Fluid delivery device supporting replacement of a cartridge in a cannulated installed state

Abstract

A system and method for replacing a fluid cartridge of a fluid delivery device is provided. The system includes a fluid delivery device for expelling fluid from a fluid cartridge. The device includes a reusable unit and a disposable unit. The system further includes a cartridge adapter configured to facilitate a first connection between the reusable unit and the disposable unit and additionally to facilitate an alternative connection between the reusable unit and a priming chamber to prime a replacement fluid cartridge.

Description

Technical Field

[0001] This invention relates generally to the field of fluid delivery devices, and more particularly to wearable drug delivery systems. Background Technology

[0002] Many drug delivery devices include a cannula inserted into the user's body through which the drug is delivered from the device's cylinder. Some of these devices are worn on the user's belt, with tubing extending from the cylinder to the cannula; others are attached directly to the user's skin, with the cannula extending directly into the patient's body from the device's cylinder.

[0003] Typically, once the fluid cartridge of such a device is depleted, the device must be removed from the patient's body to replace the cartridge. The cannula is often removed along with it, especially if the operator lacks specialized medical training. However, by increasing the cartridge volume or by allowing the cartridge to be replaced while the cannula is in place, the cannula can usually remain safely in position for a longer period. Summary of the Invention

[0004] This invention and its embodiments provide a system and method for fluid delivery via injection from a wearable device, particularly for the delivery of medication to a patient. The wearable device is typically attached to the patient's body surface and includes a disposable unit and a reusable unit. The disposable unit contains a triggerable cannula for insertion into the patient's body, and the reusable unit includes a drive mechanism for driving fluid flow from a fluid cartridge through the cannula. The reusable unit may include a motor for driving the drive mechanism and a processor for controlling the movement of the motor, particularly the movement of discharging fluid.

[0005] The system includes a component that allows for the replacement of the fluid cartridge while the cannula remains inside the user's body, thereby avoiding unnecessary cannula removal and insertion steps. Attached Figure Description

[0006] To better understand the various embodiments of the present invention and illustrate how they achieve their effects, examples are now provided in conjunction with the accompanying drawings. The drawings illustrate structural details of the invention to provide a basic understanding of the invention. Combined with the description, those skilled in the art can clearly understand how various forms of the invention can be implemented.

[0007] In the attached image:

[0008] Figures 1A to 1B A schematic diagram of the components of a system for fluid transport is shown; according to some embodiments of the present invention, Figure 1A The diagram shows reusable components, fluid cartridges, cartridge adapters, disposable components, and filling chambers. Figure 1BThe fluid delivery device assembling the system is shown;

[0009] Figures 2A to 2B A schematic diagram of both sides of the cylindrical adapter is shown;

[0010] Figures 3A to 3D A schematic diagram of a fluid cylinder with an attached cylinder adapter is shown;

[0011] Figures 4A to 4C A schematic diagram of a reusable component of a fluid delivery device is shown; Figure 4A Individual reusable units are shown. Figure 4B A fluid cylinder with a reusable component inserted is shown. Figure 4C A fluid cylinder with an attached cylinder adapter and a reusable insert is shown.

[0012] Figures 5A to 5B A schematic diagram of the infusion cavity is shown, including isometric views ( Figure 5A ) and side sectional view ( Figure 5B );

[0013] Figures 6A to 6B A flowchart is shown showing the process of replacing the fluid cylinder of the fluid delivery device, with each step accompanied by a diagram and corresponding text description. Detailed Implementation

[0014] It should be understood that the present invention and its applications are not limited to the systems and methods described below, nor to the component arrangements illustrated or shown in the accompanying drawings, but are applicable to other embodiments implemented or realized in various ways.

[0015] Figure 1A This is a schematic diagram of the various parts of a fluid delivery system 10, which are interconnected to form an operable fluid delivery device. The system typically includes a reusable component 20, a fluid cartridge 22 (with a cap end 24, also called a diaphragm), a cartridge adapter 26, a disposable component 28, and an infusion chamber 32. The disposable component may also be referred to as the "base" because, when the fluid delivery device is assembled, the reusable component is typically placed on top of the disposable component, which is then attached to a surface such as the patient's body. Since the disposable component includes a cannula for injecting fluid into the body, it must be replaced (disposal) after removal from the body surface to meet aseptic operation standards.

