A moisturizing, mosquito-repelling and itching-relieving balm and a preparation method thereof

Abstract

The present application relates to the technical field of traditional Chinese medicine balm and its preparation, and discloses a moisturizing, mosquito-repelling and itching-relieving balm and a preparation method thereof, which is prepared from natural materials such as agarwood, sandalwood and Szechuan lovage root by a carbon dioxide supercritical extraction combined with a molecular distillation process, and innovatively uses the balm matrix component as an entrainer for supercritical extraction, thereby significantly improving the extraction yield of active components in the raw materials. The prepared balm has a long-lasting fragrance, excellent moisturizing performance, itching-relieving effect on mosquito bites, and certain mosquito-repelling effect, and is safe, environmentally friendly, solvent-free, and widely applicable. The present application realizes the modernization of Buddhist bathing, and provides a new technical path for the application of natural plant components in the personal care field.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine balm and its preparation technology, specifically to a moisturizing, mosquito-repellent, and antipruritic balm and its preparation method. Background Technology

[0002] Solid perfumes are a classic type of solid aromatherapy product. Their small size, portability, hygiene, and wide applicability have made them a popular choice in modern personal care. Traditional solid perfumes primarily use natural plant fragrances as their core ingredients, offering basic benefits such as refreshing aroma, soothing the mind and body, and nourishing the skin. They effectively improve dry skin, freshen body odor, and relieve stress, meeting consumers' daily skincare and aromatherapy needs. Among these, plant-based solid perfumes that combine moisturizing, mosquito repellent, and anti-itch properties specifically address issues like mosquito bites, dry and itchy skin, and environmental insect infestations in summer. Compared to single-function perfumes, they offer greater versatility, suitable for use at home, outdoors, and while traveling, and possess broad market prospects and high development value.

[0003] To fully leverage the efficacy of natural plant ingredients and enhance the quality of perfume products, existing technologies focus on two core areas for improvement: increasing the efficiency of extracting effective plant components and optimizing the longevity of the fragrance. Regarding the extraction of effective plant components, current mainstream processes primarily include organic solvent extraction and steam distillation, supplemented by traditional physical extraction methods such as pressing and soaking to initially extract active plant components and improve raw material utilization. Organic solvent extraction can efficiently enrich aromatic and functional components from plants, while steam distillation, with its environmentally friendly and residue-free advantages, is suitable for the large-scale extraction of natural fragrances. In terms of extending fragrance duration and optimizing performance, existing technologies optimize perfume base formulations to suit the loading system of plant essential oils and active ingredients. Simultaneously, they optimize extraction and base mixing processes to improve the compatibility of active ingredients with the perfume base, reducing the rapid volatilization of active ingredients, thereby extending the fragrance duration and enhancing the product's effectiveness.

[0004] However, existing perfume preparation processes and product technologies still have many significant shortcomings, making it difficult to meet the production and use needs of high-quality, multi-functional perfumes. Firstly, plant ingredient extraction processes have obvious limitations. Traditional pressing and soaking methods have low extraction efficiency, insufficient dissolution of active ingredients, and extremely low raw material utilization. Organic solvent extraction methods pose a risk of solvent residue, resulting in poor product safety and insufficient environmental friendliness, which does not align with the development trend of green care products. While steam distillation is environmentally friendly and safe, its low extraction efficiency easily leads to the loss of large amounts of heat-sensitive and volatile active ingredients, severely diminishing the efficacy of the raw materials. Secondly, existing technologies struggle to balance the demands of efficient extraction and long-lasting fragrance. Plant active ingredients extracted using conventional processes are highly volatile and have poor stability when combined with the perfume matrix, resulting in short-lasting fragrance and rapid efficacy decay. Finally, existing preparation processes are cumbersome, with plant extraction and matrix mixing carried out independently in separate steps, resulting in low process integration and low production efficiency. Furthermore, traditional balms have limited functionality, offering only a soothing aroma and failing to simultaneously provide multiple benefits such as moisturizing, mosquito repellency, and itch relief. Traditional Buddhist aromatherapy baths and other health practices also suffer from limitations in usage scenarios, inconvenience in carrying, and significant raw material waste, making them ill-suited to the diverse, convenient, and multifunctional personal care needs of modern consumers. In conclusion, there is an urgent need to develop a safe, environmentally friendly, highly efficient, comprehensive, and long-lasting moisturizing, mosquito-repellent, and itch-relieving balm and its preparation method to overcome the numerous bottlenecks of existing technologies. Summary of the Invention

[0005] The present invention aims to provide a moisturizing, mosquito-repellent and anti-itch balm and its preparation method, in order to solve the technical problem that existing balms cannot provide long-lasting moisturizing effects, resulting in a short fragrance retention time.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a moisturizing, mosquito-repellent, and anti-itch balm, comprising the following raw materials in parts by weight: 1-2 parts agarwood, 1-2 parts sandalwood, 1-2 parts chuanxiong rhizome, 1-2 parts pine resin, 1-2 parts cinnamon, 1-2 parts cyperus rhizome, 1-2 parts agastache rugosa, 1-2 parts clove, 1-2 parts cardamom, 1-2 parts nard, 1-2 parts patchouli, 1-2 parts benzoin, 1-2 parts cumin, 1-2 parts white styrax, 1-2 parts acorus calamus, and 1-2 parts artemisia annua.

