A biological tissue welding device, control system and method

Abstract

The application relates to a biological tissue welding device, a control system and a method, a welding clamp of the biological tissue welding device is provided with a first electrode and a second electrode, biological tissues to be anastomosed are placed in the first electrode and the second electrode, the first electrode and the second electrode are driven by a transmission rod and a push rod, and can be controllably close to or away from each other under the power driving of a driving machine, so that the biological tissues to be anastomosed are conveniently clamped. Through the setting of a circuit channel, wires in the machine body pass through and are electrically connected with the first electrode and the second electrode, and installation space of a transmission assembly is provided. The welding clamp obtains power and power from the machine body, and biological tissue welding is facilitated.

Description

Technical Field

[0001] This application belongs to the field of medical device technology, and in particular relates to a biological tissue welding device, control system and method. Background Technology

[0002] In neurosurgical craniotomy, tight dural anastomosis is a crucial step in preventing serious complications such as postoperative cerebrospinal fluid leakage and intracranial infection. Currently, the mainstream clinical methods for dural closure are manual suturing and titanium clip (or staple) anastomosis. Manual suturing is a mature technique with a wide range of applications, but it is cumbersome, requires a high level of surgical skill, and the presence of sutures as foreign bodies may trigger inflammatory reactions or become sources of infection. While titanium clip (or staple) anastomosis simplifies the procedure and improves efficiency, it still carries risks such as permanent retention of metallic foreign bodies, postoperative imaging interference, and leakage due to poor adhesion to thin and tough tissue. Neither method achieves true seamless and biological healing.

[0003] Radiofrequency tissue welding is an emerging seamless anastomosis technology that utilizes the thermal effect of high-frequency current to achieve the fusion of biological tissues. The basic principle of this technology is that when radiofrequency current flows through the tissue, it generates heat, causing the macromolecular structures such as collagen in the tissue to denature and cross-link. With the assistance of external pressure, the interfaces of adjacent tissues are fused together.

[0004] However, applying radiofrequency welding technology to the thin, tough, poorly vascularized, and highly sensitive dura mater also presents several intractable challenges. Currently, radiofrequency anastomosis technology is primarily developed and optimized for solid organs such as the liver and kidneys. Its energy output mode, electrode design, and temperature control strategies are typically based on the characteristics of these tissues. Directly applying such instruments to dura mater anastomosis can easily lead to excessive thermal damage, charring, or even burn-through due to imprecise temperature control, not only failing to achieve effective anastomosis but also potentially causing severe secondary damage. More importantly, the length and shape of dura mater incisions vary greatly depending on surgical needs and individual anatomical differences. Existing radiofrequency anastomosis instruments typically have fixed welding tips, lacking the ability to flexibly adapt to incisions of different sizes and shapes. This significantly limits the clinical feasibility and universality of this technology in the delicate procedure of dura mater anastomosis. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to provide a biological tissue welding device, control system and method to solve one or more of the above-mentioned problems when radio frequency welding technology is applied to dura mater anastomosis.

[0006] The technical solution adopted by this invention to solve its technical problem is:

[0007] A biological tissue welding device, comprising:

[0008] A welding clamp includes a first electrode, a second electrode, a transmission rod, and a push rod; a cavity is provided between the first electrode and the second electrode for inserting biological tissue to be anastomosed; the push rod is connected to the first electrode and the second electrode through the transmission rod, and the push rod can move the first electrode and the second electrode closer to each other or further apart when it moves;

[0009] body;

[0010] The drive unit is installed inside the housing;

[0011] A connecting rod is used to connect the welding clamp to the machine body; the connecting rod is provided with a circuit channel, through which wires inside the machine body pass and are electrically connected to the first electrode and the second electrode.

[0012] A transmission assembly is installed within the circuit channel. The transmission assembly is connected to the drive motor and the push rod. When the drive motor is activated, it can drive the push rod to move through the transmission assembly.