[0016] Figure 1B An assembled fluid delivery device 40 is shown, comprising a fluid cylinder and having a reusable component 20, a cylinder adapter 26, and a disposable component 28. The disposable component typically has an adhesive-based substrate 30 for attaching the assembled device to a patient's body (or other object surface).

[0017] A typical application of System 10 is as a wearable device for automated drug delivery, such as an insulin pump. A fluid delivery device housing a fluid cylinder is described in the international patent publication, text WO2021 / 099992A2, by the inventor of this application, Ben David. The reusable component of the fluid delivery device typically includes a drive mechanism having a central longitudinal axis arranged to move forward in the axial direction to compress the plunger of the fluid cylinder, thereby expelling fluid from the cap end of the cylinder. The reusable component also typically includes a controller (i.e., a computer processor) for controlling the rate and frequency of fluid expulsion. The controller may receive signals from a user device (such as a mobile device) to determine the amount of fluid to be expelled, or the planned injection dose and frequency. The controller signals the drive mechanism to expel the planned amount, actuating the mechanism in appropriate increments. The controller may also send signals to the drive mechanism to perform infusion, as described below. The drive mechanism may have a bidirectional motor with a motor shaft rotatable in a first and a second direction. The reusable unit may also include a battery that powers the controller and motor, and the battery may be rechargeable.

[0018] The disposable unit has a cannula for conveying fluid flowing from the fluid cartridge, typically delivering the fluid to the patient's body. When the fluid delivery device is assembled and attached to a surface such as the patient's body, the drive mechanism of the reusable component discharges fluid according to a configurable schedule, the fluid flowing through the cannula of the disposable component. As the device is moved to different locations on the patient's body, the disposable component is typically replaced with a new, sterile disposable component (along with its associated cannula), while the reusable component, which does not come into direct contact with the discharged fluid, can be reused.

[0019] Safe operation of fluid delivery devices requires initial perfusion of the fluid cartridge and cannula before insertion into the patient. Initial perfusion involves draining fluid through the cannula. Subsequently, for fluid cartridge replacement with the cannula already in place, the replacement cartridge must also be "perfused," meaning the plunger of the replacement cartridge must be moved to ensure fluid fills the full volume of the cartridge and that the initial plunger friction is overcome. By overcoming this initial friction, perfusion of the replacement cartridge ensures that there is no under- or over-dispensing of fluid into the cannula.

[0020] Another important reason for perfusing the replacement cartridge is to ensure proper attachment of the reusable unit to the cartridge, allowing the drive mechanism to firmly press against the cartridge plunger. The reusable unit is positioned to slightly push the cartridge plunger when attached. The plunger cannot move forward until the needle in the perfusing chamber punctures the diaphragm in the fluid cartridge, allowing insulin to flow out and thus perfuse the cartridge. This perfusing method ensures correct positioning of the reusable unit and cartridge plunger, avoiding gaps or preload that could lead to under- or over-dispensing. Perfusing is typically performed automatically after attachment, without requiring manual triggering by the user.

[0021] Figures 2A to 2B A schematic diagram showing both sides of the frame 42 of the cylindrical adapter 26 is shown. One side ( Figure 2A Side 46) is connected to the reusable unit; and the other side (side 44) is configured to be connected to the disposable unit, or (alternatively) to the infusion chamber, as will be further explained below.

[0022] The cartridge adapter typically has a seal 50 into which the fluid cartridge is inserted, preventing fluid from seeping into the reusable component. The adapter also typically has one or more sensor / actuator contacts 52 on each side; one contact aligns with one or more contacts on the reusable unit, while the other contact aligns with contacts on either the disposable unit or the filling chamber. The sensor contacts allow the reusable unit to detect whether the cartridge adapter and filling chamber assembly is in place to perform filling; they also detect whether the cartridge adapter and disposable unit assembly is in place for routine fluid delivery operations. Typically, the controller within the reusable unit is configured to allow fluid output from the fluid cartridge only after the aforementioned connection is detected. The detection of the connection status can be achieved using various methods known in the art. For example, the contacts on the adapter can provide a conductive path to a resistive circuit within the disposable unit, and the adapter itself also has a parallel resistor. Therefore, when the reusable unit applies voltage to the adapter contacts, only assembling the adapter will generate a first current value; after the disposable unit is reassembled into the adapter, a second current value will be generated. The injection chamber can be equipped with similar resistor circuits of different resistance values, thereby distinguishing whether the detection indicates the injection chamber is properly assembled or the disposable unit is properly assembled.

