A traditional Chinese medicine composition for treating rheumatoid arthritis and / or low back pain

Abstract

This invention provides a traditional Chinese medicine composition for rheumatoid arthritis and / or low back pain and its medicinal uses. The traditional Chinese medicine composition of this invention comprises the following raw materials in parts by weight: Angelica sinensis 6-15 parts, Ligusticum chuanxiong 6-10 parts, Rehmannia glutinosa 3-12 parts, Paeonia lactiflora 6-20 parts, Adenophora stricta 6-15 parts, Saposhnikovia divaricata 6-15 parts, Bupleurum chinense 3-15 parts, Scutellaria baicalensis 6-12 parts, Astragalus membranaceus 10-50 parts, Polygonatum sibiricum 6-20 parts, Paeonia suffruticosa 6-20 parts, Gentiana macrophylla 6-20 parts, Dipsacus asper 6-20 parts, Sargentodoxa cuneata 6-20 parts, Taxillus chinensis 6-16 parts, Polygonatum odoratum 6-20 parts, Ophiopogon japonicus 6-20 parts, Drynaria fortunei 10-15 parts, Achyranthes bidentata 6-20 parts, Alisma plantago-aquatica 10-30 parts, Ziziphus jujuba var. spinosa (fried) 10-50 parts, Magnolia officinalis 6-15 parts, Peucedanum praeruptorum 3-12 parts, and Boswellia carterii 3-9 parts. This invention also provides a medicine prepared from the aforementioned traditional Chinese medicine composition. The traditional Chinese medicine composition described in this invention has the dual effects of strengthening the body's resistance and eliminating pathogenic factors. It can improve joint swelling, pain, and stiffness in rheumatoid arthritis, relieve various types of lower back pain, and regulate the body's constitution. The medicinal properties are mild and suitable for the treatment of chronic diseases.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine, specifically relating to a traditional Chinese medicine composition and its medicinal use in treating rheumatoid arthritis and / or lower back pain. Background Technology

[0002] Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory disease of unknown etiology. It is an autoimmune disease characterized by erosive arthritis as its main clinical manifestation. Joint lesions are characterized by symmetry, progression, and destruction, primarily affecting peripheral joints. Symptoms include chronic swelling, pain, morning stiffness, and functional impairment, gradually leading to the destruction of articular cartilage and bone, ultimately resulting in joint deformities and loss of function. The global prevalence of rheumatoid arthritis is approximately 0.24% to 1%. Lower back pain is a symptom of pain located in the lower back, extending from the ribcage to the hip crease, and is mostly related to the musculoskeletal system. Clinically, both rheumatoid arthritis and lower back pain are often persistent and difficult to cure. In modern medicine, rheumatoid arthritis and lower back pain are considered two different diseases. However, in traditional Chinese medicine theory, the two share a common pathogenesis: rheumatoid arthritis belongs to the category of "Bi syndrome" in TCM, caused by deficiency of liver and kidney, resulting in malnourishment of tendons and bones, making them susceptible to invasion by external pathogens and leading to joint diseases; while the waist is the "residence of the kidneys," and deficiency of kidney essence or insufficient kidney yang leads to malnourishment of the waist, making it susceptible to invasion by external pathogens, inducing or aggravating lower back pain. Therefore, the core pathogenesis of rheumatoid arthritis and lower back pain is deficiency of the root cause and excess of the branch, with deficiency of vital energy (especially deficiency of liver and kidney) as the root cause, and invasion of external pathogens and internal accumulation of pathogenic factors (such as phlegm and blood stasis) as the branch causes. Therefore, under the guidance of TCM theory, rheumatoid arthritis and lower back pain can be treated "different diseases with the same method." For example, the Du Huo Ji Sheng Tang, composed of 15 herbs including Angelica pubescens, Taxillus chinensis, Eucommia ulmoides, Achyranthes bidentata, Asarum heterotropoides, Gentiana macrophylla, Poria cocos, Cinnamomum cassia, Saposhnikovia divaricata, Ligusticum chuanxiong, Panax ginseng, Glycyrrhiza uralensis, Angelica sinensis, Paeonia lactiflora, and Rehmannia glutinosa, can be used for patients with rheumatoid arthritis and / or lower back pain who are diagnosed by traditional Chinese medicine as having liver and kidney deficiency and wind-cold-dampness syndrome.

[0003] According to data from the 2019 Global Burden of Disease Study cited by the World Health Organization (WHO), approximately 18 million people worldwide suffer from rheumatoid arthritis (GBD 2019: Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. https: / / vizhub.healthdata.org / gbd-results / ). Meanwhile, low back pain remains a significant public health issue affecting hundreds of millions of people globally. Therefore, there remains an unmet need for treatment of rheumatoid arthritis and / or low back pain. Summary of the Invention

[0004] To address the problems existing in the prior art, this invention provides a traditional Chinese medicine composition that targets the core pathogenesis of rheumatoid arthritis and low back pain. The composition follows the treatment principles of "tonifying qi and blood, nourishing the liver and kidneys, dispelling wind and dampness, and unblocking the meridians." It employs a rigorous combination of principal, assistant, and adjuvant herbs, combining both warming and cooling herbs, and balancing the strengthening of the body's resistance with the elimination of pathogenic factors. This composition has a clear therapeutic effect on various types of rheumatoid arthritis and musculoskeletal related low back pain.

[0005] Therefore, in a first aspect, the present invention provides a traditional Chinese medicine composition for rheumatoid arthritis and / or low back pain, comprising the following raw materials in parts by weight:

[0006] Angelica sinensis 6-15 parts, Ligusticum chuanxiong 6-10 parts, Rehmannia glutinosa 3-12 parts, Paeonia lactiflora 6-20 parts, Adenophora stricta 6-15 parts, Saposhnikovia divaricata 6-15 parts, Bupleurum chinense 3-15 parts, Scutellaria baicalensis 6-12 parts, Astragalus membranaceus 10-50 parts, Polygonatum sibiricum 6-20 parts, Paeonia suffruticosa 6-20 parts, Gentiana macrophylla 6-20 parts, Dipsacus asper 6-20 parts, Sargentodoxa cuneata 6-20 parts, Taxillus chinensis 6-16 parts, Polygonatum odoratum 6-20 parts, Ophiopogon japonicus 6-20 parts, Drynaria fortunei 10-15 parts, Achyranthes bidentata 6-20 parts, Alisma plantago-aquatica 10-30 parts, Ziziphus jujuba var. spinosa 10-50 parts, Magnolia officinalis 6-15 parts, Peucedanum praeruptorum 3-12 parts, Boswellia carterii 3-9 parts.