[0007] Beneficial effects: This balm formula uses a blend of classic aromatic Chinese herbs, combined with beeswax and jojoba seed oil as dual natural bases, to create a complex efficacy system of "aromatic mosquito repellent, heat-clearing and itch-relieving, soothing and repairing, and moisture-locking". The proportions of each component are mild and suitable, and synergistically enhance each other. It combines the advantages of traditional Chinese medicine's aromatic and odor-repelling pharmacology with the skin-care and moisturizing advantages of natural oil bases. It solves the shortcomings of traditional mosquito repellent products, such as high irritation, poor moisturizing properties, weak itch-relieving effect, and short-lasting fragrance. It is highly safe and widely applicable.

[0008] Preferably, as an improvement, the balm further includes a base component, which is beeswax and jojoba seed oil; the amount of beeswax is 20-30% of the total weight of the raw materials, and the amount of jojoba seed oil is 70-170% of the total weight of the raw materials.

[0009] Beneficial Effects: This fragrance formula utilizes a natural dual-base approach, providing the product with excellent moisturizing, water-locking, and shaping stability. Beeswax and jojoba seed oil are selected as the composite base. Beeswax forms a dense, breathable protective film, locking in skin moisture, repairing the skin barrier, and also acting as a fixative and fragrance-locking agent, resulting in a fine, firm texture that is not easily melted. Jojoba seed oil has excellent penetrability, deeply moisturizing the skin, improving dryness and roughness, and softening the skin's stratum corneum. The combination of these two ingredients compensates for the dryness and heaviness of pure wax bases and the tendency of oil bases to flow, while also slowing down the release of herbal aromatic components, achieving long-lasting fragrance and improving the product's application feel and comfort. Furthermore, the high compatibility between the herbal and oil bases ensures system stability and long-lasting fragrance. In particular, the aromatic active ingredients of traditional Chinese medicine can be evenly dispersed in the beeswax and jojoba seed oil system, with excellent compatibility and no problems of layering, precipitation, or deterioration; the oil matrix can effectively encapsulate the volatile oil components of traditional Chinese medicine, slow down the evaporation rate, and greatly extend the duration of mosquito repellency and fragrance, achieving long-lasting mosquito repellency, continuous moisturizing and soothing, and greatly improving the practical value and usage cycle of the product.

[0010] Preferably, as an improvement, the balm maintains a moisturizing rate of ≥89% after 2 hours, ≥79% after 4 hours, and ≥68% after 8 hours at 25°C and 50% relative humidity. This moisturizing performance is superior to that of traditional moisturizing ingredients such as 5% glycerin.

[0011] Beneficial effects: The balm obtained by this solution achieves a high moisturizing rate in 2h, 4h and 8h gradients under standard temperature and humidity conditions. The overall moisturizing effect is slow and the long-lasting water-locking ability is outstanding. The core moisturizing performance is significantly better than the traditional 5% glycerin moisturizing system. It can form a stable and breathable moisturizing barrier on the skin surface, which is suitable for the long-term repair needs of dry, red and itchy skin after mosquito bites. It has the advantages of both immediate moisturizing and long-term stabilization.

[0012] Preferably, as an improvement, this solution also provides a method for preparing a moisturizing, mosquito-repellent, and anti-itch balm, comprising the following steps: Step S1, Raw material pretreatment: Crush the raw materials separately and mix them evenly to obtain mixed raw materials; Step S2, Supercritical Extraction: Mix the raw materials with jojoba seed oil in the matrix components, add the mixture to a supercritical extraction device, use carbon dioxide as the extractant, and collect the extract after supercritical extraction. Step S3, Molecular distillation purification: The extract obtained in step S2 is subjected to molecular distillation to obtain a purified extract; Step S4, Preparation of the paste: Heat the beeswax until it melts, add the purified extract obtained in step S3 and the remaining jojoba seed oil, stir and mix evenly, and then cool and solidify at room temperature to obtain the finished balm.

