalent temperature data, the folding angle data collected by the folding angle sensor, the lid status data collected by the lid status sensor, the cooling power control command, the first air volume control command, the second air volume control command, and the temperature conduction opening control command.

[0029] Compared with existing technologies, the above technical solution has the following advantages:

[0030] First, this invention can obtain temperature measurement data corresponding to the placement location of each clinical laboratory reagent. By setting up an intelligent sensing system including a reagent proximity temperature sensor group, a box section wall temperature sensor group, a cross-section reference temperature sensor group, a folding angle sensor, and a lid status sensor, this invention refines the temperature measurement object from the overall temperature of the refrigerated box's internal space to the reagent position temperature data corresponding to each reagent temperature measuring seat. Therefore, when clinical laboratory reagents are distributed in different insulated box sections and different placement locations, temperature measurement results that more closely reflect the actual placement location of the reagents can be obtained, meeting the application requirements of temperature measurement technology solutions.

[0031] Secondly, this invention can reduce the impact of changes in the folding state of the foldable refrigerator body on temperature measurement results. This invention incorporates a cross-segment reference temperature-conducting cavity within the folding temperature-conducting connection assembly, and collects reference temperature data between adjacent insulated box segments using a cross-segment reference temperature sensor group. Simultaneously, it combines this data with folding angle data collected by a folding angle sensor to generate a cross-segment temperature difference compensation value. Therefore, when the foldable refrigerator body is in an unfolded, semi-folded, or stowed state, it can compensate for changes in temperature distribution between adjacent insulated box segments, reducing the deviation in reagent temperature measurement caused by changes in folding state.

[0032] Third, this invention can reduce the impact of lid opening disturbances on temperature measurement data. This invention uses a lid status sensor to collect the lid open and closed states, and a lid disturbance screening unit determines the temperature sensor channels participating in temperature fusion based on the lid opening duration data, folding angle range, and a disturbance channel marking table. For temperature sensor channels affected by lid opening, their participation weight can be reduced or they can be temporarily removed, thereby preventing local temperature disturbances generated at the moment the lid is opened from directly participating in the generation of equivalent temperature data for the reagent position.

[0033] Fourth, this invention improves the consistency of measurement data from multiple temperature sensors. The invention uses a sensor consistency calibration unit to calibrate the raw temperature data from the reagent proximity temperature sensor group, the box section wall temperature sensor group, and the cross-section reference temperature sensor group, generating calibrated temperature data. This calibration process combines gain calibration coefficients and zero-point calibration values, ensuring that data output from different installation locations, different measurement channels, and different sensor types are unified under the same temperature measurement reference, thereby improving the consistency of the basic data for subsequent reagent site temperature fusion. Attached Figure Description

[0034] Figure 1 This is a schematic diagram of the overall system structure of a temperature control system for a foldable clinical laboratory reagent refrigerator based on an intelligent sensing system according to the present invention.

[0035] Figure 2 This is a schematic diagram showing the arrangement of the foldable refrigerator box, reagent temperature measuring base, and temperature sensor in this invention.

[0036] Figure 3 This is a schematic diagram of the data processing flow of the temperature measurement and calibration component in this invention;

[0037] Figure 4 This is a schematic diagram of the working process of the temperature measurement self-calibration component and the abnormal channel replacement unit in this invention;

[0038] Figure 5 This is a schematic diagram illustrating the collaborative relationship between the zoned temperature control execution component and the temperature measurement and recording unit in this invention;

[0039] Figure 6 This is a comparison curve of the temperature recovery of the present invention and the comparative example after the box lid was opened and disturbed.

[0040] Explanation of reference numerals in the attached figures:

[0041] 1 is the first insulation box section; 2 is the second insulation box section; 3 is the folding temperature-conducting connection assembly; 4 is the cross-section reference temperature-conducting cavity; 5 is the reagent temperature measuring seat; 6 is the bottom temperature sensor; 7 is the side temperature sensor; 8 is the first cross-section temperature sensor; 9 is the second cross-section temperature sensor; 10 is the air inlet side wall temperature sensor; 11 is the air return side wall temperature sensor; 12 is the folding angle sensor; 13 is the lid status sensor. DETAILED DESCRIPTION

[0042] To enable those skilled in the art to understand and implement this technical solution, a temperature control system for a foldable clinical laboratory reagent refrigerator based on an intelligent sensing system is further described below with reference to the accompanying drawings. This embodiment focuses on the acquisition, calibration, compensation, and fusion of temperature measurement data. The intelligent sensing system acquires temperature and status data corresponding to the placement location of the clinical laboratory reagents, and generates equivalent temperature data for the reagent location through a temperature measurement calibration component, thereby providing a temperature measurement basis for subsequent zoned temperature control. In this embodiment, the intelligent sensing system is used to form a temperature measurement data chain including reagent proximity temperature, section wall temperature, cross-section reference temperature, folding angle, and lid status, making temperature measurement, temperature calibration, and temperature data processing the main technical content of the system. It should be understood that the following embodiments are used to illustrate the specific implementation methods of temperature measurement, temperature calibration, folding state compensation, lid disturbance screening, abnormal channel replacement, and zoned temperature control in this technical solution, and do not limit the specific dimensions, material types, or sensor brands of each structural component.

[0043] like Figure 1 and Figure 2As shown, in one embodiment, the temperature control system of the foldable clinical test reagent refrigerator based on an intelligent sensing system includes a foldable refrigerator body, a reagent carrying component, an intelligent sensing system, a temperature measurement and calibration component, a zoned temperature control execution component, and an edge temperature control controller. The foldable refrigerator body includes at least two insulated box segments, a foldable temperature-conducting connection component 3 connecting adjacent insulated box segments, and a lid. For ease of explanation, the at least two insulated box segments may specifically include a first insulated box segment 1 and a second insulated box segment 2; when the number of insulated box segments is greater than two, the remaining insulated box segments can be configured with corresponding reagent carrying components, box segment wall temperature sensor groups, and box segment temperature-conducting branches in the same manner. The foldable temperature-conducting connection component 3 is disposed between adjacent insulated box segments to realize the foldable connection between adjacent insulated box segments, and forms a cross-segment reference temperature-conducting cavity 4 inside it. The cross-segment reference temperature-conducting cavity 4 extends along the connection direction between adjacent insulated box segments, with its two ends respectively close to the two adjacent insulated box segments. The cross-segment reference temperature conduction cavity 4 serves as a temperature measurement reference space between adjacent insulation box segments. It is used to provide the cross-segment reference temperature measurement position and to arrange the cross-segment reference temperature sensor group to collect the reference temperature change between adjacent insulation box segments when the folding state changes.

