Processing method of radix pinelliae praeparata

Abstract

The present application relates to a kind of processing method of law pinellia ternata, specifically, the present application is split into high-temperature soaking, low-temperature soaking, medium-temperature soaking three links by softening soaking.The shallow tissue of pinellia ternata is softened quickly using high-temperature soaking link;Using low-temperature soaking link, starch gelatinization that can be affected by high-temperature soaking link is eliminated, microbial activity is inhibited, pinellia ternata surface layer tissue is shrunk, pinellia ternata internal effective component is limited to be analyzed, and pinellia ternata middle layer tissue is softened;Finally, pinellia ternata inner layer tissue is softened using medium-temperature soaking.Although process step increases, due to the existence of high-temperature soaking and the reason that low-temperature soaking time is shorter, the overall soaking time is still shortened compared with traditional process, and at the same time, the effective component of pinellia ternata can be limited to be analyzed, which helps to improve the quality of final product.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine processing technology, specifically relating to a method for processing Pinellia ternata. Background Technology

[0002] Prepared Pinellia is a processed product of the tuber of Pinellia ternata (Thunb) Breit., a plant in the Araceae family. According to traditional processing methods, Pinellia ternata requires a relatively long soaking time to become prepared Pinellia. However, this prolonged soaking leads to the extraction of effective components from Pinellia ternata, resulting in a less than ideal water-soluble extract content in the final product.

[0003] Furthermore, Pinellia ternata has a dense tuber with a loose outer layer and a compact inner layer. When soaked at room temperature, the outer layer comes into contact with water early and is prone to becoming sour and rotting (spoilage) due to microbial growth, while the inner layer (core) often has not yet absorbed enough water, forming a "white heart". Especially during the hot summer season, the water is extremely prone to deterioration, causing the entire batch of medicinal materials to be wasted.

[0004] Therefore, there is an urgent need for a new processing method for Pinellia ternata to improve the water-soluble extract content of the final product. Summary of the Invention

[0005] The purpose of this invention is to provide a processing method for Pinellia ternata to improve the water-soluble extract content of the finished product. To achieve this objective, the specific technical solution is as follows: A method for processing Pinellia ternata, characterized by comprising the following steps: (1) After cleaning Pinellia ternata, place it in a container and soak it in a soaking solution at 35-45 degrees Celsius for 12-16 hours to soften the superficial tissue of Pinellia ternata. During the soaking process, keep the temperature of the soaking solution constant. (2) After the high-temperature soaking is completed, drain the soaking solution and soak in a 10-15 degree Celsius soaking solution for 6-8 hours to stabilize the tissue structure of Pinellia ternata, shrink the surface tissue of Pinellia ternata, restrict the release of effective components inside Pinellia ternata, and soften the middle tissue of Pinellia ternata. During the soaking process, keep the temperature of the soaking solution constant. (3) After the low-temperature soaking is completed, drain the soaking solution and soak in a medium-temperature soaking solution of 20-25 degrees Celsius to soften the inner tissue of Pinellia ternata until there is no white core inside Pinellia ternata. Keep the temperature of the soaking solution constant during the soaking process. (4) After the medium-temperature soaking is completed, drain the soaking solution and soak it in a mixture of licorice juice and lime water at 20-25 degrees Celsius until the cross-section of Pinellia ternata is uniformly yellow and has a slightly numbing sensation on the tongue. During the process, maintain the concentration and pH value of the mixture and stir. (5) After the detoxification soaking is completed, wash the Pinellia ternata, and then dry and screen it to obtain processed Pinellia ternata.

[0006] Furthermore, the purification process of Pinellia ternata specifically involves: removing impurities, as well as deteriorated, insect-infested, and moldy products, ensuring that the impurities in the purified medicinal material are ≤3%, separating them by size, weighing them, and obtaining purified Pinellia ternata.

[0007] Furthermore, during the soaking process, the liquid level is 8-12 cm higher than the material, and stirring is also performed.

[0008] Furthermore, the specific preparation process of the licorice juice and lime water mixture is as follows: Prepare licorice and quicklime according to the mass ratio of Pinellia ternata: licorice: quicklime = 100: 15: 10; Cut the licorice root into 10-15 mm segments or 2-4 mm slices, place them in an extraction tank, add water and decoct twice. For the first decoction, add 8 times the weight of water, soak for 0.5-1 hour, and decoct for 1.5 hours. For the second decoction, add 7 times the weight of water and decoct for 1 hour. Filter, combine the filtrates, and concentrate them in a cooking pot to 1.5-2.2 times the weight of the net Pinellia ternata. Set aside for use. Take 0.1 times the weight of the cleaned Pinellia ternata and place it in a container. Add water, soak and stir briefly until it is completely dissolved, and set aside for later use. The product is obtained by mixing licorice juice and lime water.