[0007] Preferably, the traditional Chinese medicine composition comprises the following raw materials in parts by weight:

[0008] Angelica sinensis 8-12 parts, Ligusticum chuanxiong 8-10 parts, Rehmannia glutinosa 6-12 parts, Paeonia lactiflora 10-18 parts, Adenophora stricta 10-18 parts, Saposhnikovia divaricata 8-12 parts, Bupleurum chinense 5-12 parts, Scutellaria baicalensis 8-10 parts, Astragalus membranaceus 15-40 parts, Polygonatum sibiricum 8-18 parts, Paeonia suffruticosa 10-18 parts, Gentiana macrophylla 10-18 parts, Dipsacus asper 10-18 parts, Sargentodoxa cuneata 10-18 parts, Taxillus chinensis 8-15 parts, Polygonatum odoratum 8-18 parts, Ophiopogon japonicus 8-18 parts, Drynaria fortunei 10-14 parts, Achyranthes bidentata 10-18 parts, Alisma plantago-aquatica 12-25 parts, Ziziphus jujuba var. spinosa 15-40 parts, Magnolia officinalis 8-14 parts, Peucedanum praeruptorum 6-12 parts, Boswellia carterii 4-8 parts.

[0009] More preferably, the traditional Chinese medicine composition comprises the following raw materials in parts by weight:

[0010] Angelica sinensis 10-12 parts, Ligusticum chuanxiong 8-9 parts, Rehmannia glutinosa 8-10 parts, Paeonia lactiflora 12-15 parts, Adenophora stricta 10-12 parts, Saposhnikovia divaricata 10-12 parts, Bupleurum chinense 8-10 parts, Scutellaria baicalensis 9-10 parts, Astragalus membranaceus 20-30 parts, Polygonatum sibiricum 12-15 parts, Paeonia suffruticosa 12-15 parts, Gentiana macrophylla 12-15 parts, Dipsacus asper 12-15 parts, Sargentodoxa cuneata 12-15 parts, Taxillus chinensis 10-12 parts, Polygonatum odoratum 12-15 parts, Ophiopogon japonicus 12-15 parts, Drynaria fortunei 12-13 parts, Achyranthes bidentata 12-15 parts, Alisma plantago-aquatica 15-20 parts, Ziziphus jujuba var. spinosa 20-30 parts, Magnolia officinalis 10-12 parts, Peucedanum praeruptorum 8-10 parts, Boswellia carterii 5-7 parts.

[0011] As a particularly preferred embodiment, the present invention provides a traditional Chinese medicine composition for rheumatoid arthritis and / or low back pain, comprising the following raw materials in parts by weight:

[0012] Take 12 parts Angelica sinensis, 9 parts Ligusticum chuanxiong, 10 parts Rehmannia glutinosa, 15 parts Paeonia lactiflora, 12 parts Adenophora stricta, 12 parts Saposhnikovia divaricata, 10 parts Bupleurum chinense, 10 parts Scutellaria baicalensis, 30 parts Astragalus membranaceus, 15 parts Polygonatum sibiricum, 15 parts Paeonia suffruticosa, 15 parts Gentiana macrophylla, 15 parts Dipsacus asper, 15 parts Sargentodoxa cuneata, 12 parts Taxillus chinensis, 15 parts Polygonatum odoratum, 15 parts Ophiopogon japonicus, 12 parts Drynaria fortunei, 15 parts Achyranthes bidentata, 20 parts Alisma plantago-aquatica, 30 parts stir-fried Ziziphus jujuba var. spinosa, 12 parts Magnolia officinalis, 10 parts Peucedanum praeruptorum, and 6 parts Boswellia carterii.

[0013] A second objective of this invention is to provide the use of the above-mentioned traditional Chinese medicine composition in the preparation of a medicament for rheumatoid arthritis and / or low back pain.

[0014] Preferably, the rheumatoid arthritis includes various types of rheumatoid arthritis, including but not limited to rheumatic obstruction syndrome, cold-damp obstruction syndrome, damp-heat obstruction syndrome, phlegm-blood stasis obstruction syndrome, blood stasis obstruction syndrome, qi and blood deficiency syndrome, liver and kidney deficiency syndrome, and qi and yin deficiency syndrome.

[0015] Preferably, the lower back pain is musculoskeletal related lower back pain, selected from one or more of the following: kidney deficiency lower back pain, rheumatic obstruction lower back pain, lumbar muscle strain, and lumbar degenerative disease.

[0016] Preferably, the rheumatoid arthritis and / or low back pain are characterized by aching and pain in the limbs and joints or lower back, heaviness and stiffness, limited mobility, aggravation by exposure to wind, cold and dampness, significant exacerbation of symptoms after exertion, limited limb flexion and extension, accompanied by fatigue, shortness of breath, reluctance to speak, soreness and weakness in the lower back and knees, emotional distress, and poor sleep; the tongue is dark or has petechiae, and the tongue coating is thin white or slightly greasy; the pulse is deep and thready, deep and hesitant, or thready and slow.

[0017] A third objective of this invention is to provide a medicament for rheumatoid arthritis and / or low back pain, prepared using the traditional Chinese medicine composition described in this invention as the active ingredient.

[0018] Preferably, the traditional Chinese medicine composition is the only active ingredient of the drug.

[0019] Preferably, the rheumatoid arthritis includes various types of rheumatoid arthritis, including but not limited to rheumatic obstruction syndrome, cold-damp obstruction syndrome, damp-heat obstruction syndrome, phlegm-blood stasis obstruction syndrome, blood stasis obstruction syndrome, qi and blood deficiency syndrome, liver and kidney deficiency syndrome, and qi and yin deficiency syndrome.

[0020] Preferably, the lower back pain is musculoskeletal related lower back pain, selected from one or more of the following: kidney deficiency lower back pain, rheumatic obstruction lower back pain, lumbar muscle strain, and lumbar degenerative disease.

[0021] Preferably, the rheumatoid arthritis and / or low back pain are characterized by aching and pain in the limbs and joints or lower back, heaviness and stiffness, limited mobility, aggravation by exposure to wind, cold and dampness, significant exacerbation of symptoms after exertion, limited limb flexion and extension, accompanied by fatigue, shortness of breath, reluctance to speak, soreness and weakness in the lower back and knees, emotional distress, and poor sleep; the tongue is dark or has petechiae, and the tongue coating is thin white or slightly greasy; the pulse is deep and thready, deep and hesitant, or thready and slow.

[0022] Preferably, the drug is a clinically acceptable formulation comprising pharmaceutically acceptable excipients.

[0023] The pharmaceutically acceptable excipients include, but are not limited to: (1) diluents, such as starch, powdered sugar, dextrin, lactose, pregelatinized starch, microcrystalline fiber, inorganic calcium salts (such as calcium sulfate, calcium hydrogen phosphate, pharmaceutical calcium carbonate, etc.), mannitol, vegetable oil, polyethylene glycol, etc.; (2) binders, such as distilled water, ethanol, starch paste, sodium carboxymethyl cellulose, hydroxypropyl cellulose, methyl cellulose and ethyl cellulose, hydroxypropyl methyl cellulose, etc.; (3) disintegrants, such as dry starch, sodium carboxymethyl starch, low-substituted hydroxypropyl cellulose, croscarmellose, croscarmellose sodium, etc.; (4) lubricants, such as magnesium stearate, micronized silica gel, talc, hydrogenated vegetable oil, polyethylene glycol, magnesium lauryl sulfate, etc.

