A composition for nourishing and moisturizing cinnamomum loureiroi and its preparation method and application
Patent Information
- Application Number
- CN202611049450.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-07-15
- Publication Date
- 2026-10-09
AI Technical Summary
[0007]本申请实施例提供一种姜柏养润的组合物及其制备方法和应用,以解决或缓解上面提出的一项或更多项技术问题
1、通过生长剂从源头减少DHT的持续生成,减少毛囊逐渐萎缩的情况;发用调理剂中的姜提取物和侧柏叶提取物占比大于50%,姜提取物同步改善微循环,为毛囊提供修复所需的血氧供给,侧柏叶提取物通过激活Wnt/β-catenin信号通路启动毛囊由休止期向生长期转换;两者相互协同配合使用,在促进毛干增粗、增加生长期毛囊比例、减少退行期毛囊数量方面产生了促新生与防再损的协同增效作用;实现了促再生与防损伤,既恢复已萎缩毛囊的功能,又改善了新生毛囊再次受损的情况,从而从根本上改善了头发呈细软塌稀发的缺陷;
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Abstract
Description
Technical Field
[0001] This application relates to the field of nursing product technology, and in particular to a ginger and cypress nourishing composition, its preparation method and application. Background Technology
[0002] Hair, as an integral part of the body structure, plays a vital role in our daily lives. Firstly, it directly protects the scalp, cushioning external forces and reducing damage, thus protecting the head. Simultaneously, hair has a crucial aesthetic function and unique, important socio-psychological significance. Traditional Chinese medicine believes that hair is an extension of blood, and that the kidneys store essence, which manifests in the hair. Hair growth depends on the nourishment of essence and blood; thick, shiny hair represents health and contributes to a positive image. Different hair shapes and conditions create different impressions, and healthy, beautiful hair boosts confidence in interpersonal interactions. Conversely, various hair-related conditions, such as hair loss, thinning hair, and dandruff, can lead to feelings of inferiority and anxiety, and in severe cases, even affect social activities. Therefore, it is essential to pay attention to hair care in daily life.
[0003] Shampoo is a type of hair cosmetic primarily used to cleanse the scalp and hair of bodily secretions, sweat, shed scalp cells, and external dust, microorganisms, styling product residue, and unpleasant odors, thus maintaining scalp and hair cleanliness and a beautiful appearance. With the increasing prevalence of factors such as staying up late, endocrine disorders, and high-fat diets, the number of people with seborrheic alopecia, fine, limp, and thinning hair continues to expand. Clinical survey data from the "China Scalp Microecology Research Report 2025" shows that over 70% of young and middle-aged people experiencing hair loss also experience fine hair strands, flat hair roots, and a sparse visual parting. Hair physiology testing indicates that fine, soft hair strands have insufficient keratin reserves and extremely poor mechanical support; coupled with excessive sebum secretion, the sebum continuously coats the hair roots and clogs the hair follicles, creating a vicious cycle of oil production—follicle atrophy—thinning, brittle, and flattened hair, ultimately manifesting as a widened parting, a flat crown, significant hair loss during washing and combing, recurring dandruff, and a sensitive, red scalp.
[0004] In related technologies, physical means (electric perming, hot air blow-drying, wigs) are generally used to temporarily cover the hair visually. Perming can damage the hair cuticle, making the hair more fragile and prone to breakage. Wigs can easily clog the scalp and aggravate oiliness and inflammation. However, these methods are irreversible damaging operations to the hair. Long-term use will cause the tensile strength of the hair to decrease sharply, which will further aggravate the vicious cycle of fine, soft and limp hair.
[0005] In summary, the inventors believe that the relevant technologies have the drawback of being unable to effectively improve the condition of thin, soft, limp, and sparse hair.
[0006] It should be noted that the above content is not necessarily prior art, nor is it intended to limit the scope of patent protection of this application. Summary of the Invention
[0007] This application provides a ginger and cypress nourishing composition, its preparation method, and its application to solve or alleviate one or more of the technical problems mentioned above.
[0008] In a first aspect, embodiments of this application provide a ginger and cypress nourishing composition, comprising the following raw materials in parts by weight: Use 5.05~11.95 parts of hair conditioner; Moisturizer 1.5~5.5 parts; Growth agent 0.5~15 parts; Anti-hair loss agent: 0.6-8 parts; Hair-strengthening agent: 0.02~1 part; Repair agent 0.8~10 parts; 0.5-5 parts of regulator; 50.75~60.25 parts of deionized water; The hair conditioning agent is a combination of Platycladus orientalis leaf extract, Polygonum multiflorum root extract, Angelica sinensis extract, ginseng root extract, Anemarrhena asphodeloides root extract, and ginger extract; and the total weight of the ginger extract and the Platycladus orientalis leaf extract accounts for more than 50% of the total weight of the hair conditioning agent. The growth agent is one or more of the following: β-sitosterol, sargassum sterol, saw palmetto extract, and neophytadiene modified solution.
[0009] Optionally, the repair agent includes one or more of the following: Sapindus mukorossi pericarp extract, milk thistle seed extract, and nicotinamide.
[0010] Optionally, the regulator includes one or more of lignin, chitin, chitosan, sophorolipid, and microfibrillated cellulose.
