Intelligent biological sample storage system

Abstract

The application discloses a kind of biological sample intelligent storage systems, including operation cabin, transfer cabin, storage cabin and refrigeration mechanism;The side of storage cabin is provided with operation cabin and transfer cabin, and the transfer of sample is transferred and docked between transfer cabin and operation cabin and storage cabin, and the refrigeration mechanism is arranged on the storage cabin, and the refrigeration mechanism can carry out refrigeration temperature control inside the storage cabin.The beneficial effects of the present application are that the inside of the storage cabin is refrigerated by the refrigeration mechanism, and the refrigeration mechanism can use multiple temperature control methods, suitable for different working condition requirements, can be switched flexibly and quickly, and can achieve full-automatic access and transfer work of picking tube;The equipment uses general structure design, can be compatible with multiple specifications storage panel, and adapts to different types of biological sample storage requirements.

Description

Technical Field

[0001] This invention relates to the field of sample storage technology, and in particular to an intelligent biological sample storage system. Background Technology

[0002] Addressing the industry pain points of traditional biological sample storage equipment, such as limited temperature range adjustment, single temperature control method, slow response to operating condition switching, poor rack adaptability, weak sample storage and retrieval versatility, and difficulty in achieving both wide-range precise temperature control and efficient airtight storage and retrieval.

[0003] To address this, the inventors designed an intelligent storage system for biological samples. Summary of the Invention

[0004] The purpose of this section is to outline some aspects of embodiments of the present invention and to briefly describe some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be construed as limiting the scope of the invention.

[0005] In view of the problems existing in the above or prior art, the present invention is proposed.

[0006] Therefore, the purpose of this invention is to provide a smart storage system for biological samples, which can cool the inside of the storage chamber through a cooling mechanism. The cooling mechanism can adopt multiple temperature control methods and can be switched flexibly and quickly, taking into account both wide-temperature range precise temperature control and efficient airtight storage and retrieval, and can realize fully automated storage, retrieval, tube picking and transfer.

[0007] To solve the above-mentioned technical problems, the present invention provides the following technical solution: a biological sample intelligent storage system, which includes an operation chamber, a transfer chamber, a storage chamber and a refrigeration mechanism; the operation chamber and the transfer chamber are arranged on the side of the storage chamber, and the transfer chamber is connected to the operation chamber and the storage chamber for sample transfer; the refrigeration mechanism is arranged on the storage chamber and can refrigerate and control the temperature inside the storage chamber.

[0008] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the refrigeration mechanism includes a Stirling refrigeration component, which is disposed on the side wall of the storage chamber. The Stirling refrigeration component can control the temperature inside the storage chamber by starting and stopping.

[0009] In a preferred embodiment of the intelligent biological sample storage system of the present invention, the Stirling cooling component includes a driving module and a heat-absorbing module; the driving module is connected to the heat-absorbing module, and the heat-absorbing module is wound around the outer wall of the storage chamber, and the heat-absorbing module can absorb heat and control the temperature of the storage chamber.

[0010] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the heat absorption module includes a first heat absorption tube and a second heat absorption tube; the first heat absorption tube and the second heat absorption tube can be bent and wound multiple times to fit against the outer wall of the storage chamber, and the first heat absorption tube and the second heat absorption tube are connected at the bottom end of the outer wall of the storage chamber.

[0011] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the refrigeration mechanism further includes a liquid nitrogen refrigeration component; the liquid nitrogen refrigeration component is installed inside the storage chamber and can control the temperature of the sample inside the storage chamber.

[0012] In a preferred embodiment of the intelligent biological sample storage system of the present invention, the liquid nitrogen cooling component includes a liquid nitrogen cylinder and a liquid supply pipeline control module; the liquid supply pipeline control module is located at the upper end of the storage chamber, and the liquid supply pipeline control module can add liquid to the liquid nitrogen cylinder through the pipeline.

[0013] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the refrigeration mechanism includes a circulating refrigeration component; the circulating refrigeration component is disposed inside the storage chamber, and liquid nitrogen is disposed inside the circulating refrigeration component, and the liquid nitrogen in the circulating refrigeration component can continuously control the temperature of the sample in the storage chamber with zero consumption.

[0014] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the circulating cooling component includes a sealed cavity, a liquefaction element is provided at the upper end of the sealed cavity, and a heat preservation element is provided on the side of the liquefaction element; the liquefaction element can liquefy vaporized liquid nitrogen, and the heat preservation element can keep the liquefaction element warm.

[0015] In a preferred embodiment of the intelligent biological sample storage system of the present invention, the liquefaction component includes liquefaction fins and a refrigeration drive module; the liquefaction fins are disposed at the upper end of the sealed cavity, the refrigeration drive module can refrigerate the liquefaction fins, and the liquefaction fins can circulate and liquefy vaporized liquid nitrogen.

[0016] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the storage compartment includes a vertical storage refrigerator, and a rotating storage component is provided inside the vertical storage refrigerator; the rotating storage component can rotatably store the plate rack and the sample.

[0017] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the storage compartment is provided with an access channel; the transfer compartment can access the samples inside the operation compartment through the access channel.

[0018] In a preferred embodiment of the intelligent biological sample storage system of the present invention, the transfer chamber includes an extraction component and a rotary sealing door component; the rotary sealing door component is disposed on the extraction component, the rotary sealing door component can drive the extraction component to rotate, and the rotary sealing door component can open or seal the access channel.

[0019] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the extraction component includes an extraction chamber, in which a shovel module is provided. The shovel module can be raised and lowered and can be extended and retracted horizontally within the extraction chamber. The transfer chamber is also provided with a shovel transfer channel, and the shovel module can be docked with the storage chamber or the operation chamber through the storage channel or the shovel transfer channel, respectively.

[0020] As a preferred embodiment of the intelligent biological sample storage system of the present invention, it further includes a docking component, which is retractable and movable to receive the transfer tank and drives the transfer tank to rise and fall to dock with the operating cabin.

[0021] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the operating chamber is equipped with a grasping component that can grasp and pick up the plates and sample tubes transported by the transfer chamber and docking component; the grasping component can grasp, open and transfer the lid of the transfer tank.

[0022] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the rotating storage component includes a rotating frame drive module and a rotating frame. The rotating frame drive module can drive the rotating frame to rotate, and the rotating frame can store the plate frame. The rotating frame includes a first basket frame and a second basket frame. The first basket frames are arranged in a circumferential array, and a second basket frame is arranged between each pair of first basket frames. The first basket frames and the second basket frames can support and store plates of different specifications.

[0023] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the grasping component includes a three-dimensional moving support frame, on which a grasping lifting module and a cap-moving module are slidably arranged. A clamping module and an aspiration module are arranged on both sides of the grasping lifting module. The grasping lifting module can drive the clamping module and the aspiration module to move up and down. The clamping module can grasp and transfer the caps of the plate frame and the transfer tank. The aspiration module can aspirate and transfer the sample tubes. The cap-moving module can open or seal the docking channel in the operating chamber.

[0024] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the gripping module includes a rotating frame module, a gripper module, and a clamping plate; the rotating frame module is provided with a gripper module, the gripper module is provided with a clamping plate, the rotating frame module can drive the gripper module to rotate, the clamping plate can clamp the frame, and the gripper module can grasp and transfer the frame and the lid of the transfer tank.

[0025] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the cover-moving module includes a lifting support frame and a sealing cover; the sealing cover is set on the lifting support frame, the lifting support frame can drive the sealing cover to move up and down, and can rotate to open or seal the docking channel.

