A tea-flower extract oil composition for sensitive skin with pain and its preparation method and application
Patent Information
- Application Number
- CN202611144778.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-07-30
- Publication Date
- 2026-09-25
AI Technical Summary
一方面,部分产品依赖单一抗炎成分(如甘草酸二钾、泛醇),仅能暂时性抑制炎症因子释放,无法修复受损的皮肤屏障,导致泛红、刺痛症状反复出现;另一方面,现有产品中常用的植物成分多为水溶性提取物,脂溶性差,难以穿透受损角质层到达作用靶点,且缺乏对神经末梢敏感的针对性舒缓成分,无法有效缓解痛觉型敏感肌的灼热、刺痛感
本发明所述组合物通过精准调控绿茶油与樱花油、香蜂花籽油、有兰花油构成的花萃油的优选量比,实现四种组分的协同增效,针对性解决痛觉型敏感肌泛红、炎症及屏障脆弱问题。其中,绿茶油的茶多酚与花萃油活性成分形成抗炎网络,樱花油的黄酮类物质强化修红作用,香蜂花籽油的不饱和脂肪酸修复皮肤屏障以降低痛觉敏感性,玉兰花油的多糖成分则提升肌肤耐受度,四者互补增效,相较于单一组分或非优选比例,该组合能更快速抑制炎症因子释放、缓解泛红灼热,同时增强皮肤屏障功能,减少敏感复发,为痛觉型敏感肌提供更精准、高效的修红抗炎功效。
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Figure CN122805514A_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of cosmetic technology, and in particular relates to a tea-flower extract oil composition for redness reduction and anti-inflammation specifically developed for pain-sensitive skin, as well as its preparation method and application. Background Technology
[0002] With increasing environmental pollutants, heightened stress, and improper skincare practices, the proportion of people with sensitive skin is rising year by year. Among them, pain-sensitive skin, characterized by both pronounced redness and intense pain, has become a challenging issue in the skincare field. The core pathological mechanism of pain-sensitive skin is as follows: severely impaired skin barrier function and imbalanced lipid content in the stratum corneum, making it easier for external stimuli to penetrate the epidermis; simultaneously, abnormally sensitive nerve endings in the skin lead to excessive release of inflammatory factors (such as IL-6 and TNF-α), ultimately causing symptoms such as redness, burning sensation, stinging, and itching. Furthermore, this type of skin exhibits extremely poor tolerance to external stimuli such as temperature changes, chemical skincare products, and ultraviolet radiation, severely impacting the user's quality of life.
[0003] Existing anti-inflammatory and redness-reducing products are mostly designed for "generally sensitive skin," failing to precisely address the three core needs of pain-sensitive skin: "barrier repair, inflammation suppression, and pain relief." On one hand, some products rely on single anti-inflammatory ingredients (such as dipotassium glycyrrhizate and panthenol), which can only temporarily inhibit the release of inflammatory factors and cannot repair the damaged skin barrier, leading to recurring redness and stinging symptoms. On the other hand, the plant ingredients commonly used in existing products are mostly water-soluble extracts with poor lipid solubility, making it difficult to penetrate the damaged stratum corneum to reach the target site. Furthermore, they lack targeted soothing ingredients for sensitive nerve endings, failing to effectively relieve the burning and stinging sensations of pain-sensitive skin. Furthermore, improving pain-sensitive skin requires a scientific synergy of "anti-inflammatory ingredients + barrier repair ingredients + nerve-soothing ingredients," but existing technologies have obvious shortcomings in their combination: either the ingredients are chaotic and disorganized, with multiple anti-inflammatory ingredients being blindly stacked (such as adding curcumin and resveratrol at the same time), which not only easily leads to ingredient antagonism but may also increase the risk of skin irritation; or there is a lack of precise screening and combination of active oils such as flower extracts. If existing products contain flower extracts, they are mostly single varieties (such as only containing rose oil or chamomile oil), which cannot enhance the effect through the complementary effects of different flower extracts.
