Drug delivery device

Abstract

The present technology relates to a drug delivery device to prepare one or more doses of a drug for administration to a patient, methods of assembly and / or use thereof. The patient can be a human patient or a veterinary patient. The drug delivery device can comprise one or more receptacles configured to each hold a dose of the drug, a mechanism to simultaneously adjust the amount of the drug in each of the plurality of receptacles, and an indicator to indicate a parameter other than the volume of the drug in the reservoir. The indicator can indicate a patient-related parameter corresponding to a volume of the drug appropriate for the patient based on the patient-related parameter.

Description

Technical Field

[0001] This technology relates to a drug delivery device and a method for preparing and using the drug delivery device. Background Technology

[0002] Medications are typically administered to patients in appropriate amounts (known as dosages), which can depend on any or one of many factors, such as age, weight, and medical condition. In high-stress and extremely urgent situations, such as in accident and emergency departments, preparing the appropriate dosages for administration to a patient can be quite challenging. Human error is possible in such situations. When multiple doses of a medication are required, clinicians may need to calculate the recommended amount for each dose.

[0003] For example, the dose of epinephrine administered intravenously / intraosseously to resuscitate a cardiac arrest patient is 10 mcg / kg or 0.1 ml / kg of a 1:10,000 epinephrine concentration. Vials containing different concentrations of the drug may be placed in drug storage areas, such as resuscitation carts, containing both 1:1,000 and 1:10,000 epinephrine concentrations. This can lead to confusion regarding the concentration of the drug used. For example, drawing each dose directly from a vial on a cart may cause clinicians to accidentally prepare multiple doses of different concentrations. Furthermore, errors in titration or dosage calculations can result in overdosing, with errors reaching 10 or 100 times the recommended dose. Alternatively, dosage errors can also result in underdosing, with the administered dose being 1 / 100 or 1 / 10 of the recommended dose.

[0004] Any error in dosing measurement can have consequences ranging from harmful to fatal for patients. The risks can be amplified when the patients in question are pediatric or neonatal patients, as the potentially appropriate dosing range for such patients is much wider. For example, in some cases, the dosing is calculated based on the patient's weight. Pediatric patients typically weigh less than adults, ranging from 10 kg to 70 kg, and neonates and infants weigh between 2.5 kg and 10 kg.

[0005] Besides the possibility of error, preparing each dose of medication individually can lead to delays in drug administration, potentially resulting in poor outcomes. Furthermore, the preparation of these medications currently often involves the handling of sharps. Needlestick injuries are common due to the high-pressure environment and can cause harm to clinicians, further delaying emergency drug delivery.

[0006] Technical Purpose The purpose of this technology is to provide an improved drug delivery device, an improved method for assembling a drug delivery system, and / or an improved method for preparing a ready dose of a drug. The improved device and / or method enable the preparation of doses easily, conveniently, and / or rapidly. Alternatively, the improved device and / or method enable the simultaneous preparation of doses. Alternatively, the improved device and / or method enable the preparation of doses that help prevent damage during the preparation of a given dose of the drug. Alternatively, the purpose of this technology is to provide an improved device and / or method that allows the preparation of a given dose of the drug without requiring the user to calculate the dose volume. Alternatively, the purpose of this technology is to provide an inexpensive solution for preparing multiple doses of the drug. Alternatively, the purpose of this technology is to at least provide a useful option for the public. Summary of the Invention

[0007] According to certain aspects of the present technology, a drug delivery device for preparing one or more doses of a drug for administration to a patient is provided, along with its assembly and / or method of use. The patient may be a human patient or a veterinary patient. The drug delivery device may include one or more receptacles configured to each contain a dose of the drug. The drug delivery device may further include a mechanism for simultaneously adjusting the amount of the drug in each of the plurality of receptacles. The drug delivery device may further include an indicator indicating parameters other than the volume of the drug in a reservoir. The indicator may indicate patient-related parameters corresponding to a suitable volume of the drug for the patient based on the patient-related parameters.

[0008] According to one aspect of the present invention, a drug delivery device is provided for preparing multiple doses of a drug for administration to a patient. The drug delivery device may include multiple receptacles. The drug delivery device may further include a mechanism for simultaneously adjusting the amount of the drug in each of the multiple receptacles. The drug delivery device may further include an indicator comprising a set of scale markings indicating patient-related parameters. The scale markings may be calibrated to correspond to a volume of the drug suitable for the patient based on the patient-related parameters.

[0009] In some forms, the patient-related parameters may be weight, gestational age, height, or body surface area.

[0010] In some forms, the plurality of accommodating portions may be arranged in one or more rows adjacent to each other.

[0011] In some forms, each of the receiving portions may be a syringe, which includes a barrel and a plunger.

[0012] In some forms, the mechanism may include a force distribution device configured to engage with the plungers of a plurality of syringes to expel the drug from or draw the drug into the plurality of syringes by moving the force distribution device.

[0013] In some forms, the force distribution device may include a plate. A first portion of the plate may be configured to be operated by a user during use, and a second portion of the plate may be configured to engage with the plungers of the plurality of syringes.

[0014] In some forms, the drug delivery device may include an indicator component having a first portion mounted to the force distribution device and a second portion positioned near the indicator to indicate patient-related parameters.

[0015] In some forms, the drug delivery device may include a stop to prevent the force distribution device from moving beyond its limits. Furthermore, the drug delivery device may include a stop adjustment mechanism to allow a user to adjust the position of the stop.

[0016] In some forms, the drug delivery device may include a drug-capturing section to capture the drug discharged from the plurality of receptacles.

[0017] In some forms, the drug delivery device may include a housing that accommodates the plurality of receptacles, and the drug capture portion includes a portion of the housing.

[0018] In some forms, the drug-capturing portion may comprise a container-shaped portion of the housing.

[0019] In some forms, the drug-capturing portion may comprise a fluid absorber.

[0020] In some forms, the drug delivery device may further include a reservoir configured to contain the drug. The plurality of receptacles may be fluidly connected in parallel to the reservoir to allow a dose of the drug to be transferred from the reservoir to each of the plurality of receptacles. The reservoir may include the indicator.

[0021] In some forms, the reservoir may be a syringe, which includes a barrel and a plunger.

[0022] In some forms, the cylinder may include the indicator, and the position of the plunger relative to the indicator indicates the volume of the drug in the cylinder.

[0023] According to one aspect of the present invention, a drug delivery device is provided for preparing one or more doses of a drug for administration to a patient. The drug delivery device may include a reservoir configured to contain the drug. The drug delivery device may further include one or more receptacles configured to be fluidly connected to the reservoir to allow transfer of a dose of the drug from the reservoir to each of the one or more receptacles. The reservoir may include an indicator comprising a set of graduations indicating patient-related parameters. The graduations may be calibrated to correspond to a volume of the drug suitable for the patient based on the patient-related parameters.

[0024] In some forms, the reservoir may be a syringe comprising a barrel and a plunger. The barrel may contain the indicator, and the position of the plunger relative to the indicator may indicate the volume of the drug in the barrel.

[0025] In some forms, the indicator may include a set of values ​​for the patient-related parameters that increase in the direction opposite to the volume of medication in the reservoir. In some forms, the set of values ​​for the patient-related parameters may increase in the direction in which the plunger is configured to be further inserted into the cylinder.

[0026] In some forms, the drug delivery device may include two or more receptacles, and the receptacles may be configured to be fluidly connected to the reservoir in parallel. In some forms, the two or more receptacles may be arranged adjacent to each other in one or more rows.

[0027] In some forms, each of the receiving portions may be a syringe, which includes a barrel and a plunger.

[0028] In some forms, the drug delivery device may further include a force distribution device configured to engage with the plunger of the one or more syringes to draw the drug into the one or more syringes by moving the force distribution device.

[0029] In some forms, the force distribution device may include a plate. A first portion of the plate may be configured to be operated by a user during use. A second portion of the plate may be configured to engage with the plunger of the one or more syringes.

[0030] In some forms, the drug delivery device can be configured such that the force distribution device can move along a predetermined path during use.

[0031] In some forms, the drug delivery device may further include a mounting component, to which the reservoir and / or one or more receiving portions are configured for mounting in use. In some forms, the reservoir may be configured for removable mounting to the mounting component in use.

[0032] In some forms, the guide portion of the mounting component may be configured to guide the force distribution device along the predetermined path during use. In some forms, the guide portion of the mounting component may be configured to hold the force distribution device at a predetermined angular orientation relative to the plunger of the one or more syringes during use.

[0033] In some forms, the guide portion of the mounting member may include at least one recess configured to receive at least one protrusion of the force distribution device. Alternatively, the guide portion of the mounting member may include at least one recess configured to be received by at least one notch of the force distribution device.

[0034] In some forms, the drug delivery device may further include a time display device mounted to the mounting component, enabling the user of the drug delivery device to monitor the passage of time on the time display device during use.

[0035] In some forms, the drug delivery device may further include a dose label configured to at least indicate the time interval between subsequent doses of the dose.

[0036] According to one aspect of the present technology, a method is provided for assembling a drug delivery system for preparing one or more doses of a drug for administration to a patient. The method may include marking a reservoir with an indicator comprising a set of graduations indicating patient-related parameters. The graduations may be calibrated to correspond to a volume of the drug suitable for the patient based on the patient-related parameters. The method may further include fluidly connecting the reservoir to one or more receptacles to allow a dose of the drug to be transferred from the reservoir to each of the one or more receptacles.

[0037] In some forms, the method may further include the step of engaging the force distribution device with at least a portion of the one or more receptacles to allow a user to inhale the drug into the one or more receptacles by moving the force distribution device.

[0038] In some forms, the method may further include the step of mounting the reservoir and / or the one or more receiving portions to the mounting component.

[0039] In some forms, the method may further include the step of filling at least a portion of the reservoir with the drug.