[0044] The reagent carrying components are respectively set within each insulated box section, forming multiple reagent temperature measuring seats 5. Each reagent temperature measuring seat 5 is used to hold a clinical laboratory reagent container, which can be a reagent tube, reagent bottle, pre-filled reagent kit, or reagent compartment with identification tag. The reagent temperature measuring seat 5 is not only used for mechanical positioning of the reagent container, but also for forming a temperature measurement position adjacent to the reagent container. Through the above arrangement, the temperature measurement object changes from the temperature of the traditional internal space of the refrigerator box to the temperature measurement data corresponding to each reagent placement position, which can be used for location-specific temperature monitoring of clinical laboratory reagents.

[0045] In one embodiment, the reagent temperature measuring holder 5 includes a bottom temperature-conducting part and a lateral limiting part. The bottom temperature-conducting part is disposed at a corresponding position on the bottom of the reagent container, and the lateral limiting part is disposed at a corresponding position on the side wall of the reagent container. The reagent proximity temperature sensor group includes a bottom temperature sensor 6 and a lateral temperature sensor 7, with each reagent temperature measuring holder 5 correspondingly provided with at least one bottom temperature sensor 6 and at least one lateral temperature sensor 7. The bottom temperature sensor 6 is disposed on the bottom temperature-conducting part, and the lateral temperature sensor 7 is disposed on the lateral limiting part. The bottom temperature sensor 6 is used to collect temperature data of the area adjacent to the bottom of the reagent container, and the lateral temperature sensor 7 is used to collect temperature data of the area adjacent to the sides of the reagent container. The bottom temperature sensor 6 and the lateral temperature sensor 7 can be digital temperature sensors, thermistors, thin-film platinum resistance thermometers, or integrated temperature acquisition chips.

[0046] Furthermore, the bottom temperature-conducting part may include a temperature-conducting base, the lateral limiting part may include a lateral temperature-conducting clip, and the reagent temperature measuring seat 5 may also include a sensor isolation groove. The temperature-conducting base may be made of aluminum alloy sheet, stainless steel sheet, or thermally conductive composite material, and is positioned in contact with or adjacent to the bottom of the reagent container. The lateral temperature-conducting clip may be configured as an elastic clip or a semi-enclosed temperature-conducting sheet, and is positioned in contact with or adjacent to the side wall of the reagent container. The bottom temperature sensor 6 is embedded in the temperature-conducting base, and the lateral temperature sensor 7 is embedded in the lateral temperature-conducting clip. The sensor isolation groove is disposed between two adjacent reagent temperature measuring seats 5, and the sensor isolation groove may be an air isolation groove, a low thermal conductivity isolation groove, or an isolation groove with a thermal insulation strip, used to reduce thermal transfer interference between adjacent reagent temperature measuring seats 5.

[0047] like Figure 2 As shown, the box section wall temperature sensor group includes an inlet side wall temperature sensor 10 and a return side wall temperature sensor 11. The inlet side wall temperature sensor 10 is located on the side where the temperature-conducting airflow formed by the zone temperature control execution component enters the corresponding insulation box section, and the return side wall temperature sensor 11 is located on the side where the temperature-conducting airflow returns to the corresponding insulation box section. The inlet side wall temperature sensor 10 is used to collect box section wall temperature data near the temperature-conducting airflow entering the insulation box section, and the return side wall temperature sensor 11 is used to collect box section wall temperature data near the return side of the temperature-conducting airflow. Through the inlet side wall temperature sensor 10 and the return side wall temperature sensor 11, the temperature status at both ends of the temperature-conducting airflow path in each insulation box section can be obtained, providing box section wall temperature reference for reagent temperature fusion.

[0048] In one embodiment, the box section wall temperature data can be determined jointly by the calibrated temperature data of the inlet side wall temperature sensor 10 and the calibrated temperature data of the return air side wall temperature sensor 11. Both the calibrated temperature data of the inlet side wall temperature sensor 10 and the calibrated temperature data of the return air side wall temperature sensor 11 are obtained by calibrating the corresponding original temperature data using a sensor consistency calibration unit. Specifically, the box section wall temperature data can be generated as follows:

[0049]

[0050] in, For box section wall temperature data, The temperature data is the calibrated temperature data for the inlet side wall temperature sensor 10. The temperature data is the calibrated temperature data of the return air side wall temperature sensor 11. The inlet sidewall temperature fusion coefficient. The return air sidewall temperature fusion coefficient, and The inlet and return air sidewall temperature fusion coefficients are dimensionless coefficients, which can be determined through temperature-conducting airflow distribution tests within the insulation box section, or programmed into the edge temperature controller during factory calibration. Different insulation box sections can be configured with different inlet and return air sidewall temperature fusion coefficients.

[0051] For example, in a certain insulation box section, the calibrated temperature data of the inlet side wall temperature sensor 10 is 5.70℃, the calibrated temperature data of the return air side wall temperature sensor 11 is 6.30℃, the fusion coefficient of the inlet side wall temperature is 0.50, and the fusion coefficient of the return air side wall temperature is 0.50. Then, the wall temperature data of the box section is calculated as follows:

[0052]

[0053] The temperature unit in the above calculation is ℃, thus the wall temperature data of the corresponding insulation box section is 6.00℃.

