A high-efficiency sterilization fermentation integrated device for peptide-rich biological raw materials

Abstract

The application discloses a kind of for rich peptide biological raw material high-efficiency sterilization fermentation integrated device, belong to biological fermentation technical field, the device includes fermentation tank, support leg, drive assembly, stirring shaft, stirring rod, base assembly and air support mechanism, by being provided with the base assembly of annular air chamber and top orifice plate by setting in the inside bottom of fermentation tank, stirring shaft passes through the through hole in the center of annular air chamber and retains annular gap between two, the sterilization gas that air support mechanism sprays upward is evenly flowed from the gap after being distributed by top orifice plate, and is adhered to the outer wall of stirring shaft and moves upward, forms the continuous annular air film around the shaft, the gas isolation layer of one-way flow from inside to outside is established on the surface of stirring shaft by positive pressure, fundamentally prevents the penetration and stagnation of fermentation broth to the gap between shaft and base cooperation.

Description

Technical Field

[0001] This invention belongs to the field of bio-fermentation technology, specifically, it relates to an integrated device for efficient sterilization and fermentation of peptide-rich bio-raw materials. Background Technology

[0002] Peptide-rich bio-raw materials, such as fermented soybean meal, fish lysate peptides, and yeast hydrolysates, are functional raw materials rich in small molecule peptides and amino acids, which are transformed from animal and plant proteins through microbial fermentation. They are widely used in feed, fertilizers, and health foods. The production of these raw materials highly depends on pure-culture fermentation technology, which must be carried out in a strictly sterile environment to ensure the quality, safety, and functional activity of the products.

[0003] In the field of fermentation equipment, mechanically stirred and aerated fermenters are the most commonly used devices. To achieve pure culture, existing technologies are mainly designed in the following three aspects: (a) Sterilization of culture medium Sterilization is usually carried out in batches or continuously, using steam to heat the culture medium to 121°C and maintain it for a certain period of time to kill all microorganisms and their spores.

[0004] (II) Preparation of sterile air The air required for aerobic fermentation needs to be compressed, cooled, and degreased and dehydrated before being filtered and sterilized through a microporous membrane filter made of materials such as polytetrafluoroethylene (PTFE) before being introduced into the fermentation tank.

[0005] (iii) Online sterilization of tanks and pipelines Empty tanks and all connected pipes and valves must be heated to 121°C with pure steam and kept at that temperature and pressure to kill all live bacteria on the inner walls of the equipment.

[0006] For example, the invention patent with announcement number CN113604330A discloses a biological raw material fermentation device, including a fermentation tank. The bottom of the fermentation tank is equipped with support legs, and the top of the fermentation tank is equipped with a sealing cover. A stirring motor is installed on the top of the sealing cover, and a stirring frame is installed at the bottom of the sealing cover. The rotating shaft of the stirring frame passes through the sealing cover and is connected to the stirring motor. A discharge port is provided on one side of the fermentation tank. The fermentation tank is equipped with a stirring device and a cleaning device, which achieves the purpose of improving structural stability and can prevent the stirring structure from loosening after long-term use, thereby improving the safety of biomass raw material fermentation. When the internal parts of the fermentation tank are corroded during the fermentation process, causing the biomass raw material to deteriorate, an alarm can be triggered, effectively preventing the use of deteriorated biomass raw material fermentation products and improving the cleaning effect of the fermentation tank.

[0007] However, the stirring shaft of a fermenter usually runs through the center of the bottom of the tank. To ensure the stable rotation of the shaft, a bearing or bushing is usually installed at the bottom. However, the gap between the bearing and the shaft becomes a permanent dead corner that cannot be thoroughly cleaned and sterilized when the material is immersed in a high-viscosity liquid rich in protein and peptides for a long time. After the liquid seeps into this gap, it will accumulate due to denaturation and scaling, becoming a breeding ground for bacteria. This results in a very high risk of batch-to-batch contamination and is difficult to clean. Summary of the Invention

[0008] The purpose of this section is to outline some aspects of embodiments of the present invention and to briefly describe some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be construed as limiting the scope of the invention.