[0040] According to one aspect of the present technology, a method is provided for preparing one or more doses of a drug for administration to a patient. The method may include measuring values ​​of patient-related parameters of the patient. The method may further include initiating the transfer of the drug from a reservoir to one or more receptacles. The reservoir may be fluidly connected to the one or more receptacles in use. The method may further include monitoring an indicator of the reservoir. The indicator may include a set of graduations indicating the patient-related parameters. The graduations may be calibrated to correspond to a volume of the drug suitable for the patient based on the patient-related parameters. The method may further include terminating the transfer of the drug from the reservoir to the one or more receptacles when the indicator indicates a value of the patient-related parameter of the patient.

[0041] In some forms, the step of monitoring the indicator of the reservoir may further include monitoring the position of the plunger of the reservoir relative to the scale mark of the indicator.

[0042] In some forms, the step of initiating the transfer of the drug from the reservoir to the one or more accommodating portions may include moving the plunger of the reservoir in a direction that increases a set of values ​​of the patient-related parameters of the indicator.

[0043] In some forms, the step of initiating the transfer of the drug from the reservoir to the one or more receptacles may include removing a plunger from the respective cylinder on each of the one or more receptacles.

[0044] In some forms, the step of initiating the transfer of the drug from the reservoir to the one or more receptacles may further include applying force to a force dispensing device configured to engage with the plunger of the one or more receptacles.

[0045] In some forms, the step of applying force to the force distribution device may further include holding the force distribution device at a predetermined angular orientation relative to the plunger of the one or more receiving portions.

[0046] In some forms, the step of applying force to the force distribution device may further include moving the force distribution device along a predetermined path.

[0047] In some forms, the method may further include disengaging the force distribution device from the one or more receptacles after terminating the step of transferring the drug from the reservoir to the one or more receptacles.

[0048] In some forms, the method may further include disconnecting at least one of the one or more receptacles from the reservoir after terminating the step of transferring the drug from the reservoir to the one or more receptacles.

[0049] In some forms, the method may further include the step of monitoring the elapsed time on a time display device to identify when a subsequent dose should be administered to the patient.

[0050] According to one aspect of the present invention, a drug delivery device is provided for preparing multiple doses of a drug for administration to a patient. The drug delivery device may include multiple receptacles. The drug delivery device may further include a mechanism for simultaneously regulating the amount of the drug in each of the multiple receptacles. The drug delivery device may include a drug capturing portion for capturing the drug expelled from the multiple receptacles.

[0051] In some forms, the drug delivery device may include a housing that accommodates the plurality of receptacles, and the drug capture portion includes a portion of the housing.

[0052] In some forms, the drug-capturing portion may comprise a container-shaped portion of the housing.

[0053] In some forms, the drug-capturing portion may comprise a fluid absorber.

[0054] In some forms, the drug delivery device may further include an indicator comprising a set of scale markings indicating patient-related parameters. The scale markings may be calibrated to correspond to a volume of the drug suitable for the patient based on the patient-related parameters.

[0055] According to one aspect of the present invention, a drug delivery device is provided for preparing multiple doses of a drug for administration to a patient. The drug delivery device may include a plurality of receptacles. The drug delivery device may further include a mechanism for simultaneously adjusting the amount of the drug in each of the plurality of receptacles. Each of the receptacles may be a syringe, the syringe including a barrel and a plunger. The mechanism may include a force distribution device configured to engage with the plungers of the plurality of syringes to expel the drug from the plurality of syringes or draw the drug into the plurality of syringes by moving the force distribution device. The drug delivery device may further include a stop for preventing the force distribution device from moving beyond its limit. The drug delivery device may further include a stop adjustment mechanism to allow a user to adjust the position of the stop.

[0056] In some forms, the force distribution device may include a plate. A first portion of the plate may be configured to be operated by a user during use, and a second portion of the plate may be configured to engage with the plungers of the plurality of syringes.

[0057] In some forms, the drug delivery device may include an indicator component having a first end mounted to the force distribution device and a second end positioned near the indicator to indicate patient-related parameters.

[0058] In some forms, the drug delivery device may further include an indicator comprising a set of scale markings indicating patient-related parameters. The scale markings may be calibrated to correspond to a volume of the drug suitable for the patient based on the patient-related parameters.

[0059] Further aspects of the present technology (which should be considered in all its novel aspects) will become apparent to those skilled in the art after reading the following description which provides at least one example of the practical application of the present technology. Attached Figure Description

[0060] Referring to the following figures, one or more embodiments of the present technology will be described below by way of example only and are not intended to be limiting, in which: Figure 1 A perspective view of a drug delivery device according to the present technology in a first configuration is shown; Figure 2 It shows the second configuration Figure 1 A perspective view of the drug delivery device shown; Figure 3 A perspective view of another form of drug delivery device according to the present technology, in a first configuration, is shown; Figure 4 Showing Figure 3 The top view of the drug delivery device shown; Figure 5 It shows the second configuration Figure 3 The top view of the drug delivery device shown; Figure 6 Showing Figure 3 An exploded perspective view of the drug delivery device shown; Figure 7 It is in a containment configuration Figure 3 The diagram shows a perspective view of the drug delivery device. Figure 8 A perspective view of another form of drug delivery device according to the present technology, in a first configuration, is shown; Figure 9 It shows the second configuration Figure 8A perspective view of the drug delivery device shown; Figure 10 Demonstrated for Figure 9 The side view of the reservoir in the drug delivery device shown; and Figure 11 Demonstrated for Figure 9 A perspective view of the force distribution device in the drug delivery device shown. Detailed Implementation

[0061] 6.1. Drug delivery equipment Figures 1 to 11 A variety of drug delivery devices 100 and their components according to the present technology are shown. Figures 1 to 2 One form of the drug delivery device 100 is shown. Figures 3 to 7 A second form of the drug delivery device 100 is shown, and Figures 8 to 11 The third form of drug delivery device was demonstrated.

[0062] According to certain forms of drug delivery devices 100 of this technology, during assembly they are suitable for preparing one or more doses of a drug, and typically multiple doses of a drug. Figures 3 to 11 In the demonstrated technical form, the drug delivery device 100 is configured to prepare three doses of the drug, while Figures 1 to 2 In the illustrated embodiment, the drug delivery device 100 is configured to prepare four doses of the drug. These are merely examples, and in other embodiments, the drug delivery device 100 may be configured to prepare other numbers of doses of the drug.

[0063] Although different forms of drug delivery devices 100 are described and shown, all forms of drug delivery devices 100 are based on the principle of operating a mechanism that simultaneously adjusts the amount of drug in each of the plurality of containers 6 and uses an indicator to indicate when the amount of drug has been adjusted as needed. Therefore, the drug delivery device 100 includes a mechanism for simultaneously adjusting the amount in each of the containers 6. The indicator includes a set of scale markings indicating patient-related parameters. The scale markings are calibrated to correspond to a volume of drug suitable for the patient based on the patient-related parameters.

[0064] In some forms of this technology, for example, Figures 1 to 7 As shown, the drug delivery device 100 operates by simultaneously discharging excess drug from each of the containers 6, such that the desired dose remains in each of the containers 6. In these forms, the drug delivery device 100 includes an adjustment mechanism configured to operate to simultaneously discharge drug from each of the containers 6.

[0065] In other forms of this technology, for example, Figures 8 to 11As shown, the drug delivery device 100 operates by simultaneously drawing a desired dose of medication into each of the containers 6. In these forms, the drug delivery device 100 includes an adjustment mechanism configured to operate to simultaneously draw medication into each of the containers 6. In these forms, the drug delivery device 100 includes a reservoir 5 and one or more containers, such as three containers 6. The reservoir 5 is configured to contain medication, which can be transferred to the containers to prepare a corresponding number of doses, such as three doses. The medication is transferred from the reservoir 5 to the containers via a fluid connection, such as a conduit 7.

[0066] Further details of the components of the different forms of the drug delivery device 100 are described below.

[0067] 6.1.1. Reception Section In some forms of this technology, the drug delivery device 100 may include one or more receptacles 6, each of which is configured to contain a dose of drug. Figures 3 to 11 In an exemplary form of the technology shown, the drug delivery device 100 includes three receiving portions 6, and... Figures 1 to 2 In the illustrated form, the drug delivery device 100 includes four receptacles 6. In other forms, the drug delivery device 100 may include other numbers of receptacles 6. One receptacle 6 may be present for each dose of medicine prepared by the drug delivery device 100. Each receptacle 6 containing a single dose of medicine facilitates administration of the medicine to a patient.

[0068] Each of the containers 6 can be any container capable of holding a drug. In the illustrated form, each of the containers 6 is a syringe. Each syringe comprises a barrel 26 and a plunger 36. Each barrel 26 further comprises a tip 46 through which the drug can be expelled from or drawn into the syringe 6. In alternative forms, the containers can take the form of vials, bottles, jars, basins, etc.

[0069] In an exemplary form, as shown in the figure, the receptacles 6 may have substantially equal capacities; for example, they may be receptacles with equal lengths and equal diameters. This facilitates the preparation of doses of drug with substantially equal dose volumes and makes the drug delivery device 100 easy to use. In an alternative form, two or more of the receptacles 6 may have different dimensions and / or volumes from each other.

[0070] After adjusting the amount of drug in each of the containers 6 to prepare a dose, each dose can be administered to the patient sequentially (and depending on the drug). Any suitable route of drug administration can be used, including but not limited to intravenous, intraosseous, intramuscular, intratracheal, intranasal, oral, and / or local routes. The containers 6 can be selected to have features that make them suitable for administering doses to the patient via the selected route of administration.

[0071] In the illustrated form, the drug delivery device 100 can be configured to prepare various doses of epinephrine and to administer said doses intravenously. Therefore, the container 6 can be a syringe suitable for intravenous administration of epinephrine. For example, the tip 46 of the syringe can be configured to have a needle attached to said tip.

