Skin care composition comprising glycerin

Abstract

Skin care compositions suitable for moisturizing the skin are provided, and in particular, compositions comprising relatively high levels of glycerin are provided. Exemplary skin care compositions can comprise: a. greater than 40% of one or more humectants, by total weight of the composition; b. a mixture of glycerides; c. one or more emollients; d. one or more skin conditioning agents; and e. water.

Description

Technical Field

[0001] This invention relates to compositions suitable for moisturizing the skin. More specifically, this invention relates to compositions comprising a relatively high level of humectant. Background Technology

[0002] Moisturizers are mixtures of chemical agents specifically designed to soften the outer layer of skin or hair. Personal care compositions with moisturizing properties are known. Consumers expect such compositions to meet a range of requirements. In addition to determining the intended skin / hair care effect, values ​​are set for various parameters such as dermatological compatibility, appearance, sensory impression, storage stability, and ease of use. For example, glycerin is a humectant.

[0003] To reduce the amount of water lost to the external environment, traditional practices involve applying a residual film of a composition containing an occlusive agent or a humectant to the skin surface. Occlusive agents leave a residual film that acts as a mechanical barrier, preventing water from evaporating from the stratum corneum and penetrating the skin from the external environment. Humectants, however, are hygroscopic materials that act like a sponge, retaining water near the skin and allowing for a higher level of hydration to be maintained within the stratum corneum.

[0004] Many humectants have been proposed for use in various skincare products in the past. Glycerin is a known humectant. However, higher concentrations of glycerin are known to provide undesirable sensory properties (e.g., too sticky) and can be difficult to formulate.

[0005] Therefore, there is a continuous need for skincare compositions that provide both moisturizing effects and maintain other desired properties. Summary of the Invention

[0006] One aspect of the present invention relates to a skin care composition comprising:

[0007] a. One or more wetting agents, accounting for more than 40% by total weight of the composition;

[0008] b. A mixture of glycerides;

[0009] c. One or more emollients;

[0010] d. One or more skin conditioning agents; and

[0011] e. Water.

[0012] In one or more embodiments, the composition is substantially free of isocetyl alcohol. In some embodiments, the humectant includes glycerin. In one or more embodiments, glycerin is present in an amount of about 41% to about 50% by weight of the total weight of the composition. In some embodiments, one or more glycerides include triglycerides. In one or more embodiments, one or more triglycerides include caprylic / capric triglycerides. In some embodiments, one or more glycerides are present in an amount of about 1% to about 12% by weight. In one or more embodiments, one or more emollients are present in an amount of about 1% to about 10% by weight. In some embodiments, one or more emollients are selected from the group consisting of: C12-C15 alkylbenzoates; cyclodimethylsiloxanes, polydimethylsiloxanes, and mixtures thereof. In one or more embodiments, one or more emollients include polydimethylsiloxanes. In some embodiments, one or more skin conditioning agents are selected from the group consisting of: glycols, cationic surfactants, and combinations thereof. In one or more embodiments, one or more skin conditioning agents include caprylyl glycol. In some embodiments, the composition also contains processed oat ingredients. In one or more embodiments, water is present in an amount of less than about 30% by weight based on the total weight of the composition.

[0013] Another aspect of the invention relates to a method of moisturizing the skin, the method comprising applying to the skin any of the skin care compositions described herein.

[0014] Another aspect of the present invention relates to a skin care composition comprising:

[0015] a. More than about 40% by weight of glycerol based on the total weight of the composition;

[0016] b. Caprylic / capric triglycerides, about 1% to about 10% by weight of the total weight of the composition;

[0017] c. about 1% to about 10% by weight of polydimethylsiloxane based on the total weight of the composition;

[0018] d. Octyl glycol, about 0.01% to about 3% by weight of the total weight of the composition;

[0019] e. From about 0.01% to about 3% by weight of the processed oat component, based on the total weight of the composition; and

[0020] f. Approximately 25% by weight to approximately 35% by weight of water.

[0021] In one or more embodiments, water is present in an amount of about 25% to about 32% by weight. In some embodiments, glycerol is present in an amount of about 42% to about 50% by weight. In one or more embodiments, the composition further comprises one or more adjuvants selected from the group consisting of rheology modifiers, emulsifiers, preservatives, fragrances, and combinations thereof.

[0022] These and other features and advantages of the invention will become apparent from the following detailed description of the invention. Detailed Implementation

[0023] As used in this article, “cosmetically / dermatologically acceptable” means suitable for use in contact with tissues (e.g., skin or hair) without undue toxicity, incompatibility, instability, irritation and / or allergic response, etc.

[0024] As used herein, the term "safe and effective amount" means an amount sufficient to produce the desired effect but low enough to avoid serious side effects. The safe and effective amount of a compound, extract, or composition will vary depending on factors such as the end-user's age, health and environmental exposure, the duration and nature of the treatment, the specific extract, ingredient, or composition used, and the specific pharmaceutically acceptable carrier used.

[0025] As used herein, “substantially contains” or “essentially contains no” means that the ingredient contains less than 0.1% by weight or less than 0.01% by weight, or contains no ingredient.

