Continuous production method and system for producing taurine by means of ethylene oxide
Patent Information
- Application Number
- CN202610781379.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-06-02
- Publication Date
- 2026-09-25
AI Technical Summary
现有间歇式生产方法存在诸多弊端:全程依赖人工分步添加反应物料,操作繁琐,生产效率低;反应程度受人工因素影响大,反应过程的反应参数把控难度大,不同生产批次间产物质量均一性差;且环氧乙烷属于危险化学原料,依赖人工多次加料存在较大的安全隐患;同时,生产设备未设置冗余备份,一旦发生反应设备故障易导致全线停产,生产稳定性与连续性得不到保障,难以满足现代化大规模工业化连续生产要求,延长生产周期
[0012]与现有技术相比,本发明的优点在于:本发明提供一种高可靠连续化环氧乙烷法生产牛磺酸的工艺及系统,通过全流程连续化设计、一主一从比例联动控制、全节点串联双流量方块冗余配置、对反应参数检测控制,关联前后反应,实现牛磺酸合成全程自动化、连续化、稳定化生产,彻底解决传统工艺人工依赖度高、生产效率低、运行可靠性差、安全风险大的问题。
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Figure CN122810032A_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of pharmaceutical preparation technology, specifically relating to a method and system for producing taurine. Background Technology
[0002] The current ethylene oxide process for producing taurine generally employs a single-reactor batch production process. The core flow is as follows: first, sodium bisulfite is prepared to a specified volume-to-mass ratio concentration; then, liquid alkali and ethylene oxide are added to complete the first step of the reaction; this is followed by the continuous addition of sodium bisulfite and ethylene oxide to complete a six-step cyclic reaction. Subsequent steps involve droplet monitoring, replenishment of ethylene oxide, and adjustment of the reaction endpoint with liquid alkali to complete the final reaction. This current batch production method has several drawbacks: it relies entirely on manual, step-by-step addition of reactants, resulting in cumbersome operation and low production efficiency; the reaction degree is greatly affected by human factors, making it difficult to control reaction parameters and resulting in poor product quality uniformity between different production batches; furthermore, ethylene oxide is a hazardous chemical, and relying on multiple manual additions poses significant safety hazards; additionally, the production equipment lacks redundancy backups, making it prone to complete shutdowns in the event of equipment failure, compromising production stability and continuity, failing to meet the requirements of modern large-scale industrial continuous production, and extending the production cycle. Summary of the Invention
[0003] In view of the existing intermittent production method of taurine from ethylene oxide, the present invention provides a continuous production method for taurine from ethylene oxide. The method adopts a continuous process design, designs multiple reaction units, precisely controls the reaction parameters of multiple reaction units, and correlates the reaction parameters of the preceding and following reaction units to achieve stable and continuous taurine production. The process no longer requires the addition of materials manually.
[0004] Another objective of this invention is to design a continuous production system for the continuous production of taurine from ethylene oxide, thereby ensuring the implementation of the continuous production method.
