A suction catheter for suctioning an eccentric thrombus

Abstract

The application provides a suction catheter for suctioning eccentric thrombus, and belongs to the technical field of interventional medical instruments. The suction catheter for suctioning eccentric thrombus comprises a suction catheter body, an inner cavity of the suction catheter body constitutes a suction passage, a suction port in communication with the suction passage is arranged at the distal end of the suction catheter body, a balloon is coaxially arranged on the outer side wall of the suction catheter body at a position with a certain distance from the suction port, one side of the balloon is provided with an inflation adjusting component, and the inflation adjusting component is arranged on the inner side and / or the outer side of the balloon along the axial extension direction, so as to adjust the inflation degree of part of the balloon during the inflation of the balloon, so that the balloon is inflated into an eccentric shape, the side with larger inflation of the balloon is located on the side opposite to the suction object, and then the suction port is driven to be close to the suction object. The technical problem that the balloon catheter in the prior art is difficult to effectively suction eccentric thrombus is solved.

Description

Technical Field

[0001] This invention belongs to the field of interventional medical device technology, specifically relating to an aspiration catheter for aspirating eccentric thrombi. Background Technology

[0002] Thrombus aspiration, as a minimally invasive interventional treatment technique, has become a common treatment method for quickly relieving vascular blockages and saving patients' lives due to its advantages of not requiring surgery, minimal trauma, and rapid recovery. It is widely used in the emergency treatment of acute ischemia caused by thrombosis. This procedure involves inserting a specialized balloon catheter into the blood vessel, using balloon dilation to temporarily block the vessel. Simultaneously, a negative pressure device connected to the proximal end of the catheter creates negative pressure at the distal aspiration port, drawing out the thrombus from the blood vessel. This rapidly restores blood flow to the affected area, minimizing necrosis of vital organs caused by ischemia and reducing long-term disability and mortality rates.

[0003] Currently, the basic structure of commonly used thrombus aspiration catheters in clinical practice typically includes a catheter body, a balloon located at the distal end of the catheter body, and an aspiration channel. The aspiration port of the aspiration channel is located at the distal end of the catheter body. During the actual surgical procedure, medical staff first advance the balloon catheter along the guidewire to the blood vessel where the thrombus is located. Then, the balloon is inflated. The inflated balloon adheres tightly to the inner wall of the blood vessel, providing support and fixation for the vessel, preventing catheter displacement during aspiration, and simultaneously blocking local blood flow to facilitate negative pressure aspiration of the thrombus.

[0004] However, existing traditional thrombectomy balloon catheters have significant technical limitations when aspirating eccentric thrombi, severely impacting aspiration effectiveness and surgical efficiency. Eccentric thrombi, characterized by being attached to one side of the vessel wall, are non-central and do not completely obstruct the lumen. Their main feature is that they adhere to one side of the vessel wall while blood flow continues on the other side, presenting as a crescent-shaped or semi-lunar filling defect on imaging. This type of thrombus is relatively common in clinical practice, especially in lesions of the pulmonary artery, coronary artery, and carotid artery.

[0005] Traditional aspiration catheters used for removing eccentric thrombi have a symmetrical, ring-shaped balloon. When the balloon is inflated, it applies a uniform supporting force to the vessel wall in all directions, thus centering the entire catheter within the vessel lumen and ensuring that the aspiration port at the distal end of the catheter is simultaneously centered within the vessel lumen. However, eccentric thrombi adhere to one side of the vessel wall, offset from the center of the vessel lumen. In this case, a significant spatial gap forms between the centered aspiration port and the eccentric thrombus. The negative pressure suction force is insufficient to effectively act on the surface of the eccentric thrombus, resulting in a significant reduction in aspiration efficiency, or even the inability to successfully remove the eccentric thrombus.

[0006] To address these issues, medical staff often need to repeatedly adjust the catheter position and inflate / deflate the balloon to try and bring the aspiration port closer to the eccentric thrombus. This not only prolongs the procedure time and increases the risk of surgical trauma and complications for the patient, but also risks thrombus dislodgement due to repeated manipulation, leading to serious adverse consequences such as distal vascular embolism and endangering the patient's life. Therefore, an improved technical solution is needed to address the shortcomings of existing technologies. Summary of the Invention

[0007] The purpose of this invention is to provide an aspiration catheter for aspirating eccentric thrombi, so as to solve the technical problem that existing aspiration catheters for aspirating eccentric thrombi are difficult to effectively aspirate eccentric thrombi.