[0009] To address the issue raised in the background section that the stirring shaft of a fermenter typically runs through the center of the tank bottom, and that bearings or bushings are usually installed at the bottom to ensure stable rotation of the shaft, the clearance between the bearing and the shaft becomes a permanent dead zone that is physically impossible to thoroughly clean and sterilize when the material is immersed in a high-viscosity liquid rich in proteins and peptides for a long time. After the liquid seeps into this gap, it will accumulate due to denaturation and scaling, becoming a breeding ground for miscellaneous bacteria, resulting in a very high risk of batch-to-batch contamination and making it difficult to clean. The present invention adopts the following technical solution.

[0010] An integrated device for efficient sterilization and fermentation of peptide-rich biological raw materials includes a fermenter. Multiple support legs are fixedly connected to the four corners of the fermenter's bottom. A drive assembly is detachably connected to the upper end of the fermenter. The rotating end of the drive assembly is inserted into the fermenter and detachably connected to a stirring shaft. Multiple stirring rods are detachably connected to the stirring shaft, and a conical head is provided at the insertion end of the stirring shaft. A base assembly is installed at the bottom of the fermenter. An air support mechanism is provided on the inner bottom of the base assembly. The base assembly is inserted into the air support mechanism, which sprays sterilization gas upwards. The gas flows out from the gap between the base assembly and the stirring shaft and moves upwards along the stirring shaft. The base assembly includes an annular air chamber and a top perforated plate. The annular air chamber is detachably connected to the center of the inner bottom of the fermenter, and the top perforated plate is detachably connected to the upper end of the annular air chamber. A through hole is provided at the center of the annular air chamber, through which the stirring shaft passes, and a gap exists between the stirring shaft and the through hole.

[0011] Preferably, a protective mechanism is installed on the outside of the base assembly, which seals the base assembly when the gas supply to the inside of the fermenter is cut off.

[0012] Preferably, the air support mechanism includes a top-opening nozzle, a partition plate is fixedly connected inside the annular air chamber, the top-opening nozzle is detachably connected to the upper end of the partition plate, the top-opening nozzle blows sterilizing gas toward the top perforated plate, the top-opening nozzle is connected to an external air supply component, the air supply component sprays the sterilizing gas upward through the top-opening nozzle, and then distributes it through the top perforated plate, forming a uniform, high-speed jet on the outer wall of the stirring shaft, shaping the airflow into an annular air film of uniform thickness around the shaft.

[0013] Preferably, a side-opening nozzle is detachably connected to the bottom inner side of the annular air chamber. The side-opening nozzle is connected to an external air supply assembly. Multiple lateral jet holes are provided on the outer wall of the annular air chamber near the bottom. During stirring, the side-opening nozzle and the top-opening nozzle spray air simultaneously. During cleaning, the top-opening nozzle reduces the amount of air sprayed. During cleaning, the air supply of the top-opening nozzle is reduced, and high-pressure pulsed airflow is only introduced into the lateral jet holes to create intense gas-liquid two-phase turbulence in the annular space between the shaft and the air chamber. This provides high-intensity pulsed scouring to the outer surface of the stirring shaft and the inner wall of the base assembly. At this time, the upper air chamber only maintains a small amount of positive pressure protection to prevent the cleaning liquid from flowing back into the upper fine channels.

[0014] Preferably, an air supply mechanism is installed at the bottom of the fermenter, which is connected to the side opening nozzle and the top opening nozzle respectively, so that the side opening nozzle and the top opening nozzle are supplied with air independently.

[0015] Preferably, the gas supply mechanism includes an air intake main pipe, a connecting sleeve, a first branch pipe, and a second branch pipe. The first branch pipe is connected and communicates with the side-opening nozzle. The second branch pipe passes through the side-opening nozzle and the partition plate and is connected and communicates with the top-opening nozzle. The connecting sleeve is fitted on the outer wall of the first branch pipe and the second branch pipe. The air intake main pipe is fixedly connected to the bottom of the connecting sleeve. The first branch pipe bends and extends from the air intake main pipe to one side, and the second branch pipe bends and extends from the air intake main pipe to the other side.