[0026] To provide a more concise description, some of the quantitative expressions given herein are not modified by the term "approximately". It should be understood that, whether or not the term "approximately" is explicitly used, each quantity given herein is intended to refer to an actual given value, and also to an approximation of such given values ​​that can be reasonably inferred by one of ordinary skill in the art, including approximations of such given values ​​caused by experimental and / or measurement conditions.

[0027] To provide a more concise description, some quantitative expressions in this document are described as a range from approximately X to approximately Y. It should be understood that when describing a range, the range is not limited to the upper and lower limits stated, but should include the entire range of approximately X to approximately Y, or any quantity or range therein.

[0028] Therefore, one aspect of the present invention relates to a skin care composition comprising:

[0029] a. One or more wetting agents, accounting for more than 40% by total weight of the composition;

[0030] b. A mixture of glycerides;

[0031] c. One or more emollients;

[0032] d. One or more skin conditioning agents; and

[0033] e. Water.

[0034] Surprisingly, such compositions are found to be microbiologically stable while still providing relatively high levels of wetting agents, particularly glycerin.

[0035] wetting agent

[0036] Any of a variety of commercially available humectants capable of providing moisturizing properties to personal care compositions is suitable for this invention. Examples of suitable humectants, non-exclusively, include: 1) water-soluble liquid polyols selected from the group consisting of glycerin, propylene glycol, hexanediol, butylene glycol, and dipropylene glycol. In a specific embodiment, the humectant includes glycerin.

[0037] The compositions described herein advantageously contain relatively high levels of glycerol. In one or more embodiments, glycerol is present in an amount greater than about 41% by weight of the total composition. In some embodiments, glycerol is present in an amount ranging from about 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%, 49%, or 50% by weight of the total composition to about 50%, 51%, 52%, 53%, 54%, 55%, or 60% by weight.

[0038] Glycerides

[0039] The compositions described herein may comprise one or more glycerides, particularly triglycerides. In another embodiment, one or more triglycerides include caprylic / capric triglycerides.

[0040] One or more glycerides may be present in amounts from about 0.5% by weight, 1% by weight, 2% by weight, 3% by weight, 4% by weight, 5% by weight, 6% by weight, or 7% by weight to about 7% by weight, 8% by weight, 9% by weight, 10% by weight, 11% by weight, or 12% by weight, based on the total weight of the composition. In another embodiment, one or more glycerides (e.g., caprylic / capric triglycerides) are present in amounts from about 5% by weight to about 9% by weight or about 7% by weight, based on the total weight of the composition.

[0041] While not wishing to be bound by any particular theory, it is believed that the presence of glycerides (e.g., caprylic / capric triglycerides) prevents the growth of unwanted pathogens. Specifically, although isocetyl has been previously used in similar compositions, the challenge lies in its high glycerol content (and therefore relatively low aqueous phase). When isocetyl is present, the preservative is thought to preferentially leave the aqueous phase and enter the oil phase, exposing the aqueous phase and causing various microbiological tests to fail. With the addition of one or more glycerides (e.g., caprylic / capric triglycerides), the growth of unwanted pathogens is not observed in the composition. Therefore, in one or more embodiments, the composition is substantially free of isocetyl.

[0042] Moisturizer

[0043] Emollients are compounds that help maintain the soft, smooth, and supple appearance of the skin (e.g., by remaining on the skin's surface or in the stratum corneum to act as a lubricant). Examples of suitable emollients include those found in Chapter 35, pages 399-415 (G Zocchi's Skin FeelAgent), of the Handbook of Cosmetic Science and Technology (edited by A. Barel, M. Paye, and H. Maibach, published by Marcel Dekker, Inc. (New York, NY) 2001), and include, but are not limited to, polydimethylsiloxane, petrolatum, hexyldecyl stearate, glyceryl oleate, and plant, nut, and vegetable oils such as macadamia oil, rice bran oil, grapeseed oil, palm oil, evening primrose oil, hydrogenated peanut oil, and avocado oil.

[0044] In one or more embodiments, the emollient comprises one or more emollients selected from the group consisting of: C12-C15 alkylbenzoates; cyclodimethylsiloxanes, polydimethylsiloxanes, and mixtures thereof. In another embodiment, the emollient comprises polydimethylsiloxane.

[0045] One or more emollients may be present in amounts from about 0.5% by weight, 1% by weight, 2% by weight, 3% by weight, 4% by weight, 5% by weight, 6% by weight, 7% by weight, 8% by weight, 9% by weight or 10% by weight to about 2% by weight, 3% by weight, 4% by weight, 5% by weight, 6% by weight, 7% by weight, 8% by weight, 9% by weight, 10% by weight, 11% by weight or 15% by weight, based on the total weight of the composition.

[0046] Skin conditioning agent

[0047] The compositions described herein may comprise one or more ingredients that provide conditioning effects to the skin. In one or more embodiments, one or more skin conditioning agents are selected from the group consisting of glycols, cationic surfactants, and combinations thereof. In another embodiment, one or more skin conditioning agents include caprylyl glycol.