[0024] Preferably, the formulation is an oral formulation.

[0025] More preferably, the oral preparation is selected from decoctions, tablets, capsules, powders, pills, or granules.

[0026] The traditional Chinese medicine composition of this invention comprises Angelica sinensis, Ligusticum chuanxiong, Rehmannia glutinosa, Paeonia lactiflora, Adenophora stricta, Saposhnikovia divaricata, Bupleurum chinense, Scutellaria baicalensis, Astragalus membranaceus, Polygonatum sibiricum, Paeonia suffruticosa, Gentiana macrophylla, Dipsacus asper, Sargentodoxa cuneata, Taxillus chinensis, Polygonatum odoratum, Ophiopogon japonicus, Drynaria fortunei, Achyranthes bidentata, Alisma plantago-aquatica, Ziziphus jujuba var. spinosa (fried), Magnolia officinalis, Peucedanum praeruptorum, and... mastic This formula consists of twenty-four kinds of raw materials. Angelica sinensis, Astragalus membranaceus, Dipsacus asper, and Taxillus chinensis are the principal herbs. Ligusticum chuanxiong, Gentiana macrophylla, Sargentodoxa cuneata, Achyranthes bidentata, Rehmannia glutinosa, Paeonia lactiflora, Scutellaria baicalensis, Polygonatum sibiricum, Drynaria fortunei, and Peucedanum praeruptorum are the assistant herbs. Glehnia littoralis, Polygonatum odoratum, Ophiopogon japonicus, Saposhnikovia divaricata, Bupleurum chinense, Boswellia carterii, Paeonia suffruticosa, Magnolia officinalis, Alisma plantago-aquatica, and Ziziphus jujuba var. spinosa are added as adjuvant herbs. Angelica sinensis and Astragalus membranaceus invigorate qi and nourish blood; Dipsacus asper and Taxillus chinensis tonify the liver and kidneys, strengthen tendons and bones, and dispel wind and dampness. These four herbs directly target the core deficiency of the disease and are thus the principal herbs. Ligusticum chuanxiong, Gentiana macrophylla, Sargentodoxa cuneata, Achyranthes bidentata, Rehmannia glutinosa, Paeonia lactiflora, Scutellaria baicalensis, Polygonatum sibiricum, Drynaria fortunei, and Peucedanum praeruptorum assist the principal herbs, promoting blood circulation, dispelling wind and unblocking collaterals, relieving pain and strengthening the lower back; these are the assistant herbs. The adjuvant herbs, including North American ginseng, Polygonatum odoratum, and Ophiopogon japonicus, nourish yin and replenish qi; Saposhnikovia divaricata and Bupleurum chinense dispel wind and dampness; Boswellia carterii and Paeonia suffruticosa invigorate blood and remove blood stasis; Magnolia officinalis and Alisma plantago-aquatica regulate qi and resolve dampness; and stir-fried Ziziphus jujuba var. spinosa calms the mind and soothes the nerves. The entire formula harmonizes the qi and blood of the internal organs while also eliminating external pathogens, achieving the effect of supporting the body's resistance and eliminating pathogens, treating both the root cause and the symptoms.

[0027] The traditional Chinese medicine composition described in this invention is based on a formula developed through long-term clinical practice. It is highly targeted, possessing both the effects of strengthening the body's resistance and eliminating pathogenic factors. It can improve joint swelling, pain, and stiffness in rheumatoid arthritis, relieve various types of lower back pain, and regulate the body's constitution. The medicine is mild in nature, contains no toxic ingredients, and has high safety for long-term use, making it suitable for the treatment of chronic conditions. Clinical practice shows that it has a low recurrence rate in treating various types of rheumatoid arthritis and / or lower back pain, demonstrating high clinical application value.

[0028] The "parts by weight" of the active pharmaceutical ingredients described in this invention refers to the relative proportions of the active pharmaceutical ingredients, not their actual mass. Depending on the specific circumstances, one part by weight can be any mass, such as 1g, 10g, 50g, 500g, 1kg, etc. Detailed Implementation

[0029] The present invention will be described below with reference to specific embodiments. Those skilled in the art will understand that these embodiments are for illustrative purposes only and do not limit the scope of the invention in any way.

[0030] Unless otherwise specified, the experimental methods used in the following examples are conventional methods. Unless otherwise specified, the medicinal materials used in the following examples can be obtained commercially through public channels.

[0031] Example 1: A traditional Chinese medicine composition and its prepared decoction

[0032] The traditional Chinese medicine composition described in this embodiment is composed of the following raw materials (1g = 1 part by weight) based on a daily dose:

[0033] Angelica sinensis 12g, Ligusticum chuanxiong 9g, Rehmannia glutinosa 10g, Paeonia lactiflora 15g, Adenophora stricta 12g, Saposhnikovia divaricata 12g, Bupleurum chinense 10g, Scutellaria baicalensis 10g, Astragalus membranaceus 30g, Polygonatum sibiricum 15g, Paeonia suffruticosa 15g, Gentiana macrophylla 15g, Dipsacus asper 15g, Sargentodoxa cuneata 15g, Taxillus chinensis 12g, Polygonatum odoratum 15g, Ophiopogon japonicus 15g, Drynaria fortunei 12g, Achyranthes bidentata 15g, Alisma plantago-aquatica 20g, Ziziphus jujuba var. spinosa 30g, Magnolia officinalis 12g, Peucedanum praeruptorum 10g, Boswellia carterii 6g.

[0034] All the above ingredients are soaked in water and then decocted twice. The decoction is filtered while hot and the liquids are combined to obtain the decoction.

[0035] Dosage and administration: Take twice daily, morning and evening, warm. One dose per day, 30 days as one course of treatment.

[0036] Example 2: A traditional Chinese medicine composition and its prepared pills

[0037] The traditional Chinese medicine composition described in this embodiment is composed of the following raw materials (1g = 1 part by weight):

[0038] Angelica sinensis 15g, Ligusticum chuanxiong 10g, Rehmannia glutinosa 12g, Paeonia lactiflora 20g, Adenophora stricta 15g, Saposhnikovia divaricata 15g, Bupleurum chinense 15g, Scutellaria baicalensis 12g, Astragalus membranaceus 50g, Polygonatum sibiricum 20g, Paeonia suffruticosa 20g, Gentiana macrophylla 20g, Dipsacus asper 20g, Sargentodoxa cuneata 20g, Taxillus chinensis 16g, Polygonatum odoratum 20g, Ophiopogon japonicus 20g, Drynaria fortunei 15g, Achyranthes bidentata 20g, Alisma plantago-aquatica 30g, Ziziphus jujuba var. spinosa 50g, Magnolia officinalis 15g, Peucedanum praeruptorum 12g, Boswellia carterii 9g.

