A medicament for preventing and treating cassava whitefly

Abstract

The present application belongs to the technical field of pesticides, and particularly relates to a medicine for preventing and treating cassava whitefly. An insecticidal active ingredient is prepared by compounding oxadiazon with spirodien and guanidino, or by compounding oxadiazon with thiofipronil. The present application determines the toxicity of oxadiazon to cassava whitefly when compounded with spirodien or thiofipronil by adopting a leaf immersion method, and evaluates the joint action type of the compounded combination by adopting a Sun Yunpei method. It is found that the compounded combination with different mass ratios shows a synergistic effect on cassava whitefly. Compared with single components, the compounded combination is helpful to improve the prevention and treatment effect on cassava whitefly, can reduce the pesticide application dose and frequency, reduce pesticide residues and relieve environmental pressure, and thus is helpful to the green, healthy and sustainable development of the cassava industry.

Description

Technical Field

[0001] This invention belongs to the field of pesticide technology, specifically to a pesticide for controlling cassava whiteflies. Background Technology

[0002] Cassava is a typical tropical crop and a staple food for over one billion people worldwide. It is also an important specialty food and cash crop in my country. (Whitefly...) Bemisia tabaci The piercing-sucking insect is a globally harmful pest that seriously damages cassava. It can not only directly pierce and suck the plant, but also spread viral diseases, causing serious damage and losses.

[0003] Whiteflies reproduce rapidly, and chemical control remains the primary method of control. While chemical agents have proven highly effective against whitefly infestations, variations in dosage, application frequency, and long-term use of the same product have led to varying degrees of resistance in whiteflies to many existing agents, resulting in less than ideal control outcomes. Therefore, it is essential to research and develop novel compound pesticides for controlling cassava whiteflies.

[0004] Oxazosulfyl (CAS: 1616678-32-0) is a broad-spectrum benzoxazole insecticide containing an ethanesulfonylpyridine structural fragment. It exhibits good control efficacy against a variety of pests, including hemiptera, lepidopterans, coleopterans, and dipterans, and also shows good control against some mites. Current technology has reported synergistic effects of oxazolidinyl with various insecticidal agents such as chlorantraniliprole, chlorantraniliprole, methoxypiperazine, trifluralin, and cyprofen.

[0005] Through indoor survival tests, the inventors discovered that oxazolidinone, when combined with pendimethalin or thiocyanate in different mass ratios, exhibits a synergistic effect against cassava whiteflies. No related reports have been found to date. Summary of the Invention

[0006] The purpose of this invention is to provide a pesticide for controlling cassava whiteflies, so as to solve the problems existing in the prior art.

[0007] To achieve the above objectives, the present invention provides the following technical solution: An insecticidal active ingredient, wherein the insecticidal active ingredient is a compound of oxazolidinyl sulfadiazine and pendimethalin, or a compound of oxazolidinyl sulfadiazine and thiotetramine.

[0008] Furthermore, the mass ratio of the compound oxazolidinium to pendimethalin is 1-9:15-1.

[0009] Furthermore, the mass ratio of the compound oxazolidin to thiofenoxam is 1-20:10-1.

[0010] The present invention also provides an insecticidal active agent, wherein the insecticidal active agent comprises the insecticidal active ingredient.

[0011] Furthermore, the insecticidal active ingredient accounts for 0.1-70% of the total mass of the insecticidal active agent, with the remainder being auxiliary ingredients permitted for addition in pesticide science.

[0012] Furthermore, the insecticidal active ingredient accounts for 0.5-55% of the total mass of the insecticidal active agent.

[0013] The present invention also provides the application of the insecticidal active ingredient or the insecticidal active agent in the prevention and control of crop diseases and pests.

[0014] Furthermore, the crop diseases and pests include cassava whiteflies and viral diseases caused by cassava whiteflies.

[0015] Compared with the prior art, the present invention has the following beneficial effects: (1) This invention uses the leaf immersion method to determine the toxicity of oxazolidinium combined with pendimethalin or thiocyanate against cassava whiteflies, and uses the Sun Yunpei method to evaluate the synergistic effects of the combined combinations. It was found that the combined combinations with different mass ratios exhibited a synergistic effect against cassava whiteflies. Compared with single components, this helps to improve the control effect against cassava whiteflies, reduce the dosage and frequency of pesticide application, reduce pesticide residues and alleviate environmental pressure, and thus contribute to the green, healthy and sustainable development of the cassava industry.

[0016] (2) The insecticidal active ingredients of this invention are compounded with two insecticidal active ingredients. Compared with single ingredients, it helps to delay the emergence and development of drug resistance in the target pest, cassava whitefly, and can provide support for the integrated management of resistance in cassava whitefly. Detailed Implementation

[0017] The technical solution of this invention patent will be clearly and completely described below. Obviously, the described embodiments are some embodiments of this invention, but not all embodiments.