[0013] Beneficial Effects: This preparation process adopts an integrated process of "raw material pretreatment - supercritical CO2 extraction - molecular distillation purification - low-temperature paste molding," combining green extraction and precise purification technologies to maximize the retention of volatile mosquito-repellent, antipruritic, and moisturizing active ingredients in traditional Chinese medicine, while removing impurities and ineffective components. Combined with low-temperature melting and solidification molding, it balances product purity, activity retention, paste stability, and skin feel, overcoming the drawbacks of traditional decoction and ordinary hot extraction processes, such as high-temperature damage to active ingredients, numerous impurities, low utilization rate of effective components, and poor paste quality. This achieves efficient, green, and standardized preparation of traditional Chinese medicine balms. Through long-term experiments, the applicant discovered that if the raw materials are not pulverized or are unevenly mixed, the dissolution of effective components will be hindered, extraction efficiency will be significantly reduced, the proportion of multiple traditional Chinese medicines in the compound will be unbalanced, and the synergistic effects of mosquito repellency, antipruritic, and moisturizing will be lost. If the raw materials are pulverized too finely, a large amount of ultrafine powder impurities will be generated, increasing the pressure of subsequent purification and easily causing the paste to be rough and prone to pilling when applied. If this process is abandoned and traditional extraction methods are used instead, the high-temperature environment will directly destroy the volatile mosquito-repellent active ingredients in the Chinese medicinal herbs, resulting in a significant reduction in the mosquito-repellent effect and a weakening of the anti-itch and soothing effects. If the herbs are not pre-mixed with jojoba seed oil during extraction, the oil-soluble active ingredients will have poor compatibility with the matrix, making it easy for components to separate and precipitate later, resulting in unstable drug release. Furthermore, if a large amount of coarse fiber, impurities, and ineffective components remain in the extract, it will not only lead to a decrease in the purity of the balm, a cloudy odor, and a rough skin feel, but it will also easily introduce irritating impurities, increasing the risk of skin allergies and redness. At the same time, impurities will occupy matrix space, reducing the load of effective ingredients and significantly weakening the core functions of the balm: moisturizing, mosquito repellent, and anti-itch. If the beeswax melting temperature is too high, it will cause secondary degradation of the heat-sensitive active ingredients of traditional Chinese medicine, resulting in a decrease in product efficacy. If the components are not mixed evenly, it will cause the paste to be of varying hardness and the components to be unbalanced, resulting in localized concentration of medicinal effects and localized loss of efficacy. If it is not allowed to cool and solidify naturally at room temperature, rapid cooling will easily lead to uneven crystallization of the paste and a loose texture. During storage, it is easy to melt, separate oil, and deteriorate, which will greatly shorten the product's shelf life.

[0014] Preferably, as an improvement, in step S1, the particle size of the raw material is 20-40 mesh.

[0015] Beneficial Effects: This solution, employing the aforementioned method, facilitates sufficient contact between carbon dioxide and raw materials while avoiding clogging of the extraction equipment caused by excessively small particle size. This effectively balances the dissolution efficiency of medicinal materials, extraction uniformity, and product purity, meeting the requirements of supercritical fluid extraction. It fully releases the active ingredients of traditional Chinese medicine for mosquito repellency, itch relief, and aromatic moisturizing, ensuring stable efficacy and a uniform, delicate texture for the balm. Through long-term experiments, the applicant discovered that if the medicinal material particles are too large and have a small specific surface area, the cell walls are not sufficiently broken down, making it difficult for the extraction solvent to penetrate the particles. This results in incomplete dissolution of active ingredients, a significantly reduced extraction rate, and a large amount of active ingredients remaining in the residue, leading to raw material waste. Furthermore, uneven extraction of multiple medicinal materials results in weaker and less stable mosquito repellency and itch relief effects in the finished balm. However, if there is too much fine powder in the material and the powder is loose, problems such as fine powder floating, agglomeration, and clogging of equipment channels are likely to occur during supercritical extraction. At the same time, ultrafine powder is very easy to carry coarse fibers, pigments and other ineffective impurities, which increases the difficulty of purification and easily leads to a rough texture and turbid odor in the finished balm. It may even have a grainy feel and pilling, which seriously affects the skin feel and quality stability of the product.

[0016] Preferably, as an improvement, in step S2, the amount of the matrix jojoba seed oil added is 30-50% of the total weight of the mixed raw materials.

[0017] Beneficial effects: This step innovatively incorporates jojoba seed oil as an entrainer into the extraction process. The molecular structure of jojoba seed oil is highly compatible with the non-polar active ingredients in the raw material, which can significantly improve the extraction efficiency, increasing the extraction yield from 4% in the traditional method to 6%. At the same time, it achieves the integration of extraction and initial matrix mixing, simplifying the process flow.

[0018] Preferably, as an improvement, in step S2, the supercritical extraction process is performed for 2-3 hours under the conditions of an extraction temperature of 45-55℃, an extraction pressure of 26-30MPa, and an extraction flow rate of 60-80kg / h.