[0054] The cross-segment reference temperature sensor group includes a first cross-segment temperature sensor 8 and a second cross-segment temperature sensor 9. The first cross-segment temperature sensor 8 is located at one end of the cross-segment reference temperature-conducting cavity 4 near one insulation box segment, and the second cross-segment temperature sensor 9 is located at one end of the cross-segment reference temperature-conducting cavity 4 near another adjacent insulation box segment. The cross-segment reference temperature-conducting cavity 4 can be formed by a flexible temperature-conducting tube, a bendable temperature-conducting groove, or a temperature-conducting cavity with an insulation outer layer. The folded temperature-conducting connection assembly 3 can include a flexible insulation hinge layer, a reference temperature-conducting hose, and a temperature-conducting opening adjustment component. The reference temperature-conducting hose forms the cross-segment reference temperature-conducting cavity 4, and the temperature-conducting opening adjustment component is located inside the cross-segment reference temperature-conducting cavity 4. The temperature-conducting opening adjustment component can be a miniature baffle, a flexible valve, a miniature damper, or an adjustable opening structure, used to adjust the opening of the temperature-conducting passage in the cross-segment reference temperature-conducting cavity 4.

[0055] The intelligent sensing system includes a reagent proximity temperature sensor group, a box section wall temperature sensor group, a cross-section reference temperature sensor group, a folding angle sensor 12, and a lid status sensor 13. The folding angle sensor 12 can be installed near the rotation axis of the folding temperature-conducting connection assembly 3, or at the hinge between adjacent insulated box sections. The folding angle sensor 12 can be a Hall angle sensor, a potentiometric angle sensor, a magnetically encoded angle sensor, or an inertial measurement sensor. The lid status sensor 13 is located at the engagement position between the lid and the insulated box section. The lid status sensor 13 can be a magnetic induction switch, a micro switch, a photoelectric switch, or a capacitive proximity switch, used to collect the lid's open and closed states.

[0056] like Figure 3As shown, the temperature measurement calibration component includes a sensor consistency calibration unit, a folding state compensation unit, a lid disturbance screening unit, and a reagent location temperature fusion unit. The sensor consistency calibration unit receives raw temperature data from the reagent proximity temperature sensor group, the box section wall temperature sensor group, and the cross-section reference temperature sensor group, and generates calibrated temperature data. Since different temperature sensors may differ in factory deviations, installation positions, thermal contact conditions, and sampling circuits, the sensor consistency calibration unit ensures that the output data from different temperature sensors are under a unified measurement reference.

[0057] In one implementation, the sensor consistency calibration unit generates calibrated temperature data according to the following standard mathematical expression:

[0058]

[0059] in, For the first intelligent sensing system Temperature data after calibration of each temperature sensor. For the first intelligent sensing system Raw temperature data from each temperature sensor. For the first intelligent sensing system Gain calibration coefficients for each temperature sensor. For the first intelligent sensing system Zero-point calibration value of each temperature sensor. The temperature sensors are numbered. These numbers distinguish different temperature sensor channels; for example, bottom temperature sensor 6, side temperature sensor 7, inlet air side wall temperature sensor 10, return air side wall temperature sensor 11, first span temperature sensor 8, and second span temperature sensor 9 each have different temperature sensor numbers. The gain calibration coefficient is dimensionless, and the unit of the zero-point calibration value is °C.

[0060] For example, if the original temperature data of the bottom temperature sensor 6 corresponding to a certain reagent temperature measuring base 5 is 5.80℃, the gain calibration coefficient of the bottom temperature sensor 6 is 0.98, and the zero-point calibration value of the bottom temperature sensor 6 is 0.12℃, then the calibrated temperature data of the bottom temperature sensor 6 is calculated as follows:

[0061]

[0062] The temperature unit in the above calculation is °C, thus the calibrated temperature data of the bottom temperature sensor 6 is 5.804 °C.

[0063] The sensor consistency calibration unit includes a reference sampling state table. This table includes the lid-closed state, folding angle ranges, and the execution state of the zoned temperature control actuators. In this embodiment, the reference sampling state table can be pre-stored in the memory of the edge temperature controller or written during factory calibration. The reference sampling state table can be established through factory calibration, during which the foldable refrigerator body is placed in multiple folding angle ranges, and the temperature stability of each temperature sensor is recorded in the lid-closed state, lid-open state, and different zoned temperature control execution states. Temperature stability can be determined by the temperature change over multiple consecutive sampling periods. For example, if the temperature data change of the same temperature sensor after calibration is less than 0.05℃ for five consecutive sampling periods, the temperature sensor is considered to be in a stable temperature state. State combinations that satisfy preset sampling conditions are written into the reference sampling state table. The reference sampling state table is used to define the conditions under which temperature sensor data can be used to update the gain calibration coefficient and zero-point calibration value.

[0064] For example, when the lid status sensor 13 detects that the lid is closed, the folding angle sensor 12 detects that the folding angle data is within a preset unfolding angle range, and the zoned temperature control actuator is in a stable operating state, the sensor consistency calibration unit updates the gain calibration coefficient and zero-point calibration value of the corresponding temperature sensor based on the calibrated temperature data of the cross-segment reference temperature sensor group. A stable operating state may include the semiconductor cooling module running continuously for a set time, the opening degrees of the first and second airflow regulators remaining unchanged, and the temperature conduction opening regulator being at a specified opening degree.

[0065] The folding state compensation unit includes a folding angle interval table and a cross-segment temperature difference compensation table. The folding angle interval table divides the folding angle data collected by the folding angle sensor 12 into multiple folding angle intervals, such as unfolded, semi-folded, and folded intervals. The cross-segment temperature difference compensation table records the correspondence between the temperature difference between the first cross-segment temperature sensor 8 and the second cross-segment temperature sensor 9 under different folding angle intervals and the cross-segment temperature difference compensation value. The folding angle interval table and the cross-segment temperature difference compensation table can be established during factory calibration. When establishing the cross-segment temperature difference compensation table, the foldable refrigerator can be maintained in multiple folding angle intervals, and calibrated temperature data from the first cross-segment temperature sensor 8 and the second cross-segment temperature sensor 9 can be collected under the same ambient temperature, the same refrigeration power, and the same simulated reagent load conditions. The corresponding cross-segment compensation coefficient is determined based on the cross-segment temperature difference distribution under different folding angle intervals. The cross-segment compensation coefficient can be determined by minimizing the difference between the equivalent temperature data of the reagent position corresponding to each reagent temperature measuring seat 5 and the measurement result of the independent reference thermometer. The folding state compensation unit determines the current folding angle range according to the folding angle range table, and determines the segment temperature difference compensation value according to the calibrated temperature data of the first segment temperature sensor 8 and the second segment temperature sensor 9.