[0048] Processed oat ingredients

[0049] As used herein, the term "processed oat ingredient" refers to an ingredient typically derived from a portion of the oat plant (oats). This ingredient can be a product of processing (e.g., extraction, milling, fermentation) of one or more parts of the oat plant (e.g., grains, leaves, stems, seeds), or a molecule found in the oat plant (e.g., beta-glucan, flavonoids, ammonia, lipids, peptides, etc.). This definition is intended to encompass processed oat ingredients derived from sources other than oats (e.g., from another plant or chemically synthesized) but otherwise related to oats. In one or more embodiments, the processed oat ingredient is selected from oat extracts, colloidal oat flour, oat flour, oat bran, oat protein, oat peptides, oat oil, fermented oats, ammonia, beta-glucan, modified oat grain materials (e.g., chemically modified, enzymatically modified, microbially modified), and combinations thereof. As used herein, "colloidal oat flour" refers to a powder obtained from the milling and further processing of whole oat grains that conforms to the U.S. Oat No. 1 or No. 2 standard. Colloidal oat flour has the following particle size distribution: no more than 3% of the total particles have a particle size greater than 150 micrometers, and no more than 20% of the total particles have a particle size greater than 75 micrometers. Examples of suitable colloidal oat flour include, but are not limited to, “Tech-0” from Beacon Corporation and colloidal oat flour from Quaker. In one or more embodiments, the processed oat ingredient includes oat extract, colloidal oat flour, and oat oil. In some embodiments, the processed oat ingredient includes oat extract. In one or more embodiments, the processed oat ingredient includes colloidal oat flour. In some embodiments, the processed oat ingredient includes oat oil. In some embodiments, the processed oat ingredient is selected from oat extract, colloidal oat flour, oat oil, and combinations thereof. In some embodiments, the processed oat ingredient includes oat extract, colloidal oat flour, and oat oil. In one or more embodiments, the processed oat ingredient includes ammonia. In some embodiments, the processed oat ingredient includes fermented oats. In one or more embodiments, the processed oat component includes β-glucan.

[0050] The processed oat ingredient may be present in amounts ranging from about 0.01% by weight, 0.05% by weight, 0.1% by weight, 0.2% by weight, 0.3% by weight, 0.4% by weight, 0.5% by weight, 0.6% by weight, 0.7% by weight, 0.8% by weight, 0.9% by weight, 1.0% by weight, 1.5% by weight, 2% by weight, 2.5% by weight, 3% by weight, 3.5% by weight, 4% by weight, 4.5% by weight, or 5% by weight to about 5% by weight, 5.5% by weight, 6% by weight, 6.5% by weight, 7% by weight, 8% by weight, 9% by weight, 10% by weight, 11% by weight, 12% by weight, 15% by weight, 20% by weight, 25% by weight, or 30% by weight of the total composition. In one or more embodiments, the processed oat ingredient is present in amounts ranging from about 0.1% by weight to about 10% by weight of the total composition. In some embodiments, the processed oat ingredient is present in amounts ranging from about 0.1% by weight to about 5% by weight of the total composition. In one or more embodiments, the processed oat ingredient is present in an amount ranging from about 0.5% by weight to about 5% by weight based on the total weight of the composition. In some embodiments, the processed oat ingredient is present in an amount ranging from about 0.5% by weight to about 4% by weight based on the total weight of the composition. In one or more embodiments, the processed oat ingredient is present in an amount ranging from about 0.5% by weight to about 3% by weight based on the total weight of the composition. In some embodiments, the processed oat ingredient is present in an amount ranging from about 1% by weight to about 3% by weight based on the total weight of the composition. In one or more embodiments, the processed oat ingredient is present in an amount ranging from about 1% by weight to about 2% by weight based on the total weight of the composition. In some embodiments, the processed oat ingredient is present in an amount of about 1% by weight based on the total weight of the composition. In one or more embodiments, the processed oat ingredient is present in an amount of about 2% by weight based on the total weight of the composition.

[0051] In one or more embodiments, the processed oat component comprises colloidal oat flour, and the colloidal oat flour is present in an amount of about 0.5% by weight to about 3% by weight based on the total weight of the composition. In some embodiments, the colloidal oat flour is present in an amount of about 1% by weight to about 3% by weight based on the total weight of the composition. In one or more embodiments, the colloidal oat flour is present in an amount of about 1% by weight based on the total weight of the composition. In one or more embodiments, the colloidal oat flour is present in an amount of about 2% by weight based on the total weight of the composition.

[0052] In some embodiments, the processed oat component includes oat extract, colloidal oat flour, and oat oil, and the total amount of these three components may be present in amounts ranging from about 0.01% by weight, 0.05% by weight, 0.1% by weight, 0.2% by weight, 0.3% by weight, 0.4% by weight, 0.5% by weight, 0.6% by weight, 0.7% by weight, 0.8% by weight, 0.9% by weight, 1.0% by weight, 1.5% by weight, 2% by weight, 2.5% by weight, 3% by weight, 3.5% by weight, 4% by weight, 4.5% by weight, or 5% by weight to about 5% by weight, 5.5% by weight, 6% by weight, 6.5% by weight, 7% by weight, 8% by weight, 9% by weight, 10% by weight, 11% by weight, 12% by weight, 15% by weight, 20% by weight, 25% by weight, or 30% by weight of the total composition. In one or more embodiments, the total amount of oat extract, colloidal oat flour, and oat oil is present in amounts ranging from about 0.1% by weight to about 10% by weight based on the total weight of the composition. In some embodiments, the total amount of oat extract, colloidal oat flour, and oat oil is present in an amount ranging from about 0.1% by weight to about 5% by weight based on the total weight of the composition. In one or more embodiments, the total amount of oat extract, colloidal oat flour, and oat oil is present in an amount ranging from about 0.5% by weight to about 5% by weight based on the total weight of the composition. In some embodiments, the total amount of oat extract, colloidal oat flour, and oat oil is present in an amount ranging from about 0.5% by weight to about 4% by weight based on the total weight of the composition.