[0023] The same contacts on the adapter can also be used to transmit activation signals to the disposable unit, such as signals to activate cannula insertion. For example, the insertion actuator in the disposable unit can be implemented using a nitinol wire with shape memory properties that can be activated by current. A lower current intensity can be used to detect the presence of attachment between the disposable unit and the infusion chamber, while a higher current intensity can activate the nitinol wire, switching it to its activation configuration, which is preset for cannula insertion.

[0024] To facilitate the connection of the cartridge adapter to the reusable unit, the disposable unit, and the filling chamber, these connecting parts typically have connection points, such as magnets 54, that interconnect with each other. Additional connection points may be, for example, recessed channels 56 that can engage with corresponding ridge tracks on the disposable unit and the filling chamber, as described below.

[0025] The cartridge adapter also includes a clip 60 to prevent the cartridge adapter from being removed from the fluid cartridge after attachment. This forces the user to use a new cartridge adapter and thus encourages the use of a filling chamber for replacing the fluid cartridge, as described further below.

[0026] Figures 3A to 3D A multi-angle schematic diagram of a fluid cartridge 22 with an attached cartridge adapter 26 is shown. The fluid cartridge cap 24 (i.e., the "diaphragm end") and the connection point 54 of the cartridge adapter described above are also shown. A clip 60 of the cartridge adapter is also shown, which prevents the fluid cartridge from being removed after it has been installed in place, thus guiding the user to use a new cartridge adapter when replacing a fluid cartridge used with a disposable unit.

[0027] Figures 4A to 4B A schematic diagram of a reusable component 20 of a fluid delivery device is shown, including a connection point 54 (e.g., a magnet). Figure 4A A reusable component without a fluid cylinder is shown. A sleeve 62 of the reusable unit is shown, into which the fluid cylinder can be inserted. A sensor 64 positioned on the reusable unit is also shown for sensing the presence of the cylinder adapter (typically aligned with sensor contacts on the cylinder adapter).

[0028] Figure 4B A fluid cylinder 22 with a reusable component inserted is shown.

[0029] Figure 4C A fluid cylinder 22 is shown, into which a reusable unit is inserted and to which a cylinder adapter 26 is attached. As shown, the diaphragm end 24 of the cylinder typically protrudes from the adapter for insertion of disposable components.

[0030] Figures 5A to 5BA schematic diagram of the infusion chamber 32 is shown, along with an isometric view of the infusion chamber facing the fluid cartridge and a side sectional view. Both figures show the needle 70 of the infusion chamber, which pierces the diaphragm of the fluid cartridge to allow fluid drainage. Fluid drainage perfuses the fluid cartridge, ensuring that subsequent movement of the fluid cartridge plunger drains a corresponding, measured amount of fluid. An infusion chamber is not required for perfusion of the initial fluid cartridge used with a disposable unit, as perfusion occurs when the initial fluid cartridge is attached to the disposable unit, and fluid is drained through a cannula before the disposable unit is attached to the patient's body.

[0031] Fluid discharged during infusion using the infusion chamber can be delivered to chamber 74 of the infusion chamber 32. To ensure aseptic use, a single infusion chamber is typically used only once for a single replacement fluid cartridge. The use of the infusion chamber is enforced by providing the infusion chamber along with a cartridge adapter as an "infusion unit." Since the cartridge adapter must be mounted on the fluid cartridge for use in the delivery system, the user attaches the replacement cartridge to the infusion chamber, thus simultaneously performing infusion and attaching the cartridge adapter to the fluid cartridge.

[0032] Figures 6A to 6B A schematic diagram of process 600 for replacing the initial fluid cylinder of a fluid delivery device when a disposable unit is attached to a patient is shown. Schematic diagrams of the device configuration at each step of the process are accompanied by textual descriptions of the steps.