[0004] Therefore, existing redness-repairing and anti-inflammatory products cannot accurately match the physiological characteristics of pain-sensitive skin, and have problems such as weak ingredient targeting, lack of synergistic effect, and imbalance between safety and effectiveness. There is an urgent need to develop a composition that is specifically designed for pain-sensitive skin, with scientifically synergistic ingredients, and has both redness-repairing, anti-inflammatory and pain-relieving effects. Summary of the Invention
[0005] The purpose of this invention is to overcome the shortcomings of the prior art and provide a tea-flower extract oil composition specifically designed for pain-sensitive skin to repair redness and reduce inflammation, as well as its preparation method and application. The composition formulation is specifically optimized to precisely match the triple pathological characteristics of pain-sensitive skin: active inflammation, fragile barrier, and sensitive nerves, achieving synergistic effects of repairing redness, reducing inflammation, and relieving pain.
[0006] To achieve the above objectives, the technical solution adopted by the present invention includes: In a first aspect, the present invention provides a tea-flower extract oil composition specifically designed for pain-sensitive skin to reduce redness and inflammation, the composition comprising the following components in parts by weight: 1-5 parts green tea oil and 1-6 parts flower extract oil; the flower extract oil includes cherry blossom oil, lemon balm seed oil and magnolia flower oil.
[0007] Preferably, the flower extract oil comprises the following components in parts by weight: 0.3-2 parts cherry blossom oil, 0.3-2 parts lemon balm seed oil, and 0.4-2 parts magnolia flower oil.
[0008] Green tea oil is extracted from the fresh leaves of plants in the Theaceae family through cold pressing. Its core active ingredients are tea polyphenols (especially epigallocatechin gallate ester EGCG), squalene, and unsaturated fatty acids (linoleic acid and linolenic acid). EGCG effectively reduces the release of pro-inflammatory factors and eliminates reactive oxygen species in the skin, alleviating redness and inflammation at their source. It also regulates the TRPV1 channels in the sensory nerve endings of the skin, reducing nerve sensitivity to stimuli and directly relieving the burning and stinging sensations of pain-sensitive skin. Squalene is highly similar to the lipid structure of the skin itself, quickly replenishing the stratum corneum lipids and filling barrier gaps. Linoleic acid and linolenic acid promote the proliferation and differentiation of keratinocytes, enhancing the density of the stratum corneum, reducing the penetration of external stimuli, and fundamentally reducing the probability of inflammation triggering.
[0009] The floral extract oil is a blend of cherry blossom oil, lemon balm seed oil, and magnolia oil in a specific ratio. The three ingredients complement each other, focusing on "redness reduction, anti-inflammation, and skin barrier repair" to create a precise synergistic effect. Cherry blossom oil is rich in active ingredients such as cherry blossom glycosides, flavonoids, and unsaturated fatty acids (oleic acid and palmitic acid). Cherry blossom glycosides can inhibit capillary dilation, reduce red blood cell extravasation in inflammatory states, and quickly improve skin redness. Flavonoids can scavenge ROS, reducing oxidative damage to sensitive skin from UV rays and pollutants. Unsaturated fatty acids can help replenish skin lipids, forming a lipid complement with the squalene in green tea oil, enhancing the skin barrier's water-locking ability. The core active ingredients in lemon balm seed oil include citral, flavonoids, and polyphenols. Citral can inhibit the transcriptional expression of key pro-inflammatory factors such as TNF-α and IL-6, significantly inhibiting chronic inflammation in sensitive skin. Apigenin can block the recruitment of inflammatory cells, reduce inflammatory infiltration, and relieve skin swelling and burning, thus achieving a powerful anti-inflammatory effect. Magnolia flower oil is rich in orchid polysaccharides, flavonoids, phytosterols, and other components. Orchid polysaccharides can promote the synthesis of filaggrin by keratinocytes, enhancing the integrity and elasticity of the stratum corneum. Phytosterols can regulate skin lipid metabolism, repair damaged lipid bilayer structure, enhance the barrier's resistance to external stimuli, and reduce inflammation recurrence. Flavonoids can inhibit the continuous activation of inflammatory pathways and regulate the activity of skin immune cells, avoiding excessive immune response and achieving the dual effects of anti-inflammatory and stabilizing effects.