[0066] In one specific implementation, the cross-segment temperature difference compensation value can be determined as follows:

[0067]

[0068] in, This is the cross-segment temperature difference compensation value. This is the cross-segment compensation coefficient corresponding to the current folding angle range. This is the calibrated temperature data for the first segment temperature sensor 8. This is the calibrated temperature data for the second segment temperature sensor 9. The segment compensation coefficient can be predetermined using the segment temperature difference compensation table, and the segment compensation coefficient is a dimensionless coefficient. The segment compensation coefficient can be different for different folding angle ranges. For example, the segment compensation coefficient for the unfolded range is 0.20, the segment compensation coefficient for the half-folded range is 0.35, and the segment compensation coefficient for the folded range is 0.50.

[0069] For example, the folding angle sensor 12 collects a folding angle of 63°, corresponding to a half-folding interval; the calibrated temperature data of the first segment temperature sensor 8 is 5.90℃, and the calibrated temperature data of the second segment temperature sensor 9 is 6.60℃. The segment compensation coefficient corresponding to the half-folding interval is 0.35. Then, the segment temperature difference compensation value is calculated as follows:

[0070]

[0071] The temperature unit in the above calculations is °C, resulting in a cross-segment temperature difference compensation value of -0.245 °C. This cross-segment temperature difference compensation value does not directly replace the data collected by the reagent proximity temperature sensor group, but rather serves as a compensation input in the reagent site temperature fusion process, reflecting the temperature shift caused by changes in the folding state between adjacent insulation box segments. Since the cross-segment temperature difference compensation value participates in the reagent site temperature fusion in the form of a temperature difference, the cross-segment compensation fusion coefficient is used to limit the correction range of this temperature difference on the equivalent temperature data of the reagent site.

[0072] The lid disturbance screening unit is equipped with a lid opening time counter and a disturbance channel marking table. When the lid status sensor 13 detects the lid is open, the lid disturbance screening unit generates lid opening duration data via the lid opening time counter. The disturbance channel marking table records the temperature sensor channels affected by lid opening under different lid opening duration data and different folding angle ranges. The disturbance channel marking table can be established through lid opening disturbance experiments. During establishment, the lid is opened under different folding angle ranges, and the temperature change amplitude of each temperature sensor channel during different lid opening durations is recorded. Temperature sensor channels whose temperature change amplitude exceeds a preset disturbance judgment value are written into the corresponding lid opening duration data and the disturbance channel marking table under the folding angle range. The preset disturbance judgment value can be determined based on the reagent refrigeration temperature measurement accuracy; for example, a temperature sensor channel whose temperature change amplitude exceeds 0.30℃ within 30 seconds can be marked as a disturbance channel. The lid disturbance screening unit determines the temperature sensor channels participating in temperature fusion based on the lid opening duration data, folding angle range, and disturbance channel marking table. For temperature sensor channels marked as disturbance channels, the lid disturbance screening unit can reduce their participation weight in the current fusion cycle or temporarily remove the temperature sensor channel. This can prevent local temperature surges caused by the moment the lid is opened from directly affecting the equivalent temperature data of the reagent sites.

[0073] For example, when the lid opening duration data is 18 seconds and the folding angle data corresponds to the half-folding interval, the disturbance channel marking table can mark the lateral temperature sensor channel 7 and the air inlet side wall temperature sensor channel 10, which are close to the lid opening side, as disturbance channels. In the current fusion cycle, the lid disturbance screening unit can remove the marked air inlet side wall temperature sensor channel 10 and retain the bottom temperature sensor channel 6, the lateral temperature sensor channel 7, and the return air side wall temperature sensor channel 11 of the corresponding reagent temperature measuring seat 5 to participate in temperature fusion; alternatively, it can set the fusion coefficient corresponding to the marked air inlet side wall temperature sensor channel 10 to zero and proportionally allocate its original fusion coefficient to the remaining temperature sensor channels participating in temperature fusion.

[0074] The reagent position temperature fusion unit generates equivalent temperature data for the reagent position based on the calibrated temperature data, the cross-segment temperature difference compensation value, and the temperature sensor channels involved in the temperature fusion. The equivalent temperature data corresponds to the reagent temperature measuring seat 5 and is used to represent the temperature measurement result at the corresponding reagent placement location. In one embodiment, the reagent position temperature fusion unit generates equivalent temperature data based on the calibrated temperature data of the bottom temperature sensor 6 corresponding to the same reagent temperature measuring seat 5, the calibrated temperature data of the side temperature sensor 7, the box segment wall temperature data corresponding to the insulation box segment where the reagent temperature measuring seat 5 is located, and the cross-segment temperature difference compensation value.

[0075] The reagent site equivalent temperature data can be generated using the following standard mathematical expression:

[0076]

[0077] in, This provides the equivalent temperature data for the reagent position corresponding to a reagent temperature measuring seat 5. This is the calibrated temperature data of the bottom temperature sensor 6 corresponding to the reagent temperature measuring base 5. This is the calibrated temperature data of the lateral temperature sensor 7 corresponding to the reagent temperature measuring seat 5. This refers to the wall temperature data of the insulation box section where the reagent temperature measuring seat 5 is located. This is the cross-segment temperature difference compensation value corresponding to the insulation box segment where the reagent temperature measuring seat 5 is located. The bottom temperature fusion coefficient, The lateral temperature fusion coefficient, The fusion coefficient of the box section wall temperature. The fusion coefficients are cross-segment compensation coefficients, and the sum of the bottom temperature fusion coefficient, lateral temperature fusion coefficient, box segment wall temperature fusion coefficient, and cross-segment compensation fusion coefficient is 1. These fusion coefficients are dimensionless and can be pre-stored based on the structure of the reagent temperature measuring seat 5, the size of the reagent container, the position of the insulation box segment, and the folding angle range, or obtained through experimental calibration during factory calibration. During calibration, the bottom temperature fusion coefficient, lateral temperature fusion coefficient, box segment wall temperature fusion coefficient, and cross-segment compensation fusion coefficient can be solved with the objective function of minimizing the variance between the equivalent temperature data of each reagent position corresponding to each reagent temperature measuring seat 5 and the true temperature measured by the standard thermometer.

