A kind of backup sow feed for promoting vitamin D absorption and utilization and preparation method

CN122804907APending Publication Date: 2026-09-25BEIJING SANYUAN BREEDING TECH CO LTD FEED BRANCH
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Patent Information

Application Number
CN202611170016.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-08-04
Publication Date
2026-09-25

AI Technical Summary

Technical Problem

[0004]现有的在一些饲料中添加了蜜炙黄芪,但是蜜炙黄芪只是起到常规作用,其进一步的作用没有被发现

Benefits of technology

[0019]本发明制备的后备母猪饲料在对母猪进行喂养后25(OH)D3体内含量得到了明显提升,腿部疾病发病率得到了降低、发情率和受胎率得到明显提升。

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Abstract

The application discloses a kind of backup sow feed for promoting vitamin D absorption and utilization, belong to pig feed preparation field, comprising: corn, honeyed astragalus membranaceus, oligo-chitosan, stone powder, soybean meal, compound premix, wheat bran, fish meal, calcium hydrogen phosphate;The preparation method of honeyed astragalus membranaceus is as follows: after micro-pulverization to astragalus membranaceus, honey is heated to boiling, and the pulverized astragalus membranaceus is added, and is uniformly fried;The compound premix includes according to weight part: bacillus subtilis, vitamin premix feed SV04, trace element premix SM02.This application can improve the absorption of sow to 25-hydroxyvitamin D3 (25 (OH) D3), improve estrus, and the like.
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Description

Technical Field

[0001] This invention relates to the field of sow feed preparation. Background Technology

[0002] Vitamin D3 deficiency leads to impaired reproductive capacity in animals, and the metabolism of vitamin D3 in the animal body may be involved in regulating the initiation of estrus. Osteocalcin, a protein secreted by the skeleton, can regulate energy metabolism in animals, and also affects male reproduction and may participate in the regulation of estrus initiation in females.

[0003] Honey-processed Astragalus is a commonly used processed form of the Chinese herb Astragalus. It is made by mixing high-quality Astragalus slices (usually oblique or round slices) with refined honey (honey that has been heated and boiled), and then processing it through steps such as soaking and stir-frying.

[0004] Some existing feeds contain honey-processed astragalus, but this only plays a routine role, and its further effects have not been discovered. For example, patent application number 201910258001.9 discloses a highly efficient, green, lactation-promoting feed for lactating sows that improves the bitterness of traditional Chinese medicine. The feed includes a compound traditional Chinese medicine formula, which includes honey-processed astragalus, etc. The honey-processed astragalus is used in combination with codonopsis, etc., mainly for replenishing qi.

[0005] Oligochitosan is a functional high-molecular-weight polysaccharide obtained by esterification modification of natural glucomannan. Its basic structure consists of glucose and mannose linked by β-1,4 glycosidic bonds, and its physical and chemical properties are significantly optimized by introducing ester groups such as acetyl groups.

[0006] Vitamin D is the collective term for vitamin D2 or D3 ingested from food and vitamin D3 produced in the skin. Vitamin D is first converted to 25-hydroxyvitamin D (25-(OH)D) in the liver by 25-hydroxylase. 25-(OH)D is then converted to 1,25-(OH)2D in the kidneys by 25-(OH)D-1α-hydroxylase. Vitamin D is a fat-soluble vitamin, and its absorption mainly depends on the formation of microparticles from bile salts in the intestines, through passive diffusion. 25-(OH)D3 (clinically often combined with D2 and reported as total 25-(OH)D) has the highest concentration in the blood, a long half-life, and is not subject to drastic short-term hormonal regulation. It accurately reflects the body's total reserves from all sources, much like a "stock balance," and is therefore recognized as the gold standard for evaluating vitamin D nutritional status.

[0007] 25-Hydroxyvitamin D3 (25(OH)D3) (a type of 25-hydroxyvitamin D) plays a crucial role in the physiological functions of gilts. It has a significant impact on skeletal development and maintenance, calcium and phosphorus metabolism balance, and reproductive performance. Regarding skeletal development, gilts are in a growth stage and require a good skeletal structure to support their reproductive activities in adulthood. 25(OH)D3 promotes the absorption of calcium and phosphorus in the intestines, leading to greater calcium and phosphorus deposition in the bones, which contributes to bone mineralization and increased strength. Appropriate 25(OH)D3 levels ensure normal skeletal development in gilts, reduce the incidence of limb and hoof diseases, and prevent skeletal problems from affecting their reproductive lifespan. From the perspective of calcium and phosphorus metabolism balance, 25(OH)D3 regulates the secretion and action of related hormones such as parathyroid hormone, thereby maintaining stable levels of blood calcium and phosphorus. When the body's 25(OH)D3 content is insufficient, it will interfere with calcium and phosphorus metabolism, which may lead to decreased blood calcium and thus cause reproductive disorders in sows, such as abnormal estrus and reduced conception rate. Summary of the Invention

[0008] The purpose of this invention is to address the problems existing in the prior art by disclosing a feed for gilts that promotes vitamin D absorption and utilization, comprising, by weight: 1247 portions of corn; Honey-processed Astragalus membranaceus 1.5 parts; 1.5 parts of oligochitosan; 24 parts stone powder; 440 portions of soybean meal; 40 parts of compound premix; 200 portions of wheat bran; 30 servings of red fish powder; 16 portions of dicalcium phosphate.