[0013] Preferably, in the biological tissue welding device of the present invention, the connecting rod and the welding clamp are connected at a preset angle, wherein the preset angle is between 90 degrees and 180 degrees.

[0014] Preferably, in the biological tissue welding apparatus of the present invention, the transmission component includes a flexible transmission shaft, the two ends of which are respectively connected to the output shaft of the drive motor and the push rod;

[0015] The welding clamp includes a pole cavity cover, and the push rod is threadedly connected to the pole cavity cover. The push rod can extend and retract along its axial direction when it rotates.

[0016] Preferably, in the biological tissue welding device of the present invention, the inner wall of the insulating shell of the welding clamp is formed with a guide groove, the extension direction of the guide groove is perpendicular to the axial direction of the push rod, the first electrode and the second electrode are both connected to the guide groove and can move along the guide groove; one end of the transmission rod is hinged to the push rod, and the other end is hinged to the first electrode or the second electrode.

[0017] Preferably, in the biological tissue welding apparatus of the present invention, the connecting rod is detachably connected to the body via an adjustment interface; and the transmission assembly is detachably connected to the output shaft of the drive motor.

[0018] Preferably, in the biological tissue welding apparatus of the present invention, the welding clamp further includes a component integrated into the first electrode or the second electrode:

[0019] A pressure sensor is used to sense the pressure generated when the first electrode and the second electrode clamp biological tissue;

[0020] A temperature sensor is used to sense the temperature when the first electrode and the second electrode are welded together to form biological tissue.

[0021] Preferably, the biological tissue welding device of the present invention further includes: a display screen and control buttons installed on the outside of the device body, wherein the display screen is used to display the status information of the biological tissue welding device, and the control buttons are used to control the drive motor to rotate forward, reverse, or stop.

[0022] A biological tissue welding control system includes the aforementioned biological tissue welding device, and further includes a radio frequency energy generator, wherein the radio frequency energy generator is connected to a first electrode and a second electrode via wires to generate radio frequency current on the first electrode and the second electrode.

[0023] Preferably, the biological tissue welding control system of the present invention further includes a human-machine interface, which is installed on the radio frequency energy generator and is used to control and display the operating status of the radio frequency energy generator.

[0024] A biological tissue welding method, employing the aforementioned biological tissue welding control system, includes the following steps:

[0025] S1. Select and install welding clips of appropriate specifications according to the required length of the dura mater incision.

[0026] S2, Adjust the position and angle of the machine body so that the welding clamp is aligned with the edge of the dura mater to be fitted;

[0027] S3, start the drive motor to drive the welding clamp to close and clamp the dura mater tissue with a set pressure;

[0028] S4, activate the radio frequency energy generator to allow radio frequency current to flow through the first and second electrodes and through the clamped dura mater tissue.

[0029] S5, based on the temperature data fed back by the temperature sensor and / or the tissue impedance data monitored by the radio frequency energy generator, control the output of radio frequency energy so that the dura mater tissue can achieve collagen fusion at the interface.

[0030] S6, when the preset matching endpoint index is reached, stop the radio frequency energy output and control the welding clamp to open.

[0031] The beneficial effects of this invention are as follows: In this embodiment of the biological tissue welding device, the welding clamp is equipped with a first electrode and a second electrode for inserting the biological tissue to be anastomosed. The first and second electrodes are driven by a transmission rod and a push rod, and can be controllably moved closer or further apart under the power of a drive motor, facilitating the clamping of the biological tissue to be anastomosed. The circuit channel allows wires inside the device to pass through and electrically connect to the first and second electrodes, and provides installation space for the transmission components. This allows the welding clamp to obtain power from the device body, facilitating the implementation of biological tissue welding. Attached Figure Description

[0032] The technical solution of this application will be further described below with reference to the accompanying drawings and embodiments.

