A kind of severe continuous plasma replacement pipeline anti-coagulation sterile flushing control device

Abstract

The application relates to the field of medical blood purification devices, and discloses a severe continuous plasma replacement pipeline anti-coagulation sterile flushing regulation device, which comprises a transparent tube, the front end of the transparent tube is fixedly connected with a connecting tube, the rear end of the transparent tube is provided with a Venturi self-suction structure, the surface of the Venturi self-suction structure is detachably installed with an automatic liquid changing mechanism through a quick release assembly, the Venturi self-suction structure is used for realizing the flow matching of flushing liquid and the main plasma pipeline, the quick release assembly is used for realizing the integral modularization of the automatic liquid changing mechanism, the negative pressure generated by the flow of the main pipeline plasma is used for automatically sucking the flushing liquid, the suction amount of the flushing liquid is dynamically and adaptively matched with the flow of the main plasma, no additional power is needed for driving, the pipeline coagulation caused by insufficient flow can be avoided, the flushing liquid can prevent the excessive dilution of blood, the flow matching is accurate in the whole process, the anti-coagulation effect is stable and reliable, and the smooth operation of the continuous plasma replacement treatment is effectively ensured.

Description

Technical Field

[0001] This invention relates to the field of blood purification technology for medical devices, specifically a sterile flushing and control device for anticoagulation in continuous plasma exchange tubing for critical care. Background Technology

[0002] Continuous plasma exchange (CPPE) is a crucial blood purification technique for treating critically ill patients with severe liver and kidney failure, autoimmune diseases, and acute poisoning. During treatment, anticoagulant flushing fluid must be continuously injected into the tubing to prevent clogging of the tubing and filters. Strict aseptic technique must be followed throughout the procedure to prevent air ingress and external contamination. The accuracy of the flushing fluid infusion rate, the safety of the fluid exchange procedure, and the aseptic technique directly affect the continuity of treatment, patient safety, and treatment outcome, representing the core challenges in the nursing care of critical care blood purification tubing.

[0003] Traditional plasma exchange flushing often involves manually suspending the infusion bag and manually adjusting the drip rate. This not only requires frequent rounds and manual fluid changes by medical staff, significantly increasing the workload, but also makes it easy to introduce air during the fluid change process, leading to serious medical risks such as air embolism. At the same time, it is difficult to accurately match the plasma flow rate with manual dripping. Insufficient flow can easily induce blood clotting and blockage in the tubing, while excessive flow can dilute the blood and affect the treatment effect. Furthermore, the open operation also increases the risk of tubing contamination and nosocomial infection, making it difficult to meet the safety needs of critically ill patients for long-term continuous treatment. Summary of the Invention

[0004] To address the shortcomings of existing technologies, this invention provides a sterile flushing and control device for anticoagulation in continuous plasma exchange tubing for critically ill patients, which solves the problem of high risk of air ingress and coagulation during fluid exchange.

[0005] To achieve the above objectives, the present invention is implemented through the following technical solution: a sterile flushing and control device for anticoagulation of continuous plasma exchange tubing in critical care, comprising a transparent tube, wherein a connecting tube is fixedly connected to the front end of the transparent tube, and a Venturi self-priming structure is provided at the rear end of the transparent tube, wherein an automatic fluid replacement mechanism is detachably installed on the surface of the Venturi self-priming structure through a quick-release component.

[0006] The Venturi self-priming structure is used to match the flow rate of the flushing fluid with that of the main slurry line;

[0007] Quick-release components are used to enable the modular installation and disassembly of the automatic fluid changing mechanism.

[0008] The automatic fluid replacement mechanism allows for the simultaneous placement of two sets of flushing fluids, and automatically switches to another set once one set is used up.

[0009] Preferably, the Venturi self-priming structure includes a connecting sleeve fixedly connected to the rear end of the connecting tube, and the connecting sleeve is provided in two sets, with a thin tube fixedly connected between the two sets of connecting sleeves.

[0010] Preferably, the opposite surfaces of the two sets of connecting sleeves are tapered, and the diameter of the thin tube is the same as the diameter of the tapered part of the connecting sleeve.

[0011] Preferably, the automatic fluid changing mechanism includes a three-way turntable, a connector plug is fixedly connected to the front end of the three-way turntable, a one-way valve is provided on the outer arc surface of the connector plug, a rotating disk is elastically connected to the top end of the three-way turntable by a spiral spring, and two sets of external connectors are fixedly connected to the outer sidewall of the rotating disk.