[0010] This invention combines green tea oil with a specific ratio of flower extract oil to form a triple synergistic mechanism of inflammation suppression, barrier repair, and nerve soothing, thereby effectively meeting the dual needs of pain-sensitive skin for "rapid redness and inflammation repair" and "long-lasting barrier repair," and solving the technical limitations of limited effects of single ingredients and poor synergy of conventional combinations.
[0011] Preferably, the composition comprises the following components in parts by weight: 2-3 parts green tea oil and 3-6 parts flower extract oil.
[0012] Preferably, the flower extract oil comprises the following components in parts by weight: 1-2 parts cherry blossom oil, 0.5-2 parts lemon balm seed oil, and 1-2 parts magnolia flower oil.
[0013] Preferably, the composition comprises the following components in parts by weight: 3 parts green tea oil and 6 parts flower extract oil.
[0014] Preferably, the flower extract oil comprises the following components in parts by weight: 2 parts cherry blossom oil, 2 parts lemon balm seed oil, and 2 parts magnolia flower oil.
[0015] Experimental research has revealed that when the green tea oil and flower extract oil in the composition are combined in the above-defined optimal amounts, the components work together to exert excellent synergistic effects, thereby maximizing the anti-inflammatory, redness-reducing, and barrier-repairing effects of the composition.
[0016] Preferably, the cherry blossom oil, lemon balm seed oil, and magnolia flower oil are all obtained using a supercritical CO2 extraction process; the specific extraction conditions for the cherry blossom oil are: extraction at 38-42℃ and 28-32MPa pressure for 3.5-4.5h; the specific extraction conditions for the lemon balm seed oil are: extraction at 38-42℃ and 28-32MPa pressure for 5.5-6.5h; and the specific extraction conditions for the magnolia flower oil are: extraction at 38-42℃ and 28-32MPa pressure for 4.5-5.5h.
[0017] This invention employs the aforementioned preferred supercritical CO2 extraction process to prepare cherry blossom oil, lemon balm seed oil, and magnolia flower oil. This process effectively ensures the full release of active ingredients while avoiding their decomposition and oxidation due to high temperatures, thereby further enhancing the redness-reducing and anti-inflammatory effects of the composition. Furthermore, the skin barrier of pain-sensitive skin is fragile and has extremely low tolerance to chemical solvents. Residual solvents can directly trigger allergic reactions such as stinging and redness. The supercritical CO2 extraction process leaves no organic solvent residue, effectively reducing the risk of irritation for sensitive skin and meeting the compliance requirements for gentle and non-irritating products for sensitive skin.
[0018] Secondly, the present invention provides the use of the described composition in cosmetics.
[0019] Preferably, the cosmetics include liquids, serums, creams, sunscreens, masks, and makeup.
[0020] Thirdly, the present invention provides an essence with redness-reducing and anti-inflammatory effects, the essence comprising the aforementioned composition.
[0021] Preferably, the essence further includes at least one of a moisturizer, an emulsifier, a stabilizer, a thickener, and a preservative; The humectant includes at least one of glycerin, sodium hyaluronate, and butylene glycol; and / or, the emulsifier includes polyglycerol-3 diisostearate; and / or, the thickener includes carbomer; and / or, the preservative includes phenoxyethanol; and / or, the stabilizer includes tocopheryl acetate.