[0008] To achieve the above objectives, the aspiration catheter for aspirating eccentric thrombi of the present invention provides the following technical solution:

[0009] An aspiration catheter for aspirating eccentric thrombi includes an aspiration catheter body, the inner lumen of which forms an aspiration channel, and a distal end of the aspiration catheter body having an aspiration port communicating with the aspiration channel. A balloon is coaxially arranged on the outer wall of the aspiration catheter body at a predetermined distance from the aspiration port. One side of the balloon has an expansion adjustment component, which is arranged along the axial extension direction on the inner and / or outer side of the balloon. The expansion adjustment component is used to adjust the degree of inflation of part of the balloon during inflation, so that the balloon inflates into an eccentric shape, with the side of the balloon with greater inflation located on the side opposite to the aspiration target, thereby driving the aspiration port closer to the aspiration target.

[0010] As a further optimized technical solution, the expansion adjustment component is a tie structure arranged inside the balloon, with one side of the tie structure fixedly connected to the inner wall of the balloon and the other side fixedly connected to the outer wall of the aspiration catheter body.

[0011] As a further optimized technical solution, multiple tie structures are arranged, and each tie structure has through holes at both ends between its ends and the inner wall of the balloon for the filling medium to pass through.

[0012] As a further optimized technical solution, the through holes at both ends of each of the tie structures have the same axial dimension.

[0013] As a further optimized technical solution, at least one of the tie structures has an internal filling cavity, which is used to support the aspiration catheter body inside the balloon to adjust the height of the aspiration port.

[0014] As a further optimized technical solution, the inflation adjustment component is a limiting structure arranged on the outside of the balloon. The two ends of the limiting structure are fixedly connected to the two ends of the balloon, and the middle part is attached to the outside of the balloon to limit the inflation degree of the balloon.

[0015] As a further optimized technical solution, the middle part of the limiting structure is an arc-shaped sleeve that adapts to the outer side of the balloon.

[0016] As a further optimized technical solution, at least one end of the balloon is provided with a imaging component to display the balloon's inflation state.

[0017] As a further optimized technical solution, the developing component is arranged on the side close to the expansion adjustment component or the side thereof.

[0018] As a further optimized technical solution, the end face edge of the suction port has an arc-shaped chamfer.

[0019] Beneficial Effects: Because this invention incorporates an expansion adjustment component on one side of the balloon, this component selectively restricts the radial expansion of one side of the balloon during inflation. This causes the balloon to no longer maintain a traditional concentric expansion, but instead form an eccentric shape. The side facing away from the aspiration target (eccentric thrombus) expands more significantly, while the side facing the target expands less. This eccentric expansion shape causes the aspiration catheter and aspiration port to shift towards the thrombus location, bringing the aspiration port closer to the surface of the eccentric thrombus. Compared to existing technologies where the aspiration port is always located in the center of the blood vessel with a large gap between it and the eccentric thrombus, this invention significantly shortens the distance between the aspiration port and the thrombus, increases the direct force of negative pressure aspiration, thereby greatly improving the aspiration efficiency and clearance success rate of eccentric thrombi, reducing repeated adjustments during surgery, lowering the risk of thrombus dislodgement, shortening surgical time, and improving patient prognosis.

[0020] Furthermore, when the expansion adjustment component employs a tie structure arranged inside the balloon, this structure directly exerts a pulling constraint on a specific area inside the balloon, thereby controlling the degree of balloon expansion on that side. By setting multiple tie structures and forming through holes at both ends, both the deterministic nature of the constraint and the free flow of the filling medium inside the balloon are ensured, allowing the balloon to quickly and uniformly reach the predetermined eccentric shape, thus avoiding instability caused by uneven local expansion.

[0021] Furthermore, when at least one tie structure has an independently inflatable filling cavity, during the procedure, depending on the actual thrombus location and vascular morphology, the tie structure can be expanded by injecting a medium into the filling cavity a second time. This allows the aspiration catheter body located inside the balloon to bend away from the thrombus. At this time, the aspiration catheter body as a whole does not deform, thus allowing the aspiration port to move closer to the thrombus location. This enables adjustment of the height and proximity of the aspiration port, significantly improving adaptability to complex eccentric thrombi.

[0022] Furthermore, when the expansion adjustment component is a restraining structure arranged on the outside of the balloon, and its central part is an arc-shaped sleeve adapted to the outside of the balloon, this external restraint method does not occupy the internal space of the balloon and is convenient for manufacturing. At the same time, the outer arc-shaped sleeve can be made of the same compliant material as the balloon, which makes it easy to achieve product consistency and large-scale production.