[0039] The above 24 ingredients are ground into fine powder, sieved, mixed evenly, and made into pills with water; or 100-120g of refined honey is added to every 100g of powder to make small honey pills or large honey pills (each large honey pill weighs 9g), thus obtaining pills.

[0040] Dosage and administration: Oral administration. Take 5g of water pills, 6g of water-honey pills, 9g of small honey pills, or 1 large honey pill twice a day. One course of treatment is 30 days.

[0041] Example 3: A traditional Chinese medicine composition and its prepared powder

[0042] The traditional Chinese medicine composition described in this embodiment is composed of the following raw materials (1g = 1 part by weight):

[0043] Angelica sinensis 12g, Ligusticum chuanxiong 10g, Rehmannia glutinosa 12g, Paeonia lactiflora 18g, Adenophora stricta 18g, Saposhnikovia divaricata 12g, Bupleurum chinense 12g, Scutellaria baicalensis 10g, Astragalus membranaceus 40g, Polygonatum sibiricum 18g, Paeonia suffruticosa 18g, Gentiana macrophylla 18g, Dipsacus asper 18g, Sargentodoxa cuneata 18g, Taxillus chinensis 15g, Polygonatum odoratum 18g, Ophiopogon japonicus 18g, Drynaria fortunei 14g, Achyranthes bidentata 18g, Alisma plantago-aquatica 25g, Ziziphus jujuba var. spinosa 40g, Magnolia officinalis 14g, Peucedanum praeruptorum 12g, Boswellia carterii 8g.

[0044] The above 24 ingredients are pulverized into a fine powder, sieved, and mixed evenly to obtain the powder.

[0045] Dosage and administration: Oral administration, 2-3g each time, twice a day.

[0046] Example 4: A traditional Chinese medicine composition and its prepared decoction

[0047] The traditional Chinese medicine composition described in this embodiment is composed of the following raw materials (1g = 1 part by weight) based on a daily dose:

[0048] Angelica sinensis 8g, Ligusticum chuanxiong 8g, Rehmannia glutinosa 6g, Paeonia lactiflora 10g, Adenophora stricta 10g, Saposhnikovia divaricata 8g, Bupleurum chinense 5g, Scutellaria baicalensis 8g, Astragalus membranaceus 15g, Polygonatum sibiricum 8g, Paeonia suffruticosa 10g, Gentiana macrophylla 10g, Dipsacus asper 10g, Sargentodoxa cuneata 10g, Taxillus chinensis 8g, Polygonatum odoratum 8g, Ophiopogon japonicus 8g, Drynaria fortunei 10g, Achyranthes bidentata 10g, Alisma plantago-aquatica 12g, Ziziphus jujuba var. spinosa 15g, Magnolia officinalis 8g, Peucedanum praeruptorum 6g, Boswellia carterii 4g.

[0049] The decoction was prepared according to the method in Example 1.

[0050] Dosage and administration: Take twice daily, morning and evening, warm. One dose per day, 30 days as one course of treatment.

[0051] Clinical medical records

[0052] Case 1: Rheumatoid Arthritis (Liver and Kidney Deficiency, Qi and Blood Insufficiency, and Rheumatism Stagnation)

[0053] Patient Information: Ms. Zhang, female, 52 years old. Initial visit date: March 10, 2024.

[0054] Initial consultation: The patient complained of recurrent swelling, pain, and stiffness in the metacarpophalangeal and proximal interphalangeal joints of both hands for over two years, which had worsened in the past month. The stiffness lasted for more than an hour every morning upon waking, and the swelling and pain significantly aggravated in cold weather or after exertion. The patient experienced limited range of motion in both hands, with difficulty in flexion and extension of the joints. Accompanying symptoms included general weakness, shortness of breath, reluctance to speak, lower back and knee pain, frequent awakenings at night, and general fatigue. Physical examination revealed mild swelling and significant tenderness in the interphalangeal joints of both hands, with limited range of motion, but no obvious joint deformities. The tongue was dark red with scattered petechiae, and the coating was thin, white, and slightly greasy. The pulse was deep, thready, and hesitant.

[0055] Western medicine diagnosis: Rheumatoid arthritis. Traditional Chinese medicine diagnosis: Bi syndrome, attributed to deficiency of liver and kidney, insufficiency of qi and blood, and obstruction of wind and dampness.

[0056] Treatment plan: The decoction of Example 1 of this invention is administered, one dose per day, taken warm in the morning and evening, for two consecutive courses of treatment (60 days). During this period, other anti-inflammatory, analgesic, and hormonal drugs should be discontinued. Avoid wind and cold, raw and cold foods, and engage in moderate joint activity.

[0057] Second consultation date: May 12, 2024.

[0058] Follow-up visit: After 60 days of medication, the swelling in the joints of both hands completely subsided, the morning stiffness was reduced to less than 5 minutes, joint pain on rainy days was almost gone, and the flexion and extension of the hands returned to normal. Symptoms of general weakness and shortness of breath significantly improved, lower back and knee pain were relieved, and sleep was sound at night. The tongue was pale red, the petechiae had faded, and the tongue coating was thin and white. The pulse was deep, slow, and gentle.

[0059] Follow-up diagnosis: The body's vital energy is gradually recovering, the wind-dampness and blood stasis have dissipated, and the arthralgia is basically cured.

[0060] The patient was instructed to take medication intermittently for maintenance, and there was no recurrence during a six-month follow-up.

[0061] Case 2: Degenerative lumbar pain (root cause: kidney deficiency; symptoms: rheumatism and blood stasis)

[0062] Patient Information: Mr. Li, male, 48 years old. Initial visit date: April 5, 2024.

[0063] Initial consultation: The patient complained of recurrent lower back pain, stiffness, and limited mobility for 3 years. In the past two months, the lower back pain worsened after prolonged sitting, exertion, bending over, or lifting heavy objects. Occasionally, the patient experienced a feeling of heaviness or numbness in the lower back. The pain and distension in the lower back were more pronounced in cold and damp environments. The patient also reported fatigue, weakness in the lower back and knees, restless sleep, and emotional distress. The tongue was dark in color with a white, greasy coating. The pulse was deep and thready.

[0064] Imaging examination revealed: degenerative changes in the lumbar spine and mild lumbar disc bulging.

[0065] Western medicine diagnosis: Degenerative changes in the lumbar spine, chronic lumbar muscle strain. Traditional Chinese medicine diagnosis: Lower back pain, syndrome differentiation: deficiency of liver and kidney, insufficiency of qi and blood, wind-dampness obstruction, and stagnation of meridians.

[0066] Treatment plan: Administer the decoction of Example 1 of this invention orally, one dose per day, divided into morning and evening warm doses, for one intensive treatment course (30 days). Avoid prolonged sitting or standing and heavy physical labor.