[0022] Fourthly, the present invention provides a method for preparing the aforementioned essence, comprising the following steps: S1. Mix the composition with emulsifier and stabilizer, and heat to 55-60℃ until completely dissolved to obtain the oil phase; S2. Add the humectant and thickener to water, heat and stir until completely dissolved to obtain the aqueous phase; S3. Add the aqueous phase to the oil phase, then add the preservative, homogenize at 1800-2200 rpm for 10-20 min, cool down, and control the viscosity at 2000-3000 mPa・s to obtain the essence.
[0023] Compared with the prior art, the beneficial effects of the present invention are as follows: The composition of this invention achieves synergistic effects by precisely controlling the optimal ratio of green tea oil to flower extracts consisting of cherry blossom oil, lemon balm seed oil, and magnolia oil. This specifically addresses the redness, inflammation, and fragile skin barrier issues associated with pain-sensitive skin. Specifically, the tea polyphenols in green tea oil form an anti-inflammatory network with the active ingredients in the flower extracts; the flavonoids in cherry blossom oil enhance the redness-reducing effect; the unsaturated fatty acids in lemon balm seed oil repair the skin barrier to reduce pain sensitivity; and the polysaccharides in magnolia oil improve skin tolerance. These four components complement each other, resulting in a more rapid inhibition of inflammatory factor release and relief of redness and burning compared to single components or non-optimal ratios. Simultaneously, this combination strengthens the skin barrier function, reduces sensitivity recurrence, and provides more precise and efficient redness-reducing and anti-inflammatory effects for pain-sensitive skin. Attached Figure Description
[0024] Figure 1 The images show the appearance of the compositions prepared in Examples 1 and 3. Detailed Implementation
[0025] To better illustrate the objectives, technical solutions, and advantages of this invention, the invention will be further described below with reference to specific embodiments. Those skilled in the art should understand that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
[0026] Unless otherwise specified, all raw materials used in the following examples and comparative examples are commercially available general-purpose materials.
[0027] The Longjing green tea oil described in the following examples and comparative examples was purchased from the Tea Research Institute of the Chinese Academy of Agricultural Sciences. Cherry blossoms, lemon balm seeds, and magnolia flowers were collected from the Lingnan Flower Market in Guangzhou.
[0028] Examples 1-6 Examples 1-6 provide a tea-flower extract oil composition specifically formulated for pain-sensitive skin to reduce redness and inflammation. The formulation of the composition is shown in Table 2. The preparation method of the composition includes the following steps: (1) Preparation of cherry blossom oil, lemon balm seed oil and magnolia flower oil S1. Initial raw material screening and pretreatment: Fresh cherry blossoms, mature lemon balm seeds, and fresh magnolia blossoms free from mold and insect damage were selected and quickly rinsed twice with deionized water, then drained. They were then pulverized into 1-2mm flocculent particles using a high-speed grinder and placed in a vacuum drying oven at 40℃ and -0.08MPa for 2 hours, controlling the final moisture content to ≤5%. Lemon balm seeds, due to their hardness, were pulverized into 80-100 mesh powder using an ultrafine grinder. Magnolia blossom buds were pulverized into 2-3mm blocks, vacuum dried at 38℃ and -0.08MPa for 1.5 hours, with a moisture content ≤5%. S2. Raw material loading: The three pretreated raw materials were separately loaded into a supercritical extraction vessel (5L volume), with a loading amount of 1.5kg for each (corresponding to a scale-up ratio of 100g raw material), and the loading density was controlled at 0.4g / cm³. 3 .
[0029] S3, Supercritical CO2 Extraction Process: A dynamic extraction mode is adopted, with continuous circulation of CO2 fluid to improve dissolution efficiency. The three extraction raw materials are poured into the extraction vessel respectively. The core process parameters of the three are completely consistent. Only the extraction time is finely adjusted according to the characteristics of the raw materials to ensure that the product ratio is uniform. The specific parameter settings are shown in Table 1 below.
