A traditional Chinese medicine composition, a preparation method and application thereof
Patent Information
- Application Number
- CN202410380118.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-30
- Publication Date
- 2026-09-29
AI Technical Summary
[0003]目前治疗脑梗塞一般采用的治疗方法是西医的以脑血管扩张剂、抗凝剂及血栓溶解剂治疗脑血栓后遗症在治疗老年患者的脑梗塞其溶栓时会有加大继发出血的风险,且溶栓治疗的时间窗要求严格,造成溶栓对大部分病人的治疗出现技术上障碍,影响预防后及生存质量;
[0023]本发明与现有技术相比的优点在于:本发明所提供的中药组合物组方合理,通过桂叶油、红花、冬青油、樟脑、血竭、薄荷脑、松节油、桉油、丁香油、牛大力、杜仲、肉桂油的合理配伍,所加工制备而得的成品可用于制备治疗脑梗塞后遗症药物,具有益气活血,开窍止痛的功效,可用于治疗脑梗塞后遗症、预防脑梗塞。
Abstract
Description
Technical Field
[0001] This invention relates to the field of traditional Chinese medicine technology, specifically to a traditional Chinese medicine composition, its preparation method, and its application. Background Technology
[0002] Post-stroke sequelae refer to the presence of symptoms such as hemiplegia, speech impairment, or facial paralysis one year after the onset of a stroke. This period is also called the post-stroke sequelae period, and the recovery speed and extent are slower compared to the recovery period. The main symptoms include hemiplegia, unilateral limb dysfunction, limb numbness, hemianopsia, and aphasia. Other symptoms may include crossed paralysis, crossed sensory disturbances, external oculomotor palsy, nystagmus, dysarthria, speech impairment, memory loss, facial paralysis, dysphagia, choking, ataxia, dizziness, and headache. The root cause lies in blood disorders such as high blood viscosity, high blood lipids, high blood pressure, high blood sugar, and platelet aggregation within the cerebral blood vessels, as well as vascular lesions such as atherosclerotic plaque formation. The combined effect of these two conditions results in thrombi that block cerebral arteries, leading to interruption of local blood flow and cerebral ischemia and hypoxia.
[0003] Currently, the common treatment for cerebral infarction is Western medicine, which uses cerebral vasodilators, anticoagulants, and thrombolytic agents to treat the sequelae of cerebral thrombosis. However, when treating cerebral infarction in elderly patients, thrombolysis may increase the risk of secondary bleeding, and the time window for thrombolytic therapy is strictly required, which makes thrombolysis a technical obstacle for the treatment of most patients, affecting prevention and quality of life.
[0004] Therefore, traditional Chinese medicine is a better treatment option for the sequelae of cerebral infarction because it is safe, effective, and has few side effects. Summary of the Invention
[0005] The technical problem to be solved by the present invention is to overcome the defects of the above-mentioned technology and provide a traditional Chinese medicine composition, its preparation method and application.
[0006] To solve the above-mentioned technical problems, the present invention provides a traditional Chinese medicine composition and its preparation method and application. The traditional Chinese medicine composition is composed of the following raw materials in parts by weight: 0.16-0.2 g of cinnamon leaf oil, 0.08-0.1 g of safflower, 18-18.04 g of wintergreen oil, 7.6-7.7 g of camphor, 0.1-0.14 g of dragon's blood, 20.30-20.32 g of menthol, 7.4-7.44 g of turpentine oil, 5.4-5.44 g of eucalyptus oil, 2.1-2.2 g of clove oil, 0.4-0.46 g of *Smilax glabra*, 0.14-0.144 g of *Eucommia ulmoides*, and 0.2-0.24 g of cinnamon oil.
[0007] Furthermore, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 0.18g of cinnamon leaf oil, 0.09g of safflower, 18.02g of wintergreen oil, 7.65g of camphor, 0.12g of dragon's blood, 20.31g of menthol, 7.42g of turpentine oil, 5.42g of eucalyptus oil, 2.15g of clove oil, 0.43g of *Smilax glabra*, 0.142g of *Eucommia ulmoides*, and 0.22g of cinnamon oil.