[0019] Beneficial Effects: This scheme, employing the aforementioned method, facilitates the efficient, stable, and complete extraction of heat-sensitive active ingredients (such as mosquito-repellent, antipruritic, and aromatic moisturizing components) from traditional Chinese medicinal herbs under the premise of low-temperature preservation. It ensures the simultaneous dissolution of effective components from multiple herbs, resulting in high-purity and highly active extracts. This process is compatible with subsequent molecular distillation purification, guaranteeing stable efficacy and uniform quality in the finished balm. Through long-term experiments, the applicant discovered that excessively high system temperatures can damage the molecular structure of volatile essential oils and heat-sensitive active ingredients in traditional Chinese medicinal herbs, causing degradation and inactivation of these active ingredients, directly weakening the core efficacy of the balm in repelling mosquitoes, relieving itching, and soothing. Simultaneously, it easily generates heat-degradation impurities, leading to a cloudy odor and decreased purity in the extracted product. Conversely, excessively low extraction temperatures result in insufficient molecular activity, significantly reduced solvent solubility and penetration, slow and incomplete dissolution of effective components, significantly lower extraction yield, low raw material utilization, and potential uneven extraction of various herbal components, thus disrupting the synergistic effect of the formula. If the extraction pressure is too high, it will significantly increase solvent solubility, dissolving a large amount of ineffective components such as coarse fibers, inert impurities, and fat-soluble pigments while extracting the active ingredients. This increases the pressure required for subsequent molecular distillation purification, resulting in reduced product purity and poorer paste quality. If the extraction pressure is too low, it is impossible to maintain an ideal supercritical extraction state stably. The dissolving capacity of CO2 solvent is significantly weakened, making it difficult to deeply extract the active ingredients from the medicinal materials. This results in low extraction efficiency, a large amount of residual active ingredients, and seriously affects the efficacy and concentration of the finished balm. If the extraction flow rate is too high, the contact time between the solvent and the medicinal materials is insufficient, resulting in excessive scouring. Active ingredients are carried away before they have enough time to fully dissolve, leading to incomplete extraction, low yield, and severe material disturbance, resulting in the inclusion of a large amount of fine powder impurities. If the extraction flow rate is too low, the extraction efficiency is low, the production cycle is significantly prolonged, and local solvent retention and uneven extraction are likely to occur, leading to large differences in the quality of extracted products between batches and poor product stability. If the extraction time is too long, the dissolved active ingredients will undergo oxidation and isomerization, while a large number of ineffective impurities will be continuously extracted, resulting in decreased product purity, reduced efficacy, and increased production energy and time costs. If the extraction time is too short, the extraction reaction will not reach equilibrium, and a large number of active ingredients inside the medicinal materials will not be fully dissolved, resulting in insufficient extraction yield, serious waste of raw materials, low content of effective ingredients in the finished balm, and a significant reduction in its mosquito-repellent, anti-itch, moisturizing, and soothing effects. Preferably, as an improvement, in step S3, the molecular distillation process is carried out at a distillation temperature of 140~160℃, a vacuum degree of 0.1~0.7pa, and a scraping speed of 150~200rad / min.

[0020] Beneficial Effects: Molecular distillation removes impurities and low-boiling-point ineffective components from the extract, improving the purity of active ingredients and further enhancing the efficacy and stability of the balm. This method utilizes the aforementioned approach, enabling precise separation and purification of supercritical fluid extraction products under a mild, low-pressure environment. It efficiently removes coarse fibers, colloids, ineffective impurities, and thermally unstable degradation products, maximizing the retention of the active ingredients in the herbal medicine for mosquito repellency, itch relief, moisturizing, and aromatherapy. This improves the purity and concentration of the extract, ensuring the finished balm is pure, effective, and of uniform quality. Through long-term experiments, the applicant has found that excessively high distillation temperatures can easily cause thermal decomposition and oxidative deactivation of volatile essential oils and aromatic active ingredients in the herbal medicine, leading to a decrease in the core efficacy for mosquito repellency and itch relief. Simultaneously, it easily generates charring impurities and thermal degradation products, resulting in a cloudy odor and reduced purity in the purified product, affecting the texture and efficacy of the balm. Conversely, excessively low distillation temperatures result in insufficient molecular activity, small volatilization differences between effective and impurity components, insufficient separation driving force, incomplete impurity removal, significantly reduced purification effect, and a large amount of residual ineffective impurities in the product, lowering the purity and stability of the finished balm. If the vacuum is too low (e.g., above 0.7 Pa), insufficient negative pressure and a high boiling point will lead to poor distillation and separation efficiency, making it difficult to effectively remove impurities. Furthermore, the high oxygen content in the system can easily cause oxidation and deterioration of active ingredients, resulting in reduced efficacy and product spoilage. If the vacuum is too high (e.g., below 0.1 Pa), some low-boiling-point active aromatic components will be lost along with the lighter components, leading to loss of effective ingredients, reduced yield, weakened aromatherapy and mosquito-repellent effects of the balm, and increased equipment energy consumption and production costs. If the scraper rotation speed is too fast, the liquid film will be too thin, causing material splashing and uneven scraping, resulting in material loss. It will also disrupt the stability of the separation system, preventing some impurities from effectively settling and separating, thus reducing purification precision. If the scraper rotation speed is too slow, the material will be unevenly spread, with a slow turnover rate, leading to localized material retention and overheating accumulation. This not only results in low separation efficiency and incomplete impurity removal but also easily causes localized material coking and deterioration, affecting the overall quality of the product.

[0021] Preferably, as an improvement, in step S4, the beeswax heating temperature is 60~80℃.

[0022] Beneficial Effects: This solution, employing the aforementioned method, facilitates the gentle and complete melting of beeswax, ensuring thorough compatibility and mixing of the beeswax matrix with the purified extracts of traditional Chinese medicine and jojoba seed oil. While fully preserving the active ingredients of the traditional Chinese medicine, it also guarantees the balm's uniform shape, delicate texture, and stable structure, balancing the product's skin feel with its core medicinal effects of repelling mosquitoes, relieving itching, and moisturizing and repairing. Through long-term experiments, the applicant discovered that excessively high heating temperatures can generate high-temperature heat stimulation, easily destroying the volatile essential oils, aromatic active ingredients, and antipruritic active substances in the traditional Chinese medicine extracts. This leads to pyrolysis and oxidative inactivation of the effective ingredients, significantly weakening the balm's core effects of repelling mosquitoes, relieving itching, and providing aromatic soothing. Simultaneously, high temperatures alter the properties of beeswax, making the system prone to localized overheating and aging. After cooling, the balm becomes hard, brittle, prone to cracking and whitening, with a rough skin feel, and accelerates oil oxidation, shortening the product's shelf life. If the heating temperature does not reach the standard for complete melting of beeswax, the beeswax will not melt sufficiently, and solid wax particles will remain in the system. This will lead to uneven mixing with the Chinese herbal extracts and jojoba seed oil, resulting in a disordered material system. The final balm will have problems such as clumping of particles, mottled texture, and uneven hardness. Not only will it have a poor feel when applied to the skin, but it will also cause local enrichment or loss of effective ingredients, resulting in uneven release of the balm's medicinal effects and a significant decrease in stability.