[0067] Second consultation date: May 6, 2024.

[0068] Follow-up visit: After 30 days of medication, the patient's lower back pain, heaviness, and stiffness completely disappeared. Prolonged sitting and bending over caused no discomfort, and the pain did not recur or worsen in cold, damp weather. General weakness and lower back and knee pain disappeared, and sleep quality significantly improved. The tongue was pale red with a thin white coating. The pulse was steady and strong.

[0069] Follow-up diagnosis: The liver and kidney qi and blood are abundant, the wind and dampness and blood stasis have been eliminated, the meridians in the waist are unblocked, and the disease has been cured.

[0070] No recurrence was observed during a 3-month follow-up period.

[0071] Case 3: Chronic lumbar muscle strain and lower back pain (liver and kidney deficiency, wind-dampness stagnation syndrome)

[0072] Patient information: Ms. Wang, 55 years old.

[0073] Initial consultation date: June 8, 2024

[0074] Initial consultation: The patient has experienced recurrent lower back pain and stiffness for 4 years, due to prolonged sitting and manual labor. The lower back pain worsens after exertion, with morning stiffness lasting for more than ten minutes. Discomfort and a feeling of heaviness occur in damp, cold, or rainy weather. Accompanying symptoms include fatigue, dizziness, tinnitus, and restless sleep. The patient is generally weak and intolerant to exertion. Physical examination: Stiffness and widespread tenderness in the lumbar muscles, without radiating pain in the lower extremities. The tongue is dark with a thin, slightly greasy white coating; the pulse is deep, thready, and hesitant.

[0075] Western medicine diagnosis: Chronic lumbar muscle strain. Traditional Chinese medicine diagnosis: Lower back pain, liver and kidney deficiency, and wind-dampness stagnation syndrome.

[0076] Treatment plan: Treat with the honey pills of Example 2 of this invention, one pill at a time, twice a day, taken with warm water, for two consecutive courses of treatment (60 days). Avoid wind and cold in daily life and do moderate back exercises.

[0077] Second consultation date: August 8, 2024.

[0078] Follow-up visit: The patient reported that after 30 days of medication, the stiffness and soreness in the lower back were significantly relieved, discomfort after exertion was greatly reduced, and sleep improved; after 60 days of medication, the lower back pain and stiffness completely disappeared, there was no discomfort on rainy days, physical strength returned to normal, and dizziness and fatigue disappeared. The tongue and pulse were normal, the meridians were unobstructed, and the qi and blood of the liver and kidneys were gradually replenished.

[0079] No recurrence was observed during the 4-month follow-up; the patient reported that the pills were convenient to take and that they were able to adhere to the prescribed dosage and timing.

[0080] Case 4: Mild Rheumatoid Arthritis (Qi and Blood Deficiency, Cold and Dampness Obstruction Syndrome)

[0081] Patient information: Zhao, male, 46 years old.

[0082] Initial consultation date: July 12, 2024.

[0083] Initial consultation: The patient presented with mild swelling, pain, and stiffness in the interphalangeal joints of both fingers for one year. The symptoms were recurrent and mild, with stiffness lasting about 10 minutes upon waking, which worsened after exposure to cold or exertion. Accompanied by general weakness, shortness of breath, and reluctance to speak, there was no obvious joint deformity. The tongue was pale and dark with a white, greasy coating, and the pulse was deep, thready, and slow.

[0084] Western medicine diagnosis: Rheumatoid arthritis (mild, stable phase). Traditional Chinese medicine diagnosis: Bi syndrome, Qi and blood deficiency, cold-dampness obstruction syndrome.

[0085] Treatment plan: Administer the powder of Example 3 of this invention, 2g each time, twice a day, dissolved in warm water, for one course of treatment (30 days).

[0086] Second consultation date: August 12, 2024.

[0087] Follow-up visit: The patient reported that after taking the medication for 15 days, the swelling, pain and stiffness of the joints were significantly reduced, and the symptoms of fatigue and shortness of breath were relieved; after taking the medication for 30 days, the symptoms of joint discomfort completely disappeared, there was no stiffness in the morning, and there was no recurrence after being exposed to cold. The patient's qi and blood were harmonized and the cold and dampness were eliminated.

[0088] The patient's condition remained stable for 3 months with no recurrence.

[0089] Case 5: Rheumatoid Arthritis with Rheumatic Obstruction Syndrome

[0090] Patient information: Ms. Sun, female, 38 years old.

[0091] Initial consultation date: February 15, 2024.

[0092] Initial consultation: Migratory soreness and swelling in the joints of the limbs, difficulty in flexion and extension, aversion to wind and cold, aggravated by wind, heaviness in the limbs, stiffness for about 20 minutes upon waking in the morning, no obvious chills or fever, accompanied by general fatigue. Pale red tongue with thin white coating, floating and slow pulse.

[0093] Diagnosis: Rheumatism obstruction, meridian blockage, and poor blood circulation.

[0094] Treatment plan: The decoction of Example 1 of this invention is taken once a day, warm in the morning and evening, for 30 days as one course of treatment.

[0095] Second consultation date: March 18, 2024.

[0096] Follow-up visit: The patient reported that after one course of treatment, the migratory joint pain and swelling completely subsided, the aversion to wind and heaviness in the limbs disappeared, joint movement was free, morning stiffness was eliminated, and the tongue and pulse were normal.

[0097] No recurrence was observed during the 2-month follow-up period.

[0098] Case 6: Rheumatoid Arthritis with Cold-Dampness Obstruction Syndrome

[0099] Patient information: Zhou, male, 42 years old.

[0100] Initial consultation date: January 20, 2024.

[0101] Initial consultation: The patient reported cold, painful, and swollen joints in both hands and wrists. The pain was fixed and did not move, and it worsened in cold and damp weather, while it was slightly relieved by warmth. Examination revealed significant joint stiffness, cold limbs, cold hands and feet, and fatigue. The tongue was pale with a thick, greasy white coating, and the pulse was deep and slow.

[0102] Diagnosis: Cold-dampness stagnation, obstruction of meridians, and malnourishment of muscles and bones.

[0103] Treatment plan: Administer the decoction of Example 1 of this invention, one dose per day, taken warm in the morning and evening, for 60 consecutive days.

[0104] Second consultation date: March 22, 2024.

[0105] Follow-up visit: The patient reported that after taking the medication for 30 days, the joint pain and stiffness were significantly relieved, and the symptoms of aversion to cold improved; after 60 days, all symptoms disappeared, and there was no recurrence when exposed to cold weather, and the limbs were warm and the movement was normal.

[0106] Analysis: The formula contains ginger, magnolia bark, and alisma to dispel dampness and cold, and mulberry mistletoe and drynaria to warm and nourish tendons and bones. The combination of the principal and assistant herbs warms and unblocks the meridians, dispels cold and dampness, and addresses both the root cause and the symptoms.