[0033] The process begins at step 602, where the components are used to assemble a fluid delivery device for attachment to a patient. These components include: a reusable unit 20 (which may have been used in previous applications) and a disposable unit 28 (which needs to be new to ensure sterility of operation). A new fluid cartridge 22a (referred to herein as the “initial” fluid cartridge) is also provided. Furthermore, a new cartridge adapter 26a is provided, typically with the disposable unit, to facilitate user use and encourage adherence to the infusion protocol described herein.

[0034] In step 604, the user inserts the cartridge 22a into the reusable unit 20; and then, in step 606, the user inserts the reusable unit with the cartridge into the disposable unit 28 (“base”), assembling the components together so that the fluid delivery device 40a (i.e., the “pump”) is ready to be attached to and operated by the user. During component assembly, the cap end 24a of the cartridge engages with the cartridge adapter 26a, which is typically provided attached to the disposable unit.

[0035] As described above, the adapter includes a seal to prevent external fluids from seeping into the reusable unit. The adapter also includes a snap-fit ​​mechanism that engages at the rear of the cap, allowing the adapter to detach from the cartridge when it is removed from the disposable unit. Thus, the replacement cartridge can be fitted into the disposable unit only when a new adapter is attached to the replacement cartridge.

[0036] After the fluid delivery device 40a is assembled, infusion is completed before it is attached to the user. Specifically, the drive mechanism in the reusable unit is operated to expel a small amount of fluid from the cartridge, ensuring that no air is present in the cartridge or in the fluid path of the disposable unit's cannula before the device is adhered to the body. As described above, infusion can be performed automatically when a sensor indicates to the controller that the device is in the assembled state. Alternatively, infusion can be performed manually by user-triggered action, such as by operating a button on the device or by sending a remote signal (received by the reusable unit controller). Infusion can also be achieved without controller action by designing the reusable device such that the drive mechanism in the reusable device presses against a plunger inside the cartridge when the cartridge is inserted. Thus, when the device is assembled, not only does the needle (in the infusion chamber or disposable unit) pierce the cartridge diaphragm, but a force also exists on the plunger to expel a small amount of fluid. This infusion method can be referred to as "design-driven" infusion.

[0037] After infusion, the adhesive backing on the substrate of the disposable unit is typically removed. The adhesive facilitates bonding of the device to surfaces such as body surfaces.

[0038] The controller of the reusable unit can be configured to identify when the device adheres to a surface and initiate an operation that allows fluid to be delivered.

[0039] For long-term treatments such as insulin therapy, medical practice limits the duration the cannula can remain in the body. Therefore, when the time limit is reached, the device must be removed and the disposable unit replaced. However, if the cannula is empty (or must be replaced for other reasons) before the time limit expires, the disposable unit can remain in place for an extended period, requiring only the cannula to be replaced.

[0040] Step 608 shows the reusable unit 20 being detached from the disposable unit 28 while the disposable unit is still attached to the surface. Step 610 shows the fluid cylinder 22a being removed from the disposable unit along with the adapter 26a from the reusable unit.

[0041] It should be noted that if the battery power of the reusable unit is low, the user can (at step 608) replace the reusable unit 20 with another reusable unit with a charged battery and attach it to the cylinder and the disposable unit to reassemble the device 40a. Subsequently, the operation can continue (at step 606) until the cylinder is empty, at which point steps 608 and 610 can be repeated, and the process continues at step 612.

[0042] In step 612, the user inserts the replacement fluid cartridge 22b into the reusable unit 20; and then, in step 614, the user positions the filling chamber 32 to be attached to the reusable unit 20. The filling chamber can be provided with a new adapter 26b, which has the same structure as the first adapter 26a, facilitating the connection between the reusable unit and the filling chamber, as well as subsequent connections between the reusable unit and the disposable unit (or those required for such connections). A unit including a filling chamber with a pre-attached cartridge adapter can be referred to as a "filling unit".

[0043] In step 616, the user attaches the reusable unit 20 (with the replaceable fluid cylinder 22b) to the filling unit.