[0011] Optionally, when the repair agent is Sapindus mukorossi pericarp extract, the regulator is lignin, and the weight ratio of Sapindus mukorossi pericarp extract to lignin is 1:(0.1~0.8).
[0012] Optionally, the hair-fixing agent comprises one or a combination of two of gallic acid catechin gallate and fully acetylated green tea extract.
[0013] Optionally, the preparation method of the neophytadiene modified solution is as follows: dissolve neophytadiene in a solubilizer and mix evenly to form a neophytadiene modified solution; The weight ratio of the neophytadiene to the solubilizer is 1:(3~10); the solubilizer includes one or more of PEG-40 hydrogenated castor oil, polysorbate-80 and oleyl alcohol polyether-20.
[0014] Optionally, the anti-hair loss agent includes one or a combination of two of the following: enzyme-converted Sophora flavescens extract and Lactobacillus soymilk fermentation product.
[0015] Optionally, the humectant is butylene glycol, 1,2-hexanediol and octyl glycol, wherein the weight ratio of butylene glycol, 1,2-hexanediol and octyl glycol is (34~36):(0.35~0.65):(0.35~0.65).
[0016] Secondly, embodiments of this application provide a method for preparing a ginger and cypress nourishing composition, comprising the following steps: S1: Weigh out the corresponding hair conditioning agent and moisturizer according to the weight parts, stir and disperse them at room temperature until there are no particles, then put them into deionized water, stir at 40~60℃ until completely dissolved and transparent, keep warm for later use, and obtain an aqueous phase mixture. S2: Weigh the corresponding growth agent into a container according to the weight parts and stir evenly at 50~70℃ to obtain an oil phase mixture; S3: Under stirring conditions, slowly add the oil phase mixture obtained in step S2 to the aqueous phase mixture obtained in step S1, then homogenize and emulsify for 10-30 minutes, then cool to 35-45℃, then add the anti-hair loss agent and repair agent and stir for 5-10 minutes, then add the hair-fixing agent and stir in the dark for 8-15 minutes, finally add the regulator and stir until completely dispersed and without lumps, then discharge the material after stirring evenly to obtain the ginger and cypress nourishing composition.
[0017] Thirdly, embodiments of this application provide the application of a ginger and cypress nourishing composition in the preparation of cosmetics with hair nourishing, moisturizing, anti-hair loss and / or hair strengthening effects.
[0018] The embodiments of this application employing the above-described technical solution may have the following advantages: 1. By using growth promoters, the continuous production of DHT is reduced from the source, thus reducing the gradual atrophy of hair follicles. The hair conditioning agent contains more than 50% ginger extract and arborvitae leaf extract. Ginger extract simultaneously improves microcirculation, providing the blood and oxygen supply needed for hair follicle repair. Arborvitae leaf extract activates the Wnt / β-catenin signaling pathway to initiate the transition of hair follicles from the resting phase to the growth phase. The two work synergistically to promote hair shaft thickening, increase the proportion of hair follicles in the growth phase, and reduce the number of hair follicles in the regression phase, thus achieving a synergistic effect of promoting regeneration and preventing further damage. It not only restores the function of atrophied hair follicles but also improves the situation of new hair follicles being damaged again, thereby fundamentally improving the defect of thin, soft, limp, and sparse hair. 2. The peel extract of Sapindus mukorossi possesses strong surface activity and cleansing power, effectively removing sebum, keratin, and inflammatory metabolic products from the scalp surface and hair follicle openings. Lignin, on the other hand, exhibits significant antioxidant and antibacterial activity. Sapindus mukorossi saponins remove harmful substances and inflammatory factors from the scalp surface, creating a clean growth environment for hair follicles. Lignin neutralizes free radical damage that may occur during the cleansing process through its antioxidant properties and inhibits the recombination of harmful fungi (such as Malassezia) on the exposed scalp surface after cleansing through its antibacterial effects. Lignin can form intermolecular complexes with Sapindus mukorossi saponins through hydrogen bonds, reducing the risk of excessive degreasing by free saponins on the scalp surface, thereby lessening irritation to the scalp barrier. Simultaneously, lignin can form a deposition film on the hair shaft surface, increasing hair diameter and firmness, achieving a physical volume effect. Sapindus mukorossi saponins effectively remove accumulated sebum and keratin from the hair follicle openings, unclogging the hair follicle microenvironment. Through complementary pathways of gentle cleansing and physical thickening, both work synergistically to protect hair. 3. The fully acetylated green tea extract in this hair-strengthening product enhances lipid solubility, effectively penetrating the stratum corneum and accumulating in the pilosebaceous unit. By inhibiting the activity of matrix metalloproteinases (MMP-2 / 9), it reduces collagen degradation and maintains the integrity of the hair follicle basement membrane, thereby reducing abnormal hair loss during the growth phase. Gallic acid catechin gallate can improve micro-inflammation of the hair follicle caused by seborrheic alopecia through its anti-inflammatory and antioxidant effects. At the same time, its pyrogallol structure can chelate transition metal ions in the formula, inhibiting the oxidation cascade reaction and protecting active ingredients such as ginger extract and sterols from oxidation. The combination of these two ingredients can achieve a synergistic hair-strengthening effect of transdermal protection and antioxidant stabilization. Detailed Implementation
[0019] The embodiments of this application are described in detail below. It should be noted that, unless otherwise specified, the embodiments and features in the embodiments of this application can be combined with each other.
