A composite water-based personal lubricating composition and a method for preparing the same

Abstract

The present application relates to the technical field of lubricating products, in particular to a composite water-based human body lubricating composition and a preparation method thereof.A composite water-based human body lubricating composition comprises the following components in mass percentage: glycerol 5.0%-20.0%; xanthan gum 0.1%-1.0%; sodium polyacrylate 0.1%-1.5%; hydroxyethyl cellulose 0.1%-1.5%; sodium hyaluronate 0.05%-1.0%; collagen 0.1%-2.0%; octanoyl hydroxamic acid 0.05%-0.2%; p-hydroxyacetophenone 0.1%-0.5%; butanediol 1.0%-5.0%; ethylhexyl glycerin 0.05%-0.3%; citric acid 0.01%-0.5%; and the balance is water.A preparation method of a composite water-based human body lubricating composition is used to prepare the composition as described above.The present application adopts xanthan gum, sodium polyacrylate and hydroxyethyl cellulose to form a composite rheological adjusting system, instead of completely relying on a single thickening material, which is beneficial to taking into account the viscosity, ductility, drawing performance, adhesion and spreading performance of the composition.

Description

Technical Field

[0001] This invention relates to the field of lubricant technology, and in particular to a composite water-based human body lubricant composition and its preparation method. Background Technology

[0002] Personal lubricants are primarily used to reduce friction caused by dryness during contact with human skin and mucous membranes, thereby improving comfort. Existing products can be categorized into different types based on their base system, such as water-based, silicone-based, and oil-based. Water-based lubricants, in particular, are widely used in personal lubrication products due to their ease of cleaning and low residue residue.

[0003] Existing water-based human lubricants are typically based on water and polyols, with the viscosity and lubrication properties of the system adjusted by cellulose, polysaccharides, or synthetic polymers.

[0004] For example, Chinese patent CN118949151A discloses a lubricant containing recombinant collagen, comprising the following ingredients: recombinant collagen, hyaluronic acid, 1,2-propanediol, hydroxyethyl cellulose, ceramide, sodium alginate, β-glucan, carrageenan, linseed oil, gardenia oil, glyceryl monocaprylate, a synergistic composition, and water. While the aforementioned prior art achieves a certain thickening and lubrication effect by adjusting the viscosity of the system using hydroxyethyl cellulose, a single thickener cannot simultaneously maintain both continuous lubricity and spreadability. Under high shear rates, viscosity decreases, leading to a reduction in lubrication effect.

[0005] For example, Chinese patent CN121623021A discloses an antibacterial lubricating gel, its preparation method, and its application. By weight percentage, it comprises: 0.01-0.1% recombinant type III collagen; 0.5-2% hydroxyethyl cellulose; 0.05-3.0% sodium hyaluronate; 0.05-3% xanthan gum; 0.05-10.0% hydrolyzed American ginseng extract; 0.3-1.5% Centella asiatica extract; 0.2-5.0% Sophora flavescens extract; 0.1-2.0% lactic acid; 0.1-1.5% sodium lactate; 1.0-3.0% inulin; 0.5-2.0% α-glucose oligosaccharide; 0.5-4.0% Lactobacillus fermentation product; and the balance being purified water. Although sodium hyaluronate and xanthan gum each possess certain moisturizing and thickening abilities, this method does not solve the stability problem of the polymer system during storage. Furthermore, when used alone at higher concentrations, xanthan gum tends to produce a sticky feeling and affect spreadability.

[0006] Furthermore, existing technologies incorporate collagen-based materials into lubricating compositions. However, these methods typically add collagen as a single moisturizing component without synergistically designing it with a rheology regulation system, making it difficult to simultaneously achieve comprehensive improvements in moisturizing, film formation, and system stability. Additionally, lubricating compositions intended for contact with human skin and mucous membranes require high levels of formulation safety regarding irritation, sensitization, microbial control, and accidental oral contact. Existing methods have shortcomings in designing antimicrobial stabilizing systems; some rely on a single preservative, which may lead to excessive microbial levels or system stratification during long-term storage.