[0023] Furthermore, by placing a contrast-enhancing component at at least one end of the balloon and setting a distinction on the side near the expansion adjustment component, the doctor can clearly and intuitively determine the balloon's eccentricity under X-ray, accurately identifying the side of the balloon with greater expansion (the side with the aspiration port offset). This solves the problem of difficulty in determining the asymmetrical shape of the balloon in vivo in existing technologies, allowing the operator to purposefully rotate the catheter to ensure that the side with greater expansion faces away from the eccentric thrombus, further improving the controllability and success rate of the procedure.

[0024] Furthermore, by setting an arc-shaped chamfer at the distal end edge of the aspiration port, the scraping, cutting, or impact on the inner wall of the blood vessel can be reduced when the aspiration catheter is advanced or rotated, thereby reducing the probability of complications such as vascular perforation and dissection. At the same time, when passing through curved, calcified, or narrowed lesion segments, the smooth arc-shaped chamfer can reduce the resistance between the distal end of the catheter and the surface of the blood vessel wall or plaque, making it easier for the catheter to reach the target thrombus location and reducing the occurrence of jamming. Attached Figure Description

[0025] The accompanying drawings, which form part of this application, are used to provide a further understanding of the invention. The illustrative embodiments of the invention and their descriptions are used to explain the invention and do not constitute an undue limitation of the invention. Wherein:

[0026] Figure 1 This is a schematic diagram of the overall structure of the aspiration catheter for aspirating eccentric thrombi according to Embodiment 1 of the present invention. At this time, the balloon is inflated.

[0027] Figure 2 This is a schematic cross-sectional view along the axial direction of the balloon of Embodiment 1 of the aspiration catheter for aspirating eccentric thrombi of the present invention.

[0028] Figure 3 This is a radial cross-sectional schematic diagram of the balloon of Embodiment 1 of the aspiration catheter for aspirating eccentric thrombi of the present invention.

[0029] Figure 4 This is an axial cross-sectional view of the filling lumen of the aspiration catheter of embodiment 1 for aspirating eccentric thrombi of the present invention after it has been filled.

[0030] Figure 5 This is a radial cross-sectional view of the filling lumen of the aspiration catheter of embodiment 1 for aspirating eccentric thrombi of the present invention after it has been filled.

[0031] Figure 6 This is a schematic diagram of a working state of an embodiment 1 of the aspiration catheter for aspirating eccentric thrombi according to the present invention;

[0032] Figure 7 This is a first schematic diagram of another working state of the aspiration catheter of the present invention for aspirating eccentric thrombi;

[0033] Figure 8 This is a second schematic diagram of another working state of the aspiration catheter of embodiment 1 for aspirating eccentric thrombi according to the present invention;

[0034] Figure 9 This is a schematic diagram of a working state of an embodiment 2 of the aspiration catheter for aspirating eccentric thrombi according to the present invention;

[0035] Figure 10 This is a radial cross-sectional schematic diagram of the balloon of Embodiment 2 of the aspiration catheter for aspirating eccentric thrombi of the present invention.

[0036] Figure 11 This is a radial cross-sectional schematic diagram of the balloon of Embodiment 3 of the aspiration catheter for aspirating eccentric thrombi of the present invention.

[0037] Figure 12 This is a schematic diagram of the distal structure of the aspiration catheter of the present invention for aspirating eccentric thrombi in Embodiment 4;

[0038] Figure 13 This is a schematic diagram of the distal structure of Embodiment 5 of the aspiration catheter for aspirating eccentric thrombi according to the present invention.

[0039] In the figure: 100, aspiration catheter body; 110, aspiration channel; 111, aspiration port; 120, balloon; 121, expansion adjustment component; 122, through hole; 123, filling chamber; 130, connecting valve; 140, first filling channel; 150, second filling channel; 160, connecting layer; 170, imaging component. Detailed Implementation

[0040] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention are within the scope of protection of the present invention.

[0041] In the description of this invention, the terms "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," and "bottom," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing the invention and do not require the invention to be constructed and operated in a specific orientation; therefore, they should not be construed as limitations on the invention. The terms "connected" and "linked" used in this invention should be interpreted broadly. For example, they can refer to a fixed connection or a detachable connection; they can refer to a direct connection or an indirect connection through intermediate components. Those skilled in the art can understand the specific meaning of the above terms according to the specific circumstances. Furthermore, the term "proximal end" uniformly refers to the end closer to the operator, while "distal end" refers to the end farther from the operator.