[0005] The technical solution adopted in this invention is: a continuous production method for taurine using the ethylene oxide process, comprising, Step 1: Preparation of raw materials: The raw materials include sodium bisulfite, liquid alkali, and ethylene oxide. Sodium bisulfite is prepared into an aqueous solution with a mass concentration of 42-43%. Step 2: Buffer Preparation: Mix sodium bisulfite solution with liquid alkali to prepare a buffer solution. Heat the buffer solution to maintain a temperature of 70-75℃. Adjust the flow rate of the liquid alkali to stabilize the pH of the buffer solution at 5.0-5.2. Control the self-circulation flow rate of the buffer solution to be no less than 50 m³ / h. 3 / H; Step 3, First Addition Reaction: The buffer solution is mixed with ethylene oxide to carry out the addition reaction. The nucleophilic attack of the bisulfite ion on the three-membered ring of ethylene oxide causes the epoxy ring to open, forming a sulfonate. The reaction is carried out with excess sodium bisulfite. The flow rate of the buffer solution is controlled at 1.2-1.5 m. 3 / H, the ethylene oxide flow rate is controlled at 0.3-0.6m³. 3 / H, the self-circulation flow rate of the reaction mixture is controlled at 80m³ / H. 3 / H, the concentration of sodium bisulfite in the reaction mixture is controlled at 1.0-2.5 kmol / m³, the reaction is exothermic, a self-circulating reaction mixture is established, the reaction mixture is cooled during the self-circulation process to maintain the reaction temperature at 70-75℃, the pH of the reaction process is controlled to be stable at 5.9-6.3 by adding liquid alkali to the reaction mixture, the reaction pressure is <0.1MPa, and the reaction time is 8-13 hours; Step 4, Second Addition Reaction: The reactants from the first addition reaction are subjected to a deep reaction with the replenished ethylene oxide. The flow rate of the reactants from the first addition reaction is 1.2-1.5 m³ / s. 3 / H, ethylene oxide flow rate is 0.3-0.6m³ / h. 3 / H, the self-circulation flow rate of the reaction mixture for the second addition reaction is controlled at 80m. 3 / H, the concentration of sodium bisulfite in the reaction mixture is controlled at 0.3-0.5 kmol / m³, a self-circulation of the reaction mixture is established, the reaction mixture is cooled during the self-circulation process to maintain the reaction temperature at 70-75℃, liquid alkali is added to the mixture to adjust the pH to 6.2-6.3, the reaction pressure is <0.1 MPa, and the reaction time is 2-5 hours; Step 5, Alkali Stabilization Reaction: Liquid alkali is added dropwise to the reactants after the second addition reaction to neutralize and convert the excess reactive sodium bisulfite, inhibit the acidolysis of sodium hydroxyethyl sulfonate, terminate the reaction, and lock the reaction endpoint in terms of quality. The flow rate of the reactants in the second addition reaction is controlled at 1.5-1.8 m³ / H. A self-circulating reaction mixture is established. During the self-circulation process, the reaction mixture is cooled to maintain the reaction temperature at 70℃-75℃, pH at 11, reaction pressure <0.1 MPa, and reaction time at 0.5-1 hour.
[0006] Preferably, in step three, the mass concentration of sodium hydroxyethyl sulfonate in the material after the first addition reaction is 45-50%; in step four, the mass concentration of sodium hydroxyethyl sulfonate in the material after the second addition reaction is 50-52%.
[0007] Preferably, both the first addition reaction and the second addition reaction are reactions in which sodium bisulfite is in excess. Potential iodine drops are performed during the reaction process to ensure that sodium bisulfite is in excess. Specifically, 30-60 drops of potential iodine are performed in the first addition reaction and 5-8 drops in the second addition reaction.
[0008] A continuous production system for producing taurine using the ethylene oxide process includes a sodium bisulfite feed tank, a liquid alkali feed tank, an ethylene oxide storage tank, a sodium bisulfite mixing tank, a buffer unit, a first addition reaction unit, a second addition reaction unit, and an alkali stabilization reaction unit. The sodium bisulfite feed tank is connected to the sodium bisulfite mixing tank by pipeline, and the sodium bisulfite mixing tank is externally connected to a water supply pipeline. The buffer unit includes a buffer tank, a sodium bisulfite mixing tank, and a liquid alkali raw material tank, which are respectively connected to the buffer tank. Dual flow meters are connected in series in the two connecting pipelines to monitor and adjust the feed flow rates of the two materials in real time. The dual flow meter for liquid alkali automatically adjusts the flow rate of liquid alkali according to the process ratio and the ratio of sodium bisulfite to liquid alkali, following the flow rate of the sodium bisulfite solution. A buffer self-circulation pipeline is set in the delivery pipeline of the buffer tank. A thermometer, a pH meter, and a heat exchanger for heating the buffer are installed in the buffer self-circulation pipeline. Dual flow meters are connected in series in the delivery pipeline of the buffer tank to monitor and adjust the discharge flow rate of the buffer. The first addition reaction unit includes a first continuous reaction vessel. The buffer tank, the ethylene oxide storage tank, and the liquid alkali raw material tank are respectively connected to the first continuous reaction vessel. Dual flow meters are connected in series in the three connecting pipelines