[0044] In step 616, when adapter 26b and filling chamber 32 are connected to the reusable unit 20 having fluid cartridge 22b, the needle within filling chamber 32 pierces the diaphragm of the cartridge, allowing filling of the cartridge. Attaching adapter 26b to the reusable unit 20 causes the drive mechanism within the reusable unit to be automatically triggered, moving forward a preset amount, forcing fluid out of the fluid cartridge 22b and through the needle in filling chamber 32. Filling can also be achieved in the manner described above as "by design". One reason for filling replacement cartridges is to overcome the initial friction of the cartridge plunger. It should be noted that the primary purpose of initial filling for a new disposable unit is to purge air from the cannula fluid path, which is different from the purpose of filling replacement cartridges and typically requires purging a larger amount of fluid. Another purpose of priming the initial fluid cylinder and the replacement fluid cylinder is to ensure proper attachment between the reusable unit and the cylinder plunger, avoiding gaps or preload between the reusable piston and the cylinder plunger, thereby eliminating the risk of under-dispensing or over-dispensing.

[0045] The primary purpose of the cartridge adapter described herein is to assist in ensuring that users follow the procedures required for filling replacement cartridges. As mentioned above, cartridge adapters are typically provided with the disposable unit and filling chamber. When a user uses a new disposable unit, the initial fluid cartridge is thus attached to the cartridge unit provided with the disposable unit from the outset. When the initial fluid cartridge is empty, the user must attach a new cartridge adapter to the replacement fluid cartridge. When the initial cartridge adapter is no longer usable (it is discarded along with the initial cartridge), the user obtains a new adapter for replacing the cartridge by attaching the replacement fluid cartridge to the filling chamber where the new cartridge adapter is provided. Therefore, this need for an adapter guides the user to attach the replacement cartridge to the filling chamber and thus fill the replacement cartridge before attaching the reusable unit with the replacement cartridge (and the new adapter) to the disposable unit.

[0046] In step 618, the user removes the infusion chamber 32 from the reusable unit. Since the adapter clip (described above) secures the adapter to the cartridge, the new cartridge adapter 26b is typically removed along with the replacement cartridge 22b and the reusable unit.

[0047] In step 620, the user slides the reusable unit 20, including the fluid cylinder 22b and the adapter 26b, onto the disposable unit 28 to reassemble the complete fluid delivery device 40b in step 622. A needle within the disposable unit 28 enters and passes through the diaphragm of the replacement fluid cylinder 22b, allowing the delivery of fluid (e.g., medications such as insulin) to continue through the cannula of the disposable unit.

[0048] Example

[0049] A first embodiment of a system for fluid delivery includes a fluid delivery device for discharging fluid from a fluid cylinder. The fluid delivery device includes a reusable unit and a disposable unit. The reusable unit includes a drive mechanism for discharging fluid from the fluid cylinder. The disposable unit has a sleeve for transferring the fluid discharged from the fluid cylinder to an external target such as a patient's body. The system also includes a cylinder adapter configured to facilitate a first connection between the reusable unit and the disposable unit, and additionally to facilitate an alternative connection between the reusable unit and an infusion chamber for infusing a replacement fluid cylinder.

[0050] Embodiment 2 of the system includes the features of the first embodiment, and the cylinder adapter includes a sleeve through which the diaphragm end of the fluid cylinder passes to attach the cylinder adapter to the fluid cylinder.

[0051] Embodiment 3 of the system includes some or all of the features of the embodiments described above, and further includes an infusion chamber. The infusion chamber includes a needle for infusing the fluid cylinder, and the infusion chamber is configured to connect to the reusable unit via a cylinder adapter.

[0052] Embodiment 4 of the system includes some or all of the features of the embodiments described above, and the reusable unit has at least one sensor for sensing the connection between the cartridge adapter and the filling chamber. The reusable unit is configured to discharge fluid from the fluid cartridge only when a sensor indication indicating that the cartridge adapter and the filling chamber are connected is received, in order to fill the fluid cartridge.

[0053] Embodiment 5 of the system includes some or all of the features of the above embodiments, and the reusable unit is configured to initiate the filling of the replacement fluid cylinder when a sensor indication is received that the cylinder adapter and the filling chamber are connected.

[0054] Embodiment 6 of the system includes some or all of the features of the embodiments described above, and the reusable unit is configured to have a command to discharge fluid into the sleeve. The reusable unit has at least one sensor for sensing the connection between the cylinder adapter and the disposable unit. The reusable unit is configured to execute the command to discharge fluid from the fluid cylinder into the sleeve only upon receiving a sensor indication that the cylinder adapter and the disposable unit are connected.

