Intelligent veterinary powder dispensing system and control method thereof

Abstract

The present application relates to the technical field of veterinary medicine preparation, and relates to an intelligent veterinary medicine powder preparation system and a control method thereof, which comprises a prescription storage unit, a plurality of raw material storage containers, a batching execution unit, a weight review unit, a deviation premixing unit, a mixing processing unit, a quality inspection unit, a finished product subpackaging unit and a general control unit. The batching execution unit controls each quantitative discharging mechanism to discharge according to the selected raw material type and standard weight value of the prescription; the weight review unit weighs the actual weight value of each raw material and records the weighing deviation direction; the deviation premixing unit pre-mixes two kinds of raw materials with opposite deviation directions and the smallest sum of absolute values to form a pre-uniformized mixture when there are positive and negative deviations; the mixing processing unit mixes the premixed material and the remaining raw materials, and an internal uniformity detection probe detects the mixing uniformity online. The present application realizes intelligent production of the whole process of veterinary medicine powder, effectively improves the batching accuracy, mixing uniformity and product quality batch consistency.

Description

Technical Field

[0001] This invention relates to the field of veterinary drug preparation technology, and in particular to an intelligent veterinary drug powder preparation system and its control method. Background Technology

[0002] Veterinary drug powders are powdered preparations made from one or more veterinary drug raw materials through processes such as pulverization, sieving, and mixing. They have advantages such as rapid efficacy, convenient administration, and ease of storage and transportation, making them one of the most widely used veterinary drug dosage forms in my country's modern animal husbandry industry. In the production process of veterinary drug powders, ingredient preparation, mixing, quality inspection, and packaging are key steps determining product quality. With the rapid development of my country's veterinary drug industry, the automation and intelligence levels of veterinary drug powder production have gradually improved. However, existing production technologies still face problems such as difficulty in ensuring ingredient accuracy, outdated methods for detecting mixing uniformity, fragmented quality inspection processes, and a lack of effective information linkage and collaborative control between various production stages, which restrict further improvement in product quality. Summary of the Invention

[0003] This invention addresses the shortcomings of existing technologies by providing the following technical solution: an intelligent veterinary drug powder preparation system, comprising: A prescription storage unit is used to store multiple veterinary drug powder prescriptions, each of which includes information on the types of raw materials, the standard weight value of each raw material, and the standard parameter values ​​of the mixing process. Multiple raw material storage containers, each containing one type of raw material, each raw material storage container being provided with a discharge port, and a quantitative discharge mechanism being installed at the discharge port; The dispensing execution unit, connected to the prescription storage unit, is used to control the opening range and continuous opening time of the quantitative dispensing mechanism of each raw material storage container according to the raw material type information and the standard weight value in the selected veterinary drug powder prescription, so that each raw material storage container outputs the corresponding amount of raw material according to the standard weight value. A weight verification unit is located downstream of the batching execution unit. It is used to weigh the actual weight of each raw material output from each raw material storage container, compare the actual weight of each raw material with the corresponding standard weight, and record the weighing deviation direction of each raw material. The weighing deviation direction includes a positive deviation direction and a negative deviation direction. The positive deviation direction indicates that the actual weight is greater than the standard weight, and the negative deviation direction indicates that the actual weight is less than the standard weight. A deviation premixing unit is located downstream of the weight verification unit and connected to the weight verification unit. It is used to obtain the weighing deviation direction of each raw material from the weight verification unit and perform premixing operation according to the following rules: when there is at least one raw material with a positive deviation direction and at least another raw material with a negative deviation direction, the deviation premixing unit premixes the two raw materials with opposite weighing deviation directions and the smallest sum of the absolute values ​​of the weighing deviations before entering the mixing and processing unit to form a pre-homogenized mixture. A mixing and processing unit is located downstream of the deviation premixing unit. It is used to mix the pre-homogenized mixture and the remaining raw materials whose weight has been confirmed to be qualified by the weight verification unit to form a semi-finished veterinary drug powder. The mixing and processing unit is equipped with a uniformity detection probe to continuously detect the mixing uniformity of the semi-finished veterinary drug powder during the mixing and processing process. A quality inspection unit is located downstream of the mixing and processing unit. It is used to inspect the veterinary drug powder semi-finished product in three aspects: uniformity of effective ingredients, moisture content, and powder particle size, and generate quality inspection results. The finished product packaging unit is located downstream of the quality inspection unit and is used to package the semi-finished veterinary drug powder that has passed the quality inspection unit according to the set single package weight to form the finished veterinary drug powder. The central control unit is connected to the prescription storage unit, the ingredient execution unit, the weight verification unit, the deviation premixing unit, the mixing and processing unit, the quality inspection unit, and the finished product packaging unit, respectively. It is used to control the premixing operation of the deviation premixing unit according to the weighing deviation direction recorded by the weight verification unit, and to correct the ingredient parameters of subsequent batches according to the quality inspection results.