[0007] In summary, existing water-based human body lubricant compositions have significant shortcomings in terms of continuous lubrication performance, spreadability, moisturizing performance, stickiness, cleanliness, formulation stability, and microbial control capabilities. There is an urgent need for a novel water-based human body lubricant composition that can solve the above problems simultaneously. Summary of the Invention

[0008] To overcome the shortcomings of existing technologies, this invention provides a composite water-based human body lubricant composition and its preparation method, which exhibit good continuous lubrication performance, good spreadability, good moisturizing properties, low stickiness, easy cleaning, and high formulation stability. To solve the above technical problems, this invention provides the following technical solution: A composite water-based human body lubricant composition comprising the following components by weight percentage: Glycerin 5.0%~20.0%; Xanthan gum 0.1%~1.0%; Sodium polyacrylate 0.1%~1.5%; Hydroxyethyl cellulose 0.1%~1.5%; Sodium hyaluronate 0.05%~1.0%; Collagen content: 0.1%~2.0%; Capryloyl hydroxamic acid 0.05%~0.2%; p-Hydroxyacetophenone 0.1%~0.5%; Butylene glycol 1.0%~5.0%; Ethylhexylglycerin 0.05%~0.3%; Citric acid 0.01%~0.5%; The remainder is water.

[0009] Xanthan gum, sodium polyacrylate, and hydroxyethyl cellulose together constitute a composite rheology modulator system. Xanthan gum provides hydration, thickening, and water retention; sodium polyacrylate participates in the formation of a hydrophilic gel network; and hydroxyethyl cellulose improves flowability, spreadability, and structural stability. Through this compounding, a balance is achieved between gel stability, extensibility, stringability, lubrication persistence, and cleanliness.

[0010] Glycerin, sodium hyaluronate, and collagen together constitute the moisturizing and lubricating system. Glycerin provides basic moisturizing and lubrication, sodium hyaluronate absorbs and retains water and forms a water-containing lubricating layer, and collagen helps to improve the system's water retention and surface film-forming properties.

[0011] Capryloyl hydroxamic acid, p-hydroxyacetophenone, butylene glycol, and ethylhexylglycerin constitute a complex antimicrobial stabilizing system to improve the microbial stability of the composition during storage and use. Citric acid is used to adjust the pH of the system.

[0012] Based on the above technical solutions, the present invention can also adopt the following further technical solutions: The glycerol has a mass percentage of 8.0% to 15.0%.

[0013] The mass ratio of xanthan gum, sodium polyacrylate and hydroxyethyl cellulose is 1:0.5:0.5 to 1:1.5:1.5.

[0014] The sodium hyaluronate is composed of high molecular weight sodium hyaluronate, medium molecular weight sodium hyaluronate and low molecular weight sodium hyaluronate in a mass ratio of 2:1:1 to 3:2:1.

[0015] The high molecular weight sodium hyaluronate has a molecular weight of 1 million to 2 million Da, the medium molecular weight sodium hyaluronate has a molecular weight of 500,000 to 1 million Da, and the low molecular weight sodium hyaluronate has a molecular weight of 10,000 to 100,000 Da.

[0016] The pH value of the composition is 7.0 to 8.5.

[0017] On the other hand, the present invention also provides the following technical solutions: A method for preparing a composite water-based human body lubricant composition, comprising the following steps: S1. Add the prescribed amount of water to the reaction vessel, add glycerol while stirring continuously and mix well to obtain a mixed solution; S2. Continue stirring the mixed solution obtained in step S1, and add xanthan gum, hydroxyethyl cellulose and sodium polyacrylate in sequence. Keep the temperature at 40~60℃ and stir at 200~500rpm for 15~30 minutes to obtain a uniform gel system. S3. After cooling the gel system obtained in step S2 to 30~40℃, add sodium hyaluronate and collagen, and stir at 200~400 rpm for 10~20 minutes to uniformly disperse and obtain gel system two. S4. After pre-mixing octanoyl hydroxamic acid, p-hydroxyacetophenone, butanediol and ethylhexylglycerin, add them to the gel system two obtained in step S3, and continue stirring until the mixture is uniform to obtain gel system three. S5. Citric acid is added to the gel system obtained in step S4 to adjust the pH to 7.0-8.5, thus obtaining the composition; S6. The composition obtained in step S5 is subjected to degassing treatment, and after passing the inspection, it is quantitatively packaged to obtain the finished composite water-based human body lubricant composition.