[0055] Embodiment 7 of the system includes some or all of the features of the embodiments described above, and the reusable unit has at least one sensor for sensing that the disposable unit is attached to a surface such as a patient's body. When the reusable unit detects that it has been attached to a disposable unit attached to a surface, fluid is discharged from the fluid cartridge only if the fluid cartridge has been previously infused.

[0056] System embodiment 8 includes some or all of the features of the above embodiments, and the dimensions of the cylinder adapter, disposable unit and reusable unit are configured to prevent the operation of the fluid delivery device unless the disposable unit and reusable unit are attached to the cylinder.

[0057] System embodiment 9 includes some or all of the features of the above embodiments, and the cylinder adapter has a snap-fit ​​for securing the cylinder adapter to the fluid cylinder to ensure that the cylinder adapter is removed when the fluid cylinder is removed from the disposable unit.

[0058] Embodiment 10 of the system includes some or all of the features of the above embodiments, and also includes an adhesive for adhering the disposable unit to the body.

[0059] Example 11 includes a cartridge adapter for a fluid delivery device comprising: 1) a reusable unit including a drive mechanism for discharging fluid from a fluid cartridge, and 2) a disposable unit including a sleeve for transferring fluid from the fluid cartridge to an external target such as a patient's body. The cartridge adapter is configured to facilitate a first connection between the reusable unit and the disposable unit, and additionally to facilitate an alternative connection between the reusable unit and an infusion chamber for infusing a replacement fluid cartridge.

[0060] Example 12 includes the features of Example 11, and the cylinder adapter further includes a sleeve for assembling the cylinder adapter onto the diaphragm end of the fluid cylinder, and a frame having connection points for facilitating a first connection with the disposable unit and an alternative connection with the infusion chamber.

[0061] Example 13 includes the features of Example 11, and the cartridge adapter is configured to attach to the diaphragm end of the fluid cartridge. The cartridge adapter also includes a snap-fit ​​for preventing the cartridge adapter from being removed from the fluid cartridge after attachment.

[0062] Example 14 describes a method for replacing a fluid delivery device, wherein the fluid delivery device includes a reusable unit and a disposable unit. The reusable unit includes a drive mechanism for discharging fluid from the fluid delivery device. The disposable unit has a sleeve for transferring fluid from the fluid delivery device to a surface such as a patient's body. The method includes the following steps:

[0063] - After the fluid delivery device is operated with the aid of the first fluid cylinder, the reusable unit and the first fluid cylinder are removed from the disposable unit while the disposable unit is still attached to the patient's body, while the fluid cylinder remains attached to the first cylinder adapter.

[0064] - Insert the replacement fluid cylinder into the reusable unit and connect the replacement fluid cylinder to the replacement cylinder adapter and then to the filling chamber to fill the replacement fluid cylinder;

[0065] - Remove the filling chamber from the replacement cylinder adapter, replacement fluid cylinder, and reusable unit; and

[0066] A reusable unit with a replaceable fluid cartridge and a replaceable cartridge adapter is connected to a disposable unit still attached to the patient's body for subsequent operations of the fluid delivery device using the replaceable fluid cartridge.

[0067] Example 15 includes the features of Example 14, and subsequent operation of the fluid delivery device includes discharging fluid from the replacement fluid cylinder to the sleeve of the disposable unit according to instructions configurable in the reusable unit.

Claims

1. A system for fluid transport, comprising: A fluid delivery device for discharging fluid from a fluid cylinder, the fluid delivery device comprising a reusable unit and a disposable unit, the reusable unit including a drive mechanism for discharging fluid from the fluid cylinder, and the disposable unit having a sleeve for conveying the fluid discharged from the fluid cylinder; as well as A cartridge adapter is configured to facilitate a first connection between the reusable unit and the disposable unit, and additionally facilitate an alternative connection between the reusable unit and the filling chamber, thereby filling the replacement fluid cartridge.

2. The system of claim 1, wherein the cylinder adapter includes a sleeve through which the diaphragm end of the fluid cylinder passes to attach the cylinder adapter to the fluid cylinder.