[0020] It should be understood that when an element or layer is referred to as "on," "adjacent to," "connected to," or "coupled to" other elements or layers, it may be directly on, adjacent to, connected to, or coupled to other elements or layers, or there may be intervening elements or layers. Conversely, when an element is referred to as "directly on," "directly adjacent to," "directly connected to," or "directly coupled to" other elements or layers, there are no intervening elements or layers. It should be understood that although the terms first, second, third, etc., may be used to describe various elements, components, areas, layers, and / or portions, these elements, components, areas, layers, and / or portions should not be limited by these terms. These terms are only used to distinguish one element, component, area, layer, or portion from another element, component, area, layer, or portion. Therefore, without departing from the teachings of this disclosure, the first element, component, area, layer, or portion discussed below may be referred to as a second element, component, area, layer, or portion. And the discussion of a second element, component, area, layer, or portion does not imply that the first element, component, area, layer, or portion necessarily exists in this application.
[0021] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.
[0022] It should be noted that the terms "first," "second," etc., used in the specification and claims of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such terms can be used interchangeably where appropriate so that the embodiments of this application described herein can be implemented, for example, in orders other than those described. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.
[0023] In this application, when numerical intervals (i.e., numerical ranges) are involved, unless otherwise specified, the distribution of selectable numerical values within the numerical interval is considered continuous, and includes the two endpoints of the numerical interval (i.e., the minimum and maximum values), as well as every numerical value between these two endpoints. Unless otherwise specified, when a numerical interval refers only to integers within that numerical interval, it includes the two endpoint integers of the numerical range, as well as every integer between the two endpoints, which is equivalent to directly listing every integer. When multiple numerical ranges are provided to describe features or characteristics, these numerical ranges can be merged. In other words, unless otherwise specified, the numerical ranges disclosed in this application should be understood to include any and all subranges included therein. The "numerical value" in the numerical interval can be any quantitative value, such as a number, percentage, ratio, etc. The term "numerical interval" can be broadly included to include percentage intervals, ratio intervals, proportion intervals, etc.
[0024] Exemplary embodiments according to this application will now be described in more detail. It should be understood that these exemplary embodiments may be implemented in many different forms and should not be construed as being limited to the embodiments set forth herein.
[0025] In a first aspect, embodiments of this application provide a ginger and cypress nourishing composition. This ginger and cypress nourishing composition may include the following raw materials in parts by weight: Use 5.05~11.95 parts of hair conditioner; Moisturizer 1.5~5.5 parts; Growth agent 0.5~15 parts; Anti-hair loss agent: 0.6-8 parts; Hair-strengthening agent: 0.02~1 part; Repair agent 0.8~10 parts; 0.5-5 parts of regulator; 50.75~60.25 parts of deionized water; The hair conditioning agent is a combination of arborvitae leaf extract, Polygonum multiflorum root extract, Angelica sinensis extract, ginseng root extract, Anemarrhena asphodeloides root extract, and ginger extract; and the total weight of ginger extract and arborvitae leaf extract accounts for more than 50% of the total weight of the hair conditioning agent. The growth agent is one or more of the following: β-sitosterol, sargassum sterol, saw palmetto extract, and neophytadiene modified solution.
[0026] In this embodiment, the growth agent reduces the continuous production of DHT from the source, thus reducing the gradual atrophy of hair follicles. The ginger extract and arborvitae leaf extract in the hair conditioning agent account for more than 50%. The ginger extract simultaneously improves microcirculation, providing the blood and oxygen supply needed for hair follicle repair, while the arborvitae leaf extract activates the Wnt / β-catenin signaling pathway to initiate the transition of hair follicles from the resting phase to the growth phase. The two work synergistically to promote hair shaft thickening, increase the proportion of hair follicles in the growth phase, and reduce the number of hair follicles in the regression phase, thus achieving a synergistic effect of promoting regeneration and preventing further damage. This not only restores the function of atrophied hair follicles but also improves the situation of newly formed hair follicles being damaged again, thereby fundamentally improving the defect of thin, soft, limp, and sparse hair.
[0027] It should be noted that the pathological essence of thin, soft, sparse hair is not caused by a single factor, but by a triple vicious cycle of hair follicle miniaturization: ① Androgen damage—Type II 5α-reductase in the dermal papilla cells of the hair follicle converts testosterone into dihydrotestosterone. After dihydrotestosterone binds to androgen receptors, it inhibits key signaling pathways such as Wnt / β-catenin, forcing the hair follicle to prematurely enter the regression phase from the anagen phase, resulting in a gradual thinning of the hair shaft diameter and gradual atrophy of the hair follicle; ② Microcirculatory disturbance—Atrophy of the capillary network in the scalp and insufficient blood perfusion reduce the supply of oxygen and nutrients required by the hair follicle, and hinder the energy metabolism of the dermal papilla cells; ③ Functional dormancy of hair follicle stem cells—The stem cells in the hair follicle protuberance area have a declining ability to proliferate and differentiate due to oxidative stress and the inflammatory microenvironment.