[0023] Preferably, as an improvement, in step S4, the mass ratio of beeswax to jojoba seed oil is 1:2~4.

[0024] Beneficial Effects: This solution employs the aforementioned method, facilitating the creation of a balm that combines excellent molding stability with a moisturizing and skin-friendly feel. It ensures uniform dispersion of the active ingredients in the traditional Chinese medicine, stable system compatibility, and fully leverages its mosquito-repelling, itch-relieving, moisturizing, and soothing effects, resulting in a high-quality traditional Chinese medicine balm with a delicate texture, moderate firmness, and long-lasting fragrance. Through long-term experiments, the applicant discovered that if the oil content is too high and the beeswax content is insufficient, the system lacks sufficient molding support, resulting in a soft, viscous balm that is prone to oiliness, collapse, and deformation, leading to extremely poor molding stability. Furthermore, excessive oil dilutes the concentration of the effective ingredients in the traditional Chinese medicine, reducing the unit efficacy, weakening the mosquito-repelling and itch-relieving effects, and causing the balm to become sticky and heavy, significantly reducing its skin-friendly feel and making it prone to separation and spoilage during storage. If the beeswax content is too high and the oil content is insufficient, the paste will be too rigid and have poor extensibility. After it is formed, the texture will be dry, hard, rough and easy to crack, making it difficult to apply and leaving the skin feeling dry. Insufficient oil will prevent the active ingredients from being fully moisturized and dispersed, which will easily lead to the aggregation and uneven dispersion of the ingredients. This will not only result in a significant reduction in the moisturizing and water-locking ability, but also cause uneven release of the medicine and loss of local efficacy, reducing the overall performance and repair effect of the product.

[0025] The principle and advantages of this scheme are: 1. The raw materials for the perfume balm of this invention are all natural plant ingredients, ensuring high safety. The synergistic effect of each ingredient gives the perfume balm a long-lasting fragrance and comprehensive efficacy. Among them, agarwood, sandalwood, and tonka bean have natural aromatic scents that last a long time; patchouli, clove, and cinnamon have certain mosquito-repellent and antibacterial effects; chuanxiong and nard have a soothing effect on the skin and can relieve itching after mosquito bites; beeswax and jojoba seed oil are both skin-friendly base ingredients. Beeswax has good film-forming and curing properties, while jojoba seed oil has excellent moisturizing properties and good compatibility with the active ingredients in the extract, which can synergistically enhance the moisturizing effect of the perfume balm.

[0026] 2. The preparation method of this invention employs supercritical carbon dioxide extraction technology, which, compared to organic solvent extraction, leaves no solvent residue and is safe and environmentally friendly; compared to steam distillation, the extraction is more thorough, resulting in a higher yield of active ingredients. Simultaneously, the matrix component is incorporated into the extraction process as an entrainer, optimizing the process and improving production efficiency.

[0027] 3. The balm obtained by this method has a moisturizing rate of ≥89% after 2 hours, ≥79% after 4 hours, and ≥68% after 8 hours under an environment of 25℃ and 50% relative humidity. Its moisturizing performance is superior to that of traditional moisturizing ingredient 5% glycerin. Detailed Implementation

[0028] The present invention will be further described in detail below with reference to embodiments, but the implementation of the present invention is not limited thereto. Unless otherwise specified, the technical means used in the following embodiments and experimental examples are conventional means well known to those skilled in the art, and the materials, reagents, etc. used can all be obtained commercially.

[0029] Example 1 This solution provides a method for preparing a moisturizing, mosquito-repellent, and anti-itch balm. In this embodiment, the raw materials of the balm include the following parts by weight: 1 part agarwood, 1 part sandalwood, 1 part chuanxiong rhizome, 1 part pine resin, 1 part cinnamon, 1 part xiangfu (Cyperus rotundus), 1 part ling ling xiang (Acorus calamus), 1 part clove, 1 part cardamom, 1 part nard, 1 part patchouli, 1 part benzoin, 1 part cumin, 1 part white styrax, 1 part shi gua ta (Acorus calamus), and 1 part maizencis. The base components are beeswax and jojoba seed oil, with beeswax accounting for 20% of the total weight of the raw materials and jojoba seed oil accounting for 100% of the total weight of the raw materials.