[0012] Preferably, the three-way turntable is rotatably connected to the inner sidewall of the turntable.

[0013] Preferably, the outer arc surface of the three-way turntable has two sets of holes and slots that match the diameter of the external connector.

[0014] Preferably, one end of the spiral spring is fixedly connected to the top of the inner wall of the rotating disk, and the other end of the spiral spring is fixedly connected to the upper surface of the external connector.

[0015] Preferably, the quick-release assembly includes a push rod, which is elastically connected to the inner wall of the top end of the thin tube by a return spring, and the inner side wall of the thin tube is provided with a valve.

[0016] Preferably, the outer arc surface of the connector has a slot, the connector is inserted into the slot on the outer wall of the thin tube, and the connector is inserted into the valve.

[0017] Preferably, the insertion rod passes through and is slidably connected to the inner wall of the outer top end of the thin tube, one end of the return spring is fixedly connected to the surface of the insertion rod, the other end of the return spring is fixedly connected to the inner wall of the top end of the thin tube, and the bottom end of the outer wall of the insertion rod is inserted into the inner wall of the slot.

[0018] This invention provides a sterile flushing and control device for anticoagulation in continuous plasma exchange tubing for critical care. It offers the following advantages:

[0019] 1. This invention adopts a Venturi self-priming flushing structure, which automatically draws in flushing fluid by utilizing the negative pressure generated by the main plasma flow. The amount of flushing fluid drawn in is dynamically matched adaptively with the main plasma flow rate, without the need for additional power drive. This can avoid insufficient flow causing tubing coagulation and prevent excessive dilution of blood by the flushing fluid. The flow rate matching is precise throughout the process, and the anticoagulation effect is stable and reliable, effectively ensuring the smooth operation of continuous plasma exchange therapy.

[0020] 2. This invention is equipped with a gravity-driven double-bag automatic fluid exchange mechanism, which automatically switches the fluid path by relying on the weight difference between the two bags of flushing fluid. The switching process is completely sealed and there is no air intrusion, which completely eliminates the risk of air embolism caused by manual fluid exchange. At the same time, it does not require electric drive or manual supervision, which greatly reduces the workload of medical staff. The one-way valve design can effectively prevent backflow of fluid and contamination of flushing fluid, ensuring the sterility and safety of the entire treatment process.

[0021] 3. This invention adopts a quick-release modular design. The automatic fluid replacement mechanism can be quickly disassembled and replaced through the insertion rod structure. The interface has a built-in valve for automatic sealing. During the disassembly and assembly process, the inside of the tubing remains in a sealed and sterile state, which not only facilitates the replacement of consumables in clinical practice, but also avoids tubing contamination. The modular structure allows for the replacement of the fluid replacement component separately, without the need to scrap the entire tubing, effectively reducing the cost of treatment consumables and adapting to the needs of large-scale clinical use. Attached Figure Description

[0022] Figure 1 This is an overall perspective view of the present invention;

[0023] Figure 2 This is a partial cross-sectional view of the thin tube structure of the present invention;

[0024] Figure 3 For the present invention Figure 2 Enlarged structural diagram of section A;

[0025] Figure 4 This is a three-dimensional structural diagram of the automatic fluid changing mechanism of the present invention;

[0026] Figure 5 This is a partial cross-sectional view of the three-way turntable of the present invention;

[0027] Figure 6 This is a three-dimensional structural diagram of the spiral spring of the present invention.

[0028] Among them, 1. Transparent tube; 2. Connecting tube; 3. Venturi self-priming structure; 31. Connecting sleeve; 32. Thin tube; 4. Quick release assembly; 41. Insert rod; 42. Return spring; 43. Valve; 5. Automatic fluid changing mechanism; 51. Rotary disc; 52. Connecting plug; 53. One-way valve; 54. External connector; 55. Three-way rotary disc; 56. Spiral spring. Detailed Implementation

[0029] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0030] Example:

[0031] Please see the appendix Figure 1 -Appendix Figure 6 This invention provides a sterile flushing and control device for anticoagulation of continuous plasma exchange tubing in critical care, including a transparent tube 1, a connecting tube 2 fixedly connected to the front end of the transparent tube 1, a Venturi self-priming structure 3 provided at the rear end of the transparent tube 1, and an automatic fluid exchange mechanism 5 detachably installed on the surface of the Venturi self-priming structure 3 through a quick-release component 4.