[0053] Other ingredients

[0054] The cleaning compositions described herein contain water as a cosmetically acceptable carrier. As used herein, the term "cosmetically acceptable" means that the carrier is suitable for use in contact with the skin without causing undue toxicity, incompatibility, instability, irritation, allergic response, etc. Water may be present in an amount ranging from about 10%, 15%, 20%, 25%, or 30% by weight of the total composition to about 20%, 25%, 30%, 35%, or 40% by weight. In some embodiments, water is present in an amount ranging from about 20% to 30% by weight, or from about 23% to about 28% by weight of the total composition.

[0055] The compositions of the present invention may comprise any of a variety of additional auxiliary ingredients conventionally used in health care / personal care compositions (generally referred to as "personal care components"). These additional personal care components non-exclusively include one or more pearlescent or opaque agents, thickeners, secondary conditioning agents, chelating agents, active substances, exfoliating agents, and additives that enhance the appearance, feel, and aroma of the composition, such as colorants, fragrances, preservatives, pH adjusters, rheology modifiers, etc. Such auxiliary ingredients (when present) will be cosmetically / dermatologically acceptable and are present in safe and effective amounts. In one or more embodiments, the compositions of the present invention further comprise one or more auxiliary agents selected from the group consisting of rheology modifiers, emulsifiers, preservatives, fragrances, and combinations thereof.

[0056] Surfactants are defined as surfactants intended for cleaning or emulsification. Examples of suitable surfactants include those found in Chapter 37, pages 431-450 (L. Oldenhove de Guertechin's Classification of Surfactants) of the Handbook of Cosmetic Science and Technology (edited by A. Barel, M. Paye, and H. Maibach, published by Marcel Dekker, Inc. (New York, NY) in 2001), and include, but are not limited to, anionic surfactants, amphoteric surfactants, nonionic surfactants, and cationic surfactants. Furthermore, one of the advantages of this invention is CAPB's ability to achieve excellent foaming properties without the need for additional anionic surfactants, particularly in some embodiments where the cleaning composition is substantially free of or contains no anionic surfactants. As used herein, the term "anionic surfactant" refers to a surfactant having a negatively charged hydrophilic polar group. Examples of anionic surfactants include ammonium lauryl sulfate, sodium lauryl polyoxyethylene ether sulfate, sodium lauryl sarcosinate, sodium myristyl polyoxyethylene ether sulfate, sodium alkyl polyoxyethylene ether sulfate, sodium stearate, sodium lauryl sulfate, α-olefin sulfonate, and ammonium lauryl polyoxyethylene ether sulfate. In another embodiment, the cleaning composition is substantially free of or contains no sodium lauryl ether sulfate.

[0057] Examples of suitable nonionic surfactants include, but are not limited to, fatty alcohols or amide ethoxylates, monoglyceride ethoxylates, sorbitol ester ethoxylates, alkyl polyglycosides, and mixtures thereof. A suitable nonionic surfactant is a polyoxyethylene derivative of a polyol ester, wherein the polyoxyethylene derivative of the polyol ester (1) is derived from (a) a fatty acid containing about 8 to about 22, and preferably about 10 to about 14 carbon atoms, and (b) a polyol selected from sorbitol, sorbitol, glucose, α-methylglucoside, polydextrose having an average of about 1 to about 3 glucose residues per molecule, glycerol, pentaerythritol, and mixtures thereof; (2) contains an average of about 10 to about 120, and preferably about 20 to about 80 oxyethylene units; and (3) has an average of about 1 to about 3 fatty acid residues per mole of the polyoxyethylene derivative of the polyol ester.

[0058] Examples of polyoxyethylene derivatives of polyol esters include, but are not limited to, PEG-80, sorbitan laurate, and polysorbate 20. PEG-80 sorbitan laurate (a sorbitan laurate monoester perethoxylated with an average of about 80 moles of ethylene oxide) is available under the trade name “Atlas G-4280” from ICI Surfactants, Wilmington, Del., WA. Polysorbate 20 (a laurate monoester of a mixture of sorbitol and sorbitan anhydride condensed with about 20 moles of ethylene oxide) is available under the trade name “Tween 20” from ICI Surfactants, Wilmington, Del., WA.

[0059] Another class of suitable nonionic surfactants includes long-chain alkyl glucosides or polyglucosides, which are condensation products of (a) a long-chain alcohol containing about 6 to about 22, and preferably about 8 to about 14 carbon atoms, and (b) glucose or a glucose-containing polymer. Each molecule of alkyl glucoside has about 1 to about 6 glucose residues. A preferred glucoside is decyl glucoside, which is a condensation product of decanol and a glucose polymer and is commercially available under the trade name “Plantaren 2000” from Henkel Corporation, Hoboken, NJ.

[0060] In some embodiments, the nonionic surfactant is selected from the group consisting of alkyl glucosides (e.g., decyl glucoside, lauryl glucoside, cocoyl glucoside), PEG-80, sorbitol laurate, and combinations thereof.