[0016] Preferably, the protection mechanism includes an outer wall protection plate, connecting rods, and a second conical block. The upper end of the top perforated plate is provided with an inner conical surface. The outer wall protection plate is sleeved on the outer wall of the base assembly. The connecting rods are symmetrically fixedly connected to the upper two sides of the outer wall protection plate. The tip of the second conical block is set downward and fixedly connected to the connecting rods on both sides. When the side opening nozzle and the top opening nozzle spray air, the top opening nozzle blows up and blows the second conical block upward. When the external air supply is abnormally cut off, the outer wall protection plate and the second conical block fall down by gravity.

[0017] Preferably, a first conical block with its tip pointing upwards is fixedly connected to the outer wall of the stirring shaft above the top perforated plate, and a second conical block is attached to the first conical block to form a cone with tips at both the top and bottom, which guides the airflow.

[0018] Preferably, the outer wall of the outer protective panel is provided with an inclined surface.

[0019] Preferably, the two ends of the intake manifold are connected to intake check valves, and the two intake check valves are connected to the air supply assembly.

[0020] Compared with the prior art, the beneficial effects of the present invention are as follows: 1. In this invention, a base assembly consisting of an annular air chamber and a top perforated plate is provided at the bottom of the inner side of the fermenter. The stirring shaft passes through the through hole in the center of the annular air chamber with an annular gap between them. The sterilizing gas sprayed upward by the air support mechanism is distributed by the top perforated plate and flows out evenly from the gap. It then moves upward along the outer wall of the stirring shaft to form a continuous annular air film around the shaft. This air film establishes a positive pressure gas isolation layer that flows unidirectionally from the inside to the outside on the surface of the stirring shaft. This fundamentally prevents the fermentation liquid from penetrating and stagnating into the gap between the shaft and the base, completely eliminating the physical dead zone that becomes a breeding ground for miscellaneous bacteria due to the accumulation and denaturation of the liquid. This ensures the long-term maintenance of a high-cleanliness fermentation environment.

[0021] 2. In this invention, when the external gas supply is abnormally interrupted, the second conical block and the outer wall protection plate of the protection mechanism automatically descend under their own weight after losing the airflow support. The conical surface of the second conical block forms a tight fit with the inner conical surface of the top perforated plate or the first conical block on the stirring shaft, sealing the gas flow channel of the base assembly. This effectively prevents the fermentation liquid from flowing back into the gas chamber and the upper fine channel during the gas supply interruption, ensuring the reliability and recoverability of the system under unexpected working conditions.

[0022] 3. In this invention, the two ends of the main air inlet pipe of the air supply mechanism are connected to independent air supply components through one-way air inlet valves. The first branch pipe supplies air to the side-opening nozzle, and the second branch pipe passes through the partition plate to supply air to the top-opening nozzle. The connecting sleeve encapsulates the two branch pipes together, realizing independent air supply for the side-opening nozzle and the top-opening nozzle. This allows the generation of the annular gas film during normal fermentation and the pulse flushing during the cleaning mode to be controlled independently without interference, thus improving the flexibility and reliability of the system operation. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the structure of an integrated device for efficient sterilization and fermentation of peptide-rich biological raw materials according to the present invention. Figure 2 This is a front view structural diagram of the integrated device for efficient sterilization and fermentation of peptide-rich biological raw materials in this invention. Figure 3 This is a schematic diagram of the base assembly structure in this invention; Figure 4 This is a cross-sectional view of the base assembly in this invention; Figure 5 This is a schematic diagram of the gas attitude in this invention; Figure 6 This is a schematic diagram of the protective mechanism structure in this invention; Figure 7 This is a cross-sectional view of the protective mechanism in this invention; Figure 8 This is a schematic diagram of the gas supply mechanism in this invention.

[0024] The correspondence between the labels and component names in the attached figures is as follows: 100. Fermentation tank; 101. Support leg; 102. Drive assembly; 103. Stirring shaft; 104. Stirring rod; 105. Conical head; 106. First conical block; 200. Base assembly; 201. Annular air chamber; 202. Side air jet; 203. Top perforated plate; 204. Partition plate; 205. Inner conical surface; 300. Air support mechanism; 301. Side-opening nozzle; 302. Top-opening nozzle; 400. Protective mechanism; 401. Outer wall protective plate; 402. Inclined surface; 403. Connecting rod; 404. Second conical block; 500, Gas supply mechanism; 501, Main air inlet pipe; 502, Air inlet check valve; 503, Connecting pipe sleeve; 504, First branch pipe; 505, Second branch pipe. Detailed Implementation

[0025] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0026] Many specific details are set forth in the following description in order to provide a full understanding of the invention. However, the invention may also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the invention. Therefore, the invention is not limited to the specific embodiments disclosed below.