[0028] In the embodiments of this application, Platycladus orientalis leaf extract can regulate the hair follicle microenvironment by activating signaling pathways such as Akt / GSK3β and Wnt / β-catenin, promoting dermal papilla cell function and initiating the hair follicle growth phase; Angelica sinensis extract has the effect of inhibiting 5α-reductase, which can improve scalp blood microcirculation and enhance hair follicle cell activity; Ginseng root extract can promote dermal papilla cell proliferation and activate related metabolic pathways; Polygonum multiflorum root extract has antioxidant and anti-inflammatory activities and can exert hair growth effects by promoting Wnt / β-catenin signal transduction; Anemarrhena asphodeloides root extract can promote hair follicle growth, inhibit 5α-reductase activity, and regulate scalp sebum secretion; gingerol, gingerene oil, and other components in ginger extract can normalize scalp blood circulation, promote scalp metabolism, and activate hair follicle tissue. The combination of six extracts not only directly promotes hair follicles to enter the growth phase by activating hair growth signaling pathways such as Wnt / β-catenin, but also reduces the attack of DHT on hair follicles by inhibiting 5α-reductase, and provides sufficient blood and oxygen supply to hair follicles by improving scalp microcirculation, thus achieving multi-target intervention for the problem of thinning, limp, and drooping hair. Because the total weight of ginger extract and arborvitae leaf extract accounts for more than 50% of the total weight of the hair conditioning agent, it is necessary to ensure that the composition has sufficient microcirculation improvement and hair follicle activation capabilities, thereby providing a basic platform for the other auxiliary ingredients to exert their effects. This achieves a three-level synergistic effect between the hair conditioning agent and the growth agent: improving the microenvironment, blocking the source of damage, and activating regeneration capabilities. The angelica and ginger extracts in the hair conditioner improve scalp microcirculation and deliver nutrients to hair follicles; the growth agent inhibits DHT production at its source, reducing the gradual atrophy of hair follicles; and the extracts of arborvitae leaf, ginseng, and fleeceflower root in the hair conditioner activate signaling pathways such as Wnt / β-catenin, promote dermal papilla cell proliferation, and initiate the hair follicle growth phase. These three components work synergistically and are indispensable—without the growth agent blocking DHT, the hair follicles activated by the hair conditioner will continue to be attacked by androgens and atrophy again; without the hair conditioner improving microcirculation and activating hair follicles, simply inhibiting DHT cannot repair the already damaged hair follicle function.
[0029] Furthermore, many people nowadays have gray hair at a young age, commonly known as premature graying. Hair color depends on the functional state of melanocyte stem cells within the hair follicle. When these stem cells receive signals, they differentiate into mature melanocytes, which then produce melanin, giving hair color. The core mechanism of gray hair formation lies in the movement of melanocyte stem cells between different areas of the hair follicle. When they are "trapped" in the bulge area of the hair follicle, the WNT signal in this area is extremely weak, preventing the melanocyte stem cells from maturing and differentiating to produce melanin, leading to gray hair. The Wnt / β-catenin signaling pathway is a key pathway regulating the proliferation, differentiation, and pigment formation of melanocyte stem cells. When Wnt signaling is active, cells differentiate and produce pigment; when the signal weakens, cells lose the ability to produce pigment. In this embodiment, the extracts of Platycladus orientalis leaves and Polygonum multiflorum root mainly promote the differentiation of melanocyte stem cells and the production of melanin by upregulating tyrosinase activity and activating the Wnt / β-catenin signaling pathway. The two work synergistically to directly promote melanin synthesis and create a favorable nutritional microenvironment for the hair follicle. Therefore, this application also has the effect of gradually turning gray hair back to black hair.
[0030] In optional embodiments, the repair agent includes one or more combinations of Sapindus mukorossi peel extract, milk thistle seed extract, and nicotinamide.
[0031] In this embodiment, individuals with fine, limp hair often experience scalp oil imbalances and frequent oily cleansing, leading to damage to the scalp's keratin barrier and decreased permeability around the hair follicles. This prevents active nutrients from reaching the hair papilla. Sapindus mukorossi peel extract, containing natural saponins, gently metabolizes dead skin cells at the hair follicle opening, clearing blockages and repairing gaps in the scalp's epidermal keratin layer. Milk thistle seed extract, rich in silymarin, specifically eliminates scalp free radicals, reducing follicle oxidation and apoptosis caused by UV rays and external stimuli, thus lowering the probability of hair breakage. Niacinamide regulates scalp ceramide synthesis, thickens the scalp barrier, reduces the probability of scalp inflammation recurrence, and increases the synthesis of keratin in the hair shaft, filling gaps in the cuticles of fine, limp hair and improving hair stiffness. These three components comprehensively repair damaged hair and follicles from three levels: purifying the hair growth environment, repairing the hair shaft structure, and protecting hair follicle cells.
[0032] In optional embodiments, the regulator includes one or more combinations of lignin, chitin, chitosan, sophorolipid, and microfibrillated cellulose.
[0033] In this embodiment, the regulator has a triple function of emulsification and cross-linking, charge adsorption, and physical support. Chitosan and chitin carry cationic charges, which can adsorb anionic hair cuticles, strengthen the anchoring bond between hair roots and scalp epidermis, and reduce hair slippage and loss. Lignin and microfibrillated cellulose can construct a three-dimensional network colloidal structure, stabilize the oil-water two-phase system of the formula, lock in the heat-sensitive active ingredients of ginger and arborvitae leaves, and avoid active degradation caused by high-temperature preparation processes. Sophorolipids are biological surfactants that synergistically optimize scalp surface tension, making hair roots stand up and fluffy, and improving the problem of limp and flat hair strands. In addition, the regulator of this application has no scalp occlusion and will not clog fine and soft hair follicles, improving the overall stability of the formula, and also has a physical hair-strengthening and fluffing effect, effectively improving the phenomenon of fine and limp hair.