[0072] In this specification, unless the context clearly indicates otherwise, the term " dose "This can refer to the volume of the drug suitable for administration to a patient or the volume of the drug actually administered to the patient. In some cases using the drug delivery device 100 according to the form of this technology, there may be a difference between the volume of the drug intended for administration and the actual volume of the drug administered to the patient."

[0073] 6.1.2. Force Distribution Device In some forms, the mechanism for simultaneously adjusting the amount of drug in each of the receptacles 6 of the drug delivery device 100 may include a force distribution device 8 configured to facilitate the expulsion of the drug from or the aspiration of the drug into the receptacles 6. The force distribution device 8 allows the user to simultaneously apply force to all receptacles 6 to facilitate drug transfer.

[0074] In a technical form where the receiving part 6 is in the shape of a syringe, for example... Figures 1 to 11 As shown, the force distribution device 8 can be configured to engage with the plunger 36 in use to discharge or draw medication into the container 6 by moving the force distribution device 8 and thus by moving the plunger into or out of its respective cylinder.

[0075] The force distribution device 8 can be a component capable of transferring a force applied in a single location (e.g., by a user pushing or pulling in one location with their hand) to multiple locations (e.g., to multiple syringes). Figures 1 to 11In the illustrated embodiment, the force distribution device 8 comprises a plate. The plate may include a first portion 18 and a second portion 19 attached to the first portion 18. In some embodiments, the force distribution device 8 may be a component with an integrally connected first and second portion; for example, the force distribution device 8 may be molded as a single component. The second portion 19 may be configured to engage with the plunger 36 of the syringe containing the accommodating portion 6. For example, the second portion 19 may include a plurality of engagement portions 28, each configured to removably engage with each plunger 36. In the illustrated embodiment, the engagement portion 28 includes a surface of the force distribution device 8 configured to abut against a corresponding portion of the plunger 36, such as a flange 56 at the end of the plunger 36 remote from the barrel 26. The engagement portion 28 may include a suitable interlocking mechanism to engage the plunger, thereby allowing simultaneous movement of the syringe. For example, the engagement portion 28 may include an area of ​​the force distribution device 8 in which a slot is formed. The size and shape of each slot are suitably designed such that a portion of one of the plungers 36 can be received within the slot, thereby allowing a moving force to be transmitted to the plunger. For example, during assembly, each engagement portion 28 can be positioned substantially adjacent to one of the plunger flanges 56. In use, the force distribution device 8 can be configured via the engagement portion 28 to apply force against the plunger flange 56 when a user applies force on the first portion 18 to push or pull the force distribution device 8 in one direction, causing the plunger to move into or out of its corresponding cylinder. The force on the plunger flange 56 causes the plunger 36 to be pushed in or pulled out, thereby creating a discharge or suction force in the cylinder 26 that discharges or draws medication out of or into the receiving portion 6.

[0076] The force distribution device 8 allows the plungers 36 to be pushed or pulled substantially simultaneously and at a uniform rate, so that a dose with substantially equal dose volumes can be formed in the receiving portion 6. Simultaneous movement of the plungers 36 can be facilitated by the arrangement of the receiving portion 6 in which the plungers are arranged in parallel, with their respective tips 46 facing the same direction. In addition to the above, as shown in the illustrated form, the tips 46 can be substantially aligned with each other. This arrangement means that the force distribution device 8, having a substantially planar form, can easily engage with the plungers simultaneously. In an alternative form (not shown in any figures), the plungers of the receiving portion 6 can be arranged differently, and the force distribution device 8 can be shaped to complement the arrangement of the plungers; for example, if the plungers are arranged in an offset arrangement, the force distribution device can be shaped accordingly.

[0077] In some forms, the drug delivery device 100 may be configured such that the force distribution device 8 is movable along a predetermined path during use. In some forms, the predetermined path along which the force distribution device 8 moves may be substantially parallel to the longitudinal axis of each of the receiving portions 6, such that when the force distribution device 8 moves, the plunger moves into or out of the corresponding cylinder.

[0078] In some forms, for example in Figures 3 to 11 In the illustrated form, the drug delivery device 100 further includes a guide portion 10 configured to guide a force distribution device 8 along a predetermined path during use. In some forms, such as Figures 3 to 11 In some forms, the guide portion 10 may be incorporated as part of the mounting component 1, as will be described in more detail later. The guide portion 10 may be configured to engage with the force distribution device 8 to maintain the force distribution device 8 along a predetermined path. The guide portion 10 may extend longitudinally in the direction of movement of the force distribution device 8 during use, for example, parallel to the orientation of the plunger 26 of the syringe containing the accommodating portion 6. As the force distribution device 8 moves along the predetermined path, the guide portion 10 may also maintain the force distribution device 8 at a predetermined angular orientation relative to the plunger of the accommodating portion 6. In some forms, this predetermined orientation may be substantially perpendicular to the path, i.e., substantially perpendicular to the orientation and direction of movement of the plunger. In other forms, the predetermined orientation may be at a non-perpendicular angle to this orientation / direction.

[0079] exist Figures 1 to 11 In the illustrated embodiment, the force distribution device 8 includes one or more convex portions, and the guide portion 10 includes a corresponding number of concave portions. In some embodiments, such as... Figures 3 to 7 As shown, the convex portion can take the form of an elongated member, such as a rod, protruding outward from the planar portion of the force distribution. The elongated member is positioned within a corresponding shaped and positioned hole in the mounting component 1, and can slide into and out of said hole, thereby guiding the movement of the force distribution device 8. Figures 3 to 7 In one example, the force distribution device 8 includes elongated members near each lateral end. Figures 8 to 11In one form, the guide portion 10 includes first and second recesses 10 configured to receive, in use, first and second protrusions 9 of the force distribution device 8, respectively. The first and second recesses 10 are substantially linear and parallel to each other and to the longitudinal axis of the receiving portion 6. The force distribution device 8 is configured to move along a predetermined linear path parallel to the longitudinal axis of the receiving portion such that, when the force distribution device 8 is moved to draw a dose of medication into each of the receiving portions 6, the first and second protrusions 9 remain engaged with the first and second recesses 10. The length of each of the recesses 10 is at least as long as the stroke length of each of the plungers 36 of the receiving portion 6. In other forms (not shown), the force distribution device 8 may include one or more concave portions, and the guide portion 10 may include a corresponding number of convex portions.

[0080] In some forms, for example in Figures 1 to 2 In this form, the force distribution device can be guided by the structure of the plunger 36 and the cylinder 26 of the syringe itself, and a separate guide part can be eliminated.

[0081] Although the drug delivery device 100 includes a force-dispensing device 8 in the form of technology shown in the figure, it may be absent in other forms. In such forms, the user can simply engage the plunger 26 of the syringe in the container 6 by hand and simultaneously push or pull them through the same distance. The drug delivery device 100 can operate adequately in these forms, although they may be more susceptible to human error than the form in which a force-dispensing device 8 is present, which could result in unequal doses of drug being drawn into the container 6.

[0082] 6.1.3. Storage In a technical form where the drug delivery device 100 operates by simultaneously drawing the drug into each of the receiving portions 6, for example... Figure 8 and 9 As shown, the drug delivery device 100 includes a reservoir 5. The reservoir 5 can be any container capable of holding a drug. In some forms, such as the one shown, the reservoir 5 is a syringe comprising a barrel 25 and a plunger 35. The barrel 25 further includes a tip 45 through which the drug can be drawn into and / or dispensed from the syringe 5. In alternative forms, the reservoir can take the form of a vial, bottle, jar, basin, etc.

[0083] To prepare "n" doses by transferring the drug from reservoir 5 to container 6, reservoir 5 can be configured to hold a volume of drug at least equal to the volume of "n" doses. Furthermore, after the drug is transferred from reservoir 5 to container 6, some amount of drug may remain in the fluid connection between reservoir 5 and container 6. Therefore, in the forms shown, reservoir 5 can be configured to hold at least a certain volume of drug, said certain volume being equal to the required dose plus the total volume of the fluid connection, such as catheter 7.

[0084] 6.1.4. Fluid Connections In an exemplary form of this technology, for example, Figure 8 and 9 As shown, the drug delivery device 100 may include a fluid connection configured to fluidly connect the receptacle 6 to the reservoir 5. In some forms, the receptacle 6 may be fluidly connected to the reservoir 5 in parallel; for example, each of the receptacles 6 may be directly fluidly connected to the reservoir 5.

[0085] Any suitable fluid connection can be provided between the reservoir 5 and the receiving portion 6. In some forms, such as... Figure 8 and 9 As shown, the fluid connection may include a conduit 7. The conduit 7 may comprise multiple individual components in the assembly. For example, in the shown form, the conduit 7 may include a reservoir connector 27, the first end of which is configured for fluid connection to the tip 45 of the cylinder 25 of the reservoir 5. The conduit 7 may further include three tubes 37, the respective first ends of which are configured for fluid connection to a receiving connector. Each of the receiving connectors is configured for fluid connection to a respective tip 46 of the cylinder of the receiving portion. Furthermore, the second end of the reservoir connector 27 is configured to connect to each second end of the tubes 37, as shown... Figure 8 and 9 As shown. In this way, the reservoir 5 is fluidly connected to the receiving portion 6, wherein the receiving portions are connected in parallel.

[0086] As previously described, in the illustrated form, the container 6 and reservoir 5 are syringes. Therefore, when the plunger 36 of the container is withdrawn, a negative pressure (or suction force) is generated in the cylinder 26 of the container 6, and the medication is drawn from the reservoir 5 into the cylinder 26 via the fluid connection. This also generates a negative pressure (or suction force) in the cylinder 25 of the reservoir 5, causing the plunger 25 of the reservoir 5 to be drawn further downwards into the cylinder, where the base of the plunger 25 contacts the medication. This allows the user to read patient-related parameters corresponding to the volume level of the medication in the reservoir 5, for example, by identifying graduations flush with the base of the plunger 25 (explained in more detail below).