[0033] Figure 1 This is a schematic diagram of the biological tissue welding control system structure in this embodiment;

[0034] Figure 2 This is a schematic diagram of the biological tissue welding device in this embodiment;

[0035] Figure 3 This is a schematic diagram of the cross-sectional structure of the welding clamp in this embodiment;

[0036] Figure 4 yes Figure 3 Enlarged view of a section of the welding clamp.

[0037] The attached figures are labeled as follows:

[0038] 1. Welding clamp; 2. Adjustment interface; 3. Connecting rod; 4. Display screen; 5. Body; 6. Drive motor; 7. Radio frequency energy generator; 8. Circuit channel; 9. Control button; 10. Human-machine interface; 11. Foot switch; 12. Pole cavity cover; 13. Push rod; 14. Transmission rod; 15. Pressure sensor; 16. First electrode; 17. Insulating shell; 18. Cavity; 19. Temperature sensor; 20. Electrode cavity cover; 21. Second electrode; 22. Guide groove. Detailed Implementation

[0039] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other.

[0040] In the description of this application, it should be understood that the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicating orientation or positional relationships based on the orientation or positional relationships shown in the accompanying drawings, are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as limiting the scope of protection of this application. Furthermore, the terms "first," "second," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, features defined with "first," "second," etc., may explicitly or implicitly include one or more of that feature. In the description of this invention, unless otherwise stated, "a plurality of" means two or more.

[0041] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection between two components. Those skilled in the art will understand the specific meaning of the above terms in this application based on the specific circumstances.

[0042] In the accompanying drawings, for clarity, the length, area, volume, gap dimensions, and relative dimensions of components, as well as the included angles and relative positional relationships between components, may be exaggerated. The same reference numerals denote the same elements throughout the drawings.

[0043] The technical solution of this application will now be described in detail with reference to the accompanying drawings and embodiments.

[0044] This embodiment provides a biological tissue welding device, such as... Figures 1-3 As shown, it includes: welding clamp 1, machine body 5, drive motor 6, connecting rod 3 and transmission assembly.

[0045] The welding clamp 1 includes a first electrode 16, a second electrode 21, a transmission rod 14, and a push rod 13; there is a cavity 18 between the first electrode 16 and the second electrode 21 for inserting biological tissue to be anastomosed; the push rod 13 is connected to the first electrode 16 and the second electrode 21 through the transmission rod 14, and when the push rod 13 moves, it can drive the first electrode 16 and the second electrode 21 to move closer or further apart.

[0046] The drive unit 6 (which may be a motor) is installed inside the body 5.

[0047] The connecting rod 3 is used to connect the welding clamp 1 to the machine body 5; the connecting rod 3 is provided with a circuit channel 8, through which the wires in the machine body 5 pass and are electrically connected to the first electrode 16 and the second electrode 21.

[0048] The transmission assembly is installed within the circuit channel 8. The transmission assembly is connected to the drive motor 6 and the push rod 13. When the drive motor 6 is activated, it can move the push rod 13 via the transmission assembly. It should be noted that the space for the wire wiring and the space for the transmission assembly are different, and therefore do not interfere with each other.

[0049] In this embodiment of the biological tissue welding apparatus, the welding clamp 1 is equipped with a first electrode 16 and a second electrode 21 for inserting the biological tissue to be anastomosed. The first electrode 16 and the second electrode 21 are driven by a transmission rod 14 and a push rod 13, and can be controllably moved closer or further apart under the power drive of the drive motor 6, facilitating the clamping of the biological tissue to be anastomosed. The circuit channel 8 allows wires inside the machine body 5 to pass through and electrically connect to the first electrode 16 and the second electrode 21, and provides installation space for the transmission components. This allows the welding clamp 1 to obtain power from the machine body 5, facilitating the biological tissue welding process.