[0009] Furthermore, the drying process specifically involves: spreading the washed medicinal materials evenly on a tray to a thickness of 2-4 cm, and drying them in a gradient of 50-65°C. The initial drying temperature is 50°C, and the temperature is increased by 5°C every 2 hours. Once the temperature reaches 65°C, it is maintained at a constant temperature until the moisture content of the medicinal materials is ≤13%.

[0010] Furthermore, the screening process specifically involves using a 2mm sieve to ensure that the mass of medicinal material debris and impurities after screening is ≤3%.

[0011] The research work of this invention is based on the project "Research on Key Technologies of Processing Pinellia ternata", project number 2025008. Compared with the prior art, the beneficial effects of this invention are: (1) Compared with the traditional process, this application divides the softening soaking into three steps: high-temperature soaking, low-temperature soaking, and medium-temperature soaking. The high-temperature soaking step is used to quickly soften the superficial tissue of Pinellia ternata; the low-temperature soaking step is used to eliminate starch gelatinization that may be caused by the high-temperature soaking step, inhibit microbial activity, shrink the surface tissue of Pinellia ternata, limit the release of effective components inside Pinellia ternata, and soften the middle tissue of Pinellia ternata; finally, the medium-temperature soaking step is used to soften the inner tissue of Pinellia ternata. Although the process steps are increased, due to the presence of high-temperature soaking and the shorter low-temperature soaking time, the overall soaking time is not extended compared with the traditional process, and is even slightly shortened. At the same time, it can limit the release of effective components in Pinellia ternata, which helps to improve the quality of the final product.

[0012] (2) Compared with traditional processes, this application adjusts the drying process to gradient drying. The low temperature and high humidity environment in the early stage prevents the surface from hardening instantly and hinders the leakage of internal moisture. Then, the temperature is gradually increased and the humidity is reduced to accelerate drying. This can effectively avoid the cracking of the surface of the medicinal materials, the brittle texture and loss of effective ingredients caused by traditional high temperature and fast drying. It can also significantly improve the drying efficiency, ensure that the moisture content of the whole batch of medicinal materials is uniform and the color is consistent, and take into account both quality stability and economic benefits. Attached Figure Description

[0013] Figure 1 This is a flowchart illustrating the process of this application. Detailed Implementation

[0014] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application. Example

[0015] A method for processing Pinellia ternata, characterized by comprising the following steps: (1) After cleaning Pinellia ternata, place it in a container and soak it in a 35°C soaking solution for 16 hours to soften the superficial tissue of Pinellia ternata. During the soaking process, keep the temperature of the soaking solution constant. (2) After the high temperature soaking is completed, drain the soaking solution and soak in a 15°C soaking solution for 6 hours to stabilize the tissue structure of Pinellia ternata, shrink the surface tissue of Pinellia ternata, restrict the release of effective components inside Pinellia ternata, soften the middle tissue of Pinellia ternata, and keep the temperature of the soaking solution constant during the soaking process. (3) After the low-temperature soaking is completed, drain the soaking solution and soak in a 20°C soaking solution at a medium temperature to soften the inner tissue of Pinellia ternata until there is no white core inside Pinellia ternata. Keep the temperature of the soaking solution constant during the soaking process. (4) After the medium-temperature soaking is completed, drain the soaking solution and soak it in a mixture of licorice juice and lime water at 20 degrees Celsius until the cross-section of Pinellia ternata is uniformly yellow and has a slightly numbing sensation on the tongue. During the process, maintain the concentration and pH value of the mixture and stir. (5) After the detoxification soaking is completed, wash the Pinellia ternata, and then dry and screen it to obtain processed Pinellia ternata.

[0016] Furthermore, the purification process of Pinellia ternata specifically involves: removing impurities, as well as deteriorated, insect-infested, and moldy products, ensuring that the impurities in the purified medicinal material are ≤3%, separating them by size, weighing them, and obtaining purified Pinellia ternata.

[0017] Furthermore, during the soaking process, the liquid level is 8 centimeters higher than the material, and stirring is also performed.