to monitor and adjust the feed flow rates of the three materials in real time. The dual flow meters for ethylene oxide automatically adjust the amount of ethylene oxide added according to the process ratio and reaction ratio, following the flow rate of the buffer. A first reaction liquid self-circulation pipeline is set in the delivery pipeline of the first continuous reaction vessel. A heat exchanger, a thermometer, a dual pH meter, and a dual online titrator are installed in series in the first reaction liquid self-circulation pipeline for heat exchange and cooling of the first reaction liquid. The dual flow meters are connected in series in the delivery pipeline of the first continuous reaction vessel to monitor and adjust the discharge flow rate of the first reaction liquid. The second addition reaction unit includes a second continuous reactor. The first continuous reactor, the ethylene oxide storage tank, and the liquid alkali raw material tank are respectively connected to the second continuous reactor. Dual flow meters are connected in series in the three connecting pipelines to monitor and adjust the feed flow rates of the three materials in real time. The dual flow meters for ethylene oxide automatically adjust the amount of ethylene oxide added according to the process ratio and the depth of reaction ratio, following the flow rate of the first reaction liquid. A second reaction liquid self-circulation pipeline is set in the conveying pipeline of the second continuous reactor. A heat exchanger, a thermometer, a dual pH meter, and a dual online titrator are installed in series in the second reaction liquid self-circulation pipeline for heat exchange and cooling of the second reaction liquid. The dual flow meters are connected in series in the conveying pipeline of the second continuous reactor to monitor and adjust the discharge flow rate of the second reaction liquid. The alkali stabilization reaction unit includes an alkali stabilization reactor, a second continuous reactor, and a liquid alkali raw material tank, which are respectively connected to the alkali stabilization reactor. Dual flow meters are connected in series in the two connecting pipelines to monitor and adjust the feed flow rates of the two materials in real time. The dual flow meters for liquid alkali automatically adjust the amount of liquid alkali added according to the process ratio and the flow rate of the second reaction liquid. The alkali stabilization reactor is equipped with a self-circulating pipeline for the alkali stabilization reaction liquid in its conveying pipeline. A heat exchanger, a thermometer, a dual pH meter, and a dual online titrator are installed in series in the self-circulating pipeline for the alkali stabilization reaction liquid in the reactor. Dual flow meters are connected in series in the conveying pipeline for the alkali stabilization reactor to monitor and adjust the discharge flow rate of the alkali stabilization reaction liquid.
[0009] Preferably, the sodium bisulfite raw material tank and the liquid alkali raw material tank are each equipped with a self-circulating pipeline in the conveying pipeline, and a circulating pump is installed in the self-circulating pipeline. The sodium bisulfite raw material tank and the liquid alkali raw material tank are each connected in series in the conveying pipeline to monitor the feed flow rate of the two materials in real time.
[0010] Preferably, a semi-finished product transfer unit is further provided between the first addition reaction unit and the second addition reaction unit. The semi-finished product transfer unit includes a semi-finished product transfer kettle. A dual pH meter and a dual online titrator are connected in series in the discharge pipeline of the semi-finished product transfer kettle for secondary online detection to determine the residual content of sodium bisulfite in the first reaction solution. A dual flow meter is installed in series in the conveying pipeline of the semi-finished product transfer kettle.
[0011] Specifically, the dual-flow block includes two sets of flow meters and flow regulating valves.
[0012] Compared with the prior art, the advantages of the present invention are as follows: The present invention provides a highly reliable continuous process and system for producing taurine using ethylene oxide. Through continuous design of the entire process, one master and one slave proportional linkage control, redundant configuration of dual flow blocks in series at all nodes, detection and control of reaction parameters, and correlation of pre- and post-reaction reactions, the present invention achieves fully automated, continuous, and stable production of taurine synthesis, and completely solves the problems of high dependence on manual labor, low production efficiency, poor operational reliability, and high safety risks of traditional processes. Attached Figure Description
[0013] Figure 1 This is a flowchart of the addition reaction in an embodiment of the present invention; Figure 2 This is a flowchart of the buffer unit in an embodiment of the present invention; Figure 3 This is a flowchart of the first addition reaction unit in an embodiment of the present invention; Figure 4 This is a flowchart of the second addition reaction unit in an embodiment of the present invention. Detailed Implementation
[0014] The present invention will be further described in detail below with reference to the embodiments. The embodiments are exemplary and intended to explain the present invention, but should not be construed as limiting the present invention.
