A tumor sampling device with drainage function

Abstract

The application relates to the technical field of medical devices, in particular to a tumor sampling device with a drainage function. A needle core and a trocar are inserted into a lesion position, and a negative pressure system is controlled to work during the insertion process. A small amount of exudate generated by puncture damage contains exudate generated by puncture damage. Blood and tissues around the lesion are sucked through a drainage port and a connecting hole. When the body fluid enters the inside of the cavity structure, the body fluid contacts a plurality of spiral ribs. The spiral ribs have a cutting, crushing and conveying effect on the tissue debris in the body fluid. Meanwhile, the contact area of the tissue in the body fluid and the cavity structure is reduced, and the acceleration through the cross-section change section can effectively prevent the tissue from adhering, accumulating and blocking the cavity structure, further reduces the blocking risk, forms a negative pressure environment around the needle core, avoids the accumulation of the lesion around the needle core and stimulates the nerves, and thus the pain of the patient is reduced.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a tumor sampling device with drainage function. Background Technology

[0002] Cancer genes: Human cells contain proto-oncogenes and tumor suppressor genes. When these two types of genes mutate under certain conditions, cancer can result. Tumors are one manifestation of cancer. Gene therapy targets and eliminates cancer cells. Essentially, cancer is a genetic disease; its occurrence, development, and recurrence are all related to gene mutations, deletions, and malformations.

[0003] For example, a tumor puncture sampling device with authorization announcement number CN120899305B changes the shape of the needle core tip so that the end face of the sampling groove tip is flush with the end face of the needle core tip. This allows the tumor tissue to be directly cut during the needle core insertion process, eliminating the problem of the solid cylindrical puncture needle pushing the tumor tissue away, as is present in the prior art. During cannula insertion, the tissue sample is cut off from the surrounding tumor tissue. When the cannula moves a preset distance, the sealing mechanism cuts off the tip of the tissue in the sampling groove, completely separating the sample from the tumor tissue. The sealing component seals the gap between the needle core and the cannula, preventing the tissue sample from detaching from the sampling groove. This invention solves the problem of insufficient tissue sampling caused by the needle core pushing away tumor tissue during puncture sampling in the prior art. However, in the sampling device described above, the tip of the puncture needle will damage the tumor tissue structure after puncturing the lesion and sampling, resulting in a large amount of blood and other body fluids around the needle tip. The above-mentioned device cannot absorb the body fluids that appear during puncture, which can easily accumulate and irritate nerves, increasing the patient's pain. Meanwhile, the aforementioned documents show that the samples themselves may have some body fluid attached during sampling, which can cause the samples to easily stick to the inside of the sampling tank, making it difficult to sample. Summary of the Invention

[0004] The purpose of this invention is to solve the problems mentioned in the background art and to provide a tumor sampling device with drainage function.

[0005] To achieve the above objectives, the present invention provides the following technical solution: Design a tumor sampling device with drainage function, including The needle core is a cylindrical body with a pointed structure on one side, a sampling groove near the pointed position, and a hollow internal structure. The flow guiding structure is a linearly extending protruding structure distributed inside the cavity structure; The drainage port is an open structure with a hollow cavity structure and smooth end faces, located on the side of the needle core adjacent to the sampling groove.

[0006] Preferably, the flow guiding structure consists of at least one rib, and the height of the rib is 1 / 5 to 1 / 4 of the inner diameter of the cavity structure.

[0007] Preferably, multiple guide blocks are provided at both ends of the rib, and the multiple guide blocks are distributed at intervals along the extension direction of the rib, and the inclination angle of the multiple guide blocks is the same as the liquid flow direction inside the cavity structure.

[0008] Preferably, the middle section of the cavity structure is provided with a cross-sectional change section, and its flow guiding structure can extend to the cross-sectional change section.

[0009] Preferably, the end of the needle core away from the tip structure extends to the connecting cylinder, and the end of the connecting cylinder away from the needle core is movably connected to a connecting cap. The end of the connecting cap is provided with a connector, and the interior of the connecting cylinder is provided with a collecting structure.

[0010] Preferably, the collecting structure is a cylindrical structure with a sealed side and a flow gap, and a connecting frame is provided on the side of the collecting structure adjacent to the needle core, and the connecting frame is detachably connected to the needle core; The collecting structure has a bent section at the end away from the connecting frame, and the maximum outer diameter end of the bent section is in contact with the inner wall of the connecting cylinder.