[0027] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places throughout this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that mutually excludes other embodiments. The present invention provides the following embodiments.

[0028] like Figure 1 , Figure 2 , Figure 3 as well as Figure 4The diagram shows a preferred embodiment of the present invention of an integrated device for efficient sterilization and fermentation of peptide-rich biological raw materials. This embodiment includes a fermentation tank 100. Multiple support legs 101 are fixedly connected to the four corners of the bottom of the fermentation tank 100. A drive assembly 102 is detachably connected to the upper end of the fermentation tank 100. The rotating end of the drive assembly 102 is inserted into the interior of the fermentation tank 100 and detachably connected to a stirring shaft 103. Multiple stirring rods 104 are detachably connected to the stirring shaft 103. A base assembly 200 is installed at the bottom of the fermentation tank 100. An air support mechanism 300 is provided on the inner bottom of the base assembly 200. The base assembly 200 is inserted into the air support mechanism 300. The air support mechanism 300 sprays sterilization gas upwards. The gas flows out from the gap between the base assembly 200 and the stirring shaft 103 and moves upwards along the stirring shaft 103. A conical head 105 is provided at the insertion end of the stirring shaft 103. In this embodiment, the stirring shaft 104... The 03 connector does not contact the bottom of the fermenter 100. In conjunction with the sterilizing gas blown out by the air support mechanism 300, the hydrodynamic pressure effect generated when the gas passes through the narrow annular gap between the stirring shaft 103 and the base assembly 200 at high speed forms a high-pressure gas film that tightly wraps the shaft wall and is uniform and continuous. This high-pressure gas film acts as a dynamic barrier, completely isolating the fermentation liquid from the critical gap. According to the principle of extrusion film in fluid mechanics, when the stirring shaft 103 attempts to deviate to one side due to rotational oscillation or liquid impact, the gap on that side decreases sharply, the gas in the gap is instantly compressed, and the pressure increases nonlinearly. Meanwhile, the gap on the opposite side increases, and the pressure drops rapidly. The huge radial pressure difference generated in this instant creates a strong restoring force, which automatically pushes the stirring shaft 103 back and locks it at the geometric center of the gas chamber center hole. Thus, without introducing any mechanical contact or wear, it provides continuous, stable, and high-rigidity radial straightening support for the bottom of the long stirring shaft 103, completely replacing the traditional sliding bearing that is prone to bacterial contamination.

[0029] The specific structure of the base assembly 200 can be as follows: Figure 3 , Figure 4 as well as Figure 5In the embodiment shown, the base assembly 200 includes an annular air chamber 201 and a top perforated plate 203. The annular air chamber 201 is detachably connected to the center of the bottom inner side of the fermenter 100, and the top perforated plate 203 is detachably connected to the upper end of the annular air chamber 201. A through hole is provided at the center of the annular air chamber 201, through which the stirring shaft 103 passes, and there is a gap between the stirring shaft 103 and the through hole. In this embodiment, by setting the top perforated plate 203, the sterilizing gas sprayed by the air support mechanism 300 is precisely distributed by the top perforated plate 203 and rises vertically upwards in a uniform and high-speed jet form, closely adhering to the outer wall of the stirring shaft 103. This shapes the airflow into an annular air film of uniform thickness around the shaft, eliminating the local weak points of the free jet and ensuring 360-degree sweeping and isolation of the liquid climbing along the shaft.