[0008] The second objective of this invention is to provide a method for preparing the traditional Chinese medicine composition, comprising the following steps: taking cinnamon leaf oil, safflower, wintergreen oil, camphor, dragon's blood, menthol, turpentine oil, eucalyptus oil, clove oil, eucalyptus oil, eucommia bark, and cinnamon oil in parts by weight respectively, and then putting them into a container and stirring them thoroughly to obtain the finished product.
[0009] A third objective of this invention is to provide the application of the aforementioned traditional Chinese medicine composition in the preparation of a drug for treating sequelae of cerebral infarction.
[0010] The raw materials used in this invention are sourced from the following sources:
[0011] Cinnamon leaf oil: It is hot in nature and pungent in taste; it enters the lung, spleen and kidney meridians; it has the effects of tonifying fire and assisting yang, guiding fire back to its source, dispelling cold and relieving pain, and promoting blood circulation and regulating menstruation.
[0012] Safflower: It has a pungent taste and warm properties; it enters the heart and liver meridians; it invigorates blood circulation, promotes menstruation, disperses blood stasis, and relieves pain; it is used for amenorrhea, dysmenorrhea, lochia retention, abdominal masses, chest pain, abdominal pain due to blood stasis, chest and rib pain, traumatic injuries, and sores and swelling.
[0013] Wintergreen oil: Medicinal wintergreen oil is an essential oil extracted from the leaves and fruits of the wintergreen tree. It has a variety of effects, including antibacterial, antiviral, analgesic, anti-inflammatory and antioxidant properties.
[0014] Camphor: It has a pungent taste and warm properties; it enters the heart and spleen meridians; it clears the orifices, promotes qi circulation, dispels foulness, kills parasites and relieves itching, reduces swelling and relieves pain; it is used for fever with delirium, sudden collapse due to sudden illness, abdominal pain due to heatstroke, vomiting and diarrhea, cold and damp beriberi, scabies and stubborn tinea, tinea capitis, frostbite, leg ulcers, burns, sprains and bruises, toothache, and conjunctivitis.
[0015] Dragon's Blood: Sweet, salty, neutral; enters the heart and liver meridians; invigorates blood and relieves pain, removes blood stasis and stops bleeding, promotes wound healing and tissue regeneration; used for traumatic injuries, abdominal pain due to blood stasis, external bleeding, and non-healing sores.
[0016] Menthol: It has a pungent taste and a cooling nature; it dispels wind and clears heat; it is mainly used for wind-heat colds, headaches, red eyes, sore throats, toothaches, and itchy skin.
[0017] Turpentine oil: a volatile oil obtained through distillation or extraction from the oleoresin exuded by several plants in the genus *Pinus* of the family Pinaceae. It has the effects of promoting blood circulation, reducing swelling, and relieving pain. It is mainly used to treat joint swelling and pain, muscle pain, and injuries from falls and blows.
[0018] Eucalyptus oil: is the volatile oil obtained by steam distillation from *Eucalyptus globulus* Labill. of Myrtaceae, *Cinnamomum camphora* (L.) Sieb. of Lauraceae, or other plants of the same genera belonging to the above two families. Its functions and indications are: dispelling wind and alleviating pain. It is used for skin pruritus and neuralgia.
[0019] Clove oil: pungent and sweet in flavor, warm in nature; acts on spleen, stomach and kidney meridians; warms the stomach, checks adverse qi, warms the kidney and alleviates pain; used for stomach cold distending pain, hiccup, hematemesis, arthralgia pain, hernial pain, halitosis and toothache.
[0020] Radix Millettiae Speciosae: sweet in flavor, neutral in nature; acts on kidney and lung meridians; tonifies deficiency and moistens lung, strengthens tendons and activates collaterals; used for lumbar muscle strain, rheumatoid arthritis, treats lung heat, lung deficiency cough, pulmonary tuberculosis, chronic bronchitis, chronic hepatitis, spermatorrhea and leukorrhagia.
[0021] Eucommiae Cortex: sweet and slightly pungent, warm; acts on liver and kidney meridians; tonifies liver and kidney, strengthens muscles and bones, prevents abortion; treats soreness and pain of waist and spine, weakness of feet and knees, dribbling urination, dampness and itching under the vulva, threatened abortion, restless fetus motion and hypertension.
[0022] Cinnamon oil: pungent and sweet in flavor, warm in nature; acts on spleen and stomach meridians; dispels wind-damp, warms and invigorates spleen and stomach; used for rheumatism, skin pruritus, yang exhaustion of spleen and stomach, cold limbs and faint pulse, cold accumulation in epigastrium and abdomen, abdominal pain and diarrhea, cold hernia and other diseases.