[0030] The preparation method of perfume includes the following steps: Step S1, Raw material pretreatment: Grind the raw materials separately to 20 mesh and then mix them evenly to obtain mixed raw materials; Step S2, Supercritical Extraction: Take 100g of mixed raw materials, add 30g of jojoba seed oil as an entrainer, mix and add to a supercritical extraction device, use carbon dioxide as the extractant, extract for 2h under the conditions of extraction temperature 45℃, extraction pressure 26MPa and extraction flow rate 60 kg / h, and collect the extract. Step S3, Molecular distillation purification: The extract is subjected to molecular distillation at a distillation temperature of 140℃, a vacuum of 0.1 Pa, and a scraping speed of 150 rad / min. When the distillation rate is less than 0.2 drops / second until it reaches 0, it is considered the distillation endpoint, and the purified extract is obtained. Step S4, Preparation of the paste: Take 20g of beeswax, heat it to 60℃ to melt it, add the above purified extract and the remaining jojoba seed oil (70g), stir evenly, and then cool and solidify at room temperature to obtain the finished balm.

[0031] Example 2 The raw materials for the balm in this embodiment include the following parts by weight: 1.5 parts agarwood, 1.5 parts sandalwood, 1.5 parts chuanxiong, 1.5 parts pine resin, 1.5 parts cinnamon, 1.5 parts xiangfu, 1.5 parts ling wu, 1.5 parts clove, 1.5 parts cardamom, 1.5 parts nard, 1.5 parts patchouli, 1.5 parts benzoin, 1.5 parts cumin, 1.5 parts white styrax, 1.5 parts dandelion, and 1.5 parts shi lian hao. The base components are beeswax and jojoba seed oil, with beeswax accounting for 25% of the total weight of the raw materials and jojoba seed oil accounting for 115% of the total weight of the raw materials.

[0032] The preparation method of perfume includes the following steps: Step S1, Raw material pretreatment: Crush each of the above raw materials to 30 mesh, mix them evenly, and obtain mixed raw materials; Step S2, Supercritical Extraction: Take 100g of mixed raw materials, add 40g of jojoba seed oil, mix and add to a supercritical extraction device, use carbon dioxide as the extractant, control the extraction temperature at 50℃, the extraction pressure at 28MPa, the extraction flow rate at 70kg / h, extract for 2.5h, and collect the extract. Step S3, Molecular distillation purification: The extract is subjected to molecular distillation at a temperature of 150℃, a vacuum of 0.4 Pa, and a scraping speed of 180 rad / min to obtain purified extract; Step S4, Preparation of the paste: Take 25g of beeswax, heat it to 70℃ to melt it, add the above purified extract and the remaining jojoba seed oil (75g), stir evenly, and then cool and solidify at room temperature to obtain the finished balm.

[0033] Example 3 The raw materials for the balm in this embodiment include the following parts by weight: 2 parts agarwood, 2 parts sandalwood, 2 parts chuanxiong, 2 parts pine resin, 2 parts cinnamon, 2 parts xiangfu, 2 parts ling jin, 2 parts clove, 2 parts cardamom, 2 parts gan cao, 2 parts hu guo lan, 2 parts benzoin, 2 parts cumin, 2 parts baijiu, 2 parts shi gua ta, and 2 parts mao lian hao; the base components are beeswax and jojoba seed oil, with beeswax accounting for 30% of the total weight of the raw materials and jojoba seed oil accounting for 140% of the total weight of the raw materials.

[0034] The preparation method of perfume includes the following steps: Step S1, Raw material pretreatment: Crush each of the above raw materials to 40 mesh, mix them evenly, and obtain mixed raw materials; Step S2, Supercritical Extraction: Take 100g of mixed raw materials, add 50g of jojoba seed oil, mix and then add to a supercritical extraction device, use carbon dioxide as the extractant, control the extraction temperature at 55℃, the extraction pressure at 30MPa, the extraction flow rate at 80kg / h, extract for 3h, and collect the extract. Step S3, Molecular distillation purification: The extract is subjected to molecular distillation at a temperature of 160℃, a vacuum of 0.7 Pa, and a scraping speed of 200 rad / min to obtain purified extract; Step S4, Preparation of the paste: Take 30g of beeswax, heat it to 80℃ to melt it, add the above purified extract and the remaining jojoba seed oil (90g), stir evenly, and then cool and solidify at room temperature to obtain the finished balm.

[0035] Comparative Example 1 This comparative example is basically the same as Example 1, except that: the jojoba seed oil in S2 is replaced with an equal amount of sterile water as an entrainer.

[0036] Comparative Example 2 This comparative example is basically the same as Example 1, except that jojoba seed oil is replaced with sweet almond oil.

[0037] In contrast, the jojoba oil used in this formula has a higher saturation than sweet almond oil, making it relatively stable and odorless. Sweet almond oil itself has a nutty aroma and a high content of unsaturated fatty acids, making it prone to rancidity and unpleasant odors, ultimately affecting the fragrance of the balm. Sweet almond oil is a vegetable triglyceride oil, while jojoba oil is a liquid wax ester, the latter having better skin affinity. In particular, when preparing balms, balms with a sweet almond base develop a rancid odor after one year of shelf life, while balms with a jojoba oil base can be stored for more than one year without developing unpleasant odors.

[0038] Comparative Example 3 This comparative example is basically the same as Example 1, except that the extraction temperature in S2 is 40°C.

[0039] Comparative Example 4 This comparative example is basically the same as Example 1, except that the extraction temperature in S2 is 60°C.

[0040] Comparative Example 5 This comparative example is basically the same as Example 1, except that the extraction pressure in S2 is 24 MPa.