[0042] The present invention will now be described in detail with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described herein can be combined with each other.

[0043] The shapes and sizes of the components in the accompanying drawings do not reflect the actual proportions of the product; they are only intended to illustrate the content of the invention.

[0044] This invention provides an aspiration catheter for aspirating eccentric thrombi, which mainly solves the technical problem of existing thrombus aspiration catheters where the aspiration port is located in the center of the blood vessel due to the symmetrical expansion of the balloon, making it difficult to effectively aspirate eccentric thrombi. The aspiration catheter for aspirating eccentric thrombi includes an aspiration catheter body 100, the inner lumen of which forms an aspiration channel 110, and an aspiration port 111 communicating with the aspiration channel 110 at the distal end of the aspiration catheter body 100. A balloon 120 is coaxially arranged on the outer wall of the aspiration catheter body 100 at a set distance from the aspiration port. The key feature of this invention is that an expansion adjustment component 121 is arranged on one side of the axis of the balloon 120. The expansion adjustment component 121 is arranged axially on the inner and / or outer side of the balloon 120 and is used to adjust the degree of expansion of part of the balloon 120 during the inflation process, so that the balloon 120 expands into an eccentric shape, and the side with greater expansion faces away from the aspiration object (eccentric thrombus), thereby driving the aspiration port 111 to shift towards the thrombus side and get closer to the thrombus. The expansion adjustment component 121 can employ an internal tie structure (achieving eccentricity by constraining expansion on one side) or an external restriction structure (achieving eccentricity by constraining expansion in a specific area), or a combination of both. It can also work with the imaging component 170 to display the eccentric shape of the balloon 120 after inflation in real time. Furthermore, the edge of the aspiration port 111 of this invention is also equipped with an arc-shaped chamfer to improve the safety of the catheter during its travel along the blood vessel. This invention, through its asymmetric eccentric balloon structure, allows the aspiration port to actively approach the eccentric thrombus, significantly improving aspiration efficiency and success rate, reducing repeated intraoperative adjustments, and lowering the risk of thrombus dislodgement. It is suitable for aspiration treatment of eccentric thrombi in blood vessels, such as those in acute ischemic stroke.

[0045] Example 1

[0046] like Figure 1 As shown, the aspiration catheter for aspirating eccentric thrombi is mainly used for the aspiration and removal of eccentric thrombi within blood vessels. Specifically, the catheter includes a slender, flexible aspiration catheter body 100, with an axially extending aspiration channel 110 inside. Aspiration port 111 is located at the distal end of the aspiration catheter body 100, which communicates with the aspiration channel 110 for aspirating the thrombus under negative pressure. A connecting valve 130 is located at the proximal end of the aspiration catheter body 100, and has three branch structures. One branch structure communicates with the proximal end of the aspiration channel 110 for connecting to an external negative pressure aspiration device to provide negative pressure to the aspiration channel 110. The functions of the other two branch structures will be described in detail below.

[0047] An inflatable balloon 120 is coaxially fitted on the outer wall of the aspiration catheter body 100, at a distance of 5-15 mm (the exact size varies depending on the catheter model) from the aspiration port 111. It should be noted that the description of the balloon 120 as "coaxially" positioned on the aspiration catheter body 100 here refers to the balloon 120 maintaining a coaxial position with the aspiration catheter body 100 during manufacturing, i.e., in its non-inflated state, not that it remains coaxial even when inflated.

[0048] Both ends of the balloon 120 are fixedly and sealed to the outer wall of the aspiration catheter body 100. A first filling channel 140 is provided inside the wall of the aspiration catheter body 100. Its proximal end is connected to a branch structure on the connecting valve 130 for connecting an external filling device, and its distal end opens in the internal region of the balloon 120 for filling the balloon 120 with a filling medium (such as gas or contrast agent).

[0049] An expansion adjustment component 121 is disposed inside the balloon 120. In this embodiment, the expansion adjustment component 121 is a tie-in structure made of a polymer material (such as nylon or polyurethane) or elastomer with a certain degree of flexibility. One side of the tie-in structure is fixedly connected to the inner wall of the balloon 120 (e.g., by bonding or integral molding), and the other side is fixedly connected to the outer wall of the aspiration catheter body 100 through a connecting layer 160.