[0050] The bio-tissue welding device of this embodiment operates on the following principle: the regions where the first electrode 16 and the second electrode 21 are located form an anastomosis surface for transmitting radio frequency energy. During the transmission of radio frequency current, an electric field is generated between the first electrode 16 and the second electrode 21 due to the potential difference. Since the bio-tissue contains positive and negative ions, these ions reciprocate at high speed between the first electrode 16 and the second electrode 21 under the action of the high-frequency electric field, thereby generating heat within the bio-tissue. This heat can break the hydrogen bonds between collagen molecules in the bio-tissue, causing the collagen molecules to lose their interaction forces and become free. Combined with the external pressure of the welding clamp, this achieves the coagulation of the bio-tissue, laying the foundation for the realization of ion surgery.

[0051] In an optional embodiment, the connecting rod 3 is connected to the welding clamp 1 at a preset angle, which is between 90 and 180 degrees. This design makes it easier to adjust the angle and position of the welding clamp 1 during surgery, conforming to ergonomic principles.

[0052] In an optional embodiment, the transmission assembly includes a flexible transmission shaft, with its two ends connected to the output shaft of the drive motor 6 and the push rod 13, respectively. The welding clamp 1 includes a pole cavity cover 12, and the push rod 13 is threadedly connected to the pole cavity cover 12. The push rod 13 can extend and retract along its axial direction when rotated. This design utilizes a flexible transmission shaft, allowing the connecting rod 3 and the welding clamp 1 to be connected at a preset angle while simultaneously transmitting the power output from the drive motor 6 to the push rod 13 normally. The flexible transmission shaft can be made of a flexible material and bendable, or it can be formed by connecting multiple rigid shafts, with universal joints between the rigid shafts, effectively making it bendable.

[0053] In an alternative embodiment, such as Figure 3 , Figure 4 As shown, the inner wall of the insulating outer shell 17 of the welding clamp 1 is formed with a guide groove 22. The extension direction of the guide groove 22 is perpendicular to the axial direction of the push rod 13. The first electrode 16 and the second electrode 21 are both connected to the guide groove 22 and can move along the guide groove 22. One end of the transmission rod 14 is hinged to the push rod 13, and the other end is hinged to the first electrode 16 or the second electrode 21. In this scheme, as... Figure 4 As shown, to enhance the transmission stability of the transmission rods 14, the number of transmission rods 14 can be four or more, and they can be symmetrically distributed along both sides of the push rod 13. Through the hinged structure between the push rod 13 and the transmission rod 14, the linear motion of the push rod 13 is converted into the rotational motion of the transmission rod 14, and then into the linear motion of the first electrode 16 and the second electrode 21 moving closer or further apart. It can be understood that the movement of the first electrode 16 and the second electrode 21 closer or further apart depends on whether the drive motor 6 rotates forward or backward.

[0054] In an alternative embodiment, such as Figure 1 , Figure 2 As shown, the connecting rod 3 is detachably connected to the machine body 5 via the adjustment interface 2; the transmission component is detachably connected to the output shaft of the drive motor 6. In this embodiment, a modular design concept is adopted, and the detachable structure of the connecting rod 3 and the machine body 5 allows for flexible replacement of the welding clip 1. For example, based on different patient needs and the actual length of the intraoperative dura mater incision, 3 to 5 specifications of welding clip 1 can be designed. When using this device, the most suitable specification of welding clip 1 is selected according to the specific patient's condition, and then assembled onto the machine body 5 via the adjustment interface 2. This solves the bottleneck that a single instrument cannot adapt to different surgical needs, improving the instrument's versatility and surgical efficiency.

[0055] The adjustment interface 2 can be a bushing. After the connecting rod 3 is connected to the machine body 5, the transmission component is connected to the output shaft of the drive motor 6. The adjustment interface 2 is sleeved on the connecting rod 3 on one side and screwed to the machine body 5 on the other. The connecting rod 3 can be configured to have rotational freedom so as to rotate around the axis of the machine body 5.

