A composition with high efficient skin barrier repair ability, its preparation method and application

Abstract

The application provides a composition with high skin barrier repair ability, a preparation method and application thereof, and relates to the technical field of cosmetics. The composition with high skin barrier repair ability comprises active ingredient (a) adiantum capillus-veneris leaf extract and at least one of active ingredient (b) aesculus hippocastanum extract, lycium barbarum fruit extract and salvia miltiorrhiza nanomicelle. The composition has multiple effects of anti-inflammation, moisturization and skin barrier repair through the synergistic combination of adiantum capillus-veneris leaf extract and component (b). The adiantum capillus-veneris leaf extract as a synergistic trigger core can effectively relieve skin inflammatory response, enhance skin water retention capacity and promote the recovery and reconstruction of damaged skin barrier function in cooperation with one or more of aesculus hippocastanum extract, lycium barbarum fruit extract or salvia miltiorrhiza nanomicelle. The composition has good stability and is suitable for various soothing and repairing cosmetics.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, and in particular to a composition with highly effective skin barrier repair capabilities, its preparation method, and its application. Background Technology

[0002] As the body's first line of defense against external aggressors, the skin barrier's health is crucial to overall skin function. However, in the modern environment, factors such as UV radiation, chemical irritation, microbial infections, and excessive cleansing can easily damage the skin barrier, leading to problems like inflammation, dryness, and sensitivity. Consequently, the market demand for functional skincare products that combine high-efficiency repair, moisturizing, anti-inflammation, and enhanced skin barrier function is increasing daily.

[0003] Currently, skin barrier repair products and related technologies mainly suffer from the following problems: Existing technologies often focus on single effects, such as simply emphasizing anti-inflammation or moisturizing, lacking a deep integration of the synergistic effects of "anti-inflammation, moisturizing, and repair." Some products rely on single active ingredients with limited target areas, resulting in poor repair effects; and when different ingredients are combined, improper proportions or poor synergy often make it difficult to achieve effective synergy, and may even produce antagonistic effects, affecting the final result.

[0004] The scientific formulation of ingredients from multiple sources (plants, microorganisms, or synthetic compounds, etc.) with multiple functions (such as antibacterial and anti-inflammatory, moisturizing and repairing) to build a stable and efficient skin barrier repair system remains a key technical challenge that the industry urgently needs to overcome. Specifically, plant extracts have significant potential in anti-inflammatory and soothing effects, but single extracts are usually insufficient to address complex skin problems; while conventional moisturizing and repairing ingredients such as collagen, although providing some basic moisturizing effects, are difficult to achieve deep synergy with highly effective soothing and barrier repair systems.

[0005] Therefore, developing a composition that can integrate effective ingredients from multiple sources and achieve synergistic effects of anti-inflammation, moisturizing, and repair through precise compounding, thereby strengthening the skin barrier function from multiple dimensions, has become an urgent need in the field of skin care.

[0006] In view of this, the present invention is hereby proposed. Summary of the Invention

[0007] The first objective of this invention is to provide a composition with highly efficient skin barrier repair capabilities. This composition, through the synergistic combination of at least one of maidenhair fern leaf extract, horse chestnut extract, wolfberry fruit extract, and tanshinone nanomicelles, can effectively alleviate skin inflammation, enhance skin's water-locking ability, and promote the recovery and reconstruction of damaged skin barrier function.

[0008] A second objective of this invention is to provide a method for preparing a composition with highly efficient skin barrier repair capabilities.

[0009] A third objective of this invention is to provide an application of a composition with highly efficient skin barrier repair capabilities.

[0010] In order to achieve the above-mentioned objectives of the present invention, the following technical solution is adopted: According to one aspect of the present invention, a composition having highly effective skin barrier repair capabilities, the composition comprising active ingredient (a) and active ingredient (b), specifically as follows: (a) Adiantum leaf extract; (b) At least one of horse chestnut extract, wolfberry fruit extract, and tanshinone nanomicelles.

[0011] The present invention provides a composition with highly efficient skin barrier repair capabilities. This composition, through the synergistic combination of at least one of *Adiantum capillus-veneris* leaf extract, *Aesculus hippocastanum* extract, *Lycium barbarum* fruit extract, and *Salvia miltiorrhiza* nanomicelles, can exert multiple effects including anti-inflammatory, moisturizing, and skin barrier repair. Specifically, *Adiantum capillus-veneris* leaf extract, as a synergistic trigger, works in conjunction with one or more of the ingredients in *Aesculus hippocastanum* extract, *Lycium barbarum* fruit extract, and *Salvia miltiorrhiza* nanomicelles to effectively alleviate skin inflammation, enhance skin's water-locking ability, and promote the recovery and reconstruction of damaged skin barrier function.