[0011] Preferably, a support structure is provided at the middle section of the end of the sampling groove. The support structure is composed of several support structure units, and the inclination angle of the several support structure units is all directed towards the tip structure of the needle core. The support structure is provided with connecting holes on both sides, the connecting holes are connected to the cavity, and a protrusion is provided above the connecting hole, with a flow space provided between the protrusion and the connecting hole.

[0012] Preferably, a connecting seat is provided on one side of the needle core adjacent to the connecting cylinder, a firing structure is provided inside the connecting seat, a sleeve needle is provided on the outer wall of the needle core, and one side of the sleeve needle is located inside the connecting seat so as to cooperate with the firing structure.

[0013] Preferably, the needle has a notch on the side adjacent to the drainage port, the notch corresponding to the drainage port, so that the needle does not cover the drainage port.

[0014] The tumor sampling device with drainage function proposed in this invention has the following advantages: the needle core and sheath are inserted into the lesion site, and the negative pressure system is controlled during the insertion process. Since the small amount of exudate generated by the puncture injury will contain the exudate generated by the puncture injury, the blood and tissue around the lesion are absorbed through the drainage port and connecting hole. When the body fluid enters the cavity structure, it comes into contact with multiple spiral ribs. The spiral ribs have the function of cutting, breaking and transporting tissue debris in the body fluid, while reducing the contact area between the tissue in the body fluid and the cavity structure. Furthermore, the acceleration through the cross-sectional change section can effectively prevent tissue adhesion, accumulation and blockage of the cavity structure, further reducing the risk of blockage. The negative pressure environment around the needle core can avoid accumulation around the lesion and stimulation of nerves, thereby reducing the patient's pain. The ribs increase the strength of the needle core and prevent it from bending. When body fluids carry tissues to the collection structure, the tissues can be separated from the body fluids. The conical cylindrical structure increases the surface area of ​​the body fluids and the collection structure, preventing accumulation and blockage of the collection structure. At the same time, during the filtration process, the tissues flow along the end face of the collection structure, allowing some tissues to accumulate at the bend of the bend, thus achieving the collection of tissues from the body fluids. The support structure reduces the contact area between the sampling tank and the sample. The negative pressure system connects the cavity structure and the connection hole to adsorb the body fluid on the sample surface inside the sampling tank. The protrusions support the sample and the connection hole, ensuring a gap between the connection hole and the sample to facilitate the flow of body fluid. This makes the sample surface drier, reduces the adhesion between the sample and the sampling tank, and facilitates sampling and biopsy. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of the present invention; Figure 2 This is a structural exploded view of the present invention; Figure 3 This is a schematic diagram of the needle core, ribs, and support structure in this invention; Figure 4 This is a partial cross-sectional view of the cavity structure of the needle core in this invention; Figure 5 This is a partial structural diagram of the ribs and guide blocks in this invention. Figure 6 This is a schematic diagram of the needle core, protrusion, and support structure in this invention; Figure 7 This is a cross-sectional view of the collecting structure, connecting cylinder, and connecting cover in this invention.

[0016] In the diagram: 1. Needle core; 101. Sampling groove; 102. Connecting hole; 103. Protrusion; 104. Support structure; 105. Cavity structure; 1051. Cross-sectional change section; 106. Drainage port; 2. Sleeve needle; 201. Notch; 3. Rib; 301. Guide block; 4. Connecting cylinder; 5. Connecting cover; 6. Connecting head; 7. Collection structure; 701. Connecting frame; 702. Bending part; 8. Connecting seat; 9. Firing structure. Detailed Implementation

[0017] The present invention will be further described below with reference to the accompanying drawings: like Figure 1 , Figure 2 , Figure 3 and Figure 4 As shown, a tumor sampling device with drainage function includes a needle core 1, one side of which has a pointed structure. Near the pointed end is a sampling groove 101 and a cylindrical body with an internal cavity structure 105. The minimum space of the cavity structure 105 is located below the sampling groove 101. The pointed structure of the needle core 1 is used to puncture the lesion. The sampling groove 101, in cooperation with the needle 2, obtains tumor tissue and stores it inside the sampling groove 101. The cavity structure 105 is connected to an external negative pressure system to absorb blood and tissue around the lesion during the sampling process. Since the small amount of exudate generated by the puncture injury contains pain-inducing substances such as prostaglandins and histamine, its accumulation will aggravate pain and edema. The negative pressure environment formed around the needle core can prevent accumulation around the lesion and nerve stimulation, thereby reducing patient suffering. The drainage structure is distributed within the cavity structure 105. The internal linear protrusion structure enhances the needle core's resistance to bending, thereby improving its strength and preventing deformation during insertion into the lesion. Furthermore, when body fluid flows within the cavity structure, the contact with the drainage structure reduces direct contact between tissues and the inner wall of the cavity structure 105, preventing blockage. The drainage port 106 is an open structure connected to the cavity structure 105 with smooth, rounded edges. In this embodiment, the drainage port 106 can be rectangular. The smooth edges prevent traction on the lesion and pain during needle insertion. The number of drainage ports can be 2-6, preferably 4. Multiple drainage ports 106 are provided to prevent blockage when a single port 106 is blocked. The port 106 is located on the side of the needle core adjacent to the sampling groove 101.