[0026] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the transfer chamber further includes a push-pull sealing door assembly, which can open or seal the access channel. The push-pull sealing door assembly includes a screw drive module, a driven member, a second sealing door, a support limiting member, and a sliding shaft. The driven member is connected to the screw drive module and the second sealing door on both sides. The support limiting member is provided with a rotatable sliding shaft, and the second sealing door is slidably connected to the sliding shaft. The screw drive module can drive the driven member to move and guide the second sealing door to slide along the sliding shaft. The second sealing door can drive the sliding shaft to rotatably seal the docking channel opening.

[0027] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the clamping module further includes a rotating frame module, a flexible clamping component, and a second driving component; the flexible clamping component is provided below the rotating frame module, and the second driving component is provided on the flexible clamping component, which can drive the flexible clamping component to grip the plate frame or sample tube.

[0028] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the clamping module further includes a spring-loaded component, which is disposed on the flexible clamping component and drives the flexible clamping component to expand and spring back.

[0029] As a preferred embodiment of the intelligent biological sample storage system of the present invention, the storage chamber includes a liquid nitrogen tank, and a rotating storage component is provided inside the liquid nitrogen tank; the rotating storage component can rotatably store the plate and the sample; the liquid nitrogen tank is filled with liquid nitrogen, which can be used to cool the sample on the rotating storage component.

[0030] The beneficial effects of this invention are as follows: This invention uses a refrigeration mechanism to cool the interior of the storage chamber, and the refrigeration mechanism can adopt multiple temperature control methods to meet different working conditions and can be switched flexibly and quickly. It takes into account both wide-temperature range precise temperature control and efficient sealed storage and retrieval, and can realize fully automated storage, retrieval, tube picking and transfer. The equipment adopts a universal structural design, which is compatible with various specifications of storage racks and can adapt to different types of biological sample storage needs. Attached Figure Description

[0031] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the following description of the embodiments will be briefly introduced. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Wherein: Figure 1 This is a three-dimensional schematic diagram of a biological sample intelligent storage system.

[0032] Figure 2 A front view of a biological sample intelligent storage system.

[0033] Figure 3 for Figure 2 A schematic diagram of section AA of the intelligent storage system for biological samples.

[0034] Figure 4 A three-dimensional schematic diagram of the Stirling cooling component for an intelligent biological sample storage system.

[0035] Figure 5 A three-dimensional schematic diagram of the rotating storage component of a biological sample intelligent storage system.

[0036] Figure 6 A three-dimensional schematic diagram of the extraction component of a biological sample intelligent storage system.

[0037] Figure 7 This is a schematic diagram of the interior of the storage compartment of a biological sample intelligent storage system.

[0038] Figure 8 This is a schematic diagram of the interior of the operating cabin of an intelligent biological sample storage system.

[0039] Figure 9 A three-dimensional schematic diagram of the grasping component of a biological sample intelligent storage system.

[0040] Figure 10 A three-dimensional schematic diagram of the circulating cooling component of an intelligent biological sample storage system.

[0041] Figure 11 A three-dimensional schematic diagram of the sealed cavity of a biological sample intelligent storage system.

[0042] Figure 12 for Figure 11 A top view of the intelligent storage system for biological samples.

[0043] Figure 13 for Figure 12 Cross-sectional view of section BB of the intelligent storage system for biological samples.

[0044] Figure 14 A three-dimensional schematic diagram of the grasping component from another perspective of the intelligent storage system for biological samples.

[0045] Figure 15 A three-dimensional schematic diagram of the push-pull sealing door assembly of a biological sample intelligent storage system.

[0046] Figure 16 Schematic diagram of another embodiment of the gripper module of the intelligent biological sample storage system Figure 17 for Figure 16 A top view of the intelligent storage system for biological samples.

[0047] Figure 18 for Figure 17 A schematic diagram of the CC section of the intelligent storage system for biological samples.

[0048] Figure 19 This is a schematic diagram of another implementation of the gripper module of a biological sample intelligent storage system.

[0049] Figure 20 A three-dimensional schematic diagram of the liquid nitrogen tank in an intelligent biological sample storage system.

[0050] Figure 21 for Figure 20 A top-down view of the intelligent storage system for biological samples.

[0051] Figure 22 for Figure 21 A cross-sectional view of the DD section of the intelligent biological sample storage system.

[0052] Figure 23 A three-dimensional schematic diagram of the Stirling cooling component inside the storage tank of a biological sample intelligent storage system.

[0053] Reference numerals: 1. Operation compartment; 2. Transfer compartment; 3. Storage compartment; 4. Refrigeration mechanism; 4. Stirling refrigeration assembly; 41. Drive module; 411. Heat absorption module; 412. First heat absorption pipe; 4121. Second heat absorption pipe; 4122. Liquid nitrogen refrigeration assembly; 42. Liquid nitrogen cylinder; 421. Liquid supply pipeline control module; 422. Circulating refrigeration assembly; 43. Sealing cavity; 431. Liquefaction component; 432. Insulation component; 433. Liquefaction fins; 4321. Refrigeration drive module; 4322. Vertical storage refrigerator; 31. Rotary storage assembly; 32. Extraction assembly; 21. Rotary sealing door assembly; 22. Extraction compartment; 211. Shovel module; 212. Docking assembly; 5. Transfer tank; 6. Grabbing assembly; 7. Rotating frame drive module; 321. Rotating frame; 322. First basket frame; 3221. Second basket frame, 3223; Three-dimensional moving support frame, 71; Grabbing and lifting module, 75; Cover moving module, 74; Clamping module, 72; Suction module, 73; Rotating frame module, 721; Gripper module, 722; Pressing plate, 723; Lifting support frame, 741; Sealing cover, 742; Push-pull sealing door assembly, 23; Screw drive module, 231; Follower, 232; Second sealing door, 233; Support limiting component, 234; Sliding shaft, 235; Flexible gripper, 725; Second drive component, 726; Rebound component, 727; Sliding magnet, 7261; Fixed magnet, 7262; First gripper, 7251; Second gripper, 7252; Support plate, 7253; Third gripper, 7254; Fourth gripper, 7255; Expansion module, 7263; Stop module, 7264; Detailed Implementation

[0054] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0055] Many specific details are set forth in the following description in order to provide a full understanding of the invention. However, the invention may also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the invention. Therefore, the invention is not limited to the specific embodiments disclosed below.

[0056] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that is mutually exclusive with other embodiments. Example 1

[0057] Reference Figures 1-3 This is the first embodiment of the present invention, which provides a biological sample intelligent storage system, including an operation chamber 1, a transfer chamber 2, a storage chamber 3, and a cooling mechanism 4; the operation chamber 1 and the transfer chamber 2 are provided on the side of the storage chamber 3, the transfer chamber 2 can dock with the operation chamber 1 and the storage chamber 3 for sample transfer, etc., the cooling mechanism 4 can cool the storage chamber 3, and can control and adjust the internal temperature of the storage chamber 3, and the storage chamber 3 can store sample tubes and racks at low temperatures.

[0058] Specifically, it includes an operation chamber 1, a transfer chamber 2, a storage chamber 3, and a refrigeration mechanism 4; the operation chamber 1 and the transfer chamber 2 are located on the side of the storage chamber 3, and the transfer chamber 2 is used for sample transfer docking with the operation chamber 1 and the storage chamber 3. The refrigeration mechanism 4 is located on the storage chamber 3 and can refrigerate and control the temperature inside the storage chamber 3.