[0012] In a preferred embodiment of the present invention, the preparation method of the maidenhair fern leaf extract includes: pulverizing maidenhair fern leaves, adding 8 to 15 times the amount of alcohol solution, soaking for 0.5 to 2 hours for extraction, and then filtering to obtain the maidenhair fern leaf extract.

[0013] In a preferred embodiment of the present invention, the alcohol solution includes one of ethanol solution, 1,3-propanediol solution, propylene glycol solution, butanediol solution, 1,2-hexanediol solution or glycerol solution.

[0014] In the preferred embodiment described above, the alcohol solution is a mixture of 70% butanediol and 30% water.

[0015] As a preferred embodiment, the maidenhair fern leaf extract is obtained by extraction and filtration using a mixed solution of 70% butylene glycol and 30% water. It has good anti-inflammatory, antioxidant and skin-soothing activities and can synergistically exert a skin barrier repair effect with other components.

[0016] In a preferred embodiment of the present invention, the extraction is reflux extraction or ultrasonic extraction, and the temperature of the reflux extraction or ultrasonic extraction is 60~80℃; Preferably, the extraction is ultrasonic extraction at a temperature of 60°C.

[0017] In a preferred embodiment of the present invention, the weight ratio of active ingredient (a) to active ingredient (b) is 0.1:(1~10).

[0018] In a preferred embodiment, the active ingredient (a) and active ingredient (b) are compounded in a weight ratio of 0.1:(1 to 10) to achieve synergistic effects of anti-inflammatory, moisturizing and skin barrier repair functions, enhance the skin's tolerance to external stimuli, and effectively prevent and / or repair skin barrier damage.

[0019] In a preferred embodiment of the present invention, the active ingredient (b) is composed of horse chestnut extract, wolfberry fruit extract, and tanshinone nanomicelles; In the preferred embodiment described above, the mass ratio of the horse chestnut extract, the wolfberry fruit extract, and the tanshinone nanomicelles is (1~10):(1~10):(0.1~1). Preferably, the mass ratio of the horse chestnut extract, wolfberry fruit extract, and tanshinone nanomicelles is 3:7:0.1.

[0020] In a preferred embodiment of the present invention, the composition further comprises a commonly used soothing and moisturizing composition; In a preferred embodiment, the composition further comprises a commonly used soothing and moisturizing composition that can synergize with active ingredients (a) and (b) to further enhance the moisturizing effect, improve the integrity and stability of the skin barrier, and enhance the overall repair efficacy.

[0021] In the preferred embodiment described above, the commonly used soothing and moisturizing composition comprises mussel extract, collagen, panthenol, and sodium DNA, wherein the weight ratio of mussel extract, collagen, panthenol, and sodium DNA is 7-15:15-30:15-30:0.1-0.5. Preferably, the weight ratio of the mussel extract, collagen, panthenol, and sodium DNA is 12.5:25:25:0.1.

[0022] According to one aspect of the present invention, a method for preparing the above-mentioned composition with highly efficient skin barrier repair ability, the preparation method comprising: The active ingredients (a) and (b) are mixed evenly to obtain a composition with highly effective skin barrier repair capabilities.

[0023] The present invention provides a method for preparing a composition with highly efficient skin barrier repair capabilities, which has the technical advantages of simple processing and easy operation.

[0024] Optionally, the preparation method further includes the step of adding a commonly used soothing and moisturizing composition to the obtained composition with high skin barrier repair capabilities and mixing them evenly.

[0025] According to one aspect of the present invention, the use of the composition having highly effective skin barrier repair capabilities described above according to the present invention in the preparation of cosmetics for repairing the skin barrier, moisturizing or anti-inflammatory purposes.

[0026] The present invention provides the application of a composition with highly efficient skin barrier repair capabilities. This composition can be used to prepare cosmetics with skin barrier repair, moisturizing and anti-inflammatory effects, and can synergistically improve skin dryness, redness and other barrier-related problems, and enhance skin tolerance and overall health.