[0078] For example, the calibrated temperature data of the bottom temperature sensor 6 corresponding to a certain reagent temperature measuring seat 5 is 5.80℃, the calibrated temperature data of the side temperature sensor 7 is 6.20℃, the wall temperature data of the insulation box section where the reagent temperature measuring seat 5 is located is 6.00℃, and the cross-section temperature difference compensation value is -0.245℃. Within this folding angle range, the bottom temperature fusion coefficient is 0.45, the side temperature fusion coefficient is 0.30, the box section wall temperature fusion coefficient is 0.20, and the cross-section compensation fusion coefficient is 0.05. The equivalent temperature data of the reagent position is calculated as follows:

[0079]

[0080] The temperature unit in the above calculation is °C, thus the equivalent temperature data of the reagent position corresponding to the reagent temperature measuring seat 5 is 5.65775 °C.

[0081] like Figure 4 As shown, in one embodiment, the temperature control system of the foldable clinical test reagent refrigerator based on the intelligent sensing system further includes a temperature measurement self-calibration component. The temperature measurement self-calibration component includes a standard thermal pulse element and a sensor response determination unit. The standard thermal pulse element is disposed within the cross-segment reference temperature conduction cavity 4, and can be a miniature resistance heating element, a flexible heating film, or a controlled heat source chip. The activation power and activation duration of the standard thermal pulse element are preset, causing a temperature change within the cross-segment reference temperature conduction cavity 4 that can be detected by the first cross-segment temperature sensor 8 and the second cross-segment temperature sensor 9. The sensor response determination unit is connected to the cross-segment reference temperature sensor group and the edge temperature controller, respectively, and generates a channel validity mark based on the temperature change data before and after the activation of the standard thermal pulse element.

[0082] In one embodiment, the sensor response determination unit can collect initial temperature data from the first span temperature sensor 8 and the second span temperature sensor 9 before the standard thermal pulse is activated, and collect response temperature data from the first span temperature sensor 8 and the second span temperature sensor 9 within a preset sampling window after the standard thermal pulse is activated. The preset sampling window can be a time period of 10 to 20 seconds after the standard thermal pulse is activated, or it can be set according to the heat capacity of the span reference temperature conducting cavity 4 and the activation power of the standard thermal pulse. The sensor response determination unit uses the difference between the response temperature data and the initial temperature data as the temperature change data, and generates a channel validity mark based on whether the temperature change data falls within the valid response range. The valid response range can be determined by factory calibration based on the activation power of the standard thermal pulse, the activation duration, and the heat capacity of the span reference temperature conducting cavity 4.

[0083] In one specific embodiment, before the standard thermal pulse device is activated, the calibrated temperature data of the first segment temperature sensor 8 is 5.90℃, and the calibrated temperature data of the second segment temperature sensor 9 is 6.60℃. After the standard thermal pulse device is activated at 0.8W power for 12 seconds, the calibrated temperature data of the first segment temperature sensor 8 is 6.18℃, and the calibrated temperature data of the second segment temperature sensor 9 is 6.89℃. The sensor response determination unit calculates the temperature change data of the first segment temperature sensor 8 and the second segment temperature sensor 9 respectively. The temperature change data of the first segment temperature sensor 8 is calculated as follows:

[0084]

[0085] The temperature change data of the second-segment temperature sensor 9 is calculated as follows:

[0086]

[0087] in, This data represents the temperature change of the first-segment temperature sensor 8 before and after the activation of the standard thermal pulse device. The temperature change data of the second segment temperature sensor 9 before and after the activation of the standard thermal pulse device is used. The temperature unit in the above calculation is °C. If the preset effective response range in the sensor response determination unit is 0.20 °C to 0.40 °C, the sensor response determination unit generates a channel validity mark indicating that the channel is valid for both the first segment temperature sensor 8 and the second segment temperature sensor 9. If the temperature change data of a certain segment temperature sensor is lower than 0.20 °C or higher than 0.40 °C, the sensor response determination unit marks the corresponding temperature sensor channel as an abnormal temperature sensor channel.

[0088] The temperature measurement self-calibration component also includes a self-calibration trigger unit. This trigger unit connects to the folding angle sensor 12, the lid status sensor 13, and the cross-section reference temperature sensor group. The trigger unit has a self-calibration angle interval table and triggers a standard thermal pulse when the folding angle data collected by the folding angle sensor 12 crosses two adjacent self-calibration angle intervals in the table, and the lid status sensor 13 detects the lid is closed. The self-calibration angle interval table can use the same angle boundaries as the folding angle interval table, or it can be independently established based on the bending sensitivity of the cross-section reference temperature-conducting cavity 4. Using this triggering method, the temperature measurement self-calibration component can calibrate the cross-section reference temperature sensor group after a change in the folding state, while avoiding the influence of external airflow disturbances on the calibration results when the lid is open.

[0089] The temperature measurement calibration assembly also includes an abnormal channel replacement unit. This unit identifies abnormal temperature sensor channels based on channel validity markers and removes them from the temperature sensor channels participating in temperature fusion. The unit generates replacement temperature data based on the calibrated temperature data of adjacent reagent temperature measuring seats 5 within the same insulation box segment, the calibrated temperature data of the box segment wall temperature sensor group, and the calibrated temperature data of the cross-segment reference temperature sensor group. This replacement temperature data is used to participate in reagent position temperature fusion in the current or next fusion cycle after the abnormal temperature sensor channel is removed, ensuring that the corresponding reagent temperature measuring seat 5 can still generate equivalent reagent position temperature data.

