Devices, systems, uses, scaffolds for ablation treatment of the digestive tract

Abstract

The application relates to a device for ablation treatment of human digestive tract, which comprises an expandable component, the expandable component comprises a supporting framework and a flexible electrode film, the electrode film is wound on the supporting framework, the supporting framework is connected with one component, and the inner end of the electrode film is connected with the supporting framework; the outer end of the electrode film is connected with another component; the number of turns of the electrode film is changed by relative rotation between the one component and the another component, and then the radial direction of the supporting framework is changed; the scheme of the disclosure realizes controllable operation of the expansion and contraction process of the electrode film, the supporting framework can effectively support the electrode film, the radial outward support of the electrode film in the expansion process and the expansion working state is guaranteed, and the electrode film is well matched with the inner wall of the digestive tract.

Description

[0001] This disclosure claims priority to four Chinese patent applications filed on August 26, 2025, with application number CN2025112031193; filed on September 16, 2025, with application number CN2025113237920; filed on February 11, 2026, with application number CN2026102021749; and filed on April 7, 2026, with application number CN2026104522821, the entire contents of which are incorporated herein by reference. Technical Field

[0002] This disclosure relates to a medical device, particularly a device for applying energy to the digestive tract to ablate its tissues. Background Technology

[0003] In the prior art, CN114786605A discloses a device for duodenal pulsed electric field therapy. This device adapts to the shape of the duodenal wall via an expandable member wound around a second elongated body. This expandable member is typically made of a flexible polymer membrane with electrodes disposed on it. However, this membrane has poor rigidity after expansion and is easily deformed by pressure from the intestinal wall, resulting in poor circumferential adhesion to the intestinal wall. Therefore, when an electric field is applied to the intestinal tissue, it is difficult to accurately ablate the villi tissue of the intestine. Summary of the Invention

[0004] The purpose of this disclosure is to provide a novel device or system for ablation therapy of the digestive tract.

[0005] The purpose of this disclosure is also to provide a novel support frame for an apparatus for ablation treatment of the digestive tract.

[0006] This disclosure provides an apparatus for ablation therapy of the digestive tract, comprising: Slender inner guide rod; A slender central guide tube is sleeved on the inner guide rod, and the central guide tube is rotatably disposed relative to the inner guide rod; A slender outer conduit is sleeved on the middle conduit, and the middle conduit is rotatably disposed relative to the outer conduit; An expandable component surrounds the inner guide rod. The expandable component includes a support frame and a flexible electrode membrane. The expandable component has a radially decreasing contraction working state and a radially increasing expansion working state. The rear end of the support frame is connected to the central guide tube. The support frame has a deformable component, and the deformable component changes shape when the support frame changes between the contraction and expansion working states. The deformable component is made of a rigid elastic material, and the deformable component gives the support frame a radially outward elastic force that changes from the contraction to the expansion working state. The electrode membrane has multiple electrodes for receiving electrical signals. The electrode membrane is spirally wound around the support frame. The inner end of the electrode membrane is connected to the support frame, and the outer end of the electrode membrane is connected to the inner guide rod via a connector, or / and the outer end of the electrode membrane is connected to the outer guide tube via a connector.

[0007] In some embodiments, it further includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected middle conduit to rotate forward relative to the outer conduit, so that while the electrode membrane expands radially, the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected middle conduit to rotate in the opposite direction relative to the outer conduit, so that while the electrode membrane contracts radially, the electrode membrane also compresses the supporting frame to contract radially at the same time.

[0008] In some embodiments, the actuator is connected to the middle conduit and is used to drive the support frame to rotate relative to the outer conduit when the middle conduit rotates relative to the outer conduit.

[0009] In some embodiments, it further includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected outer conduit to rotate in the opposite direction relative to the middle conduit, so that while the electrode membrane expands radially, the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected outer conduit to rotate in the forward direction relative to the middle conduit, so that while the electrode membrane contracts radially, the electrode membrane also compresses the supporting frame to contract radially in sync.

[0010] In some embodiments, the actuator is connected to the outer conduit and is used to drive the connector to rotate around the support frame when the outer conduit rotates relative to the middle conduit.

[0011] In some embodiments, the support frame has a front end and a rear end, the front end of the support frame is sleeved on the inner guide rod, the front end of the support frame and the inner guide rod are slidable in the front-back direction and rotatable in the circumferential direction, and the rear end of the support frame is connected to the middle guide tube.

[0012] In some embodiments, the support frame has a front end and a rear end. The front end of the support frame is sleeved on the inner guide rod. The front end of the support frame and the inner guide rod are slidable in the front-back direction and non-rotatable in the circumferential direction. The rear end of the support frame is connected to the middle guide tube.

[0013] In some embodiments, the support frame has a front end and a rear end, the front end of the support frame is sleeved on the inner guide rod, the front end of the support frame and the inner guide rod are rotatably and positioned in the front-rear direction, and the rear end of the support frame is connected to the central guide tube.

[0014] In some embodiments, the support frame has a front connecting ring forming the front end of the support frame. The front connecting ring is sleeved on the inner guide rod and is slidably disposed relative to the inner guide rod in the front-rear direction and rotatably disposed in the circumferential direction. The rear end of the support frame is connected to the middle guide rod; and / or, the front middle portion of the support frame is pivotally connected to the front connecting ring, and the pivot of the pivot connection is perpendicular to the inner guide rod.

[0015] In some embodiments, the support frame has a front connecting ring forming the front end of the support frame. The front connecting ring is sleeved on the inner guide rod and is configured to allow sliding in the front-rear direction but prohibit rotation in the circumferential direction relative to the inner guide rod. The rear end of the support frame is connected to the middle guide rod; and / or, the front middle portion of the support frame is pivotally connected to the front connecting ring, and the pivot connection is perpendicular to the inner guide rod.

[0016] In some embodiments, the support frame has a front connecting ring forming the front end of the support frame, the front connecting ring being sleeved on the inner guide rod, the front connecting ring being rotatably and positionally disposed on the inner guide rod in the front-rear direction, the rear end of the support frame being connected to the middle guide rod; and / or, the front middle portion of the support frame is pivotally connected to the front connecting ring, the pivot being perpendicular to the inner guide rod.

[0017] In some embodiments, the rear end of the support frame is fixedly connected to the central conduit; or, the rear end of the support frame is pivotally connected to the central conduit, and the pivot is perpendicular to the central conduit.

[0018] In some embodiments, the rear end of the support frame is sleeved on the central guide tube, and the rear end of the support frame and the central guide tube are slidably connected in the front-back direction but cannot be rotated relative to each other.

[0019] In some embodiments, the support frame has a rear connecting ring, which forms the rear end of the support frame. The rear connecting ring is sleeved on the middle guide tube, and the rear connecting ring and the middle guide tube are slidably connected in the front-rear direction but not rotatably relative to each other; and / or, the rear middle part of the support frame is pivotally connected to the rear connecting ring, and the pivot of the pivot connection is perpendicular to the inner guide rod.

[0020] In some embodiments, the front end of the support frame is a front connecting ring, which is sleeved on the inner guide rod; the rear end of the support frame is a rear connecting ring, which is sleeved on the middle guide tube.

[0021] In some embodiments, the connection between the rear end of the support frame and the central conduit is configured to restrict circumferential rotation of the rear end of the support frame relative to the central conduit.

[0022] In some embodiments, the connection between the outer end of the electrode membrane and the outer conduit is configured to restrict the outer end of the electrode membrane from rotating circumferentially relative to the outer conduit.

[0023] In some embodiments, the inner guide rod is fixedly disposed with the outer guide tube, and a front guide cap is fixedly connected to the front end of the inner guide rod. The inner guide rod is a tubular body with a guide wire cavity, and the center of the front guide cap also has a guide wire cavity and communicates with the guide wire cavity of the inner guide rod.

[0024] In some embodiments, the connector includes an electrode membrane connector and a deformable connector that is rigid and deformable in the circumferential direction. The electrode membrane connector is parallel to the inner guide rod and connected to the outer end of the electrode membrane. One end of the deformable connector is connected to the electrode membrane connector, and the other end of the deformable connector is connected to the outer conduit and / or the inner guide rod. During the transition of the support frame from a contracted working state to an expanded working state, the electrode membrane connector gradually moves away from the inner guide rod; during the transition of the support frame from an expanded working state to a contracted working state, the electrode membrane connector gradually moves closer to the inner guide rod.

[0025] In some embodiments, the deformable connector and the electrode film connector are selected from the following connection structures: pivot connection, fixed connection, slidably connected in the front-rear direction, and pivotally and slidably connected, wherein the pivot of the pivotal connection is perpendicular to the inner guide rod; the deformable connector and the outer guide tube and / or inner guide rod are selected from the following connection structures: pivot connection, fixed connection, slidably connected in the front-rear direction, and pivotally and slidably connected, wherein the pivot of the pivotal connection is perpendicular to the inner guide rod.

[0026] In some embodiments, when the support frame changes between a contracted working state and an expanded working state, the distance between the front and rear ends of the deformable connector can be variably set.

[0027] In some embodiments, the deformable connector is a rigid elastic sheet with elasticity, and the deformable connector is bent when the support frame is in a contracted working state.

[0028] In some embodiments, the deformable connector includes multiple sections of rod, with the ends of two adjacent sections pivotally connected to form a chain, an inner guide rod and / or an outer guide rod pivotally connected to an adjacent section of rod, and an electrode film connector pivotally connected to an adjacent section of rod, with the centerline of each pivot being spatially perpendicular to the inner guide rod.

[0029] In some embodiments, the deformable connector includes multiple sections of rod, which are slidably connected to form a telescopic rod. The electrode film connector is pivotally connected to the end of an adjacent section of rod, and the outer guide tube and / or inner guide rod are pivotally connected to an adjacent section of rod. The axis of each pivot is spatially perpendicular to the inner guide rod.

[0030] In some embodiments, the deformable connector includes a deformable connector located at the front of the electrode film connector and a deformable connector located at the rear of the electrode film connector; the rear end of the deformable connector located at the front of the electrode film connector is connected to the front end of the electrode film connector, and the front end of the deformable connector located at the front of the electrode film connector is connected to the inner guide rod; the front end of the deformable connector located at the rear of the electrode film connector is connected to the rear end of the electrode film connector, and the rear end of the deformable connector located at the rear of the electrode film connector is connected to the outer conduit.

[0031] In some embodiments, the inner guide rod and the middle guide tube are fixedly positioned relative to each other in the front-back direction, and the outer guide tube and the middle guide tube are fixedly positioned relative to each other in the front-back direction.

[0032] In some embodiments, the support frame includes an inner support frame and multiple outer support rods connected to the inner support frame. The outer support rods are parallel to the central guide tube. The multiple outer support rods are distributed in a cylindrical pattern around the inner support frame. The inner end of the electrode membrane is connected to one of the outer support rods.

[0033] In some embodiments, the length of the electrode film in the front-back direction is greater than or equal to the length of the outer support rod in the front-back direction, and the length difference between the two is less than 2 mm.

[0034] In some embodiments, when the support frame is in a contracted working state, the electrode membrane is wound around the support frame in multiple turns; when the support frame is in an expanded working state, the number of turns of the electrode membrane is greater than 1 turn and less than 2 turns.

[0035] In some embodiments, when the distance between the front end of the support frame and the rear end of the support frame changes, the support frame switches between a contracted working state and an expanded working state.

[0036] In some embodiments, the electrode film is clamped to the support frame, such that the innermost ring of the electrode film is always in close contact with the support frame, and the electrode films of adjacent rings are always in close contact with each other.

[0037] In some embodiments, the support frame includes an inner support frame and multiple outer support rods. The inner support frame includes multiple inner support rods. Each inner support rod has a front connecting ring fixed or pivotally connected to its front middle portion, forming the front end of the support frame. Each inner support rod has a rear connecting ring fixed or pivotally connected to its rear middle portion, forming the rear end of the support frame. The middle section of each inner support rod is fixedly connected to an outer support rod. Each outer support rod is parallel to the central guide tube, and the multiple outer support rods are distributed in a cylindrical, spaced-apart pattern around the inner support rods. Each outer support rod has a front extension section extending forward of the middle section of the inner support rod, and / or a rear extension section extending backward of the middle section of the inner support rod, such that the length of the outer support rod in the front-rear direction is greater than the length of the middle section of the inner support rod in the front-rear direction. When the support frame is in an expanded working state, the inner support rods are in an inward-facing arc shape; when the support frame is in a contracted working state, the inner support rods are approximately straight.

[0038] In some embodiments, when the support frame is in an expanded working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0039] In some embodiments, the support frame includes an inner support frame, a middle support frame, and multiple outer support rods parallel to the middle guide tube. A front connecting ring is fixed or pivotally connected to the front middle portion of the inner support frame, forming the front end of the support frame. A rear connecting ring is fixed or pivotally connected to the rear middle portion of the inner support frame, forming the rear end of the support frame. The inner support frame includes multiple inner support rods, and the middle support frame includes multiple middle support rods. When the support frame is in an expanded working state, the inner support rods are in an inward-facing arc shape, and the middle support rods are in an outward-facing arc shape. Each of the... The middle section of the central support rod is fixedly connected to the middle section of each of the inner support rods. When the support frame is in the retracted working state, the central support rod and the inner support rods are generally straight. The front end and the rear end of the central support rod are respectively connected to the outer support rod. At least one of the two ends of the central support rod, the front end and the rear end, is slidably connected to the outer support rod in the front-back direction. The multiple outer support rods are distributed in a cylindrical interval around the central support rod. The length of the outer support rod in the front-back direction is greater than or equal to the length of the central support rod in the front-back direction.

[0040] In some embodiments, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the middle support rod in the front-rear direction, and the front end of the middle support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the middle support rod is located in front of or aligned with the rear end of the outer support rod; the length of the outer support rod in the front-rear direction is also greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0041] This disclosure also provides an apparatus for ablation therapy of the digestive tract, comprising: Slender central duct; A slender outer conduit is sleeved on the middle conduit, and the middle conduit is rotatably disposed relative to the outer conduit; An expandable component surrounds the central conduit. The expandable component includes a supporting frame and a flexible electrode membrane. The expandable component has a radially decreasing contraction working state and a radially increasing expansion working state. The supporting frame is connected to the central conduit and has a deformable component. When the supporting frame changes between the contraction and expansion working states, the deformable component changes shape. The deformable component is made of a rigid elastic material, and the deformable component gives the supporting frame a radially outward elastic force as it changes from the contraction to the expansion working state. The electrode membrane has multiple electrodes for receiving electrical signals. The electrode membrane is spirally wound around the supporting frame. The inner end of the electrode membrane is connected to the supporting frame, and the outer end of the electrode membrane is connected to the outer conduit via a connector.

[0042] In some embodiments, the connection between the rear end of the support frame and the central conduit is configured to restrict circumferential rotation of the rear end of the support frame relative to the central conduit.

[0043] In some embodiments, the connection between the outer end of the electrode membrane and the outer conduit is configured to restrict the outer end of the electrode membrane from rotating circumferentially relative to the outer conduit.

[0044] In some embodiments, it further includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected middle conduit to rotate forward relative to the outer conduit, so that while the electrode membrane expands radially, the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected middle conduit to rotate in the opposite direction relative to the outer conduit, so that while the electrode membrane contracts radially, the electrode membrane also compresses the supporting frame to contract radially.

[0045] In some embodiments, it further includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected outer conduit to rotate in the opposite direction relative to the middle conduit, so that while the electrode membrane expands radially, the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected outer conduit to rotate in the forward direction relative to the middle conduit, so that while the electrode membrane contracts radially, the electrode membrane also compresses the supporting frame to contract radially.

[0046] In some embodiments, the support frame includes multiple inner support rods and multiple outer support rods parallel to the central guide tube and connected to the ends of the inner support rods. The multiple outer support rods are distributed in a cylindrical shape around the central guide tube. The inner middle section of each inner support rod is fixedly connected to the central guide tube. At least one of the front and rear ends of the inner support rod is slidably connected to a corresponding outer support rod in the front-rear direction. When the support frame is in the expanded working state, the inner support rod is in an arc shape with its opening facing outward. When the support frame is in the contracted working state, the inner support rod is in a generally straight shape.

[0047] In some embodiments, the outer support rod has a front extension extending forward toward the front end of the inner support rod, and / or the outer support rod has a rear extension extending backward toward the rear end of the inner support rod, such that when the support frame is in a retracted working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0048] In some embodiments, the support frame includes multiple annular rods and multiple outer support rods parallel to the central guide tube. The inner side of each annular rod is fixedly connected to the central guide tube, and the outer side of each annular rod is fixedly connected to a corresponding outer support rod. When the support frame is in an expanded working state, the annular rods are open annular shapes, and when the support frame is in a contracted working state, the annular rods are flattened and approximately straight.

[0049] In some embodiments, the outer support rod has a front extension extending forward toward the outer side of the annular rod, and / or the outer support rod has a rear extension extending backward toward the outer side of the annular rod, such that when the support frame is in a retracted working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the annular rod in the front-rear direction, and the front end of the annular rod is located behind the front end of the outer support rod, or the front end of the annular rod is aligned with the front end of the outer support rod; the rear end of the annular rod is located in front of or aligned with the rear end of the outer support rod.

[0050] In some embodiments, the support frame includes multiple inner support rods and multiple outer support rods parallel to the central guide tube. The multiple outer support rods are distributed in a cylindrical shape around the central guide tube. The inner middle section of each inner support rod is fixedly connected to the central guide tube, and the two outer ends of each inner support rod are fixedly connected to a corresponding outer support rod. When the support frame is in the expanded working state, the front part of the inner support rod is an arc shape with the opening facing backward, and the rear part of the inner support rod is an arc shape with the opening facing forward. The inner support rods and the outer support rods form a closed ring. When the support frame is in the contracted working state, the ring is flattened.

[0051] In some embodiments, the outer support rod has a front extension extending forward toward the front end of the inner support rod, and / or the outer support rod has a rear extension extending backward toward the rear end of the inner support rod, such that when the support frame is in a retracted working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0052] In some embodiments, the support frame has two ends, a front end and a rear end, one end of the support frame is sleeved on the central guide tube, and the end is slidable in the front-rear direction and rotatable in the circumferential direction relative to the central guide tube, and the other end of the support frame is connected to the central guide tube.

[0053] In some embodiments, one end of the support frame is suspended, and the other end of the support frame is connected to the central conduit.

[0054] In some embodiments, the support frame has two ends, a front end and a rear end, one end of the support frame is sleeved on the central guide tube, and the end is slidably disposed with the central guide tube in the front-back direction but not rotatably relative to it, and the other end of the support frame is connected to the central guide tube.

[0055] In some embodiments, the support frame has two ends, a front end and a rear end, one end of the support frame is sleeved on the central guide tube, and the end is rotatably disposed with respect to the central guide tube in the circumferential direction but not in the front-back direction, and the other end of the support frame is connected to the central guide tube.

[0056] In some embodiments, the support frame has two ends, a front end and a rear end, one end of the support frame is fixedly disposed with the central guide tube, and the other end of the support frame is connected to the central guide tube.

[0057] In some embodiments, the support frame has two parts: a front middle part and a rear middle part. One part of the support frame is pivotally connected to a connecting ring, the pivot being perpendicular to the central guide tube. The connecting ring is sleeved on the central guide tube and is slidably disposed relative to the central guide tube in the front-back direction and rotatably disposed in the circumferential direction. The corresponding end of the other part of the support frame is connected to the central guide tube.

[0058] In some embodiments, the support frame has two parts: a front middle part and a rear middle part. One part of the support frame is pivotally connected to a connecting ring, the pivot being perpendicular to the central guide tube. The connecting ring is sleeved on the central guide tube and slides relative to the central guide tube in the front-back direction but is non-rotatable in the circumferential direction. The corresponding end of the other part of the support frame is connected to the central guide tube.

[0059] In some embodiments, the support frame has two parts: a front middle part and a rear middle part. One part of the support frame is pivotally connected to a connecting ring, the pivot being perpendicular to the central guide tube. The connecting ring is sleeved on the central guide tube and is rotatably arranged relative to the central guide tube in the circumferential direction and non-slip in the front-rear direction. The corresponding end of the other part of the support frame is connected to the central guide tube.

[0060] In some embodiments, the support frame has two parts, a front middle part and a rear middle part, one part of the support frame is pivotally connected to the central guide tube, the pivot of which is perpendicular to the central guide tube, and the other part of the support frame is connected to the central guide tube at the corresponding end.

[0061] In some embodiments, the end corresponding to another part of the supporting frame is fixedly connected to the central guide tube.

[0062] In some embodiments, the end corresponding to another part of the supporting frame is slidably connected to the central guide tube in the front-back direction but cannot be rotated relative to it.

[0063] In some embodiments, the end corresponding to another part of the support frame is slidably disposed relative to the central guide tube in the front-back direction and rotatably disposed in the circumferential direction.

[0064] In some embodiments, the end corresponding to another part of the support frame is rotatably disposed relative to the central guide tube in the circumferential direction and non-sliding in the front-rear direction.

[0065] In some embodiments, another part of the supporting frame is pivotally connected to another connecting ring, the pivot being perpendicular to the central guide tube, and the other connecting ring is sleeved on the central guide tube and fixedly connected to the central guide tube.

[0066] In some embodiments, another part of the supporting frame is pivotally connected to another connecting ring, the pivot being perpendicular to the central guide tube, and the other connecting ring is sleeved on the central guide tube and is rotatably disposed relative to the central guide tube in the circumferential direction but not slidable in the front-back direction.

[0067] In some embodiments, another part of the supporting frame is pivotally connected to another connecting ring, the pivot being perpendicular to the central guide tube, and the other connecting ring is sleeved on the central guide tube and is slidably disposed relative to the central guide tube in the front-back direction but not rotatably disposed relative to the central guide tube.

[0068] In some embodiments, another part of the supporting frame is pivotally connected to another connecting ring, the pivot being perpendicular to the central guide tube, and the other connecting ring is sleeved on the central guide tube and is slidably disposed relative to the central guide tube in the front-back direction and rotatably disposed in the circumferential direction.

[0069] In some embodiments, the connector includes an electrode membrane connector and a deformable connector that is rigid and deformable in the circumferential direction. The electrode membrane connector is parallel to the central guide tube and connected to the outer end of the electrode membrane. The front end of the deformable connector is connected to the rear end of the electrode membrane connector, and the rear end of the deformable connector is connected to the outer guide tube. During the process of the support frame changing from a contracted working state to an expanded working state, the electrode membrane connector gradually moves away from the central guide tube. During the process of the support frame changing from an expanded working state to a contracted working state, the electrode membrane connector gradually moves closer to the central guide tube.

[0070] In some embodiments, the front end of the deformable connector and the rear end of the electrode film connector are selected from the following connection structures: pivot connection, fixed connection, slidably connected in the front-rear direction, and pivotally and slidably connected, wherein the pivot of the pivotal connection is perpendicular to the middle conduit; the rear end of the deformable connector and the outer conduit are selected from the following connection structures: pivot connection, fixed connection, slidably connected in the front-rear direction, and pivotally and slidably connected, wherein the pivot of the pivotal connection is perpendicular to the middle conduit.

[0071] In some embodiments, when the support frame changes between a contracted working state and an expanded working state, the distance between the front and rear ends of the deformable connector can be variably set.

[0072] In some embodiments, the deformable connector is a rigid elastic sheet with elasticity, and the deformable connector is bent when the support frame is in a contracted working state.

[0073] In some embodiments, the deformable connector includes multiple sections of rod, with the ends of two adjacent sections pivotally connected to form a chain, the outer conduit pivotally connected to the rear end of an adjacent section of rod, and the rear end of the electrode film connector pivotally connected to the front end of an adjacent section of rod, with each pivot perpendicular to the middle conduit.

[0074] In some embodiments, the deformable connector includes multiple sections of rod, which are slidably connected to form a telescopic rod. The rear end of the electrode film connector is pivotally connected to the front end of an adjacent section of rod, and the outer conduit is pivotally connected to the rear end of an adjacent section of rod. The axis of each pivot is perpendicular to the middle conduit.

[0075] In some embodiments, it further includes an inner guide rod, the middle guide tube is sleeved on the inner guide rod, and the middle guide tube is rotatably disposed relative to the inner guide rod.

[0076] In some embodiments, the inner guide rod is fixedly disposed with the outer guide tube, and a front guide cap is fixedly connected to the front end of the inner guide rod. The inner guide rod is a tubular body with a guide wire cavity, and the center of the front guide cap also has a guide wire cavity and communicates with the guide wire cavity of the inner guide rod.

[0077] In some embodiments, the connector includes an electrode membrane connector and a deformable connector that is rigid and deformable in the circumferential direction. The electrode membrane connector is parallel to the inner guide rod and connected to the outer end of the electrode membrane. One end of the deformable connector is connected to the electrode membrane connector, and the other end of the deformable connector is connected to the outer conduit and / or the inner guide rod. During the transition of the support frame from a contracted working state to an expanded working state, the electrode membrane connector gradually moves away from the inner guide rod; during the transition of the support frame from an expanded working state to a contracted working state, the electrode membrane connector gradually moves closer to the inner guide rod.

[0078] In some embodiments, the deformable connector and the electrode film connector are selected from the following connection structures: pivot connection, fixed connection, slidably connected in the front-rear direction, and pivotally and slidably connected, wherein the pivot of the pivotal connection is perpendicular to the inner guide rod; the deformable connector and the outer guide tube and / or inner guide rod are selected from the following connection structures: pivot connection, fixed connection, slidably connected in the front-rear direction, and pivotally and slidably connected, wherein the pivot of the pivotal connection is perpendicular to the inner guide rod.

[0079] In some embodiments, when the support frame changes between a contracted working state and an expanded working state, the distance between the front and rear ends of the deformable connector can be variably set.

[0080] In some embodiments, the deformable connector is a rigid elastic sheet with elasticity, and the deformable connector is bent when the support frame is in a contracted working state.

[0081] In some embodiments, the deformable connector includes multiple sections of rod, with the ends of two adjacent sections pivotally connected to form a chain, an inner guide rod and / or an outer guide rod pivotally connected to an adjacent section of rod, and an electrode film connector pivotally connected to an adjacent section of rod, with the centerline of each pivot being spatially perpendicular to the inner guide rod.

[0082] In some embodiments, the deformable connector includes multiple sections of rod, which are slidably connected to form a telescopic rod. The electrode film connector is pivotally connected to the end of an adjacent section of rod, and the outer guide tube and / or inner guide rod are pivotally connected to an adjacent section of rod. The axis of each pivot is spatially perpendicular to the inner guide rod.

[0083] In some embodiments, the deformable connector includes a deformable connector located at the front of the electrode film connector and a deformable connector located at the rear of the electrode film connector; the rear end of the deformable connector located at the front of the electrode film connector is connected to the front end of the electrode film connector, and the front end of the deformable connector located at the front of the electrode film connector is connected to the inner guide rod; the front end of the deformable connector located at the rear of the electrode film connector is connected to the rear end of the electrode film connector, and the rear end of the deformable connector located at the rear of the electrode film connector is connected to the outer conduit.

[0084] In some embodiments, the inner guide rod and the middle guide tube are fixedly positioned relative to each other in the front-back direction, and the outer guide tube and the middle guide tube are fixedly positioned relative to each other in the front-back direction.

[0085] In some embodiments, the support frame includes an inner support frame and multiple outer support rods connected to the inner support frame. The outer support rods are parallel to the central guide tube. The multiple outer support rods are distributed in a cylindrical pattern around the inner support frame. The inner end of the electrode membrane is connected to one of the outer support rods.

[0086] In some embodiments, the length of the electrode film in the front-back direction is greater than or equal to the length of the outer support rod in the front-back direction, and the length difference between the two is less than 2 mm.

[0087] In some embodiments, when the support frame is in a contracted working state, the electrode membrane is wound around the support frame in multiple turns; when the support frame is in an expanded working state, the number of turns of the electrode membrane is greater than 1 turn and less than 2 turns.

[0088] In some embodiments, when the distance between the front end of the support frame and the rear end of the support frame changes, the support frame switches between a contracted working state and an expanded working state.

[0089] In some embodiments, the electrode film is clamped to the support frame, such that the innermost ring of the electrode film is always in close contact with the support frame, and the electrode films of adjacent rings are always in close contact with each other.

[0090] In some embodiments, the support frame includes an inner support frame and multiple outer support rods. The inner support frame includes multiple inner support rods. Each inner support rod has a front connecting ring fixed or pivotally connected to its front middle portion, forming the front end of the support frame. Each inner support rod has a rear connecting ring fixed or pivotally connected to its rear middle portion, forming the rear end of the support frame. The middle section of each inner support rod is fixedly connected to an outer support rod. Each outer support rod is parallel to the central guide tube, and the multiple outer support rods are distributed in a cylindrical, spaced-apart pattern around the inner support rods. Each outer support rod has a front extension section extending forward of the middle section of the inner support rod, and / or a rear extension section extending backward of the middle section of the inner support rod, such that the length of the outer support rod in the front-rear direction is greater than the length of the middle section of the inner support rod in the front-rear direction. When the support frame is in an expanded working state, the inner support rods are in an inward-facing arc shape; when the support frame is in a contracted working state, the inner support rods are approximately straight.

[0091] In some embodiments, when the support frame is in an expanded working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0092] In some embodiments, the support frame includes an inner support frame, a middle support frame, and multiple outer support rods parallel to the middle guide tube. A front connecting ring is fixed or pivotally connected to the front middle portion of the inner support frame, forming the front end of the support frame. A rear connecting ring is fixed or pivotally connected to the rear middle portion of the inner support frame, forming the rear end of the support frame. The inner support frame includes multiple inner support rods, and the middle support frame includes multiple middle support rods. When the support frame is in an expanded working state, the inner support rods are in an inward-facing arc shape, and the middle support rods are in an outward-facing arc shape. Each of the... The middle section of the central support rod is fixedly connected to the middle section of each of the inner support rods. When the support frame is in the retracted working state, the central support rod and the inner support rods are generally straight. The front end and the rear end of the central support rod are respectively connected to the outer support rod. At least one of the two ends of the central support rod, the front end and the rear end, is slidably connected to the outer support rod in the front-back direction. The multiple outer support rods are distributed in a cylindrical interval around the central support rod. The length of the outer support rod in the front-back direction is greater than or equal to the length of the central support rod in the front-back direction.

[0093] In some embodiments, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the middle support rod in the front-rear direction, and the front end of the middle support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the middle support rod is located in front of or aligned with the rear end of the outer support rod; the length of the outer support rod in the front-rear direction is also greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0094] This disclosure also provides an apparatus for ablation therapy of the digestive tract, comprising: Slender inner guide rod; A slender central guide tube, which is sleeved on the outside of the inner guide rod; A slender outer conduit is sleeved on the outside of the middle conduit. Among the three components—inner guide rod, middle conduit, and outer conduit—at least one component is defined as a reference component, and at least one other component is defined as a rotating component. The defined rotating component is rotatably arranged relative to the defined reference component. A connector having a first connecting portion and a second connecting portion, wherein the distance between the first connecting portion and the second connecting portion is variably set; An expandable component, having a radially decreasing contraction working state and a radially increasing expansion working state, the expandable component comprising: A support frame is connected to a defined rotating component. The support frame has a deformable component. The deformable component has an elastic force that causes the support frame to tend to expand radially. When the expandable component is in a contracted working state, the support frame is also in a radially shrinking contracted working state. When the expandable component is in an expanding working state, the support frame is also in a radially expanding expanding working state. An electrode membrane is provided with electrodes for receiving electrical signals. The electrode membrane is wound around the outside of the support frame, and its inner end is connected to the support frame. At least one of the defined reference components is connected to a first connection portion of the connector, and the outer end of the electrode membrane is connected to a second connection portion of the connector. When the expandable component is in a contracted working state, the electrode membrane is also in a radially shrinking contracted working state; when the expandable component is in an expanded working state, the electrode membrane is also in a radially expanding expanded working state. If the defined rotating component rotates relative to the defined reference component, the defined rotating component drives the support frame to rotate relative to the defined reference component, and then the inner end of the electrode film rotates relative to the outer end of the electrode film. The deformable component undergoes elastic deformation so that the support frame abuts against the inner side of the electrode film, and the expandable component switches between a contracted working state and an expanded working state.

[0095] In some embodiments, at least a portion of the expandable component surrounds the outside of the inner guide rod.

[0096] In some embodiments, the support frame has two ends, one end of the support frame and the other end of the support frame. If the expandable component switches between a contracted working state and an expanded working state, the two ends of the support frame undergo relative displacement in the front-rear direction.