[0023] Compared with the prior art, the advantages of the present invention are: the traditional Chinese medicine composition provided by the present invention has a reasonable formula. Through reasonable compatibility of cinnamon leaf oil, safflower, wintergreen oil, camphor, dragon's blood, menthol, turpentine, eucalyptus oil, clove oil, radix millettiae speciosae, eucommiae cortex and cinnamon oil, the finished product processed and prepared can be used for preparing medicine for treating sequelae of cerebral infarction, has the effects of supplementing qi, activating blood circulation, inducing resuscitation and alleviating pain, and can be used for treating sequelae of cerebral infarction and preventing cerebral infarction. Detailed Description of Embodiments
[0024] A traditional Chinese medicine composition, preparation method and application thereof according to the present invention will be further described in detail below with reference to embodiments.
[0025] Example 1
[0026] A traditional Chinese medicine composition, which consists of the following raw materials by weight: 0.18 g of cinnamon leaf oil, 0.09 g of safflower, 18.02 g of wintergreen oil, 7.65 g of camphor, 0.12 g of dragon's blood, 20.31 g of menthol, 7.42 g of turpentine, 5.42 g of eucalyptus oil, 2.15 g of clove oil, 0.43 g of radix millettiae speciosae, 0.142 g of eucommiae cortex, and 0.22 g of cinnamon oil;
[0027] The preparation method of the traditional Chinese medicine composition includes the following steps: taking cinnamon leaf oil, safflower, wintergreen oil, camphor, dragon's blood, menthol, turpentine oil, eucalyptus oil, clove oil, oxalis, eucommia, and cinnamon oil in parts by weight respectively, and then putting them into a container and stirring them thoroughly to obtain the finished medicine.
[0028] How to use:
[0029] When using this product, first shave the patient's head hair, then apply the finished product to their head and massage it in to allow the medicine to slowly penetrate into their cranial cavity. Finally, use auxiliary equipment for heat therapy to enhance the penetration of the medicine, allowing it to penetrate deep into the brain and maximize its efficacy. This helps to clear the blood vessels in the brain, dissipate accumulated blood stasis, and repair damaged brain nerves and brain tissue (pyramidal tract), ultimately restoring motor function.
[0030] The present invention and its embodiments have been described above, and such description is not restrictive. In conclusion, if those skilled in the art are inspired by this description and design similar structures and embodiments without departing from the spirit of the invention, such designs should fall within the protection scope of the present invention.
Claims
1. A traditional Chinese medicine composition, characterized in that, The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 0.16-0.2 g of cinnamon leaf oil, 0.08-0.1 g of safflower, 18-18.04 g of wintergreen oil, 7.6-7.7 g of camphor, 0.1-0.14 g of dragon's blood, 20.30-20.32 g of menthol, 7.4-7.44 g of turpentine oil, 5.4-5.44 g of eucalyptus oil, 2.1-2.2 g of clove oil, 0.4-0.46 g of *Smilax glabra*, 0.14-0.144 g of *Eucommia ulmoides*, and 0.2-0.24 g of cinnamon oil.
2. The traditional Chinese medicine composition according to claim 1, characterized in that, The traditional Chinese medicine composition consists of the following raw materials in parts by weight: 0.18g of cinnamon leaf oil, 0.09g of safflower, 18.02g of wintergreen oil, 7.65g of camphor, 0.12g of dragon's blood, 20.31g of menthol, 7.42g of turpentine oil, 5.42g of eucalyptus oil, 2.15g of clove oil, 0.43g of *Smilax glabra*, 0.142g of *Eucommia ulmoides*, and 0.22g of cinnamon oil.
3. The method for preparing the traditional Chinese medicine composition according to any one of claims 1-2, characterized in that, The process includes the following steps: Take the following ingredients by weight: laurel leaf oil, safflower, wintergreen oil, camphor, dragon's blood, menthol, turpentine oil, eucalyptus oil, clove oil, oxalis root, eucommia bark, and cinnamon oil, and then put them into a container and stir them thoroughly to obtain the finished product.
4. The use of a traditional Chinese medicine composition as described in any one of claims 1-2 in the preparation of a drug for treating sequelae of cerebral infarction.