[0090] In one specific embodiment, the lateral temperature sensor 7 corresponding to a certain reagent temperature measuring seat 5 is marked as an abnormal temperature sensor channel. The calibrated temperature data of the lateral temperature sensors 7 corresponding to two adjacent reagent temperature measuring seats 5 are 6.10℃ and 6.24℃, respectively. The wall temperature data of the insulation box section corresponding to the reagent temperature measuring seat 5 is 6.00℃. The average calibrated temperature data of the cross-segment reference temperature sensor group can be obtained by averaging the calibrated temperature data of the first cross-segment temperature sensor 8 and the second cross-segment temperature sensor 9.

[0091]

[0092] in, This represents the average temperature data after calibration for the cross-segment reference temperature sensor group. This is the calibrated temperature data for the first segment temperature sensor 8. This refers to the calibrated temperature data of the second segment temperature sensor 9. For example, if the calibrated temperature data of the first segment temperature sensor 8 is 6.18℃ and the calibrated temperature data of the second segment temperature sensor 9 is 6.32℃, then the average calibrated temperature data of the segment reference temperature sensor group is calculated as follows:

[0093]

[0094] The temperature unit in the above calculation is ℃, thus the average temperature data of the cross-segment reference temperature sensor group after calibration is 6.25℃.

[0095] The abnormal channel replacement unit can generate replacement temperature data according to the following standard mathematical expression:

[0096]

[0097] in, To replace temperature data, This is the calibrated temperature data corresponding to an adjacent reagent temperature measuring seat 5. This is the calibrated temperature data corresponding to another adjacent reagent temperature measuring seat 5. This refers to the wall temperature data of the insulation box section where the reagent temperature measuring seat 5 is located. This represents the average temperature data after calibration for the cross-segment reference temperature sensor group. , , and These are the coefficients for calculating the substitution temperature, and The substitution temperature calculation coefficient is a dimensionless coefficient, which can be determined by the distance between adjacent reagent temperature measuring seats 5, the position of the box section wall temperature sensor group, and the position of the cross-section reference temperature conducting cavity 4.

[0098] If the substitution temperature calculation coefficients are 0.30, 0.30, 0.25, and 0.15 respectively, then the substitution temperature data are calculated as follows:

[0099]

[0100] The temperature unit in the above calculation is °C, resulting in a substitute temperature data of 6.1395 °C. In actual recording or display, this can be reduced to 0.01 °C according to temperature measurement accuracy requirements, i.e., recorded as 6.14 °C. This substitute temperature data is used to replace the input data from the abnormal temperature sensor channel in reagent site temperature fusion and participates in the generation of equivalent reagent site temperature data.

[0101] like Figure 5 As shown, the zoned temperature control execution component includes a semiconductor refrigeration module, a zoned temperature-conducting duct, a first airflow regulator, a second airflow regulator, and a temperature-conducting opening regulator. The zoned temperature-conducting duct includes at least two box-segment temperature-conducting branches, each corresponding to a first and second box-segment temperature-conducting branch. The first airflow regulator is located in the first box-segment temperature-conducting branch, the second airflow regulator is located in the second box-segment temperature-conducting branch, and the temperature-conducting opening regulator is located in the cross-segment reference temperature-conducting cavity 4. The semiconductor refrigeration module may include a semiconductor refrigeration chip, a heat sink, a cold-end temperature-conducting plate, and a fan. The first and second airflow regulators may be miniature dampers, variable-speed fans, or adjustable guide vanes. The temperature-conducting opening regulator is used to adjust the temperature-conducting opening of the cross-segment reference temperature-conducting cavity 4.

[0102] The edge temperature controller includes a cross-segment equalization control unit. Based on the folding angle data collected by the folding angle sensor 12, the cross-segment reference temperature data collected by the cross-segment reference temperature sensor group, and the equivalent temperature data of the reagent positions within different insulation box segments, the cross-segment equalization control unit generates cooling power control commands, a first airflow control command, a second airflow control command, and a temperature conduction opening control command. The cooling power control command acts on the semiconductor cooling module, the first airflow control command acts on the first airflow regulator, the second airflow control command acts on the second airflow regulator, and the temperature conduction opening control command acts on the temperature conduction opening regulator. In one embodiment, the cross-segment equalization control unit uses temperature deviation, cross-segment reference temperature difference, and folding angle range as inputs to generate the aforementioned execution commands according to preset control rules; wherein, the temperature deviation is calculated from the equivalent temperature data of the reagent positions and the target control temperature, and the cross-segment reference temperature difference is calculated from the calibrated temperature data of the first cross-segment temperature sensor 8 and the second cross-segment temperature sensor 9. The first air volume regulator, the second air volume regulator, and the temperature guide opening regulator can be set with multiple control levels. The cross-segment equalization control unit can increase, decrease, or maintain the corresponding control level according to the temperature deviation and the cross-segment reference temperature difference.

[0103] In one specific embodiment, the average value of the equivalent temperature data of the reagent positions corresponding to the six reagent temperature measuring seats 5 in the first insulated box section 1 is 7.60℃, and the average value of the equivalent temperature data of the reagent positions corresponding to the six reagent temperature measuring seats 5 in the second insulated box section 2 is 5.80℃. The target refrigeration temperature range is 2℃ to 8℃, and the target control temperature is 5.00℃. The edge temperature controller can calculate the temperature deviation of the first box section and the temperature deviation of the second box section as follows:

[0104]

[0105]

[0106] in, This represents the temperature deviation corresponding to the first insulation box segment 1. This refers to the temperature deviation corresponding to the second insulation box segment 2. The temperature unit in the above calculations is °C. Since the temperature deviation corresponding to the first insulation box segment 1 is greater than the temperature deviation corresponding to the second insulation box segment 2, the cross-segment equalization control unit generates a first airflow control command to increase the opening of the first airflow regulator and a second airflow control command to maintain or decrease the opening of the second airflow regulator. Simultaneously, when the cross-segment reference temperature difference between the first cross-segment temperature sensor 8 and the second cross-segment temperature sensor 9 is greater than 0.50 °C and the folding angle data is within the half-folding range, the cross-segment equalization control unit generates a temperature conduction opening control command to increase the opening of the temperature conduction opening regulator. The cooling power control command can be generated based on the larger value between the temperature deviation of the first and second box segments, causing the semiconductor cooling module to increase its cooling power in the current cycle.