[0097] In some embodiments, the support frame includes multiple outer support rods and an inner support frame connected to the outer support rods, wherein one of the outer support rods is connected to the inner end of the electrode membrane, the inner support frame is configured with the deformable member, and the outer support rods abut against the inner side of the electrode membrane. If the expandable member is in an expanded working state, the multiple outer support rods surround the outer side of the inner support frame.

[0098] In some embodiments, one end of the support frame is one end of the inner support frame, and the other end of the support frame is the other end of the inner support frame.

[0099] In some embodiments, if the expandable component is in an expanded working state, the multiple outer support rods are parallel to the central guide tube.

[0100] In some embodiments, a rear connecting ring is pivotally connected to the rear middle portion of the support frame, the pivot being perpendicular to the central guide tube, and the rear connecting ring being the rear end of the support frame.

[0101] In some embodiments, the front middle portion of the support frame is pivotally connected to a front connecting ring, the pivot being perpendicular to the central guide tube, and the front connecting ring being the front end of the support frame.

[0102] In some embodiments, the support frame has one end and another end. The distance between one end of the support frame and the defined reference component is selected from one of the following arrangements: The configuration can be slidable in the front-back direction and rotatable in the circumferential direction, slidable in the front-back direction and non-rotatable in the circumferential direction, rotatable and positioned in the front-back direction, fixed, or pivotally connected, wherein the pivot of the pivotally connected configuration is perpendicular to the reference component. The other end of the support frame and the defined rotating component are selected from one of the following arrangements: The configuration can be slidable in the front-to-back direction and rotatable in the circumferential direction, slidable in the front-to-back direction and non-rotatable in the circumferential direction, rotatable and positioned in the front-to-back direction, fixed, or pivotally connected, wherein the pivot of the pivotally connected component is perpendicular to the rotating component.

[0103] In some embodiments, the connector includes an electrode film connector and a deformable connector that is rigid and deformable in the circumferential direction. The electrode film connector is connected to the deformable connector. The electrode film connector is connected to the outer end of the electrode film and forms a second connection portion of the connector. The deformable connector is also connected to the at least one defined reference member to form a first connection portion of the connector. During the process of the expandable member changing from a contracted working state to an expanded working state, the electrode film connector gradually moves away from the inner guide rod. During the process of the expandable member changing from an expanded working state to a contracted working state, the electrode film connector gradually moves closer to the inner guide rod.

[0104] In some embodiments, the connection between one end of the deformable connector and the electrode film connector is selected from one of the following connection structures: pivot connection, fixed connection, slidable connection, and pivotal and slidable connection, wherein the pivot is perpendicular to the central conduit. The connection between the other end of the deformable connector and the defined reference component is selected from one of the following connection structures: pivot connection, fixed connection, slidable connection, and pivotal and slidable connection, wherein the pivot is perpendicular to the central guide tube.

[0105] In some embodiments, the distance between the two ends of the deformable connector is variably set when the expandable component changes between a contracted working state and an expanded working state.

[0106] In some embodiments, the deformable connector is a rigid component with deformability, and the deformable connector is bent when the expandable component is in a contracted working state.

[0107] In some embodiments, the deformable connector includes multiple sections of rod, which are pivotally connected and / or slidably connected to each other, wherein the pivot of the pivotal connection is perpendicular to the central guide tube.

[0108] In some embodiments, the electrode membrane connector is parallel to the central conduit.

[0109] In some embodiments, the outer conduit and inner guide rod are both defined as reference components, the inner guide rod is circumferentially fixed to the outer conduit, and the middle conduit is defined as a rotating component; the middle conduit is rotatably disposed relative to the outer conduit and inner guide rod; the support frame is connected to the middle conduit, and the first connecting portion of the connector is connected to the outer conduit or the inner guide rod.

[0110] In some embodiments, a first connecting portion of the connector is connected to the inner guide rod and the outer conduit, respectively, and the connector is configured to restrict the outer end of the electrode membrane from rotating circumferentially relative to the inner guide rod and the outer conduit.

[0111] In some embodiments, the outer guide tube and the inner guide rod are fixedly disposed or slidably disposed in the front-to-back direction.

[0112] In some embodiments, one end of the support frame is the front end of the support frame, and the other end of the support frame is the rear end of the support frame. The front end of the support frame is sleeved on the outside of the inner guide rod, and the rear end of the support frame is connected to the middle guide tube.

[0113] In some embodiments, one end of the deformable connector is connected to the outer guide tube or the inner guide rod.

[0114] In some embodiments, the electrode film connector is parallel to the inner guide rod.

[0115] In some embodiments, one end of the deformable connector is connected to the external conduit.

[0116] In some embodiments, the electrode membrane connector is parallel to the central conduit.

[0117] In some embodiments, the inner guide rod is a tubular body with a guide wire cavity, and the tubular body is defined as an inner tube.

[0118] In some embodiments, the electrode membrane is spirally wound around the outside of the support frame. During the transition from the contracted working state to the expanded working state, the diameter of the outermost electrode membrane gradually increases, and the total number of turns of the electrode membrane gradually decreases; conversely, during the transition from the expanded working state to the contracted working state, the diameter of the outermost electrode membrane gradually decreases, and the total number of turns of the electrode membrane gradually increases.

[0119] In some embodiments, the support frame includes multiple outer support rods and an inner support frame connected to the outer support rods. Each outer support rod and the corresponding inner support frame constitute a linkage mechanism. The inner support frame includes multiple first connecting rods, multiple second connecting rods, a front connecting ring at the front, and a rear connecting ring at the rear. At least one linkage mechanism is an X-type linkage mechanism. In the X-type linkage mechanism, the rear end of the first connecting rod is fixedly connected to the rear of the outer support rod, and the front end of the first connecting rod is fixedly connected to the front connecting ring. The front end of the second connecting rod... The end of the first link is fixedly connected to the front part of the outer support rod, and the rear end of the second link is fixedly connected to the rear connecting ring. At least one of the four parts of the first link, the first link, the second link, and the second link constitutes the deformable component, or all four parts of the first link, the first link, the second link, and the second link constitute the deformable component. When the expandable component is in the expanding working state, the first link and the second link intersect and there is no rotating pivot for connection at the intersection point.

[0120] In some embodiments, all of the aforementioned linkage mechanisms are X-type linkage mechanisms, wherein the rear end of the first linkage is fixedly connected to the rear end of the outer support rod, and the front end of the second linkage is fixedly connected to the front end of the outer support rod.

[0121] In some embodiments, the width of both ends of the outer support rod is greater than the width of the rear end of the first connecting rod connected thereto and the width of the front end of the second connecting rod connected thereto.

[0122] In some embodiments, the width of the rear portion of the first link is smaller than the width of the middle portion of the first link, and the width of the front portion of the first link is smaller than the width of the middle portion of the first link; and / or, The width of the rear part of the second link is smaller than the width of the middle part of the second link, and the width of the front part of the second link is smaller than the width of the middle part of the second link.

[0123] In some embodiments, the width of the rear part of the outer support rod is greater than the width of the middle part of the outer support rod, the width of the front part of the outer support rod is greater than the width of the middle part of the outer support rod, and through holes for fixing the inner end of the electrode film are respectively provided at both ends of the outer support rod.

[0124] In some embodiments, it further includes an actuator connected to the rotating component, the actuator being used to drive the rotating component to rotate relative to the reference component.

[0125] In some embodiments, the connection between the support frame and the defined rotating component is configured to restrict the support frame from rotating in the circumferential direction relative to the defined rotating component.

[0126] In some embodiments, the connector is configured to restrict the outer end of the electrode film from rotating circumferentially relative to the defined reference member.

[0127] This disclosure also provides an apparatus for ablation therapy of the digestive tract, comprising: Slender central duct; A slender outer conduit is sleeved on the outside of the middle conduit. Of the two components, the middle conduit and the outer conduit, one component is defined as a reference component and the other component is defined as a rotating component. The defined rotating component is rotatably arranged relative to the defined reference component. A connector having a first connecting portion and a second connecting portion, wherein the distance between the first connecting portion and the second connecting portion is variably set; An expandable component, having a radially decreasing contraction working state and a radially increasing expansion working state, the expandable component comprising: A support frame is connected to a defined rotating component. The support frame has a deformable component. The deformable component has an elastic force that causes the support frame to tend to expand radially. When the expandable component is in a contracted working state, the support frame is also in a radially shrinking contracted working state. When the expandable component is in an expanding working state, the support frame is also in a radially expanding expanding working state. An electrode membrane is provided with electrodes for receiving electrical signals. The electrode membrane is wound around the outside of the support frame, and its inner end is connected to the support frame. The defined reference component is connected to the first connection portion of the connector, and the outer end of the electrode membrane is connected to the second connection portion of the connector. When the expandable component is in a contracted working state, the electrode membrane is also in a radially shrinking contracted working state; when the expandable component is in an expanded working state, the electrode membrane is also in a radially expanding expanded working state. If the defined rotating component rotates relative to the defined reference component, the defined rotating component drives the support frame to rotate relative to the defined reference component, and then the inner end of the electrode film rotates relative to the outer end of the electrode film. The deformable component undergoes elastic deformation so that the support frame abuts against the inner side of the electrode film, and the expandable component switches between a contracted working state and an expanded working state.

[0128] In some embodiments, at least a portion of the expandable component surrounds the outer side of the central conduit.

[0129] In some embodiments, the support frame has two ends, one end of the support frame and the other end of the support frame. If the expandable component switches between a contracted working state and an expanded working state, the two ends of the support frame undergo relative displacement in the front-rear direction.

[0130] In some embodiments, the support frame includes multiple outer support rods and an inner support frame connected to the outer support rods, wherein one of the outer support rods is connected to the inner end of the electrode membrane, the inner support frame is configured with the deformable member, and the outer support rods abut against the inner side of the electrode membrane. If the expandable member is in an expanded working state, the multiple outer support rods surround the outer side of the inner support frame.

[0131] In some embodiments, one end of the support frame is one end of the inner support frame, and the other end of the support frame is the other end of the inner support frame.

[0132] In some embodiments, if the expandable component is in an expanded working state, the multiple outer support rods are parallel to the central guide tube.

[0133] In some embodiments, a rear connecting ring is pivotally connected to the rear middle portion of the support frame, the pivot being perpendicular to the central guide tube, and the rear connecting ring being the rear end of the support frame.

[0134] In some embodiments, the front middle portion of the support frame is pivotally connected to a front connecting ring, the pivot being perpendicular to the central guide tube, and the front connecting ring being the front end of the support frame.

[0135] In some embodiments, the support frame has one end and another end. The distance between one end of the support frame and the defined reference component is selected from one of the following arrangements: The configuration can be slidable in the front-back direction and rotatable in the circumferential direction, slidable in the front-back direction and non-rotatable in the circumferential direction, rotatable and positioned in the front-back direction, fixed, or pivotally connected, wherein the pivot of the pivotally connected configuration is perpendicular to the reference component. The other end of the support frame and the defined rotating component are selected from one of the following arrangements: The configuration can be slidable in the front-to-back direction and rotatable in the circumferential direction, slidable in the front-to-back direction and non-rotatable in the circumferential direction, rotatable and positioned in the front-to-back direction, fixed, or pivotally connected, wherein the pivot of the pivotally connected component is perpendicular to the rotating component.

[0136] In some embodiments, the connector includes an electrode film connector and a deformable connector that is rigid and deformable in the circumferential direction. The electrode film connector is connected to the deformable connector. The electrode film connector is connected to the outer end of the electrode film and forms a second connection portion of the connector. The deformable connector is also connected to the defined reference member to form a first connection portion of the connector. During the process of the expandable member changing from a contracted working state to an expanded working state, the electrode film connector gradually moves away from the central guide tube. During the process of the expandable member changing from an expanded working state to a contracted working state, the electrode film connector gradually moves closer to the central guide tube.

[0137] In some embodiments, the connection between one end of the deformable connector and the electrode film connector is selected from one of the following connection structures: pivot connection, fixed connection, slidable connection, and pivotal and slidable connection, wherein the pivot is perpendicular to the central conduit. The connection between the other end of the deformable connector and the defined reference component is selected from one of the following connection structures: pivot connection, fixed connection, slidable connection, and pivotal and slidable connection, wherein the pivot is perpendicular to the central guide tube.

[0138] In some embodiments, the distance between the two ends of the deformable connector is variably set when the expandable component changes between a contracted working state and an expanded working state.

[0139] In some embodiments, the deformable connector is a rigid component with deformability, and the deformable connector is bent when the expandable component is in a contracted working state.

[0140] In some embodiments, the deformable connector includes multiple sections of rod, which are pivotally connected and / or slidably connected to each other, wherein the pivot of the pivotal connection is perpendicular to the central guide tube.

[0141] In some embodiments, the electrode membrane connector is parallel to the central conduit.

[0142] In some embodiments, one end of the deformable connector is connected to the external conduit.

[0143] In some embodiments, the electrode membrane connector is parallel to the central conduit.

[0144] In some embodiments, the electrode membrane is spirally wound around the outside of the support frame. During the transition from the contracted working state to the expanded working state, the diameter of the outermost electrode membrane gradually increases, and the total number of turns of the electrode membrane gradually decreases; conversely, during the transition from the expanded working state to the contracted working state, the diameter of the outermost electrode membrane gradually decreases, and the total number of turns of the electrode membrane gradually increases.

[0145] In some embodiments, the support frame includes multiple outer support rods and an inner support frame connected to the outer support rods. Each outer support rod and the corresponding inner support frame constitute a linkage mechanism. The inner support frame includes multiple first connecting rods, multiple second connecting rods, a front connecting ring at the front, and a rear connecting ring at the rear. At least one linkage mechanism is an X-type linkage mechanism. In the X-type linkage mechanism, the rear end of the first connecting rod is fixedly connected to the rear of the outer support rod, and the front end of the first connecting rod is fixedly connected to the front connecting ring. The front end of the second connecting rod... The end of the first link is fixedly connected to the front part of the outer support rod, and the rear end of the second link is fixedly connected to the rear connecting ring. At least one of the four parts of the first link, the first link, the second link, and the second link constitutes the deformable component, or all four parts of the first link, the first link, the second link, and the second link constitute the deformable component. When the expandable component is in the expanding working state, the first link and the second link intersect and there is no rotating pivot for connection at the intersection point.

[0146] In some embodiments, all of the aforementioned linkage mechanisms are X-type linkage mechanisms, wherein the rear end of the first linkage is fixedly connected to the rear end of the outer support rod, and the front end of the second linkage is fixedly connected to the front end of the outer support rod.

[0147] In some embodiments, the width of both ends of the outer support rod is greater than the width of the rear end of the first connecting rod connected thereto and the width of the front end of the second connecting rod connected thereto.

[0148] In some embodiments, the width of the rear portion of the first link is smaller than the width of the middle portion of the first link, and the width of the front portion of the first link is smaller than the width of the middle portion of the first link; and / or, The width of the rear part of the second link is smaller than the width of the middle part of the second link, and the width of the front part of the second link is smaller than the width of the middle part of the second link.

[0149] In some embodiments, the width of the rear part of the outer support rod is greater than the width of the middle part of the outer support rod, the width of the front part of the outer support rod is greater than the width of the middle part of the outer support rod, and through holes for fixing the inner end of the electrode film are respectively provided at both ends of the outer support rod.

[0150] In some embodiments, it further includes an actuator connected to the rotating component, the actuator being used to drive the rotating component to rotate relative to the reference component.

[0151] In some embodiments, the connection between the support frame and the defined rotating component is configured to restrict the support frame from rotating in the circumferential direction relative to the defined rotating component.

[0152] In some embodiments, the connector is configured to restrict the outer end of the electrode film from rotating circumferentially relative to the defined reference member.

[0153] This disclosure also provides a support frame for an apparatus for ablation therapy of the digestive tract. The support frame has a radially contracting working state and a radially expanding working state. The support frame includes multiple outer support rods and an inner support frame connected to the outer support rods. The inner support frame includes multiple first connecting rods, multiple second connecting rods, a front connecting ring at the front, and a rear connecting ring at the rear. The multiple linkage mechanisms of the support frame include at least one X-shaped linkage mechanism. In the X-shaped linkage mechanism, the rear end of the first connecting rod is fixedly connected to the rear end of the outer support rod. The front end of a first connecting rod is fixedly connected to the front connecting ring, the front end of a second connecting rod is fixedly connected to the front of the outer support rod, and the rear end of the second connecting rod is fixedly connected to the rear connecting ring. At least one of the four components—the front and rear of the first connecting rod, the front and rear of the second connecting rod, and the rear of the second connecting rod—constitutes a deformable component; or, all four components constitute deformable components. The deformable component has an elastic force that causes the support frame to tend to expand radially. In some embodiments, when the support frame is in an expanded working state, the first and second connecting rods intersect and there is no rotating pivot at the intersection point.

[0154] In some embodiments, all of the aforementioned linkage mechanisms are X-type linkage mechanisms, wherein the rear end of the first linkage is fixedly connected to the rear end of the outer support rod, and the front end of the second linkage is fixedly connected to the front end of the outer support rod.

[0155] In some embodiments, the width of both ends of the outer support rod is greater than the width of the rear end of the first connecting rod connected thereto and the width of the front end of the second connecting rod connected thereto.

[0156] In some embodiments, the width of the rear portion of the first link is smaller than the width of the middle portion of the first link, and the width of the front portion of the first link is smaller than the width of the middle portion of the first link; and / or, The width of the rear part of the second link is smaller than the width of the middle part of the second link, and the width of the front part of the second link is smaller than the width of the middle part of the second link.

[0157] In some embodiments, the width of the rear part of the outer support rod is greater than the width of the middle part of the outer support rod, the width of the front part of the outer support rod is greater than the width of the middle part of the outer support rod, and through holes for fixing the inner end of the electrode film are respectively provided at both ends of the outer support rod.

[0158] This disclosure also provides a method for preparing a support frame for the device for ablation therapy of the digestive tract as described above, comprising the following preparation steps: S1. The pipe is cut through to form the front connecting ring, the rear connecting ring, and multiple sets of first connecting rods, outer support rods and second connecting rods disposed between the front connecting ring and the rear connecting ring. The two ends of the outer support rod are respectively adjacent to and spaced apart from the front connecting ring and the rear connecting ring. S2. The cut pipe is heated and shaped in the expansion working state, so that the deformable component has the elastic force in the contraction working state after the shaped support frame is formed.

[0159] In some embodiments, after step S2, the support frame is converted to a retractable working state, restoring the shape of the cut pipe.

[0160] This disclosure also provides a system for ablation therapy of the digestive tract, comprising the aforementioned apparatus for ablation therapy of the digestive tract, and further comprising: a signal generator configured to generate an electrical signal of electric field energy, the signal generator being electrically connected to the electrodes.

[0161] An apparatus for ablation therapy of the human duodenum, comprising the aforementioned apparatus for ablation therapy of the digestive tract.

[0162] The use of the aforementioned device for ablation treatment of the human duodenum in the treatment of type 2 diabetes.

[0163] A method for treating type 2 diabetes involves using the aforementioned device for ablation treatment of the human duodenum. After delivering the expandable component in a contracted working state to the target location, a supporting frame is rotated relative to the outer end of the electrode membrane via a rotating component. This causes the wound electrode membrane to expand radially, and the supporting frame also expands radially under the action of a rigid elastic material until the desired expansion working state is achieved. Ablation treatment of the human duodenum is then performed through the electrodes on the electrode membrane.

[0164] In some embodiments, after treatment, the support frame is rotated again by the rotating component, causing the wound electrode membrane to contract radially. The electrode membrane also compresses the support frame to contract radially at the same time until the contraction working state is reached; the expandable component is then removed from the human body from the target position.

[0165] The use of the aforementioned device for ablation treatment of the human duodenum in the treatment of obesity.

[0166] A method for treating obesity involves using the aforementioned device for ablation treatment of the human duodenum. After delivering the expandable component in a contracted working state to the target location, a supporting frame is rotated relative to the outer end of the electrode membrane via a rotating component. This causes the wound electrode membrane to expand radially, and the supporting frame also expands radially under the action of a rigid elastic material until the desired expansion working state is achieved. Ablation treatment of the human duodenum is then performed through the electrodes on the electrode membrane.

[0167] In some embodiments, after treatment, the support frame is rotated again by the rotating component, causing the wound electrode membrane to contract radially. The electrode membrane also compresses the support frame to contract radially at the same time until the contraction working state is reached; the expandable component is then removed from the human body from the target position.

[0168] The use of the aforementioned device for ablation therapy of the human duodenum in the treatment of non-alcoholic fatty liver disease.

[0169] A method for treating non-alcoholic fatty liver disease involves using the aforementioned device for ablation treatment of the human duodenum. After delivering the expandable component in a contracted working state to the target location, a supporting frame is rotated relative to the outer end of the electrode membrane via a rotating component. This causes the wound electrode membrane to expand radially, and the supporting frame also expands radially under the action of a rigid elastic material until the desired expansion working state is achieved. Ablation treatment of the human duodenum is then performed through the electrodes on the electrode membrane.

[0170] In some embodiments, after treatment, the support frame is rotated again by the rotating component, causing the wound electrode membrane to contract radially. The electrode membrane also compresses the support frame to contract radially at the same time until the contraction working state is reached; the expandable component is then removed from the human body from the target position.

[0171] Another technical solution disclosed herein is a device for ablation therapy of the digestive tract, comprising: Slender inner guide rod; A slender central guide tube is sleeved on the inner guide rod, and the central guide tube is rotatably disposed relative to the inner guide rod; A slender outer conduit is sleeved on the middle conduit, and the middle conduit is rotatably disposed relative to the outer conduit; An expandable component surrounds the inner guide rod. The expandable component includes a support frame and a flexible electrode membrane. The expandable component has a radially decreasing contraction working state and a radially increasing expansion working state. The rear end of the support frame is connected to the central guide tube. The deformable component of the support frame during the transition between the contraction and expansion working states is made of a rigid elastic material. This rigid elastic material gives the support frame a radially outward elastic force during the transition from the contraction to the expansion working state. The electrode membrane has multiple electrodes for receiving electrical signals. The electrode membrane is spirally wound around the support frame. The inner end of the electrode membrane is connected to the support frame, and the outer end of the electrode membrane is connected to the inner guide rod via a connector, or / and the outer end of the electrode membrane is connected to the outer guide tube via a connector.

[0172] Alternatively, the device further includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected middle guide tube to rotate in the forward direction relative to the outer guide tube, so that while the electrode membrane expands radially, the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected middle guide tube to rotate in the reverse direction relative to the outer guide tube, so that while the electrode membrane contracts radially, the electrode membrane also compresses the supporting frame to contract radially at the same time.

[0173] Alternatively, the actuator is connected to the middle conduit and is used to drive the support frame to rotate relative to the outer conduit when the middle conduit rotates relative to the outer conduit.

[0174] Optionally, the device further includes: an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected outer conduit to rotate in the opposite direction relative to the middle conduit, so that while the electrode membrane expands radially, the supporting frame also expands radially under the action of the rigid elastic material; and during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected outer conduit to rotate in the forward direction relative to the middle conduit, so that while the electrode membrane contracts radially, the electrode membrane also compresses the supporting frame to contract radially at the same time.

[0175] Alternatively, the actuator is connected to the outer conduit and is used to drive the connector to rotate around the support frame when the outer conduit rotates relative to the middle conduit.

[0176] Alternatively, the support frame has a front end and a rear end, the front end of the support frame is sleeved on the inner guide rod, the front end of the support frame is a movable end that allows sliding in the front-back direction and rotation in the circumferential direction relative to the inner guide rod, and the rear end of the support frame is connected to the middle guide tube.

[0177] Alternatively, the support frame has a front end and a rear end, the front end of the support frame is sleeved on the inner guide rod, and the front end of the support frame is configured to allow sliding in the front-back direction but prohibit rotation in the circumferential direction relative to the inner guide rod, and the rear end of the support frame is connected to the middle guide tube.

[0178] Alternatively, the support frame has a front end and a rear end, the front end of the support frame is sleeved on the inner guide rod, the front end of the support frame is rotatably and positioned on the inner guide rod in the front-rear direction, and the rear end of the support frame is connected to the middle guide tube.

[0179] Alternatively, the support frame has a front end portion, the front end portion of which is pivotally connected to a front connecting ring, the pivot being perpendicular to the inner guide rod, the front connecting ring being sleeved on the inner guide rod, the front connecting ring being a movable end portion that allows sliding in the front-back direction and rotating in the circumferential direction relative to the inner guide rod, and the rear end portion of the support frame being connected to the middle guide tube.

[0180] Alternatively, the support frame has a front end, the front end of which is pivotally connected to a front connecting ring, the pivot being perpendicular to the inner guide rod, the front connecting ring being sleeved on the inner guide rod, the front connecting ring being configured to allow sliding in the front-back direction but prohibiting rotation in the circumferential direction relative to the inner guide rod, and the rear end of the support frame being connected to the middle guide tube.

[0181] Alternatively, the support frame has a front end portion, the front end portion of which is pivotally connected to a front connecting ring, the pivot being perpendicular to the inner guide rod, the front connecting ring being sleeved on the inner guide rod, the front connecting ring being rotatably and positionally positioned on the inner guide rod in the front-rear direction, and the rear end portion of the support frame being connected to the middle guide tube.

[0182] Alternatively, the rear end of the supporting frame is fixedly connected to the central guide tube.

[0183] Alternatively, the rear end of the support frame is sleeved on the central guide tube, and the rear end of the support frame and the central guide tube are connected in a way that allows sliding in the front-back direction but prohibits relative rotation.

[0184] Alternatively, the support frame has a rear end, the rear end of which is pivotally connected to a rear connecting ring. The pivot of the rear connecting ring is perpendicular to the inner guide rod. The rear connecting ring is sleeved on the middle guide tube, and the rear connecting ring and the middle guide tube are connected in a way that allows sliding in the front-back direction but prohibits relative rotation.

[0185] Alternatively, the front end of the support frame is pivotally connected to a front connecting ring, the pivot being perpendicular to the inner guide rod; the rear end of the support frame is pivotally connected to a rear connecting ring, the pivot also being perpendicular to the inner guide rod; the front connecting ring is sleeved on the inner guide rod, and the rear connecting ring is sleeved on the middle guide tube.

[0186] Alternatively, the inner guide rod is fixedly disposed with the outer guide tube, and a front guide cap is fixedly connected to the front end of the inner guide rod. The inner guide rod is a tubular body with a guide wire cavity, and the center of the front guide cap also has a guide wire cavity and communicates with the guide wire cavity of the inner guide rod.

[0187] Optionally, the connector includes an outer end rod and a connecting strip that is rigid in the circumferential direction. The outer end rod is parallel to the inner guide rod and connected to the outer end of the electrode membrane. One end of the connecting strip is connected to the outer end rod, and the other end of the connecting strip is connected to the outer guide tube and / or the inner guide rod. During the transition of the support frame from a contracted working state to an expanded working state, the outer end rod gradually moves away from the inner guide rod. During the transition of the support frame from an expanded working state to a contracted working state, the outer end rod gradually moves closer to the inner guide rod.

[0188] Alternatively, the connecting strip and the outer end rod are selected from the following three connection structures: pivot connection, fixed connection, and slidable connection in the front-back direction, wherein the pivot of the pivot connection is perpendicular to the inner guide rod; the connecting strip and the outer guide tube and / or inner guide rod are selected from the following three connection structures: pivot connection, fixed connection, and slidable connection in the front-back direction, wherein the pivot of the pivot connection is perpendicular to the inner guide rod.

[0189] Alternatively, when the support frame changes between a contracted working state and an expanded working state, the distance between the front and rear ends of the connecting strip can be variably set.

[0190] Alternatively, the connecting strip is a rigid elastic sheet that is radially elastic, and the connecting strip is bent when the support frame is in a contracted working state.

[0191] Alternatively, the connecting bar includes multiple sections, with the ends of two adjacent sections pivotally connected to form a chain, the inner guide rod and / or the outer guide rod pivotally connected to an adjacent section, and the outer end rod pivotally connected to an adjacent section, wherein the centerline of each pivot is spatially perpendicular to the inner guide rod.

[0192] Alternatively, the connecting bar includes multiple sections of rod, which are slidably connected to form a telescopic rod. The outer end rod is pivotally connected to the end of an adjacent section of rod, and the outer guide rod and / or inner guide rod are pivotally connected to an adjacent section of rod. The centerline of each pivot is spatially perpendicular to the inner guide rod.

[0193] Optionally, the connecting strip includes a connecting strip located at the front of the outer end rod and a connecting strip located at the rear of the outer end rod; the rear end of the connecting strip located at the front of the outer end rod is connected to the front end of the outer end rod, and the front end of the connecting strip located at the front of the outer end rod is connected to the inner guide rod; the front end of the connecting strip located at the rear of the outer end rod is connected to the rear end of the outer end rod, and the rear end of the connecting strip located at the rear of the outer end rod is connected to the outer guide tube.

[0194] Alternatively, the inner guide rod and the middle guide tube are positioned relatively fixedly in the front-back direction, and the outer guide tube and the middle guide tube are positioned relatively fixedly in the front-back direction.

[0195] Alternatively, the support frame includes an inner support frame and multiple outer support rods connected to the inner support frame. The outer support rods are parallel to the middle guide tube, and the multiple outer support rods are distributed in a cylindrical shape around the inner support frame. The inner end of the electrode film is connected to one of the outer support rods.

[0196] Alternatively, the length of the electrode film in the front-back direction is greater than or equal to the length of the outer support rod in the front-back direction, and the length difference between the two is less than 30 mm, preferably less than 2 mm.

[0197] Alternatively, when the support frame is in a contracted working state, the electrode film is wound around the support frame in multiple turns; when the support frame is in an expanded working state, the number of turns of the electrode film is greater than 1 turn and less than 2 turns.

[0198] Alternatively, when the distance between the front end of the support frame and the rear end of the support frame changes, the support frame can switch between a contracted working state and an expanded working state.

[0199] Alternatively, the electrode film is clamped to the support frame, so that the innermost ring of the electrode film is always in close contact with the support frame, and the electrode films of each adjacent ring are always in close contact with each other.

[0200] Optionally, the support frame includes an inner support frame and multiple outer support rods. The inner support frame includes multiple inner support rods. The front end of each inner support rod is fixed or pivotally connected to a front connecting ring to form the front end of the support frame. The rear end of each inner support rod is fixed or pivotally connected to a rear connecting ring to form the rear end of the support frame. The middle section of each inner support rod is fixedly connected to an outer support rod. Each outer support rod is parallel to the central guide tube, and the multiple outer support rods are distributed in a cylindrical shape around the inner support rod. The outer support rod has a front extension section extending forward of the middle section of the inner support rod, or / and the outer support rod has a rear extension section extending backward of the middle section of the inner support rod, such that the length of the outer support rod in the front-rear direction is greater than the length of the middle section of the inner support rod in the front-rear direction. When the support frame is in an expanded working state, the inner support rod is in an inward-facing arc shape. When the support frame is in a contracted working state, the inner support rod is approximately straight.

[0201] Alternatively, when the support frame is in an expanded working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0202] Optionally, the support frame includes an inner support frame, a middle support frame, and multiple outer support rods parallel to the middle guide tube. The front end of the inner support frame is fixed or pivotally connected to a front connecting ring to form the front end of the support frame, and the rear end of the inner support frame is fixed or pivotally connected to a rear connecting ring to form the rear end of the support frame. The inner support frame includes multiple inner support rods, and the middle support frame includes multiple middle support rods. When the support frame is in an expanded working state, the inner support rods are in an inward-facing arc shape, and the middle support rods are in an outward-facing arc shape. The middle support rods... The segments are respectively fixedly connected to the middle sections of each inner support rod. When the support frame is in the retracted working state, the middle support rod and the inner support rod are generally straight. The front end and the rear end of the middle support rod are respectively connected to the outer support rod. At least one of the two ends of the middle support rod, the front end and the rear end, is slidably connected to the outer support rod in the front-back direction. The multiple outer support rods are distributed in a cylindrical shape around the middle support rod. The length of the outer support rod in the front-back direction is greater than or equal to the length of the middle support rod in the front-back direction.