[0087] The first end and tip 45 of the reservoir connector 27 can be removably attached to each other. Similarly, each first end of the receiving connector can be removably attached to the corresponding tip 46.

[0088] This allows the reservoir 5, the housing 6, and the conduit 7 to be assembled together and disassembled.

[0089] In some forms, the connections between the components of the catheter 7, the reservoir 5 and the catheter 7, and the receiving portion 6 and the catheter 7 can be fluid-tight to improve the accuracy of the dosage prepared using the drug delivery device 100 and eliminate drug waste.

[0090] In the illustrated configuration, the cross-sectional area, length, and / or flow rate (i.e., the rate at which the drug flows through the tube) of each of the three tubes 37 can be substantially equal, such that during use of the drug delivery device 100, substantially equal volumes of drug are transferred from the reservoir 5 to each of the receptacles 6 at a uniform rate. In an alternative configuration, the cross-sectional area, length, and / or flow rate of the receptacle portion 37 can vary depending on the desired volume for each dose and / or the rate at which each dose of drug is prepared. The dimensions of the receptacle connector 37 can be configured to correspond to the dimensions of the respective receptacles 6 to which the tubes of the receptacle connector 37 are respectively attached, to achieve the desired dose volume and dose preparation rate for each dose.

[0091] 6.1.5. Indicators In exemplary forms of this technology, such as those shown in the figures, the drug delivery device 100 includes an indicator 15 with a set of graduated markings. The markings can take any suitable form to indicate the receiving portion (which may be one of the receiving portions 6, or in…). Figures 8 to 11 The scale markings represent how the amount of drug in reservoir 5 corresponds to a parameter indicated by graduations. For example, the graduations could be a set of parallel lines, dots, or other markings. Alternatively, the graduations could be markings in the form of physical shapes, such as notches, holes, or protrusions. The graduations may further include a set of parameter values ​​arranged such that a parameter corresponding to the amount of drug in reservoir 5 can be determined. For example, values ​​could be provided for each graduation, or for the graduations at regular intervals (e.g., every five or ten graduations).

[0092] In some forms, the drug delivery device 100 may include an indicator member 16 configured to occupy multiple positions relative to an indicator to facilitate reading the indicated value of a parameter. In some forms, for example, Figures 1 to 7As shown, the indicator member 16 can extend outward from the force distribution device 8 toward the indicator to indicate parameters. For example, the indicator member 16 may have a first portion mounted to the force distribution device and a second portion positioned near the indicator. The indicator member may include a rod or other elongated member, and in some forms, the first end of the rod or elongated member may be mounted to the force distribution device, and the second end of the rod or elongated member may be positioned near the indicator. In other forms, such as... Figure 8 and 9 As shown, the position of the plunger 35 relative to the cylinder 25 can indicate parameters. The indicator component may include indicator marks, such as arrows or lines, to aid in reading the indicator. Depending on the specific circumstances, the value of the parameter may be indicated by a mark pointing to the end of the indicator mark or indicator component, or a mark flush with the end of the indicator mark or indicator component.

[0093] In some forms, for example in Figures 1 to 7 In this form, the markings can be a set of parallel lines marked on the mounting component 1 of the drug delivery device 100. The markings can be positioned in a place easily visible to the user, such as on the outward-facing surface of the mounting component 1.

[0094] In the case where reservoir 5 is in the form of a syringe, for example... Figure 8 and 9 As shown, the markings may be a set of parallel lines circumferentially oriented around the cylinder 25 and along its length. The plunger 35 may be configured to be positioned relative to the scale markings of the indicator 15 to allow the user to read a parameter value corresponding to the volume level of the drug in the reservoir 5. In some forms, the base of the plunger 35 (which is configured to contact the drug in use) may be configured to indicate a parameter value corresponding to the volume level of the drug in the reservoir 5. The cylinder 25 of the reservoir 5 may be substantially transparent or translucent to allow the user to read the parameter value relative to the plunger 35. In other forms, the scale markings may alternatively or additionally be provided on the indicator member 16, for example, on a rod / elongated member mounted to the force distribution device 8 or on the plunger 35 of the syringe. In the latter example, a marking on the plunger aligned with an indicator on the cylinder 25 or a portion of the cylinder (such as its end) may indicate the relevant value of the parameter.

[0095] In some forms of this technology, the scale markings of indicator 15 indicate patient-related parameters. Examples of suitable patient-related parameters are provided below. The scale markings are calibrated to correspond to a volume of medication suitable for the patient based on the patient-related parameters. For example, the appropriate volume of medication could be the amount indicated by a marking that matches the value of the patient's patient-related parameters.

[0096] Patient-related parameters can be any characteristic of a patient suitable for indicating the dosage of a drug to be administered. Exemplary patient-related parameters include, but are not limited to: weight, body area, age, gestational age (e.g., in the case of preterm infants), height, body mass index (BMI), renal function, etc. An appropriate drug dosage can be determined based on a quantitative measurement of such patient-related parameters. For example, in the case of administering epinephrine to a pediatric patient, the appropriate dosage is determined based on the patient's weight. When this parameter is used to label indicator 15, this avoids the need for the user to calculate the appropriate drug dosage for each patient. Instead, the user can determine the appropriate dosage by identifying a label that matches the patient's patient-related parameters, as will be explained in more detail later.

[0097] In the case of a technology where excess drug is discharged from the container 6 to leave the desired dose, such as Figures 1 to 7 As shown, the spacing of the scale marks on the indicator 15 is related to the volume of medication discharged in each container 6 as the indicator moves from one mark to the next. That is, if each scale mark indicates a unit value of a patient-related parameter, then the volume of medication in each container 6 between each pair of consecutive scale marks of the indicator 15 is the unit volume of medication required for each unit value of the patient-related parameter.

[0098] In these forms of the technology, for example in Figures 1 to 7 In the case of a syringe, the indicator 15 can be positioned in an easily visible location on the drug delivery device 100, such as on and / or beside the container 6. The values ​​of the scale markings can increase in the same direction corresponding to a larger volume of drug in the container 6. In the case where the container 6 is a syringe, as... Figures 1 to 7 As shown, these values ​​can decrease in the direction of the plunger 35's movement during use to dispense medication from the receiving section 6. For example, if the patient-related parameter is weight, a scale mark indicating the maximum weight (which could be 70 kg) can be positioned substantially near the barrel flange 55, and a scale mark indicating 0 kg can be positioned substantially near the tip 45. In other forms, these values ​​can increase or decrease in either direction and can start from a value other than zero in the relevant units.

[0099] In the case of a technique that draws the drug from the reservoir 5 into the receiving section 6, such as Figures 8 to 11 As shown, if each scale mark indicates a unit value of a patient-related parameter, then the volume of drug in reservoir 5 between each pair of consecutive scale marks of indicator 15 is the unit volume of drug required to prepare "n" doses for each unit value of the patient-related parameter. Therefore, in these forms, the distance between consecutive scale marks and the corresponding volume of drug in reservoir 5 between consecutive scale marks depend on the following factors: - The quantity of the dose to be prepared; and - The volume of the drug per unit value that is appropriate for the patient's relevant parameters.

[0100] In some exemplary forms of this technology, such as the form shown, the patient-related parameter is the patient's weight. In these forms, the indicator 15 has a scale marking in units of patient weight, such as kg (although other units of weight (or mass) may be used in other forms). Figure 10 An exemplary indicator 15 is shown, which illustrates the use of Figure 8 and 9 The reservoir 5 in the drug delivery device 100. These indicators 15 are configured such that the smallest increment in the markings corresponds to 1 kg of patient weight. In other words, each successive scale mark indicates an increase of 1 kg. For example, the bottom scale mark of indicator 15 reads 0 kg. The next scale mark indicates 1 kg (although the number is not indicated on indicator 15).

[0101] exist Figures 8 to 11 In the illustrated technical form, three doses are to be prepared (i.e., there are three nacelles 6 fluidly connected to reservoir 5). Therefore, the graduations are calibrated such that the volume of drug in reservoir 5 between consecutive graduations is the volume of drug required to be transferred to each of the three nacelles 6 for preparing three doses when the patient's weight is 1 kg. Similarly, the volume of drug between the 0 kg and 10 kg graduations is the volume of drug required to be transferred from reservoir 5 to the nacelles 6 for preparing three doses for a patient weighing 10 kg.

[0102] The indicator can range from zero to the upper limit; for example, indicator 15 can range from 0 kg to 70 kg. This means that reservoir 5 is suitable for preparing doses of medicine for individuals weighing between 0 kg and 70 kg. This weight range can be selected so that the drug delivery device 100 can be used for pediatric purposes (patients weighing up to 70 kg can be considered pediatric patients). In alternative forms, indicator 15 can have different ranges and / or different scales, as appropriate for the intended use and the medicine to be administered.

[0103] In instances where weight is a patient-related parameter, the following formula can be used to calibrate the scale markings of indicator 15, ranging from 0 kg to 70 kg:

[0104] in z = the length of each increment unit on the scale (in millimeters). and d = Total displacement of plunger 35 during filling (in millimeters).

[0105] The graduation mark indicating that the reservoir 5 contains a sufficient volume of medicine to prepare three doses at the maximum body weight (e.g., 70 kg) is located substantially near the tip 45. The graduation mark indicating 0 kg is located on the opposite end of the cylinder 25, substantially near the cylinder flange 65 of the reservoir 5. In other words, in Figures 8 to 10 In the illustrated form, the values ​​of patient-related parameters increase in the direction opposite to the volume of medication in reservoir 5. Since reservoir 5 is a syringe in the illustrated form, the value of the parameter (in this case, body weight) increases in the same direction as the direction in which the plunger 35 moves during use to dispense medication from reservoir 5 through tip 45.