[0050] like Figure 2 and Figure 3 As shown, when the filling medium is injected into the balloon 120 through the first filling channel 140, due to the traction of the tie structure, the radial expansion of the balloon 120 on the side connected to the tie structure is restricted, while the opposite side (i.e., the side without the tie structure) can expand freely. Ultimately, the balloon 120 exhibits an eccentric shape: the side farther from the tie structure expands more significantly, while the side closer to the tie structure expands less significantly. During the procedure, by rotating the aspiration catheter body 100, the side of the balloon 120 with greater expansion is positioned away from the eccentric thrombus (i.e., the aspiration target), while the side with less expansion remains on the same side as the eccentric thrombus. At this time, the aspiration port 111 will shift towards the thrombus side due to the asymmetrical state of the balloon 120, thus approaching the thrombus.

[0051] In this embodiment, three tie structures are provided, spaced apart along the circumference of the balloon 120, with the area restricted by all tie structures occupying one-quarter of the overall circumference of the balloon 120. Furthermore, the two ends of each tie structure are not completely closed, but rather form through holes 122 between them and the inner wall of the balloon 120. This through hole design has two important functions. Firstly, the through hole 122 allows the filling medium to flow between different areas inside the balloon 120, ensuring that the balloon 120 can be inflated uniformly and rapidly. The axial dimensions of the through holes 122 at both ends of each tie structure are preferably the same to ensure uniform tension distribution. Secondly, it ensures that the tie structures are located in the center of the balloon 120. When the tie structure has an inflation cavity 123, the inflation of the inflation cavity 123 will push and bend the aspiration catheter body 100 inside the balloon 120 from the center. This is crucial for adjusting the distance between the aspiration port 111 and the thrombus, and this function will be described in detail below.

[0052] Furthermore, such as Figure 4 and Figure 5 As shown, at least one tie structure is designed to have a hollow interior forming a filling cavity 123. In this embodiment, all three tie structures have hollow interiors forming filling cavities 123. All filling cavities 123 are connected to an external filling device via a second filling channel 150 located within the wall of the aspiration catheter body 100. Specifically, the second filling channel 150 is connected to the external filling device via a branch structure of the connecting valve 130. When it is necessary to fine-tune the height of the aspiration port 111 or move closer to the thrombus during surgery, filling medium can be injected into the filling cavity 123. In the initial stage of injection, the filling cavity 123 undergoes lateral deformation under the support of the filling medium. At this time, the catheter height will first be adjusted towards the thrombus. Then, as the filling medium continues to be injected, the pressure in the filling cavity 123 continues to increase, causing the tie structure itself to expand radially. The expanded tie structure pushes the aspiration catheter body 100 inside the balloon 120 away from the thrombus, causing this part to bend away from the thrombus, such as... Figure 4 As shown, at this point, since the aspiration catheter body 100 as a whole has not deformed, only the part inside the balloon 120 has bent, causing the aspiration port 111 to move further closer to the thrombus. For a detailed description of the deformation process, please refer to [reference needed]. Figure 3 and Figure 5When no filling medium is injected into the filling cavity 123, the tie structure is radially straightened under the action of the filling medium inside the balloon 120. At this time, the tie structure tightens the side of the balloon 120 closest to the thrombus, resulting in a smaller inflation degree on that side of the balloon 120, while the side without the tie structure experiences a larger inflation. This causes the balloon 120 to have an eccentric shape, driving the aspiration port closer to the thrombus side, thus facilitating thrombus aspiration. At this time, the bottom of the aspiration catheter body 100 located in the middle of the balloon 120 is L1 away from the vessel wall. After a portion of the thrombus has been aspirated, the aspiration port 111 has already aspirated the thrombus near the vessel's central axis. The remaining thrombus near the vessel wall is no longer convenient to aspirate. In this case, high-pressure filling medium is injected into the filling cavity 123 through the second filling channel 150, such as... Figure 5 As shown, after the filling cavity 123 is filled, the tie structure expands radially and bends towards the side away from the thrombus (i.e., the side opposite to the thrombus attachment on the vessel wall). Due to the presence of the through holes 122 at both ends of the tie structure, this bending deformation can effectively push the aspiration catheter body 100 from the middle, causing this section of the aspiration catheter body 100 inside the balloon 120 to form an arc shape with its opening facing the thrombus. At this time, the distance from the bottom of the aspiration catheter body 100 located in the middle of the balloon 120 to the opposite vessel wall is denoted as L2, and L2 is significantly greater than L1. This means that the middle part of the aspiration catheter body 100 is pushed away from the thrombus, while the distal aspiration port 111, due to the limitation of the distal position of the balloon 120, will not shift away from the thrombus. Therefore, under the leverage effect, it will further deflect towards the thrombus, thereby achieving efficient aspiration of residual wall-attached thrombi. In this embodiment, the working pressure of the inflation cavity 123 should be 2-4 atm higher than the current inflation pressure of the balloon 120 to ensure that the tie structure can effectively expand and deform despite the internal pressure of the balloon 120. Specifically, the pressure of the balloon 120 is set to 6-8 atm; the working pressure of the inflation cavity 123 is set to 9-12 atm.