[0056] In an alternative embodiment, such as Figure 3 As shown, the welding clamp 1 also includes a pressure sensor 15 and a temperature sensor 19 integrated into the first electrode 16 or the second electrode 21. The pressure sensor 15 (which may be a thin-film type) is used to sense the pressure generated when the first electrode 16 and the second electrode 21 clamp the biological tissue; the temperature sensor 19 is used to sense the temperature when the first electrode 16 and the second electrode 21 are welding the biological tissue. By sensing the pressure and temperature, it is easy to adaptively control the clamping force and output power of the first electrode 16 and the second electrode 21. This helps to stably apply the uniform pressure and energy required for anastomosis and reduce human error.

[0057] In an alternative embodiment, such as Figure 1 , Figure 2 As shown, the biological tissue welding device also includes a display screen 4 and control buttons 9 mounted on the outside of the device body 5. The display screen 4 is used to display the status information of the biological tissue welding device, and the control buttons 9 are used to control the drive motor 6 to rotate forward, reverse, or stop. The display screen 4 allows operators to easily know the various operating parameters of the device in real time for adjustment, and the control buttons 9 are located on the side of the device body 5 for easy operation during surgery, increasing ease of use.

[0058] In an alternative embodiment, such as Figure 1 , Figure 2 As shown, the clamp head of welding clamp 1 has a large arc-shaped structure, which is conducive to conforming to the curve of the human head.

[0059] In an optional embodiment, to achieve multi-parameter sensing within a limited space, this embodiment employs a multi-layer flexible circuit board process to conformally integrate the pressure sensor 15, temperature sensor 19, and electrode array (composed of the first electrode 16 and the second electrode 21) onto the mating surface, and connects them to the main control circuit through a unified micro-interface. When the actual clamping pressure detected by the pressure sensor 15 reaches a preset threshold, this status information is transmitted in real time and displayed on the display screen 4, providing the operator with intuitive confirmation feedback.

[0060] This embodiment provides a biological tissue welding control system, such as Figure 1As shown, the biological tissue welding device includes a radio frequency (RF) energy generator 7. The RF energy generator 7 is connected to a first electrode 16 and a second electrode 21 via wires to generate an RF current between the first electrode 16 and the second electrode 21. The RF energy generator 7 outputs high-power energy to the welding clamp 1, heating the tissue collagen to achieve fusion welding. The RF current generated by the RF energy generator 7 flows through the following path: first electrode 16 — biological tissue — second electrode 21.

[0061] Conventional high-frequency electrosurgical units tend to generate significant Joule heat within biological tissues. This heat diffuses outwards from the treated area, resulting in severe thermal damage to the tissues caused by ordinary high-frequency currents. Radiofrequency tissue welding offers significant advantages in controlling thermal damage. It employs a low-temperature, bipolar operating mode, precisely confining heat between the two electrodes, thereby greatly reducing the extent of thermal damage and virtually eliminating tissue carbonization.

[0062] The operator can interact with the machine via the display screen 4 to set initial parameters such as RF output power, duration, and duty cycle. During the welding process, the control circuit inside the RF energy generator 7 collects the current and voltage signals flowing through the biological tissue in real time through the first electrode 16 and the second electrode 21, and calculates the instantaneous power and tissue impedance accordingly. Simultaneously, the temperature sensor 19 integrated into the welding clamp anastomosis surface monitors the biological tissue temperature in real time and transmits the temperature signal to the control circuit of the RF energy generator 7 via the circuit channel 8 inside the connecting rod 3.

[0063] In an optional embodiment, the biological tissue welding control system is equipped with an alarm component. When the radio frequency energy generator is activated, radio frequency energy is applied to the biological tissue. When the temperature approaches a preset threshold, the alarm component issues a corresponding alarm. When the threshold is reached, the control unit's temperature monitoring program stops the output of radio frequency energy.