[0061] The compositions of the present invention may also contain amphoteric surfactants. As used herein, the term "amphoteric" means: 1) a molecule containing both acidic and basic sites, such as, for example, an amino acid containing both amino (basic) and acid (e.g., carboxylic acid, acidic) functional groups; or 2) an amphoteric molecule possessing both positive and negative charges within the same molecule. The latter's charge may depend on or be independent of the pH of the composition. The amphoteric surfactants disclosed herein do not contain counterions. Those skilled in the art will readily recognize that, under the pH conditions of the compositions of the present invention, amphoteric surfactants are electrically neutral due to having a balanced positive and negative charge, or they have counterions such as alkali metal counterions, alkaline earth counterions, or ammonium counterions. Examples of amphoteric surfactants suitable for use in this invention include, but are not limited to, amphoteric carboxylates such as alkyl amphoteric acetates (mono or di); alkyl betaines; alkylamide alkyl betaines (other than CAPB); alkylamide alkyl sulfobetaine; alkyl amphoteric phosphates; phosphorylated imidazolines such as phosphate betaine and pyrophosphate betaine; carboxyalkyl alkyl polyamines; alkyl imino dipropionates; alkyl amphoteric glycinates (mono or di); alkyl amphoteric propionates (mono or di); N-alkyl β-aminopropionic acid; alkyl polyaminocarboxylates; and mixtures thereof.

[0062] The cationic surfactants suitable for use in this invention include alkyl quaternary ammonium salts (monoalkyl, dialkyl, or trialkyl quaternary ammonium salts), benzyl quaternary ammonium salts, ester quaternary ammonium salts, ethoxylated quaternary ammonium salts, alkylamines, and mixtures thereof, wherein the alkyl group has about 6 to about 30 carbon atoms, preferably about 8 to 22 carbon atoms. These cationic surfactants may be used in the compositions of this invention in amounts of about 0.01% to about 20%, about 0.05% to about 15%, or about 0.1% to about 10% based on the total weight of the composition.

[0063] Any of a variety of commercially available pearlescent or opaque agents is suitable for use in this invention. These pearlescent or opaque agents are capable of suspending water-insoluble additives (such as siloxanes) and / or tend to indicate to consumers that the resulting product is a conditioning shampoo. If used, the pearlescent or opaque agent may be present in an amount of about 0.1% to about 10% (e.g., about 1.5% to about 7% or about 2% to about 5%) based on the total weight of the composition. Examples of suitable pearlescent or opaque agents include, but are not limited to, the following: (a) a fatty acid having about 16 to about 22 carbon atoms and (b) a monoester or diester of ethylene glycol or propylene glycol; (a) a fatty acid having about 16 to about 22 carbon atoms and (b) a product of the formula: HO-(JO). a—H is a monoester or diester of a polyalkylene glycol, wherein J is an alkylene group having about 2 to about 3 carbon atoms, and a is 2 or 3; a fatty alcohol containing about 16 to about 22 carbon atoms; a fatty acid ester of the formula: KCOOCH2L, wherein K and L independently contain about 15 to about 21 carbon atoms; an inorganic solid insoluble in the composition; and mixtures thereof.

[0064] The described composition may also contain any of a variety of conventional thickeners. Examples of suitable conventional thickeners include a variety of thickeners having a molecular weight greater than about 100,000 g / mol, including chemicals such as: hydroxyalkyl cellulose; alkyl cellulose; hydroxyalkylalkyl cellulose; xanthan gum and guar gum, succinyl polysaccharide gum; acrylate / C10-30 alkyl acrylate crosspolymers; and mixtures thereof.

[0065] Examples of suitable thickeners, non-exclusively, include: 1) Formula: HO-(CH2CH2O) z H) a monoester or diester of polyethylene glycol, wherein z is an integer from about 3 to about 200; and 2) a fatty acid containing about 16 to about 22 carbon atoms; fatty acid esters of ethoxylated polyols; ethoxylated derivatives of monoesters and diesters of fatty acids and glycerol; hydroxyalkyl cellulose; alkyl cellulose; hydroxyalkylalkyl cellulose; hydrophobically modified alkali-swellable emulsions (HASE); hydrophobically modified ethoxylated polyurethanes (HEUR); xanthan gum and guar gum; and mixtures thereof. Thickeners include polyethylene glycol esters, such as PEG-150 distearate, which is available under the trade name “PEG 6000 DS” from Hallstar Company (Chicago, Ill.).

[0066] Examples of suitable chelating agents include those capable of protecting and retaining the compositions of the present invention. Chelating agents may include ethylenediaminetetraacetic acid (“EDTA”), such as tetrasodium EDTA, which may be available under the trade name “Versene 100XL” from Dow Chemical Company, Midland, Michigan, and is present in an amount of about 0% (if not used) to about 0.5% or about 0.05% to about 0.25% based on the total weight of the composition.

[0067] Suitable preservatives include, for example, parabens, quaternary ammonium compounds, phenoxyethanol, benzoates, DMDM ​​hydantoin, and are present in the composition in an amount of about 0% (if not used) to about 1%, or about 0.05% to about 0.5%, based on the total weight of the composition.

[0068] Any fragrance composition suitable for use on the skin can be used in the composition according to the invention.