[0018] In step S2, the temperature is 45~55℃, the stirring speed is 300~400rpm, and the stirring time is 20~25 minutes.

[0019] In step S3, sodium hyaluronate is prepared by combining high molecular weight, medium molecular weight and low molecular weight, and is added in the order of high molecular weight, medium molecular weight and low molecular weight.

[0020] In step S4, before adding octanoyl hydroxamic acid, p-hydroxyacetophenone, butanediol, and ethylhexylglycerin to gel system II, the mixture is preheated to 30-40°C and mixed for 5-10 minutes.

[0021] Compared with the prior art, the beneficial effects that this invention can achieve are: 1. This invention employs a composite rheology modifier system composed of xanthan gum, sodium polyacrylate, and hydroxyethyl cellulose, rather than relying entirely on a single thickener. This approach helps to balance the viscosity, extensibility, stringiness, adhesion, and spreading properties of the composition. The three rheology modifiers functionally support each other: xanthan gum provides a hydration and thickening base, sodium polyacrylate forms a hydrophilic gel network, and hydroxyethyl cellulose improves flowability—the combined rheological properties of the system are superior to those of any one of them used alone.

[0022] 2. Glycerin, sodium hyaluronate, and collagen form a multi-component moisturizing and lubricating system. Working in conjunction with a complex rheological system, this system allows moisture to remain relatively stable within the lubricating layer, reducing the decline in lubrication performance caused by rapid moisture loss. The combined use of sodium hyaluronates of different molecular weights allows the high-molecular-weight components to form a moisturizing film on the surface, while the low-molecular-weight components penetrate and assist in water retention, producing an effect exceeding that of using a single molecular weight.

[0023] 3. This invention does not rely on silicone oil or oily components to form the main lubricating film. Instead, it forms a lubricating system through water, polyols, and hydrophilic polymers, which has the characteristics of being easy to clean and having a low residue feel, characteristic of water-based products.

[0024] 4. The synergistic design of the complex antibacterial and stabilizing system (capryloyl hydroxamic acid, p-hydroxyacetophenone, butylene glycol and ethylhexylglycerin) improves the microbial control capability of the composition during storage and use, while reducing the risk of skin sensitization through overall formulation design. Detailed Implementation

[0025] The present invention provides a further description of a composite water-based human body lubricant composition and its preparation method.

[0026] Example 1: A composite water-based human body lubricant composition comprising the following components by weight percentage: glycerin 5.0%; xanthan gum 0.1%; sodium polyacrylate 0.1%; hydroxyethyl cellulose 0.1%; sodium hyaluronate 0.05%; collagen 0.1%; capryloyl hydroxamic acid 0.05%; p-hydroxyacetophenone 0.1%; butylene glycol 1.0%; ethylhexylglycerin 0.05%; citric acid 0.01%; the balance being water.

[0027] Its preparation method includes the following steps: S1. Add the prescribed amount of water to the reaction vessel, add glycerol while stirring continuously and mix well to obtain a mixed solution; S2. Continue stirring the mixed solution obtained in step S1, and add xanthan gum, hydroxyethyl cellulose and sodium polyacrylate in sequence. Keep the temperature at 50°C and stir at 400 rpm for 20 minutes to obtain a uniform gel system. S3. After cooling the gel system obtained in step S2 to 35°C, add sodium hyaluronate and collagen, and stir at 300 rpm for 15 minutes to uniformly disperse and obtain gel system two. S4. After pre-mixing octanoyl hydroxamic acid, p-hydroxyacetophenone, butanediol and ethylhexylglycerin, add them to the gel system two obtained in step S3, and continue stirring until the mixture is uniform to obtain gel system three. S5. Citric acid is added to the gel system obtained in step S4 to adjust the pH to 7.0, thus obtaining the composition; S6. The composition obtained in step S5 is subjected to degassing treatment, and after passing the inspection, it is quantitatively packaged to obtain the finished composite water-based human body lubricant composition.