[0064] In an alternative embodiment, such as Figure 1 As shown, the biological tissue welding control system also includes a human-machine interface 10, which is installed on the radio frequency energy generator 7 and used to control and display the operating status of the radio frequency energy generator 7. The control circuit inside the radio frequency energy generator 7 detects parameters such as current, voltage, power, impedance, and temperature of the biological tissue in real time during the process, and simultaneously adjusts the various output parameters in real time, displaying these parameters on the display screen 4 and the human-machine interface 10.

[0065] This embodiment provides an intelligent control system for biological tissue welding. The intelligent control system further includes a control unit that receives signals from a temperature sensor 19 and a pressure sensor 15, and works in conjunction with a drive motor 6 and a radio frequency energy generator 7. The control unit can also automatically preset or recommend optimized energy and pressure parameters based on the specifications of the connected welding clamp 1 (obtained through a built-in identification circuit in the welding clamp assembly). During the anastomosis process, the control unit dynamically adjusts the output power of the radio frequency energy based on real-time temperature feedback, forming a closed-loop temperature control circuit to ensure that the dura mater tissue is heated to the optimal collagen denaturation and fusion temperature range (typically 60°C~80°C), while strictly preventing excessive temperature from causing thermal damage. This control system can independently achieve precise control of the welding process described in this application.

[0066] This embodiment provides a biological tissue welding method, employing the aforementioned biological tissue welding control system, including the following steps:

[0067] S1. Select and install a welding clip 1 of appropriate specifications according to the required length of the dura mater incision.

[0068] S2, adjust the position and angle of the machine body 5 so that the welding clamp 1 is aligned with the edge of the dura mater to be fitted;

[0069] S3, start the drive motor 6 to drive the welding clamp 1 to close and clamp the dura mater tissue with a set pressure;

[0070] S4, activate the radio frequency energy generator 7, so that the radio frequency current flows through the first electrode 16 and the second electrode 21 through the clamped dura mater tissue.

[0071] S5, based on the temperature data fed back by the temperature sensor 19 and / or the tissue impedance data monitored by the radio frequency energy generator 7, control the output of radio frequency energy so that the dura mater tissue can achieve collagen fusion at the interface.

[0072] S6, when the preset matching endpoint index is reached, stop the radio frequency energy output and control the welding clamp 1 to open.

[0073] In an optional embodiment, in step S3, pressure sensor 15 collects pressure data of the biological tissue being tweezed by welding clamp 1 and transmits it to the display screen 4. Relevant parameters are adjusted, and control button 9 is pressed again to control the drive motor 6 to continuously adjust the positions of the first electrode 16 and the second electrode 21 until the pressure data fed back by pressure sensor 15 reaches the set pressure value. In step S4, the radio frequency energy generator 7 outputs radio frequency energy to the first electrode 16 and the second electrode 21 according to a preset radio frequency output power to weld the tweezed biological tissue. In step S5, temperature sensor 19 collects temperature data of the biological tissue at the welding point and transmits it to the display screen 4. The display screen 4 receives the temperature data and determines whether it is within a preset range. If not, the human-machine interface 10 on the radio frequency energy generator controls the radio frequency energy generator 7 to reduce or increase its radio frequency output power until the temperature data fed back by temperature sensor 19 reaches the preset range.

[0074] In an optional embodiment, when an external power supply is connected to the system, the control unit initializes its various functional parameters and enters a standby state. The operator sets parameters such as the operating status and speed of the drive motor 6, the clamping pressure of the welding clamp 1, the RF energy output power, the action time, and the duty cycle via the display screen 4 and human-machine interface 10 on the machine body 5. The operator performs the above controls using the control buttons 9 on the machine body 5.

[0075] In an alternative embodiment, such as Figure 1 As shown, the radio frequency energy generator 7 is powered on by a foot switch 11. Figure 3 As shown, the electrode cavity cover 20 and the pole cavity cover 12 respectively seal the two ends of the welding clamp 1 body to protect the internal electrodes.