[0069] The composition may optionally contain one or more beneficial agents or pharmaceutically acceptable salts thereof. As used herein, the term "beneficial agent" encompasses any active ingredient, such as a cosmetic agent or pharmaceutical reagent, that will be delivered to the skin, hair, or fingernails / toenails and / or a desired location thereon. "Cosmetic agent" means any ingredient suitable for cosmetic treatment, providing nutrients, and / or conditioning hair, fingernails / toenails, and / or skin via topical application. "Pharmaceutical reagent" means any drug that is inherently hydrophobic or hydrophilic and suitable for topical application. As used herein, "pharmaceutical agent" includes those agents capable of promoting recovery from injury and disease. One or more beneficial agents (if used) may be contained in any of the first oil phase, second oil phase, or aqueous phase, if compatible with the other components in the selected phase.

[0070] Beneficial agents available herein can be classified according to their therapeutic benefits or their assumed modes of action. However, it should be understood that in some cases, beneficial agents available herein may provide more than one therapeutic benefit or act via more than one mode of action. Therefore, for convenience, specific classifications are provided herein, but it is not intended to limit beneficial agents to one or more specific applications listed. Furthermore, compounds identified below as suitable as beneficial agents may be used in amounts exceeding or greater than those used for other purposes in cleaning compositions or personal care systems.

[0071] Examples of suitable beneficial agents include, but are not limited to: decolorizing agents; reflective agents; film-forming polymers; additional humectants; amino acids and their derivatives; antimicrobial agents; allergy inhibitors; anti-acne agents; anti-aging agents; anti-wrinkle agents; antiseptics; analgesics; antitussives; antipruritics; local anesthetics; anti-hair loss agents; hair growth promoters; hair growth inhibitors; antihistamines, such as Mandragora Vernalis and Tanacetum Parthenium; anti-infective agents, such as Acacia Catechu, Aloe Barbadensis, Convallaria Majalis, Echinacea, Eucalyptus, Mentha Piperita, Rosa Canina, and Sassafras. Albidum, etc.; anti-inflammatory agents; antiemetics; anticholinergics; vasoconstrictors; vasodilators; wound healing promoters; peptides, polypeptides, and proteins; deodorants and antiperspirants; pharmaceuticals; as well as skin moisturizers; skin firming agents, vitamins; tanning agents; skin brightening agents; antifungal agents, such as cornflower (Centaurea Cyanus) and mountain laurel (Kalmia). Latifolia and antifungal agents for foot preparations; depilatory agents; shaving preparations; topical analgesics; fragrances; antiirritants; hemorrhoid agents; insecticides; poison ivy products; poison oak products; burn products; antidiarrheal agents; prickly heat agents; vitamins; amino acids and their derivatives; herbal extracts; visual pigments; flavonoids; sensory agents; antioxidants; skin conditioning agents; hair brighteners; chelating agents; cell turnover enhancers; colorants; sunscreens, those active ingredients disclosed in U.S. Patent 6,063,397 (which is incorporated herein by reference); antiedema agents; collagen enhancers; and mixtures thereof.

[0072] Examples of suitable anti-edema agents include, non-exclusively, natural bisabolol, synthetic bisabolol, and mixtures thereof.

[0073] Examples of suitable vasoconstrictors, non-exclusively, include horse chestnut extract, Sichuan pepper, and mixtures thereof.

[0074] Examples of suitable anti-inflammatory agents, non-exclusively, include benzoxanol, centella asiatica, bisabolol, chamomile (whole plant), chamomile (without chamomile lactone), green tea extract, green tea concentrate, hydrogen peroxide, lycopene (including “Lyc-o-Pen” purchased from LycoRed Natural Products Industries, Ltd.), chamomile, and mixtures thereof.

[0075] Examples of collagen enhancers include, but are not exclusive to, vitamin A, vitamin C, and mixtures thereof.

[0076] Examples of suitable skin tightening agents include, non-exclusively, dimethylaminoethanol (“DMAE”).

[0077] Examples of suitable reflective agents, non-exclusively, include mica, alumina, calcium silicate, ethylene glycol dioleate, ethylene glycol distearate, silica, sodium magnesium fluorosilicate, and mixtures thereof.

[0078] Suitable film-forming polymers include acetyltyrosine amide, zinc pyrithione, coal tar, benzoyl peroxide, selenium sulfide, hydrocortisone, sulfur, menthol, promocaine hydrochloride, tricetylmethylammonium chloride, polyquaternium 10, panthenol, panthenol triacetate, vitamin A and its derivatives, vitamin B and its derivatives, vitamin C and its derivatives, vitamin D and its derivatives, vitamin E and its derivatives, vitamin K and its derivatives, keratin, lysine, arginine, hydrolyzed wheat protein, hydrolyzed silk protein, octyl methoxycinnamate, oxybenzone, minoxidil, titanium dioxide, zinc dioxide, retinol, erythromycin, retinoic acid, and mixtures thereof.