[0107] In one embodiment, each reagent temperature measuring seat 5 is assigned a seat number. The temperature control system of the foldable clinical laboratory reagent refrigerator based on an intelligent sensing system also includes a temperature measurement and recording unit. The temperature measurement and recording unit is connected to an edge temperature controller and records the seat number, reagent position equivalent temperature data, folding angle data collected by the folding angle sensor 12, lid status data collected by the lid status sensor 13, cooling power control commands, first airflow control commands, second airflow control commands, and temperature conduction opening control commands to form a temperature measurement record. The temperature measurement record can be stored in local memory or output to a host computer, mobile terminal, or cold chain traceability system via an external communication interface. The temperature measurement record is used to record the reagent placement position, temperature measurement results, refrigerator status, and executed actions.

[0108] To verify the impact of the above-described implementation method on temperature measurement data acquisition, a simulated comparative experiment was conducted. The comparative example adopted a limited temperature feedback method within the folding refrigeration equipment in the background art, i.e., setting a small number of spatial temperature measurement points within the folding refrigeration space and performing overall temperature control based on these spatial temperature measurement points. The embodiment employed the intelligent sensing system, temperature measurement calibration component, folding state compensation unit, lid disturbance screening unit, and reagent temperature fusion unit described in this embodiment. The experimental conditions were: ambient temperature of 25°C, target refrigeration temperature range of 2°C to 8°C, with six simulated reagent containers placed in each insulated box section. Temperature measurement results were tested in the unfolded state, semi-folded state, and after a short period of lid opening. An independent reference thermometer was installed inside each reagent container, and the measurement results of the reference thermometer were used as a comparison benchmark. Recording began after the temperature control system had been running stably for 20 minutes, with a sampling interval of 30 seconds, and continuous sampling for 10 minutes for each test item. The maximum measurement error for reagent placement is the maximum absolute value of the difference between the equivalent temperature data of the reagent position corresponding to each reagent temperature measuring seat 5 within the same test item and the measurement result of the corresponding independent reference thermometer. The maximum temperature difference between adjacent insulation box sections is the maximum absolute value of the difference between the average value of the equivalent temperature data of the reagent position in the first insulation box section 1 and the average value of the equivalent temperature data of the reagent position in the second insulation box section 2.

[0109] Table 1. Results of the Simulation Experiment

[0110]

[0111] Furthermore, to illustrate the temperature recovery after the lid was opened and disturbed, please refer to... Figure 6 . Figure 6 The comparison curves show the change of the highest temperature of the reagent site over time between the comparative example and the embodiment under the conditions of an ambient temperature of 25°C, a target refrigeration temperature range of 2°C to 8°C, and the lid being opened for 30 seconds and then closed again. Figure 6 In the comparative test, a limited temperature measurement feedback method within the chamber was used, while in the specific test, an intelligent sensing system and reagent equivalent temperature data were used. Under the test conditions, the curve corresponding to the specific test entered the target refrigeration temperature range within a short time.

[0112] Figure 6 The corresponding test data is shown in Table 2 below.

[0113] Table 2 Comparison of the highest temperature of the reagent compartment after the lid is closed.

[0114]

[0115] From Table 1 and Figure 6It can be seen that under the test conditions, in the unfolded state, semi-folded state, and lid-open disturbance state, after the intelligent sensing system collects multiple types of temperature and status data, and the temperature measurement calibration component generates the equivalent temperature data of the reagent position, the temperature measurement error of the reagent placement position is lower than that of the comparative example. Simultaneously, through cross-segment temperature difference compensation, lid disturbance screening, temperature measurement self-calibration, and abnormal channel replacement, temperature measurement data for the corresponding reagent temperature measuring seat 5 can be continuously generated even under conditions of folding state changes, lid disturbance, and abnormal temperature sensor channels. The zoned temperature control execution component controls the cooling power, zoned airflow, and temperature conduction opening based on the reagent position equivalent temperature data, enabling the reagent temperature measuring seat 5 in different insulated box segments to obtain corresponding zoned adjustments.

[0116] In the above embodiments, the core function of the intelligent sensing system is to collect temperature and status data directly related to temperature measurement, including reagent proximity temperature, section wall temperature, cross-section reference temperature, folding angle, and lid status. The core function of the temperature measurement calibration component is to perform consistency calibration, folding status compensation, lid disturbance screening, and reagent position temperature fusion on the above data, thereby generating reagent position equivalent temperature data corresponding to the placement location of each clinical laboratory reagent.

[0117] It should be noted that the embodiments of the present invention have better implementability and are not intended to limit the present invention in any way. Any person skilled in the art may use the above-disclosed technical content to change or modify it into equivalent effective embodiments. However, any modifications or equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention shall still fall within the scope of the technical solution of the present invention.

Claims

1. A temperature control system for a foldable clinical laboratory reagent refrigerator based on an intelligent sensing system, characterized in that, It includes a foldable refrigerated box, a reagent carrier assembly, an intelligent sensing system, a temperature measurement and calibration assembly, a zoned temperature control execution assembly, and an edge temperature control controller; The foldable refrigerator box includes at least two insulated box sections, a foldable temperature-conducting connection assembly connecting adjacent insulated box sections, and a box lid, wherein a cross-segment reference temperature-conducting cavity is formed within the foldable temperature-conducting connection assembly. The reagent carrying components are respectively disposed in each of the insulation box sections, forming multiple reagent temperature measuring seats; The intelligent sensing system includes a reagent proximity temperature sensor group, a box segment wall temperature sensor group, a cross-segment reference temperature sensor group, a folding angle sensor, and a box lid status sensor. The temperature measurement and calibration component generates reagent site equivalent temperature data based on the data collected by the intelligent sensing system. The edge temperature controller controls the partition temperature control execution component based on the reagent position equivalent temperature data.