[0015] This embodiment relates to a continuous production method for producing taurine using the ethylene oxide process. The production process, reaction procedure, and parameters are described in detail below.
[0016] I. Preparation of the liquid material 1. Preparation of sodium bisulfite (also referred to as sodium bisulfite in this article): composition of the solution: content 42%-43% (g / ml); temperature: room temperature sodium bisulfite aqueous solution; no chemical reaction.
[0017] 2. Liquid alkali raw material: composition of liquid: 32% (by weight), temperature: room temperature, sodium hydroxide aqueous solution.
[0018] 3. Ethylene oxide: Liquid composition: 99.95% (by weight), temperature < 6℃.
[0019] II. Buffer Preparation Buffer solution composition: a mixture of sodium bisulfite and liquid alkali, with a sodium bisulfite concentration of 4.132 kmol / m³; Figure 2The feed solutions from the sodium sulfite preparation tank and the liquid alkali raw material tank are pumped in via centrifugal pumps. Flow meters and flow control valves are installed on the delivery pipelines. All delivery pipelines have self-circulating systems. This buffer solution preparation process involves no chemical reaction. The buffer unit is equipped with a temperature control unit and a pH control unit. The purpose of this buffer solution preparation process is to thoroughly mix the two feed solutions and automatically control the temperature according to the process card requirements: 70-75℃ and pH 5.0-5.2, which are the acid-base conditions required for the subsequent addition reaction.
[0020] Automatic control loop: Buffer pH control logic: Sodium bisulfite flow rate is manually set according to production requirements. Liquid alkali addition is automatically adjusted by PID control based on the pH process setting (5.0-5.2).
[0021] Buffer temperature control logic: The buffer unit is heated by a plate heat exchanger. The heat medium is 0.2MPa saturated steam. The plate heat exchanger circuit is equipped with an automatic steam regulating valve. The cold medium is the buffer solution (a mixture of sodium bisulfite and liquid alkali).
[0022] Temperature control logic: The steam consumption is automatically adjusted by PID according to the process card (temperature control at 70-75℃).
[0023] Self-circulation flow rate and circulation time: The self-circulation flow rate is controlled at no less than 50 m³ / H, and the initial start-up circulation mixing time is no less than 10 minutes.
[0024] III. First Addition Reaction like Figure 3 The buffer unit buffer solution is pumped into the first reaction vessel, and after establishing the circulation, it enters ethylene oxide for addition reaction. This unit is equipped with temperature, pH, automatic potentiometric titrator, and flow detection and control loop.
[0025] Reaction conditions and process control points: Temperature 70℃-75℃, pH 5.9-6.3, 30-60 drops of potentiometric iodine, buffer flow rate 1.2-1.5m³. 3 / H, ethylene oxide flow rate 0.3-0.6m 3 / H. Circulation volume 80m 3 / H; reaction pressure <0.1MPa, reaction time 8-13 hours. Sodium bisulfite concentration in the reaction mixture is 1.0-2.5kmol / m³. 3 (This reaction is a reaction with excess sodium sulfite).
[0026] Control loop: A. Temperature control: This addition reaction is exothermic, and the temperature is controlled by cooling water at the process temperature of 70-75℃.
[0027] B. pH Control: This reaction involves the nucleophilic attack of the bisulfite ion on the three-membered ring of ethylene oxide, leading to ring opening and the formation of sulfonate. The reaction is carried out under slightly acidic conditions. The pH process card maintains the pH between 5.9 and 6.3.
[0028] C. Buffer flow control is interlocked by the level of the first addition reactor.
[0029] D. Ethylene oxide flow control is interlocked with an automatic potentiometric dropper.
[0030] E. Liquid alkali flow rate is an emergency procedure that is activated to correct and control the pH level when it becomes too low.
[0031] F. Initial Start-up Reaction: Once the reaction solution of the first addition reaction has completed and met the process requirements, and the downstream second addition reactor is ready for feeding, feed is supplied to the second addition reactor.
[0032] 1. The chemical reaction equation for the first-order addition reaction.
[0033]
[0034] 2. Principle of automatic potentiometric titration: I2+ 2NaSO3→2NaI + Na2S4O6 or NaHSO3+ I2+ HO → NaHSO4+ 2HI.