[0034] In an optional embodiment, when the repair agent is Sapindus mukorossi pericarp extract, the regulator is lignin, and the weight ratio of Sapindus mukorossi pericarp extract to lignin is 1:(0.1~0.8).
[0035] In this embodiment, the extract of Sapindus mukorossi fruit peel has strong surface activity and detergency, effectively removing sebum, keratin, and inflammatory metabolites from the scalp surface and hair follicle openings. Lignin, on the other hand, exhibits significant antioxidant and antibacterial activity. Sapindus mukorossi saponins remove harmful substances and inflammatory factors from the scalp surface, creating a clean growth environment for hair follicles. Lignin neutralizes free radical damage that may occur during the removal process through its antioxidant effect and inhibits the recombination of harmful fungi (such as Malassezia) on the exposed scalp surface after removal through its antibacterial effect. Lignin can form intermolecular complexes with Sapindus mukorossi saponins through hydrogen bonds, reducing the risk of excessive degreasing by free saponins on the scalp surface, thereby mitigating irritation to the scalp barrier. Simultaneously, lignin can form a deposition film on the hair shaft surface, increasing hair diameter and firmness, achieving a physical volume effect. Sapindus mukorossi saponins effectively remove accumulated sebum and keratin from the hair follicle openings, unclogging the hair follicle microenvironment. Through complementary pathways of gentle cleansing and physical thickening, both work synergistically to protect hair. When the weight ratio of soapberry peel extract to lignin is 1:(0.1~0.8), both cleansing efficacy and hair sensory experience can be achieved.
[0036] In optional embodiments, the hair-fixing agent comprises one or a combination of two of gallic acid catechin gallate and fully acetylated green tea extract.
[0037] In this embodiment, the fully acetylated green tea extract in the hair-fixing agent enhances lipid solubility, effectively penetrates the stratum corneum, and accumulates in the pilosebaceous unit. By inhibiting the activity of matrix metalloproteinases (MMP-2 / 9), it reduces collagen degradation and maintains the integrity of the hair follicle basement membrane structure, thereby reducing abnormal hair loss during the growth phase. Gallic acid catechin gallate can improve micro-inflammation of hair follicles caused by seborrheic alopecia through anti-inflammatory and antioxidant effects. At the same time, its pyrogallol structure can chelate transition metal ions in the formula, inhibit oxidation cascade reactions, and protect active ingredients such as ginger extract and sterols from oxidation. The combination of the two can achieve a synergistic hair-fixing effect of transdermal protection and antioxidant stabilization.
[0038] In an optional embodiment, the preparation method of the neophytadiene modified solution is as follows: neophytadiene is dissolved in a solubilizer and mixed evenly to form a neophytadiene modified solution; wherein, the weight ratio of neophytadiene to solubilizer is 1:(3~10); the solubilizer includes one or more combinations of PEG-40 hydrogenated castor oil, polysorbate-80 and oleyl alcohol polyether-20.
[0039] In this embodiment, neophytadiene suffers from poor solubility and low transdermal absorption. By dissolving neophytadiene in solubilizers such as PEG-40 hydrogenated castor oil, polysorbate-80, or oleyl alcohol polyether-20, a modified neophytadiene solution is formed. The solubilizer, through its amphiphilic molecular structure, encapsulates the hydrophobic neophytadiene within a micelle core, forming a nanoscale drug delivery system with good water dispersibility. When the weight ratio of neophytadiene to solubilizer is less than 1:3, a stable micelle encapsulation structure cannot be formed, and neophytadiene easily precipitates in the aqueous phase, making effective delivery to the hair follicle difficult. When the weight ratio of neophytadiene to solubilizer is greater than 1:10, the proportion of solubilizer in the system is too large, diluting the effective concentration of neophytadiene and reducing its efficacy per unit dose. Therefore, a weight ratio of neophytadiene to solubilizer within the range of 1:(3~10) ensures sufficient dissolution, stable dispersion, and effective delivery of neophytadiene in the composition, thereby guaranteeing its targeted delivery to the hair follicle and its bioavailability.
[0040] In optional embodiments, the anti-shedding agent includes one or a combination of two of the following: enzyme-converted Sophora flavescens extract and Lactobacillus soymilk fermentation product.
[0041] In this embodiment, the enzyme-converted Sophora flavescens extract is enzymatically hydrolyzed and enriched with Sophora flavescens flavonoids, which target and inhibit the proliferation of harmful bacteria on the scalp, downregulate scalp inflammatory mediators, and reduce follicular atrophy caused by inflammation. The fermentation product of Lactobacillus soybaby contains small molecule metabolic peptides and organic acids, which reshape the homeostasis of beneficial bacteria on the scalp, repair the scalp immune microenvironment, and reduce the expression of telogen effluvium inducing factors. The enzyme-converted Sophora flavescens extract and the fermentation product of Lactobacillus soybaby work synergistically. On the one hand, the enzyme-converted Sophora flavescens extract upregulates insulin-like growth factor-1 (IGF-1) and keratinocyte proliferation... The expression of growth factor (KGF) stimulates the transformation of hair follicles from the resting phase to the growth phase and significantly inhibits 5α-reductase activity to reduce the damage of dihydrotestosterone (DHT) to hair follicles, thus activating hair growth from the source. On the other hand, fermented products of Lactobacillus soybaby regulate the scalp microecology, inhibit the excessive proliferation of harmful bacteria such as Malassezia, and provide small molecule nutrients such as amino acids and peptides, creating a healthy growth environment for hair follicles. Therefore, the combination of the two can not only stop the hair loss process but also strengthen the hair roots, effectively achieving the synergistic effect of preventing hair loss and strengthening hair.