[0004] When the deviation premixing unit performs the premixing of two raw materials with opposite weighing deviation directions and the smallest sum of absolute weighing deviations, the duration of the premixing is a fixed value, which is less than one-tenth of the standard mixing duration of the mixing processing unit. The standard mixing duration is the standard parameter value of the mixing process in the veterinary drug powder prescription. After the pre-homogenized mixture is formed, the deviation premixing unit feeds the pre-homogenized mixture and the remaining raw materials into the mixing processing unit at the same time.

[0005] Before testing the degree of mixing uniformity, a tracer marker is pre-mixed into the mixing processing unit. The tracer marker is an inert microparticle with fluorescent properties. The particle size of the tracer marker is consistent with the particle size range of the raw material with the highest proportion in the formula. The mass proportion of the tracer marker in the semi-finished veterinary drug powder is one to five parts per thousand. The uniformity detection probe specifically includes a fluorescence excitation light source and a fluorescence intensity receiver. The fluorescence excitation light source emits excitation light to the semi-finished veterinary drug powder, and the fluorescence intensity receiver receives the fluorescence intensity signal generated by the tracer marker after it is excited. The central control unit calculates the fluorescence intensity variation coefficient based on multiple fluorescence intensity values ​​received by the fluorescence intensity receiver at different locations. When the fluorescence intensity variation coefficient is less than a preset variation coefficient threshold, the mixing uniformity is determined to meet the standard.

[0006] The tracer markers are divided into two types: a first marker and a second marker. The fluorescence emission wavelengths of the first marker and the second marker are different. During the first time period after the mixing processing unit is started, the control unit only detects the fluorescence intensity variation coefficient of the first marker. During the second time period after the mixing processing unit is started, the control unit simultaneously detects the fluorescence intensity variation coefficients of both the first marker and the second marker, and calculates the difference between the fluorescence intensity variation coefficients of the two markers. When the difference is less than a preset difference threshold and the fluorescence intensity variation coefficients of both markers are less than the preset variation coefficient threshold, the mixing uniformity is determined to meet the standard.

[0007] Before outputting the corresponding amount of raw materials according to the standard weight value, the batching unit also performs an adhesion compensation feeding operation, which specifically includes: The central control unit acquires the ambient temperature and humidity values ​​of the current production environment, and reads the adhesion coefficient of the current raw materials from the prescription storage unit; The central control unit calculates the estimated amount of container wall residue of the current raw material according to the ambient temperature value, the ambient humidity value and the adhesion coefficient in the following manner: the estimated amount of container wall residue is positively correlated with the adhesion coefficient, positively correlated with the ambient humidity value, and negatively correlated with the ambient temperature value; The central control unit superimposes the estimated amount of residue on the container wall onto the standard weight value to obtain the compensated feeding target value, and sends the compensated feeding target value to the batching execution unit. The batching execution unit controls the opening range and continuous opening time of the quantitative dispensing mechanism according to the compensated feeding target value. The actual weight value obtained by the weight verification unit is the weight of the raw material that actually falls from the raw material storage container into the weighing platform; the estimated amount of residue on the container wall is used to offset the loss of output caused by the raw material adhering to the container wall, and its value is less than five percent of the standard weight value.