[0018] The drainage structure consists of at least one rib 3, and the height of the rib 3 is 1 / 5 to 1 / 4 of the inner diameter of the cavity structure 105. In this embodiment, the rib 3 is spiral in shape. The spiral rib 3 forms a continuous spiral drainage channel inside the cavity, allowing the accumulated fluid, blood, and tissue exudate to flow smoothly along the spiral path, ensuring the stable formation of negative pressure in the lesion area. At the same time, the spiral rib 3 can support and suspend the sampling tissue strip, preventing it from sticking tightly to the inner wall of the cavity structure 105 and avoiding the tissue from blocking the drainage channel due to negative pressure adsorption. In addition, the spiral structure has the function of cutting, breaking, and transporting tissue debris, further reducing the risk of blockage and ensuring continuous and unobstructed sampling and drainage.

[0019] When the height of rib 3 is greater than 1 / 4 of the inner diameter of the cavity structure 105, the area for fluid flow inside the cavity structure 105 of the needle core 1 will be reduced, resulting in increased drainage resistance and increased tissue traction, thus increasing patient pain. When the height of rib 3 is less than 1 / 5 of the inner diameter of the cavity structure 105, the height of rib 3 is insufficient and cannot effectively suspend the tissue sample. The tissue will still adhere tightly to the inner wall of the cavity structure 105 and be adsorbed and blocked under negative pressure, thus losing its anti-blocking function. Furthermore, if rib 3 is too low, it cannot form a stable spiral flow channel, significantly reducing the drainage effect and failing to guarantee stable negative pressure. If rib 3 is too low, it cannot effectively strengthen the needle core 1, resulting in insufficient rigidity and easy bending and deformation during puncture, affecting puncture accuracy. The optimal height of rib 3 is 1 / 4 of the inner diameter of the cavity structure 105, ensuring the strength of the needle core 1 while providing sufficient space in the cavity structure 105 to effectively support the tissue and prevent blockage.

[0020] In other embodiments, the rib 3 can be wavy, which can disturb the tissue during the flow of body fluid, thus preventing the cavity structure 105 from becoming blocked, while also enhancing the strength of the needle core.

[0021] The number of ribs 3 can be 1, 2, 3, 4, or 5, preferably 4, to reduce the contact area between the tissue in the body fluid and the cavity structure 105 and improve the anti-clogging properties of the cavity structure 105.

[0022] like Figure 5 As shown, multiple guide blocks 301 are respectively provided at both ends of the rib 3, and the multiple guide blocks 301 are spaced apart along the extension direction of the rib 3. The inclination angle of the multiple guide blocks 301 is the same as the liquid flow direction inside the cavity structure 105. Figure 5 The direction of liquid flow is from left to right. The inclination angle between the guide block 301 and the rib 3 is 30° to 45°, preferably 35°. When the tissue in the body fluid flows along the rib 3 and comes into contact with the guide block 301, the tissue in the body fluid gains acceleration, which effectively prevents the body fluid tissue from being stuck inside the cavity structure 105, and can also break down larger debris.

[0023] like Figure 4 As shown, the middle section of the cavity structure 105 is provided with a cross-sectional change section 1051, and its flow guiding structure can extend to the cross-sectional change section 1051. The inner diameter of the cross-sectional change section 1051 is smaller than the inner diameter of the cavity structure 105, and the inner diameter is 3 / 2 of the inner diameter of the cavity structure 105. The acceleration of the flow of body fluid carrying tissue through the cross-sectional change section 1051 can effectively prevent tissue adhesion, accumulation, and blockage of the needle channel.