2. The temperature control system for the foldable clinical laboratory reagent refrigerator based on an intelligent sensing system according to claim 1, characterized in that, The reagent temperature measuring seat includes a bottom temperature-conducting part and a lateral limiting part; the reagent proximity temperature sensor group includes a bottom temperature sensor and a lateral temperature sensor, and each reagent temperature measuring seat is provided with at least one bottom temperature sensor and at least one lateral temperature sensor, the bottom temperature sensor is disposed on the bottom temperature-conducting part, and the lateral temperature sensor is disposed on the lateral limiting part.

3. The temperature control system for the foldable clinical laboratory reagent refrigerator based on an intelligent sensing system according to claim 2, characterized in that, The bottom temperature-conducting part includes a temperature-conducting base, the lateral limiting part includes a lateral temperature-conducting clip, and the reagent temperature measuring seat also includes a sensor isolation groove; the bottom temperature sensor is embedded in the temperature-conducting base, the lateral temperature sensor is embedded in the lateral temperature-conducting clip, and the sensor isolation groove is disposed between two adjacent reagent temperature measuring seats.

4. The temperature control system for the foldable clinical laboratory reagent refrigerator based on an intelligent sensing system according to claim 1, characterized in that, The box section wall temperature sensor group includes an air inlet side wall temperature sensor and a return air side wall temperature sensor; the air inlet side wall temperature sensor is located on the side of the temperature-conducting airflow entering the corresponding heat-insulating box section formed by the partition temperature control execution component, and the return air side wall temperature sensor is located on the side of the temperature-conducting airflow returning the corresponding heat-insulating box section formed by the partition temperature control execution component.

5. The temperature control system for the foldable clinical laboratory reagent refrigerator based on an intelligent sensing system according to claim 1, characterized in that, The temperature measurement calibration component includes a sensor consistency calibration unit, a folding state compensation unit, a lid disturbance screening unit, and a reagent position temperature fusion unit; the sensor consistency calibration unit generates calibrated temperature data based on the original temperature data of the reagent proximity temperature sensor group, the box segment wall temperature sensor group, and the cross-segment reference temperature sensor group. The folding state compensation unit generates a cross-segment temperature difference compensation value based on the folding angle data collected by the folding angle sensor and the data collected by the cross-segment reference temperature sensor group; the lid disturbance screening unit determines the temperature sensor channel participating in temperature fusion based on the lid state data collected by the lid state sensor; the reagent position temperature fusion unit generates the reagent position equivalent temperature data based on the calibrated temperature data, the cross-segment temperature difference compensation value, and the temperature sensor channel participating in temperature fusion.

6. The temperature control system for the foldable clinical laboratory reagent refrigerator based on an intelligent sensing system according to claim 5, characterized in that, The sensor consistency calibration unit generates the calibrated temperature data according to the following formula: in, The first in the intelligent sensing system Temperature data after calibration of each temperature sensor. The first in the intelligent sensing system Raw temperature data from each temperature sensor. The first in the intelligent sensing system Gain calibration coefficients for each temperature sensor The first in the intelligent sensing system Zero-point calibration value of each temperature sensor. Number the temperature sensor.

7. The temperature control system for the foldable clinical laboratory reagent refrigerator based on an intelligent sensing system according to claim 6, characterized in that, The sensor consistency calibration unit is equipped with a reference sampling state table, which includes the lid closing state, folding angle range, and execution state of the partition temperature control execution component. When the lid state data collected by the lid state sensor, the folding angle data collected by the folding angle sensor, and the execution state of the partition temperature control execution component satisfy the reference sampling state table, the sensor consistency calibration unit updates the gain calibration coefficient and the zero-point calibration value of the corresponding temperature sensor according to the calibrated temperature data of the cross-segment reference temperature sensor group.

8. The temperature control system for the foldable clinical laboratory reagent refrigerator based on an intelligent sensing system according to claim 5, characterized in that, The folding state compensation unit is equipped with a folding angle interval table and a cross-segment temperature difference compensation table; the cross-segment reference temperature sensor group includes a first cross-segment temperature sensor and a second cross-segment temperature sensor, the first cross-segment temperature sensor is disposed at one end of the cross-segment reference temperature conducting cavity near one of the insulation box segments, and the second cross-segment temperature sensor is disposed at one end of the cross-segment reference temperature conducting cavity near the other adjacent insulation box segment; the folding state compensation unit determines the folding angle interval according to the folding angle interval table, and determines the cross-segment temperature difference compensation value according to the calibrated temperature data of the first cross-segment temperature sensor and the second cross-segment temperature sensor.

9. The temperature control system for the foldable clinical laboratory reagent refrigerator based on an intelligent sensing system according to claim 8, characterized in that, The lid disturbance screening unit is equipped with an opening time counter and a disturbance channel marking table. When the lid status sensor detects that the lid is open, the lid disturbance screening unit generates opening duration data based on the opening time counter, and determines the temperature sensor channel participating in temperature fusion based on the opening duration data, the folding angle range, and the disturbance channel marking table.

10. The temperature control system for the foldable clinical laboratory reagent refrigerator based on an intelligent sensing system according to claim 5, characterized in that, It also includes a temperature measurement self-calibration component; the temperature measurement self-calibration component includes a standard thermal pulse element and a sensor response determination unit. The standard thermal pulse element is disposed in the cross-segment reference temperature conduction cavity. The sensor response determination unit is connected to the cross-segment reference temperature sensor group and the edge temperature controller respectively. The sensor response determination unit generates a channel validity mark based on the temperature change data before and after the standard thermal pulse element is activated.

Citation Information

Patent Citations

  • Folding refrigerator for field operations

    CN201662293U