[0106] In alternative forms (not shown in any figure), the values ​​of patient-related parameters (e.g., weight) in the graduations can increase in the same direction corresponding to an increase in the volume of medication in reservoir 5. In the case of reservoir 5 in the form of a syringe, these values ​​can decrease in the direction in which the plunger 35 moves during use to dispense medication from reservoir 5. For example, a graduation for maximum weight (which could be 70 kg) can be positioned substantially near the barrel flange 65, and a graduation indicating 0 kg can be positioned substantially near the tip 45. In other forms, these values ​​can increase or decrease in either direction and can start from a value other than zero in the relevant unit.

[0107] In any of the described forms, if the patient's weight is, for example, 20 kg, the plunger 35 of reservoir 5 can be moved through a distance corresponding to 20 kg on the indicator, for example, through 20 graduations on indicator 15. In the illustrated form, the value of 20 kg is added to the value of the graduations indicating the volume level of the medication in reservoir 5 to achieve the final position of plunger 35 relative to said value. In an alternative form, the value of 20 kg can be subtracted from the value of the graduations indicating the volume level of the medication in reservoir 5 to achieve the final position of plunger 35 relative to said value.

[0108] Figure 10The advantage of the orientation of the scale markings shown is that the reservoir 5 can initially be filled to the 0 kg mark. The medication can then be transferred from the reservoir 5 to the container 6 until the plunger 35 reaches a scale marking corresponding to patient-related parameters matched to the patient's characteristics, for example, until the plunger reaches a mark corresponding to the patient's weight. For example, if three doses of medication are to be prepared for a patient weighing 20 kg, the medication can be drawn into the container 6, where the volume level of the reservoir 5 starts from the 0 kg mark and continues until the volume level reading of the reservoir 5 is 20 kg. This arrangement is advantageous because it eliminates the need for user calculations, thereby reducing the possibility of errors.

[0109] In similar Figures 8 to 11 In some forms, the drug delivery device 100 can be configured such that when the reservoir 5 is full and no drug has been dispensed from the reservoir 5, the base of the plunger 35 can be located at 0 kg on the indicator, meaning that there is no drug in the fluid connection (e.g., catheter 7) between the reservoir 5 and the receiving portion 6. However, once drug begins to be dispensed from the reservoir 5, the drug will first fill the volume in the fluid connection before being dispensed into the receiving portion 6. In some forms, the reservoir 5 can be initially filled such that the plunger 35 moves beyond a scale mark corresponding to zero dose (e.g., beyond the 0 kg mark), such that the plunger 35 reaches the zero dose mark at the point where the drug is first dispensed into the receiving portion 6. To facilitate this, the indicator 15 can include one or more marks (e.g., beyond the 0 kg mark) on the other side of the mark corresponding to zero dose to account for the volume of drug that needs to pass through the fluid connection. Therefore, when measuring the “…” in the above formula… d When the value is "", some margin can be allowed to account for such tags.

[0110] This technology is similar to Figures 8 to 11 In some forms of this formulation, the volume of the drug in reservoir 5, used to prepare “n” doses of drug for patients weighing between 0 kg and 70 kg, can be calculated using the following formula A:

[0111] in V = Volume in the storage container x = Manufacturer's recommended dosage n = Number of doses to be prepared t = The volume of remaining medication in the catheter.

[0112] To provide an example of implementing this calculation, in one form, the value of "x" can be 0.1 mL / kg adrenaline, the value of n can be 3 (i.e., there are three nacelles 6), and the value of t can be approximately 0.4 ml (depending on the volume within the fluid connection, such as the various sections of the conduit 7). Based on this, in this example, the minimum required volume of reservoir 5 is 21.4 ml.

[0113] The following is a more general formula for calculating the volume of drug in reservoir 5 for preparing “n” doses of drug based on patient characteristics (such as weight, gestational age, body surface area, etc.):

[0114] in V = Volume in the storage container The patient's unique characteristics (i.e., weight, gestational age, body surface area, etc.) n = The number of doses to be prepared t = Volume of the fluid connector.

[0115] Commercially available syringes with a volumetric capacity equal to (or alternatively greater than) the required volume of drug (21.4 ml) can be used as syringes. Figures 8 to 11 The reservoir 5 in the drug delivery device 100. The indicator 15 may be prepared with graduations calibrated in the manner described above. The indicator may be located on a label attached to the syringe 5, or otherwise applied to the syringe 5, such as by direct marking or etching onto the syringe. In some forms, any existing volume markings on the syringe may be erased, while in others, graduations of the indicator 15 may be provided in addition to any existing markings on the syringe. In alternative forms, the indicator may be located on a portion of the drug delivery device adjacent to the reservoir 5, for example, a mark may be located next to the barrel 25 of the syringe 5.

[0116] 6.1.6. Stopping components In some forms, the drug delivery device 100 may include a stop 50 to prevent the mechanism for simultaneously adjusting the amount of drug in the container 6 from moving beyond its limit. In some forms, the stop 50 may be configured to prevent the force distribution device 8 from moving beyond its limit. This reduces the risk that the user will adjust the amount of drug in the container 6 to an undesirable amount, for example, unintentionally discharging too much or too little drug from the container 6, or unintentionally inhaling too much or too little drug into the container 6.

[0117] The stop 50 may be a component or assembly or a part positioned against the drug delivery device 100 that moves when the adjustment mechanism is actuated, such as a component positioned against the force distribution device 8 or a component directly or indirectly mounted to the force distribution device.

[0118] Furthermore, this technology may include a stop adjustment mechanism to allow a user to adjust the position of the stop 50. The stop 50 can be adjusted according to the desired dose of the drug to be produced in the receiving portion 6. In some forms, the stop adjustment mechanism may allow the stop 50 to be adjusted to multiple discrete positions. In other forms, the stop adjustment mechanism may allow the stop 50 to be adjusted to a continuous range of positions.

[0119] Figure 1 and 2 An exemplary form of the stop 50 and the stop adjustment mechanism is shown. In this form, the stop 50 includes an elongated protrusion, and the drug delivery device 100 includes a body, such as a mounting member 1, which includes a plurality of slots 52 into which the stop 50 can be inserted (therefore, this stop adjustment mechanism is of the type that allows discrete adjustment of the stop 50). In this form of the art, the drug delivery device 100 includes an indicator member 16 extending outward from the force distribution device 8, as previously described. The stop 50, the slots 52, and the indicator member 16 are configured such that when the stop 50 is inserted into the slot 52, the end of the stop 50 protrudes outward from the corresponding slot 52, and the end of the stop 50 is positioned in the path of the indicator member 16 such that when the force distribution device 8 is sufficiently pushed inward, the indicator member 16 abuts against the end of the stop 50 and prevents further movement of the force distribution device 8, thereby preventing further discharge of the drug from the receiving portion 6. In some forms, as shown, the stop 50 may have a flanged end to limit the distance it can be inserted into the slot 52, thereby ensuring a sufficient amount of outward protrusion. In other forms, sufficient protrusion of the stop 50 may be achieved by the slot being shorter than the stop.

[0120] In the illustrated configuration, multiple slots can be positioned corresponding to the markings on indicator 15. Therefore, the user can select the desired dose by inserting stop 50 into the slot indicating the dose. Figure 2 An example of such a position of the stop 50 is shown. This causes the indicator member 16 to abut against the stop 50 at a position corresponding to the volume of undischarged drug in each of the accommodating portions 6, the volume of undischarged drug matching the dose indicated by a marking in the slot in which the stop is positioned.

[0121] In other forms, different stop adjustment mechanisms may be used. For example, in some forms, the drug delivery device 100 may include a dial that can be rotated by a user. The dial can be rotated to indicate different values ​​of patient-related parameters corresponding to different doses, as previously described. For example, in one form, as the dial is rotated, an arrow on the dial may point to different marks on a scale around the dial. In another form, the dial may have a hole formed therein, the hole being positioned to reveal different values ​​of patient-related parameters marked on a surface behind the dial when the dial is rotated. The dial may be connected to a stop 50, which is configured to move back and forth, for example, via one or more gears, according to the rotation of the dial. This stop adjustment mechanism may be of the type that allows discrete or continuous adjustment of the stop 50, depending on whether the dial is allowed a continuous range of positions or a discrete number of positions.

[0122] In another form, the stop 50 may be connected to a slider, which the user can move between different positions to select desired patient-related parameters and thus the corresponding position of the stop 50. This stop adjustment mechanism may be of the type that allows continuous adjustment of the stop 50. In some forms, the slider may be mounted on a ratchet mechanism that can restrict the position of the slider to multiple discrete positions.

[0123] 6.1.7. Installation Components The drug delivery device 100 may further include a mounting component 1, other components of the drug delivery device 100, such as a receiving portion 6, and, if present (e.g., in...). Figures 8 to 11 In the case of a device in the form of a reservoir 5 and fluid connections (e.g., tubing 7), the device can be installed to the mounting component during use. The mounting component 1 can provide a platform on which all components of the drug delivery device 100 are assembled. This improves the ease and convenience of assembling the drug delivery device. Furthermore, the mounting component 1 provides the advantage of holding the installed components in a fixed position relative to each other during use. This improves the ease and convenience of manipulating the assembled drug delivery device 100 during use.

[0124] In some forms, one or more of these components can be directly mounted to mounting component 1, and in other forms, one or more of these components can be indirectly mounted to mounting component 1. For example, in Figure 8 and 9 In the case of the conduit 7 in the form shown, it is indirectly installed to the mounting component 1 by connecting to the reservoir 5 and the receiving part 6, and those components are directly installed to the mounting component 1.

[0125] In some forms, for example Figure 1 and 2As shown, the mounting component 1 may include an elongated body, and the receiving portion 6 may be mounted around the elongated body. For example, the elongated body may include a recess arranged around the outer surface of the elongated body, for example in... Figure 1 and 2 In the case of each corner, or in other forms on each surface. The recess may have a suitable size and shape for accommodating the receiving portion 6 or a portion thereof.