[0030] The specific structure of the gas support mechanism 300 can be as follows: Figure 4 In the embodiment shown, the air support mechanism 300 includes a top-opening nozzle 302. A partition plate 204 is fixedly connected inside the annular air chamber 201. The top-opening nozzle 302 is detachably connected to the upper end of the partition plate 204. The top-opening nozzle 302 blows sterilizing gas toward the top perforated plate 203. The top-opening nozzle 302 is connected to an external air supply component. In this embodiment, the external air supply component is connected to the top-opening nozzle 302. The air supply component sprays the sterilizing gas upward through the top-opening nozzle 302 and then distributes it through the top perforated plate 203 to form a uniform, high-speed jet on the outer wall of the stirring shaft 103, shaping the airflow into an annular air film of uniform thickness around the shaft.

[0031] After prolonged use, the fermenter 100 requires cleaning of its inner wall and the stirring shaft 103. To improve the cleaning effect, the specific structure can be as follows: Figure 4In the embodiment shown, a side-opening nozzle 301 is detachably connected to the inner bottom of the annular gas chamber 201. The side-opening nozzle 301 is connected to an external gas supply assembly. Multiple lateral jet holes 202 are provided on the outer wall of the annular gas chamber 201 near the bottom. During stirring, the side-opening nozzle 301 and the top-opening nozzle 302 simultaneously release gas. During cleaning, the top-opening nozzle 302 reduces its gas release. In this embodiment, during normal fermentation, the side-opening nozzle 301 and the top-opening nozzle 302 simultaneously release gas. The gas ejected from the top-opening nozzle 302 forms a vertical air curtain along the stirring shaft 103, responsible for axial dynamic sealing and pneumatic alignment. The ejected gas forms a downward rotating spiral air curtain in the annular gap between the stirring shaft 103 and the inner wall of the annular air chamber 201, which is responsible for radial isolation and preventing foam from rising. The two airflow directions are orthogonal, forming a three-dimensional composite sterile barrier. During cleaning, the air supply of the top opening nozzle 302 can be reduced, and high-pressure pulse airflow is only introduced into the side jet hole 202. This creates a violent gas-liquid two-phase turbulence in the annular space between the shaft and the air chamber, which performs high-intensity pulsed scouring on the outer surface of the stirring shaft 103 and the inner wall of the base assembly 200. At this time, the upper air chamber only maintains a small amount of positive pressure protection to prevent the cleaning liquid from flowing back into the upper fine channel.

[0032] During the mixing process, if the external air supply is abnormally cut off, the internal liquid will enter the base assembly 200, causing blockage of the side air jet 202, side opening nozzle 301, and top opening nozzle 302, which is difficult to clean. To prevent the liquid from entering the base assembly 200 after the air supply is abnormally cut off, the specific structure can be as follows: Figure 6 as well as Figure 7In the embodiment shown, a protective mechanism 400 is installed on the outside of the base assembly 200. The protective mechanism 400 closes the base assembly 200 when the gas supply to the interior of the fermenter 100 is cut off. The protective mechanism 400 includes an outer wall protective plate 401, a connecting rod 403, and a second conical block 404. The upper end of the top perforated plate 203 is provided with an inner conical surface 205. The outer wall protective plate 401 is sleeved on the outer wall of the base assembly 200. The outer wall of the outer wall protective plate 401 is provided with an inclined surface 402. The connecting rod 403 is symmetrically fixedly connected to the upper two sides of the outer wall protective plate 401. The stirring shaft 103 is located above the top perforated plate 203 and the outer wall is fixedly connected to a first conical block 106 with its tip pointing upwards. The second conical block 404 is provided with its tip pointing downwards and is fixedly connected to the connecting rods 403 on both sides. In this embodiment, on the side... When the open nozzle 301 and the top open nozzle 302 spray air, the top open nozzle 302 blows up the second conical block 404, which in turn causes the outer wall protection plate 401 to move upward through the connecting rods 403 on both sides, exposing the side air jet hole 202 and the top perforated plate 203, allowing the gas to be sprayed outward. The setting of the first conical block 106 allows the second conical block 404 to fit with the first conical block 106 to form a cone with pointed ends at both ends, which can guide the airflow. When the external air supply is abnormally cut off, the outer wall protection plate 401 and the second conical block 404 fall down by gravity, blocking the side air jet hole 202 and the top perforated plate 203, preventing the liquid from entering the interior of the base assembly 200. The setting of the inclined surface 402 reduces the resistance when the outer wall protection plate 401 falls.