[0028] Example 2: A composite water-based human body lubricant composition comprising the following components by weight percentage: glycerin 20.0%; xanthan gum 1.0%; sodium polyacrylate 1.5%; hydroxyethyl cellulose 1.5%; sodium hyaluronate 1.0%; collagen 2.0%; capryloyl hydroxamic acid 0.2%; p-hydroxyacetophenone 0.5%; butylene glycol 5.0%; ethylhexylglycerin 0.3%; citric acid 0.5%; the balance being water.

[0029] Its preparation method includes the following steps: S1. Add the prescribed amount of water to the reaction vessel, add glycerol while stirring continuously and mix well to obtain a mixed solution; S2. Continue stirring the mixed solution obtained in step S1, and add xanthan gum, hydroxyethyl cellulose and sodium polyacrylate in sequence. Keep the temperature at 50°C and stir at 300 rpm for 25 minutes to obtain a uniform gel system. S3. After cooling the gel system obtained in step S2 to 35°C, add sodium hyaluronate and collagen, and stir at 300 rpm for 15 minutes to uniformly disperse and obtain gel system two. S4. After pre-mixing octanoyl hydroxamic acid, p-hydroxyacetophenone, butanediol and ethylhexylglycerin, add them to the gel system two obtained in step S3, and continue stirring until the mixture is uniform to obtain gel system three. S5. Citric acid is added to the gel system obtained in step S4 to adjust the pH to 8.0, thus obtaining the composition; S6. The composition obtained in step S5 is subjected to degassing treatment, and after passing the inspection, it is quantitatively packaged to obtain the finished composite water-based human body lubricant composition.

[0030] Example 3: A composite water-based human body lubricant composition comprising the following components by weight percentage: glycerin 15.0%; xanthan gum 0.5%; sodium polyacrylate 1.2%; hydroxyethyl cellulose 1.0%; sodium hyaluronate 0.5%; collagen 1.5%; capryloyl hydroxamic acid 0.15%; p-hydroxyacetophenone 0.3%; butanediol 3.0%; ethylhexylglycerin 0.15%; citric acid 0.3%; the balance being water.

[0031] Its preparation method includes the following steps: S1. Add the prescribed amount of water to the reaction vessel, add glycerol while stirring continuously and mix well to obtain a mixed solution; S2. Continue stirring the mixed solution obtained in step S1, and add xanthan gum, hydroxyethyl cellulose and sodium polyacrylate in sequence. Keep the temperature at 50°C and stir at 400 rpm for 20 minutes to obtain a uniform gel system. S3. After cooling the gel system obtained in step S2 to 35°C, add sodium hyaluronate and collagen, and stir at 300 rpm for 15 minutes to uniformly disperse and obtain gel system two. S4. After pre-mixing octanoyl hydroxamic acid, p-hydroxyacetophenone, butanediol and ethylhexylglycerin, add them to the gel system two obtained in step S3, and continue stirring until the mixture is uniform to obtain gel system three. S5. Citric acid is added to the gel system obtained in step S4 to adjust the pH to 7.5, thus obtaining the composition; S6. The composition obtained in step S5 is subjected to degassing treatment, and after passing the inspection, it is quantitatively packaged to obtain the finished composite water-based human body lubricant composition.

[0032] Third-party type testing of a 2.5 mL sample corresponding to the formulation of this invention showed that 16 indicators, including appearance, color, odor, cold resistance, heat resistance, pH, heavy metals, and microorganisms, met the corresponding requirements of Q / JYYY 009-2022; the measured pH value of the sample was 8.0; lead, total arsenic, mercury, and cadmium were not detected; Pseudomonas aeruginosa, Staphylococcus aureus, coliform bacteria, and hemolytic streptococci were not detected; and the total number of fungi and bacteria met the limit requirements.

[0033] In accordance with the Cosmetic Safety Technical Specifications, a skin allergy test was conducted on guinea pigs. No skin allergy was observed under the test conditions, indicating that the test sample has a low risk of skin sensitization.

[0034] Acute oral toxicity testing was conducted in accordance with the Cosmetic Safety Technical Specifications. The oral LD50 of the test sample in KM mice was greater than 5000 mg / kg BW, and it was rated as "practically non-toxic". This result is used to describe the acute oral toxicity level and is not presented as a food or edible property.