[0059] In summary, the present invention allows the transfer chamber 2 to dock with the operation chamber 1 and the storage chamber 3 respectively. The transfer chamber 2 can be used to transfer sample racks between the operation chamber 1 and the storage chamber 3. The storage chamber 3 can be used to store and support batches of racks of different specifications. The operation chamber 1 can be used to pick and transfer sample tubes on the racks. The refrigeration mechanism 4 can control the temperature inside the storage chamber 3, enabling low-temperature storage of samples. Example 2

[0060] Reference Figures 1-9 and Figure 14This is the second embodiment of the present invention. In the previous embodiment, the intelligent biological sample storage system includes an operation chamber 1, a transfer chamber 2, a storage chamber 3, and a cooling mechanism 4. The operation chamber 1 and the transfer chamber 2 are provided on the side of the storage chamber 3. The transfer chamber 2 can dock with the operation chamber 1 and the storage chamber 3 for sample transfer, etc. The cooling mechanism 4 can cool the storage chamber 3 and control and adjust the temperature inside the storage chamber 3. The storage chamber 3 can store sample tubes and racks at low temperatures.

[0061] Specifically, it includes an operation chamber 1, a transfer chamber 2, a storage chamber 3, and a refrigeration mechanism 4; the operation chamber 1 and the transfer chamber 2 are located on the side of the storage chamber 3, and the transfer chamber 2 is used for sample transfer docking with the operation chamber 1 and the storage chamber 3. The refrigeration mechanism 4 is located on the storage chamber 3 and can refrigerate and control the temperature inside the storage chamber 3.

[0062] Furthermore, the refrigeration mechanism 4 includes a Stirling refrigeration component 41, which is installed on the side wall of the storage compartment 3. The Stirling refrigeration component 41 can control the temperature inside the storage compartment 3 by starting and stopping it.

[0063] It should be noted that the Stirling refrigeration unit 41 relies on the Stirling engine to achieve precise control over an ultra-wide temperature range of -20℃ to -110℃. It completes the automatic switching of operating conditions by starting and stopping the Stirling engine, and the temperature control switching logic is simple and the response is efficient.

[0064] Furthermore, the Stirling refrigeration assembly 41 includes a drive module 411 and a heat absorption module 412; the drive module 411 is connected to the heat absorption module 412, and the heat absorption module 412 is wound around the outer wall of the storage compartment 3, and the heat absorption module 412 can absorb heat and control the temperature of the storage compartment 3.

[0065] It should be noted that by wrapping the heat-absorbing module 412 around the outer wall of the storage compartment 3, the storage compartment 3 can be cooled and its heat absorbed, thereby reducing the temperature of the storage compartment 3.

[0066] Furthermore, the heat absorption module 412 includes a first heat absorption pipe 4121 and a second heat absorption pipe 4122; the first heat absorption pipe 4121 and the second heat absorption pipe 4122 can be bent and wrapped multiple times to fit against the outer wall of the storage compartment 3, and the first heat absorption pipe 4121 and the second heat absorption pipe 4122 are connected at the bottom end of the outer wall of the storage compartment 3.

[0067] It should be noted that the first heat absorption pipe 4121 is output from the port of the drive module 411 and is attached to the outer wall of the storage compartment 3 in a curved shape. At the bottom of the outer wall, the first heat absorption pipe 4121 is connected to the second heat absorption pipe 4122, and the second heat absorption pipe 4122 is attached to the outer wall of the storage compartment 3 in a curved shape from bottom to top. The second heat absorption pipe 4122 is also connected to the drive module 411.

[0068] It should be noted that the cooling of a Stirling engine is essentially a reverse Stirling cycle: through external mechanical work, the working fluid helium / hydrogen undergoes four processes in a sealed cylinder: isothermal compression and heat release, isochoric reheat, isothermal expansion and heat absorption, and isochoric cooling, thus "transferring" heat from the low-temperature end to the high-temperature end and dissipating it, thereby achieving cooling.

[0069] Furthermore, the refrigeration mechanism 4 also includes a liquid nitrogen refrigeration component 42; the liquid nitrogen refrigeration component 42 is installed inside the storage chamber 3, and the liquid nitrogen refrigeration component 42 can control the temperature of the sample inside the storage chamber 3.

[0070] It should be noted that the storage chamber 3 is also equipped with a liquid nitrogen cooling assembly 42, which contains liquid nitrogen, and the liquid nitrogen can be used to cool the interior of the storage chamber 3.

[0071] It should be noted that in this embodiment, the storage compartment 3 can use liquid nitrogen cooling component 42 alone, or Stirling cooling component 41 alone; it can also use both liquid nitrogen cooling component 42 and Stirling cooling component 41, with both working together for cooling; when both liquid nitrogen cooling component 42 and Stirling cooling component 41 are available, the liquid nitrogen cooling component 42 or Stirling cooling component 41 can be switched at any time for cooling operation according to the applicable scenario.

[0072] Furthermore, the liquid nitrogen refrigeration assembly 42 includes a liquid nitrogen cylinder 421 and a liquid supply pipeline control module 422; the liquid supply pipeline control module 422 is located at the upper end of the storage compartment 3, and the liquid supply pipeline control module 422 can add liquid to the liquid nitrogen cylinder 421 through the pipeline.

[0073] It should be noted that liquid nitrogen is installed inside the liquid nitrogen cylinder 421 to preserve the sample inside at low temperature. When the liquid nitrogen in the liquid nitrogen cylinder 421 evaporates, the liquid supply pipeline control module 422 can add liquid to the liquid nitrogen cylinder 421 to replenish the liquid nitrogen and allow the liquid nitrogen to continuously cool the sample tube at low temperature.

[0074] Furthermore, the storage compartment 3 includes a vertical storage refrigerator 31, and a rotating storage component 32 is provided inside the vertical storage refrigerator 31; the rotating storage component 32 can rotate and store the rack and samples.

[0075] It should be noted that the first heat-absorbing pipe 4121 and the second heat-absorbing pipe 4122 are attached and wrapped around the vertical storage refrigerator 31. A thickened heat-insulating body is also provided on the outer side of the first heat-absorbing pipe 4121 and the second heat-absorbing pipe 4122, which can be used to further insulate the heat.

[0076] Furthermore, the storage compartment 3 is equipped with an access channel; the transfer compartment 2 can access samples inside the operation compartment 1 through the access channel.

[0077] Furthermore, the transfer chamber 2 includes an extraction component 21 and a rotary sealing door component 22; the rotary sealing door component 22 is disposed on the extraction component 21, the rotary sealing door component 22 can drive the extraction component 21 to rotate, and the rotary sealing door component 22 can open or seal the access channel.

[0078] It should be noted that the extraction component 21 and the rotary sealing door component 22 can rotate simultaneously. The rotary sealing door component 22 can open or seal the access channel, and the extraction component 21 can dock with the operating compartment 1 or the storage compartment 3.

[0079] Furthermore, the extraction component 21 includes an extraction chamber 211, in which a scooping module 212 is installed. The scooping module 212 can be raised and lowered within the extraction chamber 211 and can be extended and retracted horizontally. The transfer chamber 2 is also provided with a scooping transfer channel opening, through which the scooping module 212 can dock with the storage chamber 3 or the operation chamber 1 respectively via the storage channel or the scooping transfer channel opening.

[0080] It should be noted that, under normal conditions, the shovel transfer channel opening can be sealed using a lifting sealing door. When docking is required, the lifting sealing door is opened to reduce temperature exchange.

[0081] It should be noted that the extraction chamber 211 can be rotated to dock with the storage channel, and the scooping module 212 can be used to lift and horizontally extend and scoop the racks in the storage chamber 3.

[0082] It should be noted that the extraction chamber 211 can be rotated to the side of the shovel transfer channel opening, and the shovel module 212 can be moved to the side of the shovel transfer channel opening by lifting and lowering. The shovel module 212 can be moved into the operation chamber 1 by horizontal extension and retraction, and the gripping component 7 in the operation chamber 1 can grip the plate frame on the shovel module 212.

[0083] Furthermore, it also includes a docking component 5, which is retractable and movable to receive the transfer tank 6 and drives the transfer tank 6 to rise and fall to dock with the operating cabin 1.