[0018] Furthermore, the specific preparation process of the licorice juice and lime water mixture is as follows: Prepare licorice and quicklime according to the mass ratio of Pinellia ternata: licorice: quicklime = 100: 15: 10; Cut the licorice root into 15 mm segments or 4 mm slices, place them in an extraction tank, add water and decoct twice. For the first decoction, add 8 times the weight of water, soak for 0.5 hours, and decoct for 1.5 hours. For the second decoction, add 7 times the weight of water and decoct for 1 hour. Filter, combine the filtrates, and concentrate them in a cooking pot to 2.2 times the weight of the net Pinellia ternata. Set aside for use. Take 0.1 times the weight of the cleaned Pinellia ternata and place it in a container. Add water, soak and stir briefly until it is completely dissolved, and set aside for later use. The product is obtained by mixing licorice juice and lime water.

[0019] Furthermore, the drying process specifically involves: spreading the washed medicinal materials evenly on a tray with a thickness of 4 cm, and drying them in a gradient of 50 to 65 degrees Celsius. The initial drying temperature is 50 degrees Celsius, and the temperature is increased by 5 degrees Celsius every 2 hours. Once the temperature reaches 65 degrees Celsius, it is maintained at a constant temperature until the moisture content of the medicinal materials is ≤13%.

[0020] Furthermore, the screening process specifically involves using a 2mm sieve to ensure that the mass of medicinal material debris and impurities after screening is ≤3%. Example

[0021] A method for processing Pinellia ternata, characterized by comprising the following steps: (1) After cleaning Pinellia ternata, place it in a container and soak it in a 45°C soaking solution for 12 hours to soften the superficial tissue of Pinellia ternata. During the soaking process, keep the temperature of the soaking solution constant. (2) After the high-temperature soaking is completed, the soaking solution is drained and the 10-degree Celsius soaking solution is used for low-temperature soaking for 8 hours to stabilize the tissue structure of Pinellia ternata, shrink the surface tissue of Pinellia ternata, restrict the release of effective components inside Pinellia ternata, and soften the middle tissue of Pinellia ternata. The temperature of the soaking solution is kept constant during the soaking process. (3) After the low-temperature soaking is completed, drain the soaking solution and soak in a 25°C soaking solution at a medium temperature to soften the inner tissue of Pinellia ternata until there is no white core inside Pinellia ternata. Keep the temperature of the soaking solution constant during the soaking process. (4) After the medium-temperature soaking is completed, drain the soaking solution and soak it in a mixture of licorice juice and lime water at 25 degrees Celsius until the cross-section of Pinellia ternata is uniformly yellow and has a slightly numbing sensation on the tongue. During the process, maintain the concentration and pH value of the mixture and stir. (5) After the detoxification soaking is completed, wash the Pinellia ternata, and then dry and screen it to obtain processed Pinellia ternata.

[0022] Furthermore, the purification process of Pinellia ternata specifically involves: removing impurities, as well as deteriorated, insect-infested, and moldy products, ensuring that the impurities in the purified medicinal material are ≤3%, separating them by size, weighing them, and obtaining purified Pinellia ternata.

[0023] Furthermore, during the soaking process, the liquid level is 12 cm above the material, and stirring is also performed.

[0024] Furthermore, the specific preparation process of the licorice juice and lime water mixture is as follows: Prepare licorice and quicklime according to the mass ratio of Pinellia ternata: licorice: quicklime = 100: 15: 10; Cut the licorice root into 10 mm segments or 2 mm slices, place them in an extraction tank, add water and decoct twice. For the first decoction, add 8 times the weight of water, soak for 1 hour, and decoct for 1.5 hours. For the second decoction, add 7 times the weight of water and decoct for 1 hour. Filter, combine the filtrates, and concentrate them in a cooking pot to 1.5 times the weight of the net Pinellia ternata. Set aside for use. Take 0.1 times the weight of the cleaned Pinellia ternata and place it in a container. Add water, soak and stir briefly until it is completely dissolved, and set aside for later use. The product is obtained by mixing licorice juice and lime water.

[0025] Furthermore, the drying process specifically involves: spreading the washed medicinal materials evenly on a tray to a thickness of 2 cm, and drying them in a gradient of 50 to 65 degrees Celsius. The initial drying temperature is 50 degrees Celsius, and the temperature is increased by 5 degrees Celsius every 2 hours. Once the temperature reaches 65 degrees Celsius, it is maintained at a constant temperature until the moisture content of the medicinal materials is ≤13%.