[0030] Table 1. Setting of supercritical CO2 extraction process parameters S4. System Leak Detection and Preheating: Close all valves in the extraction vessel and separation vessel, introduce CO2 into the system to 5MPa, maintain the pressure for 30 minutes, and check for leaks at all interfaces; turn on the heating system of the extraction vessel and separation vessel, raise the temperatures of E1, S1, and S2 to 40℃, 35℃, and 25℃ respectively, and maintain the temperature for 30 minutes to ensure temperature stability. S5, CO2 supercriticality and extraction start-up: Open the outlet valve of the CO2 storage tank, pressurize the CO2 to 30MPa through the high-pressure pump, and after passing through the heat exchanger and being heated to the same temperature as the extraction vessel at 40℃, continuously introduce the CO2 into the extraction vessel E1 at a flow rate of 20L / h; the CO2 fully contacts the raw material in E1, dissolves the oil components, and flows out from the top of E1 into the separation vessel S1, where the pressure drops to 10MPa. At this time, most of the oil precipitates out due to the decrease in solubility and is collected in the oil receiving pan at the bottom of S1; S6. Deep Separation and CO2 Recovery: The incompletely separated CO2-grease mixture flows out from the top of S1 and enters the separation vessel S2. The pressure is reduced to 5MPa and the temperature is 25℃, and the residual grease is completely separated and collected in the oil receiving pan at the bottom of S2. The CO2 after grease separation is liquefied at 15℃ by a cooler and returned to the CO2 storage tank to achieve recycling (recovery rate ≥90%). S7. Oil collection and preliminary purification: After extraction, the high-pressure pump is turned off and the CO2 supply is stopped. When the system pressure drops to atmospheric pressure, the oil drain valves of S1 and S2 are opened to collect the oils in the two separation vessels and combine them into crude oil. The crude oil is then transferred to a centrifuge tube and centrifuged for 15 minutes at 8000 rpm / min and 25°C. After centrifugation, the upper layer is the clarified oil and the lower layer is the residue. The lower layer of raw material residue is removed to obtain refined cherry blossom oil, lemon balm seed oil and magnolia flower oil.
[0031] (2) Mix the prepared cherry blossom oil, lemon balm seed oil, magnolia oil and green tea oil evenly to obtain the composition.
[0032] Table 2. Redness-reducing and anti-inflammatory compositions described in Examples 1-6 (parts by weight) Comparative Examples 1-8 Comparative Examples 1-8 provide a composition, the formulation of which is shown in Table 3. The preparation method of the composition is the same as that of Example 4, except for the formulation.
[0033] Table 3 shows the formulations (parts by weight) of the compositions described in Comparative Examples 1-8. Comparative Example 9 This comparative example provides a composition that differs from Example 4 only in that an equal amount of white tea oil (silver needle extract oil) is used to replace Longjing green tea oil, while the remaining components and amounts are the same as in Example 4.
[0034] Comparative Example 10 This comparative example provides a composition that differs from Example 4 only in that an equal amount of crabapple oil is used to replace cherry blossom oil, while the other components and amounts are the same as in Example 4.
[0035] Application Examples 1-6 Application Examples 1-6 provide a serum with redness-reducing and anti-inflammatory effects, wherein the active ingredients in the serum correspond sequentially to the redness-reducing and anti-inflammatory compositions described in Examples 1-6. The formulation of the serum is shown in Table 4 (total weight parts: 100 parts). The preparation method of the serum includes the following steps: S1. Oil phase preparation: Add the anti-inflammatory composition, polyglycerol-3 diisostearate, and tocopheryl acetate to the oil phase pot, heat to 55-60℃ at 300 rpm / min, and keep stirring for 15 minutes until all components are completely dissolved and mixed evenly, with no visible particles or stratification. Keep warm for later use. S2. Aqueous phase preparation: Add glycerol and panthenol to deionized water at 400 rpm and stir for 5 minutes until dissolved. Then slowly add sodium hyaluronate and carbomer and heat to 55-60℃. Continue stirring until completely dissolved and keep warm for later use. S3. Emulsification and homogenization: Under constant temperature and stirring at 500 rpm / min, slowly add the aqueous phase from step S2 to the oil phase and preservative from step S1, homogenize at 2000 rpm / min for 15 minutes, replenish the water evaporated due to heating with deionized water to ensure the mass is 100 parts, continue stirring for 10 minutes until completely homogeneous, cool down, control the viscosity at 2500 mPa・s, and after passing the test, let stand to defoam to obtain the essence.