[0024] like Figure 2 and Figure 6 As shown, the end of the needle core 1 away from the tip structure extends to the connecting tube 4. The end of the connecting tube 4 away from the needle core 1 is movably connected to the connecting cover 5. The connecting cover 5 and the connecting tube 4 can be connected by threads or snap-fit, which can realize the disassembly and separation between the connecting cover 5 and the connecting head 4. The connecting head 6 is used to connect to an external negative pressure system to realize the drainage of body fluid. The end of the connecting cover 5 is provided with the connecting head 6, and the inside of the connecting tube 4 is provided with a collection structure 7. The collecting structure 7 is a cylindrical structure with a sealed end and a flow gap. In this embodiment, the collecting structure 7 is a conical cylindrical structure with its sealed end facing the needle core 1. The minimum cross-sectional dimension of the collecting structure 7 is 4 / 5 of the maximum inner diameter of the cavity structure 105. When body fluid carrying tissue flows into the collecting structure 7, it can separate the tissue from the body fluid. The conical cylindrical structure increases the area between the body fluid and the collecting structure 7, avoiding accumulation and blockage. In other embodiments, the opening end of the collecting structure 7 is an arc surface. A connecting frame 701 is provided on the side of the collecting structure 7 adjacent to the needle core 1. The connecting frame 701 is detachably connected to the needle core 1. The end of the collecting structure 7 away from the connecting frame 701 is provided with... The device includes a bending section 702, with an angle of 70° to 90°, preferably 85°, between the bending section and the collection structure 7. During filtration, the tissue flows along the end face of the collection structure 7, allowing some tissue to accumulate at the bending position of the bending section 702. This further increases the contact area between the collection structure and the body fluid. The maximum outer diameter end of the bending section 702 is in contact with the inner wall of the connecting cylinder 4. A rubber sealing structure is provided at the contact end between the bending section 702 and the connecting cylinder 4 to seal the gap between them. The connecting frame 701 and the needle core 1 can be connected by a thread or by abutment, ensuring that the collection mechanism 7 can be disassembled to allow for further sampling of the collected tissue.

[0025] like Figure 6As shown, a support structure 104 is provided at the middle section of the sampling groove 101. The support structure 104 is composed of several individual support structures 104, and the inclination angle of each individual support structure 104 is directed towards the tip of the needle core 1. Connecting holes 102 are provided on both sides of the support structure 104, and the connecting holes 102 communicate with the cavity. A protrusion 103 is provided above the connecting hole 102, and a flow space is provided between the protrusion 103 and the connecting hole 102. The number of individual support structures can be 6, 7, 8, 9, or 10, preferably 8. The included angle between the individual support structure and the sampling groove 101 is 30° to 60°, preferably 45°. The height of the individual support structure is the same as that of the sampling groove 101. The rounded corners at the end of the sampling slot 101, which is 1 / 5 of the depth, prevent scraping of the lesion and increase the patient's pain. The external negative pressure system is connected to the connecting hole 102 through the cavity structure 105, thereby absorbing the body fluid around the sampling slot 101. At the same time, after the needle 2 cuts the tumor at the lesion site, it can absorb the surface body fluid of the sample after sampling, making the sample surface relatively dry and avoiding the situation where the sample surface has too much body fluid, which would cause the sampling slot 101 to stick and make sampling inconvenient. The protrusion 103 can support the sample and the connecting hole 102, ensuring that there is a gap between the connecting hole 102 and the sample to facilitate the flow of body fluid.

[0026] like Figure 1 and Figure 2 As shown, a handle is provided on the needle 2 away from the notch 201. Moving the handle connects the needle 2 to the firing mechanism 9, simultaneously compressing the firing spring inside the firing mechanism 9. After triggering the firing button, the firing spring drives the needle 2 to fire, thus cooperating with the needle core 1 to achieve sampling. A connecting seat 8 is provided on the side of the needle core 1 adjacent to the connecting cylinder 4. The firing mechanism 9 is located inside the connecting seat 8. The needle 2 is located on the outer wall of the needle core 1, with one side of the needle 2 located inside the connecting seat 8, allowing it to cooperate with the firing mechanism 9. A notch 201 is provided on the side of the needle 2 adjacent to the drainage port 106. The notch 201 corresponds to the drainage port 106, preventing the needle from covering the drainage port 106 and avoiding the situation where the needle 2 cuts the tumor around the drainage port 106 during the cutting process, causing blockage of the drainage port.