[0027] According to one aspect of the present invention, a cosmetic product comprises: the composition of the present invention described above having highly effective skin barrier repair capabilities and a cosmetically acceptable carrier; The present invention provides a cosmetic product that, by comprising the composition of the present invention having a highly effective skin barrier repair capability, can achieve synergistic repair of the skin barrier, and has anti-inflammatory, moisturizing and soothing effects, improves skin sensitivity, dryness and discomfort caused by external stimuli, and enhances the product's comfort and repair performance.

[0028] Preferably, the cosmetic is any one of serum, lotion, cream, mask, or toner.

[0029] Compared with the prior art, the beneficial effects of the present invention are as follows: The present invention provides a composition with highly efficient skin barrier repair capabilities. This composition, through the synergistic combination of at least one of *Adiantum capillus-veneris* leaf extract, *Aesculus hippocastanum* extract, *Lycium barbarum* fruit extract, and *Salvia miltiorrhiza* nanomicelles, can exert multiple effects including anti-inflammatory, moisturizing, and skin barrier repair. Specifically, *Adiantum capillus-veneris* leaf extract, as a synergistic trigger, works in conjunction with one or more of the ingredients in *Aesculus hippocastanum* extract, *Lycium barbarum* fruit extract, and *Salvia miltiorrhiza* nanomicelles to effectively alleviate skin inflammation, enhance skin's water-locking ability, and promote the recovery and reconstruction of damaged skin barrier function.

[0030] The present invention provides a method for preparing the above-mentioned composition with high skin barrier repair ability, which has the technical advantages of simple processing and easy operation.

[0031] The present invention provides an application of the above-mentioned composition with highly efficient skin barrier repair capabilities. This composition can be used to prepare cosmetics with skin barrier repair, moisturizing and anti-inflammatory effects, and can synergistically improve skin dryness, redness and other barrier-related problems, and enhance skin tolerance and overall health.

[0032] The present invention provides a cosmetic product that, by comprising the composition of the present invention having a highly effective skin barrier repair capability, can achieve synergistic repair of the skin barrier, and has anti-inflammatory, moisturizing and soothing effects, improves skin sensitivity, dryness and discomfort caused by external stimuli, and enhances the product's comfort and repair performance. Detailed Implementation

[0033] The technical solution of the present invention will be clearly and completely described below with reference to the embodiments. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0034] The technical solution of the present invention will be further described below with reference to the embodiments.

[0035] Note: All components in this application were provided by Baiyun Meiwan Medical Beauty International Cosmetic Research Institute, including maidenhair fern leaf extract, horse chestnut extract, wolfberry fruit extract, tanshinone nano micelles, mussel extract, collagen, panthenol, sodium DNA, gentian extract, and tremella extract.

[0036] Among them, the extracts of maidenhair fern leaves and wolfberry fruit were extracted from medicinal materials purchased by Baiyun Meiwan Medical Beauty International Cosmetics, and the extraction solvents were water or butylene glycol.

[0037] Specifically: 1. The extraction method of the maidenhair fern leaf extract is as follows: Take maidenhair fern leaves, crush them, add a mixed alcohol solution (70% butanediol and 30% water by volume) equivalent to 10 times the volume of the maidenhair fern leaf raw material, and soak for 1 hour; then extract using any of the following methods: (a) Reflux extraction: Heat and reflux at 60℃ for 0.5h to 1.5h, then filter and collect the filtrate; (b) Ultrasonic extraction: Ultrasonic extraction at 40 kHz at 60 °C for 0.5 h to 1.5 h, followed by filtration to collect the filtrate; Note: The example uses an extraction time of 1.0h, but in practice, the extraction time can be adjusted within the range of 0.5h to 1.5h according to production needs, and all of these can achieve the purpose of this invention.

[0038] Finally, the volume was adjusted to 10 times the mass of the maidenhair fern leaf raw material using the extraction solvent (a mixed alcoholic solution of 70% butanediol and 30% water) to obtain the maidenhair fern leaf extract, which was stored at room temperature away from light for later use.