[0041] Comparative Example 6 This comparative example is basically the same as Example 1, except that the extraction pressure in S2 is 34 MPa.

[0042] Comparative Example 7 This comparative example is basically the same as Example 1, except that the extraction flow rate in S2 is 50 kg / h.

[0043] Comparative Example 8 This comparative example is basically the same as Example 1, except that the extraction flow rate in S2 is 100 kg / h.

[0044] Comparative Example 9 This comparative example is basically the same as Example 1, except that the extraction time in S2 is 1.5h.

[0045] Comparative Example 10 This comparative example is basically the same as Example 1, except that the extraction time in S2 is 3.5h.

[0046] Comparative Example 11 This comparative example is basically the same as Example 1, except that the distillation temperature in S3 is 130°C.

[0047] Comparative Example 12 This comparative example is basically the same as Example 1, except that the distillation temperature in S3 is 170°C.

[0048] Comparative Example 13 This comparative example is basically the same as Example 1, except that the distillation vacuum degree in S3 is 0.05 Pa.

[0049] Comparative Example 14 This comparative example is basically the same as Example 1, except that the distillation vacuum degree in S3 is 0.8 Pa.

[0050] Comparative Example 15 This comparative example is basically the same as Example 1, except that the distillation scraping speed in S3 is 130 rad / min.

[0051] Comparative Example 16 This comparative example is basically the same as Example 1, except that the distillation scraping speed in S3 is 220 rad / min.

[0052] Experiment Example 1: Component Detection

Characteristics

[0053] [Identification of Active Ingredients] Eugenol, cinnamaldehyde, and eucalyptol were identified by thin-layer chromatography (General Rule 0502) in the 2025 edition of the Chinese Pharmacopoeia.

[0054] [Detection of Active Ingredient Content] The content of eugenol, cinnamaldehyde, and eucalyptol was determined according to the gas chromatography method (General Rule 0521) in the 2025 edition of the Chinese Pharmacopoeia.

[0055] The test results are shown in Table 1.

[0056] Table 1. Performance testing of the perfumes prepared in Examples 1-3 and Comparative Examples 1-16

[0057] Experimental results show that the balm prepared using the proposed method has a higher content of active ingredients. In contrast, in Comparative Examples 1-16, deviations from the optimal range in terms of entrainer type, extraction temperature / pressure / flow rate / time, molecular distillation vacuum, temperature, and scraping speed resulted in insufficient extraction of active ingredients, degradation of heat-sensitive components, and residual impurities. Consequently, the content of active substances was significantly reduced, the spots became blurred and incomplete, and the product quality declined.

[0058] Experiment Example 2: Effect Verification (1) Moisturizing performance test The moisturizing properties of the balms prepared in Examples 1-3 and Comparative Examples 1-2 were tested under the conditions of 25°C and 50% relative humidity, with 5% glycerin as a control sample. The test results are shown in Table 2. Table 2. Moisturizing effects of the balms prepared in Examples 1-3 and Comparative Examples 1-2

[0059] Test results show that the balm prepared by this invention has a higher moisturizing rate than the control sample at different time points, and has excellent moisturizing performance.

[0060] The antipruritic effect was tested using a histamine-induced acute pruritus model in mice to observe the effect of the balm prepared in Example 2 on scratching behavior. Mice were randomly divided into an experimental group and a control group. The experimental group was treated with the balm of the present invention, while the control group was treated with physiological saline. The number of scratches by the mice within 15 minutes was recorded. The results showed that the average number of scratches by the mice in the experimental group was 12.3 times, while that in the control group was 38.7 times, indicating that the balm of the present invention has a significant antipruritic effect.

[0061] (2) Mosquito repellent effect test At 20m 3 Thirty adult mosquitoes were placed in a closed space. The balm prepared in Example 2 was applied to the volunteers' arms (application area 10cm×10cm), and the number of mosquito bites on the volunteers' arms was recorded over 2 hours. The results showed that the average number of bites on the volunteers' arms was 1.2, while the average number of bites in the control group without balm was 8.7, indicating that the balm of the present invention has a certain mosquito-repellent effect.

[0062] (3) Security testing Skin irritation tests were conducted on the balms prepared in Examples 1-3. Twenty volunteers were selected, and the balms were applied to the inside of their arms for seven consecutive days. Skin reactions were observed. The results showed that none of the volunteers experienced skin redness, swelling, itching, or other irritating reactions, indicating that the balms of the present invention have high safety.

[0063] In summary, this solution has the following advantages; 1. This solution is an application and transformation of the Buddhist aromatherapy bath method. The original method involved mixing and crushing the raw materials and adding them to the bathtub for bathing. Now, modern extraction methods are used to collect the fragrance components of the raw materials and prepare them into a more portable and easy-to-use dosage form for a wider range of personal care applications.

[0064] 2. The balm prepared by this method has a long-lasting fragrance, excellent moisturizing effect, and a certain anti-itch effect on the site of mosquito bites. It can also repel mosquitoes to a certain extent.

[0065] 3. The raw material extraction method mentioned in this method is supercritical carbon dioxide extraction. Compared with organic solvent extraction, this extraction method is safer and more environmentally friendly, and leaves no solvent residue. Compared with steam distillation, this extraction method is more thorough and yields more extract.