[0032] The Venturi self-priming structure 3 is used to match the flow rate of the flushing fluid with that of the main slurry pipeline;

[0033] Quick-release component 4 is used to enable the modular installation and disassembly of the automatic fluid changing mechanism 5.

[0034] The automatic fluid changing mechanism 5 is used to simultaneously hang two sets of flushing fluid, and can automatically switch after one set of flushing fluid is used up.

[0035] Reference Figures 2-3 The Venturi self-priming structure 3 includes a connecting sleeve 31 fixedly connected to the rear end of the connecting tube 2. The opposite surfaces of the two sets of connecting sleeves 31 are tapered. The diameter of the thin tube 32 is the same as the diameter of the tapered part of the connecting sleeve 31. There are two sets of connecting sleeves 31, and a thin tube 32 is fixedly connected between the two sets of connecting sleeves 31. A connector is opened on the outside of the thin tube 32. By making the two sets of connecting sleeves 31 thinner from thicker and connecting them with the thin tube 32 in the middle, the flow rate increases sharply and the pressure drops sharply when the main liquid flows through the thin tube 32, thus naturally forming a local negative pressure vacuum. This negative pressure directly draws the flushing liquid at the connector into the thin tube 32. The faster the flow rate in the thin tube 32, the greater the negative pressure and the more flushing liquid is drawn in.

[0036] Reference Figures 4-6 The automatic fluid changing mechanism 5 includes a three-way turntable 55, which is rotatably connected to the inner side wall of the turntable 51. A connector 52 is fixedly connected to the front end of the three-way turntable 55. A one-way valve 53 is provided on the outer arc surface of the connector 52, so that the internal flushing fluid can only enter the interior of the thin tube 32 through the one-way valve 53. The flushing fluid inside the thin tube 32 will not flow backward. The top of the three-way turntable 55 is elastically connected to the turntable 51 through a spiral spring 56. One end of the spiral spring 56 is fixedly connected to the top of the inner wall of the turntable 51, and the other end of the spiral spring 56 is fixedly connected to the upper surface of the external connector 54. The function of the spiral spring 56 is to keep the position of the turntable 51 on the surface of the three-way turntable 55 in a centered state, so that the inner side of the turntable 51 and the liquid inlet of the three-way turntable 55 can be blocked and misaligned, thereby preventing air from entering the interior through the external connector 54 and the two sets of liquid inlets of the three-way turntable 55.

[0037] Furthermore, two sets of external connectors 54 are fixedly connected to the outer sidewall of the rotating disk 51. The function of the external connectors 54 is to connect with the rinsing fluid of the two sets of external bags. Initially, the two sets of rinsing fluid bags are designated as A and B, and the initial weight of bag A is greater than that of bag B. When connecting with the external connectors 54, the weight of bag A will pull the rotating disk 51, causing the external connectors 54 to align with one side inlet of the three-way rotating disk 55. At this time, the external connectors 54 at the connection point of bag B will be lifted upwards due to their weight, thus allowing the connection to be aligned. The external connector 54 is misaligned with the inlet of the three-way turntable 55. After bag A is fully aspirated, the weight of bag B will cause the turntable 51 to rotate, thereby aligning the external connector 54 with the inlet of the three-way turntable 55. At this time, the external connector 54 of bag A will be unblocked from the current inlet of the three-way turntable 55, thus realizing the switching between bags A and B. This prevents air from entering when medical staff switch the irrigation fluid. The three-way turntable 55 is rotatably connected to the inner side wall of the turntable 51.

[0038] Reference Figures 2-3 The quick-release assembly 4 includes a rod 41, which is elastically connected to the inner wall of the top end of the thin tube 32 via a return spring 42. A valve 43 is provided on the inner side wall of the thin tube 32. A slot is provided on the outer arc surface of the connector 52. The bottom end of the outer wall of the rod 41 is inserted into the inner wall of the slot. The insertion between the two allows the connector 52 to drive the rotating disk 51 and the three-way rotating disk 55 to be installed and fixed on the outer wall of the thin tube 32. One end of the return spring 42 is fixedly connected to the surface of the rod 41, and the other end of the return spring 42 is fixedly connected to the inner wall of the top end of the thin tube 32. The function of the return spring 42 is to automatically reset the position of the rod 41 after it is pulled outward. The rod 41 passes through and slides on the inner wall of the outer top end of the thin tube 32. The connector 52 is inserted into the slot on the outer wall of the thin tube 32 and is inserted into the valve 43. A sealing ring is provided on the outer arc surface of the connector 52 to increase the sealing effect during insertion.