3. The system of claim 1, further comprising the infusion chamber, wherein the infusion chamber includes a needle for infusing the fluid cartridge, and wherein the infusion chamber is configured to connect to the reusable unit via the cartridge adapter.

4. The system of claim 1, wherein the reusable unit has at least one sensor for sensing the connection between the cylinder adapter and the filling chamber, and wherein the reusable unit is configured to discharge fluid from the fluid cylinder to fill the fluid cylinder only upon receiving a sensor indication that the cylinder adapter and the filling chamber are connected.

5. The system of claim 4, wherein the reusable unit is configured to initiate the filling of the replacement fluid cylinder upon receiving a sensor indication that the cylinder adapter and the filling chamber are connected.

6. The system of claim 1, wherein the reusable unit is configurable to have an instruction to discharge fluid into the sleeve, wherein the reusable unit has at least one sensor for sensing the connection between the cylinder adapter and the disposable unit; and the reusable unit is configured to execute the instruction to discharge fluid from the fluid cylinder into the sleeve only upon receiving a sensor indication that the cylinder adapter and the disposable unit are connected.

7. The system of claim 4, wherein the reusable unit has at least one sensor for sensing that the disposable unit is attached to a surface; and wherein, When the reusable unit senses that it has been attached to the disposable unit attached to the surface, the reusable unit discharges the fluid from the fluid cylinder only if the fluid cylinder has been previously filled.

8. The system of claim 1, wherein the dimensions of the cylinder adapter, the disposable unit, and the reusable unit are configured to prevent the fluid delivery device from operating unless the disposable unit and the reusable unit are attached to the cylinder.

9. The system of claim 1, wherein the cartridge adapter has a snap-fit ​​for securing the cartridge adapter to the fluid cartridge to ensure that the cartridge adapter is removed when the fluid cartridge is removed from the disposable unit.

10. The system for fluid transport according to claim 1, further comprising an adhesive for attaching the disposable unit to a surface.

11. A cylindrical adapter for a fluid delivery device, the fluid delivery device comprising: 1) a reusable unit including a drive mechanism for discharging fluid from the fluid cylinder, and 2) a disposable unit including a sleeve for conveying fluid from the fluid cylinder, wherein the cylinder adapter is configured to facilitate a first connection between the reusable unit and the disposable unit, and additionally facilitate an alternative connection between the reusable unit and the infusion chamber for infusing a replacement fluid cylinder.

12. The cylindrical adapter according to claim 11, further comprising: A sleeve for assembling the cylinder adapter onto the diaphragm end of the fluid cylinder; as well as A frame having connection sites for facilitating the first connection between the reusable unit and the disposable unit, and the alternative connection between the reusable unit and the infusion cavity.

13. The cartridge adapter of claim 11, wherein the cartridge adapter is configured to attach to the diaphragm end of the fluid cartridge, and wherein the cartridge adapter further includes a snap-fit ​​for preventing the cartridge adapter from being removed from the fluid cartridge after attachment.

14. A method for replacing a fluid cartridge of a fluid delivery device, wherein the fluid delivery device includes a reusable unit and a disposable unit, the reusable unit including a drive mechanism for discharging fluid from the fluid cartridge, and the disposable unit having a cannula for transferring fluid from the fluid cartridge to a patient's body, the method comprising: After the fluid delivery device is operated using the first fluid cylinder, the reusable unit and the first fluid cylinder are removed from the disposable unit while the disposable unit is still attached to the patient's body, while the fluid cylinder remains attached to the first cylinder adapter. Insert the replacement fluid cylinder into the reusable unit and connect the replacement fluid cylinder to the replacement cylinder adapter and to the filling chamber to fill the replacement fluid cylinder; Disconnect the infusion chamber from the replacement cylinder adapter, the replacement fluid cylinder, and the reusable unit; as well as The reusable unit having the replacement fluid cylinder and the replacement cylinder adapter is connected to the disposable unit still attached to the patient's body for subsequent operations of the fluid delivery device using the replacement fluid cylinder.

15. The method of claim 14, wherein the subsequent operation of the fluid delivery device comprises: According to instructions configurable in the reusable unit, fluid is discharged from the replacement fluid cylinder into the sleeve of the disposable unit.

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