[0033] In order to independently control the jet flow of the side-opening nozzle 301 and the top-opening nozzle 302, the specific structure can be as follows: Figure 8In the embodiment shown, a gas supply mechanism 500 is installed at the bottom of the fermenter 100. The gas supply mechanism 500 is connected to the side-opening nozzle 301 and the top-opening nozzle 302 respectively, so that the side-opening nozzle 301 and the top-opening nozzle 302 are supplied with gas independently. The gas supply mechanism 500 includes an air inlet main pipe 501, a connecting sleeve 503, a first branch pipe 504, and a second branch pipe 505. The first branch pipe 504 is connected to and communicates with the side-opening nozzle 301, and the second branch pipe 505 passes through the side-opening nozzle 301 and the partition plate 204 and is connected to and communicates with the top-opening nozzle 302. The connecting sleeve 503 is fitted on the outer wall of the first branch pipe 504 and the second branch pipe 505. The main air intake pipe 501 is fixedly connected to the bottom of the connecting sleeve 503. The first branch pipe 504 bends and extends from the main air intake pipe 501 to one side, and the second branch pipe 505 bends and extends from the main air intake pipe 501 to the other side. The two ends of the main air intake pipe 501 are respectively connected to the one-way valve 502. The one-way valves 502 on both sides are respectively connected to the air supply components. In this embodiment, through independent air supply pipes, the air supply components on both sides supply air to the side opening nozzle 301 and the top opening nozzle 302, respectively. Thus, the air supply intensity of the side opening nozzle 301 and the top opening nozzle 302 can be controlled independently, thereby adapting to the air supply intensity requirements of different scenarios such as fermentation and cleaning.

[0034] The above description, in conjunction with specific embodiments, provides a further detailed explanation of the present invention. It should not be construed that the specific implementation of the present invention is limited to these descriptions. For those skilled in the art, several simple deductions or substitutions can be made without departing from the concept of the present invention, and all such deductions or substitutions should be considered to fall within the scope of protection defined by the claims submitted herein.

Claims

1. An integrated device for efficient sterilization and fermentation of peptide-rich biological raw materials, comprising a fermenter (100), wherein multiple support legs (101) are fixedly connected to the four corners of the bottom of the fermenter (100), a drive assembly (102) is detachably connected to the upper end of the fermenter (100), the rotating end of the drive assembly (102) is inserted into the interior of the fermenter (100) and is detachably connected to a stirring shaft (103), and multiple stirring rods (104) are detachably connected to the stirring shaft (103), characterized in that, The insertion end of the stirring shaft (103) is provided with a conical head (105). A base assembly (200) is installed at the bottom of the fermenter (100). An air support mechanism (300) is provided on the inner bottom of the base assembly (200). The base assembly (200) is inserted into the air support mechanism (300). The air support mechanism (300) sprays sterilizing gas upward. The gas flows out from the gap between the base assembly (200) and the stirring shaft (103) and adheres to the stirring shaft (105). 03) Moving upward, the base assembly (200) includes an annular air chamber (201) and a top perforated plate (203). The annular air chamber (201) is detachably connected to the center of the bottom of the inner side of the fermenter (100). The top perforated plate (203) is detachably connected to the upper end of the annular air chamber (201). A through hole is provided at the center of the annular air chamber (201). The stirring shaft (103) passes through the through hole, and there is a gap between the stirring shaft (103) and the through hole.

2. The integrated device for high-efficiency sterilization and fermentation of peptide-rich biological raw materials according to claim 1, characterized in that, The base assembly (200) is externally fitted with a protective mechanism (400) that closes the base assembly (200) when the gas supply to the interior of the fermenter (100) is cut off.

3. The integrated device for high-efficiency sterilization and fermentation of peptide-rich biological raw materials according to claim 1, characterized in that, The air support mechanism (300) includes a top-opening nozzle (302). A partition plate (204) is fixedly connected inside the annular air chamber (201). The top-opening nozzle (302) is detachably connected to the upper end of the partition plate (204). The top-opening nozzle (302) blows sterilizing gas toward the top perforated plate (203). The top-opening nozzle (302) is connected to an external air supply component. The air supply component sprays the sterilizing gas upward through the top-opening nozzle (302) and then distributes it through the top perforated plate (203) to form a uniform, high-speed jet on the outer wall of the stirring shaft (103), shaping the airflow into an annular air film of uniform thickness around the shaft.