[0036] Table 4 shows the formulation (parts by weight) of the serums described in Application Examples 1-6. Application Comparative Examples 1-8 Comparative Examples 1-8 provide a serum in which the active ingredients correspond sequentially to the compositions described in Comparative Examples 1-8. The formulation of the serum is shown in Table 5 (total parts by weight: 100 parts). The preparation method of the serum is the same as that of the application examples, except for the formulation.
[0037] Table 5 shows the formulation (parts by weight) of the serums described in Comparative Examples 1-8. Application Comparison Example 9 This application provides an essence that differs from Application Example 4 only in that an equal amount of white tea oil (silver needle extract oil) is used to replace Longjing green tea oil, while the other components and amounts are the same as in Application Example 4.
[0038] Application Comparison Example 10 This application provides a serum that differs from Application Example 4 only in that an equal amount of crabapple oil is used to replace cherry blossom oil, while the other components and amounts are the same as in Application Example 4.
[0039] Example of effect 1 This example uses the compositions described in Examples 1-6 as test samples, and performs multiple stability tests on them. The four stability test schemes are as follows: 1. Stability at room temperature: 25±2℃, sealed and protected from light for 30 days; 2. High temperature stability: 45±2℃, constant temperature and sealed storage for 30 days; 3. Low temperature stability: -15±2℃, constant temperature and sealed for 30 days, then take it out and bring it to room temperature for observation; 4. Stability under alternating high and low temperatures: 45℃ for 12h ↔ -15℃ for 12h constitutes one cycle, and 5 cycles are completed continuously.
[0040] Acceptance criteria: A uniform and transparent appearance, without layering, turbidity, precipitated oil particles, discoloration, off-odor, or flocculation sedimentation indicates stability and acceptance; the presence of layering, floating oil, sedimentation, yellowing or browning, or rancid odor indicates poor stability. Specific test results are shown in Table 6.
[0041] Table 6 Test results show that the composition obtained by compounding four active components—Longjing green tea oil, cherry blossom oil, lemon balm seed oil, and magnolia oil—exhibits excellent temperature resistance, capable of resisting system damage caused by temperature fluctuations. The components exhibit good compatibility, effectively avoiding the defects of single oil components being susceptible to temperature-induced precipitation, stratification, and floating oil formation. The compounding synergistically enhances the interfacial stability of the oil system, effectively maintaining system homogeneity and stability over a wide temperature range.
[0042] Example 2 In cases of pain-sensitive muscle inflammation, the activation of macrophages and the release of TNF-α, IL-6, and IL-1β are central. LPS (lipopolysaccharide) can induce macrophages to mimic an inflammatory state. The anti-inflammatory activity of the composition was assessed by detecting the secretion of inflammatory factors. This efficacy example uses the compositions prepared in Examples 1-6 and Comparative Examples 1-10 as test samples for in vitro anti-inflammatory testing. The specific test methods are as follows: (1) Materials 1. Cells: Mouse macrophages RAW264.7; 2. Reagents: LPS (1 μg / mL, inflammation inducer), test sample (sample test concentration is 1%), positive control (1% nicotinamide), ELISA kit (detection of TNF-α, IL-6, IL-1β).