[0079] One class of beneficial agents includes those therapeutic components that are effective in treating dandruff, seborrheic dermatitis, and psoriasis, as well as related symptoms. Examples of suitable beneficial agents of this class, non-exclusively, include zinc pyrithione, anthralin, shale oil and its derivatives, such as sulfonated shale oil, selenium sulfide, sulfur; salicylic acid; coal tar; povidone-iodine; imidazoles such as ketoconazole; dichlorophenyl imidazolodioxalan (which may be marketed under the name "Elubiol" from Janssen Pharmaceutica, ... (commercially available from NV), clotrimazole, itraconazole, miconazole, imidacloprid, tiaconazole, thioconazole, butoconazole, fluconazole, miconazole nitrate and any possible stereoisomers and derivatives thereof; pyridone ethanolamine salts (hydroxymethyloctanopyrone); selenium sulfide; ciclopirox olamine; anti-psoriasis agents, such as vitamin D analogs (e.g., calcipotriol, calcitriol and tacaleitrol); vitamin A analogs, such as vitamin A esters (e.g., vitamin A palmitate, retinoids, retinol and retinoic acid); corticosteroids, such as hydrocortisone, flubendione, butyrate, clobetasol propionate and mixtures thereof.

[0080] Exemplary Implementation

[0081] The above ingredients can be combined in any combination according to the provided guidelines. For example, in one or more embodiments, the skincare composition comprises:

[0082] a. More than approximately 40% by weight of glycerol;

[0083] b. Approximately 1% to approximately 10% by weight of caprylic / capric triglycerides;

[0084] c. about 1% to about 10% by weight of polydimethylsiloxane;

[0085] d. Approximately 0.01% by weight to approximately 3% by weight of octyl glycol;

[0086] e. Approximately 0.01% to approximately 3% by weight of processed oat ingredients; and

[0087] f. Water.

[0088] In one or more embodiments, water is present in an amount of about 25% to about 36% by weight. In another embodiment, glycerol is present in an amount of about 42% to about 50% by weight.

[0089] method

[0090] This invention provides methods for treating the human body, methods comprising contacting at least a portion of the body with the compositions of this invention. Therefore, another aspect of the invention relates to a method for moisturizing the skin, comprising applying any of the skincare compositions described herein to the skin.

[0091] Any suitable method may be used to apply the composition topically to the skin in need. As used herein, “topical application” means applying or rubbing the composition directly onto the outer layer of skin by hand or with an applicator such as a wipe, roller, or sprayer. For example, the composition may be applied to the skin in need by hand, directly from the packaging, or transferred from a substrate such as a wipe or mask, or a combination of two or more of these. In other embodiments, the composition may be applied via an infusion, tube, roller, sprayer, or added to a bath or otherwise added to water for application to the skin. Such topical application may be directed to any skin on the body that requires treatment, such as the skin of the face, lips, neck, chest, back, buttocks, arms, armpits, and / or legs.

[0092] While the foregoing description illustrates exemplary embodiments of the invention, it should be understood that various additions, modifications, and substitutions can be made to the invention without departing from its spirit and scope. Specifically, those skilled in the art should understand that the invention can be implemented in other specific forms, structures, arrangements, proportions, and with other elements, materials, and components without departing from its spirit or essential characteristics. Those skilled in the art should understand that the invention can be used with many modifications to the structures, arrangements, proportions, materials, and components used in the practice of the invention, modifications that are particularly adaptable to specific environments and operational requirements without departing from the principles of the invention. Therefore, the currently disclosed embodiments are considered illustrative rather than restrictive in all respects, and the scope of the invention is indicated by the appended claims and is not limited by the foregoing description. It should be understood that in the claims, the term "comprising / including" does not exclude other elements or steps. Furthermore, singular references do not exclude plurals. The terms "a," "an," "first," "second," etc., do not exclude plurals.

[0093] Unless otherwise specified, all percentages, parts, and ratios are based on the total weight of the compositions of the present invention. Unless otherwise specified, all such weights relating to the listed ingredients are based on the level of the specific ingredient and therefore do not include carriers or byproducts that may be contained in commercially available materials.

[0094] Example

[0095] Example 1: Preparation method of the composition

[0096] The formulation was prepared using the ingredients listed in Tables 1 and 2. Water was added to the master container, mixing was initiated, and the mixture was heated to 80°C. Glycerin and oat flour were added, and the mixture was continuously mixed and heated until homogeneous. At approximately 70°C–72°C, caprylyl glycol was added, followed by the preservative (for those samples containing it), palmitic acid, stearic acid, cetearyl alcohol, sodium cetearyl sulfate, isocetyl alcohol (for those samples containing it) or caprylic / capric triglyceride (for those samples containing it), and polydimethylsiloxane. Mixing and heating continued until homogeneous. The mixture was homogenized at 72°C for 15 minutes. The mixture was then allowed to begin cooling. At approximately 40°C, ethylhexylglycerin was added, and once homogeneous, oat oil, oat extract, and panthenol (for those samples containing it) were added, and the mixture was mixed again until homogeneous. The pH of Examples 2 and 3 was adjusted to approximately 5.

[0097] Table 1: Compositions of the present invention

[0098]

[0099] Table 2: Comparative Compositions

[0100]

[0101] Example 2: Antimicrobial efficacy test

[0102] The unaged composition prepared in Example 1 was tested for antimicrobial efficacy after preparation. This process was performed using aseptic techniques.

[0103] Prepare the challenge inoculum so that the final inoculum level is 1 x 10⁻¹⁰ per gram of composition. 5 CFU / mL to 1x10 6 CFU / mL, preferably 5 x 10 CFU / mL per gram of composition. 5 CFU / mL to 1x10 6 CFU / mL. Inoculate the following organisms individually or in a bacterial pool.