[0126] In other forms, for example Figures 3 to 7 As shown, mounting component 1 may include a frame 60 to which receiving portion 6 can be mounted. Frame 60 may include structures or recesses of suitable size and shape for receiving receiving portion 6 or a portion thereof. Frame 60 may include a bracket 62 at one end, configured to support the end of frame 60 in an elevated position relative to the opposite end of the frame when frame 60 is placed on a flat surface. Frame 60 may be configured such that receiving portion 6 is received by the frame, wherein the open end of receiving portion (e.g., tip 46 in the case of a syringe) is close to bracket 62, such that when receiving portion 6 is mounted to mounting component 1, the open end of receiving portion 6 is elevated relative to its opposite end (e.g., distal end of plunger 36 in the case of a syringe). For example, as... Figure 3 As shown, when housed in the frame 60, the receiving portion 6 can be tilted. In this position, the drug can be held within the receiving portion 6 and will not spill out due to gravity.

[0127] In some forms, for example in Figure 8 and 9 In the illustrated form, the mounting component 1 may include a substantially flat surface to which the reservoir 5 and the receiving portion 6 can be mounted. The substantially flat surface provides easy visibility of the indicator 15 and easy access to the reservoir 5, the receiving portion 6, and the force distribution device 8. Furthermore, the substantially flat surface allows for a relatively coplanar arrangement of components to assemble the drug delivery device 100, which improves ease of assembly. In this form, the mounting component 1 may include a plate. The plate may be formed of a material that makes it substantially rigid in order to stably hold the mounted components in place. All mounted components may be mounted to the same side of the plate, i.e., one of its flat surfaces.

[0128] In other forms (not shown in any figures), the mounting component may include multiple surfaces that may be coplanar or non-coplanar with each other. Furthermore, the multiple surfaces of the mounting component may be discontinuous. For example, a first portion of the mounting component may secure the reservoir 5, and a second portion of the mounting component may secure the receiving portion 6. The first and second portions of the mounting component may be separable from each other. In other forms, the first and second portions may be connected to each other but not coplanar.

[0129] In some forms, such as Figure 8 and 9 As shown, the reservoir 5 and the receiving portion 6 are formed of syringes, and the reservoir 5 and the receiving portion 6 can be mounted on the mounting member 1 with the syringe of the receiving portion 6 in an inverted orientation relative to the syringe of the reservoir 5. Furthermore, the reservoir 5 and the receiving portion 6 can be arranged such that the tip 45 of the reservoir 5 is close to the tip 46 of the receiving portion 6. This arrangement allows for a relatively short length and therefore a smaller volume of the fluid connection between the reservoir 5 and the receiving portion 6, such as the conduit 7.

[0130] In some forms, such as Figures 3 to 9 As shown, the containers 6 can be arranged in a row adjacent to each other. For example, in the form where the containers 6 are formed of a syringe, the syringe barrels 26 can be arranged substantially parallel and their ends substantially aligned. The uniform arrangement of the containers 6 facilitates the rapid use of the drug delivery device 100, for example, it can promote the use of a force-distributing device to operate the plunger of the syringe in the containers 6. In some forms, such as... Figures 1 to 9 As shown, the accommodating portions 6 can be arranged substantially parallel to each other, and if a reservoir 6 is present (such as in...), Figure 8 and 9 In the case of a certain form, the orientation of the reservoir 6, for example, the barrels of the corresponding syringe, can be substantially parallel to each other. In other forms, the accommodating portions 6 can be arranged in another way, such as in a bundle. For example, they can be arranged in multiple parallel rows, including the accommodating portions in one row being positioned in a slot between the accommodating portions in adjacent rows, i.e., tightly packed when viewed from the end-on.

[0131] In some forms, such as Figures 1 to 9 As shown, each of the containers 6 and / or reservoirs 5 (if present), as well as one or more components of the catheter 7, can be removably attached to the mounting component 1. This allows the reservoir 5 to be easily and conveniently removed from the mounting component 1 for refilling and / or cleaning, and to be reattached to the mounting component 1 for reassembly of the drug delivery device 100. Similarly, the removably attached containers 6 allow each of the containers 6 to be easily and conveniently removed from the mounting component after the container 6 has contained the desired dose for administration to the relevant patient. After the dose is administered and / or after cleaning the container 6, the container can be reattached to the mounting component 1.

[0132] In some forms, such as Figure 8 and 9As shown, mounting component 1 may include engagement assemblies 11 and 21 to secure reservoir 5 to mounting component 1. The flange 55 of the cylinder 25 of reservoir 5, or a portion of reservoir 5 near the flange, may be secured to mounting component 1 via engagement assembly 11. The neck region of the tip 45 of reservoir 5, or a portion of reservoir 5 near the neck region, may be secured to mounting component 1 via engagement assembly 21.

[0133] In some forms, such as Figures 1 to 9 As shown, the mounting component 1 may include engagement components 31 and / or 41 to secure the receiving portion 6 to the mounting component 1. A corresponding neck region of each of the tips 46, or a portion of the receiving portion 6 adjacent to the corresponding neck region, may be secured to the mounting component 1 by a corresponding engagement component 31. Each of the receiving portions 6 may include a corresponding cylindrical flange 55. Each of the cylindrical flanges 55, or a portion of the receiving portion 6 adjacent to the cylindrical flange, may be secured to the mounting component 1 by a corresponding engagement component 41.

[0134] In some forms, the engagement assemblies 11, 21, 31, and 41 may comprise pairs of engagement members, wherein each member of the pair is located on a corresponding side of a sub-component of the reservoir 5 or a sub-component of the receiving portion 6, and each member engages with the corresponding sub-component in use to secure the corresponding sub-component to the mounting member 1. In some forms, the engagement assemblies may secure the corresponding sub-component to the mounting member 1 by friction engagement. For example, as... Figures 1 to 9 As shown, the corresponding engaging members of the engaging assemblies can be arranged at appropriate distances from each other, allowing the corresponding sub-components to be securely engaged between the engaging members. Some engaging members, such as those forming engaging assemblies 11 and 41 (which can engage the flange of the syringe in use), can include one or more slits within which the flange of the corresponding syringe can be positioned to hold the sub-component in place. In an alternative form, one or more of the engaging assemblies can be configured to receive a corresponding sub-component of the reservoir 5 or a sub-component of the receiving portion 6 in a snap-fit ​​connection. The engaging members of the engaging assemblies can include one or more protrusions extending outward from the surface of the mounting member 1. The protrusions can be attached to the mounting member 1, for example, by adhesive or fasteners, or the protrusions can be integrally formed with the mounting member 1, for example, as part of a molded component identical to the mounting member 1.

[0135] In some forms, such as Figures 3 to 6 As shown in Figures 8 and 9, one of the joining members of a joining assembly can be formed together with the joining member of another joining assembly. A similar arrangement can also be applied to another pair of joining members.

[0136] In some forms, the drug delivery device 1 may include a housing 70 for housing at least some of the components of the drug delivery device 1, such as the receiving portion 6. In some instances, the housing 70 may house all the components of the drug delivery device 1. In some forms, some or all portions of the housing 70 may differ from portions of the drug delivery device 1 described so far. In other forms, one or more portions of the drug delivery device 1 described so far may form part of the housing 70. For example, in the case of the shown form, the force distribution device 8 may form part of the housing. Figures 5 to 7 In the form shown, the housing 70 may include the frame 60. Alternatively or additionally, a support 62 may form part of the housing 70; for example, the support 62 may be container-shaped and may surround the tip 46 of the syringe when folded. In some forms, such as in… Figures 3 to 9 In this case, the mounting component 1 can be included as part of the housing 70. For example, as... Figure 6 and 7 As shown, in some forms, the drug delivery device 100 can be arranged in a receiving configuration, wherein the housing 70 can completely accommodate the receiving portion.

[0137] In similar Figure 8 and 9 In some of the forms shown, the mounting member 1 may include an edge surrounding the outer edge of a surface. The edge may be sufficiently upright from the flat surface of the mounting member 1 such that it extends above some or all of the height of the component mounted to the mounting member 1. The edge may facilitate positioning a cap (not shown) above the component of the drug delivery device 100 mounted to the mounting member 1, for example, the cap may extend across the top of the edge. In this way, the component of the drug delivery device 100 can be housed within a housing consisting of the mounting member 1 and the cap. This allows the drug delivery device 100, which has been prepared for use (i.e., where the drug is contained in the reservoir 5), to be supplied to, for example, clinics, hospitals, etc. The contents of the drug delivery device 100 can be sterilized, and the housing can be configured to maintain the contents in a sterile state, for example, the housing may be hermetically sealed.

[0138] The housing 70 can be configured to accommodate a pre-prepared receptacle 6 (in the case of operation by discharging excess drug into the receptacle 6) or a reservoir 5 (in the case of operation by drawing a desired dose of drug into the receptacle 6), for example, in the case of a syringe, wherein its plunger extends. This can be the configuration of the drug delivery device 100 before the preparation of individual doses of drug, and therefore the configuration in which the drug delivery device 100 is transported and supplied to its place of use.

[0139] 6.1.8. Drug Capture Section In some forms, the drug delivery device 100 may include a drug-capturing portion 80 configured to capture drug discharged from a plurality of receptacles 6 during the preparation of each dose of drug. The presence of the drug-capturing portion 80 may be particularly relevant to the form of the art, such as Figures 1 to 7 The ones shown, wherein the drug delivery device 100 operates by discharging excess drug into the container 6 to prepare a desired dose.

[0140] In some forms, the drug-capturing portion 80 may include a container-shaped portion configured to capture and retain drug that falls into the receiving portion 6 under gravity; for example, the drug-capturing portion 80 may be a cup-shaped recess in another component. In some forms, the drug-capturing portion 80 may include a portion of the housing 70. Figure 1 and 2 In the case of a housing (not shown), the casing may include a drug-capturing portion 80 in the form of a tray, within which an assembly consisting of a receiving portion 6 and a mounting component 1 (i.e., the component shown) can be placed. Any drug discharged from the tip of the receiving portion 6 can be captured in the tray. In another example, for example as... Figures 3 to 7 As shown, the housing 70 may include a portion surrounding the tip 46 of the receiving portion 6 when the drug delivery device 100 is in the receiving configuration, and this portion may unfold to form a container-shaped portion (e.g., cup-shaped or trough-shaped) located below the tip when the tip 46 of the receiving portion 6 is mounted in the mounting member 1.