[0018] Example: Indoor bioactivity test 1. Test subjects Whiteflies were collected from cassava plants and tested for multiple generations in the laboratory using fresh, clean cassava leaves that had not been exposed to pesticides. Healthy adult whiteflies of uniform size were selected as the test subjects.

[0019] 2. Test reagents 98% oxazolidinyl sulfadiazine technical grade, 98% pendimethalin technical grade, 95% thiofenazate technical grade The test drug was dissolved in dimethyl sulfoxide and then diluted with 0.1% Triton X-100 to prepare a high-concentration single-agent stock solution. Based on the results of the preliminary test, multiple formulations were set up. Each single-agent stock solution and each formulation mixture were then diluted with 0.1% Triton X-100 to prepare 5 mass concentration gradients, with 50 mL of drug solution for each mass concentration, for later use.

[0020] 3. Test Methods The leaf immersion method was used. Fresh, clean cassava leaves that had not been exposed to pesticides were used to create leaf discs using a 22mm punch. The leaf discs were immersed in the pesticide solution for 10 seconds, then removed and air-dried. They were then placed in a glass bottle with moisturizing agar at the bottom, and the leaf discs were gently pressed to ensure close contact between the leaves and the agar. 10-15 adult whiteflies were introduced into the glass bottle, and the bottle opening was then sealed with a breathable cotton plug to allow for ventilation and prevent adult escape. The bottles were then placed in a light incubator for observation. Each treatment was replicated in triplicate, with leaf discs treated with 0.1% Triton X-100 serving as a blank control. After 36 hours, the insects were observed; those that did not move when touched with a pen tip were considered dead. The corrected mortality rate for each treatment was calculated.

[0021]

[0022] In the above formula: P -- Mortality rate, in percentages. K --The number of dead insects; N --Total number of insects treated.

[0023]

[0024] In the above formula: P 1 -- Corrected mortality rate, in % P t --Case-level mortality rate, in % P 0 -- Mortality rate in the blank control group, in percent.

[0025] 4. Data Analysis Regression analysis was performed on the logarithmic values ​​of the drug concentrations for each treatment and the corresponding corrected mortality probability values ​​to calculate the LC-1 of each treatment. 50 The co-toxicity coefficient (CTC) of the mixture was calculated using the Sun Yunpei method, and the synergistic effect of the agent was evaluated based on the calculated CTC. The results are shown in Table 1-2.

[0026] Table 1. Toxicity test results of the combination of oxazolidinone and pendimethalin against cassava whiteflies.

[0027] As shown in Table 1, within the range of 1-9:15-1, the different mass ratios of oxazolidinium and pendimethalin of the present invention exhibit a synergistic effect on cassava whiteflies, which can improve the control effect on cassava whiteflies.

[0028] Table 2. Toxicity test results of the combination of oxazolidinone and thiocyanate on cassava whiteflies.

[0029] As shown in Table 2, within the range of 1-20:10-1, the different mass ratios of oxazolidinone and thiophanate-methyl of the present invention exhibit a synergistic effect on cassava whiteflies, which can improve the control effect on cassava whiteflies.

[0030] In summary, this invention used the leaf immersion method to determine the toxicity of oxazolidinone combined with pendimethalin or thiocyanate against cassava whiteflies, and employed the Sun Yunpei method to evaluate the synergistic effects of the combined formulations. The results showed that different mass ratios of the combined formulations exhibited a synergistic effect against cassava whiteflies. Compared to single-component formulations, this approach helps improve the control efficacy against cassava whiteflies, reduces pesticide application dosage and frequency, lowers pesticide residues, and alleviates environmental pressure, thereby contributing to the green, healthy, and sustainable development of the cassava industry.

Claims

1. An insecticidal active ingredient, characterized in that, The insecticidal active ingredient is a compound of oxazolidin and pendimethalin, or a compound of oxazolidin and thiotetramine.

2. The insecticidal active ingredient according to claim 1, characterized in that, The mass ratio of the compound oxazolidinium to pendimethalin is 1-9:15-1.

3. The insecticidal active ingredient according to claim 1, characterized in that, The mass ratio of oxazolidin to thiocyanate is 1-20:10-1.

4. An insecticidal active agent, characterized in that, The insecticidal active agent includes the insecticidal active ingredient as described in claim 1.

5. The insecticidal active agent according to claim 4, characterized in that, The insecticidal active ingredient accounts for 0.1-70% of the total mass of the insecticidal active agent, with the remainder being auxiliary ingredients permitted to be added in pesticide science.

6. The insecticidal active agent according to claim 5, characterized in that, The insecticidal active ingredient accounts for 0.5-55% of the total mass of the insecticidal active agent.

7. The use of the insecticidal active ingredient according to any one of claims 1-3 or the insecticidal active agent according to any one of claims 4-6 in the prevention and control of crop diseases and pests.

8. The application according to claim 7, characterized in that, The crop diseases and pests mentioned include cassava whiteflies and viral diseases caused by cassava whiteflies.

Images