[0043] (2) Test steps: 1. Cell seeding: RAW264.7 cells were seeded at a rate of 5 × 10⁻⁶ cells / year. 4 Inoculate 1 cell / well into a 96-well plate and incubate at 37°C and 5% CO2 for 24 hours until adherence; 2. Grouping: The sample group was divided into blank group (cell-free + culture medium), model group (cells + LPS + culture medium), sample group (cells + LPS + test sample), and positive control group (cells + LPS + positive control). Each group had 6 replicates. 3. Inflammation induction and intervention: Except for the blank group, LPS was added to the other groups to induce inflammation, and corresponding samples / positive controls were added at the same time, and culture was continued for 24 hours; 4. Index detection: Collect the supernatant and follow the ELISA kit instructions to detect the absorbance (OD value) of TNF-α, IL-6, and IL-1β, and calculate the concentration. 5. Result Calculation: Inflammatory factor inhibition rate (%) = (Model group concentration - Sample group concentration) / (Model group concentration - Blank group concentration) × 100% The specific test results are shown in Table 7.
[0044] Table 7 Table 7 shows that the composition prepared by the technical solution of the present invention can effectively inhibit the release of inflammatory factors, thereby exerting a good anti-inflammatory effect. In particular, the composition described in Example 4 has the best anti-inflammatory effect. However, when the total amount of cherry blossom oil, lemon balm seed oil and magnolia oil in the flower extract oils described in Examples 5-6 is the same as that in Example 4, but the proportion deviates slightly from the preferred range of the present invention, the anti-inflammatory effect is slightly reduced compared with the examples. This indicates that the precise limitation of the internal component ratio of the flower extract oil in the present invention is the key prerequisite for ensuring the anti-inflammatory effect.
[0045] When Comparative Examples 1-5 lacked any one or two of the flower extracts—cherry blossom oil, lemon balm seed oil, and magnolia oil—and when Comparative Example 6 lacked green tea oil, although the total amount of the composition was the same as in Example 4, its anti-inflammatory efficacy was significantly reduced compared to Example 4. This indicates that the four plant oil active components of the present invention can exert a synergistic effect, thereby significantly improving the anti-inflammatory effect of the composition; all four components are indispensable. When the ratio of green tea oil to flower extracts in Comparative Examples 7-8 exceeded the limits of the present invention, the anti-inflammatory efficacy of the composition also decreased to a certain extent. This indicates that the active components of the present invention can only form precise complementary effects and maximize synergistic efficacy when the ratio is within the limited range; once the ratio is unbalanced, the synergistic effect between the components will weaken or even be lost, directly leading to a decline in overall efficacy. When the selected components of this invention were replaced with plant oils with similar effects in Comparative Examples 9-10, the anti-inflammatory effect of the composition also decreased compared with the examples. This proves that the four components selected in this invention are not simply an additive effect. Their chemical structure, active sites and other characteristics are highly compatible with the anti-inflammatory mechanism. Even if the substitute components have similar effects, they cannot form a precise synergy with other components.
[0046] Example 3 This efficacy example uses the serums described in Application Examples 1-6 and Comparative Examples 1-10 as test samples to test their redness-reducing effects on the human body. The specific test methods are as follows: (1) Subject selection: 160 subjects aged 22-55 years with pain-sensitive facial skin were selected. Subjects were characterized by stinging, burning, and persistent redness after exposure to cold or heat, skin care products, or wind. Subjects with facial inflammatory skin diseases (eczema, acne), recent use of hormones / anti-inflammatory drugs, or allergies to the sample ingredients were excluded. Subjects were randomly divided into 16 groups of 10 each.