[0084] It should be noted that the docking component 5 can drive the transfer tank 6 to move horizontally and can also drive the transfer tank 6 to rise and dock with the operating cabin 1, so that the operating cabin 1 can be used to grab and transfer the samples inside the transfer tank 6.

[0085] Furthermore, a gripping component 7 is movable inside the operating cabin 1. The gripping component 7 can grip and pick up the plates and sample tubes transported by the transfer cabin 2 and the docking component 5; the gripping component 7 can also grip, open, and transfer the lid of the transfer tank 6.

[0086] It should be noted that the gripping component 7 can move in three dimensions within the operating chamber 1. The gripping component 7 can be used to grip and transfer the plate frame and the lid of the transfer tank 6. Furthermore, the gripping component 7 can be used to perform negative pressure suction on the sample tube, enabling the sample tube to be picked up.

[0087] Furthermore, the rotating storage assembly 32 includes a rotating frame drive module 321 and a rotating frame 322. The rotating frame drive module 321 can drive the rotating frame 322 to rotate, and the rotating frame 322 can store the plates. The rotating frame 322 includes a first basket frame 3221 and a second basket frame 3223. The first basket frames 3221 are arranged in a circumferential array, and the second basket frames 3223 are arranged between each pair of first basket frames 3221. The first basket frames 3221 and the second basket frames 3223 can support and store plates of different specifications.

[0088] It should be noted that the rotating frame drive module 321 can drive the rotating frame 322 to rotate 360 ​​degrees in the circumference, and the scooping module 212 can scoop up any plate on the rotating frame 322.

[0089] It should be noted that the liquid nitrogen cooling assembly 42 is located at the center of the rotating frame 322, and the samples on the rotating frame 322 can be stored at low temperature through the liquid nitrogen cooling assembly 42.

[0090] It should be noted that the rotating rack 322 can hold several sample boxes / plates of different sizes to accommodate different storage requirements.

[0091] It should be noted that by setting up the first basket frame 3221 and the second basket frame 3223, the first basket frame 3221 can support the double-row shelf, and the second basket frame 3223 can support and store the single-row shelf; thus improving space utilization and storage efficiency.

[0092] Furthermore, the gripping component 7 includes a three-dimensional moving support frame 71, on which a gripping lifting module 75 and a cover-moving module 74 are slidably mounted. The gripping lifting module 75 has a clamping module 72 and a suction module 73 on both sides. The gripping lifting module 75 can drive the clamping module 72 and the suction module 73 to move up and down. The clamping module 72 can grip and transfer the cover of the plate frame and the transfer tank 6, the suction module 73 can suction and transfer the sample tube, and the cover-moving module 74 can open or seal the docking channel in the operating chamber 1.

[0093] It should be noted that the operating chamber 1 is equipped with a docking channel. The docking component 5 can drive the transfer tank 6 to rise and dock with the interior of the operating chamber 1 through the docking channel to realize the sample transfer operation.

[0094] It should be noted that the three-dimensional moving support frame 71 can drive the gripping lifting module 75 and the cover-moving module 74 to slide horizontally, and can reach any position in the operating cabin 1. The gripping lifting module 75 can drive the clamping module 72 and the suction module 73 to rise and fall respectively. The cover-moving module 74 can open or seal the docking channel.

[0095] It should be noted that the clamping module 72, the suction module 73, and the cap-moving module 7 can move in the XYZ three-axis direction, thereby quickly gripping the sample tube and the plate holder. The cap-moving module 7 can open or seal the docking channel.

[0096] It should be noted that the gripping and lifting module 75 can use a conveyor belt and a rotating wheel to simultaneously drive the gripping module 72 and the suction module 73 to rise and fall. When the gripping module 72 rises, the suction module 73 is in a downward state, which facilitates the lifting and lowering of the gripping module 72 and the suction module 73.

[0097] Furthermore, the gripping module 72 includes a rotating frame module 721, a gripper module 722, and a clamping plate 723; the rotating frame module 721 is provided with the gripper module 722, and the gripper module 722 is provided with the clamping plate 723. The rotating frame module 721 can drive the gripper module 722 to rotate, the clamping plate 723 can clamp the frame, and the gripper module 722 can grip and transfer the frame and the lid of the transfer tank 6.

[0098] It should be noted that the rotating frame module 721 can be raised and lowered by rotating the rotating frame module 721, and the gripper module 722 can be rotated 360 degrees by rotating the rotating frame module 721, so as to better adapt to different working scenarios.

[0099] Preferably, the gripper module 722 can grip the plate frame, and the gripper module 722 can also grip the lid of the transfer tank 6, thereby allowing the target object to be placed at any position inside the operating cabin 1.

[0100] It should be noted that by setting the clamping plate 723 between the two sets of clamping plates, the clamping plate 723 can be used to press the plate frame, ensuring that the plate frame is pressed and fixed during placement, thus ensuring the stability of the plate frame.

[0101] Furthermore, the cover-moving module 74 includes a lifting support frame 741 and a sealing cover 742; the sealing cover 742 is mounted on the lifting support frame 741, and the lifting support frame 741 can drive the sealing cover 742 to move up and down, and can rotate to open or seal the docking channel.

[0102] It should be noted that the lifting support frame 741 can drive the sealing cover 742 to rise and fall. After the sealing cover 742 is driven down to a certain position, the sealing cover 742 can rotate to seal the channel opening, realizing integrated operations such as grabbing, picking up the pipe, and moving the cover. This saves time, eliminates the need for an additional three-dimensional cover moving mechanism, reduces the structure, and lowers costs. Example 3

[0103] Reference Figures 1-4 6 and 7-14 are the third embodiment of the present invention. Based on embodiment 1, it also includes an operation chamber 1, a transfer chamber 2, a storage chamber 3, and a cooling mechanism 4. The operation chamber 1 and the transfer chamber 2 are provided on the side of the storage chamber 3. The transfer chamber 2 can dock with the operation chamber 1 and the storage chamber 3 for sample transfer, etc. The cooling mechanism 4 can cool the storage chamber 3 and control and adjust the internal temperature of the storage chamber 3. The storage chamber 3 can store sample tubes and plates at low temperatures.

[0104] Specifically, it includes an operation chamber 1, a transfer chamber 2, a storage chamber 3, and a refrigeration mechanism 4; the operation chamber 1 and the transfer chamber 2 are located on the side of the storage chamber 3, and the transfer chamber 2 is used for sample transfer docking with the operation chamber 1 and the storage chamber 3. The refrigeration mechanism 4 is located on the storage chamber 3 and can refrigerate and control the temperature inside the storage chamber 3.

[0105] Furthermore, the refrigeration mechanism 4 includes a Stirling refrigeration component 41, which is installed on the side wall of the storage compartment 3. The Stirling refrigeration component 41 can control the temperature inside the storage compartment 3 by starting and stopping it.

[0106] It should be noted that the Stirling refrigeration unit 41 relies on the Stirling engine to achieve precise control over an ultra-wide temperature range of -20℃ to -110℃. It completes the automatic switching of operating conditions by starting and stopping the Stirling engine, and the temperature control switching logic is simple and the response is efficient.

[0107] Furthermore, the Stirling refrigeration assembly 41 includes a drive module 411 and a heat absorption module 412; the drive module 411 is connected to the heat absorption module 412, and the heat absorption module 412 is wound around the outer wall of the storage compartment 3, and the heat absorption module 412 can absorb heat and control the temperature of the storage compartment 3.

[0108] It should be noted that by wrapping the heat-absorbing module 412 around the outer wall of the storage compartment 3, the storage compartment 3 can be cooled and its heat absorbed, thereby reducing the temperature of the storage compartment 3.