[0066] 4. During the raw material extraction process, it was discovered that the extract was not a clear, transparent oily liquid, but rather a mixture containing waxy substances with a certain viscosity. This may be related to the solubility of supercritical carbon dioxide, as the non-polar substances in the raw material were fully released. At this point, the extract's state perfectly matches the matrix of perfume-like products, making it a perfect carrier for extract applications.

[0067] 5. Based on the above extraction process, we considered whether the base contents of the balm could be used as an entrainer in the extraction process. This would allow for the extraction of more substances and also enable the initial mixing and formulation of the balm contents during the extraction process. In this way, we increased the extract yield from the original 4% to 6%.

[0068] 6. In the production of the balm, skin-friendly beeswax and jojoba seed oil are used. After the beeswax is heated, a certain proportion of jojoba seed oil and supercritical extract are added, mixed evenly, and then solidified to form the final product.

[0069] 7. We conducted a moisturizing test on the prepared balm using laboratory methods. The test results showed that the moisturizing rates of the test sample at 25℃ and 50% relative humidity were 89.84%, 79.79%, and 68.47% at 2h, 4h, and 8h, respectively. The moisturizing rates of the sample at 2h, 4h, and 8h were higher than those of the control sample with moisturizing effect (5% glycerin), indicating that the balm product has moisturizing effect.

[0070] 8. We conducted an anti-itch test on the prepared balm after mosquito bites. By comparing the results before and after use by users, we concluded that the balm product may have this type of effect. We also observed the scratching behavior of mice by establishing a histamine-induced acute pruritus model.

[0071] The above descriptions are merely embodiments of the present invention, and common knowledge such as specific technical solutions and / or characteristics are not described in detail here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the technical solutions of the present invention, and these should also be considered within the scope of protection of the present invention. These modifications and improvements will not affect the effectiveness of the implementation of the present invention or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A moisturizing, mosquito-repellent, and anti-itch balm, characterized in that: The ingredients include the following parts by weight: 1-2 parts agarwood, 1-2 parts sandalwood, 1-2 parts Sichuan lovage rhizome, 1-2 parts pine resin, 1-2 parts cinnamon, 1-2 parts cyperus rhizome, 1-2 parts agastache rugosa, 1-2 parts cloves, 1-2 parts cardamom, 1-2 parts nard, 1-2 parts patchouli, 1-2 parts benzoin, 1-2 parts cumin, 1-2 parts white styrax, 1-2 parts calamus, and 1-2 parts artemisia annua.

2. The moisturizing, mosquito-repellent, and anti-itch balm according to claim 1, characterized in that: The balm also includes a base component, which is beeswax and jojoba seed oil; the amount of beeswax is 20-30% of the total weight of the raw materials, and the amount of jojoba seed oil is 70-170% of the total weight of the raw materials.

3. The moisturizing, mosquito-repellent, and anti-itch balm according to claim 2, characterized in that: The balm maintains a moisture retention rate of ≥89% for 2 hours, ≥79% for 4 hours, and ≥68% for 8 hours at 25℃ and 50% relative humidity.

4. A method for preparing a moisturizing, mosquito-repellent, and antipruritic balm according to any one of claims 1 to 3, characterized in that: Includes the following steps: Step S1, Raw material pretreatment: Crush the raw materials separately and mix them evenly to obtain mixed raw materials; Step S2, Supercritical Extraction: Mix the raw materials with jojoba seed oil in the matrix components, add the mixture to a supercritical extraction device, use carbon dioxide as the extractant, and collect the extract after supercritical extraction. Step S3, Molecular distillation purification: The extract obtained in step S2 is subjected to molecular distillation to obtain a purified extract; Step S4, Preparation of the paste: Heat the beeswax until it melts, add the purified extract obtained in step S3 and the remaining jojoba seed oil, stir and mix evenly, and then cool and solidify at room temperature to obtain the finished balm.

5. The method for preparing a moisturizing, mosquito-repellent, and anti-itch balm according to claim 4, characterized in that: In step S1, the particle size of the raw material is 20-40 mesh.

6. The method for preparing a moisturizing, mosquito-repellent, and anti-itch balm according to claim 5, characterized in that: In step S2, the amount of jojoba seed oil added is 30-50% of the total weight of the mixed raw materials.

7. A method for preparing a moisturizing, mosquito-repellent, and anti-itch balm according to claim 6, characterized in that: In step S2, the supercritical extraction process is performed for 2-3 hours under the conditions of an extraction temperature of 45-55℃, an extraction pressure of 26-30MPa, and an extraction flow rate of 60-80kg / h.

8. The method for preparing a moisturizing, mosquito-repellent, and anti-itch balm according to claim 7, characterized in that: In step S3, the molecular distillation process is carried out at a distillation temperature of 140~160℃, a vacuum degree of 0.1~0.7pa, and a scraping speed of 150~200rad / min.

9. A method for preparing a moisturizing, mosquito-repellent, and anti-itch balm according to claim 8, characterized in that: In step S4, the beeswax is heated to a temperature of 60-80°C.

10. A method for preparing a moisturizing, mosquito-repellent, and anti-itch balm according to claim 9, characterized in that: In step S4, the mass ratio of beeswax to jojoba seed oil is 1:2~4.

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