[0039] 2. The extraction method of the wolfberry fruit extract is as follows: Take wolfberry fruit, crush it, and add a mixed alcohol solution (70% butanediol and 30% water by volume) equivalent to 10 times the weight of the wolfberry fruit raw material, and soak for 1 hour; then extract using any of the following methods: (a) Reflux extraction: Heat and reflux at 60℃ for 0.5h to 1.5h, then filter and collect the filtrate; (b) Ultrasonic extraction: Ultrasonic extraction at 40 kHz at 60 °C for 0.5 h to 1.5 h, followed by filtration to collect the filtrate; Note: The example uses an extraction time of 1.0h, but in practice, the extraction time can be adjusted within the range of 0.5h to 1.5h according to production needs, and all of these can achieve the purpose of this invention.

[0040] Finally, the volume was adjusted to 10 times the mass of the wolfberry fruit raw material using an extraction solvent (a mixed alcoholic solution of 70% butanediol and 30% water) to obtain the wolfberry fruit extract, which was then stored at room temperature away from light for later use.

[0041] 3. The Danshen nano micelles mentioned are commercially available products, with the trade name Ganyin Qingdou. The supplier is Sida (Guangdong) Biomedical Technology Co., Ltd., and the product batch number in the patent test is GDSDY250731. 4. The supplier of horse chestnut extract is Star (Guangdong) Biomedical Technology Co., Ltd., and the product batch number in the patent test is 20260108; 5. The supplier of mussel extract is Sida (Guangdong) Biomedical Technology Co., Ltd., and the product batch number in the patent test is 20260124; 6. The collagen supplier is Star (Guangdong) Biomedical Technology Co., Ltd., and the product batch number in the patent test is 2026011601; 7. The supplier of panthenol is Star (Guangdong) Biomedical Technology Co., Ltd., and the product batch number in the patent test is 20250924; 8. The supplier of DNA sodium is Star (Guangdong) Biomedical Technology Co., Ltd., and the product batch number in the patent test is 20260120; 9. The supplier of gentian extract is Sida (Guangdong) Biomedical Technology Co., Ltd., and the product batch number in the patent test is 20250801; 10. The supplier of Tremella fuciformis extract is Sida (Guangdong) Biomedical Technology Co., Ltd., and the product batch number in the patent test is A2522343.

[0042] Example 1 A composition with highly effective skin barrier repair capabilities, the composition comprising: Weigh each component according to the parts by weight in Table 1, mix them in a clean beaker, and vortex or stir at room temperature until uniformly dispersed to obtain the composition.

[0043] Table 1:

[0044] Note: In the table above, " / " represents 0, meaning that the substance is not included.

[0045] The hyaluronidase activity and in vitro moisturizing rate of the composition were then tested, as follows: (I) Test method for hyaluronidase activity in this embodiment: Referring to the reagent addition amounts in Table 2, add calcium chloride solution, hyaluronidase solution, and pH 5.6 acetate buffer to each tube sequentially, mix thoroughly, and incubate at 37°C for 20 min; add the sample or pH 5.6 acetate buffer, mix thoroughly, and incubate again at 37°C for 20 min; add sodium hyaluronate solution, incubate at 37°C for 30 min, and then place at room temperature for 5 min; then add sodium hydroxide solution and acetylacetone solution sequentially, incubate in a boiling water bath (100°C) for 15 min, and then in an ice bath (0°C) for 5 min; add Ehrlich reagent, shake to mix, add 3.0 M anhydrous ethanol, incubate at room temperature for 20 min, and measure the absorbance at 530 nm.

[0046] The formula for calculating the inhibition rate is: Inhibition rate (%) = [1 - (cd) / (ab)] × 100%; In the formula, a is the absorbance of the enzyme reaction tube (tube A); b is the absorbance of the solvent background (tube B); c is the absorbance of the sample tube (tube C); and d is the absorbance of the sample background (tube D).

[0047] Table 2 Sample dosage for hyaluronidase inhibition test:

[0048] Note: In the table above, " / " represents 0, meaning that the substance is not included.

[0049] (II) Test method for in vitro moisturizing test in this embodiment: Pipette 2.0 mL of each sample into a weighing bottle, and place each weighing bottle in a desiccant container (relative humidity RH = 45%) fitted with a blue silica gel desiccant at the bottom. The temperature for all tests was controlled at 25 ± 1 ℃, and weighing was performed at 4 h. All tests were performed in triplicate, and the average value was taken. The moisture retention rate (Rh) was calculated using the formula. The specific calculation formula is as follows: ; In the formula, M0 is the initial mass of the sample in the weighing bottle; Mt is the mass of the sample in the weighing bottle at the 4th hour.