[0047] (2) Testing Procedure: Before using the sample, each group of subjects sat quietly for 30 minutes in a constant temperature and humidity environment (21±1℃, humidity 50±10%). The baseline (T0) of facial redness a* was photographed and measured using a VISIA instrument. After starting use, the corresponding serum was applied to the entire face after cleansing in the morning and evening, 0.5mL each time, for 28 consecutive days. Follow-up visits were conducted on day 7 (T7) and day 28 (T28), and the facial redness a* value was remeasured after sitting quietly in the same environment for 30 minutes. The formula for calculating the redness improvement rate is as follows: Improvement rate (%) = (T0 - Tn) / T0 × 100% (n = 7d, 28d) The specific test results are shown in Table 8.
[0048] Table 8 Table 8 shows that the serum product containing the anti-inflammatory and redness-reducing composition prepared according to the technical solution of this invention significantly improved the reduction of redness after application, indicating that it can effectively alleviate irritation-induced redness, thereby effectively meeting the needs of pain-sensitive skin for redness reduction and anti-inflammation. In contrast, the comparative products, due to the absence of specific active ingredients in this invention or deviation from the scientific proportions of key components, showed a significant decrease in the redness reduction rate and a substantial weakening of the anti-inflammatory and redness-reducing effects.
[0049] Finally, it should be noted that the above embodiments are used to illustrate the technical solutions of the present invention and not to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the essence and scope of the technical solutions of the present invention.
Claims
1. A tea-flower extract oil composition specifically formulated for pain-sensitive sensitive skin to reduce redness and inflammation, characterized in that, The composition comprises the following components in parts by weight: 1-5 parts green tea oil and 1-6 parts flower extract oil; the flower extract oil includes cherry blossom oil, lemon balm seed oil and magnolia flower oil.
2. The composition according to claim 1, characterized in that, The composition comprises the following components in parts by weight: 2-3 parts green tea oil and 3-6 parts flower extract oil.
3. The composition according to claim 1, characterized in that, The flower extract oil comprises the following components in parts by weight: 0.3-2 parts cherry blossom oil, 0.3-2 parts lemon balm seed oil, and 0.4-2 parts magnolia flower oil.
4. The composition according to claim 3, characterized in that, The flower extract oil comprises the following components in parts by weight: 1-2 parts cherry blossom oil, 0.5-2 parts lemon balm seed oil, and 1-2 parts magnolia flower oil.
5. The composition according to claim 1, characterized in that, The cherry blossom oil, lemon balm seed oil and magnolia flower oil were all prepared using supercritical CO2 extraction technology. The specific extraction conditions for the cherry blossom oil are: extraction at 38-42℃ and 28-32MPa pressure for 3.5-4.5 hours; The specific extraction conditions for the lemon balm seed oil are: extraction at 38-42℃ and 28-32MPa pressure for 5.5-6.5 hours; The specific extraction conditions for the magnolia flower oil are: extraction at 38-42℃ and 28-32MPa pressure for 4.5-5.5h.
6. The use of the composition according to any one of claims 1-5 in cosmetics.
7. An essence with redness-reducing and anti-inflammatory effects, characterized in that, The serum comprises the composition according to any one of claims 1-5.
8. The essence as described in claim 7, characterized in that, The serum also includes at least one of the following: moisturizer, emulsifier, stabilizer, thickener, and preservative; The humectant includes at least one of glycerin, sodium hyaluronate, and butylene glycol; and / or, the emulsifier includes polyglycerol-3 diisostearate; and / or, the thickener includes carbomer; and / or, the preservative includes phenoxyethanol; and / or, the stabilizer includes tocopheryl acetate.
9. The method for preparing the essence as described in claim 8, characterized in that, Includes the following steps: S1. Stir and mix the composition with emulsifier and stabilizer, and heat to 55-60℃ until completely dissolved to obtain the oil phase; S2. Add the humectant and thickener to water, heat and stir until completely dissolved to obtain the aqueous phase; S3. Add the aqueous phase to the oil phase, then add the preservative, homogenize at 1800-2200 rpm for 10-20 min, cool down, and control the viscosity at 2000-3000 mPa・s to obtain the essence.