[0027] Specifically, the connector 6 is connected to an external negative pressure system, and then the sheath 2 is connected to the firing structure 9. The needle core 1 and the sheath 2 are then inserted into the lesion. During the insertion, the negative pressure system is controlled. Since the small amount of exudate generated by the puncture injury contains the exudate generated by the puncture injury, the blood and tissue around the lesion are absorbed through the drainage port 106 and the connecting hole 102. A negative pressure environment is formed around the needle core, which can prevent the accumulation around the lesion and the stimulation of nerves, thereby reducing the patient's pain. When the body fluid enters the cavity structure 105, it comes into contact with multiple spiral ribs 3. The spiral ribs 3 have the function of cutting, breaking and transporting tissue debris in the body fluid, reducing the contact area between the tissue in the body fluid and the cavity structure 105, further reducing the risk of blockage. At the same time, the ribs 3 increase the strength of the needle core 1 and prevent the needle core 1 from bending. The acceleration of the flow of body fluid carrying tissue through the cross-sectional change section 1051 can effectively prevent tissue adhesion, accumulation and blockage of the cavity structure 105. When the body fluid carrying the tissue flows into the collection structure 7, the tissue and body fluid can be separated. The conical cylindrical structure increases the area of ​​the body fluid and the collection structure 7, avoiding accumulation and blockage of the collection structure 7. At the same time, during the filtration process, the tissue flows along the end face of the collection structure 7, allowing some tissue to accumulate at the bend of the bend 702. Then, the firing button is triggered, and the tumor is cut by the needle 2, so that the sample stays inside the sampling groove 101. The support structure 104 reduces the contact area between the sampling groove 101 and the sample. The negative pressure system is connected to the connecting hole 102 through the cavity structure 105, adsorbing the body fluid on the sample surface inside the sampling groove 101. The protrusion 103 supports the sample and the connecting hole 102, ensuring that there is a gap between the connecting hole 102 and the sample, which facilitates the flow of body fluid, makes the sample surface relatively dry, and reduces the adhesion between the sample and the sampling groove 101, thus facilitating sampling and biopsy. After the sample is removed from the sampling slot 101, the collection structure 7 is disassembled, and the tissue attached to the surface is recycled to achieve secondary sampling.

[0028] The above content is only a preferred embodiment of the present invention. For those skilled in the art, many changes can be made in the specific implementation and application scope based on the ideas of the present invention. As long as these changes do not depart from the concept of the present invention, they all fall within the protection scope of this patent.

Claims

1. A tumor sampling device with drainage function, characterized in that: include The needle core is a cylindrical body with a pointed structure on one side, a sampling groove near the pointed position, and a hollow internal structure. The flow guiding structure is a linearly extending protruding structure distributed inside the cavity structure; The drainage port is an open structure with a hollow cavity structure and smooth end faces, located on the side of the needle core adjacent to the sampling groove.

2. The tumor sampling device with drainage function according to claim 1, characterized in that: The flow guiding structure consists of at least one rib, and the height of the rib is 1 / 5 to 1 / 4 of the inner diameter of the cavity structure.

3. A tumor sampling device with drainage function according to claim 2, characterized in that: Multiple guide blocks are provided at both ends of the rib, and the multiple guide blocks are distributed at intervals along the extension direction of the rib. The inclination angle of the multiple guide blocks is the same as the liquid flow direction inside the cavity structure.

4. A tumor sampling device with drainage function according to claim 1, characterized in that: The cavity structure has a cross-sectional change section in the middle section, and its flow guiding structure can extend to the cross-sectional change section.

5. A tumor sampling device with drainage function according to claim 1, characterized in that: The end of the needle core away from the tip structure extends to the connecting tube, and the end of the connecting tube away from the needle core is movably connected to a connecting cap. The end of the connecting cap is provided with a connector, and the interior of the connecting tube is provided with a collecting structure.

6. A tumor sampling device with drainage function according to claim 5, characterized in that: The collecting structure is a cylindrical structure with a sealed side and a flow gap. A connecting frame is provided on the side of the collecting structure adjacent to the needle core. The connecting frame and the needle core are detachably connected. The collecting structure has a bent section at the end away from the connecting frame, and the maximum outer diameter end of the bent section is in contact with the inner wall of the connecting cylinder.

7. A tumor sampling device with drainage function according to claim 1, characterized in that: A support structure is provided at the middle section of the end of the sampling groove. The support structure is composed of several support structure units, and the inclination angle of the several support structure units is all facing the tip structure of the needle core. The support structure is provided with connecting holes on both sides, the connecting holes are connected to the cavity, and a protrusion is provided above the connecting hole, with a flow space provided between the protrusion and the connecting hole.

8. A tumor sampling device with drainage function according to claim 1, characterized in that: A connecting seat is provided on one side of the needle core adjacent to the connecting cylinder. A firing structure is provided inside the connecting seat. A sleeve needle is provided on the outer wall of the needle core. One side of the sleeve needle is located inside the connecting seat and can cooperate with the firing structure.

9. A tumor sampling device with drainage function according to claim 8, characterized in that: The needle has a notch on one side near the drainage port, and the notch corresponds to the drainage port so that the needle does not cover the drainage port.

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