[0109] Furthermore, the heat absorption module 412 includes a first heat absorption pipe 4121 and a second heat absorption pipe 4122; the first heat absorption pipe 4121 and the second heat absorption pipe 4122 can be bent and wrapped multiple times to fit against the outer wall of the storage compartment 3, and the first heat absorption pipe 4121 and the second heat absorption pipe 4122 are connected at the bottom end of the outer wall of the storage compartment 3.

[0110] It should be noted that the first heat absorption pipe 4121 is output from the port of the drive module 411 and is attached to the outer wall of the storage compartment 3 in a curved shape. At the bottom of the outer wall, the first heat absorption pipe 4121 is connected to the second heat absorption pipe 4122, and the second heat absorption pipe 4122 is attached to the outer wall of the storage compartment 3 in a curved shape from bottom to top. The second heat absorption pipe 4122 is also connected to the drive module 411.

[0111] It should be noted that the cooling of a Stirling engine is essentially a reverse Stirling cycle: through external mechanical work, the working fluid helium / hydrogen undergoes four processes in a sealed cylinder: isothermal compression and heat release, isochoric reheat, isothermal expansion and heat absorption, and isochoric cooling, thus "transferring" heat from the low-temperature end to the high-temperature end and dissipating it, thereby achieving cooling.

[0112] refer to Figures 10-13 Furthermore, the cooling mechanism 4 includes a circulating cooling component 43; the circulating cooling component 43 is disposed inside the storage chamber 3, and liquid nitrogen is disposed inside the circulating cooling component 43. The liquid nitrogen in the circulating cooling component 43 can continuously control the temperature of the sample in the storage chamber 3 with zero consumption.

[0113] It should be noted that the circulating refrigeration component 43 contains liquid nitrogen. During use, the liquid nitrogen will vaporize and then liquefy, thus eliminating the need to add additional liquid nitrogen and saving a large amount of liquid nitrogen.

[0114] Furthermore, the circulating refrigeration component 43 includes a sealed cavity 431, with a liquefaction element 432 disposed at the upper end of the sealed cavity 431 and a heat insulation element 433 disposed on the side of the liquefaction element 432; the liquefaction element 432 can liquefy vaporized liquid nitrogen, and the heat insulation element 433 can keep the liquefaction element 432 warm.

[0115] It should be noted that a liquefaction component 432 is sealed to the upper end of the sealed cavity 431. The liquefaction component 432 can liquefy the vaporized liquid nitrogen, so that it can continue to cool the sample inside the storage chamber 3.

[0116] Furthermore, the liquefaction component 432 includes liquefaction fins 4321 and a refrigeration drive module 4322; the liquefaction fins 4321 are disposed at the upper end of the sealed cavity 431, the refrigeration drive module 4322 can refrigerate the liquefaction fins 4321, and the liquefaction fins 4321 can circulate and liquefy the vaporized liquid nitrogen.

[0117] It should be noted that the refrigeration drive module 4322 is a Stirling refrigerator, and the liquefaction fins 4321 are set in multiple groups. The refrigeration drive module 4322 refrigerates the liquefaction fins 4321. The vaporized nitrogen gas encounters the liquefaction fins 4321 and is converted into liquid nitrogen, which then returns to the bottom of the sealed cavity 431 to continuously refrigerate the sample. When it vaporizes again, the vaporized nitrogen gas is converted back into liquid nitrogen by the liquefaction fins 4321. This cycle is repeated to achieve zero consumption of liquid nitrogen and eliminate the need for liquid replenishment, thus significantly saving the cost of liquid nitrogen.

[0118] It should be noted that in this embodiment, the circulating cooling component 43 can replace the liquid nitrogen cooling component 42; in this embodiment, the circulating cooling component 43 or the Stirling cooling component 41 can be set separately, and the circulating cooling component 43 and the Stirling cooling component 41 can be set simultaneously and operate at the same time. The circulating cooling component 43 or the Stirling cooling component 41 can be switched arbitrarily according to the application scenario.

[0119] Furthermore, the storage compartment 3 includes a vertical storage refrigerator 31, and a rotating storage component 32 is provided inside the vertical storage refrigerator 31; the rotating storage component 32 can rotate and store the rack and samples.

[0120] It should be noted that the first heat-absorbing pipe 4121 and the second heat-absorbing pipe 4122 are attached and wrapped around the vertical storage refrigerator 31. A thickened heat-absorbing body is also provided on the outer side of the first heat-absorbing pipe 4121 and the second heat-absorbing pipe 4122, which can be used to further keep the temperature.

[0121] Furthermore, the storage compartment 3 is equipped with an access channel; the transfer compartment 2 can access samples inside the operation compartment 1 through the access channel.

[0122] Furthermore, the transfer chamber 2 includes an extraction component 21 and a rotary sealing door component 22; the rotary sealing door component 22 is disposed on the extraction component 21, the rotary sealing door component 22 can drive the extraction component 21 to rotate, and the rotary sealing door component 22 can open or seal the access channel.

[0123] It should be noted that the extraction component 21 and the rotary sealing door component 22 can rotate simultaneously. The rotary sealing door component 22 can open or seal the access channel, and the extraction component 21 can dock with the operating compartment 1 or the storage compartment 3.

[0124] Furthermore, the extraction component 21 includes an extraction chamber 211, in which a scooping module 212 is installed. The scooping module 212 can be raised and lowered within the extraction chamber 211 and can be extended and retracted horizontally. The transfer chamber 2 is also provided with a scooping transfer channel opening, through which the scooping module 212 can dock with the storage chamber 3 or the operation chamber 1 respectively via the storage channel or the scooping transfer channel opening.

[0125] It should be noted that, under normal conditions, the shovel transfer channel opening can be sealed using a lifting sealing door. When docking is required, the lifting sealing door is opened to reduce temperature exchange.

[0126] It should be noted that the extraction chamber 211 can be rotated to dock with the storage channel, and the scooping module 212 can be used to lift and horizontally extend and scoop the racks in the storage chamber 3.

[0127] It should be noted that the extraction chamber 211 can be rotated to the side of the shovel transfer channel opening, and the shovel module 212 can be moved to the side of the shovel transfer channel opening by lifting and lowering. The shovel module 212 can be moved into the operation chamber 1 by horizontal extension and retraction, and the gripping component 7 in the operation chamber 1 can grip the plate frame on the shovel module 212.

[0128] Furthermore, it also includes a docking component 5, which is retractable and movable to receive the transfer tank 6 and drives the transfer tank 6 to rise and fall to dock with the operating cabin 1.

[0129] It should be noted that the docking component 5 can drive the transfer tank 6 to move horizontally and can also drive the transfer tank 6 to rise and dock with the operating cabin 1, so that the operating cabin 1 can be used to grab and transfer the samples inside the transfer tank 6.

[0130] Furthermore, a gripping component 7 is movable inside the operating cabin 1. The gripping component 7 can grip and pick up the plates and sample tubes transported by the transfer cabin 2 and the docking component 5; the gripping component 7 can also grip, open, and transfer the lid of the transfer tank 6.

[0131] It should be noted that the gripping component 7 can move in three dimensions within the operating chamber 1. The gripping component 7 can be used to grip and transfer the plate frame and the lid of the transfer tank 6. Furthermore, the gripping component 7 can be used to perform negative pressure suction on the sample tube, enabling the sample tube to be picked up.

[0132] Furthermore, the rotating storage assembly 32 includes a rotating frame drive module 321 and a rotating frame 322. The rotating frame drive module 321 can drive the rotating frame 322 to rotate, and the rotating frame 322 can store the plates. The rotating frame 322 includes a first basket frame 3221 and a second basket frame 3223. The first basket frames 3221 are arranged in a circumferential array, and the second basket frames 3223 are arranged between each pair of first basket frames 3221. The first basket frames 3221 and the second basket frames 3223 can support and store plates of different specifications.