[0042] In an optional embodiment, the humectant is butylene glycol, 1,2-hexanediol and octyl glycol, and the weight ratio of butylene glycol, 1,2-hexanediol and octyl glycol is (34~36):(0.35~0.65):(0.35~0.65).
[0043] In this embodiment, butylene glycol is the main moisturizing ingredient, providing basic moisturizing capabilities; 1,2-hexanediol and caprylyl glycol have both moisturizing and antiseptic synergistic functions. When the weight ratio of butylene glycol, 1,2-hexanediol and caprylyl glycol is in the range of (34~36):(0.35~0.65):(0.35~0.65), butylene glycol, being the absolute majority, provides sufficient hydration, while 1,2-hexanediol and caprylyl glycol, existing in trace amounts, can synergistically enhance the moisturizing network and also play their auxiliary antiseptic role.
[0044] Secondly, this application also provides a method for preparing the ginger and cypress nourishing composition of any of the above embodiments, comprising the following steps: S1: Weigh out the corresponding hair conditioning agent and moisturizer according to the weight parts, stir and disperse them at room temperature until there are no particles, then put them into deionized water, stir at 40~60℃ until completely dissolved and transparent, keep warm for later use, and obtain an aqueous phase mixture. S2: Weigh the corresponding growth agent into a container according to the weight parts and stir evenly at 50~70℃ to obtain an oil phase mixture; S3: Under stirring conditions, slowly add the oil phase mixture obtained in step S2 to the aqueous phase mixture obtained in step S1, then homogenize and emulsify for 10-30 minutes, then cool to 35-45℃, then add the anti-hair loss agent and repair agent and stir for 5-10 minutes, then add the hair-fixing agent and stir in the dark for 8-15 minutes, finally add the regulator and stir until completely dispersed and without lumps, then discharge the material after stirring evenly to obtain the ginger and cypress nourishing composition.
[0045] In this embodiment, step S1 employs low-temperature dispersion and constant-temperature dissolution at 40-60℃. Low-temperature dissolution protects the thermosensitive polyphenols of Platycladus orientalis and ginger from degradation, pre-disperses the conditioning agent and moisturizer, and pre-opens the nutrient channels in the aqueous phase. In step S2, the oil phase growth agent is dissolved at a controlled temperature of 50-70℃ to avoid high-temperature damage to the growth agent's proliferation activity. In step S3, the material is added in stages with gradient cooling. Anti-hair loss and repair agents are added at a medium temperature of 35-45℃ to match the bioactivity of fermentation products and enzymatic extracts. Hair-strengthening agents are added at low temperature and away from light to prevent discoloration and inactivation. Finally, a regulator is added for dispersion to reduce the possibility of premature polymer aggregation and cross-linking, which can lead to a particulate feel and poor permeability in the system. The entire process of this embodiment is temperature-controlled and time-series coupled with the active characteristics of the raw materials to maximize the retention of the efficacy of each component.
[0046] Thirdly, the embodiments of this application also provide the application of the ginger and cypress nourishing composition of any of the above embodiments in the preparation of cosmetics with hair nourishing, hair moisturizing, hair loss prevention and / or hair strengthening effects.
[0047] In this embodiment, the composition of this application relies on the aforementioned synergistic mechanism of the components and can be stably applied to the preparation of hair care cosmetics such as hair nourishing, hair conditioning, hair loss prevention, and hair strengthening. It can effectively improve technical problems such as excessive scalp oil secretion, prolonged resting phase of hair follicles, miniaturization of hair follicles, thin hair strands, weak hair root anchoring force, and flat and limp hair strands.
[0048] The following specific embodiments provide a more detailed description of this application, but should not be construed as limiting the application. Any modifications or substitutions made to the methods, steps, or conditions of this application without departing from the spirit and substance of this application are within the scope of this application.
[0049]
Example 1
[0050] Example 2 - Example 7 In Example 2, the preparation method of a ginger and cypress nourishing composition differs from that in Example 1 in that the growth agent in S2 is 6 parts of β-sitosterol, the anti-shedding agent in S3 is 4.3 parts of fermentation product of Lactobacillus sacchariformis, and the regulator is 1.6 parts of lignin and 1.6 parts of microfibrillated cellulose.
[0051] In Example 3, the preparation method of a ginger and cypress nourishing composition differs from that in Example 1 in that the growth agent in S2 is 6 parts of a neophyte-modified solution. The preparation method of the neophyte-modified solution is as follows: neophyte and solubilizer PEG-40 hydrogenated castor oil are mixed evenly in a weight ratio of 1:5 to form a neophyte-modified solution.