[0107] Case 7: Rheumatoid Arthritis with Damp-Heat Obstruction Syndrome

[0108] Patient information: Ms. Wu, 45 years old.

[0109] Initial consultation date: August 10, 2024.

[0110] Initial consultation: Redness, swelling, heat, and pain in both wrists and knees, with burning sensation upon touch, aggravated by pressure, and limited range of motion. Accompanied by dry mouth with slight thirst, irritability, and dark yellow urine, with significant stiffness upon waking. The tongue is red with a yellow, greasy coating, and the pulse is slippery and rapid.

[0111] Diagnosis: Damp-heat accumulation, joint obstruction, and stagnation of qi and blood.

[0112] Treatment plan: Administer the decoction of Example 1, one dose per day, taken warm in the morning and evening, for 45 consecutive days.

[0113] Second consultation date: October 28, 2024.

[0114] Follow-up visit: The patient reported that after taking the medication for 15 days, the redness, swelling and burning sensation in the joints subsided and the pain was relieved; after 45 days, the joint swelling, pain and stiffness completely disappeared, the symptoms of irritability and dry mouth were eliminated, and bowel movements and urination became regular.

[0115] Analysis: Scutellaria baicalensis and Paeonia suffruticosa in the formula clear heat, cool blood, remove dampness and detoxify, while Rehmannia glutinosa and Ophiopogon japonicus nourish yin and clear heat. This formula is suitable for the pathogenesis of damp-heat obstruction syndrome with heat symptoms.

[0116] Case 8: Rheumatoid Arthritis with Phlegm-Blood Stasis and Arthralgia

[0117] Patient information: Zheng, female, 56 years old.

[0118] Initial consultation date: September 5, 2024.

[0119] Initial consultation: Multiple joints throughout the body are swollen, stiff, and have fixed stabbing pain. The swollen joints are hard to the touch. There is numbness in the limbs, accompanied by chest tightness, excessive phlegm, and heaviness in the limbs. The disease has been prolonged for 3 years with recurrent attacks. The tongue is dark purple with a white, greasy coating, and the pulse is wiry and hesitant.

[0120] Diagnosis: Phlegm and blood stasis obstruction, meridian blockage, and malnourishment of muscles and bones.

[0121] Treatment plan: Administer 6g of the water-honey pills from Example 2 twice a day for 60 days (2 courses of treatment).

[0122] Second consultation date: November 8, 2024.

[0123] Follow-up visit: The patient reported that after taking the medication for 2 months, the joint stiffness and swelling subsided, the tingling and numbness disappeared, the chest tightness and excessive phlegm were relieved, and the joints became more flexible.

[0124] Analysis: The formula contains frankincense, chuanxiong, and daxueteng to invigorate blood circulation, remove blood stasis, unblock the meridians, and relieve pain; ginger, magnolia bark, and alisma to regulate qi, resolve phlegm, eliminate dampness, and dissipate nodules. It treats both phlegm and blood stasis, unblocks the meridians, and relieves numbness, which is consistent with the core pathogenesis of this syndrome.

[0125] Case 9: Rheumatoid Arthritis with Blood Stasis and Obstruction of Collaterals

[0126] Patient Information: Mr. Chen, male, 53 years old. Initial visit date: October 12, 2024.

[0127] Initial consultation: Fixed stabbing pain in the fingers and elbows, worse at night; dull complexion and dry skin around the joints; stiffness and limited range of motion in the joints; long-term illness with recurrent flare-ups. The tongue is purplish-dark with prominent ecchymosis, and the coating is thin and white; the pulse is deep, thready, and hesitant.

[0128] Diagnosis: Blood stasis, obstruction of meridians, and pain due to obstruction.

[0129] Treatment plan: Administer the decoction of Example 1, one dose per day, taken warm in the morning and evening, for 60 consecutive days.

[0130] Second consultation date: December 16, 2024.

[0131] Follow-up visit: The patient reported that after taking the medication for one month, the night pain had basically disappeared and the skin color of the joints had gradually become more radiant; after two months, the blood stasis had completely dissipated, the joint pain and stiffness had completely subsided, and the patient's mobility had returned to normal.

[0132] Analysis: The formula contains frankincense, peony bark, and large-stem vine to invigorate blood circulation, remove blood stasis, and relieve pain; chuanxiong promotes qi circulation and invigorates blood circulation, specifically targeting chronic arthralgia and blood stasis obstructing the meridians.

[0133] Case 10: Rheumatoid Arthritis with Deficiency of Both Qi and Blood

[0134] Patient information: Ms. He, female, 49 years old.

[0135] Initial consultation date: November 8, 2024.

[0136] Initial consultation: Multiple joint pain and soreness, aggravated by exertion, with mild stiffness upon waking, accompanied by sallow complexion, fatigue, palpitations, shortness of breath, poor appetite, and general weakness. The patient is usually weak and easily fatigued. The tongue is pale with a thin white coating, and the pulse is thready and weak.

[0137] Diagnosis: Deficiency of Qi and Blood, lack of nourishment to tendons and bones, and lingering pathogenic factors.

[0138] Treatment plan: Administer the powder of Example 3, 2g each time, twice a day, dissolved in warm water, for 45 consecutive days.

[0139] Second consultation date: December 25, 2024.

[0140] Follow-up visit: The patient reported that after taking the medication for half a month, the symptoms of fatigue and palpitations had significantly improved, and the joint pain had been reduced; after taking the medication for 45 days, the joint discomfort had completely disappeared, and the patient's complexion had become rosy and physical strength had been restored.

[0141] Analysis: The formula contains Astragalus membranaceus, Angelica sinensis, Polygonatum sibiricum, and Paeonia lactiflora, which invigorate qi and nourish blood, replenish the body's foundation, fundamentally improve qi and blood deficiency, strengthen the body's resistance, eliminate pathogens, and prevent recurrence.

[0142] Medical Case 11: Rheumatoid Arthritis with Liver and Kidney Deficiency Syndrome

[0143] Patient information: Gao, male, 60 years old.

[0144] Initial consultation date: December 3, 2024.

[0145] Initial consultation: The patient presents with recurring dull pain and stiffness in all joints, sometimes mild and sometimes severe, accompanied by soreness and weakness in the lower back and knees, dizziness, tinnitus, fatigue, and cold limbs. The condition has persisted for 5 years and worsens after exertion or exposure to cold. The tongue is pale with a thin white coating, and the pulse is deep, thready, and weak.

[0146] Diagnosis: Deficiency of liver and kidney, malnourishment of tendons and bones, and retention of pathogenic factors in the meridians.

[0147] Treatment plan: Administer the small honey pills from Example 2, 9g each time, twice a day, for 90 consecutive days.

[0148] Second consultation date: March 5, 2025.