[0053] Furthermore, a contrast-enhancing component 170 is arranged at at least one end of the balloon 120, near the expansion adjustment component 121. In this embodiment, the contrast-enhancing component 170 is made of a high-density material, such as a platinum-iridium alloy, gold, or a tungsten wire loop, with a material density significantly higher than that of the surrounding catheter body and balloon material. On the one hand, the high-density characteristic allows the contrast-enhancing component 170 to have higher contrast and visibility under X-ray fluoroscopy, and it can still be clearly visualized even when the blood vessel is tortuous or the catheter is moving rapidly, making it convenient for doctors to track the inflation posture and expansion direction of the balloon 120 in real time. On the other hand, the contrast-enhancing component 170 is arranged on the side near the expansion adjustment component 121, and its relatively large mass gives it a certain inertial guiding effect during the bending of the aspiration catheter body 10. When the aspiration catheter body 100 bends under the drive of the filling cavity 123, the high-density imaging component 170 can provide local weight offset along the bending direction, assisting the catheter body to form a smoother and more controllable bending deformation on that side, thereby enhancing the response speed and positioning accuracy of the aspiration port 111 shifting towards the thrombus side, and further improving the aspiration effect on residual wall-adhering thrombi.

[0054] Furthermore, the end face edge of the aspiration port 111 is provided with an arc-shaped chamfer. This reduces the scraping, cutting, or impact on the inner wall of the blood vessel when the aspiration catheter body 100 is advanced or rotated, thereby reducing the probability of complications such as vascular perforation and dissection. At the same time, when passing through curved, calcified, or narrowed lesion segments, the smooth arc-shaped chamfer can reduce the resistance between the distal end of the aspiration catheter body 100 and the surface of the blood vessel wall or plaque, making it easier for the catheter to reach the target thrombus location and reducing the occurrence of jamming.

[0055] In this embodiment, the aspiration catheter for aspirating eccentric thrombi is used as follows: First, using a conventional interventional procedure, a guiding device (not shown in the figure, such as a common guidewire) is pushed through the vascular puncture point to the location of the eccentric thrombus in the target vessel. Then, the aspiration port 111 at the distal end of the aspiration catheter body 100 is advanced into the vessel along the guiding device until the balloon 120 is close to the thrombus area and the aspiration port 111 is roughly aligned with the segment of the vessel to which the thrombus is attached. At this time, both the balloon 120 and the aspiration port 111 are in a contracted, unexpanded state, facilitating smooth advancement within the vessel.

[0056] like Figure 6As shown, after confirming that the distal end of the catheter has reached the target position through X-ray fluoroscopy, the inflation state of the balloon 120 is determined by observing the position of the imaging component 170, and the adjustment component 121 is adjusted to be on the same side as the thrombus. The connecting valve 130 is operated to inject a predetermined amount of filling medium (such as a mixture of normal saline and contrast agent) into the balloon 120 through the first filling channel 140. During this process, due to the constraint of the inflation adjustment component 121 (i.e., the tie structure), the radial expansion of the balloon 120 on the side closer to the tie structure is restricted, while the side farther from the tie structure expands freely. At this time, the distance between the aspiration port 111 and the eccentric thrombus is significantly shortened, and the aspiration channel 110 is connected to the external negative pressure aspiration device, initiating the initial aspiration of the thrombus.

[0057] After negative pressure aspiration is initiated, the thrombus components that are close to the central axis of the blood vessel and have good mobility are preferentially drawn into the aspiration port 111 and discharged from the body through the aspiration channel 110.