[0203] Alternatively, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the middle support rod in the front-rear direction, and the front end of the middle support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the middle support rod is located in front of or aligned with the rear end of the outer support rod; the length of the outer support rod in the front-rear direction is also greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0204] Another technical solution is a device for ablation therapy of the digestive tract, the device comprising: Slender central duct; A slender outer conduit is sleeved on the middle conduit, and the middle conduit is rotatably disposed relative to the outer conduit; An expandable component surrounds the central conduit. The expandable component includes a supporting frame and a flexible electrode membrane. The expandable component has a radially decreasing contraction working state and a radially increasing expansion working state. The supporting frame is connected to the central conduit. The deformable component of the supporting frame when changing between the contraction and expansion working states is made of a rigid elastic material. The rigid elastic material gives the supporting frame a radially outward elastic force when changing from the contraction to the expansion working state. The electrode membrane has multiple electrodes for receiving electrical signals. The electrode membrane is spirally wound around the supporting frame. The inner end of the electrode membrane is connected to the supporting frame, and the outer end of the electrode membrane is connected to the outer conduit via a connector.

[0205] Alternatively, the device further includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected middle guide tube to rotate in the forward direction relative to the outer guide tube, so that while the electrode membrane expands radially, the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected middle guide tube to rotate in the reverse direction relative to the outer guide tube, so that while the electrode membrane contracts radially, the electrode membrane also compresses the supporting frame to contract radially.

[0206] Alternatively, the device further includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected outer conduit to rotate in the opposite direction relative to the middle conduit, causing the electrode membrane to expand radially while the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected outer conduit to rotate in the forward direction relative to the middle conduit, causing the electrode membrane to contract radially while the electrode membrane compresses the supporting frame to also contract radially.

[0207] Optionally, the support frame includes multiple inner support rods and multiple outer support rods parallel to the central guide tube and connected to the ends of the inner support rods. The multiple outer support rods are distributed in a cylindrical shape around the central guide tube. The inner middle section of each inner support rod is fixedly connected to the central guide tube. At least one of the two ends of the inner support rod, the front end and the rear end, is slidably connected to a corresponding outer support rod in the front-rear direction. When the support frame is in the expanded working state, the inner support rod is in an arc shape with its opening facing outward. When the support frame is in the contracted working state, the inner support rod is in a roughly straight shape.

[0208] Alternatively, the outer support rod has a front extension section extending forward toward the front end of the inner support rod, or / and the outer support rod has a rear extension section extending backward toward the rear end of the inner support rod, such that when the support frame is in a retracted working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0209] Alternatively, the support frame includes multiple annular rods and multiple outer support rods parallel to the central guide tube. The inner side of each annular rod is fixedly connected to the central guide tube, and the outer side of each annular rod is fixedly connected to a corresponding outer support rod. When the support frame is in the expansion working state, the annular rods are open annular shapes, and when the support frame is in the contraction working state, the annular rods are flattened into approximately straight lines.

[0210] Alternatively, the outer support rod has a front extension section extending forward toward the outer side of the annular rod, or / and the outer support rod has a rear extension section extending backward toward the outer side of the annular rod, such that when the support frame is in the retracted working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the annular rod in the front-rear direction, and the front end of the annular rod is located behind or aligned with the front end of the outer support rod, and the rear end of the annular rod is located in front of or aligned with the rear end of the outer support rod.

[0211] Optionally, the support frame includes multiple inner support rods and multiple outer support rods parallel to the central guide tube. The multiple outer support rods are distributed in a cylindrical shape around the central guide tube. The inner middle section of each inner support rod is fixedly connected to the central guide tube, and the two outer ends of each inner support rod are fixedly connected to a corresponding outer support rod. When the support frame is in the expanded working state, the front part of the inner support rod is an arc shape with the opening facing backward, and the rear part of the inner support rod is an arc shape with the opening facing forward. The inner support rods and the outer support rods form a closed ring. When the support frame is in the contracted working state, the ring is flattened.

[0212] Alternatively, the outer support rod has a front extension section extending forward toward the front end of the inner support rod, or / and the outer support rod has a rear extension section extending backward toward the rear end of the inner support rod, such that when the support frame is in a retracted working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0213] Alternatively, the support frame has a front end and a rear end, one end of the support frame is sleeved on the central guide tube, and this end is a movable end that is allowed to slide in the front-back direction and rotate in the circumferential direction relative to the central guide tube, and the other end of the support frame is connected to the central guide tube.

[0214] Alternatively, one end of the support frame may be suspended, while the other end of the support frame may be connected to the central conduit.

[0215] Alternatively, the support frame has a front end and a rear end, one end of the support frame is sleeved on the central guide tube, and the end is slidable in the front-back direction and is prohibited from relative rotation with the central guide tube, and the other end of the support frame is connected to the central guide tube.

[0216] Alternatively, the support frame has a front end and a rear end, one end of the support frame is sleeved on the central guide tube, and the end is rotatably connected to the central guide tube in a circumferential direction but not in a sliding direction, and the other end of the support frame is connected to the central guide tube.

[0217] Alternatively, the support frame has a front end and a rear end, one end of which is fixedly disposed with the central guide tube, and the other end of the support frame is connected to the central guide tube.

[0218] Alternatively, the support frame has a front end and a rear end, one end is pivotally connected to a connecting ring, the pivot is perpendicular to the central guide tube, the connecting ring is sleeved on the central guide tube, the connecting ring is a movable end that allows sliding in the front-back direction and rotation in the circumferential direction relative to the central guide tube, and the other end of the support frame is connected to the central guide tube.

[0219] Alternatively, the support frame has a front end and a rear end, one end is pivotally connected to a connecting ring, the pivot being perpendicular to the central guide tube, the connecting ring being sleeved on the central guide tube, the connecting ring being configured to allow sliding relative to the central guide tube in the front-back direction but prohibiting rotation in the circumferential direction, and the other end of the support frame being connected to the central guide tube.

[0220] Alternatively, the support frame has a front end and a rear end, one end is pivotally connected to a connecting ring, the pivot being perpendicular to the central guide tube, the connecting ring being sleeved on the central guide tube, the connecting ring being configured to allow rotation in the circumferential direction relative to the central guide tube and to prevent sliding in the front-to-back direction, and the other end of the support frame being connected to the central guide tube.

[0221] Alternatively, the support frame has a front end and a rear end, one end is pivotally connected to the central guide tube, the pivot being perpendicular to the central guide tube, and the other end of the support frame is connected to the central guide tube.

[0222] Alternatively, the other end of the support frame may be fixedly connected to the central conduit.

[0223] Alternatively, the other end of the support frame may be connected to the central guide tube in a manner that allows sliding in the front-to-back direction but prohibits relative rotation.

[0224] Alternatively, the other end of the support frame may be a movable end that is slidable in the front-to-back direction and rotatable in the circumferential direction relative to the central guide tube.

[0225] Alternatively, the other end of the support frame may be configured to be rotatable in the circumferential direction but not slidable in the front-to-back direction relative to the central guide tube.

[0226] Alternatively, another connecting ring is pivotally connected to the other end of the support frame, the pivot being perpendicular to the central guide tube, and the other connecting ring is sleeved on the central guide tube and fixedly connected to it.

[0227] Alternatively, another connecting ring is pivotally connected to the other end of the support frame, the pivot being perpendicular to the central guide tube, and the other connecting ring is sleeved on the central guide tube and is configured to be rotatable in the circumferential direction but not slidable in the front-back direction relative to the central guide tube.

[0228] Alternatively, another connecting ring is pivotally connected to the other end of the support frame, the pivot being perpendicular to the central guide tube, and the other connecting ring is sleeved on the central guide tube and is connected relative to the central guide tube in a front-back direction but is prohibited from relative rotation.

[0229] Alternatively, another connecting ring is pivotally connected to the other end of the support frame, the pivot being perpendicular to the central guide tube, and the other connecting ring is sleeved on the central guide tube and is configured to slide in the front-back direction and rotate in the circumferential direction relative to the central guide tube.

[0230] Alternatively, the connector includes an outer end rod and a connecting strip that is rigid in the circumferential direction. The outer end rod is parallel to the middle guide tube and connected to the outer end of the electrode membrane. The front end of the connecting strip is connected to the rear end of the outer end rod, and the rear end of the connecting strip is connected to the outer guide tube. During the process of the support frame changing from a contracted working state to an expanded working state, the outer end rod gradually moves away from the middle guide tube. During the process of the support frame changing from an expanded working state to a contracted working state, the outer end rod gradually moves closer to the middle guide tube.

[0231] Alternatively, the front end of the connecting strip and the rear end of the outer end rod are selected from the following three connection structures: pivot connection, fixed connection, and slidable connection in the front-back direction, wherein the pivot of the pivot connection is perpendicular to the middle guide tube; the rear end of the connecting strip and the outer guide tube are selected from the following three connection structures: pivot connection, fixed connection, and slidable connection in the front-back direction, wherein the pivot of the pivot connection is perpendicular to the middle guide tube.

[0232] Alternatively, when the support frame changes between a contracted working state and an expanded working state, the distance between the front and rear ends of the connecting strip can be variably set.

[0233] Alternatively, the connecting strip is a rigid elastic sheet that is radially elastic, and the connecting strip is bent when the support frame is in a contracted working state.

[0234] Alternatively, the connecting bar includes multiple sections, with the ends of two adjacent sections pivotally connected to form a chain, the outer conduit pivotally connected to the rear end of an adjacent section, and the rear end of the outer end rod pivotally connected to the front end of an adjacent section, with each pivot perpendicular to the middle conduit.

[0235] Alternatively, the connecting bar includes multiple sections of rod, which are slidably connected to form a telescopic rod. The rear end of the outer rod is pivotally connected to the front end of an adjacent section of rod, and the outer guide tube is pivotally connected to the rear end of an adjacent section of rod. The centerline of each pivot is perpendicular to the middle guide tube.

[0236] Alternatively, the device may further include an inner guide rod, on which the middle guide tube is sleeved, and the middle guide tube is rotatably disposed relative to the inner guide rod.

[0237] Alternatively, the inner guide rod is fixedly disposed with the outer guide tube, and a front guide cap is fixedly connected to the front end of the inner guide rod. The inner guide rod is a tubular body with a guide wire cavity, and the center of the front guide cap also has a guide wire cavity and communicates with the guide wire cavity of the inner guide rod.

[0238] Optionally, the connector includes an outer end rod and a connecting strip that is rigid in the circumferential direction. The outer end rod is parallel to the inner guide rod and connected to the outer end of the electrode membrane. One end of the connecting strip is connected to the outer end rod, and the other end of the connecting strip is connected to the outer guide tube and / or the inner guide rod. During the transition of the support frame from a contracted working state to an expanded working state, the outer end rod gradually moves away from the inner guide rod. During the transition of the support frame from an expanded working state to a contracted working state, the outer end rod gradually moves closer to the inner guide rod.

[0239] Alternatively, the connecting strip and the outer end rod are selected from the following three connection structures: pivot connection, fixed connection, and slidable connection in the front-back direction, wherein the pivot of the pivot connection is perpendicular to the inner guide rod; the connecting strip and the outer guide tube and / or inner guide rod are selected from the following three connection structures: pivot connection, fixed connection, and slidable connection in the front-back direction, wherein the pivot of the pivot connection is perpendicular to the inner guide rod.

[0240] Alternatively, when the support frame changes between a contracted working state and an expanded working state, the distance between the front and rear ends of the connecting strip can be variably set.

[0241] Alternatively, the connecting strip is a rigid elastic sheet that is radially elastic, and the connecting strip is bent when the support frame is in a contracted working state.

[0242] Alternatively, the connecting bar includes multiple sections, with the ends of two adjacent sections pivotally connected to form a chain, the inner guide rod and / or the outer guide rod pivotally connected to an adjacent section, and the outer end rod pivotally connected to an adjacent section, wherein the centerline of each pivot is spatially perpendicular to the inner guide rod.

[0243] Alternatively, the connecting bar includes multiple sections of rod, which are slidably connected to form a telescopic rod. The outer end rod is pivotally connected to the end of an adjacent section of rod, and the outer guide rod and / or inner guide rod are pivotally connected to an adjacent section of rod. The centerline of each pivot is spatially perpendicular to the inner guide rod.

[0244] Optionally, the connecting strip includes a connecting strip located at the front of the outer end rod and a connecting strip located at the rear of the outer end rod; the rear end of the connecting strip located at the front of the outer end rod is connected to the front end of the outer end rod, and the front end of the connecting strip located at the front of the outer end rod is connected to the inner guide rod; the front end of the connecting strip located at the rear of the outer end rod is connected to the rear end of the outer end rod, and the rear end of the connecting strip located at the rear of the outer end rod is connected to the outer guide tube.

[0245] Alternatively, the inner guide rod and the middle guide tube are positioned relatively fixedly in the front-back direction, and the outer guide tube and the middle guide tube are positioned relatively fixedly in the front-back direction.

[0246] Alternatively, the support frame includes an inner support frame and multiple outer support rods connected to the inner support frame. The outer support rods are parallel to the middle guide tube, and the multiple outer support rods are distributed in a cylindrical shape around the inner support frame. The inner end of the electrode film is connected to one of the outer support rods.

[0247] Alternatively, the length of the electrode film in the front-back direction is greater than or equal to the length of the outer support rod in the front-back direction, and the length difference between the two is less than 30 mm, preferably less than 2 mm.

[0248] Alternatively, when the support frame is in a contracted working state, the electrode film is wound around the support frame in multiple turns; when the support frame is in an expanded working state, the number of turns of the electrode film is greater than 1 turn and less than 2 turns.

[0249] Alternatively, when the distance between the front end of the support frame and the rear end of the support frame changes, the support frame can switch between a contracted working state and an expanded working state.

[0250] Alternatively, the electrode film is clamped to the support frame, so that the innermost ring of the electrode film is always in close contact with the support frame, and the electrode films of each adjacent ring are always in close contact with each other.

[0251] Optionally, the support frame includes an inner support frame and multiple outer support rods. The inner support frame includes multiple inner support rods. The front end of each inner support rod is fixed or pivotally connected to a front connecting ring to form the front end of the support frame. The rear end of each inner support rod is fixed or pivotally connected to a rear connecting ring to form the rear end of the support frame. The middle section of each inner support rod is fixedly connected to an outer support rod. Each outer support rod is parallel to the central guide tube, and the multiple outer support rods are distributed in a cylindrical shape around the inner support rod. The outer support rod has a front extension section extending forward of the middle section of the inner support rod, or / and the outer support rod has a rear extension section extending backward of the middle section of the inner support rod, such that the length of the outer support rod in the front-rear direction is greater than the length of the middle section of the inner support rod in the front-rear direction. When the support frame is in an expanded working state, the inner support rod is in an inward-facing arc shape. When the support frame is in a contracted working state, the inner support rod is approximately straight.

[0252] Alternatively, when the support frame is in an expanded working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0253] Optionally, the support frame includes an inner support frame, a middle support frame, and multiple outer support rods parallel to the middle guide tube. The front end of the inner support frame is fixed or pivotally connected to a front connecting ring to form the front end of the support frame, and the rear end of the inner support frame is fixed or pivotally connected to a rear connecting ring to form the rear end of the support frame. The inner support frame includes multiple inner support rods, and the middle support frame includes multiple middle support rods. When the support frame is in an expanded working state, the inner support rods are in an inward-facing arc shape, and the middle support rods are in an outward-facing arc shape. The middle support rods... The segments are respectively fixedly connected to the middle sections of each inner support rod. When the support frame is in the retracted working state, the middle support rod and the inner support rod are generally straight. The front end and the rear end of the middle support rod are respectively connected to the outer support rod. At least one of the two ends of the middle support rod, the front end and the rear end, is slidably connected to the outer support rod in the front-back direction. The multiple outer support rods are distributed in a cylindrical shape around the middle support rod. The length of the outer support rod in the front-back direction is greater than or equal to the length of the middle support rod in the front-back direction.

[0254] Alternatively, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the middle support rod in the front-rear direction, and the front end of the middle support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the middle support rod is located in front of or aligned with the rear end of the outer support rod; the length of the outer support rod in the front-rear direction is also greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

[0255] This disclosure provides another expandable component for gastrointestinal ablation therapy, the expandable component having a contracted working state and an expanded working state, the expandable component including a support and an electrode membrane provided with electrodes; the support includes: The front and rear connectors are spaced apart; and Multiple support units are spaced apart along the perimeter of the front connector or the rear connector; At least one of the plurality of support units includes an outer support rod, a first connecting rod, and a second connecting rod. The front end of the first connecting rod is connected to the front connector, the rear end of the first connecting rod is connected to the rear end of the outer support rod, the front end of the second connecting rod is connected to the front end of the outer support rod, and the rear end of the second connecting rod is connected to the rear connector. The electrode membrane is wound around the plurality of support units, and the inner end of the electrode membrane is connected to the bracket; the first link and / or the second link have elastic segments, and when the expandable component is in the contracted working state, the elastic segments tend to move the outer support rod outward along the diameter direction of the front connector or the rear connector, so as to drive the electrode membrane to expand along the diameter direction and switch to the expanded working state.

[0256] In this design, the supporting skeleton, when contracted and equipped with electrode membranes of equal length in the anterior and posterior directions, is shorter in length in the anterior and posterior directions, making it easier to pass through the curved digestive tract without damaging the lining of the digestive tract.

[0257] In a preferred embodiment, the elastic segment includes at least one of the front and rear ends of the first link and the front and rear ends of the second link.

[0258] In a more preferred embodiment, the front end of the first link and the front connector are integral, and the front end of the first link is elastic and has a tendency to move outward relative to the front connector; And / or, the rear end of the first link and the rear end of the outer support rod are integral, and the rear end of the first link is elastic and has a tendency to push the outer support rod outward; And / or, the rear end of the second link and the rear connector are integral, and the rear end of the second link is elastic and has a tendency to move outward relative to the rear connector; And / or, the front end of the second link and the front end of the outer support rod are integral, and the front end of the second link is elastic and has a tendency to push the outer support rod outward.

[0259] In a further preferred embodiment, when the bracket is in a released state without any external force applied, the first link bends outward and tilts relative to the front connector, the second link bends outward and tilts relative to the rear connector, and the outer support rod is located outside the front connector and the rear connector.

[0260] In a preferred embodiment, the support is made by cutting and shaping a flexible tube; when the expandable component is in the contracted working state, the support is assembled into a tubular shape.

[0261] In a more preferred embodiment, the pipe is a metal pipe, preferably a stainless steel pipe, a nickel alloy pipe, a titanium alloy pipe, or a nickel-titanium alloy pipe; and / or, the pipe is a pipe of equal diameter.

[0262] In a more preferred embodiment, the front connector is formed from the front end of the tube, the rear connector is formed from the rear end of the tube, and the first link, the second link, and the outer support rod are formed by cutting the tube body located between its front and rear ends along its length.

[0263] In a further preferred embodiment, the first connecting rod and the second connecting rod are located on opposite sides of the outer support rod, and the front connector, the first connecting rod, the outer support rod, the second connecting rod and the rear connector are connected in sequence and are integral.

[0264] In a further preferred embodiment, the first link is heat-shaped to have a tendency to bend outward relative to the front connector, and the second link is heat-shaped to have a tendency to bend outward relative to the rear connector.

[0265] In a preferred embodiment, the front connector is annular and the rear connector is annular.

[0266] In a preferred embodiment, the width of the front end and / or rear end of the first connecting rod is smaller than the width of its middle portion, the width of the front end and / or rear end of the second connecting rod is smaller than the width of its middle portion, and the width of the front end and / or rear end of the outer support rod is greater than the width of its middle portion.

[0267] In a preferred embodiment, the front and / or rear ends of the outer support rod are provided with connecting holes, the front connector is provided with connecting holes, and the rear connector is provided with connecting holes.

[0268] In a preferred embodiment, the outer end of the electrode membrane is connected to a connector to connect an inner guide rod or outer catheter of a device for gastrointestinal ablation therapy, thereby causing the electrode membrane to contract.

[0269] A second aspect of this disclosure provides a method for manufacturing the expandable component, comprising the preparation of a scaffold, the scaffold being prepared by the following steps: S11. Provide a pipe; S12. Cut the pipe along its length to form multiple cutting lines. The multiple cutting lines are spaced apart along the circumference of the pipe to form a first connecting rod, an outer support rod, and a second connecting rod. The starting point of each cutting line is a distance from the front edge of the pipe so that the front end of the pipe forms a front connector. The ending point of each cutting line is a distance from the rear edge of the pipe so that the rear end of the pipe forms a rear connector. S13. Cut along the circumference of the pipe to separate the rear end of the first connecting rod and the rear end of the outer support rod from the rear connector, and to separate the front end of the second connecting rod and the front end of the outer support rod from the front connector. S14. Shaping: tilting the first connecting rod outward relative to the front connecting member and tilting the second connecting rod outward relative to the rear connecting member to obtain the bracket.

[0270] In a preferred embodiment, in step S14, the cut pipe is heated and shaped.

[0271] A third aspect of this disclosure provides an apparatus for gastrointestinal ablation therapy, comprising: Middle catheter; The expandable component used for ablation therapy of the digestive tract; The front or rear connector of the expandable component is connected to the central conduit.

[0272] In a preferred embodiment, both the front connector and the rear connector are connected to the central conduit, and at least one of them is movably sleeved on the central conduit to be able to rotate relative to the central conduit and move in the front-back direction.

[0273] In a preferred embodiment, the device includes an inner guide rod, a middle guide tube sleeved on the inner guide rod and rotatable relative to the inner guide rod, a front connector movably connected to the inner guide rod, and a rear connector connected to the middle guide tube.

[0274] In a preferred embodiment, the device includes an outer conduit sleeved on the middle conduit and rotatable relative to the middle conduit, and the outer end of the electrode membrane is connected to the outer conduit via a connector.

[0275] In a more preferred embodiment, the connector includes an outer end rod and a connecting strip that is rigid in the circumferential direction. The outer end rod is parallel to the middle guide tube and connected to the outer end of the electrode membrane. The front end of the connecting strip is connected to the rear end of the outer end rod, and the rear end of the connecting strip is connected to the outer guide tube. During the process of the expandable component changing from a contracted working state to an expanded working state, the outer end rod gradually moves away from the middle guide tube. During the process of the support frame changing from an expanded working state to a contracted working state, the outer end rod gradually moves closer to the middle guide tube.

[0276] The expandable component of this design improves the fit between the electrode and the intestinal lining. Furthermore, the front connector, the first connecting rod, the outer support rod, the second connecting rod, and the rear connector are sequentially connected, allowing for a single, integrated design. This simplifies the manufacturing process and reduces costs. Moreover, the cross-shaped structure formed by the first and second connecting rods significantly shortens the length of the stent in its contracted state compared to existing stents, facilitating its transport within the digestive tract and reducing the risk of the expandable component scratching the digestive tract during transport.

[0277] In a preferred embodiment, the outer support rod is parallel to the central conduit.

[0278] This disclosure has the following advantages compared to the prior art: By utilizing the relative rotation between one component and another, the number of turns of the electrode membrane changes, which in turn causes a change in the radial direction of the supporting frame. This disclosed solution achieves controllable operation of the electrode membrane's expansion and contraction process. The supporting frame effectively supports the electrode membrane, ensuring that it receives radial outward support during expansion and in its operating state, resulting in good fit between the electrode membrane and the inner wall of the digestive tract. Attached Figure Description

[0279] Figure 1 This is a system diagram of the present disclosure, and its supporting framework is a first embodiment; Figure 2 for Figure 1 The ablation component is shown in a cross-sectional magnified view along the AA direction, with the expandable component in a contracted working state. Figure 3 This is a partial view of the ablation component, whose supporting frame is the first embodiment, and the expandable component is in the expansion working state; Figure 4 for Figure 3 A BB-direction sectional view, showing the expandable component in the expansion working state; Figure 5 This is a three-dimensional view of the ablation component from one angle, with its supporting frame being the first embodiment, and the expandable component in an expanding working state. Figure 6 This is a three-dimensional view of the ablation component from another angle, with its supporting frame being the first embodiment, and the expandable component in an expanding working state. Figure 7 The following is a partial view of the ablation component from another angle after omitting the electrode film. Its support frame is the first embodiment, and the expandable component is in a contracted working state. Figure 8The following is a partial view of the ablation component from another angle after omitting the electrode film. Its support frame is the first embodiment, and the expandable component is in the expansion working state. Figure 9 for Figure 1 Enlarged cross-sectional view of the operating handle in the CC direction; Figure 10 This is an external view of the ablation component at an angle, with its supporting frame being the first embodiment, and the expandable component in an expanding working state; Figure 11 for Figure 10 The enlarged cross-sectional view along the DD direction shows the expandable component in its expansion working state. Figure 12 for Figure 1 The enlarged cross-sectional view along the EE direction shows the expandable component in a contracted working state. To show the electrode films of each ring, gaps are left between each ring of electrode films. In reality, the electrode films of each ring are tightly attached to each other, and the innermost electrode film is also tightly attached to the outer support rod. Figure 13 This is a partial view of the ablation component from another angle, showing its supporting frame as a second embodiment, with the expandable component in an expanded working state. Figure 14 for Figure 13 A cross-sectional view in the FF direction; Figure 15 This is a partial view of the ablation component from another angle, showing its support frame in a second embodiment, with the expandable component in a contracted working state. Figure 16 for Figure 15 A cross-sectional view along the GG direction, showing the expandable component in a retracted working state; Figure 17 for Figure 14 The enlarged cross-sectional view in the HH direction shows that gaps are left between the electrode films in order to show the electrode films in each ring. In reality, the electrode films in each ring are close to each other, and the innermost electrode film is also close to the outer support rod. Figure 18 for Figure 16 Enlarged sectional view in direction II; Figure 19 This is a perspective view of the ablation component at one angle. Its supporting frame is a second embodiment, and the expandable component is in an expansion working state. Figure 20 This is a perspective view of the ablation component from another angle. Its supporting frame is a second embodiment, and the expandable component is in an expansion working state. Figure 21 for Figure 9 A magnified cross-sectional view in the JJ direction; Figure 22-1 This is an axial structural cross-sectional view of an embodiment of the ablation component. The support frame is in an expanded working state. The connector connects the outer end of the outer conduit and the outer end of the electrode membrane. The front end of the support frame is the front end of the inner support rod. The front end of the inner support rod is pivotally connected to the front connecting ring. The rear end of the support frame is the rear end of the inner support rod. The rear end of the inner support rod is pivotally connected to the rear connecting ring. Each pivot is spatially perpendicular to the inner guide rod. Figure 22-2 for Figure 22-1 Enlarged view of point L; Figure 22-3 for Figure 22-1 Enlarged view at point M; Figure 22-4 This is an axial structural cross-sectional view of one embodiment of the ablation component. The support frame is in an expanded working state, and the connector connects the inner guide rod and the outer end of the electrode film. The support frame is the first embodiment. Figure 23 for Figure 22-4 A cross-sectional view of the ablation component in the contracted working state; Figure 24 The axial structural cross-sectional view of one embodiment of the ablation component shows the support frame in an expanded working state. The actuator drives the outer and middle conduits to rotate relative to each other simultaneously, causing the inner end and outer end of the electrode film to rotate relative to each other simultaneously. The support frame is a second embodiment. Figure 25 This is an axial cross-sectional view of the operating handle of the actuator, which drives the outer and middle guide tubes to rotate relative to each other simultaneously. Figure 26 for Figure 25 Enlarged cross-sectional view in the KK direction; Figure 27 This is an axial structural cross-sectional view of an embodiment of the ablation component. The expandable component is in an expansion working state. The front connecting ring is rotatably and positioned in the front-back direction on the inner guide rod, and the rear connecting ring is slidably but not rotatably fitted on the middle guide tube in the front-back direction. Figure 28 for Figure 27 Axial structural cross-sectional view of the expandable component in its retracted working state; Figure 29-1 This is an axial structural cross-sectional view of an embodiment of the ablation component. The expandable component is in an expansion working state. The connector is connected to the outer end of the electrode film. The connector is also connected to the inner guide rod and the outer conduit. The connecting bar is a chain. Figure 29-2 This is an axial structural cross-sectional view of an embodiment of the ablation component, in which the expandable component is in an expanding working state, and the connecting strip is a rigid elastic sheet; Figure 29-3This is an axial structural cross-sectional view of an embodiment of the ablation component, showing the expandable component in an expanded working state, with the connecting bar being a telescopic rod. Figure 30 This is an axial structural cross-sectional view of an embodiment of the ablation component without an inner guide rod, with the expandable component in a contracted working state. Figure 31 for Figure 30 Axial structural cross-sectional view of the expandable component in its expanded working state; Figure 32 This is an axial structural cross-sectional view of an embodiment of the ablation component without an inner guide rod. The expandable component is in a contracted working state, and both the front and rear connecting rings are connected to the middle guide tube in a sliding but non-rotating direction. Figure 33 for Figure 32 Axial structural cross-sectional view of the expandable component in its expanded working state; Figure 34 The ablation component has no inner guide rod. The axial cross-sectional view of the actuator's operating handle shows the actuator driving the inner catheter to rotate relative to the outer catheter. Figure 35-1 This is an axial structural cross-sectional view of one embodiment of the ablation component. The expandable component is in an expansion working state, and the inner middle section of the inner support skeleton is fixedly connected to the central guide tube. The support skeleton is a third embodiment. Figure 35-2 This is an axial structural cross-sectional view of one embodiment of the ablation component. The expandable component is in a contracted working state, and the inner middle section of the inner support skeleton is fixedly connected to the central guide tube. The support skeleton is a third embodiment. Figure 36-1 This is an axial structural cross-sectional view of one embodiment of the ablation component. The expandable component is in an expansion working state, and the inner middle section of the inner support skeleton is fixedly connected to the central guide tube. The support skeleton is the fourth embodiment. Figure 36-2 This is an axial structural cross-sectional view of one embodiment of the ablation component. The expandable component is in a contracted working state, and the inner middle section of the inner support skeleton is fixedly connected to the central guide tube. The support skeleton is the fourth embodiment. Figure 37-1 This is a schematic diagram of a device for ablation therapy of the digestive tract according to an embodiment of the present disclosure, wherein the expandable component is in an expanded working state and the supporting frame is the fifth embodiment.

[0280] Figure 37-2 for Figure 37-1 A cross-sectional view along the NN direction, showing the supporting skeleton in the fifth embodiment.

[0281] Figure 37-3This is a schematic diagram of another perspective of a device for gastrointestinal ablation therapy according to an embodiment of the present disclosure, wherein the expandable component is in an expanded working state and the supporting frame is the fifth embodiment.

[0282] Figure 37-4 for Figure 37-3 A cross-sectional view along the OO direction, showing the supporting frame in the fifth embodiment.

[0283] Figure 37-5 for Figure 37-4 A partially enlarged schematic diagram at point P, showing the supporting frame in the fifth embodiment.

[0284] Figure 37-6 This is a partial structural schematic diagram of a device for gastrointestinal ablation therapy according to an embodiment of the present disclosure, with the support frame being the fifth embodiment.

[0285] Figure 37-7 for Figure 37-6 A cross-sectional view along the QQ direction, showing the supporting frame in the fifth embodiment.

[0286] Figure 37-8 This is a partial structural schematic diagram of a device for gastrointestinal ablation therapy according to an embodiment of the present disclosure, wherein the expandable component is in a contracted working state and the supporting frame is the fifth embodiment.

[0287] Figure 37-9 for Figure 37-8 A cross-sectional view along the RR direction, showing the supporting frame in the fifth embodiment.

[0288] Figure 37-10 This is a partial structural schematic diagram from another perspective of an apparatus for gastrointestinal ablation therapy according to an embodiment of the present disclosure, wherein the expandable component is in a contracted working state and the supporting frame is the fifth embodiment.

[0289] Figure 37-11 for Figure 37-10 A cross-sectional view along the SS direction, showing the supporting frame in the fifth embodiment.

[0290] Figure 37-12 and Figure 37-13 This is a three-dimensional schematic diagram of the support frame according to an embodiment of the present disclosure from two perspectives after expansion. The support frame is the fifth embodiment.

[0291] Figure 37-14 This is a side view of the support frame after expansion according to an embodiment of the present disclosure. The support frame is the fifth embodiment.

[0292] Figure 37-15 This is a three-dimensional schematic diagram of the support frame after shrinkage according to an embodiment of the present disclosure. The support frame is the fifth embodiment.

[0293] Figure 37-16 This is a side view of the support frame after shrinkage according to an embodiment of the present disclosure. The support frame is the fifth embodiment.

[0294] Figure 37-17 This is a cross-sectional schematic diagram of another device for gastrointestinal ablation therapy according to an embodiment of the present disclosure, wherein no inner guide rod is provided, and the support frame is the fifth embodiment.

[0295] Figure 37-18 for Figure 37-1 A magnified view of a device used for ablation therapy of the digestive tract.

[0296] Figure 37-19 for Figure 37-2 A magnified view of a device used for ablation therapy of the digestive tract.