[0149] Follow-up visit: The patient reported that after taking the medication for 3 months, the stiffness and dull pain in the joints completely subsided, the symptoms of soreness in the lower back and knees, dizziness and tinnitus disappeared, the physical condition significantly improved, and the ability to withstand cold and fatigue increased.

[0150] There was no recurrence during the subsequent six-month follow-up.

[0151] Analysis: The formula contains Loranthus parasiticus, Dipsacus asper, Drynaria fortunei, and Achyranthes bidentata to nourish the liver and kidneys, strengthen tendons and bones, and is combined with qi-tonifying and blood-nourishing ingredients to consolidate the foundation and provide long-term conditioning.

[0152] Medical Case Twelve: Rheumatoid Arthritis with Qi and Yin Deficiency Syndrome

[0153] Patient information: Ms. Lin, 54 years old.

[0154] Initial consultation date: January 10, 2025.

[0155] Initial consultation: Joint soreness and dull pain, stiffness worsening in the afternoon, accompanied by fatigue, shortness of breath, reluctance to speak, dry mouth and throat, night sweats, poor sleep with vivid dreams, chronic illness and weakness, prolonged illness. Tongue is reddish with little moisture, thin coating, and pulse is thready and slow.

[0156] Diagnosis: Deficiency of both Qi and Yin, lack of lubrication in the meridians, and stagnation of residual pathogens.

[0157] Treatment plan: Administer the decoction of Example 1, one dose per day, taken warm in the morning and evening, for 60 consecutive days.

[0158] Second consultation date: May 13, 2025.

[0159] Follow-up visit: The patient reported that after taking the medication for 20 days, symptoms such as dry mouth, hot flashes, and insomnia were relieved, and joint soreness and swelling were reduced; after 60 days, Qi and Yin were restored, all symptoms disappeared, and joint movement returned to normal.

[0160] Analysis: Astragalus and Polygonatum in the formula invigorate Qi and strengthen the spleen, while Adenophora stricta, Ophiopogon japonicus, and Polygonatum odoratum nourish Yin and generate fluids. It replenishes Qi, blood, and Yin fluids simultaneously, making it suitable for chronic illness with Qi and Yin deficiency and arthralgia.

[0161] Case 13: Rheumatoid arthritis complicated with degenerative lumbar pain (liver and kidney deficiency, qi and blood stagnation, and rheumatism syndrome)

[0162] Patient information: Zhang, male, 51 years old.

[0163] Initial consultation date: February 18, 2025

[0164] Initial consultation: The patient presented with swelling and pain in the interphalangeal joints of both fingers, and morning stiffness for 1.5 years, diagnosed with rheumatoid arthritis. Simultaneously, the patient experienced recurrent lower back pain and stiffness for 3 years, which worsened after prolonged sitting or bending over. Both symptoms were exacerbated on rainy days, accompanied by weakness in the lower back and knees, fatigue, and poor sleep. Imaging findings revealed inflammatory changes in rheumatoid arthritis, degenerative changes in the lumbar spine, and mild disc herniation. The tongue was dark red with scattered petechiae, and the coating was thin, white, and slightly greasy; the pulse was deep, thready, and hesitant.

[0165] Western medicine diagnosis: Rheumatoid arthritis, degenerative changes in the lumbar spine combined with lumbar muscle strain. Traditional Chinese medicine diagnosis: Deficiency of liver and kidney is the root cause, while stagnation of qi and blood and obstruction by wind and dampness are the symptoms, resulting in blocked meridians and malnourishment of muscles and bones.

[0166] Treatment plan: Administer the decoction of Example 1, one dose per day, taken warm in the morning and evening, for two consecutive courses of treatment (60 days). Discontinue other anti-inflammatory and analgesic drugs, avoid wind and cold, and avoid overexertion.

[0167] Second consultation date: April 21, 2025

[0168] Follow-up visit: The patient reported that after 30 days of medication, the swelling and pain in the joints of both hands and morning stiffness were significantly relieved, the stiffness and soreness in the lower back were reduced, and fatigue and insomnia improved; after 60 days of medication, the morning stiffness in the joints disappeared, the swelling and pain completely subsided, the lower back could move freely, and there were no discomfort symptoms after prolonged sitting, labor, or rainy days; the symptoms of lower back and knee weakness and mental fatigue were completely relieved. The tongue was pale red without petechiae, and the pulse was steady and strong. The liver and kidney qi and blood were abundant, the wind and dampness and blood stasis were completely eliminated, and the meridians throughout the body were unobstructed.

[0169] During the 5-month follow-up, there was no recurrence of rheumatoid arthritis and lower back pain symptoms.

[0170] Analysis: This case fully demonstrates the core advantage of the traditional Chinese medicine composition of this invention, which is "treating different diseases with the same method". It targets the common pathogenesis of rheumatoid arthritis and low back pain, which is both deficiency and excess. It nourishes the liver and kidneys and replenishes qi and blood to strengthen the root, while dispelling wind and dampness, clearing the meridians and dispersing blood stasis to treat the symptoms. It can effectively improve joint and lumbar lesions at the same time, and takes into account both eliminating pathogens in acute cases and strengthening the root in chronic diseases. It is suitable for long-term treatment and conditioning of complex rheumatic and bone diseases.

[0171] Summary of treatment efficacy in medical cases:

[0172] Clinically proven, the herbal composition of this invention targets rheumatoid arthritis, acute and chronic low back pain caused by liver and kidney deficiency, qi and blood deficiency, and wind-dampness stagnation. It addresses both the symptoms and the root cause, quickly eliminating core symptoms such as joint swelling, stiffness, and lower back and knee pain, repairing the body's inherent weakness, and improving accompanying systemic symptoms such as sleep and fatigue. It has a definite curative effect, stable efficacy, low long-term recurrence rate, and no adverse reactions throughout the course of treatment. It is safe to use and suitable for long-term standardized treatment of various types of rheumatoid arthritis and acute and chronic low back pain.

Claims

1. A traditional Chinese medicine composition for rheumatoid arthritis and / or low back pain, comprising the following raw materials in parts by weight: Angelica sinensis 6-15 parts, Ligusticum chuanxiong 6-10 parts, Rehmannia glutinosa 3-12 parts, Paeonia lactiflora 6-20 parts, Adenophora stricta 6-15 parts, Saposhnikovia divaricata 6-15 parts, Bupleurum chinense 3-15 parts, Scutellaria baicalensis 6-12 parts, Astragalus membranaceus 10-50 parts, Polygonatum sibiricum 6-20 parts, Paeonia suffruticosa 6-20 parts, Gentiana macrophylla 6-20 parts, Dipsacus asper 6-20 parts, Sargentodoxa cuneata 6-20 parts, Taxillus chinensis 6-16 parts, Polygonatum odoratum 6-20 parts, Ophiopogon japonicus 6-20 parts, Drynaria fortunei 10-15 parts, Achyranthes bidentata 6-20 parts, Alisma plantago-aquatica 10-30 parts, Ziziphus jujuba var. spinosa 10-50 parts, Magnolia officinalis 6-15 parts, Peucedanum praeruptorum 3-12 parts, Boswellia carterii 3-9 parts.