[0039] Working principle: Transparent tube 1 and connecting tube 2 are connected in series to the main plasma exchange circuit. Transparent tube 1 allows medical staff to directly observe the flow of liquid in the tubing. Venturi self-priming structure 3 uses the negative pressure generated by the flow of the main plasma to automatically draw in the flushing fluid. Automatic fluid exchange mechanism 5 realizes the airless automatic switching of the two bags of flushing fluid. Quick-release component 4 realizes the modular aseptic disassembly and assembly of the fluid exchange mechanism. The whole process is closed-loop operation, ensuring the asepticity and flow self-matching of anticoagulant flushing during continuous plasma exchange.

[0040] The main plasma enters the Venturi self-priming structure 3 through the connecting tube 2. When it flows through the capillary tube 32 between the two sets of connecting sleeves 31 with tapered transitions, the tube diameter suddenly narrows, causing the flow velocity to increase sharply and the pressure to drop significantly. According to Bernoulli's principle, a stable local negative pressure is formed at the connector on the side wall of the capillary tube 32, which automatically draws the flushing fluid into the main path and mixes it evenly with the plasma. The negative pressure intensity at the capillary tube 32 adapts to the main plasma flow rate. The faster the main plasma flow rate, the greater the negative pressure and the more flushing fluid is drawn in. This automatically achieves a precise match between the flushing fluid flow rate and the main plasma flow rate, avoiding excessive dilution of the plasma by the flushing fluid or insufficient flow rate, which could lead to coagulation in the tubing.

[0041] When no flushing fluid bag is attached, the spring force of the spiral spring 56 keeps the rotating disk 51 in the center position. The inner side of the rotating disk 51 completely blocks and seals both sets of inlets of the three-way rotary table 55, preventing air from entering the pipeline from the external connector 54 and ensuring sterile sealing in the idle state. In use, the two flushing fluid bags A and B are connected to the two sets of external connectors 54 respectively. Initially, bag A has sufficient liquid volume and is heavier than bag B. Gravity overcomes the spring force of the spiral spring 56 and pulls the rotating disk 51 to deflect, so that the external connector 54 corresponding to bag A is precisely aligned and connected with one side of the inlet of the three-way rotary table 55, while the external connector 54 corresponding to bag B is completely misaligned and sealed with the other side of the inlet. The flushing fluid is continuously drawn into the main pipeline only from bag A.

[0042] As the flushing fluid in bag A is gradually emptied and its weight drops below that of bag B, the gravity on the side of bag B causes the rotating disk 51 to deflect in the opposite direction, automatically completing the channel switching. The external connector 54 corresponding to bag B aligns and connects with the inlet of the three-way rotary disk 55, while the connector on the side of bag A automatically shifts and closes. The entire switching process is completed automatically by gravity difference, requiring no manual operation, and the passage of the three-way rotary disk 55 remains sealed at all times, completely preventing air from entering the main channel and causing air embolism. The one-way valve 53 at the front end of the connector 52 only allows the flushing fluid to flow into the capillary tube 32 in one direction, which can completely prevent the backflow of plasma from the main channel into the flushing fluid bag and avoid cross-contamination.

[0043] The quick-release component 4 enables modular aseptic assembly and disassembly of the automatic fluid changing mechanism 5: During installation, the connector 52 is aligned with the interface on the side wall of the thin tube 32 and pushed inward. The front end of the connector 52 pushes open the elastic valve 43, opening the flushing fluid passage. After being pushed in place, the insert 41 automatically inserts downward into the slot on the outer arc surface of the connector 52 under the elastic force of the return spring 42, completing the locking and fixing of the mechanism. The sealing ring on the outer ring of the connector 52 further ensures the sealing performance at the interface, preventing leakage and external contamination. During disassembly, the insert 41 is pulled outward to compress the return spring 42, causing the lower end of the insert 41 to disengage from the slot. The entire automatic fluid changing mechanism 5 can then be pulled outward. After losing support, the valve 43 automatically springs back and closes, instantly sealing the interface of the thin tube 32, preventing contamination from contact between the inside of the tube and the outside. The entire operation requires no tools and is quick and convenient.