[0050] Comparative Example 1 This comparative test examines the moisturizing and repairing abilities of different component combinations, compares them with different composition samples, and analyzes the effects of different component combinations and the absence of a certain component on the efficacy of Example 1.

[0051] A composition with highly effective skin barrier repair capabilities, the composition comprising: Weigh each component according to the 3 parts by weight in Table 3, mix them in a clean beaker, and vortex or stir at room temperature until uniformly dispersed to obtain the composition.

[0052] Table 3:

[0053] Note: In the table above, " / " represents 0, meaning that the substance is not included.

[0054] The test methods for the hyaluronidase activity inhibition rate and in vitro moisturizing rate of this comparative example are the same as those in Example 1.

[0055] As can be seen from Example 1 and Comparative Example 1 above, in achieving the skin barrier repair effect, the maidenhair fern leaf extract of this application does not participate in a simple addition as a conventional active ingredient, but rather plays a unique synergistic regulatory role. When the system does not contain maidenhair fern leaf extract (the compositions in the comparative examples that do not contain maidenhair fern leaf extract), regardless of whether horse chestnut extract, wolfberry fruit extract, or tanshinone nanomicelles are used alone, or combined in pairs or triplets in different proportions, the highest hyaluronidase inhibition rate is only 62.19%, and the highest in vitro 4-hour moisturizing rate is only 88.33%. However, once a trace amount of maidenhair fern leaf extract (0.1 parts) was introduced, the anti-inflammatory and moisturizing properties were significantly improved even with low amounts of other components. For example, the combination containing only 0.1 parts of maidenhair fern leaf extract and 3 parts of horse chestnut extract (composition 2) achieved an inhibition rate of 66.14% and a moisturizing rate of 92.49%, which exceeded the best single-component results in the comparative example by 4.4 percentage points and 4.16 percentage points, respectively.

[0056] Crucially, this synergistic effect exhibits a significant leap when multiple components are precisely matched. When maidenhair fern leaf extract (0.1 parts) is co-present with horse chestnut extract (3 parts), wolfberry fruit extract (7 parts), and tanshinone nanomicelles (0.1 parts) (composition 12 in Example 1), the hyaluronidase inhibition rate increases to 77.2%, and the in vitro moisturizing rate reaches 96.17%, which is approximately 15 percentage points and nearly 8 percentage points higher, respectively, than all formulations in the comparative example that do not contain maidenhair fern leaf extract. This increase far exceeds the expected linear additive effect of the individual components.

[0057] Furthermore, the experimental data also reflected a clear ratio sensitivity: with the maidenhair fern leaf extract fixed at 0.1 parts, the inhibition rate increased from 62.99% to 66.14% when the amount of horse chestnut extract was increased from 1 part to 3 parts (composition 1, composition 2); however, when it was further increased to 5 parts (composition 3), the inhibition rate dropped to 63.34%, indicating the existence of a response threshold. Similarly, the inhibition rate of the wolfberry fruit extract reached a peak of 66.59% at 7 parts (composition 8), but dropped back to 62.73% after increasing to 10 parts (composition 9). Considering the phenomenon that tanshinone must be introduced in the form of nanomicelles (rather than ordinary extracts) to stably participate in this synergistic system (compositions 9, 12, 13, and 14), the moisturizing rate was ≥94.55%, while the highest moisturizing rate in Comparative Example 1 without nanomicelles was only 88.33%.

[0058] Comparative Example 2 Gentian extract was selected to replace maidenhair fern leaf extract in component a to verify the effect of the changed ingredients on moisturizing and repairing activities.

[0059] A composition with highly effective skin barrier repair capabilities, the composition comprising: Weigh each component according to the four parts by weight in Table 4, mix them in a clean beaker, and vortex or stir at room temperature until uniformly dispersed to obtain the composition.

[0060] Table 4:

[0061] Note: In the table above, " / " represents 0, meaning that the substance is not included.

[0062] The test methods for the hyaluronidase activity inhibition rate and in vitro moisturizing rate of this comparative example are the same as those in Example 1.

[0063] As shown in Table 4 above, when gentian extract is used to replace maidenhair fern leaf extract in equal amounts (composition 36 in Comparative Example 2), even if the same ratio (0.1:3:7:0.1) is maintained, the inhibition rate drops sharply to 12.58%, and the moisturizing rate is only 83.31%. This indicates that the synergistic response is highly dependent on specific chemical components in maidenhair fern leaf extract, rather than the general properties of plant extracts.