[0052] In Example 4, the preparation method of a ginger and cypress nourishing composition differs from that in Example 1 in that the growth agent in S2 is 10 parts of a new phytadiene modified solution. The preparation method of the new phytadiene modified solution is as follows: new phytadiene and solubilizer polysorbate-80 are mixed evenly in a weight ratio of 1:3 to form a new phytadiene modified solution.
[0053] In Example 5, the preparation method of a ginger and cypress nourishing composition differs from that in Example 1 in that the growth agent in S2 is 4 parts of β-sitosterol, 2 parts of sargassum sterol, and 4 parts of saw palmetto extract.
[0054] In Example 6, the preparation method of a ginger and cypress nourishing composition differs from that in Example 1 in that the repair agent in S3 is 3 parts milk thistle seed extract and nicotinamide, and the regulator is 1.6 parts chitosan.
[0055] In Example 7, the preparation method of a ginger and cypress nourishing composition differs from that in Example 1 in that the hair-fixing agent in S3 is 0.1 parts of fully acetylated green tea extract.
[0056] Comparative Examples 1-6 The difference between Comparative Example 1 and Example 1 is that no growth agent, anti-hair loss agent, hair strengthening agent, repair agent and regulator were added in Comparative Example 1.
[0057] The difference between Comparative Example 2 and Example 1 is that no growth agent was added in Comparative Example 1.
[0058] The difference between Comparative Example 3 and Example 1 is that no anti-shedding agent was added in Comparative Example 1.
[0059] The difference between Comparative Example 4 and Example 1 is that no hair-fixing agent was added in Comparative Example 1.
[0060] In Comparative Example 5, the difference from Example 1 is that no repair agent was added in Comparative Example 1.
[0061] The difference between Comparative Example 6 and Example 1 is that no regulator was added in Comparative Example 1.
[0062]
Application Example
[0063] Application Example 2: A shampoo prepared using the ginger and cypress nourishing composition from Example 2.
[0064] Application Example 3: A shampoo prepared using the ginger and cypress nourishing composition from Example 3.
[0065] Application Example 4: A shampoo prepared using the ginger and cypress nourishing composition from Example 4.
[0066] Application Example 5: A shampoo prepared using the ginger and cypress nourishing composition from Example 5.
[0067] Application Example 6: A shampoo prepared using the ginger and cypress nourishing composition from Example 6.
[0068] Application Example 7: A shampoo prepared using the ginger and cypress nourishing composition from Example 7.
[0069]
Comparative Application Examples
[0070] Compared with Application Example 2, a shampoo prepared using the ginger and cypress nourishing composition from Comparative Example 2 was used.
[0071] Compared with Application Example 3, a shampoo prepared using the ginger and cypress nourishing composition from Comparative Example 3 was used.
[0072] Compared with Application Example 4, a shampoo was prepared using the ginger and cypress nourishing composition from Comparative Example 4.
[0073] Compared with Application Example 5, a shampoo was prepared using the ginger and cypress nourishing composition from Comparative Example 5.
[0074] Compared with Application Example 6, a shampoo prepared using the ginger and cypress nourishing composition from Comparative Example 6 was used.
[0075] The following performance tests were conducted on the shampoos provided in Application Examples 1-7 and Comparative Application Examples 1-6 of this application to obtain corresponding test data on non-irritation, fine and limp hair, anti-hair loss, dandruff removal and anti-itch, and oil control. The performance test results are as follows: Experimental grouping: Individuals aged 25-40 with hair breakage, hair loss, thinning hair, gray hair, and fine, limp hair were selected as test subjects and randomly divided into 13 groups of 10 people each. There were no significant differences among the groups in terms of age and the degree of hair breakage, hair loss, thinning hair, and fine, limp hair, making them comparable. Groups 1-7 used the shampoos from Examples 1-7, respectively, while groups 8-13 used the shampoos from Examples 1-6 as a control.
[0076] How to use shampoo: After wetting your hair, take an appropriate amount of shampoo, lather it up, apply it evenly to your hair, and then massage it in circular motions with your fingertips from the roots to the ends for 5 minutes. Then rinse it thoroughly with water.
[0077] Test results: A public opinion poll scoring method was used for comprehensive evaluation. Each group washed their hair every two days for three consecutive months and immediately filled out a trial evaluation form. The total score for each item on the evaluation form is 5 points, with 5 being the highest score, indicating very satisfied; 4 being good, indicating relatively satisfied; 3 being acceptable; and below 3 being unacceptable. The average scores for each item are shown in Table 1. Table 1: Test data of application examples 1-7 and comparative application examples 1-6 of a ginger and cypress nourishing shampoo. As shown in Table 1, there was little difference between the shampoos used in Examples 1-7 and the control examples 1-6 in terms of the non-irritant index. However, in terms of improving fine, limp, and thinning hair, improving hair loss, improving dandruff and itch relief, and improving oil control, Examples 1-7 showed a significant improvement over the control examples 1-6. Examples 1-7 demonstrated a substantial improvement in these areas.
[0078] By comparing Application Example 1 and Comparative Application Examples 1-6, it can be seen that in the core indicator of improvement in fine, soft, sparse hair, the combined use of growth regulators and regulators has a significant effect on improving fine, soft, sparse hair. This is achieved through a dual pathway of hormone regulation and physical fluffing to improve the condition of fine, soft, sparse hair.