[0058] After the thrombus near the central axis of the blood vessel has been largely aspirated, the remaining thrombus is usually tightly adhered to one side of the vessel wall. At this point, the aspiration port 111 is still some distance from the remaining thrombus, and continued conventional negative pressure aspiration is ineffective. In this situation, the operator injects high-pressure filling medium into the filling chamber 123 through the independent branch structure of the connecting valve 130 via the second filling channel 150. Figure 7 , Figure 8 As shown in the two attached figures, the thrombus is located on different sides of the blood vessel. After the filling lumen 123 is filled, the tie structure expands radially and bends towards the side away from the thrombus (i.e., the side opposite to the blood vessel wall where the thrombus is attached). This bending deformation pushes the aspiration catheter body 100 from the middle, causing this section of the aspiration catheter body 100 inside the balloon 120 to form an arc shape with its opening facing the thrombus. Because the middle of the aspiration catheter body 100 arches away from the thrombus, its distal aspiration port 111 is further deflected towards the thrombus under the leverage effect, achieving aspiration of the remaining wall-attached thrombus. The physician can control the amount of fluid injected into the filling lumen 123 according to the positional change of the imaging component 170, achieving graded and controllable fine-tuning of the offset of the aspiration port 111. Ultimately, complete aspiration of the eccentric thrombus is achieved.

[0059] Example 2

[0060] like Figure 9 and Figure 10As shown, the main difference between this embodiment and Embodiment 1 lies in the structure of the expansion adjustment component 121. In this embodiment, the expansion adjustment component 121 is a restraining structure arranged on the outside of the balloon 120. This restraining structure is made of a non-compliant material (such as PET or nylon), and its two ends are fixedly connected to the two ends of the balloon 120 (e.g., by sleeve or adhesive), while the middle part is attached to the outer wall of the balloon 120. The middle part of the restraining structure is shaped like an arc-shaped sleeve that fits the outside of the balloon 120, but the arc-shaped sleeve does not completely enclose the balloon 120, but covers a portion of the circumference of the balloon 120 (e.g., a 90° range). When the filling medium is injected into the balloon 120, the area covered by the arc-shaped sleeve is constrained by the external constraint, and the expansion degree is limited; while the uncovered area can expand freely. Thus, the balloon 120 also forms an eccentric shape, with the side with greater expansion being the unrestrained side. During operation, by aligning the side with greater expansion toward the eccentric thrombus, the aspiration port 111 can be offset. The advantage of this embodiment is that the external constraint structure does not occupy the internal space of the balloon, and the manufacturing process is relatively simple.

[0061] Example 3

[0062] like Figure 11 As shown, the main difference between this embodiment and Embodiment 1 lies in the structure of the expansion adjustment component 121. In this embodiment, the expansion adjustment component 121 includes a tie structure arranged inside the balloon 120 and a restraining structure arranged outside the balloon 120.

[0063] The inner tie structure is similar to that in Embodiment 1: one side of the tie structure is fixedly connected to the inner wall of the balloon 120, and the other side is fixedly connected to the outer wall of the aspiration catheter body 100, extending axially from the proximal end to the distal end of the balloon 120. During balloon inflation, the inner tie structure exerts a pulling constraint on the side closest to the thrombus, limiting the radial expansion of that side of the balloon. Unlike Embodiment 1, in this embodiment, there is no inflation cavity 123 inside the tie structure.

[0064] The outer restraint structure is similar to that in Example 2: this restraint structure is made of a non-compliant material (such as PET or nylon), with its two ends fixedly connected to the two ends of the balloon 120, and its middle part is an arc-shaped sleeve adapted to the outer side of the balloon 120, attached to the outer wall of the balloon 120. The outer restraint structure covers a portion of the circumference of the balloon 120 (e.g., 90°), and the coverage position corresponds to the arrangement position of the inner tie structure, that is, both are located on the same side of the balloon 120 (closer to the thrombus restraint side).

[0065] Example 4

[0066] like Figure 12As shown, the main difference between this embodiment and Embodiment 1 lies in the structure of the aspiration port at the distal end of the aspiration catheter body 100. In this embodiment, the end face of the aspiration port 111 is no longer perpendicular to the axis of the aspiration catheter body 100, but rather has a set angle with the axis. This inclined aspiration port 111 has a larger opening area, and when the aspiration port 111 shifts towards the thrombus due to the eccentric effect of the balloon 120, the inclined end face can better conform to the vessel wall or thrombus surface, further increasing the contact range with the thrombus and the aspiration efficiency. It should be noted that in this embodiment, the end face of the aspiration port 111 may not have a chamfered edge.