[0297] Figure 37-20 for Figure 37-3 A magnified view of a device used for ablation therapy of the digestive tract.

[0298] Figure 37-21 for Figure 37-4 A magnified view of a device used for ablation therapy of the digestive tract.

[0299] Figure 37-22 for Figure 37-17 A magnified view of a device used for ablation therapy of the digestive tract.

[0300] in, 1. Inner guide rod; 2. Middle guide tube; 3. Outer guide tube; 4. Expandable component; 5. Support frame; 6. Electrode membrane; 7. Electrode; 8. Inner end of electrode membrane; 9. Outer end of electrode membrane; 10. Internal gear; 11. Intermediate gear; 12. Front connecting ring; 13. Rear connecting ring; 14. Outer end rod; 15. Connecting bar; 16. Internal gear ring; 17. Section rod; 18. Pivot; 19. Inner support frame; 20. Outer support rod; 21. Front extension section; 22. Rear extension section; 23. Middle support frame; 24. Inner support rod; 25. Middle support rod; 26. Front end of middle support rod; 27. Rear end of middle support rod; 28. Operating handle; 29. ​​Front guide cap; 30. Guide wire 31. Cavity; 32. Signal generator; 33. Rear guide cap; 34. Sliding groove; 35. Knob; 36. Operating handle body; 37. Rivet; 38. First guide groove; 39. Second guide groove; 40. First bevel gear; 41. Second bevel gear; 42. Third bevel gear; 43. Annular protrusion; 44. First limiting member; 45. Second limiting member; 46. First axial rib; 47. Second axial rib; 48. Front limiting block of the middle tube; 49. Rear limiting block of the middle tube; 50. Ring rod; 51. Support unit; 52. First connecting rod; 52a. Front end; 52b. Rear end; 53. Second connecting rod; 53a. Front end; 53b. Rear end; 54. Cutting line. Detailed Implementation

[0301] The embodiments will be further described below with reference to the accompanying drawings. The digestive tract in this disclosure refers to the oral cavity, esophagus, stomach, duodenum, small intestine, large intestine, anus, etc. The upper digestive tract refers to the areas into which the ablation component of this disclosure can extend, including the esophagus, stomach, and duodenum. This disclosure is particularly applicable to the upper digestive tract. In this disclosure, "anterior" refers to the direction in which the ablation component advances into the digestive tract, and "posterior" refers to the direction in which it retracts, for example... Figure 1In this disclosure, "front" refers to the direction facing left and "rear" refers to the direction facing right. "Front" and "rear" are also defined in this direction. "Axial" in this disclosure refers to the direction of the central axis of the central catheter. "Radial" in this disclosure refers to the radial direction of the central catheter, which is perpendicular to the axial direction of the central catheter; "circumferential" refers to the circumferential direction of the central catheter. In this disclosure, for concentrically connected and extending components (e.g., between the outer catheter, central catheter, and inner guide rod), their respective axial, radial, and circumferential directions are the same. "Inner" in this disclosure is relative to "outer." Therefore, "inner side" or "inner end" refers to the side or end radially closer to the inner guide rod (in embodiments without an inner guide rod, it is closer to the central catheter), and "outer side" or "outer end" refers to the side or end radially farther from the inner guide rod (in embodiments without an inner guide rod, it is farther from the central catheter). "Front end" also refers to the end farther from the operator (doctor), also known in the industry as the distal end, and "rear end" refers to the end closer to the operator, also known in the industry as the proximal end. In this disclosure, the term "part" (e.g., "front part," "rear part," "external," "internal") used with directional terms refers to the portion beyond the corresponding median line. For example, "front part" refers to the portion located in front of the median line in the front-back direction. Conversely, the term "end" or "end point" (e.g., "front end," "front end," "rear end," "outer end," "inner end") used with directional terms refers to the portion beyond the corresponding median line and furthest from it. For example, "front end" or "front end" refers to the portion in front of the median line in the front-back direction and furthest from it. Thus, the "end point" of a corresponding directional term is part of the "part" (e.g., "front end" is part of the "front part"). Correspondingly, "front-middle part" refers to the portion between the median line in the front-back direction and the "front end," and both "front-middle part" and "front end" belong to the "front part"; "rear-middle part" refers to the portion between the median line in the front-back direction and the "rear end," and both "rear-middle part" and "rear end" belong to the "rear part."

[0302] Unless otherwise specified, the meaning of "a component is perpendicular to or parallel to another component" in this disclosure refers to the direction of the axis of one component being perpendicular to or parallel to the direction of the axis of the other component. For example, "a pivot is perpendicular to the central guide tube" means that the direction of the axis of the pivot is perpendicular to the direction of the axis of the central guide tube. Similarly, "the electrode membrane connector is parallel to the central guide tube" means that the direction of the axis of the electrode membrane connector is parallel to the direction of the axis of the central guide tube. The terms "forward" and "reverse" in this disclosure are merely definitions intended to facilitate understanding of the relevant embodiments of this disclosure and can refer to counterclockwise or clockwise directions, or vice versa. Figure 20For example, from the perspective of the near end to the far end, "forward" means counterclockwise, which is also the direction in which the electrode film 6 is wound; "reverse" means clockwise. The descriptions of "forward" and "reverse" are intended to facilitate understanding of the solutions of the relevant embodiments of this disclosure. Those skilled in the art should understand that they refer to the ability to rotate, expand, and contract the corresponding components through rotation, and do not constitute a limitation on the scope of protection of this disclosure.

[0303] For ease of describing the technical solutions of this disclosure, "connection" in this disclosure refers to the direct connection between two components, and the connection forms include at least five types of connection structures: a first type of connection structure - pivot connection, a second type of connection structure - fixed connection, a third type of connection structure - circumferentially rotatable but not sliding in the front-back direction, a fourth type of connection structure - circumferentially non-rotatable but sliding in the front-back direction, and a fifth type of connection structure - circumferentially rotatable but sliding in the front-back direction. The first type of connection structure: pivot connection, where two components are rotatably connected via a pivot, also known as hinge connection; the second type of connection structure: the fixed connection, where two components are connected by welding, riveting, or by a third component, directly or by a third component, or by integral molding; the third type of connection structure: the circumferentially rotatable but non-sliding connection is equivalent to a connection that allows relative circumferential rotation but axial positioning (axial non-sliding), for example, the first component is fitted onto the second component, the first component has a radially recessed annular groove in the circumferential direction, and the second component has a radially protruding part that inserts into the recess, or vice versa, the second component has a radially recessed annular groove in the circumferential direction, and the first component has a radially protruding part that inserts into the recess. Within the recess, the annular groove and radial protrusion engage with each other, thus restricting sliding in the front-to-back direction, while allowing rotation relative to each other; the fourth connection structure: a connection form in which relative rotation in the circumferential direction is not possible, but sliding in the front-to-back direction, for example, the first component has a radially recessed and axially extending groove, and the second component has a radially protruding and axially extending guide block, the guide block being inserted into the recess; similarly, a connection that slides in a certain direction is one in which a guide groove or guide hole is opened in a certain direction on the first component, and a protrusion on the second component is inserted into the guide groove or guide hole, so that the two can slide together in a certain direction; the fifth connection structure: the connection method in which relative rotation in the circumferential direction is possible and sliding in the front-to-back direction, for example, the first component is fitted onto the second component without any protrusions or grooves, and the two can rotate freely relative to each other and move radially.

[0304] In each embodiment, when the device is inserted into a location such as the human duodenum for ablation surgery, the defined rotating component refers to the component that rotates circumferentially relative to the duodenum during the transition of the expandable component from a contracted working state to an expanded working state, while the defined reference component is the component that does not rotate circumferentially relative to the duodenum. However, the definitions can also be reversed. Regardless of the definition, during the transition of the expandable component from a contracted working state to an expanded working state, the defined rotating component and the defined reference component are arranged to rotate relative to each other. The actively rotating component can be either the defined rotating component or the defined reference component.

[0305] The technical solution of this disclosure will now be described in conjunction with the accompanying drawings.

[0306] One technical solution disclosed herein is a device for ablation therapy of the digestive tract, comprising: The slender central conduit 2 can be a tubular body with an internal cavity forming a channel, or it can be solid. The slender outer conduit 3 is sleeved on the outside of the middle conduit 2. Of the two components, the middle conduit 2 and the outer conduit 3, one component is defined as a reference component and the other component is defined as a rotating component. The rotating component is rotatably arranged relative to the reference component. In some embodiments, the middle conduit 2 is defined as a rotating component and the outer conduit 3 is defined as a reference component. Expandable component 4 has a radially decreasing contraction working state and a radially increasing expansion working state. Expandable component 4 includes: The support frame 5 is connected to the defined rotating component, and the support frame 5 has a deformable component; the deformable component has an elastic force that causes the support frame 5 to tend to increase radially. An electrode membrane 6 is configured with electrodes 7 for receiving electrical signals. The electrode membrane is wound around the outside of a support frame 5, and its inner end 8 is connected to the support frame 5. The defined reference component is connected to the outer end of the electrode membrane 6. (Reference) Figure 12 The inner end 8 of the electrode film does not have to be an absolute end; a certain margin can be left. Similarly, the outer end 9 of the electrode film does not have to be an absolute end; a certain margin can also be left.

[0307] In some embodiments, the connection between the support frame 5 and the defined rotating component is configured to restrict circumferential rotation between them, such that when the rotating component rotates relative to the reference component, it can cause the support frame 5 to rotate relative to the reference component; and the connection between the outer end of the electrode film 6 and the defined reference component is configured to restrict circumferential rotation between them, such that when the rotating component rotates relative to the reference component, the rotating component also rotates relative to the outer end of the electrode film 6. The optimal solution for restricting the movement of two components in a certain direction (e.g., circumferential rotation) as referred to in this disclosure is to prevent misalignment in that direction (e.g., a non-rotatable circumferential arrangement), allowing them to move synchronously in that direction. In other embodiments, they may be misaligned in that direction, but the movement of either component in that direction can cause the other to move accordingly (similar to dragging an object with a rope).

[0308] In some embodiments, if the defined rotating component rotates relative to the defined reference component, the defined rotating component drives the support frame 5 to rotate relative to the defined reference component, thereby causing the inner end of the electrode membrane 6 to rotate relative to the outer end of the electrode membrane 6. The deformable component undergoes elastic deformation, causing the support frame 5 to abut against the inner surface of the electrode membrane 6, and the expandable component 4 switches between a contracted working state and an expanded working state. This device not only enables control over the expansion and contraction of the electrode membrane 6, but also ensures that the electrode membrane 6 has better radial rigidity during and after expansion.

[0309] In some embodiments, the support frame 5 is configured to be non-rotatable in the circumferential direction relative to the defined rotating component. For example, the support frame 5 is directly or indirectly fixedly connected to the rotating component by means of additional components. The corresponding connection methods will be described exemplarily in conjunction with the figures and some embodiments below.

[0310] In some embodiments, the outer end of the electrode film 6 is configured to be non-rotatable in the circumferential direction relative to the defined reference component. For example, the electrode film 6 is directly or indirectly fixedly connected to the reference component by means of additional components. The corresponding connection methods will be described exemplarily in conjunction with the figures and some embodiments later.

[0311] In some embodiments, when the expandable component 4 is in a contracted working state, the electrode film 6 and the support frame 5 are also in a radially shrinking contracted working state; when the expandable component 4 is in an expanded working state, the electrode film 6 and the support frame 5 are also in a radially expanding expanded working state.

[0312] See Figures 1 to 29-3Another technical solution disclosed herein is a device for ablation treatment of the digestive tract. The difference from the aforementioned embodiments is that this device also includes an inner guide rod 1. Specifically, the device for ablation treatment of the digestive tract includes a slender inner guide rod 1, a slender middle catheter 2, a slender outer catheter 3, and an expandable component 4. The middle catheter 2 is sleeved on the outside of the inner guide rod 1, and the outer catheter 3 is sleeved on the outside of the middle catheter 2. Among the three components—inner guide rod 1, middle catheter 2, and outer catheter 3—at least one component is defined as a reference component, and at least one other component is defined as a rotating component. The rotating component is rotatably disposed relative to the reference component. In this embodiment, the middle catheter 2 is defined as a rotating component, and the outer catheter 3 is defined as a reference component. The expandable component 4 has a radially shrinking contraction working state and a radially expanding expansion working state. The expandable component 4 includes a support frame 5 and an electrode film 6. The support frame 5 is connected to a defined rotating component. The support frame 5 has a deformable component. The deformable component has an elastic force that causes the support frame 5 to have a radially expanding tendency. The electrode membrane 6 is configured with electrodes 7 for receiving electrical signals. The electrode membrane 6 is wound around the outside of the support frame 5. The inner end of the electrode membrane 6 is connected to the support frame 5. At least one of the defined reference components is connected to the outer end of the electrode membrane 6.

[0313] In some embodiments, when the expandable component 4 is in a contracted working state, the electrode film 6 and the support frame 5 are also in a radially shrinking contracted working state; when the expandable component 4 is in an expanded working state, the electrode film 6 and the support frame 5 are also in a radially expanding expanded working state.

[0314] In some embodiments, if the defined rotating component rotates relative to the defined reference component, the defined rotating component drives the supporting frame 5 to rotate relative to the defined reference component, thereby causing the inner end of the electrode membrane 6 to rotate relative to the outer end of the electrode membrane 6. The deformable component undergoes elastic deformation, causing the supporting frame 5 to abut against the inner surface of the electrode membrane 6, and the expandable component 4 switches between a contracted working state and an expanded working state. The device for ablation treatment of the digestive tract equipped with this expandable component 4 can not only control the expansion and contraction of the electrode membrane 6, but also ensure that the electrode membrane 6 has better rigidity during and after expansion.

[0315] In the three components—inner guide rod 1, middle guide tube 2, and outer guide tube 3—for example, when the outer guide tube 3 is defined as a reference component and the middle guide tube 2 is defined as a rotating component, the middle guide tube 2 is rotatably arranged relative to the outer guide tube 3, while the outer guide tube 3 is fixedly connected relative to the inner guide rod 1. This device not only enables control over the expansion and contraction of the electrode membrane 6 but also ensures better radial outward rigidity of the electrode membrane 6 during and after expansion. The inner guide rod can be a tubular body with a channel forming an internal cavity, or it can be solid.

[0316] Another technical solution disclosed herein is an expandable component 4 of a device for ablation therapy of the digestive tract. The expandable component 4 has a radially shrinking contraction working state and a radially enlarging expansion working state. The expandable component 4 includes a support frame 5 and an electrode membrane 6. The support frame 5 has a deformable component; the deformable component has an elastic force that causes the support frame 5 to tend to expand radially. The support frame 5 is used to connect with a defined rotating component. The electrode membrane 6 is configured with electrodes 7 for receiving electrical signals. The electrode membrane 6 is wound around the outside of the support frame 5. The inner end of the electrode membrane 6 is connected to the support frame 5, and the outer end of the electrode membrane 6 is configured to connect with a defined reference component. The rotating component is rotatably disposed relative to the reference component, and the outer end of the electrode membrane 6 is not rotatably disposed relative to the defined reference component in the circumferential direction.

[0317] In some embodiments, when the expandable component 4 is in a contracted working state, the electrode film 6 and the support frame 5 are also in a radially shrinking contracted working state; when the expandable component 4 is in an expanded working state, the electrode film 6 and the support frame 5 are also in a radially expanding expanded working state.

[0318] In some embodiments, if the defined rotating component rotates relative to the defined reference component, the defined rotating component drives the support frame 5 to rotate, and the inner end of the electrode film 6 rotates relative to the outer end of the electrode film 6. The deformable component undergoes elastic deformation so that the support frame 5 abuts against the inner side of the electrode film 6, and the expandable component 4 switches between a contracted working state and an expanded working state.

[0319] The support frame 5 disclosed herein has an expanding working state and a contracting working state. In the expanding working state, the outer edge of the middle part of the support frame 5 expands radially outward, and in the contracting working state, the outer edge of the middle part of the support frame 5 contracts radially inward. The support frame 5 has a deformable component, which has an elastic force that causes the support frame 5 to tend to expand radially. The deformable component can be made of an elastic material (e.g., titanium-nickel alloy), an elastic structure (e.g., an external component torsion spring, a localized molding structure of the support frame 5, etc.), or a combination of both to provide the required elastic force. The deformable component can be a locally provided structure, material, or additional component of the support frame 5, or the entire support frame 5 can be elastic, in which case the entire support frame 5 is the deformable component. When the support frame 5 is in either of the two working states, certain rigid rods (or components, such as the inner support rod 24) on the support frame 5 are elastic and will change shape. In the contracting working state, these deformable components are compressed by the binding force of the electrode film 6, generating potential energy, so that the support frame 5 always tends to change towards the expanding working state. When the diameter of the electrode film 6 increases, the deformation component of the support frame 5 causes the potential energy generated during compression to be converted into the kinetic energy of part of the support frame 5 structure. At this time, the support frame 5 changes to an expansion working state.

[0320] The support frame 5 is divided into two main categories. The first category consists of structures where the support frame 5 exhibits local axial displacement during the transition between working states. For example, when the support frame 5 is positioned around the inner guide rod 1, if the front end of the support frame 5 is farther away from the rear end, the radial distance between the outer edge of the middle section of the support frame 5 and the inner guide rod 1 decreases, indicating that the support frame 5 is in a contracted working state, retracting around the inner guide rod 1. Conversely, when the front end of the support frame 5 is closer to the rear end, the radial distance between the outer edge of the middle section of the support frame 5 and the inner guide rod 1 increases, indicating that the support frame 5 is in an expanded working state. However, in certain modified support frames (e.g., ...), ... Figure 22-1When the inner support rod 24 is transformed into a semicircle with an arc greater than 180 degrees, and the front end of the support frame 5 is closer to the rear end of the support frame 5, the distance from the outer edge of the middle section of the support frame 5 to the inner guide rod 1 decreases radially, that is, the support frame 5 is in a contracted working state, and at this time the support frame 5 is contracted around the inner guide rod 1; when the front end of the support frame 5 is farther from the rear end of the support frame 5, the distance from the outer edge of the middle section of the support frame 5 to the inner guide rod 1 increases radially, and the support frame 5 is in an expanded working state. When the support frame 5 is arranged around the middle guide tube 2, the above description of the support frame 5 can also be referred to. Therefore, in this disclosure, the front end and the rear end of the support frame 5 refer to the ends of the support frame 5 that are close to or in contact with the inner guide rod 1 or the middle guide tube 2. In some cases, the front end of the support frame is also the front connecting ring 12, and the rear end of the support frame is also the rear connecting ring 13. In this case, the structures that undergo axial displacement are the front connecting ring 12 and the rear connecting ring 13. The front connecting ring 12 and / or the rear connecting ring 13 can be integrally formed with the support frame 5, in which case the front connecting ring 12 and / or the rear connecting ring 13 are part of the support frame 5; of course, the front connecting ring 12 and / or the rear connecting ring 13 can also be external components connected to the support frame 5 by means of pivot connection or fixed connection, etc.

[0321] The second major category of support frame 5 is: the inner side of the support frame 5 does not have relatively movable ends. For example, the inner side of the support frame 5 is fixedly connected to the middle guide tube 2 or at least does not undergo axial displacement. This type of support frame 5 does not have two relatively movable ends that contact the inner guide rod 1 or the outer guide tube 2, and only relies on the outer side of the support frame 5 to radially approach or radially move away from the middle guide tube 2 to form a contraction working state or an expansion working state. For example... Figure 35-1 , Figure 35-2 , Figure 36-1 , 36-2 As shown.

[0322] Therefore, the supporting framework referred to in this disclosure includes, but is not limited to, the structures expressed in the various embodiments of this disclosure.

[0323] The device for ablation therapy of the digestive tract also includes an actuator connected to the rotating component, which drives the rotating component to rotate relative to the reference component. In some embodiments, of the two components, the middle catheter 2 and the outer catheter 3, one component (e.g., the outer catheter 3) is defined as the reference component, and the other component (e.g., the middle catheter 2) is defined as the rotating component. The defined rotating component is rotatably disposed relative to the defined reference component. The actuator is connected to the support frame 5 via the middle catheter 2. The rotation of the actuator directly drives the rotation of the middle catheter 2, which in turn drives the rotation of the support frame 5. Consequently, the inner end 8 of the electrode membrane wrapped around the outside of the support frame 5 also rotates, causing a change in the diameter of the electrode membrane 6. The actuator drives the inner end 8 of the electrode membrane to rotate, reducing the frictional resistance of the surrounding tissue to the electrode membrane 6. The actuator is easy to drive and will not damage the inner wall of the digestive tract. The actuator and the scheme of using a driver to drive the rotating component can adopt existing schemes in the prior art.

[0324] In other embodiments, the actuator is connected to the connector via an outer conduit 3. The rotation of the actuator can directly drive the outer conduit 3 to rotate, which in turn drives the outer end 9 of the electrode membrane to rotate via the connector, thus changing the diameter of the electrode membrane 6. The actuator effectively drives the outer end 9 of the electrode membrane to rotate directly, making the actuator's operation less strenuous.

[0325] The connector includes an electrode membrane connector and a deformable connector that is rigid in the circumferential direction. The electrode membrane connector is parallel to the central conduit 2 and connected to the outer end of the electrode membrane 6. In some embodiments, the electrode membrane connector is an outer end rod 14, and the deformable connector is a connecting strip 15. The front end of the deformable connector is connected to the rear end of the electrode membrane connector, and the connection between the front end of the deformable connector and the rear end of the electrode membrane connector is selected from the following connection structures: pivot connection, fixed connection, slidable connection in the front-rear direction, and pivotal and slidable connection, wherein the pivot of the pivotal connection is perpendicular to the central conduit 2. The rear end of the deformable connector is connected to the outer conduit 3, and the connection between the rear end of the deformable connector and the outer conduit 3 is selected from the following connection structures: pivot connection, fixed connection, slidable connection in the front-rear direction, and pivotal and slidable connection, wherein the pivot of the pivotal connection is perpendicular to the central conduit 2.

[0326] During the transition from a contracted to an expanded working state of the support frame, the electrode membrane connector gradually moves away from the central conduit 2; conversely, during the transition from an expanded to a contracted working state, the electrode membrane connector gradually moves closer to the central conduit 2. In some embodiments, the distance between the front and rear ends of the deformable connector is variably set when the support frame 5 transitions between the contracted and expanded working states. In some embodiments, the electrode membrane connector is a rigid rod (such as the outer end rod 14), whose length in the front-rear direction is equal to or substantially equal to the length of the electrode membrane 6 in the front-rear direction, so as to provide stable support and connection for the electrode membrane 6.

[0327] See Figures 1 to 29-3 This embodiment provides a device for ablation therapy of the digestive tract, which includes: In some variations, the slender inner guide rod 1 is a slender tubular component with an axial guidewire lumen 30, which is used for the passage of the guidewire during surgery. A slender central guide tube 2 is sleeved on an inner guide rod 1, and the central guide tube 2 is rotatably arranged relative to the inner guide rod 1, with the inner guide rod 1 serving as the rotation axis of the central guide tube 2. The slender outer conduit 3 is sleeved on the middle conduit 2, and the middle conduit 2 is rotatably arranged relative to the outer conduit 3. The outer conduit 3 is fixed relative to the inner guide rod 1. When the middle conduit 2 rotates relative to the inner guide rod 1, the middle conduit 2 also rotates inside the outer conduit 3. In some embodiments, the middle conduit 2 is defined as a rotating component, and the outer conduit 3 is defined as a reference component. The rotating component is rotatably disposed relative to the reference component, and the connection relationship between the outer conduit 3 and the middle conduit 2, and the connection relationship between the outer conduit 3 and the inner guide rod 1, are not limited. In some embodiments, the outer conduit 3 is fixedly connected to the inner guide rod 1. Therefore, the middle conduit 2 is rotatably disposed relative to the outer conduit 3, and in this case, the outer conduit 3 can also be regarded as the reference component.

[0328] The expandable component 4 surrounds the inner guide rod 1. The expandable component 4 includes a support frame 5 and a flexible electrode membrane 6. The expandable component 4 has a radially shrinking contraction working state and a radially expanding expansion working state. The rear end of the support frame 5 is connected to the front end of the middle guide tube 2. Figures 1 to 8 , Figures 10 to 12 The image shows the support frame 5 of Embodiment 1. Figures 13 to 20 This illustrates the support frame 5 of Embodiment 2. In embodiments with two support frames 5, the rear end of the support frame 5 is directly and fixedly connected to the front end of the central conduit 2. However, in some variations, a connection structure other than the third connection structure described above can be used. When using the first connection structure (e.g.) Figures 22-1 to 22-3As shown in the diagram, the axis of the pivot should be spatially perpendicular to the inner guide rod 1. This is so that when the middle guide tube 2 rotates relative to the inner guide rod 1, the middle guide tube 2 drives the support frame 5 to rotate (or rotate synchronously), causing the support frame 5 to rotate around the inner guide rod 1. When the front end of the support frame 5 is far away from the rear end, the radial distance between the middle section of the support frame 5 and the inner guide rod 1 decreases, meaning the support frame 5 is in a contracted working state, retracting around the inner guide rod 1. When the front end of the support frame 5 is close to the rear end, the radial distance between the middle section of the support frame 5 and the inner guide rod 1 increases, meaning the support frame 5 is in an expanding working state. In this disclosure, the expanding working state of the support frame 5 refers to the radial expansion of the support frame 5 towards the outside of the inner guide rod 1. The support frame 5 shown in this disclosure is only a partial embodiment; some modified structures can also be used as the support frame in this disclosure.

[0329] Referring to the figures, the electrode membrane 6 is provided with multiple electrodes 7 for receiving electrical signals. The electrode membrane 6 is wound (in this embodiment, in a spiral shape) on the support frame 5. When the support frame 5 is in a contracted working state, the electrode membrane 6 is also in a contracted working state, and the expandable component 4 is in a contracted working state, as shown in the figures. Figure 12 and Figure 18 As shown, the electrode membrane 6 is wound in multiple turns on the support frame 5. Each outer ring of the electrode membrane 6 is tightly attached to the inner ring of the electrode membrane 6, with a cross-section resembling a spiral spring. That is, adjacent rings of the electrode membrane 6 are tightly attached, and the front sides of each ring of the electrode membrane 6 are basically aligned, as are the rear sides, i.e., they are wound in a spiral shape on the outside of the support frame 5. In some embodiments, the front and / or rear sides of each ring of the electrode membrane 6 may be significantly misaligned according to actual needs (e.g., shifted forward or backward layer by layer from the inside out, or the rings of the electrode membrane 6 are irregularly misaligned). The inner end 8 of the electrode membrane (i.e., the edge portion of the innermost ring of the electrode membrane 6) is fixedly or rotatably connected to the support frame 5, and the outer end 9 of the electrode membrane (i.e., the edge portion of the outermost ring of the electrode membrane 6) is fixedly or rotatably connected to the outer conduit 3 through a connector. The inner end 8 of the electrode membrane is parallel to the inner guide rod 1, and the outer end 9 of the electrode membrane is also parallel to the inner guide rod 1. The front edges of each ring of the electrode membrane 6 are aligned, and the rear edges of each ring of the electrode membrane 6 are also aligned. As the support frame 5 transitions from its retracted working state... Figure 11 or Figure 17 During the expansion working state transition shown, the electrode membrane 6 also transitions from a contracted working state to an expanded working state. After expansion, the total number of turns of the electrode membrane 6 decreases, and the diameter of each turn of the electrode membrane 6 increases. Ultimately, when the support frame 5 is in the expanded working state, in a limiting state, the number of turns of the electrode membrane 6 is greater than 1 turn but less than 2 turns, as shown. Figure 11 or Figure 17As shown. Of course, the degree of expansion of the support frame 5 can be determined according to the actual use scenario (e.g., partial expansion working state) to adapt to the diameter of the inner wall of the corresponding digestive tract. In the expanded working state, the support frame 5 supports the electrode membrane 6. The outermost cylindrical electrode membrane 6 can be stretched and pressed against the inner wall of the digestive tract, especially the inner wall of the duodenum. After receiving the electrical pulse from the signal generator 31, the electrode 7 discharges to ablate the inner wall tissue. The electrical signals generated by the signal generator 31 include electrical signals for heating the target tissue, pulse signals for electric field ablation of the target tissue, radiofrequency ablation signals, etc. The signal generator 31 and the method of transmitting electrical signals from the signal generator 31 to the electrode 7 can both adopt existing technologies.

[0330] In some embodiments, the deformable component of the support frame 5 during the transition between the contracted and expanded working states is made of a shape memory alloy, stainless steel, or an elastic plastic. Examples include shape memory alloys such as elastic nickel-titanium alloys, elastic stainless steel, and elastic plastics (e.g., certain hard plastics with good elasticity and non-toxic to humans). The deformable component can be integrally formed with the support frame 5, in which case it is a part of the support frame 5. In some embodiments, the deformable component can be a separate component connected to the support frame 5, such as a torsion spring. The deformable component is a component of the support frame 5 whose shape changes between the two working states, for example... Figure 14 The shapes of the inner support rod 24 and the middle support rod 25 have changed; for example... Figure 4 In the middle, the shape of the inner support rod 24 is changed. The shape of the support frame 5 in the expansion working state is the preset shape of the corresponding material of the deformable part (such as the shape memory alloy material). The shape memory makes the support frame 5 always have a radially outward elastic force to transition from the contraction working state to the expansion working state, so that the support frame 5 always applies a radially outward elastic force to the electrode film 6.

[0331] As the rotating conduit 2 drives the supporting frame 5 to rotate relative to the outer conduit 3 around the inner guide rod 1, the outer end 9 of the electrode membrane is positioned in the front-rear direction by the connector and is only allowed to move radially. That is, the outer end 9 of the electrode membrane is positioned in the front-rear direction but is radially movable. The inner end 8 of the electrode membrane rotates around the inner guide rod 1 under the drive of the supporting frame 5, thus gradually reducing the total number of turns of the electrode membrane 6. Correspondingly, each turn of the electrode membrane 6 is stretched open by the radially outward elastic force of the supporting frame 5. Therefore, the preset memory shape causes the supporting frame 5 to transition from a contracted working state to an expanded working state, and the diameter of the electrode membrane 6 gradually expands. The expandable component 4... Figure 2 State transition Figure 4The state, or the expandable component 4 is composed of Figure 16 State transition Figure 14 The state of rotation of the guide tube 2, which drives the support frame 5 to rotate in the opposite direction to the outer guide tube 3 with the inner guide rod 1 as the rotation axis, gradually increases the total number of turns of the electrode membrane 6, and gradually shrinks the diameter of the electrode membrane 6. The electrode membrane 6 applies a radially inward force to the support frame 5, which overcomes the elastic force of the preset memory shape, causing the support frame 5 to switch from the expansion working state to the contraction working state.

[0332] Therefore, regardless of whether the supporting frame 5 is in a contracted working state, an expanded working state, or during the transition between the two working states, the electrode membrane 6 always tightly grips the supporting frame 5, ensuring that the innermost ring of the electrode membrane 6 is always firmly attached to the supporting frame 5, and that adjacent rings of the electrode membrane 6 are also always firmly attached to each other. Depending on the different diameters of the patient's intestine, the supporting frame 5 can support electrode membranes 6 of different diameters in both partially expanded and fully expanded working states, allowing the outermost ring of the electrode membrane 6 to expand and adhere tightly to the inner wall of the intestine. Under the action of the pulse signal from the signal generator 31, the discharge of the electrode 7 can accurately ablate the villi of the intestinal wall.

[0333] See Figure 4 or Figure 14 The front end of the support frame 5 is a front connecting ring 12, which is slidably and rotatably fitted onto the inner guide rod 1 in the front-back direction. When the support frame 5 transitions from a contracted working state to an expanded working state, the front connecting ring 12 rotates around the inner guide rod 1 and slides backward along the inner guide rod 1. In some modified structures, the front connecting ring 12 is pivotally connected to the front middle part of the support frame 5, and the front connecting ring 12 is slidably and rotatably fitted onto the inner guide rod 1 in the front-back direction (not shown). The rear end of the support frame 5 is a rear connecting ring 13, which is fitted onto the inner guide rod 1 and fixedly connected to the middle guide tube 2. The middle guide tube 2 drives the support frame 5 to rotate, but the middle guide tube 2 can only rotate relative to the inner guide rod 1 and cannot move in the front-back direction relative to the inner guide rod 1. In some modified structures, the rear connecting ring 13 is omitted, and the rear end of the support frame 5 is directly fixedly connected to the middle guide tube 2. In some variant structures, the rear central pivot of the supporting frame 5 is on the rear connecting ring 13 (not shown), and the rear connecting ring 13 is then fixedly connected to the central guide tube 2. In some embodiments, the front connecting ring 12 and / or the rear connecting ring 13 are rings with a through hole in the middle, which are fully enclosed or not fully enclosed structures. They can also be structures with two states: an open, ready-to-install state (in which case the ring has an opening, which facilitates the installation of the ring to the outside of a component such as the inner guide rod 1) and a closed or semi-closed installation state (in which case the opening of the ring is basically closed, and the ring is held to the outside of a component such as the inner guide rod 1).