[0009] The corn mentioned is common corn, which is the main component of the feed. The honey-processed astragalus is prepared according to the method of this invention, and the honey-processed astragalus can be 0.5-2 parts, preferably 1.5 parts. The oligochitosan can be purchased directly from the market. The limestone powder is common and its main function is to supplement calcium. The soybean meal is used to provide protein. The compound premix is ​​prepared using the formula of this invention.

[0010] In the preferred embodiment, the preparation method of honey-processed astragalus is as follows: after micronizing the astragalus, heat the honey to boiling, add the micronized astragalus, stir-fry evenly, wherein the weight ratio of honey to astragalus is (1-2):4.

[0011] In a preferred embodiment, the compound premix comprises, by weight, Bacillus subtilis, vitamin premixed feed SV04, animal blood extract, amino acid iron complex, flavoring agent, phytase, yeast selenium, and trace element premix SM02.

[0012] In a preferred embodiment, the trace element premix SM02 comprises: ferrous sulfate, zinc sulfate, manganese sulfate, iron complex of amino acids, zeolite powder, copper sulfate, sodium selenite, cobalt chloride, and chromium methionine.

[0013] In a preferred embodiment, the vitamin premixed feed SV04 comprises, by weight: nicotinamide, vitamin K3, vitamin E, vitamin B2, vitamin D3, folic acid, vitamin B6, vitamin B12, vitamin A, calcium pantothenate, etc.

[0014] A method for preparing feed for gilts, comprising the following steps: S1: Preparation of honey-processed Astragalus membranaceus; S2: Preparation of composite premix; S3: Mix and stir the honey-processed astragalus, compound premix, and other materials.

[0015] In the preferred embodiment, the method for preparing honey-processed astragalus is as follows: after micronizing the astragalus, heat the honey to boiling, add the micronized astragalus, and stir-fry evenly.

[0016] In the preferred embodiment, the step of preparing the compound premix includes preparing vitamin premixed feed SV04 and preparing trace element premixed feed SM02.

[0017] In the preferred embodiment, the steps for preparing vitamin premixed feed SV04 include: mixing and stirring nicotinamide, vitamin K3, vitamin E, 80% vitamin B2, vitamin D3, 99% folic acid, vitamin B6, 1% vitamin B12, vitamin A, 99% calcium pantothenate, 2% biotin, ethoxyquinoline, 98% vitamin B1, and rice husk powder.

[0018] In the preferred embodiment, the step of preparing the trace element premix SM02 includes: mixing and stirring ferrous sulfate, zinc sulfate, manganese sulfate, amino acid iron complex, zeolite powder, copper sulfate, sodium selenite, cobalt chloride, chromium methionine, calcium iodate, etc.

[0019] The feed for gilts prepared in this invention significantly increased the content of 25(OH)D3 in the bodies of gilts after feeding them, reduced the incidence of leg diseases, and significantly improved the estrus rate and conception rate. Detailed Implementation

[0020] The present invention will now be described in detail.

[0021] I. Preparation of Vitamin Premix SV04

[0022] The raw materials were mixed according to the proportions in Table 1 to prepare vitamin premix SV04.

[0023] Table 1 II. Preparation of Trace Element Premix SM02 The raw materials were mixed according to the proportions in Table 2 to prepare the trace element premix SM02.

[0024] Table 2 III. Preparation of Compound Premix for Gilts Prepare a 2% compound premix for gilts using the raw materials listed in Table 3.

[0025] Table 3 IV. Preparation of feed for gilts The following formula ratio was used to prepare feed for gilts (with a weight of kg). A control group and an experimental group were prepared separately. The method for preparing honey-processed astragalus was to pulverize the astragalus, heat the honey to boiling, add the pulverized astragalus, and stir-fry evenly. The weight ratio of honey to astragalus was 1:4.

[0026] Table 4 V. Experimental Design The experiment selected 800 Large White sows around 150 days old and randomly divided them into a control group and an experimental group (Examples 1-3). Each group had 8 replicates, with 25 sows in each replicate. During pregnancy, the control group was fed a basal diet, while the experimental group was fed an experimental diet. After farrowing, they were fed the same lactating sow feed. The experiment lasted until weaning and estrus.

[0027] After 10% of the pigs were in estrus at around 180 days of age, estrus synchronization was performed. The pigs were not bred during the first estrus and were bred during the second estrus. Blood was collected from the anterior vena cava before brooding, and the serum was centrifuged at 4000 r / min for 5 minutes to detect the 25(OH)D3 content and perform other statistical analysis. The average value of 25 pigs in each replicate was taken for statistical analysis.