[0133] It should be noted that the rotating frame drive module 321 can drive the rotating frame 322 to rotate 360 ​​degrees in the circumference, and the scooping module 212 can scoop up any plate on the rotating frame 322.

[0134] It should be noted that the liquid nitrogen cooling assembly 42 is located at the center of the rotating frame 322, and the samples on the rotating frame 322 can be stored at low temperature through the liquid nitrogen cooling assembly 42.

[0135] It should be noted that the rotating rack 322 can hold several sample boxes / plates of different sizes to accommodate different storage requirements.

[0136] It should be noted that by setting up the first basket frame 3221 and the second basket frame 3223, the first basket frame 3221 can support the double-row shelf, and the second basket frame 3223 can support and store the single-row shelf; thus improving space utilization and storage efficiency.

[0137] Furthermore, the gripping component 7 includes a three-dimensional moving support frame 71, on which a gripping lifting module 75 and a cover-moving module 74 are slidably mounted. The gripping lifting module 75 has a clamping module 72 and a suction module 73 on both sides. The gripping lifting module 75 can drive the clamping module 72 and the suction module 73 to move up and down. The clamping module 72 can grip and transfer the cover of the plate frame and the transfer tank 6, the suction module 73 can suction and transfer the sample tube, and the cover-moving module 74 can open or seal the docking channel in the operating chamber 1.

[0138] It should be noted that the operating chamber 1 is equipped with a docking channel. The docking component 5 can drive the transfer tank 6 to rise and dock with the interior of the operating chamber 1 through the docking channel to realize the sample transfer operation.

[0139] It should be noted that the three-dimensional moving support frame 71 can drive the gripping lifting module 75 and the cover-moving module 74 to slide horizontally, and can reach any position in the operating cabin 1. The gripping lifting module 75 can drive the clamping module 72 and the suction module 73 to rise and fall respectively. The cover-moving module 74 can open or seal the docking channel.

[0140] It should be noted that the clamping module 72, the suction module 73, and the cap-moving module 7 can move in the XYZ three-axis direction, thereby quickly gripping the sample tube and the plate holder. The cap-moving module 7 can open or seal the docking channel.

[0141] It should be noted that the gripping and lifting module 75 can use a conveyor belt and a rotating wheel to simultaneously drive the gripping module 72 and the suction module 73 to rise and fall. When the gripping module 72 rises, the suction module 73 is in a downward state, which facilitates the lifting and lowering of the gripping module 72 and the suction module 73.

[0142] Furthermore, the gripping module 72 includes a rotating frame module 721, a gripper module 722, and a clamping plate 723; the rotating frame module 721 is provided with the gripper module 722, and the gripper module 722 is provided with the clamping plate 723. The rotating frame module 721 can drive the gripper module 722 to rotate, the clamping plate 723 can clamp the frame, and the gripper module 722 can grip and transfer the frame and the lid of the transfer tank 6.

[0143] It should be noted that the rotating frame module 721 can be raised and lowered by rotating the rotating frame module 721, and the gripper module 722 can be rotated 360 degrees by rotating the rotating frame module 721, so as to better adapt to different working scenarios.

[0144] Preferably, the gripper module 722 can grip the plate frame, and the gripper module 722 can also grip the lid of the transfer tank 6, thereby allowing the target object to be placed at any position inside the operating cabin 1.

[0145] It should be noted that by setting the clamping plate 723 between the two sets of clamping plates, the clamping plate 723 can be used to press the plate frame, ensuring that the plate frame is pressed and fixed during placement, thus ensuring the stability of the plate frame.

[0146] Furthermore, the cover-moving module 74 includes a lifting support frame 741 and a sealing cover 742; the sealing cover 742 is mounted on the lifting support frame 741, and the lifting support frame 741 can drive the sealing cover 742 to move up and down, and can rotate to open or seal the docking channel.

[0147] It should be noted that the lifting support frame 741 can drive the sealing cover 742 to rise and fall. After the sealing cover 742 is driven down to a certain position, the sealing cover 742 can rotate to seal the channel opening, realizing integrated operations such as grabbing, picking up the pipe, and moving the cover. This saves time, eliminates the need for an additional three-dimensional cover moving mechanism, reduces the structure, and lowers costs. Example 4

[0148] Reference Figure 15This is the fourth embodiment of the present invention. Based on embodiments 1 to 3, it further includes a transfer compartment 2; the transfer compartment 2 also includes a push-pull sealing door assembly 23, which can open or seal the access channel; It should be noted that the push-pull sealing door assembly 23 in this embodiment can be used to replace the rotary sealing door assembly 22, and the push-pull sealing door assembly 23 can be used to push-pull seal the access channel.

[0149] The push-pull sealing door assembly 23 includes a screw drive module 231, a follower 232, a second sealing door 233, a support limiting member 234, and a sliding shaft 235. The two sides of the follower 232 are respectively connected to the screw drive module 231 and the second sealing door 233. The support limiting member 234 is provided with a rotatable sliding shaft 235, and the second sealing door 233 is slidably connected to the sliding shaft 235. The screw drive module 231 can drive the follower 232 to move and drive the second sealing door 233 to slide along the sliding shaft 235. The second sealing door 233 can drive the sliding shaft 235 to rotatably seal the docking channel opening.

[0150] It should be noted that the lead screw drive module 231 adopts a double helix lead screw drive module, and the threads are left-hand threads and right-hand threads; the driven member 232 adopts a push rod, and the push rod is set in two sets. One end of the two sets of push rods is movably connected to the second sealing door 233, and the other end of the two sets of push rods is set on the left-hand thread and the right-hand thread.

[0151] It should be noted that the support limiting component 234 includes a support shaft, one end of which is provided with a rotating module and the other end with a limiting frame. One end of the sliding shaft 235 is connected to the rotating module and the other end is set inside the limiting frame. There is a certain amount of movement space inside the limiting frame. The sliding shaft 235 can rotate at a certain angle through the rotating module and the angle of the sliding shaft 235 can be limited by the limiting frame. The purpose of allowing the sliding shaft 235 to rotate at a certain angle is to enable the second sealing door 233 to seal the docking channel opening.

[0152] It should be noted that the lead screw drive module 231 drives the driven member 232 to slide the second sealing door 233 along the sliding shaft 235 vertically and horizontally, and can drive the sliding shaft 235 to rotate at a certain angle. The second sealing door 233 can open or seal the access channel. Example 5

[0153] Reference Figure 16-19This is the fifth embodiment of the present invention. Based on embodiments 1 to 4, it also includes another implementation of the gripping module 72. The gripping module 72 further includes a rotating frame module 721, a flexible gripping component 725, and a second driving component 726. The flexible gripping component 725 is disposed below the rotating frame module 721, and the second driving component 726 is disposed on the flexible gripping component 725. The second driving component 726 can drive the flexible gripping component 725 to grip the plate frame or sample tube.

[0154] It should be noted that the lower end of the rotating frame module 721 is connected to a flexible clamping component 725. The flexible clamping component 725 can be driven by the second driving component 726, and the plate frame or sample tube can be clamped or released by the flexible clamping component 725.

[0155] It should be noted that in the first embodiment of the second driving member 726, the second driving member 726 includes a sliding magnet 7261 and a fixed magnet 7262. The fixed magnet 7262 is fixedly disposed on the side of the flexible gripper 725. The sliding magnet 7261 can slide up and down. When the sliding magnet 7261 and the fixed magnet 7262 are energized, they can generate magnetism, which can cause the first gripper 7251 and the second gripper 7252 to rotate inward at a small angle, thereby clamping the plate holder or sample tube.

[0156] Furthermore, the gripping module 72 also includes a spring-back member 727, which is disposed on the flexible gripping member 725. The spring-back member 727 drives the flexible gripping member 725 to expand and spring back.