[0076] This embodiment provides a method for intelligent welding of biological tissues, employing the aforementioned intelligent control system for biological tissue welding, and includes the following steps:

[0077] S1. Select and install a welding clip 1 of appropriate specifications according to the required length of the dura mater incision.

[0078] S2, adjust the position and angle of the machine body 5 so that the welding clamp 1 is aligned with the edge of the dura mater to be fitted;

[0079] S3, start the drive motor 6 to drive the welding clamp 1 to close, and the intelligent control system automatically clamps the dura mater tissue with the set pressure;

[0080] S4, activate the radio frequency energy generator 7, so that the radio frequency current flows through the first electrode 16 and the second electrode 21 through the clamped dura mater tissue.

[0081] S5, based on the temperature data fed back by the temperature sensor 19 and / or the tissue impedance data monitored by the radio frequency energy generator 7, the intelligent control system automatically controls the output of radio frequency energy so that the dura mater tissue can achieve collagen fusion at the interface.

[0082] S6, when the preset matching endpoint index is reached (such as specific energy accumulation, impedance change or time), the intelligent control system automatically stops the radio frequency energy output and controls the welding clamp 1 to open.

[0083] The biological tissue welding method of this embodiment first clamps the dura mater tissue with a set pressure during the operation, and then monitors the temperature data and / or the tissue impedance data monitored by the radio frequency energy generator 7 in real time to control the output of radio frequency energy. This allows for the parameterized determination of the pressure and radio frequency energy power required for welding, effectively reducing the probability of thermal damage to biological tissue.

[0084] The biological tissue welding control device and system of this embodiment can achieve sutureless / staple-free in-situ biological healing. Compared with traditional anastomosis techniques such as needle and suture suturing, staple anastomosis, and titanium clip closure, this application utilizes radiofrequency energy to fuse the dura mater's own collagen, achieving in-situ welding without any exogenous implants (such as sutures, staples, or clips). This avoids the risk of inflammation and infection caused by foreign body residue, facilitates the formation of continuous tissue connections, and promotes postoperative tissue healing.

[0085] The system enhances surgical adaptability and operability: the modular, multi-specification welding clip assembly (welding clip 1 and connecting rod 3) allows a single system to flexibly handle dural incisions of various sizes, improving instrument versatility. Motor drive and intelligent control simplify surgeon operations, lower the technical barrier, and ensure more uniform and stable application of anastomotic pressure and energy, contributing to improved consistency and reliability of anastomotic quality.

[0086] It achieves intelligent and standardized operation: Through the control system, experience-dependent manual operation is transformed into a standardized process with controllable parameters, reducing human error and improving the safety and repeatability of the surgery.

[0087] The biological tissue welding method of this embodiment significantly reduces the risk of thermal damage: through the structure and method of integrating a temperature sensor 19 into the anastomosis surface and closed-loop feedback control, precise temperature management of the welding process is achieved, strictly limiting the thermal effect to the minimum range required for tissue fusion, and effectively protecting the fragile dura mater and the underlying brain tissue.

[0088] Based on the above-described preferred embodiments according to this application, and through the foregoing description, those skilled in the art can make various changes and modifications without departing from the technical concept of this application. The technical scope of this application is not limited to the contents of the specification, but must be determined according to the scope of the claims.

Claims

1. A biological tissue welding device, characterized in that, include: A welding clamp (1) includes a first electrode (16), a second electrode (21), a transmission rod (14), and a push rod (13); there is a cavity (18) between the first electrode (16) and the second electrode (21) for inserting biological tissue to be anastomosed; the push rod (13) is connected to the first electrode (16) and the second electrode (21) through the transmission rod (14), and the push rod (13) can move the first electrode (16) and the second electrode (21) closer to or further away from each other when it moves; fuselage (5); The drive unit (6) is installed inside the body (5); A connecting rod (3) is used to connect the welding clamp (1) to the machine body (5); the connecting rod (3) is provided with a circuit channel (8), and the circuit channel (8) allows the wires in the machine body (5) to pass through and be electrically connected to the first electrode (16) and the second electrode (21); The transmission assembly is installed in the circuit channel (8). The transmission assembly is connected to the drive machine (6) and the push rod (13). When the drive machine (6) is driven, it can drive the push rod (13) to move through the transmission assembly.