[0064] Example 2 In this embodiment, based on the composition with highly effective skin barrier repair capabilities of "Composition 12" in Example 1, a commonly used soothing and moisturizing composition is added. The following weight parts are weighed and mixed, and the mixture is vortexed or stirred at room temperature until uniformly dispersed to obtain the composition of this embodiment. The specific composition is as follows: The composition of “Composition 12” in Example 1 consists of 1 part of a composition with highly effective skin barrier repair capabilities, 12.5 parts of mussel extract, 25 parts of collagen, 25 parts of panthenol, and 0.1 parts of sodium DNA.

[0065] The composition of this embodiment was tested according to the test methods of hyaluronidase activity inhibition rate (%) and moisturizing rate (%) in Example 1, and the hyaluronidase activity inhibition rate was 88.88% and the moisturizing rate was 97.39%.

[0066] Compared with the results of composition 12 in Example 1, composition 12 showed a further enhanced effect when combined with commonly used soothing compositions, indicating a synergistic effect.

[0067] Comparative Example 3 This comparative example is identical to Example 2, except that the maidenhair fern leaf extract in the composition of Example 2, which has a high skin barrier repair capability, is replaced with an equal amount of gentian extract.

[0068] The composition of this embodiment was tested according to the test methods of hyaluronidase activity inhibition rate (%) and moisturizing rate (%) in Example 1, and the hyaluronidase activity inhibition rate was 71.99% and the moisturizing rate was 88.12%.

[0069] Compared with the results of composition 12 in Example 1, replacing maidenhair fern leaf extract with gentian extract in an equal amount and then combining it with commonly used soothing compositions failed to achieve the expected effect. This indicates that the synergistic response is highly dependent on specific chemical components in maidenhair fern leaf extract, rather than the general properties of plant extracts.

[0070] Comparative Example 4 In this comparative example, based on the composition with highly efficient skin barrier repair ability of "Composition 12" in Example 1, tremella extract was added, weighed and mixed according to the following weight parts, and vortexed or stirred at room temperature until uniformly dispersed to obtain the composition of this comparative example, as detailed in Table 5.

[0071] Table 5:

[0072] Note: The test methods for the hyaluronidase activity inhibition rate and in vitro moisturizing rate of this comparative example are the same as those in Example 1.

[0073] As shown in the table above, this comparative example used Tremella fuciformis extract to replace the commonly used soothing and moisturizing composition in Example 2. As the amount of Tremella fuciformis extract increased from 1 part to 20 parts, the hyaluronidase inhibition rate slowly increased from 59.66% to 63.53%, while the in vitro 4-hour moisturizing rate gradually decreased from 92.85% to 90.59%. It is noteworthy that all combinations containing Tremella fuciformis extract (compositions 39-42) showed lower anti-inflammatory and moisturizing effects than the inhibition and moisturizing rates measured in Example 2 (containing the soothing and moisturizing composition). This indicates that although Tremella fuciformis extract has a certain moisturizing ability, its addition does not induce the synergistic effect of composition 12 in Example 1.

[0074] In Example 2, the specific combination of mussel extract, collagen, panthenol and sodium DNA, without disrupting the original synergistic system, effectively extends and strengthens the main repair pathway through multiple mechanisms such as supplementing extracellular matrix components, promoting stratum corneum lipid synthesis and stabilizing barrier protein conformation, and has better compatibility with Composition 12.

[0075] Application Example 1 Consumer testing was conducted on cosmetic compositions 42 from Examples 2, 3, and 4 to assess their effectiveness in repairing essence water products. The weight parts of each component of the repairing toner are shown in Table 6.

[0076] (1) Its preparation method includes the following steps: S1. Add phase A water to the main pot, add the remaining components of phase A in sequence under homogenization, start stirring and heat to 80~85℃, then start homogenization and dispersion until complete, keep the temperature constant for 15 minutes, and set aside. S2. Add phase B sequentially, and after complete homogenization and emulsification, start stirring and cooling. S3. Cool down to 38℃, stop stirring, and take samples for testing; S4, Qualified, Discharge.

[0077] Table 6: Simple Recipe for Brightening and Renewing Essence Water:

[0078] Note: In the table above, " / " represents 0, meaning that the substance is not included.