[0157] It should be noted that in the first embodiment of the flexible gripper 725, the flexible gripper 725 includes a first gripper 7251, a second gripper 7252, and a support plate 7253, with the support plates symmetrically arranged. The first gripper 7251 and the second gripper 7252 are respectively arranged below the two sets of support plates 7253. The spring member 727 is arranged between the first gripper 7251 and the second gripper 7252. The first gripper 7251 and the second gripper 7252 can be driven to squeeze inward by the second driving member 726, which can clamp the plate holder or sample tube. When it is necessary to place the plate holder or sample tube, the magnet is fixed by the sliding magnet sliding upward principle, and the spring member 727 drives the first gripper 7251 and the second gripper 7252 to expand and return to the initial position.

[0158] It should be noted that the spring-loaded spring 727 can be a spring-loaded component.

[0159] It should be noted that the second embodiment of the flexible gripper 725 includes a third gripper 7254 and a fourth gripper 7255, which can clamp or release the plate holder and sample tube.

[0160] It should be noted that in the second embodiment of the second driving component 726, the expansion module 7263 and the stop module 7264 are provided at the upper and lower ends of the expansion module 7263. The stop module 7264 can stop the expansion module 7263. When the expansion module 7263 is powered on, the expansion module 7263 can expand the third gripper 7254 and the fourth gripper 7255 inward to form a clamping force, so that the third gripper 7254 and the fourth gripper 7255 can clamp the plate frame or sample tube, and vice versa. Example 6

[0161] Reference Figures 19-23 This is the sixth embodiment of the present invention. Based on embodiments 1 to 5, this embodiment also includes a storage compartment 3 and a refrigeration mechanism 4. The refrigeration mechanism 4 is disposed on the storage compartment 3 and can refrigerate and control the temperature inside the storage compartment 3.

[0162] Furthermore, the refrigeration mechanism 4 includes a Stirling refrigeration component 41, which is installed on the side wall of the storage compartment 3. The Stirling refrigeration component 41 can control the temperature inside the storage compartment 3 by starting and stopping it.

[0163] It should be noted that the Stirling refrigeration unit 41 relies on the Stirling engine to achieve precise control over an ultra-wide temperature range of -20℃ to -110℃. It completes the automatic switching of operating conditions by starting and stopping the Stirling engine, and the temperature control switching logic is simple and the response is efficient.

[0164] Furthermore, the Stirling refrigeration assembly 41 includes a drive module 411 and a heat absorption module 412; the drive module 411 is connected to the heat absorption module 412, and the heat absorption module 412 is wound around the outer wall of the storage compartment 3, and the heat absorption module 412 can absorb heat and control the temperature of the storage compartment 3.

[0165] Furthermore, the heat absorption module 412 includes a first heat absorption pipe 4121 and a second heat absorption pipe 4122; the first heat absorption pipe 4121 and the second heat absorption pipe 4122 can be bent and wound multiple times to fit against the side wall of the storage compartment 3, and the first heat absorption pipe 4121 and the second heat absorption pipe 4122 are connected at the bottom end of the side wall of the storage compartment 3.

[0166] Furthermore, the storage chamber 3 includes a liquid nitrogen tank 33, and a rotating storage component 32 is provided inside the liquid nitrogen tank 33; the rotating storage component 32 can rotatably store the plate frame and the sample; the liquid nitrogen tank 33 is filled with liquid nitrogen, which can be used to cool the sample on the rotating storage component 32.

[0167] It should be noted that the liquid nitrogen tank 33 is a sealed cylindrical structure, and a plate rack extraction channel is provided on the liquid nitrogen tank 33. The plate rack extraction channel is equipped with a sealing module inside, which can seal the plate rack extraction channel.

[0168] It should be noted that the first heat absorption tube 4121 and the second heat absorption tube 4122 are bent and attached to the side wall inside the liquid nitrogen tank 33, and the first heat absorption tube 4121 and the second heat absorption tube 4122 can cover the periphery of the rotating storage component 32, and can cool and absorb heat from the rotating storage component 32.

[0169] It should be noted that in this example, the cooling method uses liquid nitrogen cooling and Stirling cooling component 41. The two cooling methods can be switched or run simultaneously. After the liquid nitrogen in the liquid nitrogen tank 33 is consumed, the Stirling cooling component 41 can be switched to cool.

[0170] It should be noted that the cryogenic refrigeration technology of the Stirling refrigeration component 41, in conjunction with the liquid nitrogen immersion contact of the partition layer, can greatly reduce liquid nitrogen consumption without affecting the positive pressure and oxygen-free state inside the tank, thus ensuring the safety of biological agents.

[0171] It is important to note that the constructions and arrangements of this application shown in several different exemplary embodiments are merely illustrative. Although only a few embodiments are described in detail in this disclosure, those who consult this disclosure will readily understand that many modifications are possible (e.g., changes in the size, dimensions, structure, shape, and proportions of various elements, as well as parameter values ​​(e.g., temperature, pressure, etc.), mounting arrangements, use of materials, color, orientation, etc.) without substantially departing from the novel teachings and advantages of the subject matter described in this application). For example, an element shown as integrally formed may be composed of multiple parts or elements, the position of elements may be inverted or otherwise altered, and the nature or number or position of discrete elements may be changed or altered. Therefore, all such modifications are intended to be included within the scope of the invention. The order or sequence of any process or method steps may be changed or rearranged according to alternative embodiments. In the claims, any "device plus function" clause is intended to cover the structure described herein that performs the function, and not only structurally equivalent but also equivalent in structure. Other substitutions, modifications, alterations, and omissions may be made in the design, operation, and arrangement of the exemplary embodiments without departing from the scope of the invention. Therefore, the present invention is not limited to the specific embodiments, but extends to various modifications that still fall within the scope of the appended claims.

[0172] Furthermore, in order to provide a concise description of exemplary embodiments, not all features of actual embodiments (i.e., those features that are not relevant to the best mode of carrying out the invention as currently considered, or those features that are not relevant to implementing the invention) may be omitted.

[0173] It should be understood that numerous specific implementation decisions can be made during the development of any practical implementation, such as in any engineering or design project. Such development efforts may be complex and time-consuming, but for those skilled in the art who benefit from this disclosure, the development effort will be a routine work of design, manufacturing, and production without requiring much experimentation.

[0174] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all such modifications or substitutions should be covered within the scope of the claims of the present invention.

Claims

1. A biological sample intelligent storage system, characterized in that: It includes an operation chamber (1), a transfer chamber (2), a storage chamber (3), and a refrigeration mechanism (4); the operation chamber (1) and the transfer chamber (2) are arranged on the side of the storage chamber (3). The transfer chamber (2) is used to transfer and dock samples between the operation chamber (1) and the storage chamber (3). The refrigeration mechanism (4) is arranged on the storage chamber (3) and can refrigerate and control the temperature inside the storage chamber (3).

2. The intelligent biological sample storage system as described in claim 1, characterized in that: The refrigeration mechanism (4) includes a Stirling refrigeration component (41), which is installed on the side wall of the storage compartment (3). The Stirling refrigeration component (41) can control the temperature inside the storage compartment (3) by starting and stopping.

3. The intelligent biological sample storage system as described in claim 2, characterized in that: The Stirling refrigeration assembly (41) includes a drive module (411) and a heat absorption module (412); the drive module (411) is connected to the heat absorption module (412), the heat absorption module (412) is wound around the outer wall of the storage compartment (3), and the heat absorption module (412) can absorb heat and control the temperature of the storage compartment (3).