[0035] 3. Composition of materials in the first addition reactor Addition solution (sodium hydroxyethyl sulfonate) 45-50%, water 45-50%, sodium bisulfite, liquid alkali, and trace amounts of ethylene glycol.
[0036] IV. Second Addition Reaction like Figure 4 The feed solution from the first addition reactor is pumped into the second addition reactor, and after circulation is established, it enters ethylene oxide for the addition reaction. This unit is equipped with temperature, pH, automatic potentiometric titrators, and flow detection and control loops. This reaction is a deep reaction of the previous process. Reaction conditions and process control points: Temperature 70℃-75℃, pH 6.2-6.3, iodine drop volume 5-8 drops, buffer solution flow rate 1.2-1.5 m³ / H, ethylene oxide flow rate 0.3-0.6 m³ / H, circulation rate 80 m³ / H; reaction pressure <0.1 MPa, reaction time 2-5 hours. Sodium bisulfite concentration in the reaction mixture is 0.3-0.5 kmol / m³ (this reaction is a sodium bisulfite excess reaction).
[0037] Control loop: Same as the previous process.
[0038] During the initial start-up reaction, once the reaction liquid in the second addition reactor has reached the process requirements and the alkali stabilization reactor is ready for feeding, the material is fed into the alkali stabilization reactor.
[0039] The material composition of the second addition reactor is: addition solution (sodium hydroxyethyl sulfonate) 50-52%, water 45-50%, sodium bisulfite, liquid alkali, and trace amounts of ethylene glycol.
[0040] This embodiment also relates to a continuous production system for producing taurine using the ethylene oxide process, which mainly consists of: a sodium bisulfite feed tank, a liquid alkali feed tank, an ethylene oxide storage tank, a sodium bisulfite mixing tank, a buffer unit, a first addition reaction unit, a second addition reaction unit, and an alkali stabilization reaction unit.
[0041] 1. Sodium bisulfite preparation unit Sodium bisulfite is transferred from the raw material tank to the mixing tank, where it is mixed to a volume-to-mass ratio of 42%-43% aqueous solution. The prepared solution is then set aside for later use. A series dual-flow meter is installed on the pipeline from the raw material tank to the mixing tank to monitor the sodium bisulfite flow rate in real time. The data from the two flow meters are compared and verified to ensure accurate feed flow.
[0042] 2. Buffer solution preparation and pretreatment unit The system adopts a master-slave proportional linkage control mode: the prepared sodium bisulfite solution is used as the main material, the main material conveying flow rate is set, and the liquid alkali is used as the slave material. According to the preset process ratio, the liquid alkali is automatically conveyed in linkage with the flow rate of the sodium bisulfite solution, without the need to set the liquid alkali flow rate value separately, so as to achieve precise feeding of the two materials.
[0043] Dual flow meters are installed in series on the feed lines for sodium bisulfite solution and liquid alkali to monitor the feed flow rates of both materials in real time, ensuring the accuracy of the proportional linkage. The two materials enter the buffer tank simultaneously, where they are thoroughly mixed to prepare a stable buffer reaction solution. Dual flow meters are also installed in series on the discharge line of the buffer tank to precisely control the flow rate of the buffer solution delivered to the first continuous reactor, ensuring traceability and verifiability of the entire flow process.
[0044] 3. First-stage continuous addition reaction unit The buffer solution in the buffer tank is continuously fed to the first continuous reactor. Ethylene oxide, as a feedstock, is automatically and quantitatively added to the first continuous reactor according to the flow rate ratio of the buffer solution, and undergoes a continuous addition reaction with the buffer solution. This reaction is exothermic, and a self-circulating pipeline for the first reaction liquid is formed by two sets of circulating pumps, which, together with a cooling water circulation system, removes the heat of reaction in real time and maintains a stable reaction temperature. The material is fed, reacted, circulated, and discharged simultaneously in the first continuous reactor, achieving continuous operation throughout the entire process.
[0045] The feed and discharge pipelines of the first continuous reactor are equipped with series dual flow meters to monitor the inflow and outflow of materials in real time and ensure the material balance of the reaction system. Dual pH meters and dual online titrators are installed in series at the inlet and outlet of the reactor body. The two sets of detection devices operate simultaneously, and the data are compared and verified in real time. If one device fails or the data drifts, the other device is put into use immediately, and the automatic switching is uninterrupted to ensure accurate and reliable monitoring of reaction process parameters.