[0334] When the support frame 5 contracts or expands, the inner end 8 of the electrode membrane, being fixed to the support frame 5, rotates around the inner guide rod 1 along with the support frame 5. The connector is connected to the outer conduit 3. When the outer conduit 3 is fixedly connected to the inner guide rod 1, there is no relative movement between the outer conduit 3 and the inner guide rod 1. Therefore, the connector prevents the outer end 9 of the electrode membrane from rotating around the inner guide rod 1. However, since the diameter of the electrode membrane 6 always matches the support frame 5, the connector also allows the outer end 9 of the electrode membrane to move radially. See also... Figure 14 The connector includes an outer end rod 14 (i.e., an electrode membrane connector) and an integral strip-shaped connecting strip 15 (i.e., a deformable connector) that is fixedly or rotatably connected to the rear end of the outer end rod 14. The rear end of the connecting strip 15 is connected to the front end of the outer conduit 3. The connection structure excludes a third connection structure. The outer end rod 14 is fixedly or rotatably connected to the outer end 9 of the electrode membrane. The connecting strip 15 is used to prevent (or prevent, as will be the case hereafter) the outer end rod 14 from rotating around the inner guide rod 1 and / or the middle conduit 2.

[0335] In some variant structures, reference Figure 22-4 and Figure 23 The connector includes an outer end rod 14 and a connecting strip 15 connected to the front end of the outer end rod 14. The front end of the connecting strip 15 is connected to the front of the inner guide rod 1. The outer end rod 14 is fixedly or rotatably connected to the outer end 9 of the electrode film. The front end of the connecting strip 15 has a groove (not shown in the figure) extending in the front-rear direction and cooperating with a first axial protrusion 46 on the inner guide rod 1, so that the front end of the connecting strip 15 can slide along the front-rear direction of the inner guide rod 1 but is prohibited from rotating in the relative circumferential direction. In some variations, the front end of the connecting strip 15 may also be fixedly connected to the inner guide rod 1 or pivotally connected, but the pivot should be perpendicular to the inner guide rod 1.

[0336] See Figure 29-1 In a preferred embodiment, the connector includes an outer end rod 14, a front connecting strip 15 connected to the front end of the outer end rod 14, and a rear connecting strip 15 connected to the rear end of the outer end rod 14. The front end of the front connecting strip 15 is connected to the inner guide rod 1, and the rear end of the rear connecting strip 15 is connected to the outer conduit 3. The connecting strip 15 is axially and non-rotatably connected to the inner guide rod 1 or the outer conduit 3. In this embodiment, the connection between the connecting strip 15 and the inner guide rod 1 or the outer conduit 3 is a connection structure other than the third type of connection structure. The outer end rod 14 is fixedly or rotatably connected to the outer end 9 of the electrode membrane. That is, the connector connects the outer end 9 of the electrode membrane, the inner guide rod 1, and the outer conduit 3, which can make the outer end 9 of the electrode membrane subjected to balanced forces in the front-back direction. It will not be twisted due to the force because only one end of the outer end rod 14 is connected to the inner guide rod 1 or the outer conduit 3, ensuring that the outer end rod 14 is always approximately parallel to the inner guide rod 1, and that the outer end rod 14 does not move in the front-back direction.

[0337] During the transition of the support frame 5 from the contracted working state to the expanded working state, as the diameter of each ring of electrode membrane 6 increases, the outer end rod 14 gradually moves away from the inner guide rod 1. During the transition of the support frame 5 from the expanded working state to the contracted working state, as the diameter of each ring of electrode membrane 6 decreases, the outer end rod 14 gradually moves closer to the inner guide rod 1, and the outer end rod 14 is always approximately parallel to the inner guide rod 1.

[0338] When the support frame 5 changes between the contracted and expanded working states, the straight-line distance between the rear end of the connecting strip 15 and the rear connecting ring 13, acting as the leg of a virtual right triangle, remains constant. The straight-line distance between the outer end 9 of the electrode film and the rear connecting ring 13, also acting as the other leg of a virtual right triangle, changes. The distance between the rear end and the front end of the connecting strip 15, acting as the hypotenuse of a virtual right triangle, also changes. When the support frame 5 is in the contracted working state, the hypotenuse shortens; when the support frame 5 is in the expanded working state, the hypotenuse length increases. To accommodate this change, in some variant structures, the connecting strip 15 is a rigid elastic sheet capable of elastic bending (see...). Figure 29-2 The rear end of the rigid elastic sheet is fixed (or pivotally) connected to the outer guide tube 3, and the front end of the rigid elastic sheet is fixed (or pivotally) connected to the rear end of the outer end rod 14. When the support frame 5 is in the contracted working state, the rigid elastic sheet is bent inward or outward. When the support frame 5 is in the expanded working state, the rigid elastic sheet is straight. However, some bending is also acceptable (i.e., basically straight) so as to simplify the structure and reduce interference to the outside of the device when in the expanded working state.

[0339] In some variant structures, such as Figure 4 As shown, the connecting bar 15 includes multiple sections (two or more, for example, two sections) of rod 17. The front end of the adjacent subsequent rod 17 is pivotally connected to the rear end of the preceding rod 17 to form a chain. The front end of the foremost rod 17 is pivotally connected to the rear end of the outer rod 14. The rear end of the last rod 17 is pivotally connected to the outer guide tube 3. The axis of each pivot is perpendicular to the inner guide rod 1 in space. When the support frame 5 is in the contracted working state, the connecting bar 15 is bent inward or outward. When the support frame 5 is in the expanded working state, the connecting bar 15 is generally straight.

[0340] In some variant structures (such as) Figure 29-3As shown), the connecting bar 15 includes multiple sections (two or more, such as three sections) of rod 17. Adjacent sections of rod 17 are slidably connected to form a telescopic rod, allowing for extension and retraction between adjacent sections of rod 17. The front end of the first section of rod 17 is pivotally connected to the rear end of the outer end rod 14, and the rear end of the last section of rod 17 is pivotally connected to the outer guide tube 3. The centerline of each pivot is spatially perpendicular to the inner guide rod 1. Specifically, Figure 29-3 In the middle section 17, there is a first guide groove 37 and a second guide groove 38. Two adjacent sections 17 each have a long strip of guide protrusion (not shown in the figure). The long strips of guide protrusion on the two adjacent sections 17 are respectively inserted into the first guide groove 37 and the second guide groove 38 to form a sliding connection.

[0341] If the connecting strip 15 is at least partially (e.g., at the connection with the inner guide rod 1 or the connection with the outer conduit 3) selected as a rigid rod, then the connecting strip 15 can also be connected to the inner guide rod 1 or the outer conduit 3. In this case, an axially extending rib or guide groove (e.g., in the front-to-back direction) needs to be provided on the inner guide rod 1 or the outer conduit 3. Figure 29-1 In the middle, the first axial protrusion 46 on the inner guide rod 1 is equipped with a guide block that cooperates with the first axial protrusion 46. The guide block can only slide along the front and back direction of the first axial protrusion 46 but cannot rotate. One end of the rigid rod is pivotally connected to the guide block.

[0342] See Figures 22-1 to 22-3 A modified structure of the support frame in Embodiment 1, wherein the front middle part of the support frame 5 is rotatably connected to a front connecting ring 12 via a pivot 18, and the rear middle part of the support frame 5 is rotatably connected to a rear connecting ring 13 via a pivot 18. Figures 22-1 to 22-3 In the middle, the inner support frame 19 includes multiple inner support rods 24. The front end of each inner support rod 24 is rotatably connected to the front connecting ring 12 via a pivot 18, and the rear end of each inner support rod 24 is rotatably connected to the rear connecting ring 13 via a pivot 18. Each pivot 18 is spatially perpendicular to the inner guide rod 1 or the middle guide tube 2.

[0343] Similarly, Figure 14 The modified structure of the support frame embodiment 2 shown (not illustrated) can be referenced to the modified structure of the support frame embodiment 1 described above. The front middle portion of the support frame 5 is rotatably connected to a front connecting ring 12 via a pivot 18, and the rear middle portion of the support frame 5 is rotatably connected to a rear connecting ring 13 via a pivot 18. Specifically, the inner support frame 19 includes multiple inner support rods 24. The front end of each inner support rod 24 is rotatably connected to the front connecting ring 12 via a pivot 18, and the rear end of each inner support rod 24 is rotatably connected to the rear connecting ring 13 via a pivot 18. Each pivot 18 is spatially perpendicular to the inner guide rod 1 or the middle guide tube 2.

[0344] In summary, in some embodiments, the support frame 5 deforms when it changes between a contracted working state and an expanded working state (e.g., Figure 8 The inner support rod 24 (at its bend) is made of a rigid elastic material (i.e., a rigid material with elasticity, such as titanium-nickel alloy or stainless steel). This rigid elastic material gives the support frame 5 a radially outward elastic force that allows it to change from a contracted working state to an expanded working state. The electrode membrane 6 is provided with multiple electrodes 7 for receiving electrical signals. The electrode membrane 6 is wound around the support frame 5; preferably, the electrode membrane 6 is wound in a spiral shape around the support frame 5. The inner end 8 of the electrode membrane is fixedly connected to the support frame 5. The outer end 9 of the electrode membrane is connected to the outer conduit 3 via a connector. In some variations, for example… Figure 22-4 The outer end 9 of the electrode film is connected to the front part of the inner guide rod 1 via a connector. In some variations, for example... Figure 29-1 The outer end 9 of the electrode membrane is connected to both the front of the outer conduit 3 and the front of the inner guide rod 1 via a connector, which can prevent the outer end 9 of the electrode membrane from twisting and moving in the front and back directions.

[0345] refer to Figure 1 The actuator is an operating handle 28, which is connected to the middle conduit 2 and / or the outer conduit 3, and can also be connected to the inner guide rod 1. The actuator is used to drive the middle conduit 2 and / or the outer conduit 3, so that the middle conduit 2 rotates in the forward direction relative to the outer conduit 3. The middle conduit 2 drives the support frame 6 to rotate in the forward direction, so that the electrode membrane 6 expands radially, and the support frame 5 also expands radially under the action of the rigid elastic material. The actuator is also used to drive the middle conduit 2 and / or the outer conduit 3, so that the middle conduit 2 rotates in the reverse direction relative to the outer conduit 3. The electrode membrane 6 contracts radially, and the electrode membrane 6 compresses and tightens the support frame 5 to contract radially.

[0346] In some modified structures, the actuator is connected to the middle catheter 2 and is used to drive the support frame 5 to rotate relative to the outer catheter 3 when the middle catheter 2 rotates relative to the outer catheter 3. The inner end 8 of the electrode membrane on the support frame 5 rotates relative to the outer end 9 of the electrode membrane. In the human digestive tract, when the electrode membrane 6 expands or contracts, the outermost electrode membrane 6 moves radially but does not rotate, which is less likely to damage the intestinal wall and reduces the resistance encountered during expansion or contraction, making operation more convenient.

[0347] The structure of an actuator will now be described with reference to the figures. One embodiment is shown below. Figure 1 , Figure 9 and Figure 21 , Figure 37-1 , Figure 37-3The actuator includes an internal gear 10, an intermediate gear 11, and a knob 34, which are rotating components. The middle guide tube 2 is fixedly connected to the rotating component on the operating handle 28. The rotating component can rotate relative to the operating handle body 35. Since both the inner guide rod 1 and the outer guide tube 3 are fixedly connected to the operating handle body 35, the rotating component can drive the middle guide tube 2 to rotate relative to the outer guide tube 3. Figure 9 Inside the operating handle 28, the rotating component is an internal gear 10, which is limited in the front-to-back direction by the operating handle body 35. Therefore, the inner guide rod 1 and the middle guide tube 2 are relatively fixed in position in the front-to-back direction, and the outer guide tube 3 and the middle guide tube 2 are also relatively fixed in position in the front-to-back direction. The inner guide rod 1 and the outer guide tube 3 are also relatively fixed. See also Figure 9 and Figure 21 The inner guide rod 1 is fixedly connected to the operating handle body 35, and the outer guide tube 3 is also fixedly connected to the operating handle body 35. A knob 34 is rotatably connected to the operating handle body 35. The inner wall of the knob 34 has an internal gear ring 16. An internal gear 10 is pivotally connected to the operating handle body 35, and the internal gear 10 is fixedly connected to the middle guide tube 2. Two intermediate gears 11, pivotally connected to the operating handle body 35, are meshed on the internal gear 10. The intermediate gears 11 mesh with the internal gear ring 16. Rotation of the knob 34 drives the internal gear 10 to rotate, thereby causing the middle guide tube 2 to rotate relative to the handle body 35. As mentioned earlier, since both the inner guide rod 1 and the outer guide tube 3 are fixedly connected to the operating handle body 35, the middle guide tube 2 also rotates relative to the inner guide rod 1 and the outer guide tube 3.

[0348] In some modified structures, the middle conduit 2, serving as a rotating component, and the outer conduit 3, serving as a reference component, are rotatably arranged relative to the reference component. The component that is actively rotated is the outer conduit 3, which serves as the reference component. In this case, an actuator is connected to the outer conduit 3 to drive the connector to rotate around the support frame 5 when the outer conduit 3 rotates relative to the middle conduit 2. The outer end 9 of the electrode membrane on the support frame 5 rotates relative to the inner end 8 of the electrode membrane, thereby controlling the expansion or contraction of the support frame 5. In the human digestive tract, when the electrode membrane 6 expands or contracts, the outermost electrode membrane 6 moves radially and rotates around the support frame 5. When the electrode membrane 6 rotates, the friction generated by its contact with the inner wall of the intestine requires an increase in the driving force of the actuator, as well as the elastic force of the rigid elastic material (or deformable component).

[0349] Specifically, when the actuator drives the outer conduit 3 to rotate in the opposite direction relative to the middle conduit 2, the outer conduit 3 drives the outer end 9 of the connector and electrode membrane to rotate in the opposite direction, causing the electrode membrane 6 to expand radially while the supporting frame 5 also expands radially under the action of the elastic material; when the actuator drives the outer conduit 3 to rotate in the forward direction relative to the middle conduit 2, the outer conduit 3 drives the outer end 9 of the connector and electrode membrane to rotate in the forward direction, causing the electrode membrane 6 to contract radially while simultaneously compressing and tightening the supporting frame 5 in a radial contraction. See also Figures 24-26 The tail of the inner guide rod 1 is fixedly connected to the rear end of the operating handle body 35. The middle guide tube 2 is fixedly connected to the knob 34 and can be driven to rotate by the knob 34. A first bevel gear 39 is also coaxially fixed on the middle guide tube 2. The first bevel gear 39 meshes with the second bevel gear 40. The second bevel gear 40 meshes with the third bevel gear 41. An outer guide tube 3 is coaxially fixed on the third bevel gear 41. The rotation direction of the third bevel gear 41 is opposite to the rotation direction of the first bevel gear 39, so that when the knob 34 drives the middle guide tube 2 to rotate, the outer guide tube 3 also rotates in the opposite direction at the same time.

[0350] In some modified structures, the inner guide rod 1 and the middle guide tube 2 are positioned relatively fixed in the front-to-back direction, but relative rotation between them is permitted; that is, the inner guide rod 1 is rotatably mounted relative to the middle guide tube 2. (Corresponding structural reference) Figure 5 and Figure 21 ,or Figure 25 and Figure 26 Within the operating handle 28, the inner guide rod 1 is fixed to the operating handle body 35, and the middle guide tube 2 is fixed to the rotating component within the operating handle 28. The rotating component is limited by a limiting component and cannot move in the front-to-back direction. In some variant structures, a radially inward annular protrusion may be provided on the inner wall of the middle guide tube 2, which inserts into a radially inward annular recessed groove on the outer wall of the inner guide rod 1. In some variant structures, a radially outward annular recessed groove may be provided on the inner wall of the middle guide tube 2, and a radially outward annular protrusion may be provided on the outer wall of the inner guide rod 1, which inserts into the recessed groove.

[0351] In some modified structures, the outer conduit 3 and the middle conduit 2 are positioned relatively fixed in the front-back direction, but the middle conduit 2 and the outer conduit 3 are allowed to rotate relative to each other (i.e., the middle conduit 2 is rotatably positioned relative to the outer conduit 3). The corresponding structural reference is... Figure 5 and Figure 21Within the operating handle 28, the outer conduit 3 is fixed to the operating handle body 35, and the middle conduit 2 is fixed to a rotating component within the operating handle 28. The rotating component is limited by a limiting component and cannot move in the front-to-back direction. In some variant structures, a radially inward annular protrusion may be provided on the inner wall of the outer conduit 3, which inserts into a radially inward annular recessed groove on the outer wall of the middle conduit 2. In some variant structures, a radially outward annular recessed groove may be provided on the inner wall of the outer conduit 3, and a radially outward annular protrusion may be provided on the outer wall of the middle conduit 2, which inserts into the recessed groove. In some variant structures, refer to... Figure 25 and Figure 26 The outer catheter 3 is restricted by the first limiting member 44 and cannot move relative to the middle catheter 2 in the front-back direction. The middle catheter 2 is restricted by the second limiting member 45 and cannot move relative to the outer catheter 3 in the front-back direction.

[0352] In some variant structures, see Figure 27 and Figure 28 The support frame 5 has a front end and a rear end. The front end is a front connecting ring 12, and the rear end is a rear connecting ring 13. The front connecting ring 12 is sleeved on the inner guide rod 1 and is rotatably and positionally positioned on the inner guide rod 1 in the front-rear direction. Specifically, the front part of the inner guide rod 1 has a radially outward annular protrusion 42, which is inserted into the annular groove of the front connecting ring 12. The rear connecting ring 13 is sleeved on the middle guide tube 2, and the rear end of the support frame and the middle guide tube 2 are slidably arranged in the front-rear direction but are prohibited from relative rotation. Specifically, the middle guide tube 2 has a second axial rib 47 extending in the front-rear direction, which protrudes radially outward. The rear connecting ring 13 has a guide groove extending in the front-rear direction, and the second axial rib 47 is inserted into the groove. When the middle conduit 2 rotates, it drives the supporting frame 5 to rotate. The front connecting ring 12 rotates relative to the inner guide rod 1 without sliding axially. The rear connecting ring 13 rotates along with the middle conduit 2 and slides axially on the middle conduit 2. The rear connecting ring 13 slides relative to the middle conduit 2 without rotating.

[0353] In some modified structures (not shown), the support frame 5 has a front end and a rear end. The front end of the support frame is sleeved on the inner guide rod 1. The front end of the support frame is a movable end that is movable relative to the inner guide rod 1 in both the front-back direction and the circumferential direction. The rear end of the support frame 5 is connected to the middle guide tube 2. The rear end of the support frame 5 and the middle guide tube 2 are slidably but non-rotatable in the front-back direction.

[0354] See Figure 4 , Figure 22-4 , Figure 27One embodiment of the support frame 5 includes an inner support frame 19 and multiple outer support rods 20. The front end of the inner support frame 19 is a front connecting ring 12, which is slidably fitted onto the inner guide rod 1 in the front-back direction. The rear end of the inner support frame 19 is a rear connecting ring 13, which is fitted onto the inner guide rod 1 and fixedly connected to the middle guide tube 2. When the support frame 5 is in the expanded working state, the middle section of the inner support frame 19 is radially away from the inner guide rod 1. When the support frame 5 is in the contracted working state, the inner support frame 19... The middle section of the inner support frame 19 is radially close to the inner guide rod 1. Multiple outer support rods 20, parallel to the inner guide rod 1, are fixedly connected to the middle section of the inner support frame 19. These outer support rods 20 are distributed in a cylindrical, spaced-apart pattern around the inner support frame 19. Each outer support rod 20 has a forward extension section 21 extending forward of the middle section of the inner support frame 19, and / or a rear extension section 22 extending backward of the middle section of the inner support frame 19, such that the length of the outer support rod 20 in the front-rear direction is greater than the length of the middle section of the inner support frame 19 in the front-rear direction. In some variant structures, the length of the electrode film 6 in the front-rear direction is greater than or equal to the length of the outer support rod 20 in the front-rear direction; optionally, the length difference between the two is less than 30 mm, preferably less than 2 mm. In some variant structures, there are 5-12 outer support rods 20. The outer support rod 20 supports the electrode membrane 6. The length of the outer support rod 20 in the front-back direction is greater than the length of the middle section of the inner support frame 19 in the front-back direction. This can greatly shorten the length of the middle section of the inner support frame 19 in the front-back direction. Compared with the prior art where the electrode membrane 6 is directly connected to the middle section of the inner support frame 19, the length of the support frame 5 in the front-back direction in the contracted state of this embodiment is smaller.

[0355] Because the contractile support frame 5 is a rigid component in the radial direction and cannot be bent radially, while other components, such as the anterior guide cap 29 and the posterior guide cap 32, are made of rubber or silicone, which are soft and easily bendable, and the inner guide rod 1, the middle guide tube 2, and the outer guide tube 3 are slender components that can be bent radially to a suitable extent, the shorter the length of the support frame 5 in the anterior-posterior direction, the easier it is to pass through the curved digestive tract without damaging the inner wall of the digestive tract. With the electrode membrane 6 of the same length in the anterior-posterior direction, the setting of the outer support rod 20 makes the support frame 5 shorter in the anterior-posterior direction in the contractile working state compared to the expansion working state, thus greatly shortening the length of the contracted support frame 5 in the anterior-posterior direction, making it easier to pass through the curved digestive tract.

[0356] In some variant structures, such as Figure 4 As shown, when the support frame 5 is in the expanded working state, the length of the outer support rod 20 in the front-to-back direction is greater than or equal to the length of the inner support frame 19 in the front-to-back direction. Figure 4The two are of equal length), and the front end of the inner support frame 19 is located behind or aligned with the front end of the outer support rod 20, and the rear end of the inner support frame 19 is located in front of or aligned with the rear end of the outer support rod 20. Figure 4 (For alignment). The inner end 8 of the electrode membrane is connected to an outer support rod 20. In some variations, when the support frame 5 is in the retracted working state, the length of the outer support rod 20 in the front-rear direction is greater than or equal to the length of the inner support frame 19 in the front-rear direction (not shown).

[0357] An alternative variation is that the internal support frame 19 includes multiple internal support rods 24, see Figure 4 When the support frame 5 is in its expanded working state, the inner support rod 24 is arc-shaped with its opening facing the inner guide rod 1. Each outer support rod 20 is fixedly connected to the middle section of the inner support rod 24, and the length of the outer support rod 20 is 1.5 to 12 times the length of the middle section of the inner support rod 24. See Figure 2 When the support frame 5 is in its retracted state, the inner support rod 24 is approximately straight. The inner support frame 19 is made of shape memory alloy, and when the support frame 5 is in its expanded state, the shape of the inner support frame 19 is the preset shape of the shape memory alloy. In some modified structures, when the length of the outer support rod 20 is much greater than the length of the middle section of the inner support rod 24, the length of the outer support rod 20 in the front-rear direction is also greater than the length of the inner support rod 24 in the front-rear direction when the support frame 5 is in its retracted state.

[0358] In some variations of Embodiment 1 of the support frame 5, for example, the front middle portion and / or the rear middle portion of the inner support rod 24 are pivotally connected to the front connecting ring 12 or the rear connecting ring 13, respectively, with the pivot perpendicular to the inner guide rod 1.

[0359] See Figure 14The second embodiment of the support frame 5 is as follows: it includes an inner support frame 19, a middle support frame 23, and multiple outer support rods 20 parallel to the inner guide rod 1. The front end of the inner support frame 19 is a front connecting ring 12 (i.e., the inner support frame 19 is fixedly connected to the front connecting ring 12 or integrally formed), and the front connecting ring 12 can be slidably sleeved on the inner guide rod 1 in the front-back direction; the rear end of the inner support frame 19 is a rear connecting ring 13 (i.e., the inner support frame 19 is fixedly connected to the rear connecting ring 13 or integrally formed), and the rear connecting ring 13 is sleeved on the inner guide rod 1 and fixedly connected to the middle guide rod 2; when the support frame 5 is in the expanded working state, the middle section of the inner support frame 19 is radially away from the inner guide rod 1, and when the support frame 5 is in the contracted working state, the middle section of the inner support frame 19 is radially close to the inner guide rod 1. The middle section of the inner support frame 19 is fixedly connected to the middle support frame 23, which has two ends: a front end and a rear end. One of these ends is fixedly or pivotally connected to the outer support rod 20. Figure 14 The middle end is fixedly connected to the outer support rod 20 at the rear end, and the other end of the two ends is slidably connected to the outer support rod 20 in the front-back direction. Figure 14 The central support frame 23 has a front end that is slidably connected to the outer support rod 20 in the front-back direction via a sliding groove 33. Multiple outer support rods 20 are distributed in a cylindrical shape around the central support frame 23. In some modified structures, both ends are slidably connected to the outer support rods 20 in the front-back direction. In this case, when the support frame 5 expands or contracts, the electrode membrane 6 will not move in the front-back direction, which facilitates accurate positioning of the target tissue.

[0360] Regardless of whether the support frame 5 is in a contracted or expanded working state, the length of the outer support rod 20 in the front-to-back direction is greater than or equal to the length of the middle support frame 23 in the front-to-back direction.

[0361] In some variations, regardless of whether the support frame 5 is in a retracted or expanded working state, the outer support rod 20 has a front extension section 21 extending forward toward the front end of the central support frame 23, or / and the outer support rod 20 has a rear extension section 22 extending backward toward the rear end of the central support frame 23, such that the length of the outer support rod 20 in the front-rear direction is greater than the length of the central support frame 23 in the front-rear direction (not shown).

[0362] In some modified structures, regardless of whether the support frame 5 is in a contracted or expanded working state, the length of the outer support rod 20 in the front-to-back direction is greater than or equal to the length of the middle support frame 23 in the front-to-back direction, and the front end of the middle support frame 23 is located behind or aligned with the front end of the outer support rod 20, and the rear end of the middle support frame 23 is located in front of or aligned with the rear end of the outer support rod 20.

[0363] In some modified structures, regardless of whether the support frame 5 is in a contracted or expanded working state, the length of the outer support rod 20 in the front-to-back direction is greater than or equal to the length of the inner support frame 19 in the front-to-back direction, and the front end of the inner support frame 19 is located behind or aligned with the front end of the outer support rod 20, and the rear end of the inner support frame 19 is located in front of or aligned with the rear end of the outer support rod 20.

[0364] In some modified structures, regardless of whether the support frame 5 is in a contracted or expanded working state, the length of the middle support frame 23 in the front-to-back direction is greater than or equal to the length of the inner support frame 19 in the front-to-back direction, and the front end of the inner support frame 19 is located behind or aligned with the front end of the middle support frame 23, and the rear end of the inner support frame 19 is located in front of or aligned with the rear end of the middle support frame 23.

[0365] In the second embodiment of the support frame 5, the inner support frame 19 and the middle support frame 23 are connected in two stages. In this second embodiment of the support frame 5, the length of the outer support rod 20 in the front-back direction is the maximum length of the support frame 5 in the front-back direction, which makes it easier for the support frame 5 of this embodiment to pass through the digestive tract in the contracted state.

[0366] In some variant structures, see Figure 14 The inner support frame 19 includes multiple inner support rods 24. When the support frame 5 is in the expanded working state, the inner support rods 24 are in an arc shape with their openings facing the inner guide rod 1. The middle support frame 23 includes multiple middle support rods 25. When the support frame 5 is in the expanded working state, the middle support rods 25 are in an arc shape with their openings facing away from the inner guide rod 1. The middle sections of each middle support rod 25 are fixedly connected to the middle sections of each inner support rod 24. When the support frame 5 is in the contracted working state, the middle support rods 25 and the inner support rods 24 are in a generally straight line shape.

[0367] In some variations of Embodiment 2 of the support frame 5, for example, the front end and / or the rear end of the inner support rod 24 are pivotally connected to the front connecting ring 12 or the rear connecting ring 13, respectively, with the pivot perpendicular to the inner guide rod 1.

[0368] In the support frame 5 of Embodiment 1 and Embodiment 2, the middle section of the inner support rod 24 refers to the part of the inner support rod that is basically parallel to the inner guide rod 1 when the support frame 5 is in the expanded working state, and the middle section of the middle support rod 25 refers to the part of the middle support rod that is basically parallel to the inner guide rod 1 when the support frame 5 is in the expanded working state.

[0369] See Figure 14 and Figure 24In some modified structures, the middle support rod 25 has a front end 26 and a rear end 27. One end is fixedly or pivotally connected to the outer support rod 20, and the other end is slidably connected to the outer support rod 20 in the front-rear direction via a sliding groove 33. In some modified structures, both ends are slidably connected to the outer support rod 20 in the front-rear direction via sliding grooves 33.

[0370] In some variant structures, the outer support rod 20 has a front extension 21 extending forward toward the front end 26 of the middle support rod, and / or the outer support rod 20 has a rear extension 22 extending backward toward the rear end 27 of the middle support rod, such that the length of the outer support rod 20 in the front-rear direction is greater than the length of the middle support rod 25 in the front-rear direction (not shown).

[0371] In some modified structures, the length of the electrode film 6 in the front-back direction is greater than or equal to the length of the outer support rod 20 in the front-back direction. Optionally, the length difference between the two is less than 30 mm, preferably less than 2 mm. Optionally, there are 5-12 outer support rods 20.

[0372] In some modified structures, when the support frame 5 is in an expanded working state, the length of the outer support rod 20 in the front-rear direction is greater than or equal to the length of the inner support frame 19 in the front-rear direction, and the front end of the inner support frame 19 is located behind or aligned with the front end of the outer support rod 20, and the rear end of the inner support frame 19 is located in front of or aligned with the rear end of the outer support rod 20. The inner end portion 8 of the electrode film is connected to the outer support rod 20.

[0373] See Figures 22-1 to 22-3 A modified structure of the support frame in Embodiment 1, wherein the front middle part of the support frame 5 is rotatably connected to a front connecting ring 12 via a pivot 18, and the rear middle part of the support frame 5 is rotatably connected to a rear connecting ring 13 via a pivot 18. Figures 22-1 to 22-3 In the inner support frame 19, multiple inner support rods 24 are included. The front end of each inner support rod 24 is rotatably connected to the front connecting ring 12 via a pivot 18, and the rear end of each inner support rod 24 is rotatably connected to the rear connecting ring 13 via a pivot 18. Each pivot 18 is spatially perpendicular to the inner guide rod 1 or the middle guide tube 2. The inner support rods 24 and the outer support rods 20 are fixedly connected by rivets 36.

[0374] Similarly, Figure 14The second embodiment of the support frame shown can also have a variant structure (not shown). Referring to the variant structure of the first embodiment of the support frame described above, the front middle portion of the support frame 5 is rotatably connected to a front connecting ring 12 via a pivot 18, and the rear middle portion of the support frame 5 is rotatably connected to a rear connecting ring 13 via a pivot 18. Specifically, the inner support frame 19 includes multiple inner support rods 24. The front portion of each inner support rod 24 constitutes the front middle portion of the support frame 5 in this embodiment, and the rear portion of each inner support rod 24 constitutes the rear middle portion of the support frame 5 in this embodiment. The front ends of each inner support rod 24 are rotatably connected to the front connecting ring 12 via pivots 18, and the rear ends of each inner support rod 24 are rotatably connected to the rear connecting ring 13 via pivots 18. Each pivot 18 is spatially perpendicular to the inner guide rod 1 or the middle guide tube 2.

[0375] The inner support frame 19 and the middle support frame 23 are made of shape memory alloy materials (such as nickel-titanium alloy), stainless steel, certain hard plastics with good elasticity and non-toxic to the human body, etc. When the support frame 5 is in the expanded working state, the shape of the inner support frame 19 and the middle support frame 23 is the preset shape of the shape memory alloy, so that the inner support frame 19 can tend to return to the expanded working state when it is in the contracted working state.

[0376] In some variant structures, such as Figure 18 When the support frame 5 is in the retracted working state, the electrode film 6 is wound in multiple turns around the support frame 5; as Figure 17 When the supporting frame 5 is in the expanded working state, the number of turns of the electrode film 6 is greater than 1 turn and less than 2 turns.