[0079] (2) Consumer testing: Ninety male and female volunteers aged 18 to 50 were recruited (selection criteria were healthy volunteers with dry and red skin), with 30 people in each group. The repairing toner was used every other day (once every two days) for four consecutive weeks. Evaluation was based on two aspects: skin hydration and redness reduction effect (including the volunteers' soothing experience). The rating range was 0-7 (7 for extremely satisfied, 6 for very satisfied, 5 for fairly satisfied, 4 for neutral, 3 for somewhat dissatisfied, 2 for very dissatisfied, and 1 for extremely dissatisfied). Higher satisfaction indicated a higher score. Overall satisfaction refers to the percentage of participants who rated it 5-7. The consumer test results are shown in Table 7.

[0080] Table 7 Consumer Test Results:

[0081] As shown in Table 7, the skin feel, stability, hydration, and redness-reducing effect of the sample prepared in Example 2 were all recognized by consumers, who believed it produced good results, was easily absorbed, and was stable. However, consumers considered the skin feel, hydration, and redness-reducing effect of the essence water sample in Comparative Example 3 and Composition 42 to be only average.

[0082] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A composition with highly efficient skin barrier repair capabilities, characterized in that, The composition comprises active ingredient (a) and active ingredient (b), as detailed below: (a) Adiantum leaf extract; (b) At least one of horse chestnut extract, wolfberry fruit extract, and tanshinone nanomicelles.

2. The composition with highly efficient skin barrier repair capability according to claim 1, characterized in that, The preparation method of the maidenhair fern leaf extract includes: After crushing the leaves of maidenhair fern, add 8 to 15 times the amount of alcohol solution, soak for 0.5 to 2 hours, and then extract. After filtration, the extract of maidenhair fern leaves is obtained.

3. The composition with highly efficient skin barrier repair capability according to claim 2, characterized in that, The alcohol solution includes one of the following: ethanol solution, 1,3-propanediol solution, propylene glycol solution, butanediol solution, 1,2-hexanediol solution, or glycerol solution; Preferably, the alcohol solution is a mixture of 70% butanediol and 30% water.

4. The composition with highly efficient skin barrier repair capability according to claim 2, characterized in that, The extraction is reflux extraction or ultrasonic extraction, and the temperature of the reflux extraction or ultrasonic extraction is 60~80℃. Preferably, the extraction is ultrasonic extraction at a temperature of 60°C.

5. The composition with highly efficient skin barrier repair capability according to claim 1, characterized in that, The weight ratio of active ingredient (a) to active ingredient (b) is 0.1:(1~10).

6. The composition with highly efficient skin barrier repair capability according to claim 1, characterized in that, The active ingredient (b) is composed of horse chestnut extract, wolfberry fruit extract, and tanshinone nanomicelles; Preferably, the mass ratio of the horse chestnut extract, wolfberry fruit extract, and tanshinone nanomicelles is (1~10):(1~10):(0.1~1). Preferably, the mass ratio of the horse chestnut extract, wolfberry fruit extract, and tanshinone nanomicelles is 3:7:0.

1.

7. The composition with highly efficient skin barrier repair capability according to claim 1, characterized in that, The composition also includes commonly used soothing and moisturizing compositions; Preferably, the commonly used soothing and moisturizing composition comprises mussel extract, collagen, panthenol, and sodium DNA, wherein the weight ratio of mussel extract, collagen, panthenol, and sodium DNA is 7~15:15~30:15~30:0.1~0.

5. More preferably, the weight ratio of the mussel extract, collagen, panthenol and sodium DNA is 12.5:25:25:0.

1.

8. A method for preparing a composition with highly efficient skin barrier repair ability according to any one of claims 1 to 7, characterized in that, The preparation method includes: The active ingredient (a) and active ingredient (b) are mixed evenly to obtain a composition with highly efficient skin barrier repair capabilities; Optionally, the preparation method further includes the step of adding a commonly used soothing and moisturizing composition to the obtained composition with high skin barrier repair capabilities and mixing them evenly.

9. The use of a composition having highly effective skin barrier repair capabilities according to any one of claims 1 to 7 in the preparation of cosmetics for repairing the skin barrier, moisturizing or reducing inflammation.

10. A cosmetic product, characterized in that, The cosmetic comprises: the composition with highly effective skin barrier repair capabilities as described in any one of claims 1 to 7, and a cosmetically acceptable carrier; The cosmetic product is any one of the following: serum, lotion, cream, mask, or toner.

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