[0044] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A sterile flushing and control device for anticoagulation in a continuous plasma exchange tubing for severe cases, comprising a transparent tube (1), characterized in that, The front end of the transparent tube (1) is fixedly connected to a connecting tube (2), and the rear end of the transparent tube (1) is provided with a Venturi self-priming structure (3). The surface of the Venturi self-priming structure (3) is detachably installed with an automatic liquid changing mechanism (5) via a quick-release assembly (4). The Venturi self-priming structure (3) is used to match the flow rate of the flushing fluid with that of the main slurry pipeline; Quick-release assembly (4) is used to enable the modular installation and disassembly of the automatic fluid changing mechanism (5); The automatic fluid replacement mechanism (5) is used to enable the simultaneous hanging of two sets of flushing fluids, and to automatically switch after one set of flushing fluids is used up.

2. The anticoagulation sterile flushing and control device for a continuous plasma exchange tubing for severe cases according to claim 1, characterized in that, The Venturi self-priming structure (3) includes a connecting sleeve (31) fixedly connected to the rear end of the connecting tube (2). The connecting sleeve (31) is provided in two sets, and a thin tube (32) is fixedly connected between the two sets of connecting sleeves (31).

3. The anticoagulation sterile flushing and control device for a continuous plasma exchange tubing for severe cases according to claim 2, characterized in that, The two sets of connecting sleeves (31) have tapered surfaces on their opposite sides, and the diameter of the thin tube (32) is the same as the diameter of the tapered part of the connecting sleeve (31).

4. The anticoagulation sterile flushing and control device for a continuous plasma exchange tubing for severe cases according to claim 1, characterized in that, The automatic fluid changing mechanism (5) includes a three-way turntable (55), a connector plug (52) is fixedly connected to the front end of the three-way turntable (55), a one-way valve (53) is provided on the outer arc surface of the connector plug (52), a rotating disk (51) is elastically connected to the top end of the three-way turntable (55) through a spiral spring (56), and two sets of external connectors (54) are fixedly connected to the outer side wall of the rotating disk (51).

5. The anticoagulation sterile flushing and control device for a continuous plasma exchange tubing for severe cases according to claim 4, characterized in that, The three-way turntable (55) is rotatably connected to the inner sidewall of the turntable (51).

6. The anticoagulation sterile flushing and control device for a continuous plasma exchange tubing for severe cases according to claim 4, characterized in that, The outer arc surface of the three-way turntable (55) is provided with two sets of holes and slots, which match the diameter of the external connector (54).

7. The anticoagulation sterile flushing and control device for a continuous plasma exchange tubing for severe cases according to claim 4, characterized in that, One end of the spiral spring (56) is fixedly connected to the top of the inner wall of the rotating disk (51), and the other end of the spiral spring (56) is fixedly connected to the upper surface of the external connector (54).

8. The anticoagulation sterile flushing and control device for a continuous plasma exchange tubing for severe cases according to claim 1, characterized in that, The quick-release assembly (4) includes a plug (41), which is elastically connected to the inner wall of the top end of the thin tube (32) by a return spring (42). The inner side wall of the thin tube (32) is provided with a valve (43).

9. The anticoagulation sterile flushing and control device for a continuous plasma exchange tubing for severe cases according to claim 4, characterized in that, The outer arc surface of the connector (52) is provided with a slot, the connector (52) is inserted into the slot on the outer wall of the thin tube (32), and the connector (52) is inserted into the valve (43).

10. The anticoagulation sterile flushing and control device for a continuous plasma exchange tubing for severe cases according to claim 8, characterized in that, The insertion rod (41) passes through and is slidably connected to the inner wall of the outer top end of the thin tube (32). One end of the return spring (42) is fixedly connected to the surface of the insertion rod (41), and the other end of the return spring (42) is fixedly connected to the inner wall of the top end of the thin tube (32). The bottom end of the outer wall of the insertion rod (41) is inserted into the inner wall of the slot.

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