[0026] Furthermore, the screening process specifically involves using a 2mm sieve to ensure that the mass of medicinal material debris and impurities after screening is ≤3%. Example

[0027] A method for processing Pinellia ternata, characterized by comprising the following steps: (1) After cleaning Pinellia ternata, place it in a container and soak it in a 40°C soaking solution for 14 hours to soften the superficial tissue of Pinellia ternata. During the soaking process, keep the temperature of the soaking solution constant. (2) After the high-temperature soaking is completed, the soaking solution is drained and the 12-degree Celsius soaking solution is used for low-temperature soaking for 7 hours to stabilize the tissue structure of Pinellia ternata, shrink the surface tissue of Pinellia ternata, restrict the release of effective components inside Pinellia ternata, soften the middle tissue of Pinellia ternata, and keep the temperature of the soaking solution constant during the soaking process. (3) After the low-temperature soaking is completed, drain the soaking solution and soak in a 22°C soaking solution at a medium temperature to soften the inner tissue of Pinellia ternata until there is no white core inside Pinellia ternata. Keep the temperature of the soaking solution constant during the soaking process. (4) After the medium-temperature soaking is completed, drain the soaking solution and soak it in a mixture of licorice juice and lime water at 22 degrees Celsius until the cross-section of Pinellia ternata is uniformly yellow and has a slightly numbing sensation on the tongue. During the process, maintain the concentration and pH value of the mixture and stir. (5) After the detoxification soaking is completed, wash the Pinellia ternata, and then dry and screen it to obtain processed Pinellia ternata.

[0028] In a preferred embodiment, the purification of Pinellia ternata specifically involves: removing impurities, as well as deteriorated, insect-infested, and moldy products, ensuring that the impurities in the purified medicinal material are ≤3%, separating them by size, weighing them, and obtaining purified Pinellia ternata.

[0029] In a preferred embodiment, the liquid level is 10 cm above the material during soaking, and stirring is also performed.

[0030] In a preferred embodiment, the preparation process of the licorice juice and lime water mixture is as follows: Prepare licorice and quicklime according to the mass ratio of Pinellia ternata: licorice: quicklime = 100: 15: 10; Cut the licorice root into 12 mm segments or 3 mm slices, place them in an extraction tank, add water and decoct twice. For the first decoction, add 8 times the weight of water, soak for 0.75 hours, and decoct for 1.5 hours. For the second decoction, add 7 times the weight of water and decoct for 1 hour. Filter, combine the filtrates, and concentrate them in a cooking pot to twice the weight of the net Pinellia ternata. Set aside for use. Take 0.1 times the weight of the cleaned Pinellia ternata and place it in a container. Add water, soak and stir briefly until it is completely dissolved, and set aside for later use. The product is obtained by mixing licorice juice and lime water.

[0031] In a preferred embodiment, the drying process specifically involves: spreading the washed medicinal materials evenly on a tray to a thickness of 3 cm, and drying them in a gradient of 50–65°C. The initial drying temperature is 50°C, and the temperature is increased by 5°C every 2 hours. Once the temperature reaches 65°C, it is maintained at a constant temperature until the moisture content of the medicinal materials is ≤13%.

[0032] In a preferred embodiment, the screening process specifically involves using a 2mm sieve to ensure that the mass of medicinal material debris and impurities after screening is ≤3%.

[0033] In the above embodiments, any actions not described in detail shall be performed in accordance with the descriptions in the Chinese Pharmacopoeia.

[0034] Research on the advantages of the new process compared to the traditional process: Materials are issued from the warehouse and divided into three batches according to the production sequence: 20260101, 20260102, and 20260201, which are produced using the new process; and three batches according to the production sequence: 20250902, 20250802, and 20250701, which are produced using the traditional process.

[0035] After each batch of production is completed, random sampling is conducted, and the samples from each batch are tested according to the requirements of the Chinese Pharmacopoeia. Table 1 below shows some of the relevant quantitative test data. Table 1

[0036] Data Analysis and Conclusions The data in the table above shows that both the new and traditional processes meet the requirements of the Chinese Pharmacopoeia, which stipulate that the moisture content should not exceed 13.0%, the total ash content should not exceed 9.0%, and the water-soluble extract content should not be less than 5.0%. Comparing the water-soluble extract indicators of different batches, it can be seen that the average water-soluble extract content using the new process is approximately 18% higher than that using the traditional process. In other words, the processed Pinellia ternata using the new process has better medicinal efficacy.

[0037] According to the applicant's analysis, the reasons for this phenomenon are as follows: Unlike traditional processes, this application breaks down the softening and soaking process into three stages: high-temperature soaking, low-temperature soaking, and medium-temperature soaking. The high-temperature soaking stage rapidly softens the superficial tissue of Pinellia ternata; the low-temperature soaking stage eliminates the starch gelatinization that might be caused by the high-temperature soaking, inhibits microbial activity, shrinks the surface tissue of Pinellia ternata, and restricts the release of effective components from within, thus softening the middle tissue; finally, the medium-temperature soaking stage softens the inner tissue. Although the number of process steps increases, the overall soaking time is still shorter than that of traditional processes due to the presence of high-temperature soaking and the shorter low-temperature soaking time. Furthermore, it restricts the release of effective components from Pinellia ternata, contributing to improved quality of the final product.