[0028] VI. Results The content of 25(OH)D3 was determined, the data were recorded, and the data were analyzed using analytical software. The results are shown in Table 5-1: Table 5-1 The results showed that experimental group 1 had a significant effect compared to the control group, indicating that the addition of honey-processed astragalus affected the 25(OH)D3 content and had a promoting effect. Experimental group 2 did not have a significant effect compared to the control group, indicating that the addition of oligochitosan alone did not affect the 25(OH)D3 content. The effect of experimental group 3 was significantly stronger than that of experimental group 1, with a strong statistical difference between the two, proving that honey-processed astragalus and oligochitosan have a certain synergistic effect. Adding oligochitosan to honey-processed astragalus can increase the 25(OH)D3 content, and experimental group 3 showed a strong statistical difference compared to the control group. Data analysis using analysis software yielded the results shown in Table 5-2, indicating that honey-processed astragalus and oligochitosan have a significant synergistic effect. The reason for this is that honey-processed astragalus itself enhances the body's basal metabolism and absorption capacity through its active ingredients (such as astragalus polysaccharides and astragaloside A); while oligochitosan creates favorable conditions by improving the microecology and physical environment.

[0029] Table 5-2 2. Leg disease detection results are shown in Table 6.

[0030] Table 6 3. Estrus rate Estrus rate test as follows Table 7 4. Piglet growth performance Table 8 Growth Performance of Piglets As can be seen from Table 6, the incidence of leg diseases in Examples 1 and 3 was reduced, while the estrus rate and conception rate were increased, which was attributed to the increase in 25(OH)D3 content.

[0031] As can be seen from Table 7, the estrus rate of Examples 1 and 3 was improved compared with the control group.

[0032] As can be seen from Table 8, the growth performance of piglets was significantly improved after sows were fed the experimental group feed.

[0033] In summary, the feed of the present invention can significantly increase 25(OH)D3 in the serum of sows, which is beneficial to the reproduction of sows and the growth of piglets.

Claims

1. A feed for gilts that promotes vitamin D absorption and utilization, characterized in that, include: Corn, honey-processed astragalus, oligochitosan, limestone powder, soybean meal, compound premix, wheat bran, red fish meal, Calcium hydrogen phosphate.

2. The feed for gilts that promotes vitamin D absorption and utilization according to claim 1, characterized in that, In parts by weight: 1247 portions of corn; Honey-processed Astragalus membranaceus 1.5 parts; 1.5 parts of oligochitosan; 24 parts stone powder; 440 portions of soybean meal; 40 parts of compound premix; 200 portions of wheat bran; 30 servings of red fish powder; 16 portions of dicalcium phosphate.

3. The feed for gilts that promotes vitamin D absorption and utilization according to claim 2, characterized in that, The compound premix includes: Bacillus subtilis, vitamin premixed feed SV04, and trace element premixed feed SM02.

4. The gilt feed for promoting vitamin D absorption and utilization according to claim 3, characterized in that, The trace element premix SM02 includes: ferrous sulfate, zinc sulfate, manganese sulfate, iron complex of amino acids, copper sulfate, sodium selenite, cobalt chloride, and chromium methionine.

5. The gilt feed for promoting vitamin D absorption and utilization according to claim 3, characterized in that, The vitamin premixed feed SV04 includes: nicotinamide, vitamin K3, vitamin E, vitamin B2, vitamin D3, folic acid, calcium pantothenate, and biotin.

6. A method for preparing gilt feed according to any one of claims 1-5, characterized in that, The steps are as follows: S1: Preparation of honey-processed Astragalus membranaceus; S2: Preparation of composite premix; S3: Mix and stir the honey-processed astragalus, compound premix, and other materials.

7. The method for preparing gilt feed according to claim 6, characterized in that, The method for preparing honey-processed astragalus is as follows: After micro-grinding the astragalus, heat the honey to boiling, add the grinding astragalus, and stir-fry evenly.

8. The method for preparing gilt feed according to claim 7, characterized in that, The steps for preparing the compound premix include preparing vitamin premixed feed SV04 and micronutrient premixed feed SM02.

9. The method for preparing gilt feed according to claim 8, characterized in that, The steps for preparing vitamin premixed feed SV04 include: mixing and stirring nicotinamide, vitamin K3, vitamin E, 80% vitamin B2, vitamin D3, 99% folic acid, vitamin B6, 1% vitamin B12, vitamin A, 99% calcium pantothenate, 2% biotin, ethoxyquinoline, 98% vitamin B1, and rice husk powder.

10. The method for preparing gilt feed according to claim 8, characterized in that, The steps for preparing the trace element premix SM02 include: mixing and stirring ferrous sulfate, zinc sulfate, manganese sulfate, amino acid iron complex, zeolite powder, copper sulfate, sodium selenite, cobalt chloride, chromium methionine, and calcium iodate.

Citation Information

Patent Citations

  • Efficient and green feed for promoting lactation of lactating sows and with bitterness of Chinese herbal medicine improved and preparation method thereof

    CN109793102A