4. The integrated device for high-efficiency sterilization and fermentation of peptide-rich biological raw materials according to claim 3, characterized in that, A side-opening nozzle (301) is detachably connected to the bottom inner side of the annular air chamber (201). The side-opening nozzle (301) is connected to an external air supply assembly. Multiple side-jet holes (202) are provided on the outer wall of the annular air chamber (201) near the bottom. During stirring, the side-opening nozzle (301) and the top-opening nozzle (302) spray air simultaneously. During cleaning, the top-opening nozzle (302) reduces the amount of air sprayed. During cleaning, the air supply of the top-opening nozzle (302) is reduced, and high-pressure pulse airflow is only introduced into the side-jet holes (202). This creates intense gas-liquid two-phase turbulence in the annular space between the shaft and the air chamber, and performs high-intensity pulsed scouring on the outer surface of the stirring shaft (103) and the inner wall of the base assembly (200). At this time, the upper air chamber only maintains a small amount of positive pressure protection to prevent the cleaning liquid from flowing back into the upper fine channel.

5. The integrated device for efficient sterilization and fermentation of peptide-rich biological raw materials according to claim 4, characterized in that, A gas supply mechanism (500) is installed at the bottom of the fermenter (100). The gas supply mechanism (500) is connected to the side opening nozzle (301) and the top opening nozzle (302) respectively, so that the side opening nozzle (301) and the top opening nozzle (302) are supplied with gas separately.

6. The integrated device for high-efficiency sterilization and fermentation of peptide-rich biological raw materials according to claim 5, characterized in that, The gas supply mechanism (500) includes an intake manifold (501), a connecting sleeve (503), a first branch pipe (504), and a second branch pipe (505). The first branch pipe (504) is connected to and communicates with the side-opening nozzle (301). The second branch pipe (505) passes through the side-opening nozzle (301) and the partition plate (204) and is connected to and communicates with the top-opening nozzle (302). The connecting sleeve (503) is fitted on the outer wall of the first branch pipe (504) and the second branch pipe (505). The intake manifold (501) is fixedly connected to the bottom of the connecting sleeve (503). The first branch pipe (504) bends and extends from the intake manifold (501) to one side, and the second branch pipe (505) bends and extends from the intake manifold (501) to the other side.

7. The integrated device for efficient sterilization and fermentation of peptide-rich biological raw materials according to claim 6, characterized in that, The protection mechanism (400) includes an outer wall protection plate (401), a connecting rod (403), and a second conical block (404). The upper end of the top perforated plate (203) is provided with an inner conical surface (205). The outer wall protection plate (401) is sleeved on the outer wall of the base assembly (200). The connecting rod (403) is symmetrically fixedly connected to the upper two sides of the outer wall protection plate (401). The tip of the second conical block (404) is set downward and fixedly connected to the connecting rods (403) on both sides. When the side opening nozzle (301) and the top opening nozzle (302) spray air, the top opening nozzle (302) blows up and blows the second conical block (404) upward. When the external air supply is abnormally cut off, the outer wall protection plate (401) and the second conical block (404) fall down by gravity.

8. The integrated device for high-efficiency sterilization and fermentation of peptide-rich biological raw materials according to claim 7, characterized in that, The stirring shaft (103) is fixedly connected to the outer wall above the top perforated plate (203) with a first conical block (106) pointing upwards. The second conical block (404) fits into the first conical block (106) to form a cone with pointed ends at both ends, which guides the airflow.

9. The integrated device for high-efficiency sterilization and fermentation of peptide-rich biological raw materials according to claim 7, characterized in that, The outer wall of the outer protective plate (401) is provided with an inclined surface (402).

10. The integrated device for efficient sterilization and fermentation of peptide-rich biological raw materials according to claim 6, characterized in that, The two ends of the intake manifold (501) are connected to intake check valves (502), and the two intake check valves (502) on both sides are connected to the air supply assembly.

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