[0104] Escherichia coli (E. coli) ATCC#8739

[0105] Staphylococcus aureus (S. aureus) ATCC# 6538

[0106] Pseudomonas aeruginosa ATCC#9027

[0107] Burkholderia cepacia (ATCC#25416)

[0108] Candida albicans (C. albicans) ATCC#10231

[0109] Aspergillus brasiliensis ATCC#16404

[0110] For each inoculum, add approximately 20 g of composition to a separate, sterile, capped bacterial container. Vortex the inoculum tube for approximately 15 seconds. Using a micropipette with a sterile tip, transfer approximately 0.2 mL of inoculum to the bacteriological container. Use a sterile scraper to thoroughly mix the composition with inoculum for approximately 1 minute. Store the inoculated composition at 22.5 ± 2.5 °C. Perform microbial recovery tests and evaluations on the samples at 7, 14, and 28 days post-inoculation. Before sampling, mix the inoculated composition to ensure homogeneity. Take 1 g aliquot from each inoculated sample container and dilute it in 9 mL of neutralizing agent in a spiral-topped tube with glass beads, shaking and vortexing until homogeneous. Prepare a series of dilutions from this 1:10 dilution four times. For bacteria, plate in duplicate on 90 mm plates with trypsin-soy agar (TSA); for fungi, on 150 mm plates with Sabouraud dextrose agar (SDA); and for yeast, on 90 mm plates with Sabouraud dextrose agar (SDA). Incubate samples at 22.5 ± 2.5 °C for 3–5 days (for yeast), at 22.5 ± 2.5 °C for 3–7 days (for Aspergillus brasiliensis), and at 32.5 ± 2.5 °C for 3–5 days (for bacteria). Read the plates and count the colonies. Determine log reduction by calculating the logarithm of the density per gram of inoculum at the starting point and the logarithm of recovery at 7, 14, and 28 days.

[0111] Table 3: Results of Aspergillus brasiliensis

[0112]

[0113] All samples passed for every other microorganism; however, some samples failed for *Aspergillus brasiliensis* (also known as mold). For mold, a result was achieved by having a value greater than or equal to 0 at D14 (day 14) and a value greater than or equal to 1 at D28 (day 28). The results for *Aspergillus brasiliensis* are shown in Table 3.

[0114] We have shown that even with the use of additional preservative synergists, compositions containing 45% glycerol and less than 30% water (where isocetyl alcohol is present in the composition) failed the trace mold test. Although C9 passed, it was noted that the sample contained 35% water. Surprisingly, we found that replacing isocetyl alcohol with caprylic / capric triglyceride resulted in passing the trace mold test.

Claims

1. A skincare composition comprising: a. More than 40% by weight of one or more wetting agents based on the total weight of the composition; b. A mixture of glycerides; c. One or more emollients; d. One or more skin conditioning agents; and e. Less than 35% by weight of water based on the total weight of the composition.

2. The skincare composition according to claim 1, wherein the composition is substantially free of isocetyl alcohol.

3. The skin care composition according to claim 1 or 2, wherein the humectant comprises glycerin.

4. The skin care composition according to any one of claims 1 to 3, wherein the glycerin is present in about 41% to about 50% by weight of the total weight of the composition.

5. The skin care composition according to any one of claims 1 to 4, wherein the one or more glycerides include triglycerides.

6. The skin care composition according to any one of claims 1 to 5, wherein the one or more triglycerides comprises caprylic / capric triglycerides.

7. The skin care composition according to any one of claims 1 to 6, wherein the one or more glycerides are present in an amount of about 1% to about 12% by weight.

8. The skin care composition according to any one of claims 1 to 7, wherein the one or more emollients are present in an amount of about 1% to about 10% by weight.

9. The skin care composition according to any one of claims 1 to 8, wherein the one or more emollients are selected from the group consisting of: C12-C15 alkyl benzoates; cyclodimethylsiloxanes, polydimethylsiloxanes, and mixtures thereof.

10. The skin care composition according to any one of claims 1 to 9, wherein the one or more emollients comprise polydimethylsiloxane.

11. The skin care composition according to any one of claims 1 to 10, wherein the one or more skin conditioning agents are selected from the group consisting of: glycols, cationic surfactants, and combinations thereof.

12. The skin care composition according to any one of claims 1 to 11, wherein the one or more skin conditioning agents comprise caprylyl glycol.

13. The skin care composition according to any one of claims 1 to 12, wherein the water is present in an amount of less than about 33% by weight based on the total weight of the composition.

14. A skincare composition comprising: a. Glycerin, about 42% to about 50% by weight of the total weight of the composition; b. Caprylic / capric triglycerides, about 1% to about 10% by weight of the total weight of the composition; c. Based on the total weight of the composition, about 1% to about 10% by weight of polydimethylsiloxane; d. Octyl glycol, about 0.01% to about 3% by weight of the total weight of the composition; e. From about 0.01% to about 3% by weight of the processed oat components, based on the total weight of the composition; and f. Approximately 25% by weight to approximately 32% by weight of water.

15. A method of moisturizing skin, the method comprising applying to the skin a skin care composition according to any one of claims 1 to 14.

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