2. The biological tissue welding apparatus according to claim 1, characterized in that, The connecting rod (3) is connected to the welding clamp (1) at a preset angle, which is between 90 degrees and 180 degrees.

3. The biological tissue welding apparatus according to claim 2, characterized in that, The transmission assembly includes a flexible transmission shaft, the two ends of which are respectively connected to the output shaft of the drive motor (6) and the push rod (13). The welding clamp (1) includes a pole cavity cover (12), and the push rod (13) is threadedly connected to the pole cavity cover (12). The push rod (13) can extend and retract along its axial direction when it rotates.

4. The biological tissue welding apparatus according to claim 3, characterized in that, The inner wall of the insulating shell (17) of the welding clamp (1) is formed with a guide groove (22). The extension direction of the guide groove (22) is perpendicular to the axial direction of the push rod (13). The first electrode (16) and the second electrode (21) are both connected to the guide groove (22) and can move along the guide groove (22). One end of the transmission rod (14) is hinged to the push rod (13), and the other end is hinged to the first electrode (16) or the second electrode (21).

5. The biological tissue welding apparatus according to any one of claims 1-4, characterized in that, The connecting rod (3) is detachably connected to the body (5) via the adjustment interface (2); the transmission assembly is detachably connected to the output shaft of the drive motor (6).

6. The biological tissue welding apparatus according to any one of claims 1-4, characterized in that, The welding clamp (1) further includes an element integrated into the first electrode (16) or the second electrode (21): A pressure sensor (15) is used to sense the pressure generated when the first electrode (16) and the second electrode (21) clamp biological tissue; Temperature sensor (19) is used to sense the temperature when the first electrode (16) and the second electrode (21) are welded together to form biological tissue.

7. The biological tissue welding apparatus according to any one of claims 1-4, characterized in that, The biological tissue welding device further includes a display screen (4) and control buttons (9) installed on the outside of the body (5). The display screen (4) is used to display the status information of the biological tissue welding device, and the control buttons (9) are used to control the drive motor (6) to rotate forward, reverse, or stop.

8. A biological tissue welding control system, characterized in that, The biological tissue welding apparatus as described in any one of claims 1-7 further includes a radio frequency energy generator (7) connected to a first electrode (16) and a second electrode (21) via wires to generate radio frequency currents in the first electrode (16) and the second electrode (21).

9. The biological tissue welding control system according to claim 8, characterized in that, The biological tissue welding control system also includes a human-machine interface (10), which is installed on the radio frequency energy generator (7) and is used to control and display the operating status of the radio frequency energy generator (7).

10. A method for welding biological tissues, characterized in that, The biological tissue welding control system as described in claim 8 or 9 is employed. Includes the following steps: S1. Select and install welding clips of appropriate specifications according to the required length of the dura mater incision (1). S2, adjust the position and angle of the body (5) so that the welding clamp (1) is aligned with the edge of the dura mater to be fitted; S3, start the drive (6) to drive the welding clamp (1) to close and clamp the dura mater tissue with a set pressure; S4, start the radio frequency energy generator (7) so that the radio frequency current flows through the first electrode (16) and the second electrode (21) through the clamped dura mater tissue; S5, based on the temperature data fed back by the temperature sensor (19) and / or the tissue impedance data monitored by the radio frequency energy generator (7), control the output of radio frequency energy so that the dura mater tissue can achieve collagen fusion at the interface; S6, when the preset matching endpoint index is reached, stop the radio frequency energy output and control the welding clamp (1) to open.

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