[0046] 4. Semi-finished product transfer and online inspection process As an alternative, the material from the first continuous reactor is continuously conveyed to a semi-finished product transfer vessel. The discharge pipeline from the semi-finished product transfer vessel undergoes a second online test using a dual online titrator and dual pH meters to accurately determine the residual sodium bisulfite content in the material. If the reaction is deemed not to have reached its endpoint, the material is continuously conveyed to the second continuous reactor for further reaction. This section of the pipeline is also equipped with a series dual flow meter to monitor the material flow rate in real time.
[0047] 5. Second-stage deep addition reaction process Material from the first continuous reactor or semi-finished product transfer reactor continuously enters the second continuous reactor. Based on online monitoring data, an appropriate amount of ethylene oxide is automatically added, without the need for sodium bisulfite (a spare sodium bisulfite pipeline is reserved for switching use as needed). The deep addition reaction continues until the reaction reaches the preset endpoint. The system structure of the second continuous reaction unit is the same as that of the first continuous reaction unit. Both the inlet and outlet pipelines of the second continuous reactor are equipped with series dual flow meters, and the flow rate is controllable throughout the process. After the reaction, liquid alkali is automatically added through linkage control to adjust the pH value of the material, completing the final adjustment reaction and obtaining taurine semi-finished product, which then enters the downstream purification and crystallization processes.
[0048] 6. Base-stabilized reaction unit The second continuous reactor is connected to the alkali stabilization reactor, which is connected to the liquid alkali pipe. Dual flow meters are connected in series in both connecting pipelines to monitor and adjust the feed flow rates of the two materials in real time. The dual flow meters for liquid alkali automatically adjust the amount of liquid alkali added according to the process ratio and the flow rate of the second reaction liquid. The alkali stabilization reactor is equipped with a self-circulating pipeline for the alkali stabilization reaction liquid in its conveying pipeline. A heat exchanger, thermometer, dual pH meters, and dual online titrators are installed in series in the self-circulating pipeline for the alkali stabilization reaction liquid in the reactor. Dual flow meters are connected in series in the conveying pipeline to monitor and adjust the discharge flow rate.
[0049] The above system core redundancy and control design Full-node flow redundancy design: All material feeding, conveying and discharging nodes are equipped with series dual flow meters. The two sets of flow meters collect data synchronously, back each other up and verify each other, and prevent the problem of flow loss due to the failure of a single flow meter. The flow data is connected to the DCS system to realize full-process automated flow monitoring.
[0050] Redundant design of power equipment: All metering pumps, circulation pumps and transfer pumps are configured in pairs, one for use and one for backup. These devices achieve automatic fault switching through the DCS system. When a single pump fails, the backup pump starts immediately without stopping for maintenance, ensuring uninterrupted continuous production.
[0051] Redundant design of testing equipment: pH meters and online titrators are installed in a dual-series configuration, with two sets of equipment testing simultaneously and data comparison and verification to avoid detection deviations. In the event of a failure of a single testing device, the backup device operates independently to ensure the accuracy and reliability of reaction parameter monitoring and endpoint determination.
[0052] Proportional linkage control design: The entire process adopts a master-slave control logic. Only the master material flow rate is set, and the slave material automatically follows the feed according to a fixed ratio. There is no need for manual multi-path adjustment, which simplifies the control logic, improves the accuracy of material proportioning, and reduces human operation error.
[0053] In addition to the above embodiments, the present invention also includes other embodiments. All technical solutions formed by equivalent transformation or equivalent substitution should fall within the protection scope of the claims of the present invention.
Claims
1. A continuous production method for taurine using ethylene oxide, characterized in that: include, Step 1: Preparation of raw materials: The raw materials include sodium bisulfite, liquid alkali, and ethylene oxide, wherein the sodium bisulfite is prepared into an aqueous solution with a mass concentration of 42-43%. Step 2: Buffer Preparation: Mix sodium bisulfite solution with liquid alkali to prepare a buffer solution. Heat the buffer solution to maintain a temperature of 70-75℃. Adjust the flow rate of the liquid alkali to stabilize the pH of the buffer solution at 5.0-5.