[0377] In some variant structures, such as Figure 1 and 2 As shown, the front end of the inner guide rod 1 is fixedly connected to the front guide cap 29. The inner guide rod 1 is a tubular body with a guidewire lumen 30. The front guide cap 29 also has a guidewire lumen 30 in its center, which is connected to the guidewire lumen 30 of the inner guide rod 1. During the ablation procedure, a guidewire passes through the guidewire lumen 30. After the ablation device is inserted into the digestive tract at the target location, during the transition of the expandable component 4 from the contraction state to the expansion state, only the support frame 5 rotates under the drive of the middle catheter 2. The inner guide rod 1, the outer catheter 3, and the front guide cap 29 do not rotate, thus preventing damage to the inner wall of the digestive tract. After the ablation of the target tissue is completed, during the transition of the expandable component 4 from the expansion state to the contraction state, the outer catheter 3, the inner guide rod 1, and the front guide cap 29 do not rotate. The support frame 5 only rotates within the electrode membrane 6, again preventing damage to the inner wall of the digestive tract.

[0378] See Figure 4 , Figure 11In some variations, the support frame 5 includes an inner support frame 19 and multiple outer support rods 20 connected to the inner support frame 19. The outer support rods 20 are parallel to the middle guide tube 2 and also parallel to the inner guide rod 1. The multiple outer support rods 20 are distributed in a cylindrical shape around the inner support frame 19. The inner end 8 of the electrode film is connected to one of the outer support rods 20.

[0379] In some variations, the support frame 5 is made of elastic nickel-titanium alloy, elastic stainless steel, elastic plastic, etc.

[0380] exist Figure 14 In the support frame 5, the inner support frame 19 and the middle support frame 23 are made of nickel-titanium alloy, elastic stainless steel, elastic plastic, etc.

[0381] The selection requirements for the support frame 5 are as follows: when the front end of the support frame 5 is far away from or close to the rear end of the support frame 5, the support frame 5 is in a contracted working state or an expanded working state. That is, the outermost middle member of the support frame 5 is close to or far away from the inner guide rod 1, and the outermost middle member of the support frame 5 is distributed in a cylindrical interval around the inner guide rod 1. When the support frame 5 changes between the contracted working state and the expanded working state, the shape of some individual members on the support frame 5 will change. These individual members have elastic force when compressed, and the elastic force makes the support frame 5 tend to change from the contracted working state to the expanded working state. In the contracted working state, these elastic members are compressed by the radial contraction force of the electrode film 6. When the electrode film 6 expands, the elastic force makes the support frame 5 enter the expanded working state. This disclosure only exemplifies a part of the support frame 5. The support frame referred to in this disclosure is not limited to the illustrated embodiment. Under the premise of meeting the above selection requirements, other unexemplified support frames based on the concept of this disclosure also belong to the support frame referred to in this disclosure.

[0382] See Figures 30 to 36-2 This embodiment provides another device for ablation treatment of the digestive tract, which includes: 2. Slender middle duct; A slender outer conduit 3 is sleeved on the middle conduit 2, and the middle conduit 2 is rotatably disposed relative to the outer conduit 3; An expandable component 4 surrounds the central conduit 2. The expandable component 4 includes a support frame 5 and a flexible electrode membrane 6. The expandable component 4 has a radially decreasing contraction working state and a radially increasing expansion working state. The support frame 5 is connected to the central conduit 2. The deformable part of the support frame 5 when changing between the contraction and expansion working states is made of a rigid elastic material. The rigid elastic material gives the support frame 5 a radially outward elastic force when changing from the contraction working state to the expansion working state. The electrode membrane 6 is provided with multiple electrodes 7 for receiving electrical signals, including signals for heating target tissue, electric field ablation, radio frequency signals, etc., which can be pulse signals. The electrode membrane 6 is spirally wound on the support frame 5. The inner end 8 of the electrode membrane is connected to the support frame 5, and the outer end 9 of the electrode membrane is connected to the outer conduit 3 through a connector. One option is that the actuator is an operating handle 28, the structure of which is described in [reference needed]. Figure 34 (Refer to its radial section diagram) Figure 21 It's just a matter of putting Figure 21 The inner guide rod 1 is replaced by a middle guide tube 2. The outer guide tube 3 is fixedly connected to the operating handle body 35. The middle guide tube 2 is fixedly connected to the internal gear 10, which is a rotating component. The knob 34 is rotatably mounted on the operating handle body 35 and drives the internal gear 10 to rotate via the intermediate gear 11, thereby causing the middle guide tube 2 to rotate relative to the outer guide tube 3. The knob 34 is restricted to rotating only relative to the operating handle body 35 and cannot move in the back-and-forth direction relative to the operating handle body 35. In some variant structures, the middle guide tube 2 can also be directly fixed to the knob 34. When the knob 34 is turned, the middle guide tube 2 is driven to rotate, so that the middle guide tube 2 rotates in the forward direction relative to the outer guide tube 3, and the support frame 5 also rotates in the forward direction relative to the outer guide tube 3. The inner end 8 of the electrode membrane is also driven to rotate in the forward direction. At the same time, the electrode membrane 6 expands radially, and the support frame 5 also expands radially under the action of the rigid elastic material. The actuator is also used to drive the middle guide tube 2, so that the middle guide tube 2 rotates in the opposite direction relative to the outer guide tube 3. At the same time, the electrode membrane 6 contracts radially, and the electrode membrane 6 compresses and tightens the support frame 5 to contract radially.

[0383] Another option is that, during the transition of the expandable component 4 from a contracted to an expanded state, the actuator drives the connected outer conduit 3 to rotate in the opposite direction relative to the middle conduit 2, causing the electrode membrane 6 to expand radially while the supporting frame 5 also expands radially under the action of the rigid elastic material; during the transition of the expandable component 4 from an expanded to a contracted state, the actuator drives the connected outer conduit 3 to rotate in the forward direction relative to the middle conduit 2, causing the electrode membrane 6 to contract radially while simultaneously compressing the supporting frame 5 to contract radially. Specifically, ... Figure 34The structure of the operating handle 28 is modified as follows: the knob 34 is rotatably mounted in the middle of the operating handle body 35. The knob 34 is clamped on the operating handle body 35 and can only rotate relative to the operating handle body 35, not move back and forth relative to the operating handle body 35. The rear of the outer conduit 3 is fixedly connected to the internal gear 10, which is a rotating component, and the middle conduit 2 is fixedly connected to the rear of the operating handle body 35. In some variant structures, the outer conduit 3 can also be directly fixed to the knob 34. The actuator is used to drive the outer conduit 3, causing the outer conduit 3 to rotate in the opposite direction relative to the middle conduit 2. While the electrode membrane 6 expands radially, the support frame 5 also expands radially under the action of the rigid elastic material. The actuator is also used to drive the outer conduit 3, causing the outer conduit 3 to rotate in the forward direction relative to the middle conduit 2. While the electrode membrane 6 contracts radially, the electrode membrane 6 compresses and tightens the support frame 5, causing it to contract radially.

[0384] In some variant structures, see Figure 35-1 , Figure 35-2 The device for ablation therapy of the digestive tract also includes an inner guide rod 1, a middle catheter 2 sleeved on the inner guide rod 1, and the middle catheter 2 rotatably disposed relative to the inner guide rod 1. The inner guide rod 1 is fixedly disposed to the outer catheter 3. A front guide cap 29 is fixedly connected to the front end of the inner guide rod 1. The inner guide rod 1 is a tubular body with a guidewire lumen 30. The center of the front guide cap 29 also has a guidewire lumen 30 and communicates with the guidewire lumen 30 of the inner guide rod 1. The operating handle for the actuator to drive the rotation of the middle catheter 2 relative to the outer catheter 3 can be found in [reference needed]. Figure 9 and Figure 21 Its working principle has been described above. Primarily, the internal gear 10, acting as a rotating component, is driven to rotate by the knob 34, which in turn causes the middle guide tube 2 to rotate relative to the inner guide rod 1 or the outer guide tube 3. The operating handle 28, which serves as the actuator, can also be found in [reference needed]. Figure 25 Its working principle has been described above. Knob 34 drives the middle guide tube 2 and the outer guide tube 3 to rotate in opposite directions relative to the inner guide rod 1.

[0385] See Figure 35-1 and Figure 35-2 The support frame 5 includes an inner support rod 24 and an outer support rod 20. The middle part of the inner support rod 24 is fixedly connected to the central guide tube 2. Both the front and rear ends of the inner support rod 24 are slidably connected to the outer support rod 20 via sliding grooves 33 on the outer support rod 20 in a front-rear direction (another structure not shown is where one end is slidably connected to the outer support rod 20 via the sliding grooves 33 in a front-rear direction, and the other end is fixed or pivotally connected to the outer support rod 20). When the support frame 5 is in the expanded working state, the inner support rod 24 is in an arc shape with its opening facing outwards; see [reference missing]. Figure 35-2When the support frame 5 is in the contracted working state, the inner support rod 24 is compressed into a roughly straight shape by the electrode membrane 6. The structure of this support frame 5 ensures that regardless of whether the expandable component 4 is in the expanded or contracted working state, the outer support rod 20, as the longest rod in the front-back direction of the support frame 5, matches the electrode membrane 6. When the support frame 5 is in the contracted state, its shorter length makes it easier to pass through the curved digestive tract.

[0386] In some variant structures, see Figure 36-1 The support frame 5 includes an annular rod 50 and an outer support rod 20. The inner side of the annular rod 50 is fixedly connected to the middle guide tube 2, and the outer side of the annular rod 50 is fixedly connected to the outer support rod 20. When the support frame 5 is in the expanded working state, the annular rod is an open annular shape; when the support frame 5 is in the contracted working state, the annular rod is a flattened, roughly straight shape (see...). Figure 36-1 The structure of this support frame 5 ensures that, regardless of whether the expandable component 4 is in an expanded or contracted state, the outer support rod 20, as the longest member of the support frame 5 in the longitudinal direction, matches the electrode membrane 6. Therefore, when the support frame 5 is in the contracted state, its shorter length allows for easier passage through the curved digestive tract. Furthermore, when the support frame 5 transitions from a contracted to an expanded state, the outer support rod 20 and the electrode membrane 6 only move radially, without any longitudinal movement, facilitating accurate positioning and ablation of the target tissue by the physician.

[0387] In an embodiment of an ablation treatment device for the digestive tract including an inner guide rod 1, a middle catheter 2, and an outer catheter 3, the connector includes an outer end rod 14 and a connecting strip 15 that is rigid in the circumferential direction. The outer end rod 14 is parallel to the inner guide rod 1 and connected to the outer end 9 of the electrode membrane. One end of the connecting strip 15 is connected to the outer end rod 14, and the other end of the connecting strip 15 is connected to the outer catheter 3 and / or the inner guide rod 1. During the transition of the support frame 5 from a contracted working state to an expanded working state, the outer end rod 14 gradually moves away from the inner guide rod 1, and during the transition of the support frame 5 from an expanded working state to a contracted working state, the outer end rod 14 gradually moves closer to the inner guide rod 1.

[0388] The connecting strip 15 and the outer end rod 14 are selected from the following three connection structures: pivot connection, fixed connection, and slidable connection in the front-back direction, wherein the pivot of the pivot connection is perpendicular to the inner guide rod 1; the connecting strip 15 and the outer guide tube 3 and / or the inner guide rod 1 are selected from the following three connection structures: pivot connection, fixed connection, and slidable connection in the front-back direction, wherein the pivot of the pivot connection is perpendicular to the inner guide rod 1.

[0389] In some variations, the distance between the front and rear ends of the connecting strip 15 can be variably set. For example, see... Figure 29-2The connecting strip 15 is a rigid, flexible sheet that is radially elastic and can be bent. When the supporting frame 5 is in the retracted working state, the connecting strip 15 is bent. For example, see Figure 22-4 The connecting bar 15 includes multiple sections 17. The ends of two adjacent sections 17 are pivotally connected to form a chain. The inner guide rod 1 is slidably connected to an adjacent section 17 in the front-back direction but is prohibited from rotating through the first axial rib 46. The outer end rod 14 is pivotally connected to an adjacent section 17. The axis of each pivot is perpendicular to the inner guide rod 1 in space.

[0390] In some variations, see Figure 27 The connecting bar 15 includes multiple sections 17, with the ends of two adjacent sections 17 pivotally connected to form a chain. The outer guide tube 3 is pivotally connected to an adjacent section 17, and the outer end rod 14 is pivotally connected to an adjacent section 17. The axis of each pivot is perpendicular to the inner guide rod 1 in space.

[0391] In some variations, see Figure 29-3 The connecting bar 15 includes multiple sections of rod 17, which are slidably connected to form a telescopic rod. The outer end rod 14 is pivotally connected to the end of an adjacent section of rod 17. The outer guide tube 3 (or / and the inner guide rod 1) is pivotally connected to an adjacent section of rod 17. The axis of each pivot is perpendicular to the inner guide rod 1 in space.

[0392] In some variations, see Figure 29-1 The connecting strip 15 includes a connecting strip 15 located at the front of the outer end rod 14 and a connecting strip 15 located at the rear of the outer end rod 14; the rear end of the connecting strip 15 located at the front of the outer end rod 14 is connected to the front end of the outer end rod 14, and the front end of the connecting strip 15 located at the front of the outer end rod 14 is connected to the inner guide rod 1; the front end of the connecting strip 15 located at the rear of the outer end rod 14 is connected to the rear end of the outer end rod 14, and the rear end of the connecting strip 15 located at the rear of the outer end rod 14 is connected to the outer guide tube 3.

[0393] Some variant structures do not have inner guide rod 1, see Figure 30 and Figure 31 The support frame 5 has a front end (i.e., front connecting ring 12) and a rear end (i.e., rear connecting ring 13). The front end of the support frame 5 is sleeved on the middle guide tube 2. This end is a movable end relative to the middle guide tube 2 in the front-back direction and the circumferential direction. That is, the front end of the support frame 5 is movably set relative to the middle guide tube 2 in the front-back direction and the circumferential direction. The rear end of the support frame 5 is fixedly connected to the middle guide tube 2.

[0394] Some variant structures do not have inner guide rod 1, see Figure 32 and Figure 33The support frame 5 has two ends: a front end (i.e., the front connecting ring 12) and a rear end (i.e., the rear connecting ring 13). Both ends of the support frame 5 are fitted onto the middle guide tube 2, and both ends are slidably connected to the middle guide tube 2 in the front-rear direction, while both ends are non-rotatably connected to the middle guide tube 2. Specifically, the middle guide tube 2 has a second axial rib 47, which extends in the front-rear direction and protrudes radially. The inner walls of the front connecting ring 12 and the rear connecting ring 13 both have radially recessed guide grooves, and the second axial rib 47 is inserted into the guide grooves. The middle guide tube 2 at the front of the front connecting ring 12 has a radially outwardly protruding front limit block 48, and the middle guide tube 2 at the rear of the rear connecting ring 13 has a radially outwardly protruding rear limit block 49. The front limit block 48 and the rear limit block 49 are used to limit the front limit position or the rear limit position of the support frame 5 relative to the middle guide tube 2 in the front-rear direction, respectively.

[0395] In some variant structures, the inner guide rod 1 is not shown. The support frame 5 has two ends: the front end (i.e., the front connecting ring 12) and the rear end (i.e., the rear connecting ring 13). Both ends of the support frame 5 are sleeved on the middle guide tube 2. One end is slidably set with the middle guide tube 2 in the front-back direction and is not rotatably connected to the middle guide tube 2. The other end is a movable end that allows rotation in the circumferential direction and sliding in the front-back direction. That is, the other end is rotatable in the circumferential direction and slidable in the front-back direction relative to the middle guide tube 2.

[0396] In some variant structures, the support frame 5 has a front end and a rear end. The rear end of the support frame is connected to the central conduit 2. The connection includes the three connection methods mentioned above, except for the third connection method. However, the pivot of the first connection method needs to be perpendicular to the central conduit 2. The front end of the support frame is suspended (not shown).

[0397] In some variant structures, see Figures 30 to 36-2 The connector includes an outer end rod 14 connected to the outer end of the electrode membrane and a connecting strip 15. One end of the connecting strip 15 is connected to the outer end rod 14, and the other end of the connecting strip 15 is connected to the outer conduit 3. When the support frame 5 changes between the contraction and expansion working states, the distance between the front and rear ends of the connecting strip 15 is variable, and the connecting strip 15 is rigid in the circumferential direction. During the process of the support frame 5 changing from the contraction working state to the expansion working state, the outer end rod 14 gradually moves away from the middle conduit 2. During the process of the support frame 5 changing from the expansion working state to the contraction working state, the outer end rod 14 gradually moves closer to the middle conduit 2. The outer end rod 14 is parallel to the middle conduit 2.

[0398] In some variant structures, see Figure 29-2The connecting strip 15 is a rigid elastic sheet that can be bent. When the supporting frame 5 is in the contracted working state, the rigid elastic sheet is bent (not shown).

[0399] In some variant structures, see Figure 31 The connecting bar 15 includes multiple sections 17, with the ends of two adjacent sections 17 pivotally connected to form a chain. The outer conduit 3 is pivotally connected to an adjacent section 17, and the outer end rod 14 is pivotally connected to an adjacent section 17. The axis of each pivot is perpendicular to the middle conduit 2 in space.

[0400] In some variant structures (see) Figure 29-3 The connecting bar 15 includes multiple sections 17, at least two sections 17 are slidably connected by a groove, the outer end bar 14 is pivotally connected to the end of an adjacent section 17, the outer conduit 3 is pivotally connected to an adjacent section 17, and the axis of each pivot is spatially perpendicular to the middle conduit 2.

[0401] In some variant structures, see Figures 30 to 36-2 The support frame 5 includes an inner support frame 19 and multiple outer support rods 20 connected to the inner support frame 19. The outer support rods 20 are parallel to the middle guide tube 2. The multiple outer support rods 20 are distributed in a cylindrical shape with equal intervals around the inner support frame 19. The inner end 8 of the electrode film is connected to one of the outer support rods 20.

[0402] In some modified structures, the length of the electrode film 6 in the front-to-back direction is greater than or equal to the length of the outer support rod 20 in the front-to-back direction, and the length difference between the two is less than 30 mm, preferably less than 2 mm. The support frame 5 is made of elastic nickel-titanium alloy material, elastic stainless steel material, elastic plastic, etc.

[0403] See Figure 18 When the support frame 5 is in the retracted working state, the electrode film 6 is wound in multiple turns around the support frame 5; see also Figure 17 When the supporting frame 5 is in the expanded working state, the number of turns of the electrode film 6 is greater than 1 turn and less than 2 turns.

[0404] See the figures, except Figure 35-1 , Figure 35-2 , Figure 36-1 , Figure 36-2 Except for the support frame 5 in the figures, the support frames 5 in the other figures are in a contracted working state when the front end of the support frame is far away from the rear end of the support frame, and in an expanded working state when the front end of the support frame is close to the rear end of the support frame.

[0405] Figures 1 to 37-22In the embodiments shown, the support frame 5 has a radially outward elastic force when it contracts, which causes the electrode film 6 to clamp the support frame 5. The innermost ring of the electrode film 6 is always in close contact with the support frame 5, and the electrode films 6 of each adjacent ring are also always in close contact with each other.

[0406] See Figures 30 to 33 The first embodiment of the support frame 5 includes an inner support frame 19 and multiple outer support rods 20. The front end of the inner support frame 19 is a front connecting ring 12, and the rear end of the inner support frame 19 is a rear connecting ring 13. Multiple outer support rods 20 parallel to the central guide tube 2 are fixedly connected to the middle section of the inner support frame 19. The multiple outer support rods 20 are distributed in a cylindrical interval (preferably at equal intervals) around the inner support frame 19. The outer support rods 20 have a front extension section 21 extending forward of the middle section of the inner support frame 19, and / or a rear extension section 22 extending backward of the middle section of the inner support frame 19, such that the length of the outer support rods 20 in the front-back direction is greater than the length of the middle section of the inner support frame 19 in the front-back direction. The inner support frame 19 is made of a nickel-titanium alloy, an elastic stainless steel, an elastic plastic, or the like.

[0407] Specifically, the inner support frame 19 includes multiple inner support rods 24. When the support frame 5 is in the expanded working state, the inner support rods 24 are in the shape of an inward-facing bow. Each outer support rod 20 is fixedly connected to the middle section of the inner support rod 24. When the support frame 5 is in the contracted working state, the inner support rods 24 are in a roughly straight shape. When the support frame 5 is in the expanded working state, the length of the outer support rods 20 in the front-back direction is greater than or equal to the length of the inner support frame 19 in the front-back direction. Furthermore, the front end of the inner support frame 19 is located behind or aligned with the front end of the outer support rods 20, and the rear end of the inner support frame 19 is located in front of or aligned with the rear end of the outer support rods 20.

[0408] Some variations of the support frame 5 in Embodiment 1 include: the front end of the support rod 24 and / or the rear end of the inner support rod are pivotally connected to the front connecting ring 12 or the rear connecting ring 13, respectively, with the pivot perpendicular to the inner guide rod 1.

[0409] See Figure 14Embodiment 2 of the support frame 5 includes an inner support frame 19, a middle support frame 23, and multiple outer support rods 20 parallel to the inner guide rod 1 or the middle guide tube 2. The front end of the inner support frame 19 is a front connecting ring 12, and the rear end of the inner support frame 19 is a rear connecting ring 13. The middle section of the middle support frame 23 is fixedly connected to the middle section of the inner support frame 19. The middle support frame 23 has a front end and a rear end. One end of the two ends is fixedly or pivotally connected to the outer support rod 20, and the other end of the two ends is slidably connected to the outer support rod 20 in the front-back direction. The multiple outer support rods 20 are distributed in a cylindrical space (preferably at equal intervals) around the middle support frame 23. The length of the outer support rods 20 in the front-back direction is greater than or equal to the length of the middle support frame 23 in the front-back direction.

[0410] refer to Figure 24 Specifically, the inner support frame 19 includes multiple inner support rods 24, and the middle support frame 23 includes multiple middle support rods 25. When the support frame is in its expanded working state, the inner support rods 24 are in an inward-facing arc shape, and the middle support rods 25 are in an outward-facing arc shape. The middle section of each middle support rod 25 is fixedly connected to the middle section of the inner support rod 24. In this embodiment, the middle section of each middle support rod 25 is fixedly connected to the middle section of the inner support rod 24 by rivets 36. When the support frame 5 is in its contracted working state, both the middle support rods 25 and the inner support rods 24 are generally straight. The middle support rod 25 has a front end 26 and a rear end 27. One end of the two ends is fixedly or pivotally connected to the outer support rod 20, and the other end of the two ends is slidably connected to the outer support rod 20 in the front-rear direction. The outer support rod 20 has a front extension section 21 extending forward of the front end 26 of the middle support rod, and / or a rear extension section 22 extending backward of the rear end 27 of the middle support rod, such that the length of the outer support rod 20 in the front-rear direction is greater than the length of the middle support rod 25 in the front-rear direction. The inner support frame 19 and the middle support frame 23 are made of nickel-titanium alloy, elastic stainless steel, elastic plastic, etc. The length of the outer support rod 20 in the front-rear direction is greater than or equal to the length of the middle support frame 23 in the front-rear direction, and the front end of the middle support frame 23 is located behind or aligned with the front end of the outer support rod 20, and the rear end of the middle support frame 23 is located in front of or aligned with the rear end of the outer support rod 20; the length of the outer support rod 20 in the front-rear direction is also greater than or equal to the length of the inner support frame 19 in the front-rear direction, and the front end of the inner support frame 19 is located behind or aligned with the front end of the outer support rod 20, and the rear end of the inner support frame 19 is located in front of or aligned with the rear end of the outer support rod 20.

[0411] In some variations of Embodiment 2 of the support frame 5, for example, the front end and / or rear end of the inner support rod 24 are pivotally connected to the front connecting ring 12 or the rear connecting ring 13, respectively, with the pivot perpendicular to the inner guide rod 1.

[0412] The distance between the front and rear ends of the support frame 5 can vary relative to each other, causing the support frame 5 to switch between a contracted and expanded state. The selection of this support frame 5 requires that when the front end of the support frame 5 is farther or closer to the rear end relative to the rear end, the support frame 5 is in a contracted or expanded working state. That is, the outermost middle member of the support frame 5 is closer to or farther from the inner guide rod 1, and the outermost middle members of the support frame 5 are distributed in a cylindrical interval (preferably equally spaced) around the inner guide rod 1. When the support frame 5 switches between the contracted and expanded working states, the shape of some individual members on the support frame 5 will change. These individual members have elastic force when compressed, and the elastic force causes the support frame 5 to tend to change from a contracted working state to an expanded working state. In the contracted working state, these elastic members are compressed by the radial contraction force of the electrode film 6. When the electrode film 6 expands, the elastic force causes the support frame 5 to enter the expanded working state. This disclosure only illustrates a portion of the support frame 5. The support frame referred to in this disclosure is not limited to the illustrated embodiments. Provided that the above selection requirements are met, other unillustrated support frames based on the concept of this disclosure also belong to the support frames referred to in this disclosure.

[0413] The following combination Figures 37-1 to 37-22 Another embodiment of the support frame and the corresponding apparatus for ablation treatment of the digestive tract will be described. The main difference from the aforementioned other embodiments lies in the specific structure of the support frame.

[0414] The support frame 5 in this embodiment also has a radially shrinking contraction working state and a radially expanding expansion working state. The support frame 5 includes multiple outer support rods 20 and an inner support frame connected to the outer support rods 20. The inner support frame includes multiple first connecting rods 52, multiple second connecting rods 53, a front connecting ring 12 located at the front, and a rear connecting ring 13 located at the rear. The multiple linkage mechanisms of the support frame include at least one X-type linkage mechanism. In the X-type linkage mechanism, the rear end 52b of the first connecting rod 52 is fixedly connected to the rear of the outer support rod 20, the front end 52a of the first connecting rod 52 is fixedly connected to the front connecting ring 12 (or integrally formed), the front end 53a of the second connecting rod 53 is fixedly connected to the front of the outer support rod 20, and the rear end 53b of the second connecting rod 53 is fixedly connected to the rear connecting ring 13 (or integrally formed). The first link 52 and the second link 53 intersect in an X shape. In some embodiments, the intersection of the first link 52 and the second link 53 is not connected, while in other embodiments, a mutually cooperating groove and pin limiting mechanism can be provided at the intersection of the first link 52 and the second link 53. This is not limited here.

[0415] In some embodiments, at least one of the front portion of the first link 52, the rear portion of the first link 52, the front portion of the second link 53, and the rear portion of the second link 53 constitutes or is provided with the deformable component. In this embodiment, all four portions of the first link 52, the rear portion of the first link 52, the front portion of the second link 53, and the rear portion of the second link 53 constitute the deformable component; the support frame has a radially decreasing contraction working state and a radially increasing expansion working state. When the support frame is in the expansion working state, the first link 52 and the second link 53 intersect and there is no rotational pivot for connection at the intersection point. The deformable component has an elastic force that causes the support frame to tend to increase radially.

[0416] This embodiment relates to an expandable component 4 for use in the system (i.e., an expandable component 4 for gastrointestinal ablation therapy, see [link]). Figures 37-12 to 37-16 (as shown) and a device for ablation therapy of the digestive tract, see [reference]. Figures 37-1 to 37-11 and Figure 37-17 As shown. The expandable component 4 is the core component for ablation therapy of the digestive tract; it can conform to the area to be treated and apply an electric field. The embodiments also relate to a system for ablation therapy of the digestive tract, comprising: Figures 37-1 to 37-11 The device shown for ablation treatment of the digestive tract also includes a signal generator configured to generate an electrical signal for generating electric field energy. The signal generator is electrically connected to a plurality of electrodes 7 disposed on an electrode membrane 6 for supplying power to it.

[0417] Reference Figures 37-1 to 37-11The device for gastrointestinal ablation therapy includes an inner guide rod 1, which is a slender rod-shaped component with a cavity provided therein so that a guide wire can pass through during the procedure.

[0418] The device for gastrointestinal ablation therapy includes a central catheter 2, which is a slender, hollow tubular component. The central catheter 2 is sleeved on the inner guide rod 1, and the central catheter 2 can rotate relative to the inner guide rod 1, with the inner guide rod 1 serving as its axis of rotation.

[0419] The device for gastrointestinal ablation therapy includes an outer catheter 3, which is a slender, hollow tubular component. The outer catheter 3 is fitted onto the middle catheter 2, and the outer catheter 3 is rotatable relative to the middle catheter 2. The outer catheter 3 is fixed relative to the inner guide rod 1, and when the middle catheter 2 rotates relative to the inner guide rod 1, the middle catheter 2 also rotates within the outer catheter 3.

[0420] The system for gastrointestinal ablation therapy includes an expandable component 4. (See reference...) Figures 37-12 to 37-16 The expandable component 4 used for ablation therapy of the digestive tract has a contraction working state and an expansion working state. The expandable component 4 includes a support frame 5 and an electrode membrane 6, on which multiple electrodes 7 are disposed.

[0421] The support frame 5 includes a front connector, a rear connector, and multiple support units 51. In this embodiment, the front connector is a front connecting ring 12 with a ring structure, and the rear connector is also a rear connecting ring 13 with a ring structure. The front connector and / or the rear connector can also adopt other non-ring structures. Multiple support units 51 are each connected to a front connector and each support unit 51 is also connected to a rear connector. The front connecting ring 12 and the rear connecting ring 13 are spaced apart; the multiple support units 51 are spaced apart along the circumferential direction of the front connecting ring 12 or the rear connecting ring 13 (the circumferential direction of the inner guide rod 1 or the middle guide tube 2). All or part of the multiple support units 51 can deform, thereby driving the electrode film 6 to expand outward or contract inward. The number of support units 51 can be 3, 4, 5, 6, 8 or more, etc., and is not limited here.

[0422] At least one of the multiple support units 51 includes an outer support rod 20, a first connecting rod 52, and a second connecting rod 53. The front end 52a of the first connecting rod 52 is connected to the front connecting ring 12, and the rear end 52b of the first connecting rod 52 is connected to the rear end of the outer support rod 20. The front end 53a of the second connecting rod 53 is connected to the front end of the outer support rod 20, and the rear end 53b of the second connecting rod 53 is connected to the rear connecting ring 13. The first connecting rod 52, the second connecting rod 53, the front connecting ring 12, and the rear connecting ring 13 constitute the inner support frame 5. The first connecting rod 52 and the second connecting rod 53 form a cross-shaped structure (also known as an X-shaped structure), similar to scissors. The connection relationship between the first connecting rod 52 and the second connecting rod 53 is not limited. In this embodiment, the first connecting rod 52 and the second connecting rod 53 are not directly connected or connected via a pivot.

[0423] The support frame 5, which has a radially decreasing contraction working state and a radially increasing expansion working state, includes multiple outer support rods 20 and an inner support frame 5 connected to the outer support rods 20. Each outer support rod 20 and the corresponding inner support frame 5 constitute a linkage mechanism. The inner support frame 5 includes multiple first connecting rods 52, multiple second connecting rods 53, a front connecting ring 12 located at the front, and a rear connecting ring 13 located at the rear. At least one linkage mechanism is an X-type linkage mechanism. In the X-type linkage mechanism, the rear end of the first connecting rod 52 is fixedly connected to the rear of the outer support rod 20, and the front end of the first connecting rod 52 is fixedly connected to the front connecting ring 12. The front end of the second connecting rod 53 is fixedly connected to the front of the outer support rod 20, and the rear end of the second connecting rod 53 is fixedly connected to the rear connecting ring 13. In this embodiment, the support frame 5 is integrally formed, that is, the fixed connection relationship between the outer support rods 20 and the internal components of the inner support frame 5 is specifically achieved through integral forming. Furthermore, in this embodiment, all the linkage mechanisms in the entire support frame 5 are X-shaped linkage mechanisms. The rear end of the first link 52 is fixedly connected to the rear end of the outer support rod 20, and the front end of the second link 53 is fixedly connected to the front end of the outer support rod 20.

[0424] The front portion of the first link 52 is provided with or configured as a deformable component, and / or the rear portion of the first link 52 is provided with or configured as a deformable component, and / or the front portion of the second link 53 is provided with or configured as a deformable component, and / or the rear portion of the second link 53 is provided with or configured as a deformable component. That is, at least one of the four components—the front portion of the first link 52, the rear portion of the first link 52, the front portion of the second link 53, and the rear portion of the second link 53—is provided with or configured as (i.e. constitutes) a deformable component. The deformable component can adopt the solutions mentioned in other embodiments of this disclosure, such as processing one or more of the materials of the four components to form an elastic force at the corresponding position, or adding an external elastic element (e.g., a torsion spring) to one or more of the above positions to achieve the function of configuring a deformable component. In this embodiment, the front portion of the first link 52, the rear portion of the first link 52, the front portion of the second link 53, and the rear portion of the second link 53 all constitute deformable components. In this embodiment, by heating and shaping the support frame 5 while it is in an expanded working state, elastic deformable parts are formed at the above four positions. The corresponding elastic force causes the support frame 5 to change toward the expanded working state during heating and shaping.