[0038] The drying process was adjusted to gradient drying. The initial low temperature and high humidity environment prevents the surface from hardening instantly and hinders the leakage of internal moisture. Then, the temperature is gradually increased and the humidity is reduced to accelerate drying, effectively avoiding the loss of effective components of medicinal materials caused by traditional high temperature and fast drying.

[0039] In contrast, the traditional process involves static soaking, which relies mainly on the natural penetration of the soaking solution. Because dried Pinellia ternata has a relatively dense texture, the soaking solution takes a long time to reach the center of the Pinellia ternata. During this process, the superficial tissues of Pinellia ternata are in contact with the soaking solution for a long time, causing the effective components to be released into the soaking solution, thus affecting the quality of the final product.

[0040] Obviously, the above embodiments of this application are merely examples for clear illustration and are not intended to limit the implementation of the application. Those skilled in the art can make other variations or modifications based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this application should be included within the scope of protection of the claims of this application.

Claims

1. A method for processing Pinellia ternata, characterized in that, Includes the following steps: (1) After cleaning Pinellia ternata, place it in a container and soak it in a soaking solution at 35-45 degrees Celsius for 12-16 hours to soften the superficial tissue of Pinellia ternata. During the soaking process, keep the temperature of the soaking solution constant. (2) After the high-temperature soaking is completed, drain the soaking solution and soak in a 10-15 degree Celsius soaking solution for 6-8 hours to stabilize the tissue structure of Pinellia ternata, shrink the surface tissue of Pinellia ternata, restrict the release of effective components inside Pinellia ternata, and soften the middle tissue of Pinellia ternata. During the soaking process, keep the temperature of the soaking solution constant. (3) After the low-temperature soaking is completed, drain the soaking solution and soak in a medium-temperature soaking solution of 20-25 degrees Celsius to soften the inner tissue of Pinellia ternata until there is no white core inside Pinellia ternata. Keep the temperature of the soaking solution constant during the soaking process. (4) After the medium-temperature soaking is completed, drain the soaking solution and soak it in a mixture of licorice juice and lime water at 20-25 degrees Celsius until the cross-section of Pinellia ternata is uniformly yellow and has a slightly numbing sensation on the tongue. During the process, maintain the concentration and pH value of the mixture and stir. (5) After the detoxification soaking is completed, wash the Pinellia ternata, and then dry and screen it to obtain processed Pinellia ternata.

2. The processing method of Pinellia ternata according to claim 1, characterized in that, The specific process of purifying Pinellia ternata involves removing impurities, as well as deteriorated, insect-infested, and moldy products, ensuring that the impurities in the purified medicinal material are ≤3%, separating them by size, weighing them, and obtaining purified Pinellia ternata.

3. The processing method of Pinellia ternata according to claim 1, characterized in that, During the soaking process, the liquid level is 8-12 cm higher than the material, and stirring is also performed.

4. The processing method of Pinellia ternata according to claim 1, characterized in that, The specific preparation process of the licorice juice and lime water mixture is as follows: Prepare licorice and quicklime according to the mass ratio of Pinellia ternata: licorice: quicklime = 100: 15: 10; Cut the licorice root into 10-15 mm segments or 2-4 mm slices, place them in an extraction tank, add water and decoct twice. For the first decoction, add 8 times the weight of water, soak for 0.5-1 hour, and decoct for 1.5 hours. For the second decoction, add 7 times the weight of water and decoct for 1 hour. Filter, combine the filtrates, and concentrate them in a cooking pot to 1.5-2.2 times the weight of the net Pinellia ternata. Set aside for use. Take 0.1 times the weight of the cleaned Pinellia ternata and place it in a container. Add water, soak briefly, and stir until it is completely dissolved. Set aside for later use. The product is obtained by mixing licorice juice and lime water.

5. The processing method of Pinellia ternata according to claim 1, characterized in that, The drying process specifically involves: spreading the washed medicinal materials evenly on a tray to a thickness of 2-4 cm, and drying them in a gradient of 50-65°C. The initial drying temperature is 50°C, and the temperature is increased by 5°C every 2 hours. Once the temperature reaches 65°C, it is maintained at a constant temperature until the moisture content of the medicinal materials is ≤13%.

6. The processing method of Pinellia ternata according to claim 1, characterized in that, The screening process specifically involves using a 2mm sieve to ensure that the mass of medicinal material debris and impurities after screening is ≤3%.

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