2. Control the self-circulation flow rate of the buffer solution to be no less than 50 m³ / h. 3 / H; Step 3, First Addition Reaction: The buffer solution is mixed with ethylene oxide to carry out the addition reaction. The nucleophilic attack of the bisulfite ion on the three-membered ring of ethylene oxide causes the epoxy ring to open, forming a sulfonate. The reaction is carried out with excess sodium bisulfite. The flow rate of the buffer solution is controlled at 1.2-1.5 m. 3 / H, the ethylene oxide flow rate is controlled at 0.3-0.6m³. 3 / H, the self-circulation flow rate of the reaction mixture is controlled at 80m³ / H. 3 / H, the concentration of sodium bisulfite in the reaction mixture is controlled at 1.0-2.5 kmol / m³, the reaction is exothermic, a self-circulating reaction mixture is established, the reaction mixture is cooled during the self-circulation process to maintain the reaction temperature at 70-75℃, the pH of the reaction process is controlled to be stable at 5.9-6.3 by adding liquid alkali to the reaction mixture, the reaction pressure is <0.1MPa, and the reaction time is 8-13 hours; Step 4, Second Addition Reaction: The reactants from the first addition reaction are subjected to a deep reaction with the replenished ethylene oxide. The flow rate of the reactants from the first addition reaction is 1.2-1.5 m³ / s. 3 / H, ethylene oxide flow rate is 0.3-0.6m³ / h. 3 / H, the self-circulation flow rate of the reaction mixture for the second addition reaction is controlled at 80m. 3 / H, the concentration of sodium bisulfite in the reaction mixture is controlled at 0.3-0.5 kmol / m³, a self-circulation of the reaction mixture is established, the reaction mixture is cooled during the self-circulation process to maintain the reaction temperature at 70-75℃, liquid alkali is added to the mixture to adjust the pH to 6.2-6.3, the reaction pressure is <0.1 MPa, and the reaction time is 2-5 hours; Step 5, Alkali Stabilization Reaction: Liquid alkali is added dropwise to the reactants after the second addition reaction to neutralize and convert the excess reactive sodium bisulfite, inhibit the acidolysis of sodium hydroxyethyl sulfonate, terminate the reaction, and lock the reaction endpoint in terms of quality. The flow rate of the reactants in the second addition reaction is controlled at 1.5-1.8 m³ / H. A self-circulating reaction mixture is established. During the self-circulation process, the reaction mixture is cooled to maintain the reaction temperature at 70℃-75℃, pH at 11, reaction pressure <0.1 MPa, and reaction time at 0.5-1 hour.
2. The continuous production method for taurine using the ethylene oxide process according to claim 1, characterized in that: Step 3: The mass concentration of sodium hydroxyethyl sulfonate in the material after the first addition reaction is 45-50%; Step 4: The mass concentration of sodium hydroxyethyl sulfonate in the material after the second addition reaction is 50-52%.
3. The continuous production method for taurine using the ethylene oxide process according to claim 1, characterized in that: Both the first and second addition reactions involve excess sodium bisulfite. Potential iodine drops are performed during the reaction to ensure an excess of sodium bisulfite. Specifically, 30-60 drops of potential iodine are applied to the first addition reaction, and 5-8 drops are applied to the second addition reaction.