2. The traditional Chinese medicine composition according to claim 1, characterized in that, The traditional Chinese medicine composition consists of the following raw materials in parts by weight: Angelica sinensis 8-12 parts, Ligusticum chuanxiong 8-10 parts, Rehmannia glutinosa 6-12 parts, Paeonia lactiflora 10-18 parts, Adenophora stricta 10-18 parts, Saposhnikovia divaricata 8-12 parts, Bupleurum chinense 5-12 parts, Scutellaria baicalensis 8-10 parts, Astragalus membranaceus 15-40 parts, Polygonatum sibiricum 8-18 parts, Paeonia suffruticosa 10-18 parts, Gentiana macrophylla 10-18 parts, Dipsacus asper 10-18 parts, Sargentodoxa cuneata 10-18 parts, Taxillus chinensis 8-15 parts, Polygonatum odoratum 8-18 parts, Ophiopogon japonicus 8-18 parts, Drynaria fortunei 10-14 parts, Achyranthes bidentata 10-18 parts, Alisma plantago-aquatica 12-25 parts, Ziziphus jujuba var. spinosa 15-40 parts, Magnolia officinalis 8-14 parts, Peucedanum praeruptorum 6-12 parts, Boswellia carterii 4-8 parts.

3. The traditional Chinese medicine composition according to claim 2, characterized in that, The traditional Chinese medicine composition consists of the following raw materials in parts by weight: Angelica sinensis 10-12 parts, Ligusticum chuanxiong 8-9 parts, Rehmannia glutinosa 8-10 parts, Paeonia lactiflora 12-15 parts, Adenophora stricta 10-12 parts, Saposhnikovia divaricata 10-12 parts, Bupleurum chinense 8-10 parts, Scutellaria baicalensis 9-10 parts, Astragalus membranaceus 20-30 parts, Polygonatum sibiricum 12-15 parts, Paeonia suffruticosa 12-15 parts, Gentiana macrophylla 12-15 parts, Dipsacus asper 12-15 parts, Sargentodoxa cuneata 12-15 parts, Taxillus chinensis 10-12 parts, Polygonatum odoratum 12-15 parts, Ophiopogon japonicus 12-15 parts, Drynaria fortunei 12-13 parts, Achyranthes bidentata 12-15 parts, Alisma plantago-aquatica 15-20 parts, Ziziphus jujuba var. spinosa 20-30 parts, Magnolia officinalis 10-12 parts, Peucedanum praeruptorum 8-10 parts, Boswellia carterii 5-7 parts.

4. The traditional Chinese medicine composition according to claim 3, characterized in that, Composed of the following parts by weight of active pharmaceutical ingredient: Take 12 parts Angelica sinensis, 9 parts Ligusticum chuanxiong, 10 parts Rehmannia glutinosa, 15 parts Paeonia lactiflora, 12 parts Adenophora stricta, 12 parts Saposhnikovia divaricata, 10 parts Bupleurum chinense, 10 parts Scutellaria baicalensis, 30 parts Astragalus membranaceus, 15 parts Polygonatum sibiricum, 15 parts Paeonia suffruticosa, 15 parts Gentiana macrophylla, 15 parts Dipsacus asper, 15 parts Sargentodoxa cuneata, 12 parts Taxillus chinensis, 15 parts Polygonatum odoratum, 15 parts Ophiopogon japonicus, 12 parts Drynaria fortunei, 15 parts Achyranthes bidentata, 20 parts Alisma plantago-aquatica, 30 parts stir-fried Ziziphus jujuba var. spinosa, 12 parts Magnolia officinalis, 10 parts Peucedanum praeruptorum, and 6 parts Boswellia carterii.

5. The use of the traditional Chinese medicine composition according to any one of claims 1 to 4 in the preparation of a medicament for rheumatoid arthritis and / or low back pain.

6. The application according to claim 5, characterized in that, The rheumatoid arthritis mentioned includes various types of rheumatoid arthritis, including rheumatic obstruction syndrome, cold-damp obstruction syndrome, damp-heat obstruction syndrome, phlegm-blood stasis obstruction syndrome, blood stasis obstruction syndrome, qi and blood deficiency syndrome, liver and kidney deficiency syndrome, and qi and yin deficiency syndrome. Preferably, the lower back pain is musculoskeletal related lower back pain, selected from one or more of the following: kidney deficiency lower back pain, rheumatic obstruction lower back pain, lumbar muscle strain, and lumbar degenerative disease; Preferably, the rheumatoid arthritis and / or low back pain are characterized by aching and pain in the limbs and joints or lower back, heaviness and stiffness, limited mobility, aggravation by exposure to wind, cold and dampness, significant exacerbation of symptoms after exertion, limited limb flexion and extension, accompanied by fatigue, shortness of breath, reluctance to speak, soreness and weakness in the lower back and knees, emotional distress, and poor sleep; the tongue is dark or has petechiae, and the tongue coating is thin white or slightly greasy; the pulse is deep and thready, deep and hesitant, or thready and slow.

7. A medicament for rheumatoid arthritis and / or low back pain, prepared using the traditional Chinese medicine composition of any one of claims 1 to 4 as the active ingredient; Preferably, the traditional Chinese medicine composition is the only active ingredient of the drug.

8. The medicament according to claim 7, characterized in that, The rheumatoid arthritis mentioned includes various types of rheumatoid arthritis, including rheumatic obstruction syndrome, cold-damp obstruction syndrome, damp-heat obstruction syndrome, phlegm-blood stasis obstruction syndrome, blood stasis obstruction syndrome, qi and blood deficiency syndrome, liver and kidney deficiency syndrome, and qi and yin deficiency syndrome. Preferably, the lower back pain is musculoskeletal related lower back pain, selected from one or more of the following: kidney deficiency lower back pain, rheumatic obstruction lower back pain, lumbar muscle strain, and lumbar degenerative disease; Preferably, the rheumatoid arthritis and / or low back pain are characterized by aching and pain in the limbs and joints or lower back, heaviness and stiffness, limited mobility, aggravation by exposure to wind, cold and dampness, significant exacerbation of symptoms after exertion, limited limb flexion and extension, accompanied by fatigue, shortness of breath, reluctance to speak, soreness and weakness in the lower back and knees, emotional distress, and poor sleep; the tongue is dark or has petechiae, and the tongue coating is thin white or slightly greasy; the pulse is deep and thready, deep and hesitant, or thready and slow.

9. The drug according to claim 7 or 8, characterized in that, The drug is a clinically acceptable formulation that includes pharmaceutically acceptable excipients.

10. The medicament according to claim 9, characterized in that, The preparation is an oral preparation; Preferably, the oral preparation is selected from decoctions, tablets, capsules, powders, pills, or granules.