[0141] In addition, in some forms (such as in Figures 3 to 7 In the case shown, the drug capture portion 80 can also be used as a stent 62 as described above.

[0142] exist Figures 3 to 7 In this form, the drug capture section 80 can be configured to deploy (e.g., Figure 6 (as shown), so as to facilitate the movement of the drug capturing portion between a configuration in which the drug capturing portion 80 is positioned below the tip of the receiving portion 6 and serves as a support and a configuration in which the drug capturing portion receives the tip of the receiving portion 6.

[0143] In some forms of this technology, the drug-capturing portion 80 may include a fluid absorber. The fluid absorber may be positioned relative to other components of the drug delivery device 100, for example, within the housing 70, such that the drug discharged from the containment portion 6 can contact the fluid absorber. For example, the fluid absorber may be positioned within the aforementioned container-shaped portion or tray, for instance, at the bottom of the aforementioned container-shaped portion or tray. The fluid absorber may be formed from any suitable fluid-absorbing material, such as fabric, sponge, sodium polyacrylate, terry cloth (towel), etc.

[0144] 6.1.9. Time display device In some forms, the drug delivery device 100 may further include a time display device. The time display device may be positioned in a visible location on the drug delivery device 100, for example, mounted to mounting component 1, so that the user of the drug delivery device 100 can monitor the passage of time. This can help the user track when the next dose will be administered. Figures 3 to 9 In this configuration, the time display device can be mounted on the same side of the mounting component 1 as the other components of the drug delivery device, and positioned to provide good visibility for the user.

[0145] 6.1.10. Tags In some forms, the drug delivery device 100 may include one or more labels configured to facilitate the use of the device. For example, in some forms, the drug delivery device 100 may further include one or more dose labels that number each of an “n” number of doses. The dose labels may use the number “1” to mark one receiving portion 6, the number “2” to mark an adjacent receiving portion 6, and the number “3” to mark the next receiving portion 6. Between labels “1” and “2” and between “2” and “3”, the dose labels may indicate a recommended time interval between subsequent dose administrations. This indicated time interval of the dose labels, together with a time display device, can facilitate the user's ability to track the time between doses and prompt them to administer subsequent doses.

[0146] The dosage label can be located on the drug delivery device 100 below the receiving portion 6, for example, on the mounting component 1. Alternatively, the dosage label can be located anywhere on the mounting component 1 or on another part of the drug delivery device 100, wherein the information on the dosage label is visible to the user and information relating to each receiving portion 6 is conveyed to the user. The dosage label can be a continuous label, or it can contain multiple sub-labels.

[0147] The drug delivery device 100 may further include a drug label that provides drug-related information, such as the name and / or type of the drug, the concentration of the drug, the prescribed dose ratio relative to patient-related parameters, and / or the method of drug administration. The drug label may be located anywhere on the mounting component 1 or on another part of the drug delivery device 100, for example, at an unobstructed viewpoint providing the information provided by the drug label. In some forms, the drug label may be located on the mounting component 1, on the side of the reservoir 5.

[0148] The drug delivery device 100 may further include a patient-related parameter label that can provide information related to the patient-related parameters to which the scale markings of the indicator 15 are calibrated, and / or instruct the user to consult the indicator 15 to read the value of the patient-related parameter when inhaling the medication into the reservoir 6. The patient-related parameter label may be located anywhere on the mounting component 1 or on another part of the drug delivery device 100, for example, at an unobstructed viewpoint providing the information provided by the patient-related parameter label. For example, the patient-related parameter label may be located on the mounting component 1, on the side of the reservoir 5 (which may be the side of the reservoir 5 opposite the medication label 2).

[0149] 6.2. Drugs According to this technology, certain forms of drug delivery devices 100 can be used with a variety of drugs. Examples of drugs that can be used in drug delivery devices 100 are, but are not limited to: - Sympathomimetic drugs (during resuscitation), such as, but not limited to, adrenaline and noradrenaline; - Antiarrhythmic drugs (used to treat heart disease), such as, but not limited to, amiodarone and lidocaine; - Fibrinolytic agents (used to treat stroke), such as, but not limited to, alteplase. - Anticoagulants (used to treat blood clots), such as, but not limited to, heparin; - Cytotoxic / chemotherapy (to treat cancer), such as, but not limited to, cytarabine; - Electrolytes / minerals (used to treat electrolyte imbalances), such as, but not limited to, potassium and calcium; and - IV contrast agents (in CT scans), such as, but not limited to, meglumine diatrizoate.

[0150] By changing any one or more of the following, the drug delivery device 100 can be adapted for use with different drugs: the capacity of the reservoir 5 and / or the container 6, the indicator 15, the number of containers 6 and / or the label.

[0151] While the exemplary drugs indicated above are suitable for human patients, the technology is not limited to drugs for human use. In some forms of the technology, the drugs may be suitable for veterinary use. In such forms, the container 6 may also be suitable for veterinary use.

[0152] 6.3. Assembly Method Exemplary methods for assembling components of a drug delivery device 100 according to certain forms of the present technology will now be described.

[0153] In the case where the drug delivery device 100 operates by simultaneously discharging excess drug from the container 6 such that the desired dose remains in each of the containers 6, for example... Figures 1 to 7 As shown, the container 6 is at least partially filled with medication. The container is then mounted to the mounting member 1, for example, by mounting the neck region of the tip 45 to a pair of engaging members 21 and mounting the cylindrical flange 55 to a pair of engaging members 11. The container 6 can be filled with as much medication as may be needed in most or substantially all drug administration cases. This is because the device is configured to allow for easy dosing by discharging medication from the container 6 to achieve the correct dose, but adding more medication to the container is more difficult.

[0154] The indicator 15 is configured according to the properties of the drug and patient-related parameters. Based on the position of the indicator member 16 and the amount of drug in the accommodating part 6 when the indicator member 16 is in that position, appropriate values ​​of the patient-related parameters are marked on the scale of the indicator 15.

[0155] In the case of a technology in which the drug delivery device 100 operates by simultaneously inhaling a desired dose of drug into each of the containers 6, for example, Figure 8 and 9 As shown, the minimum volume of drug required to be contained in reservoir 5 to prepare "n" doses of the drug can be calculated. In one form, the drug delivery device 100 can be used to prepare three doses of adrenaline for pediatric use based on the patient's weight. The maximum weight of a pediatric patient can be considered as 70 kg. In this case, the maximum volume of the drug is the volume of drug required to prepare three doses of the drug for a patient weighing 70 kg.

[0156] The minimum volume of reservoir 5 to hold the required volume of medication can be calculated using Formula A, as provided above. As explained earlier, in one application of this formula, the minimum required volume of reservoir 5 can be calculated as 21.4 ml. Therefore, a syringe with a volume capacity of at least 21.4 ml can be selected as reservoir 5.

[0157] The indicator 15 of the reservoir 5 can be prepared by marking the minimum and maximum values ​​of the range of patient-related parameters on the body of the cylinder 25 of the reservoir 5. The minimum value can be marked on the body of the cylinder 25, substantially near the base of the plunger 25, while allowing sufficient margin for the volume of medication that may need to pass through the catheter 7 before being dispensed into the container 6. The maximum value can be marked on the body of the cylinder 25, substantially near the tip 45.

[0158] As described above, in the exemplary form shown, the drug delivery device 100 can be used to prepare doses of epinephrine for pediatric use based on the patient's weight. The maximum weight of a pediatric patient can be considered to be 70 kg. The minimum weight can be 0 kg. Therefore, 0 kg can be marked on the body of the cylinder 25 substantially near the base of the plunger 25, while leaving sufficient margin on the other side of the 0 kg mark for marking. Furthermore, 70 kg can be marked on the body of the cylinder 25 substantially near the tip 45. Next, the value of "d", which is the distance between the 0 kg mark and the 70 kg mark, can be measured. The value of "z", the distance between the intermediate scale marks of the patient's weight (in kg) between the 0 kg mark and the 70 kg mark, can be determined using Formula B as described above. Based on the value of "z", scale marks between 0 kg and 70 kg can be marked on the cylinder 15.

[0159] The reservoir 5 may be at least partially filled with the drug and then mounted to the mounting member 1, for example by mounting the neck region of the tip 45 to a pair of engaging members 21 and mounting the cylindrical flange 55 to a pair of engaging members 11.

[0160] A fluid connection can be fluidly connected to the reservoir 5, for example, the reservoir connector 27 of the conduit 7 can be attached to the tip 45.

[0161] A suitable receiving portion 6 can be selected and installed onto the mounting component 1. For example, receiving portions 6 can be selected, each having sufficient capacity to hold a dose of the drug for a 70 kg patient (the maximum weight of the patient suitable for the drug in this example). The corresponding neck region of each tip 46 can be secured to a corresponding pair of engaging members 31, and each cylindrical flange 55 can be secured to a corresponding pair of engaging members 41 to install the receiving portion 6 onto the mounting component 1.

[0162] Fluid connectors can be fluidly connected to the receiving portion 6, for example, each tube of the receiving portion connector 37 can be connected to the tip 46 of each receiving portion 6 respectively.

[0163] The exemplary assembly method may further include the step of engaging the force distribution device 8 to the plunger 36. Each of the engagement portions 28 of the force distribution device 8 may be engaged to each of the plungers 36, respectively.

[0164] The exemplary assembly method may further include the step of mounting a time display device to mounting component 1. Additionally, one or more labels (as in the examples described above) may be attached to the drug delivery device 100.

[0165] As the final step in the assembly process, the component can be placed inside the housing 70.