4. A continuous production system for producing taurine using the ethylene oxide process, characterized in that: The system includes a sodium bisulfite raw material tank, a liquid alkali raw material tank, an ethylene oxide storage tank, a sodium bisulfite mixing tank, a buffer unit, a first addition reaction unit, a second addition reaction unit, and an alkali stabilization reaction unit. The sodium bisulfite raw material tank is connected to the sodium bisulfite mixing tank by pipeline, and the sodium bisulfite mixing tank is connected to an external water supply pipeline. The buffer unit includes a buffer tank, a sodium bisulfite mixing tank, and a liquid alkali raw material tank, which are respectively connected to the buffer tank. Dual flow meters are connected in series in the two connecting pipelines to monitor and adjust the feed flow rates of the two materials in real time. The dual flow meter for liquid alkali automatically adjusts the flow rate of liquid alkali according to the process ratio and the ratio of sodium bisulfite to liquid alkali, following the flow rate of the sodium bisulfite solution. A buffer self-circulation pipeline is set in the delivery pipeline of the buffer tank. A thermometer, a pH meter, and a heat exchanger for heating the buffer are installed in the buffer self-circulation pipeline. Dual flow meters are connected in series in the delivery pipeline of the buffer tank to monitor and adjust the discharge flow rate of the buffer. The first addition reaction unit includes a first continuous reaction vessel. The buffer tank, the ethylene oxide storage tank, and the liquid alkali raw material tank are respectively connected to the first continuous reaction vessel. Dual flow meters are connected in series in the three connecting pipelines to monitor and adjust the feed flow rates of the three materials in real time. The dual flow meters for ethylene oxide automatically adjust the amount of ethylene oxide added according to the process ratio and reaction ratio, following the flow rate of the buffer. A first reaction liquid self-circulation pipeline is set in the delivery pipeline of the first continuous reaction vessel. A heat exchanger, a thermometer, a dual pH meter, and a dual online titrator are installed in series in the first reaction liquid self-circulation pipeline for heat exchange and cooling of the first reaction liquid. The dual flow meters are connected in series in the delivery pipeline of the first continuous reaction vessel to monitor and adjust the discharge flow rate of the first reaction liquid. The second addition reaction unit includes a second continuous reactor. The first continuous reactor, the ethylene oxide storage tank, and the liquid alkali raw material tank are respectively connected to the second continuous reactor. Dual flow meters are connected in series in the three connecting pipelines to monitor and adjust the feed flow rates of the three materials in real time. The dual flow meters for ethylene oxide automatically adjust the amount of ethylene oxide added according to the process ratio and the depth of reaction ratio, following the flow rate of the first reaction liquid. The second continuous reactor is equipped with a second reaction liquid self-circulation pipeline in its conveying pipeline. A heat exchanger, a thermometer, a dual pH meter, and a dual online titrator are installed in series in the second reaction liquid self-circulation pipeline for heat exchange and cooling of the second reaction liquid. The dual flow meters are connected in series in the conveying pipeline of the second continuous reactor to monitor and adjust the discharge flow rate of the second reaction liquid. The alkali stabilization reaction unit includes an alkali stabilization reactor, a second continuous reactor, and a liquid alkali raw material tank, which are respectively connected to the alkali stabilization reactor. Dual flow meters are connected in series in the two connecting pipelines to monitor and adjust the feed flow rates of the two materials in real time. The dual flow meters for liquid alkali automatically adjust the amount of liquid alkali added according to the process ratio and the flow rate of the second reaction liquid. The alkali stabilization reactor is equipped with a self-circulating pipeline for the alkali stabilization reaction liquid in its conveying pipeline. A heat exchanger, a thermometer, a dual pH meter, and a dual online titrator are installed in series in the self-circulating pipeline for the alkali stabilization reaction liquid in the reactor. Dual flow meters are connected in series in the conveying pipeline for the alkali stabilization reactor to monitor and adjust the discharge flow rate of the alkali stabilization reaction liquid.
5. The continuous production system for producing taurine using the ethylene oxide method according to claim 4, characterized in that: The sodium bisulfite raw material tank and the liquid alkali raw material tank are each equipped with a self-circulating pipeline in the conveying pipeline. A circulation pump is installed in the self-circulating pipeline. The sodium bisulfite raw material tank and the liquid alkali raw material tank are each connected in series in the conveying pipeline to monitor the feed flow rate of the two materials in real time.
6. The continuous production system for producing taurine using the ethylene oxide method according to claim 4, characterized in that: A semi-finished product transfer unit is also provided between the first addition reaction unit and the second addition reaction unit. The semi-finished product transfer unit includes a semi-finished product transfer kettle. A dual pH meter and a dual online titrator are connected in series in the discharge pipeline of the semi-finished product transfer kettle for secondary online detection to determine the residual content of sodium bisulfite in the first reaction solution. A dual flow meter is installed in series in the conveying pipeline of the semi-finished product transfer kettle.
7. The continuous production system for producing taurine using the ethylene oxide process according to any one of claims 4, 5, and 6, characterized in that: The dual-flow block includes two sets of flow meters and flow regulating valves.