[0425] When the expandable component is in the expanded working state, the first link 52 and the second link 53 intersect and there is no rotating pivot for connection at or near the intersection point.

[0426] The electrode membrane 6 is wound around multiple support units 51. The inner end of the electrode membrane 6 is connected to the support frame 5, and the outer end of the electrode membrane 6 is a free end, which can be connected to the outer conduit 3. The first connecting rod 52 and / or the second connecting rod 53 have elastic sections, which are also deformable parts. They are elastic and can return to their predetermined initial shape after the external force is removed. When the expandable component 4 is in the contracted working state, the elastic sections tend to move the outer support rod 20 outward along the diameter direction of the front connecting ring 12 or the rear connecting ring 13, so as to drive the electrode membrane 6 to expand along the diameter direction and switch to the expansion working state. The aforementioned elastic sections are made of a rigid material that has undergone shaping treatment and has a predetermined shape. Moreover, once the external force acting on the first connecting rod 52 and the second connecting rod 53 is removed and the elastic section is released, the elastic section naturally returns to its predetermined shape. For example, the elastic section can be made of metal material, which has been pre-heated and shaped to have a predetermined shape that is inclined / bent outward. Therefore, when the support frame 5 is in a released state without any external force applied, the first link 52 bends outward and tilts relative to the front connecting ring 12, and the second link 53 bends outward and tilts relative to the rear connecting ring 13, thereby pushing the outer support rod 20 outward so that the outer support rod 20 is located outside the front connecting ring 12 and the rear connecting ring 13.

[0427] The elastic segment includes at least one of the front end 52a and rear end 52b of the first link 52, and the front end 53a and rear end 53b of the second link 53. The front end 52a of the first link 52 and the front connecting ring 12 are integral, and the front end 52a of the first link 52 is elastic and has a tendency to move outward relative to the front connecting ring 12. And / or, the rear end 52b of the first link 52 and the rear end of the outer support rod 20 are integral, and the rear end 52b of the first link 52 is elastic and has a tendency to push the outer support rod 20 outward. And / or, the rear end 53b of the second link 53 and the rear connecting ring 13 are integral, and the rear end 53b of the second link 53 is elastic and has a tendency to move outward relative to the rear connecting ring 13; And / or, the front end 53a of the second link 53 and the front end of the outer support rod 20 are integral, and the front end 53a of the second link 53 is elastic and has a tendency to push the outer support rod 20 outward.

[0428] In this embodiment, all the support units 51 include the aforementioned outer support rod 20, first connecting rod 52 and second connecting rod 53. All the support units 51 work together to stretch the electrode membrane 6 outward, achieving a uniform support effect. The electrode membrane 6 and the digestive tract area to be treated have the best fit effect.

[0429] In this specific embodiment, the support frame 5 is made by cutting and shaping a tube. When the expandable component 4 is in the retracted working state, the support frame 5 is assembled into a tubular shape, as shown below. Figure 37-15 and Figure 37-16 As shown. The pipe is a metal pipe, and more specifically, it is a pipe of uniform diameter, with the diameter being the same everywhere. The metal pipe is preferably made of stainless steel, nickel alloy, titanium alloy, or nickel-titanium alloy. The material of the metal pipe is preferably a metal material with good elasticity after heat setting, capable of maintaining the predetermined shape, and thus having the elasticity to return to the initial shape after being subjected to force.

[0430] The front connecting ring 12 is formed from the front end of the pipe, specifically as a ring-shaped component. The rear connecting ring 13 is formed from the rear end of the pipe, specifically as a ring-shaped component. The rear connecting ring 13 is located behind the front connecting ring 12, and there is a gap between them, which is variable. That is, the front connecting ring 12 and the rear connecting ring 13 can move closer to each other or further away. For example, the rear connecting ring 13 can move relative to the front connecting ring 12 in the front-back direction to change the distance between them. The first connecting rod 52, the second connecting rod 53, and the outer support rod 20 are formed by cutting the main body of the pipe located between its front and rear ends along its length direction. After cutting, the first connecting rod 52, the second connecting rod 53, and the outer support rod 20 are as a whole elongated strip in the front-back direction (the length direction of the pipe). After shaping, the first connecting rod 52 and the second connecting rod 53 are in a predetermined shape that is inclined / bent outward.

[0431] The first connecting rod 52 and the second connecting rod 53 are located on opposite sides of the outer support rod 20. The front connecting ring 12, the first connecting rod 52, the outer support rod 20, the second connecting rod 53, and the rear connecting ring 13 are connected sequentially and are integral. During the above-mentioned cutting, the connection between the front connecting ring 12 and the first connecting rod 52 is not cut off, as they are integral; similarly, the connection between the first connecting rod 52 and the outer support rod 20, the connection between the outer support rod 20 and the second connecting rod 53, and the connection between the second connecting rod 53 and the rear connecting ring 13 are also not cut off. Each support unit 51 is integral, and each support unit 51, the front connecting ring 12, and the rear connecting ring 13 are also integral. The entire support frame 5 is a single integral part. The aforementioned elastic segment is formed by bending the front part 615a and the rear part 615b of the first connecting rod 52 and the front part 616a and the rear part 616b of the second connecting rod 53 outwards. Specifically, the first link 52 is shaped by heating, so that when in the retracted working state, the first link 52 tends to bend outward relative to the front connecting ring 12; the second link 53 is shaped by high temperature, so that when in the retracted working state, the second link 53 tends to bend outward relative to the rear connecting ring 13.

[0432] Furthermore, in this embodiment, the width of the front and rear parts of the outer support rod 20 is greater than the width of the front part 615a and the rear part 615b of the first connecting rod 52 connected to it and the width of the front part 616a and the rear part 616b of the second connecting rod 53 connected to it. The width of the rear part 615b of the first connecting rod 52 is less than the width of the middle part of the first connecting rod 52, and the width of the front part 615a of the first connecting rod 52 is less than the width of the middle part of the first connecting rod 52. The width of the rear portion 616b of the second link 53 is smaller than the width of the middle portion of the second link 53, and the width of the front portion 616a of the second link 53 is smaller than the width of the middle portion of the second link 53. The width of the front portion 615a and / or the rear portion 615b of the first link 52 is smaller than the width of its middle portion, so as to facilitate bending and shaping of the front portion 615a and / or the rear portion 615b of the first link 52. The width of the front portion 616a and / or the rear portion 616b of the second link 53 is smaller than the width of its middle portion, so as to facilitate bending and shaping of the front portion 616a and / or the rear portion 616b of the second link 53. The width of the rear portion of the outer support rod 20 is larger than the width of its middle portion, and the width of the front portion of the outer support rod 20 is larger than the width of its middle portion. Through holes for fixing the inner ends of the electrode film are respectively provided at both ends of the outer support rod 20 as connecting holes. Furthermore, the width of the front and / or rear portion of the outer support rod 20 is greater than the width of its middle portion. Connecting holes are provided on the front and / or rear ends of the outer support rod 20, on the front connecting ring 12, and on the rear connecting ring 13, to facilitate connection with other components.

[0433] In this embodiment, reference Figure 37-17 Both the front connecting ring 12 and the rear connecting ring 13 are connected to the middle guide tube 2, and at least one of them is movably sleeved on the middle guide tube 2 so as to be able to rotate relative to the middle guide tube 2 and move in the front-rear direction. In this case, the inner guide rod 1 can be omitted. (Refer to...) Figure 37-22 As shown. Alternatively, in some embodiments, the front connecting ring 12 is movably connected to the inner guide rod 1, and the rear connecting ring 13 is connected to the middle guide tube 2. Specifically, as shown... Figure 37-4 As shown, the front connecting ring 12 is movably sleeved on the inner guide rod 1, and allows the inner guide rod 1 to rotate relative to the front connecting ring 12, that is, the front connecting ring 12 can be slid back and forth and rotate circumferentially on the inner guide rod 1; the rear connecting ring 13 is fixed to the front end of the middle guide tube 2.

[0434] The electrode membrane 6 is provided with multiple electrodes 7 for receiving electrical signals, and the electrode membrane 6 is spirally wound around the support frame 5. When the expandable component 4 is in the contracted working state, the electrode membrane 6 contracts and is wound in multiple turns around the support frame 5, as shown below. Figures 37-8 to 37-11As shown. The outer ring of the electrode membrane 6 is tightly attached to the inner ring, forming a spiral spring shape, that is, adjacent rings of electrode membrane 6 are tightly attached. The inner end of the electrode membrane 6 (i.e., the end of the innermost ring of electrode membrane 6) is fixedly or rotatably connected to the support frame 5, and the outer end of the electrode membrane 6 (i.e., the end of the outermost ring of electrode membrane 6) is connected to a connector to connect to the inner guide rod 1 or the outer catheter 3 of the device used for digestive tract ablation therapy, so that the electrode membrane 6 is wound around the support frame 5 in a spread-out state. The inner end of the electrode membrane 6 is parallel to the inner guide rod 1, and the outer end of the electrode membrane 6 is also parallel to the inner guide rod 1. In this embodiment, the front side edges of each ring of electrode membrane 6 are aligned, and the rear side edges of each ring of electrode membrane 6 are also aligned, that is, the electrode membrane 6 is spirally wound around the support frame 5. When the expandable component 4 transitions from a contracted working state to an expanded working state, the electrode membrane 6 also transitions from contraction to expansion. After expansion, the total number of turns of the electrode membrane 6 decreases, and the diameter of each turn of the electrode membrane 6 increases. Ultimately, in the expanded working state, the number of turns of the electrode membrane 6 is greater than 1 turn but less than 2 turns. Figure 37-7 As shown. The support frame 5 in the expanded working state supports the electrode membrane 6. The outermost cylindrical electrode membrane 6 can be stretched and adhered to the inner wall of the digestive tract, especially the inner wall of the duodenum. After receiving an electrical pulse from the signal generator, the electrode 7 discharges to ablate the inner wall tissue. The electrical signals generated by the signal generator include electrical signals for heating the target tissue, pulse signals for electric field ablation of the target tissue, radiofrequency ablation signals, etc. The method and principle for driving the contraction and expansion of the electrode membrane 6 can be found in patent application CN2025113237920, or in the foregoing embodiments of this disclosure.

[0435] Specifically, the connector includes an outer end rod 14 (electrode membrane connector) and a connecting strip 15 (deformable connector) that is rigid in the circumferential direction and deformable (e.g., bending or telescoping). The outer end rod 14 is parallel to the middle guide tube 2 and connected to the outer end of the electrode membrane 6. The front end of the connecting strip 15 is connected to the rear end of the outer end rod 14, and the rear end of the connecting strip 15 is connected to the outer guide tube 3. During the transformation of the expandable component 4 from a contracted working state to an expanded working state, the outer end rod 14 gradually moves away from the middle guide tube 2. During the transformation of the support frame 5 from an expanded working state to a contracted working state, the outer end rod 14 gradually moves closer to the middle guide tube 2. The outer support rod 20 is parallel to the middle guide tube 2.

[0436] The connecting bar 15 includes multiple (e.g., two) sections 17. The front end of an adjacent subsequent section 17 is pivotally connected to the rear end of the preceding section 17 to form a chain. The front end of the foremost section 17 is pivotally connected to the rear end of the outer end rod 14. The rear end of the last section 17 is pivotally connected to the outer guide tube 3. The axis of each pivot is perpendicular to the inner guide rod 1 in space. When the expandable component 4 is in the contracted working state, the connecting bar 15 is bent inward or outward. When the expandable component 4 is in the expanded working state, the connecting bar 15 is generally straight.

[0437] The system for gastrointestinal ablation therapy includes an operating handle 28, with the rear (proximal) ends of the inner guide rod 1 and the outer catheter 3 connected to the operating handle 28. The middle catheter 2 is connected to a rotating component (knob) on the operating handle 28, which can rotate relative to the operating handle 28, thereby driving the middle catheter 2 to rotate.

[0438] The device / system for ablation therapy of the digestive tract includes an actuator connected to an outer catheter 3. When the outer catheter 3 rotates relative to the middle catheter 2, the actuator drives the connector to rotate around the support frame 5. The outer end 9 of the electrode membrane 6 on the support frame 5 rotates relative to the inner end 8 of the electrode membrane 6, thereby controlling the expansion or contraction of the support frame 5. In the human digestive tract, when the electrode membrane 6 expands or contracts, the outermost electrode membrane 6 moves radially and rotates around the support frame 5. The friction generated by the electrode membrane 6 contacting the inner wall of the intestine during rotation requires increased driving force from the actuator and elastic force from the rigid elastic material. The actuator can be the one disclosed in patent application CN2025113237920. Its specific structure and principle can be found in patent application CN2025113237920. Figure 34 , Figure 26 The actuator can also be referred to the foregoing embodiments of this disclosure, along with related textual descriptions.

[0439] The method for fabricating the expandable component 4 described above includes the fabrication of the support frame 5. The support frame 5 is specifically fabricated through the following steps: S1. The pipe is cut through to form a front connecting ring, a rear connecting ring, and multiple sets of first connecting rods 52, outer support rods 20, and second connecting rods 53 disposed between the front connecting ring and the rear connecting ring. The two ends of the outer support rods 20 are adjacent to and spaced apart from the front connecting ring 12 and the rear connecting ring 13, respectively. Specifically, step S1 includes the following steps: S11. Provide a pipe; S12. Cut the pipe along its length to form multiple cutting lines 54. The multiple cutting lines 54 are spaced apart along the circumference of the pipe to form the first connecting rod 52, the outer support rod 20, and the second connecting rod 53. The starting point of each cutting line 54 is a distance from the front edge of the pipe so that the front end of the pipe forms a front connecting ring 12. The ending point of each cutting line 54 is a distance from the rear edge of the pipe so that the rear end of the pipe forms a rear connecting ring 13. S13. Cut along the circumference of the pipe to separate the rear end 52b of the first connecting rod 52 and the rear end of the outer support rod 20 from the rear connecting ring 13, and to separate the front end 53a of the second connecting rod 53 and the front end of the outer support rod 20 from the front connecting ring 12. S2. Shaping, so that the first connecting rod 52 is tilted outward relative to the front connecting ring 12, and the second connecting rod 53 is tilted outward relative to the rear connecting ring 13, to obtain the support frame 5.

[0440] In step S2, the cut pipe is heated and shaped in the expansion working state, so that the deformable parts of the shaped support frame have elastic force in the contraction working state. That is, the cut pipe is heated and shaped so that the first connecting rod 52 and the second connecting rod 53 have a predetermined shape of outward bending.

[0441] Step S3: After step S2 is performed, the support frame is converted to a retractable working state, restoring it to the shape of the cut tubular material, so that it can be installed in the device / system for digestive tract ablation therapy.

[0442] The aforementioned expandable component 4 improves the fit between the electrode 7 and the intestinal lining. Simultaneously, the front connecting ring 12, the first connecting rod 52, the outer support rod 20, the second connecting rod 53, and the rear connecting ring 13 are sequentially connected, allowing for a single, integrated design. This simplifies the manufacturing process and reduces costs. The cross-shaped structure formed by the first connecting rod 52 and the second connecting rod 53 significantly shortens the length of the support frame 5 in its contracted state compared to existing support frames 5, facilitating its transport within the digestive tract and reducing the risk of the expandable component scratching the digestive tract during transport.

[0443] This disclosure also provides a system for ablation therapy of the digestive tract having the foregoing embodiments, see reference. Figure 1As shown, it includes a device for ablation therapy of the digestive tract, and further includes: a signal generator 31 configured to generate electrical signals for electric field energy. The electrical signals generated by the signal generator include electrical signals for heating target tissue, pulse signals for electric field ablation of target tissue, radiofrequency ablation signals, etc. The signal generator 31 is electrically connected to the electrodes 7 on the electrode membrane 6 via a means such as wires. The signal generator 31 generates pulse signals, and the discharge of the electrodes 7 can ablate the villi of the inner wall of the digestive tract. The signal generator 31, the method of transmitting electrical signals from the signal generator 31 to the electrodes 7, and the wiring method can all adopt existing technologies. For example, the wires between the electrodes 7 and the operating handle 28 can be arranged in the space between the outer catheter 3 and the middle catheter 2. It should be noted that information such as the material and thickness of the electrode membrane 6, the material and arrangement of the electrodes 7, the electrical connection method of the electrodes 7, and the electrical signal parameters and control methods used in ablation therapy can all be implemented using mature solutions in the prior art, and can be routinely selected and adjusted according to specific treatment needs. The above content is not the core improvement of this disclosure, and those skilled in the art can implement it directly based on existing technology, so it will not be elaborated further.

[0444] The apparatus for ablation treatment of the human duodenum, as described in the foregoing embodiments, also provided in this disclosure is particularly suitable for treating type 2 diabetes. Specifically, this disclosure also provides the use of the apparatus for ablation treatment of the human duodenum in treating type 2 diabetes. In some embodiments, a corresponding method for treating type 2 diabetes is provided, which uses the aforementioned apparatus for ablation treatment of the human duodenum. After delivering the expandable component 4 in a contracted working state to the target location, the support frame 5 is rotated relative to the outer end of the electrode membrane 6 by a rotating component (for example, in some embodiments, the central conduit 2, which serves as the rotating component, is rotated, causing the support frame 5 to rotate relative to the outer end of the electrode membrane 6; in other embodiments, the outer conduit 3, which serves as the reference component, is rotated, causing the support frame 5 to rotate relative to the outer end of the electrode membrane 6). This causes the wound electrode membrane 6 to expand radially, and the support frame 5 also expands radially under the action of a rigid elastic material (or a deformable component) until the desired expansion working state is achieved. The human duodenum is then ablated / treated through the electrodes 7 on the electrode membrane 6.

[0445] In some embodiments, after treatment or processing is completed, the support frame 5 is rotated again relative to the outer end of the electrode membrane 6, so that the wound electrode membrane 6 contracts radially, and the electrode membrane 6 presses the support frame 5 to contract radially at the same time, until the contraction working state is reached; the expandable component 4 is removed from the human body from the target position.

[0446] The apparatus for ablation treatment of the human duodenum, as described in the foregoing embodiments, provided in this disclosure is particularly suitable for treating obesity. Specifically, this disclosure also provides the use of the apparatus for ablation treatment of the human duodenum in treating obesity. In some embodiments, a corresponding method for treating obesity is provided, which uses the aforementioned apparatus for ablation treatment of the human duodenum. After delivering the expandable component 4 in a contracted working state to the target location, the support frame 5 is rotated relative to the outer end of the electrode membrane 6 by a rotating component (for example, in some embodiments, the central conduit 2, which serves as the rotating component, is rotated, causing the support frame 5 to rotate relative to the outer end of the electrode membrane 6; in other embodiments, the outer conduit 3, which serves as the reference component, is rotated, causing the support frame 5 to rotate relative to the outer end of the electrode membrane 6). This causes the wound electrode membrane 6 to expand radially, and the support frame 5 also expands radially under the action of a rigid elastic material (or a deformable component) until the desired expansion working state is achieved. The human duodenum is then ablated / treated through the electrodes 7 on the electrode membrane 6.

[0447] In some embodiments, after treatment or processing is completed, the support frame 5 is rotated again relative to the outer end of the electrode membrane 6, so that the wound electrode membrane 6 contracts radially, and the electrode membrane 6 presses the support frame 5 to contract radially at the same time, until the contraction working state is reached; the expandable component 4 is removed from the human body from the target position.

[0448] This disclosure also provides the use of the aforementioned device for ablation treatment of the human duodenum in the treatment of non-alcoholic fatty liver disease. Specifically, this disclosure provides a method for treating non-alcoholic fatty liver disease, which uses a device for ablation treatment of the human duodenum, such as those provided in the foregoing embodiments. After delivering the expandable component 4 in a contracted working state to the target position, the support frame 5 is rotated relative to the outer end of the electrode membrane 6 by a rotating component (for example, in some embodiments, the central conduit 2, which serves as the rotating component, is rotated, causing the support frame 5 to rotate relative to the outer end of the electrode membrane 6; in other embodiments, the outer conduit 3, which serves as the reference component, is rotated, causing the support frame 5 to rotate relative to the outer end of the electrode membrane 6). This causes the wound electrode membrane 6 to expand radially, and the support frame 5 also expands radially under the action of a rigid elastic material (or a deformable component) until the desired expansion working state is achieved. The human duodenum is then ablated / treated through the electrodes 7 on the electrode membrane 6.

[0449] In some embodiments, after treatment, the support frame 5 is rotated again relative to the outer end of the electrode membrane 6, causing the wound electrode membrane 6 to contract radially. The electrode membrane 6 also compresses the support frame 5 to contract radially until it reaches the contraction working state; the expandable component 4 is then removed from the human body from the target position.

[0450] The above embodiments are only for illustrating the technical concept and features of this disclosure, and are intended to enable those skilled in the art to understand the content of this disclosure and implement it accordingly. They should not be construed as limiting the scope of protection of this disclosure. All equivalent changes or modifications made in accordance with the spirit and essence of this disclosure should be included within the scope of protection of this disclosure.

Claims

1. A device for ablation therapy of the digestive tract, characterized in that, It includes: Slender inner guide rod; A slender central guide tube is sleeved on the inner guide rod, and the central guide tube is rotatably disposed relative to the inner guide rod; A slender outer conduit is sleeved on the middle conduit, and the middle conduit is rotatably disposed relative to the outer conduit; An expandable component surrounds the inner guide rod. The expandable component includes a support frame and a flexible electrode membrane. The expandable component has a radially decreasing contraction working state and a radially increasing expansion working state. The rear end of the support frame is connected to the central guide tube. The support frame has a deformable component, and the deformable component changes shape when the support frame changes between the contraction and expansion working states. The deformable component is made of a rigid elastic material, and the deformable component gives the support frame a radially outward elastic force that changes from the contraction to the expansion working state. The electrode membrane has multiple electrodes for receiving electrical signals. The electrode membrane is spirally wound around the support frame. The inner end of the electrode membrane is connected to the support frame, and the outer end of the electrode membrane is connected to the inner guide rod via a connector, or / and the outer end of the electrode membrane is connected to the outer guide tube via a connector.

2. The device for ablation therapy of the digestive tract according to claim 1, characterized in that: It also includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected middle guide tube to rotate forward relative to the outer guide tube, so that while the electrode membrane expands radially, the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected middle guide tube to rotate in the opposite direction relative to the outer guide tube, so that while the electrode membrane contracts radially, the electrode membrane also compresses the supporting frame to contract radially at the same time.

3. The device for ablation therapy of the digestive tract according to claim 2, characterized in that: The actuator is connected to the middle conduit and is used to drive the support frame to rotate relative to the outer conduit when the middle conduit rotates relative to the outer conduit.

4. The device for ablation therapy of the digestive tract according to claim 1, characterized in that: It also includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected outer conduit to rotate in the opposite direction relative to the middle conduit, so that while the electrode membrane expands radially, the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected outer conduit to rotate in the forward direction relative to the middle conduit, so that while the electrode membrane contracts radially, the electrode membrane also compresses the supporting frame to contract radially at the same time.

5. The apparatus for ablation therapy of the digestive tract according to claim 4, characterized in that: The actuator is connected to the outer conduit and is used to drive the connector to rotate around the support frame when the outer conduit rotates relative to the middle conduit.

6. The apparatus for ablation therapy of the digestive tract according to claim 1, characterized in that: The supporting frame has a front end and a rear end. The front end of the supporting frame is sleeved on the inner guide rod. The front end of the supporting frame and the inner guide rod are slidable in the front-back direction and rotatable in the circumferential direction. The rear end of the supporting frame is connected to the middle guide tube.

7. The apparatus for ablation therapy of the digestive tract according to claim 1, characterized in that: The supporting frame has a front end and a rear end. The front end of the supporting frame is sleeved on the inner guide rod. The front end of the supporting frame and the inner guide rod are slidable in the front-back direction and non-rotatable in the circumferential direction. The rear end of the supporting frame is connected to the middle guide tube.

8. The apparatus for ablation therapy of the digestive tract according to claim 1, characterized in that: The supporting frame has a front end and a rear end. The front end of the supporting frame is sleeved on the inner guide rod. The front end of the supporting frame and the inner guide rod are rotatably and positioned in the front-back direction. The rear end of the supporting frame is connected to the middle guide tube.

9. The apparatus for ablation therapy of the digestive tract according to claim 1, characterized in that: The supporting frame has a front connecting ring, which forms the front end of the supporting frame. The front connecting ring is sleeved on the inner guide rod. The front connecting ring is slidably disposed relative to the inner guide rod in the front-rear direction and rotatably disposed in the circumferential direction. The rear end of the supporting frame is connected to the middle guide tube; and / or, the front middle part of the supporting frame is pivotally connected to the front connecting ring, and the pivot of the pivot connection is perpendicular to the inner guide rod.

10. The apparatus for ablation therapy of the digestive tract according to claim 1, characterized in that: The supporting frame has a front connecting ring, which forms the front end of the supporting frame. The front connecting ring is sleeved on the inner guide rod. The front connecting ring is configured to allow sliding in the front-back direction but prohibit rotation in the circumferential direction relative to the inner guide rod. The rear end of the supporting frame is connected to the middle guide tube; and / or, the front middle part of the supporting frame is pivotally connected to the front connecting ring, and the pivot connection is perpendicular to the inner guide rod.

11. The apparatus for ablation therapy of the digestive tract according to claim 1, characterized in that: The supporting frame has a front connecting ring, which forms the front end of the supporting frame. The front connecting ring is sleeved on the inner guide rod and is rotatably and positionally disposed on the inner guide rod in the front-rear direction. The rear end of the supporting frame is connected to the middle guide tube; and / or, the front middle part of the supporting frame is pivotally connected to the front connecting ring, and the pivot of the pivot connection is perpendicular to the inner guide rod.

12. The apparatus for ablation therapy of the digestive tract according to claim 6, 7, 9, or 10, characterized in that: The rear end of the supporting frame is fixedly connected to the central conduit; or, the rear end of the supporting frame is pivotally connected to the central conduit, and the pivot is perpendicular to the central conduit.

13. The apparatus for ablation therapy of the digestive tract according to claim 6, 7, 8, 9, 10, or 11, characterized in that: The rear end of the support frame is sleeved on the central guide tube, and the rear end of the support frame and the central guide tube are connected in a way that allows sliding along the front-back direction but cannot rotate relative to each other.

14. The apparatus for ablation therapy of the digestive tract according to claim 6, 7, 8, 9, 10, or 11, characterized in that: The supporting frame has a rear connecting ring, which forms the rear end of the supporting frame. The rear connecting ring is sleeved on the middle guide tube, and the rear connecting ring and the middle guide tube are slidably connected in the front-back direction but cannot be rotated relative to each other; and / or, the rear middle part of the supporting frame is pivotally connected to the rear connecting ring, and the pivot of the pivot connection is perpendicular to the inner guide rod.

15. The apparatus for ablation therapy of the digestive tract according to claim 1, characterized in that: The front end of the support frame is a front connecting ring, which is sleeved on the inner guide rod; the rear end of the support frame is a rear connecting ring, which is sleeved on the middle guide tube.

16. A device for ablation therapy of the digestive tract, characterized in that: It includes: Slender central duct; A slender outer conduit is sleeved on the middle conduit, and the middle conduit is rotatably disposed relative to the outer conduit; An expandable component surrounds the central conduit. The expandable component includes a supporting frame and a flexible electrode membrane. The expandable component has a radially decreasing contraction working state and a radially increasing expansion working state. The supporting frame is connected to the central conduit and has a deformable component. When the supporting frame changes between the contraction and expansion working states, the deformable component changes shape. The deformable component is made of a rigid elastic material, and the deformable component gives the supporting frame a radially outward elastic force as it changes from the contraction to the expansion working state. The electrode membrane has multiple electrodes for receiving electrical signals. The electrode membrane is spirally wound around the supporting frame. The inner end of the electrode membrane is connected to the supporting frame, and the outer end of the electrode membrane is connected to the outer conduit via a connector.

17. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: It also includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected middle conduit to rotate forward relative to the outer conduit, causing the electrode membrane to expand radially while the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected middle conduit to rotate in the opposite direction relative to the outer conduit, causing the electrode membrane to contract radially while the electrode membrane compresses the supporting frame to also contract radially.

18. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: It also includes an actuator that, during the transition of the expandable component from a contracted working state to an expanded working state, drives the connected outer conduit to rotate in the opposite direction relative to the middle conduit, so that while the electrode membrane expands radially, the supporting frame also expands radially under the action of the rigid elastic material; during the transition of the expandable component from an expanded working state to a contracted working state, the actuator drives the connected outer conduit to rotate in the forward direction relative to the middle conduit, so that while the electrode membrane contracts radially, the electrode membrane also compresses the supporting frame to contract radially.

19. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The supporting frame includes multiple inner support rods and multiple outer support rods parallel to the central guide tube and connected to the ends of the inner support rods. The multiple outer support rods are distributed in a cylindrical shape around the central guide tube. The inner middle section of each inner support rod is fixedly connected to the central guide tube. At least one of the front and rear ends of the inner support rod is slidably connected to a corresponding outer support rod in the front-rear direction. When the supporting frame is in the expanded working state, the inner support rods are in an arc shape with their openings facing outwards. When the supporting frame is in the contracted working state, the inner support rods are in a roughly straight shape.

20. The apparatus for ablation therapy of the digestive tract according to claim 19, characterized in that: The outer support rod has a front extension section extending forward toward the front end of the inner support rod, and / or the outer support rod has a rear extension section extending backward toward the rear end of the inner support rod, such that when the support frame is in a retracted working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

21. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The supporting frame includes multiple annular rods and multiple outer support rods parallel to the central guide tube. The inner side of each annular rod is fixedly connected to the central guide tube, and the outer side of each annular rod is fixedly connected to a corresponding outer support rod. When the supporting frame is in the expansion working state, the annular rods are open annular shapes, and when the supporting frame is in the contraction working state, the annular rods are flattened into a roughly straight shape.

22. The apparatus for ablation therapy of the digestive tract according to claim 21, characterized in that: The outer support rod has a front extension section extending forward toward the outer side of the ring rod, and / or the outer support rod has a rear extension section extending backward toward the outer side of the ring rod, such that when the support frame is in the retracted working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the ring rod in the front-rear direction, and the front end of the ring rod is located behind the front end of the outer support rod, or the front end of the ring rod is aligned with the front end of the outer support rod; the rear end of the ring rod is located in front of or aligned with the rear end of the outer support rod.

23. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The supporting frame includes multiple inner support rods and multiple outer support rods parallel to the central guide tube. The multiple outer support rods are distributed in a cylindrical shape around the central guide tube. The inner middle section of each inner support rod is fixedly connected to the central guide tube, and the two outer ends of each inner support rod are fixedly connected to a corresponding outer support rod. When the supporting frame is in the expanded working state, the front part of the inner support rod is an arc shape with the opening facing backward, and the rear part of the inner support rod is an arc shape with the opening facing forward. The inner support rods and the outer support rods form a closed ring. When the supporting frame is in the contracted working state, the ring is flattened.

24. The apparatus for ablation therapy of the digestive tract according to claim 23, characterized in that: The outer support rod has a front extension section extending forward toward the front end of the inner support rod, and / or the outer support rod has a rear extension section extending backward toward the rear end of the inner support rod, such that when the support frame is in a retracted working state, the length of the outer support rod in the front-rear direction is greater than or equal to the length of the inner support rod in the front-rear direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

25. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The supporting frame has two ends, a front end and a rear end, one end of which is sleeved on the central guide tube. This end is slidable in the front-back direction and rotatable in the circumferential direction relative to the central guide tube. The other end of the supporting frame is connected to the central guide tube.

26. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: One end of the supporting frame is suspended in the air, and the other end of the supporting frame is connected to the central conduit.

27. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The supporting frame has two ends, a front end and a rear end. One end of the supporting frame is sleeved on the central guide tube. This end and the central guide tube are slidably connected in the front-back direction but cannot be rotated relative to each other. The other end of the supporting frame is connected to the central guide tube.

28. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The support frame has two ends, a front end and a rear end. One end of the support frame is sleeved on the central guide tube. This end is rotatably disposed with respect to the central guide tube in the circumferential direction but cannot slide in the front-back direction. The other end of the support frame is connected to the central guide tube.

29. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The support frame has two ends, a front end and a rear end, one end of which is fixedly connected to the central guide tube, and the other end of which is connected to the central guide tube.

30. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The supporting frame has two parts: a front middle part and a rear middle part. One part of the supporting frame is pivotally connected to a connecting ring, with the pivot perpendicular to the central guide tube. The connecting ring is sleeved on the central guide tube and is slidably arranged relative to the central guide tube in the front-back direction and rotatably arranged in the circumferential direction. The other end of the supporting frame is connected to the central guide tube.

31. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The supporting frame has two parts: a front middle part and a rear middle part. One part of the supporting frame is pivotally connected to a connecting ring, with the pivot perpendicular to the central guide tube. The connecting ring is sleeved on the central guide tube and slides relative to the central guide tube in the front-back direction but is not rotatable in the circumferential direction. The other end of the supporting frame is connected to the central guide tube.

32. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The supporting frame has two parts: a front middle part and a rear middle part. One part of the supporting frame is pivotally connected to a connecting ring, with the pivot perpendicular to the central guide tube. The connecting ring is sleeved on the central guide tube and is rotatably arranged relative to the central guide tube in the circumferential direction and is non-slip in the front-back direction. The other end of the supporting frame is connected to the central guide tube.

33. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The supporting frame has two parts: a front middle part and a rear middle part. One part of the supporting frame is pivotally connected to the central guide tube, with the pivot perpendicular to the central guide tube. The other part of the supporting frame is connected to the central guide tube at its corresponding end.

34. The apparatus for ablation therapy of the digestive tract according to claim 25, 26, 27, 30, 31, or 32, characterized in that: The other end of the supporting frame is fixedly connected to the central guide tube.

35. The apparatus for ablation therapy of the digestive tract according to claim 25, 26, 27, 28, 29, 30, 31, 32, or 33, characterized in that: The other end of the supporting frame is slidably connected to the central guide tube in the front-back direction but cannot be rotated relative to it.

36. The apparatus for ablation therapy of the digestive tract according to claim 27, 29, 31, or 33, characterized in that: The other end of the supporting frame is slidably disposed relative to the central guide tube in the front-back direction and rotatably disposed in the circumferential direction.

37. The apparatus for ablation therapy of the digestive tract according to claim 27 or 31, characterized in that: The other end of the supporting frame is rotatably disposed relative to the central guide tube in the circumferential direction but not slidable in the front-back direction.

38. The apparatus for ablation therapy of the digestive tract according to claim 25, 26, 27, 30, or 31, characterized in that: Another part of the supporting frame is pivotally connected to another connecting ring, the pivot being perpendicular to the central guide tube. The other connecting ring is sleeved on the central guide tube and fixedly connected to it.

39. The apparatus for ablation therapy of the digestive tract according to claim 27 or 31, characterized in that: Another part of the supporting frame is pivotally connected to another connecting ring. The pivot is perpendicular to the central guide tube. The other connecting ring is sleeved on the central guide tube and is rotatably arranged relative to the central guide tube in the circumferential direction but not sliding in the front-back direction.

40. The apparatus for ablation therapy of the digestive tract according to claim 25, 26, 27, 28, 29, 30, 31, 32, or 33, characterized in that: Another part of the supporting frame is pivotally connected to another connecting ring. The pivot is perpendicular to the central guide tube. The other connecting ring is sleeved on the central guide tube and is slidably arranged relative to the central guide tube in the front-back direction but cannot be rotated relative to it.

41. The apparatus for ablation therapy of the digestive tract according to claim 27, 29, 31, or 33, characterized in that: Another part of the supporting frame is pivotally connected to another connecting ring. The pivot is perpendicular to the central guide tube. The other connecting ring is sleeved on the central guide tube and is slidably disposed relative to the central guide tube in the front-back direction and rotatably disposed in the circumferential direction.

42. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: The connector includes an electrode membrane connector and a deformable connector that is rigid and deformable in the circumferential direction. The electrode membrane connector is parallel to the central guide tube and connected to the outer end of the electrode membrane. The front end of the deformable connector is connected to the rear end of the electrode membrane connector, and the rear end of the deformable connector is connected to the outer guide tube. During the process of the support frame changing from a contracted working state to an expanded working state, the electrode membrane connector gradually moves away from the central guide tube. During the process of the support frame changing from an expanded working state to a contracted working state, the electrode membrane connector gradually moves closer to the central guide tube.

43. The apparatus for ablation therapy of the digestive tract according to claim 42, characterized in that: The front end of the deformable connector and the rear end of the electrode film connector are selected from the following connection structures: pivot connection, fixed connection, slidable connection in the front-back direction, and pivotal and slidable connection, wherein the pivot of the pivotal connection is perpendicular to the middle conduit; the rear end of the deformable connector and the outer conduit are selected from the following connection structures: pivot connection, fixed connection, slidable connection in the front-back direction, and pivotal and slidable connection, wherein the pivot of the pivotal connection is perpendicular to the middle conduit.

44. The apparatus for ablation therapy of the digestive tract according to claim 42, characterized in that: When the supporting frame changes between the contracted working state and the expanded working state, the distance between the front and rear ends of the deformable connector can be variably set.

45. The apparatus for ablation therapy of the digestive tract according to claim 42, characterized in that: The deformable connector is a rigid elastic sheet with elasticity. When the supporting frame is in a contracted working state, the deformable connector is bent.

46. ​​The apparatus for ablation therapy of the digestive tract according to claim 42, characterized in that: The deformable connector includes multiple sections of rod, with the ends of two adjacent sections pivotally connected to form a chain. The outer conduit is pivotally connected to the rear end of an adjacent section of rod, and the rear end of the electrode film connector is pivotally connected to the front end of an adjacent section of rod. Each pivot is perpendicular to the middle conduit.

47. The apparatus for ablation therapy of the digestive tract according to claim 42, characterized in that: The deformable connector includes multiple sections of rod, which are slidably connected to form a telescopic rod. The rear end of the electrode film connector is pivotally connected to the front end of an adjacent section of rod, and the outer conduit is pivotally connected to the rear end of an adjacent section of rod. The axis of each pivot is perpendicular to the middle conduit.

48. The apparatus for ablation therapy of the digestive tract according to claim 16, characterized in that: It also includes an inner guide rod, on which the middle guide tube is sleeved, and the middle guide tube is rotatably disposed relative to the inner guide rod.

49. The apparatus for ablation therapy of the digestive tract according to claim 1 or 48, characterized in that: The inner guide rod is fixedly disposed with the outer guide tube. A front guide cap is fixedly connected to the front end of the inner guide rod. The inner guide rod is a tubular body with a guide wire cavity. The center of the front guide cap also has a guide wire cavity and is connected to the guide wire cavity of the inner guide rod.

50. The apparatus for ablation therapy of the digestive tract according to claim 1 or 48, characterized in that: The connector includes an electrode membrane connector and a deformable connector that is rigid and deformable in the circumferential direction. The electrode membrane connector is parallel to the inner guide rod and connected to the outer end of the electrode membrane. One end of the deformable connector is connected to the electrode membrane connector, and the other end of the deformable connector is connected to the outer guide tube and / or the inner guide rod. During the process of the support frame changing from a contracted working state to an expanded working state, the electrode membrane connector gradually moves away from the inner guide rod. During the process of the support frame changing from an expanded working state to a contracted working state, the electrode membrane connector gradually moves closer to the inner guide rod.

51. The apparatus for ablation therapy of the digestive tract according to claim 50, characterized in that: The deformable connector and the electrode film connector are selected from the following connection structures: pivot connection, fixed connection, slidably connected in the front-back direction, and pivotally and slidably connected, wherein the pivot of the pivotal connection is perpendicular to the inner guide rod; the deformable connector and the outer guide tube and / or inner guide rod are selected from the following connection structures: pivot connection, fixed connection, slidably connected in the front-back direction, and pivotally and slidably connected, wherein the pivot of the pivotal connection is perpendicular to the inner guide rod.

52. The apparatus for ablation therapy of the digestive tract according to claim 50, characterized in that: When the supporting frame changes between the contracted working state and the expanded working state, the distance between the front and rear ends of the deformable connector can be variably set.

53. The apparatus for ablation therapy of the digestive tract according to claim 50, characterized in that: The deformable connector is a rigid elastic sheet with elasticity. When the supporting frame is in a contracted working state, the deformable connector is bent.

54. The apparatus for ablation therapy of the digestive tract according to claim 50, characterized in that: The deformable connector includes multiple sections of rod, with the ends of two adjacent sections pivotally connected to form a chain, an inner guide rod and / or an outer guide rod pivotally connected to an adjacent section of rod, and an electrode film connector pivotally connected to an adjacent section of rod, with the axis of each pivot being spatially perpendicular to the inner guide rod.

55. The apparatus for ablation therapy of the digestive tract according to claim 50, characterized in that: The deformable connector includes multiple sections of rod, which are slidably connected to form a telescopic rod. The electrode film connector is pivotally connected to the end of an adjacent section of rod. The outer guide tube and / or inner guide rod is pivotally connected to an adjacent section of rod, and the axis of each pivot is spatially perpendicular to the inner guide rod.

56. The apparatus for ablation therapy of the digestive tract according to claim 50, characterized in that: The deformable connector includes a deformable connector located at the front of the electrode film connector and a deformable connector located at the rear of the electrode film connector; the rear end of the deformable connector located at the front of the electrode film connector is connected to the front end of the electrode film connector, and the front end of the deformable connector located at the front of the electrode film connector is connected to the inner guide rod; the front end of the deformable connector located at the rear of the electrode film connector is connected to the rear end of the electrode film connector, and the rear end of the deformable connector located at the rear of the electrode film connector is connected to the outer conduit.

57. The apparatus for ablation therapy of the digestive tract according to claim 1 or 48, characterized in that: The inner guide rod and the middle guide tube are fixedly positioned relative to each other in the front-back direction, and the outer guide tube and the middle guide tube are fixedly positioned relative to each other in the front-back direction.

58. The apparatus for ablation therapy of the digestive tract according to claim 1 or 16, characterized in that: The support frame includes an inner support frame and multiple outer support rods connected to the inner support frame. The outer support rods are parallel to the middle guide tube. The multiple outer support rods are distributed in a cylindrical shape around the inner support frame. The inner end of the electrode film is connected to one of the outer support rods.

59. The apparatus for ablation therapy of the digestive tract according to claim 58, characterized in that: The length of the electrode film in the front-to-back direction is greater than or equal to the length of the outer support rod in the front-to-back direction, and the length difference between the two is less than 2 mm.

60. The apparatus for ablation therapy of the digestive tract according to claim 1 or 16, characterized in that: When the supporting frame is in a contracted working state, the electrode membrane is wound around the supporting frame in multiple turns; when the supporting frame is in an expanded working state, the number of turns of the electrode membrane is greater than 1 turn and less than 2 turns.

61. The apparatus for ablation therapy of the digestive tract according to claim 1 or 16, characterized in that: When the distance between the front end of the support frame and the rear end of the support frame changes, the support frame switches between a contracted working state and an expanded working state.

62. The apparatus for ablation therapy of the digestive tract according to claim 1 or 16, characterized in that: The electrode film is clamped to the support frame, so that the innermost ring of the electrode film is always in close contact with the support frame, and the electrode films of adjacent rings are always in close contact with each other.

63. The apparatus for ablation therapy of the digestive tract according to claim 1 or 16, characterized in that: The supporting frame includes an inner supporting frame and multiple outer supporting rods. Each inner supporting rod has a front connecting ring fixed or pivotally connected to its front middle section, forming the front end of the supporting frame. Each inner supporting rod also has a rear connecting ring fixed or pivotally connected to its rear middle section, forming the rear end of the supporting frame. The middle section of each inner supporting rod is fixedly connected to an outer supporting rod. Each outer supporting rod is parallel to the central guide tube, and the multiple outer supporting rods are arranged in a cylindrical, spaced-apart pattern around the inner supporting rods. Each outer supporting rod has a front extension extending forward of the middle section of the inner supporting rod, or / and a rear extension extending backward of the middle section of the inner supporting rod, such that the length of the outer supporting rod in the front-rear direction is greater than the length of the middle section of the inner supporting rod in the front-rear direction. When the supporting frame is in an expanded working state, the inner supporting rods are in an inward-facing arc shape; when the supporting frame is in a contracted working state, the inner supporting rods are approximately straight.

64. The apparatus for ablation therapy of the digestive tract according to claim 63, characterized in that: When the support frame is in the expanded working state, the length of the outer support rod in the front-to-back direction is greater than or equal to the length of the inner support rod in the front-to-back direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

65. The apparatus for ablation therapy of the digestive tract according to claim 1 or 16, characterized in that: The supporting frame includes an inner supporting frame, a middle supporting frame, and multiple outer supporting rods parallel to the central guide tube. The inner supporting frame has a front connecting ring fixed or pivotally connected to its front middle section, forming the front end of the supporting frame. The inner supporting frame also has a rear connecting ring fixed or pivotally connected to its rear middle section, forming the rear end of the supporting frame. The inner supporting frame includes multiple inner supporting rods, and the middle supporting frame includes multiple middle supporting rods. When the supporting frame is in its expanded working state, the inner supporting rods are in an inward-facing arc shape, and the middle supporting rods are in an outward-facing arc shape. Each of the middle supporting rods... The middle sections of the rods are fixedly connected to the middle sections of each inner support rod. When the support frame is in the retracted working state, the middle support rod and the inner support rod are generally straight. The front and rear ends of the middle support rod are respectively connected to the outer support rod. At least one of the two ends of the middle support rod, the front end and the rear end, is slidably connected to the outer support rod in the front-back direction. The multiple outer support rods are distributed in a cylindrical pattern around the middle support rod. The length of the outer support rod in the front-back direction is greater than or equal to the length of the middle support rod in the front-back direction.

66. The apparatus for ablation therapy of the digestive tract according to claim 65, characterized in that: The length of the outer support rod in the front-back direction is greater than or equal to the length of the middle support rod in the front-back direction, and the front end of the middle support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the middle support rod is located in front of or aligned with the rear end of the outer support rod; the length of the outer support rod in the front-back direction is also greater than or equal to the length of the inner support rod in the front-back direction, and the front end of the inner support rod is located behind or aligned with the front end of the outer support rod, and the rear end of the inner support rod is located in front of or aligned with the rear end of the outer support rod.

67. A device for ablation therapy of the digestive tract, characterized in that, include: Slender inner guide rod; A slender central guide tube, which is sleeved on the outside of the inner guide rod; A slender outer conduit is sleeved on the outside of the middle conduit. Among the three components—inner guide rod, middle conduit, and outer conduit—at least one component is defined as a reference component, and at least one other component is defined as a rotating component. The defined rotating component is rotatably arranged relative to the defined reference component. A connector having a first connecting portion and a second connecting portion, wherein the distance between the first connecting portion and the second connecting portion is variably set; An expandable component, having a radially decreasing contraction working state and a radially increasing expansion working state, the expandable component comprising: A support frame is connected to a defined rotating component. The support frame has a deformable component. The deformable component has an elastic force that causes the support frame to tend to expand radially. When the expandable component is in a contracted working state, the support frame is also in a radially shrinking contracted working state. When the expandable component is in an expanding working state, the support frame is also in a radially expanding expanding working state. An electrode membrane is provided with electrodes for receiving electrical signals. The electrode membrane is wound around the outside of the support frame, and its inner end is connected to the support frame. At least one of the defined reference components is connected to a first connection portion of the connector, and the outer end of the electrode membrane is connected to a second connection portion of the connector. When the expandable component is in a contracted working state, the electrode membrane is also in a radially shrinking contracted working state; when the expandable component is in an expanded working state, the electrode membrane is also in a radially expanding expanded working state. If the defined rotating component rotates relative to the defined reference component, the defined rotating component drives the support frame to rotate, and then the inner end of the electrode membrane rotates relative to the outer end of the electrode membrane. The deformable component undergoes elastic deformation so that the support frame abuts against the inner side of the electrode membrane, and the expandable component switches between a contracted working state and an expanded working state.

68. A device for ablation therapy of the digestive tract, characterized in that, include: Slender central duct; A slender outer conduit is sleeved on the outside of the middle conduit. Of the two components, the middle conduit and the outer conduit, one component is defined as a reference component and the other component is defined as a rotating component. The defined rotating component is rotatably arranged relative to the defined reference component. A connector having a first connecting portion and a second connecting portion, wherein the distance between the first connecting portion and the second connecting portion is variably set; An expandable component, having a radially decreasing contraction working state and a radially increasing expansion working state, the expandable component comprising: A support frame is connected to a defined rotating component. The support frame has a deformable component. The deformable component has an elastic force that causes the support frame to tend to expand radially. When the expandable component is in a contracted working state, the support frame is also in a radially shrinking contracted working state. When the expandable component is in an expanding working state, the support frame is also in a radially expanding expanding working state. An electrode membrane is provided with electrodes for receiving electrical signals. The electrode membrane is wound around the outside of the support frame, and its inner end is connected to the support frame. The defined reference component is connected to the first connection portion of the connector, and the outer end of the electrode membrane is connected to the second connection portion of the connector. When the expandable component is in a contracted working state, the electrode membrane is also in a radially shrinking contracted working state; when the expandable component is in an expanded working state, the electrode membrane is also in a radially expanding expanded working state. If the defined rotating component rotates relative to the defined reference component, the defined rotating component drives the support frame to rotate, and then the inner end of the electrode membrane rotates relative to the outer end of the electrode membrane. The deformable component undergoes elastic deformation so that the support frame abuts against the inner side of the electrode membrane, and the expandable component switches between a contracted working state and an expanded working state.

69. The apparatus for ablation therapy of the digestive tract according to claim 67, characterized in that: At least a portion of the expandable component surrounds the outside of the inner guide rod.

70. The apparatus for ablation therapy of the digestive tract according to claim 68, characterized in that: At least a portion of the expandable component surrounds the outer side of the central conduit.

71. The apparatus for ablation therapy of the digestive tract according to claim 67 or 68, characterized in that: The support frame has two ends, one end of the support frame and the other end of the support frame. If the expandable component switches between a contracted working state and an expanded working state, the two ends of the support frame will undergo relative displacement in the front-rear direction.

72. The apparatus for ablation therapy of the digestive tract according to claim 67, 68, or 71, characterized in that, The support frame includes multiple outer support rods and an inner support frame connected to the outer support rods. One of the outer support rods is connected to the inner end of the electrode membrane. The inner support frame is equipped with the deformable component. The outer support rods abut against the inner side of the electrode membrane. If the expandable component is in an expanded working state, the multiple outer support rods surround the outer side of the inner support frame.

73. The apparatus for ablation therapy of the digestive tract according to claim 72, characterized in that, One end of the supporting frame is one end of the inner supporting frame, and the other end of the supporting frame is the other end of the inner supporting frame.

74. The apparatus for ablation therapy of the digestive tract according to claim 72, characterized in that, If the expandable component is in the expansion working state, the multiple external support rods are parallel to the central guide tube.

75. The apparatus for ablation therapy of the digestive tract according to claim 72, characterized in that: The rear middle part of the support frame is pivotally connected to a rear connecting ring. The pivot is perpendicular to the central guide tube, and the rear connecting ring is the rear end of the support frame.

76. The apparatus for ablation therapy of the digestive tract according to claim 72, characterized in that: The front middle part of the support frame is pivotally connected to a front connecting ring. The pivot is perpendicular to the middle guide tube, and the front connecting ring is the front end of the support frame.

77. The apparatus for ablation therapy of the digestive tract according to claim 67 or 68, characterized in that: The supporting frame has one end and the other end. The distance between one end of the support frame and the defined reference component is selected from one of the following arrangements: The configuration can be slidable in the front-back direction and rotatable in the circumferential direction, slidable in the front-back direction and non-rotatable in the circumferential direction, rotatable and positioned in the front-back direction, fixed, or pivotally connected, wherein the pivot of the pivotally connected configuration is perpendicular to the reference component. The other end of the support frame and the defined rotating component are selected from one of the following arrangements: The configuration can be slidable in the front-to-back direction and rotatable in the circumferential direction, slidable in the front-to-back direction and non-rotatable in the circumferential direction, rotatable and positioned in the front-to-back direction, fixed, or pivotally connected, wherein the pivot of the pivotally connected component is perpendicular to the rotating component.

78. The apparatus for ablation therapy of the digestive tract according to claim 67, characterized in that: The connector includes an electrode film connector and a deformable connector that is rigid and deformable in the circumferential direction. The electrode film connector is connected to the deformable connector. The electrode film connector is connected to the outer end of the electrode film and forms a second connection portion of the connector. The deformable connector is also connected to at least one defined reference component to form a first connection portion of the connector. During the process of the expandable component changing from a contracted working state to an expanded working state, the electrode film connector gradually moves away from the inner guide rod. During the process of the expandable component changing from an expanded working state to a contracted working state, the electrode film connector gradually moves closer to the inner guide rod.

79. The apparatus for ablation therapy of the digestive tract according to claim 68, characterized in that: The connector includes an electrode film connector and a deformable connector that is rigid and deformable in the circumferential direction. The electrode film connector is connected to the deformable connector. The electrode film connector is connected to the outer end of the electrode film and forms a second connection portion of the connector. The deformable connector is also connected to the defined reference component to form a first connection portion of the connector. During the process of the expandable component changing from a contracted working state to an expanded working state, the electrode film connector gradually moves away from the central guide tube. During the process of the expandable component changing from an expanded working state to a contracted working state, the electrode film connector gradually moves closer to the central guide tube.

80. The apparatus for ablation therapy of the digestive tract according to claim 78 or 79, characterized in that: The connection between one end of the deformable connector and the electrode film connector is selected from one of the following connection structures: pivot connection, fixed connection, slidable connection, and pivotal and slidable connection, wherein the pivot is perpendicular to the central conduit. The connection between the other end of the deformable connector and the defined reference component is selected from one of the following connection structures: pivot connection, fixed connection, slidable connection, and pivotal and slidable connection, wherein the pivot is perpendicular to the central guide tube.

81. The apparatus for ablation therapy of the digestive tract according to claim 78 or 79, characterized in that: When the expandable component changes between a contracted working state and an expanded working state, the distance between the two ends of the deformable connector can be variably set.

82. The apparatus for ablation therapy of the digestive tract according to claim 81, characterized in that: The deformable connector is a rigid component that can deform. When the expandable component is in a contracted working state, the deformable connector is in a bent shape.

83. The apparatus for ablation therapy of the digestive tract according to claim 81, characterized in that: The deformable connector includes multiple sections of rod, which are pivotally connected and / or slidably connected to each other, wherein the pivot of the pivotal connection is perpendicular to the central guide tube.

84. The apparatus for ablation therapy of the digestive tract according to claim 78 or 79, characterized in that: The electrode membrane connector is parallel to the central conduit.

85. The apparatus for ablation therapy of the digestive tract according to claim 67, characterized in that: The outer guide tube and inner guide rod are both defined as reference components. The inner guide rod and the outer guide tube are arranged in a circumferential manner and cannot be rotated relative to each other. The middle guide tube is defined as a rotating component. The middle guide tube is rotatably arranged relative to the outer guide tube and the inner guide rod. The support frame is connected to the middle guide tube. The first connecting part of the connector is connected to the outer guide tube or the inner guide rod.

86. The apparatus for ablation therapy of the digestive tract according to claim 78 or 85, characterized in that: The first connecting portion of the connector is connected to the inner guide rod and the outer conduit, respectively, and the connector is configured to restrict the outer end of the electrode membrane from rotating circumferentially relative to the inner guide rod and the outer conduit.

87. The apparatus for ablation therapy of the digestive tract according to claim 85, characterized in that: The outer guide tube and the inner guide rod are either fixedly arranged or slidably arranged in the front-to-back direction.

88. The apparatus for ablation therapy of the digestive tract according to claim 85, characterized in that, One end of the support frame is the front end of the support frame, and the other end of the support frame is the rear end of the support frame. The front end of the support frame is sleeved on the outside of the inner guide rod, and the rear end of the support frame is connected to the middle guide tube.

89. The apparatus for ablation therapy of the digestive tract according to claim 78, characterized in that: One end of the deformable connector is connected to the outer guide tube or the inner guide rod.

90. The apparatus for ablation therapy of the digestive tract according to claim 78, characterized in that: The electrode film connector is parallel to the inner guide rod.

91. The apparatus for ablation therapy of the digestive tract according to claim 79, characterized in that: One end of the deformable connector is connected to the outer conduit.

92. The apparatus for ablation therapy of the digestive tract according to claim 79, characterized in that: The electrode membrane connector is parallel to the central conduit.

93. The apparatus for ablation therapy of the digestive tract according to claim 67, characterized in that: The inner guide rod is a tubular body with a guide wire cavity, and the tubular body is defined as the inner tube.

94. The apparatus for ablation therapy of the digestive tract according to claim 67 or 68, characterized in that: The electrode membrane is spirally wound around the outside of the supporting frame. During the transition from the contracted working state to the expanded working state, the diameter of the outermost electrode membrane gradually increases and the total number of turns of the electrode membrane gradually decreases; conversely, during the transition from the expanded working state to the contracted working state, the diameter of the outermost electrode membrane gradually decreases and the total number of turns of the electrode membrane gradually increases.

95. The apparatus for ablation therapy of the digestive tract according to claim 67 or 68, characterized in that: The support frame includes multiple outer support rods and an inner support frame connected to the outer support rods. Each outer support rod and its corresponding inner support frame form a linkage mechanism. The inner support frame includes multiple first connecting rods, multiple second connecting rods, a front connecting ring at the front, and a rear connecting ring at the rear. At least one linkage mechanism is an X-type linkage mechanism. In the X-type linkage mechanism, the rear end of the first connecting rod is fixedly connected to the rear of the outer support rod, and the front end of the first connecting rod is fixedly connected to the front connecting ring. The front end of the second connecting rod is fixedly connected to the... The front part of the outer support rod is fixedly connected, and the rear end of the second link is fixedly connected to the rear connecting ring. At least one of the four parts of the first link, the first link, the second link, and the second link constitutes the deformable component, or all four parts of the first link, the first link, the second link, and the second link constitute the deformable component. When the expandable component is in the expansion working state, the first link and the second link intersect and there is no rotating pivot for connection at the intersection point.

96. The apparatus for ablation therapy of the digestive tract according to claim 95, characterized in that: All of the aforementioned linkage mechanisms are X-type linkage mechanisms, with the rear end of the first linkage fixedly connected to the rear end of the outer support rod, and the front end of the second linkage fixedly connected to the front end of the outer support rod.

97. The apparatus for ablation therapy of the digestive tract according to claim 95, characterized in that: The width of both ends of the outer support rod is greater than the width of the rear end of the first connecting rod connected to it and the width of the front end of the second connecting rod connected to it.

98. The apparatus for ablation therapy of the digestive tract according to claim 95, characterized in that: The width of the rear portion of the first link is smaller than the width of the middle portion of the first link, and the width of the front portion of the first link is smaller than the width of the middle portion of the first link; and / or, The width of the rear part of the second link is smaller than the width of the middle part of the second link, and the width of the front part of the second link is smaller than the width of the middle part of the second link.

99. The apparatus for ablation therapy of the digestive tract according to claim 95, characterized in that: The width of the rear part of the outer support rod is greater than the width of the middle part of the outer support rod, and the width of the front part of the outer support rod is greater than the width of the middle part of the outer support rod. Through holes for fixing the inner end of the electrode film are respectively opened at both ends of the outer support rod.

100. The apparatus for ablation therapy of the digestive tract according to claim 67 or 68, characterized in that: It also includes an actuator connected to the rotating component, the actuator being used to drive the rotating component to rotate relative to the reference component.

101. The apparatus for ablation therapy of the digestive tract according to claim 1 or 16, characterized in that: The connection between the rear end of the support frame and the central conduit is configured to restrict the rear end of the support frame from rotating circumferentially relative to the central conduit.

102. The apparatus for ablation therapy of the digestive tract according to claim 1 or 16, characterized in that: The connection between the outer end of the electrode membrane and the outer conduit is configured to restrict the outer end of the electrode membrane from rotating circumferentially relative to the outer conduit.

103. The apparatus for ablation therapy of the digestive tract according to claim 67 or 68, characterized in that: The connection between the support frame and the defined rotating component is configured to restrict the circumferential rotation of the support frame relative to the defined rotating component.

104. The apparatus for ablation therapy of the digestive tract according to claims 67 and 68, characterized in that: The connector is configured to restrict the outer end of the electrode membrane from rotating circumferentially relative to the defined reference component.

105. A support frame for an apparatus for ablation therapy of the digestive tract, characterized in that: The supporting frame has a radially contracting working state and a radially expanding working state. The supporting frame includes multiple outer support rods and an inner supporting frame connected to the outer support rods. The inner supporting frame includes multiple first connecting rods, multiple second connecting rods, a front connecting ring at the front, and a rear connecting ring at the rear. The multiple linkage mechanisms of the supporting frame include at least one X-shaped linkage mechanism. In the X-shaped linkage mechanism, the rear end of the first connecting rod is fixedly connected to the rear of the outer support rod, the front end of the first connecting rod is fixedly connected to the front connecting ring, and the front end of the second connecting rod is fixedly connected to the outer support rod. The front part of the strut is fixedly connected, and the rear end of the second link is fixedly connected to the rear connecting ring. At least one of the four parts—the front part of the first link, the rear part of the first link, the front part of the second link, and the rear part of the second link—constitutes a deformable component, or all four parts of the first link, the rear part of the first link, the front part of the second link, and the rear part of the second link constitute deformable components. When the support frame is in the expanded working state, the first link and the second link intersect and there is no pivot for connection at the intersection. The deformable component has an elastic force that causes the support frame to tend to increase radially.

106. The supporting frame of the device for ablation treatment of the digestive tract according to claim 105, characterized in that: All of the aforementioned linkage mechanisms are X-type linkage mechanisms, with the rear end of the first linkage fixedly connected to the rear end of the outer support rod, and the front end of the second linkage fixedly connected to the front end of the outer support rod.

107. The supporting frame of the device for ablation treatment of the digestive tract according to claim 105, characterized in that: The width of both ends of the outer support rod is greater than the width of the rear end of the first connecting rod connected to it and the width of the front end of the second connecting rod connected to it.

108. The supporting frame of the device for ablation treatment of the digestive tract according to claim 105, characterized in that: The width of the rear portion of the first link is smaller than the width of the middle portion of the first link, and the width of the front portion of the first link is smaller than the width of the middle portion of the first link; and / or, The width of the rear part of the second link is smaller than the width of the middle part of the second link, and the width of the front part of the second link is smaller than the width of the middle part of the second link.

109. The supporting frame of the device for ablation therapy of the digestive tract according to claim 105, characterized in that: The width of the rear part of the outer support rod is greater than the width of the middle part of the outer support rod, and the width of the front part of the outer support rod is greater than the width of the middle part of the outer support rod. Through holes for fixing the inner end of the electrode film are respectively opened at both ends of the outer support rod.

110. A method for preparing a support frame for an ablation treatment device for the digestive tract as described in claim 105, characterized in that, The preparation steps include the following: S1. The pipe is cut through to form the front connecting ring, the rear connecting ring, and multiple sets of first connecting rods, outer support rods and second connecting rods disposed between the front connecting ring and the rear connecting ring. The two ends of the outer support rod are respectively adjacent to and spaced apart from the front connecting ring and the rear connecting ring. S2. The cut pipe is heated and shaped in the expansion working state, so that the deformable component has the elastic force in the contraction working state after the shaped support frame is formed.

111. The method for preparing the support frame of the device for ablation therapy of the digestive tract according to claim 110, characterized in that: After step S2, the support frame is converted to a retractable working state, restoring the shape of the cut pipe.

112. A system for ablation therapy of the digestive tract, characterized in that, It includes the apparatus for ablation treatment of the digestive tract as described in any one of claims 1-104, and further includes: A signal generator configured to generate an electrical signal for generating electric field energy, the signal generator being electrically connected to the electrodes.

113. A device for ablation therapy of the human duodenum, characterized in that, It includes an apparatus for ablation treatment of the digestive tract as described in any one of claims 1-104.

114. The use of the device for ablation treatment of the human duodenum as described in claim 113 in the treatment of type 2 diabetes.

115. The use of the device for ablation treatment of the human duodenum as described in claim 113 in the treatment of obesity.

116. The use of the device for ablation treatment of the human duodenum as described in claim 113 in the treatment of non-alcoholic fatty liver disease.

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