[0166] 6.4. Dosage Preparation Method The steps of an exemplary method 200 for preparing a medicament for administration to a patient will now be described. In the exemplary method, doses of the medicament (e.g., adrenaline) are prepared using a drug delivery device 100, wherein the dose volume of each dose is determined by the patient's weight.

[0167] First, the patient's weight can be measured. For example, the patient's weight can be determined to be 26 kg.

[0168] Next, the plunger of the container 6 can be moved simultaneously to adjust the amount of medication in the container 6. In some forms, the plunger 36 is simultaneously pushed into its corresponding cylinder 55 to expel the medication from the container 6. In other forms, the plunger 36 can be simultaneously pulled out of its corresponding cylinder 55 to draw the medication from the reservoir 5 and into the container 6. For example, the force distribution device 8 can be moved to push or pull the plunger out of its corresponding cylinder in a uniform manner. In some forms, the clinician can apply force to the first portion 18 of the force distribution device 8 to pull the plunger 36 substantially toward or away from the corresponding tip 46. In the form of expelling medication from the container 6, the medication is pushed out of the tip of the container 6 and, in some forms, can be captured by the drug-capturing portion. In the form of drawing medication into the container 6, the plunger 36 is pulled out of the corresponding cylinder 55, creating a negative pressure or suction force in the cylinder 55. This causes the medication in the reservoir 5 to begin flowing into the cylinder 55 through the conduit 7. When the drug is drawn from the reservoir 7, a negative pressure or suction force is generated in the cylinder 25. The plunger 35 is substantially drawn toward the tip 45 in response to the negative pressure in the cylinders 55A, 55B, and 55C. The displacement of the plunger 35 along the length of the body of the cylinder 25 depends on the volume of drug drawn from the cylinder 25 of the reservoir 5.

[0169] While continuing to apply force to the force distribution device 8, the clinician monitors the indicator 15; for example, the clinician can monitor the movement of the indicator 15 relative to the indicator member 16. Figure 8 and 9 In one example, this could be the base of the plunger 35, which continues to move toward the tip 45 as the drug in the cartridge 25 flows into the container 6. The value of the scale mark against which the indicator member 16 abuts at any given point is the weight of the patient preparing each dose. For example, if the indicator member 16 is positioned against a scale mark with a value of 8 kg, then each container 6 is loaded with a dose suitable for administration to a patient weighing 8 kg.

[0170] In the exemplary method, as long as the base of the plunger 35 has not reached the 26 kg mark (which in this example corresponds to the patient's weight, or more generally, at most a relevant patient-related parameter), the clinician can continue to apply force to the force distribution device 8 to expel or withdraw the drug from the container 6 or to draw the drug into the container.

[0171] Then, when the indicator component 16 reaches the relevant scale mark, such as the 26 kg mark, the clinician can stop applying force to the force distribution device 8. This terminates the adjustment of the medication in the container 6. At this point, each of the containers 6 will contain a dose of medication suitable for administration to a patient with relevant patient parameters, such as a weight of 26 kg.

[0172] Next, the clinician can detach one of the containers 6 from the rest of the drug delivery device. For example, the clinician can first disengage the force distribution device 8 from the plunger 36. Then, the clinician can detach the container 6 from the mounting component 1 for administering a dose of medication to the patient. In some forms, the clinician can take further steps to prepare the container for administering the medication to the patient, for example, by attaching a needle to the tip of a syringe. The dose can then be administered to the patient.

[0173] Furthermore, the preparation method may include steps such as identifying recommended time intervals between consecutive dose administrations and / or monitoring the elapsed time on a time display device to track when the next dose is administered. At this point, another container 6 can be disengaged from the drug delivery device and administer the individual doses of medication to the patient. This cycle can continue as many times as the number of containers, or until the clinician determines that further medication is no longer necessary.

[0174] 6.5. Other Remarks Unless the context explicitly requires otherwise, throughout the specification and claims, the terms “comprise”, “comprising”, etc., shall be interpreted in a inclusive sense, the opposite of exclusive or exhaustive, that is, in the sense of “including but not limited to”.

[0175] The full disclosure of all applications, patents, and publications (if any) cited above and below is incorporated herein by reference.

[0176] Any reference to prior art in this specification is not and should not be construed as an admission or in any way implying that the prior art constitutes part of common general knowledge in the relevant field in any country of the world.

[0177] This technology can also be broadly defined as the parts, elements, and features individually or jointly mentioned or indicated in the specification of this application, in any or all combinations of two or more of said parts, elements, or features.

[0178] The preceding descriptions have referenced wholes or parts having their known equivalents, which are incorporated herein as if described separately.

[0179] It should be noted that various changes and modifications made to the presently preferred embodiments described herein will be apparent to those skilled in the art. Such changes and modifications can be made without departing from the spirit and scope of the present technology and without diminishing its accompanying advantages. Therefore, such changes and modifications are intended to be included within the scope of the present technology.

Claims

1. A drug delivery device for preparing multiple doses of a drug for administration to a patient, the drug delivery device comprising: Multiple accommodating parts; A mechanism for simultaneously adjusting the amount of the drug in each of the plurality of accommodating portions; as well as An indicator comprising a set of scale markings indicating patient-related parameters, wherein the scale markings are calibrated to correspond to a volume of the medication suitable for the patient based on the patient-related parameters.

2. The drug delivery device according to claim 1, wherein the patient-related parameters are weight, gestational age, height, or body surface area.

3. The drug delivery device according to any one of claims 1 to 2, wherein the plurality of receiving portions are arranged in one or more rows adjacent to each other.

4. The drug delivery device according to any one of claims 1 to 3, wherein each of the receiving portions is a syringe, the syringe comprising a barrel and a plunger.

5. The drug delivery device of claim 4, wherein the mechanism includes a force distribution device configured to engage with the plunger of the plurality of syringes to expel the drug from the plurality of syringes or draw the drug into the plurality of syringes by moving the force distribution device.

6. The drug delivery device of claim 5, wherein the force distribution device comprises a plate, wherein a first portion of the plate is configured to be operated by a user during use, and a second portion of the plate is configured to engage with the plunger of the plurality of syringes.

7. The drug delivery device according to any one of claims 5 to 6, wherein the drug delivery device includes an indicator component having a portion mounted to the force distribution device and a second portion positioned near the indicator to indicate the patient-related parameters.

8. The drug delivery device according to any one of claims 5 to 7, wherein the drug delivery device includes a stop for preventing the force distribution device from moving beyond its limit.

9. The drug delivery device of claim 8, wherein the drug delivery device includes a stop adjustment mechanism to allow a user to adjust the position of the stop.

10. The drug delivery device according to any one of claims 1 to 9, wherein the drug delivery device includes a drug capturing portion for capturing drugs discharged from the plurality of receptacles.

11. The drug delivery device of claim 10, wherein the drug delivery device includes a housing accommodating the plurality of accommodating portions, and the drug capturing portion includes a portion of the housing.

12. The drug delivery device according to any one of claims 10 to 11, wherein the drug capturing portion comprises a container-shaped portion of the housing.

13. The drug delivery device according to any one of claims 10 to 12, wherein the drug capturing portion comprises a fluid absorber.

14. The drug delivery device according to any one of claims 1 to 13, wherein the drug delivery device further comprises a reservoir configured to contain the drug, wherein the plurality of receptacles are fluidly connected in parallel to the reservoir to allow a dose of the drug to be transferred from the reservoir to each of the plurality of receptacles, wherein the reservoir includes the indicator.

15. The drug delivery device of claim 14, wherein the reservoir is a syringe, the syringe comprising a barrel and a plunger.

16. The drug delivery device of claim 15, wherein the cartridge includes the indicator, and the position of the plunger relative to the indicator indicates the volume of the drug in the cartridge.

17. A method for assembling a drug delivery system for preparing one or more doses of a drug for administration to a patient, the method comprising the steps of: The reservoir is marked with an indicator, the indicator including a set of scale markings indicating patient-related parameters, wherein the scale markings are calibrated to correspond to a volume of the medication suitable for the patient based on the patient-related parameters; as well as The reservoir is fluidly connected to one or more receptacles to allow a dose of the drug to be transferred from the reservoir to each of the one or more receptacles.

18. A method for preparing one or more doses of a medicament for administration to a patient, the method comprising the steps of: Measure the values ​​of the patient's relevant parameters; Simultaneous adjustment of the amount of the drug in multiple containers begins; Identify target markings on an indicator, the indicator including a set of scale markings indicating the patient-related parameters, the scale markings being calibrated to correspond to a volume of the medication suitable for the patient based on the patient-related parameters; as well as When the indicator indicates the value of the patient-related parameter of the patient, the adjustment of the drug in the plurality of accommodates is terminated.

19. The method of claim 18, wherein the method further comprises monitoring the position of the indicator member relative to the scale mark of the indicator.

20. The method of claim 19, wherein the step of terminating the adjustment of the drug in the plurality of accommodating portions includes terminating the adjustment when the indicator member indicates the target mark.

21. The method according to any one of claims 19 or 20, wherein the step of terminating the adjustment of the drug in the plurality of accommodating portions comprises terminating the adjustment when the indicator member abuts against the stop.

22. The method according to any one of claims 18 to 21, wherein the step of initiating the adjustment of the drug in the plurality of containers includes moving a plunger of each of the plurality of containers relative to the respective cylinder.

23. The method of claim 22, wherein the step of initiating adjustment of the drug in the plurality of receptacles further comprises applying a force to a force dispensing device configured to engage with the plunger of the plurality of receptacles.

24. The method according to any one of claims 22 to 23, wherein the step of initiating the adjustment of the drug in the plurality of containers further comprises pushing the plunger of the plurality of containers into the respective cylinder.

25. The method according to any one of claims 22 to 23, wherein the step of initiating the adjustment of the drug in the plurality of containers further comprises withdrawing the plunger of the plurality of containers from the respective cylinder.

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