[0079] By comparing application example 1 and comparative application examples 1-6, it can be seen that in the indicator of hair loss improvement, the combined use of growth agents and anti-hair loss agents is essential. Growth agents inhibit DHT production from the source of hormones, while anti-hair loss agents work together to prevent hair loss from two levels: hair follicle activation and microecological regulation. Both are indispensable, and their combination greatly improves the hair loss phenomenon.
[0080] It should be noted that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential," etc., are used only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application. The directional terms "inner" and "outer" refer to the inside or outside relative to the outline of each component itself. Thus, the exemplary term "above" can include both "above" and "below." The device may also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatial relative descriptions used herein are interpreted accordingly.
[0081] It should also be noted that the terms "one embodiment," "another embodiment," and "embodiment" used in this application refer to specific features, structures, or characteristics described in connection with that embodiment, which are included in at least one embodiment described in the general description of this application. The appearance of the same expression in multiple places in the specification does not necessarily refer to the same embodiment. Furthermore, when a specific feature, structure, or characteristic is described in connection with any embodiment, the intention is to suggest that implementing such a feature, structure, or characteristic in conjunction with other embodiments also falls within the scope of this application.
[0082] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.
[0083] It should also be noted that the above are merely preferred embodiments of this application and do not limit the scope of patent protection of this application. Any equivalent structural or procedural changes made using the content of this application's specification, or any direct or indirect application in other related technical fields, are similarly included within the scope of patent protection of this application.
Claims
1. A composition for nourishing and moisturizing with ginger and cypress, characterized in that, Including the following parts by weight of raw materials: Use 5.05~11.95 parts of hair conditioner; Moisturizer 1.5~5.5 parts; Growth agent 0.5~15 parts; Anti-hair loss agent: 0.6-8 parts; Hair-strengthening agent: 0.02~1 part; Repair agent 0.8~10 parts; 0.5-5 parts of regulator; 50.75~60.25 parts of deionized water; The hair conditioning agent is a combination of Platycladus orientalis leaf extract, Polygonum multiflorum root extract, Angelica sinensis extract, ginseng root extract, Anemarrhena asphodeloides root extract, and ginger extract; and the total weight of the ginger extract and the Platycladus orientalis leaf extract accounts for more than 50% of the total weight of the hair conditioning agent. The growth agent is one or more of the following: β-sitosterol, sargassum sterol, saw palmetto extract, and neophytadiene modified solution.
2. The ginger and cypress nourishing composition according to claim 1, characterized in that, The repair agent includes one or more of the following: Sapindus mukorossi peel extract, milk thistle seed extract, and nicotinamide.
3. The ginger and cypress nourishing composition according to claim 2, characterized in that, The regulator includes one or more of lignin, chitin, chitosan, sophorolipid, and microfibrillated cellulose.
4. The ginger and cypress nourishing composition according to claim 3, characterized in that, When the repair agent is Sapindus mukorossi fruit peel extract, the regulator is lignin, and the weight ratio of Sapindus mukorossi fruit peel extract to lignin is 1:(0.1~0.8).
5. The ginger and cypress nourishing composition according to claim 1, characterized in that, The hair-strengthening agent comprises one or a combination of two of gallic acid catechin gallate and fully acetylated green tea extract.
6. The ginger and cypress nourishing composition according to claim 1, characterized in that, The preparation method of the neophytadiene modified solution is as follows: Neophytadiene is dissolved in a solubilizer and mixed evenly to form a neophytadiene modified solution; The weight ratio of the neophytadiene to the solubilizer is 1:(3~10); the solubilizer includes one or more of PEG-40 hydrogenated castor oil, polysorbate-80 and oleyl alcohol polyether-20.
7. The ginger and cypress nourishing composition according to claim 1, characterized in that, The anti-hair loss agent includes one or a combination of two of the following: enzyme-converted Sophora flavescens extract and fermentation product of Lactobacillus soyba.
8. The ginger and cypress nourishing composition according to claim 1, characterized in that, The humectant is butylene glycol, 1,2-hexanediol and octyl glycol, and the weight ratio of butylene glycol, 1,2-hexanediol and octyl glycol is (34~36):(0.35~0.65):(0.35~0.65).
9. A method for preparing the ginger and cypress nourishing composition according to any one of claims 1 to 8, characterized in that, Includes the following steps: S1: Weigh out the corresponding hair conditioning agent and moisturizer according to the weight parts, stir and disperse them at room temperature until there are no particles, then put them into deionized water, stir at 40~60℃ until completely dissolved and transparent, keep warm for later use, and obtain an aqueous phase mixture. S2: Weigh the corresponding growth agent into a container according to the weight parts and stir evenly at 50~70℃ to obtain an oil phase mixture; S3: Under stirring conditions, slowly add the oil phase mixture obtained in step S2 to the aqueous phase mixture obtained in step S1, then homogenize and emulsify for 10-30 minutes, then cool to 35-45℃, then add the anti-hair loss agent and repair agent and stir for 5-10 minutes, then add the hair-fixing agent and stir in the dark for 8-15 minutes, finally add the regulator and stir until completely dispersed and without lumps, then discharge the material after stirring evenly to obtain the ginger and cypress nourishing composition.
10. The use of the ginger and cypress nourishing composition according to any one of claims 1-8 in the preparation of cosmetics with hair nourishing, moisturizing, anti-hair loss and / or hair strengthening effects.