[0035] The present invention has been described with reference to preferred embodiments; however, those skilled in the art will understand that various changes in form and detail may be made within the scope of the claims.

Claims

1. A composite water-based human body lubricant composition, characterized in that... Components include the following percentage by weight: Glycerin 5.0%~20.0%; Xanthan gum 0.1%~1.0%; Sodium polyacrylate 0.1%~1.5%; Hydroxyethyl cellulose 0.1%~1.5%; Sodium hyaluronate 0.05%~1.0%; Collagen content: 0.1%~2.0%; Capryloyl hydroxamic acid 0.05%~0.2%; p-Hydroxyacetophenone 0.1%~0.5%; Butylene glycol 1.0%~5.0%; Ethylhexylglycerin 0.05%~0.3%; Citric acid 0.01%~0.5%; The remainder is water.

2. The composite water-based human body lubricant composition according to claim 1, characterized in that... The glycerol has a mass percentage of 8.0% to 15.0%.

3. The composite water-based human body lubricant composition according to claim 1, characterized in that... The mass ratio of xanthan gum, sodium polyacrylate and hydroxyethyl cellulose is 1:0.5:0.5 to 1:1.5:1.

5.

4. The composite water-based human body lubricant composition according to claim 1, characterized in that... The sodium hyaluronate is composed of high molecular weight sodium hyaluronate, medium molecular weight sodium hyaluronate and low molecular weight sodium hyaluronate in a mass ratio of 2:1:1 to 3:2:

1.

5. A composite water-based human body lubricant composition according to claim 4, characterized in that... The high molecular weight sodium hyaluronate has a molecular weight of 1 million to 2 million Da, the medium molecular weight sodium hyaluronate has a molecular weight of 500,000 to 1 million Da, and the low molecular weight sodium hyaluronate has a molecular weight of 10,000 to 100,000 Da.

6. The composite water-based human body lubricant composition according to claim 1, characterized in that... The pH value of the composition is 7.0 to 8.

5.

7. A method for preparing a composite water-based human body lubricant composition, characterized in that... The preparation of the composition according to claims 1-6 comprises the following steps: S1. Add the prescribed amount of water to the reaction vessel, add glycerol while stirring continuously and mix well to obtain a mixed solution; S2. Continue stirring the mixed solution obtained in step S1, and add xanthan gum, hydroxyethyl cellulose and sodium polyacrylate in sequence. Keep the temperature at 40~60℃ and stir at 200~500rpm for 15~30 minutes to obtain a uniform gel system. S3. After cooling the gel system obtained in step S2 to 30~40℃, add sodium hyaluronate and collagen, and stir at 200~400 rpm for 10~20 minutes to uniformly disperse and obtain gel system two. S4. After pre-mixing octanoyl hydroxamic acid, p-hydroxyacetophenone, butanediol and ethylhexylglycerin, add them to the gel system two obtained in step S3, and continue stirring until the mixture is uniform to obtain gel system three. S5. Citric acid is added to the gel system obtained in step S4 to adjust the pH to 7.0-8.5, thus obtaining the composition; S6. The composition obtained in step S5 is subjected to degassing treatment, and after passing the inspection, it is quantitatively packaged to obtain the finished composite water-based human body lubricant composition.

8. The method for preparing a composite water-based human body lubricant composition according to claim 7, characterized in that... In step S2, the temperature is 45~55℃, the stirring speed is 300~400rpm, and the stirring time is 20~25 minutes.

9. The method for preparing a composite water-based human body lubricant composition according to claim 7, characterized in that... In step S3, sodium hyaluronate is prepared by combining high molecular weight, medium molecular weight and low molecular weight, and is added in the order of high molecular weight, medium molecular weight and low molecular weight.

10. The method for preparing a composite water-based human body lubricant composition according to claim 7, characterized in that... In step S4, before adding octanoyl hydroxamic acid, p-hydroxyacetophenone, butanediol, and ethylhexylglycerin to gel system II, the mixture is preheated to 30-40°C and mixed for 5-10 minutes.