[0067] Example 5

[0068] like Figure 13 As shown, the main difference between this embodiment and Embodiment 4 lies in the structure of the aspiration port at the distal end of the aspiration catheter body 100. In this embodiment, the end face of the aspiration port 111 is different. In this embodiment, an arc-shaped chamfer is provided at the edge position. This reduces scraping, cutting, or impact on the inner wall of the blood vessel when the aspiration catheter body 100 is advanced or rotated, thereby reducing the probability of complications such as vascular perforation and dissection. At the same time, when passing through curved, calcified, or narrowed lesion segments, the smooth arc-shaped chamfer reduces the resistance between the distal end of the aspiration catheter body 100 and the surface of the blood vessel wall or plaque, making it easier for the catheter to reach the target thrombus location and reducing the occurrence of jamming. In summary, this invention forms a complete solution for eccentric thrombi by adjusting the inflation state of the balloon. The various technical features work together to significantly improve aspiration efficiency and surgical success rate, while also taking into account the accuracy and convenience of operation.

[0069] The various embodiments in this specification are described in a progressive manner, with each embodiment focusing on the differences from other embodiments. The same or similar parts between the various embodiments can be referred to each other.

[0070] The aspiration catheter for aspirating eccentric thrombi provided by this invention has been described in detail above. Specific examples have been used to illustrate the principles and implementation methods of this invention. The descriptions of the embodiments above are merely for the purpose of helping to understand the method and core ideas of this invention. It should be noted that those skilled in the art can make various improvements and modifications to this invention without departing from its principles, and these improvements and modifications also fall within the protection scope of the claims of this invention.

Claims

1. An aspiration catheter for aspirating eccentric thrombi, comprising an aspiration catheter body (100), the inner lumen of the aspiration catheter body (100) forming an aspiration channel (110), the distal end of the aspiration catheter body (100) having an aspiration port (111) communicating with the aspiration channel (110), and a balloon (120) coaxially arranged on the outer wall of the aspiration catheter body (100) at a predetermined distance from the aspiration port (111), characterized in that, The balloon (120) has an expansion adjustment component (121) on one side. The expansion adjustment component (121) is arranged on the inner and / or outer side of the balloon (120) along the axial extension direction. It is used to adjust the degree of expansion of part of the balloon (120) during the inflation process so that the balloon (120) expands into an eccentric shape. The side of the balloon (120) with greater expansion is located on the side opposite to the aspiration object, thereby driving the aspiration port (111) closer to the aspiration object.

2. The aspiration catheter for aspirating eccentric thrombi according to claim 1, characterized in that, The expansion adjustment component (121) is a tie structure arranged inside the balloon (120). One side of the tie structure is fixedly connected to the inner wall of the balloon (120), and the other side is fixedly connected to the outer wall of the aspiration catheter body (100).

3. The aspiration catheter for aspirating eccentric thrombi according to claim 2, characterized in that, The tie structure is arranged in multiple ways, and each tie structure has a through hole (122) formed at both ends between the end of the tie structure and the inner wall of the balloon (120) for the filling medium to pass through.

4. The aspiration catheter for aspirating eccentric thrombi according to claim 3, characterized in that, The through holes (122) at both ends of each of the tie structures have the same axial dimension.

5. The aspiration catheter for aspirating eccentric thrombi according to claim 3, characterized in that, At least one of the tie structures has an inflatable cavity (123) inside, which is used to support the aspiration catheter body (100) inside the balloon (120) to adjust the height of the aspiration port (111).

6. The aspiration catheter for aspirating eccentric thrombi according to claim 1, characterized in that, The expansion adjustment component (121) is a restriction structure arranged on the outside of the balloon (120). The two ends of the restriction structure are fixedly connected to the two ends of the balloon (120), and the middle part is attached to the outside of the balloon (120) to limit the degree of expansion of the balloon (120).

7. The aspiration catheter for aspirating eccentric thrombi according to claim 6, characterized in that, The central part of the restrictive structure is an arc-shaped sleeve that fits the outer side of the balloon (120).

8. The aspiration catheter for aspirating eccentric thrombi according to any one of claims 1-7, characterized in that, At least one end of the balloon (120) is provided with a imaging component (170).

9. The aspiration catheter for aspirating eccentric thrombi according to claim 8, characterized in that, The developing component (170) is arranged on the side close to the expansion adjustment component (121).

10. The aspiration catheter for aspirating eccentric thrombi according to any one of claims 1-7, characterized in that, The suction port (111) has an arc-shaped chamfer at the edge of its end face.

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