4. The intelligent biological sample storage system as described in claim 3, characterized in that: The heat absorption module (412) includes a first heat absorption tube (4121) and a second heat absorption tube (4122); the first heat absorption tube (4121) and the second heat absorption tube (4122) can be bent and wrapped multiple times to fit on the side wall of the storage compartment (3), and the first heat absorption tube (4121) and the second heat absorption tube (4122) are connected at the bottom end of the side wall of the storage compartment (3).

5. The intelligent biological sample storage system as described in claim 1, characterized in that: The refrigeration mechanism (4) further includes a liquid nitrogen refrigeration component (42); the liquid nitrogen refrigeration component (42) is located inside the storage chamber (3), and the liquid nitrogen refrigeration component (42) can control the temperature of the sample inside the storage chamber (3).

6. The intelligent biological sample storage system as described in claim 5, characterized in that: The liquid nitrogen refrigeration assembly (42) includes a liquid nitrogen cylinder (421) and a liquid supply pipeline control module (422); the liquid supply pipeline control module (422) is located at the upper end of the storage compartment (3), and the liquid supply pipeline control module (422) can add liquid to the liquid nitrogen cylinder (421) through the pipeline.

7. The intelligent biological sample storage system as described in claim 1, characterized in that: The refrigeration mechanism (4) includes a circulating refrigeration component (43); the circulating refrigeration component (43) is located inside the storage chamber (3), and liquid nitrogen is provided inside the circulating refrigeration component (43). The liquid nitrogen in the circulating refrigeration component (43) can continuously control the temperature of the sample in the storage chamber (3) with zero consumption.

8. The intelligent biological sample storage system as described in claim 7, characterized in that: The circulating refrigeration component (43) includes a sealed cavity (431), a liquefaction element (432) is provided at the upper end of the sealed cavity (431), and a heat insulation element (433) is provided on the side of the liquefaction element (432); the liquefaction element (432) can liquefy vaporized liquid nitrogen, and the heat insulation element (433) can keep the liquefaction element (432) warm.

9. The intelligent biological sample storage system as described in claim 8, characterized in that: The liquefaction component (432) includes liquefaction fins (4321) and a refrigeration drive module (4322); the liquefaction fins (4321) are disposed on the upper end of the sealed cavity (431), the refrigeration drive module (4322) can refrigerate the liquefaction fins (4321), and the liquefaction fins (4321) can circulate and liquefy vaporized liquid nitrogen.

10. The intelligent biological sample storage system according to any one of claims 1 to 9, characterized in that: The storage compartment (3) includes a vertical storage refrigerator (31), and a rotating storage component (32) is provided inside the vertical storage refrigerator (31); the rotating storage component (32) can rotate the rack and samples for storage.

11. The intelligent biological sample storage system according to any one of claims 1 to 9, characterized in that: The storage compartment (3) is provided with an access channel; the transfer compartment (2) can access the samples inside the operation compartment (1) through the access channel.

12. The intelligent biological sample storage system as described in claim 11, characterized in that: The transfer chamber (2) includes an extraction component (21) and a rotating sealing door component (22); the rotating sealing door component (22) is disposed on the extraction component (21), the rotating sealing door component (22) can drive the extraction component (21) to rotate, and the rotating sealing door component (22) can open or seal the access channel.

13. The intelligent biological sample storage system as described in claim 12, characterized in that: The extraction component (21) includes an extraction chamber (211), in which a shovel module (212) is provided. The shovel module (212) can be raised and lowered and can be horizontally extended and retracted within the extraction chamber (211). The transfer chamber (2) is also provided with a shovel transfer channel. The shovel module (212) can be docked with the storage chamber (3) or the operation chamber (1) through the access channel or the shovel transfer channel.

14. The intelligent biological sample storage system according to any one of claims 1 to 9, characterized in that: It also includes a docking component (5), which is retractable and movable to receive the transfer tank (6) and drives the transfer tank (6) to rise and fall to dock with the operating cabin (1).

15. The intelligent biological sample storage system as described in claim 14, characterized in that: The operating cabin (1) is equipped with a gripping component (7), which can grip and pick up the plates and sample tubes transported by the transfer cabin (2) and docking component (5); the gripping component (7) can also grip, open and transfer the lid of the transfer tank (6).

16. The intelligent biological sample storage system as described in claim 10, characterized in that: The rotating storage component (32) includes a rotating frame drive module (321) and a rotating frame (322). The rotating frame drive module (321) can drive the rotating frame (322) to rotate. The rotating frame (322) can store the racks. The rotating frame (322) includes a first basket rack (3221) and a second basket rack (3223). The first basket racks (3221) are arranged in a circumferential array, and a second basket rack (3223) is arranged between each pair of first basket racks (3221). The first basket racks (3221) and the second basket racks (3223) can support and store racks of different specifications.

17. The intelligent biological sample storage system as described in claim 15, characterized in that: The gripping component (7) includes a three-dimensional moving support frame (71), on which a gripping lifting module (75) and a cover-moving module (74) are slidably arranged. On both sides of the gripping lifting module (75) are a clamping module (72) and a suction module (73). The gripping lifting module (75) can drive the clamping module (72) and the suction module (73) to lift and lower. The clamping module (72) can grip and transfer the lid of the plate frame and the transfer tank (6). The suction module (73) can suction and transfer the sample tube. The cover-moving module (74) can open or seal the docking channel in the operating chamber (1).

18. The intelligent biological sample storage system as described in claim 17, characterized in that: The gripping module (72) includes a rotating frame module (721), a gripper module (722), and a clamping plate (723). The rotating frame module (721) is provided with a gripper module (722), and the gripper module (722) is provided with a clamping plate (723). The rotating frame module (721) can drive the gripper module (722) to rotate. The clamping plate (723) can clamp the frame. The gripper module (722) can grab and transfer the frame and the lid of the transfer tank (6).

19. The intelligent biological sample storage system as described in claim 17, characterized in that: The cover-moving module (74) includes a lifting support frame (741) and a sealing cover (742); the sealing cover (742) is mounted on the lifting support frame (741), and the lifting support frame (741) can drive the sealing cover (742) to move up and down, and can rotate to open or seal the docking channel.

20. The intelligent biological sample storage system as described in claim 12, characterized in that: The transfer compartment (2) also includes a push-pull sealing door assembly (23), which can open or seal the access channel; The push-pull sealing door assembly (23) includes a screw drive module (231), a follower (232), a second sealing door (233), a support limiter (234), and a sliding shaft (235). The two sides of the follower (232) are respectively connected to the screw drive module (231) and the second sealing door (233). The support limiter (234) is provided with a rotatable sliding shaft (235). The second sealing door (233) is slidably connected to the sliding shaft (235). The screw drive module (231) can drive the follower (232) to move and drive the second sealing door (233) to slide along the sliding shaft (235). The second sealing door (233) can drive the sliding shaft (235) to rotatably seal the docking channel opening.

21. The intelligent biological sample storage system as described in claim 17, characterized in that: The gripping module (72) further includes a rotating frame module (721), a flexible gripping component (725), and a second driving component (726); the flexible gripping component (725) is provided below the rotating frame module (721), and the second driving component (726) is provided on the flexible gripping component (725). The second driving component (726) can drive the flexible gripping component (725) to grip the plate frame or sample tube.

22. The intelligent biological sample storage system as described in claim 21, characterized in that: The clamping module (72) further includes a spring-loaded component (727), which is disposed on the flexible clamping component (725). The spring-loaded component (727) drives the flexible clamping component (725) to expand and spring back.

23. The intelligent biological sample storage system as described in claim 4, characterized in that: The storage chamber (3) also includes a liquid nitrogen tank (33), and a rotating storage component (32) is provided inside the liquid nitrogen tank (33); the rotating storage component (32) can rotatably store the plate frame and the sample; the liquid nitrogen tank (33) is provided with liquid nitrogen, which can be used to cool the sample on the rotating storage component (32).

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