[0008] The weight verification unit includes multiple weighing platforms, each weighing platform corresponding to one of the raw material storage containers, and each weighing platform operates independently. Each of the weighing platforms is equipped with a vibration device. After the raw material falls into the weighing platform, the vibration device starts running for a first preset time and then stops. The weighing platform reads the actual weight value after the vibration device stops running. The weight verification unit also records the absolute value of the deviation between the actual weight value and the standard weight value of each raw material, and sorts the absolute value of the deviation of each raw material in descending order to generate a deviation sorting list and sends it to the central control unit. The central control unit selects the raw material with the largest absolute deviation value and the raw material with the smallest absolute deviation value according to the deviation sorting list. When the weighing deviation direction of the raw material with the largest absolute deviation value is a positive deviation direction and the weighing deviation direction of the raw material with the smallest absolute deviation value is a negative deviation direction, the deviation premixing unit preferentially performs the premixing of the two raw materials. This pairing rule has a higher priority than the aforementioned general pairing rule of minimum sum of absolute values.

[0009] The quality inspection unit includes: The uniformity detection component is used to detect the uniformity of the effective components of the veterinary drug powder semi-finished product using near-infrared spectroscopy analysis to obtain uniformity detection data. A moisture detection component is used to detect the moisture content of the semi-finished veterinary drug powder using an online near-infrared moisture detection method, and to obtain moisture detection data. The fineness detection component is used to detect the powder particle size of the semi-finished veterinary drug powder using laser particle size analysis to obtain fineness detection data; The qualified determination subunit is used to compare the uniformity test data, the moisture test data and the fineness test data with the preset quality qualified standard values ​​respectively. When the uniformity test data, the moisture test data and the fineness test data all meet the corresponding quality qualified standard values, the veterinary drug powder semi-finished product is determined to be a qualified product. The material diversion subunit is connected to the qualification determination subunit. When the qualification determination subunit determines that the veterinary drug powder semi-finished product is a qualified product, the subunit transports the veterinary drug powder semi-finished product to the finished product packaging unit; when the qualification determination subunit determines that the veterinary drug powder semi-finished product is an unqualified product, the subunit transports the veterinary drug powder semi-finished product to the waste collection channel.

[0010] A control method for an intelligent veterinary drug powder preparation system includes the following steps: The prescription selection step involves selecting the target veterinary drug powder prescription to be produced from the prescription storage unit. The target veterinary drug powder prescription includes information on the types of raw materials, the standard weight value corresponding to each raw material, and the standard parameter values ​​of the mixing process. The automatic dispensing step controls the opening range and continuous opening time of the quantitative dispensing mechanism of each raw material storage container according to the raw material type information and standard weight value in the target veterinary drug powder prescription, so that each raw material storage container outputs the corresponding amount of raw material according to the standard weight value. The weight verification step involves weighing the actual weight of each raw material output from each of the raw material storage containers, comparing the actual weight of each raw material with the corresponding standard weight, and recording the weighing deviation direction of each raw material, which includes positive deviation direction and negative deviation direction. In the deviation premixing step, the weighing deviation direction of each raw material is obtained. When there is at least one raw material with a positive weighing deviation direction and at least another raw material with a negative weighing deviation direction, the two raw materials with opposite weighing deviation directions and the smallest sum of the absolute values ​​of the weighing deviations are premixed before entering the mixing processing unit to form a pre-homogenized mixture. The mixing process involves mixing the pre-homogenized mixture and the remaining raw materials whose weight has been verified to be within acceptable limits in the weight verification step to form a semi-finished veterinary drug powder. During the mixing process, the uniformity of the semi-finished veterinary drug powder is continuously monitored. The mixing process is stopped when the uniformity reaches a preset uniformity standard value. The quality inspection steps involve inspecting the semi-finished veterinary drug powder in three aspects: uniformity of effective ingredients, moisture content, and powder particle size, and generating quality inspection results. The parameter calibration step involves calibrating the batching parameters in the automatic batching step for the next production batch based on the quality inspection results. The finished product packaging step involves packaging the semi-finished veterinary drug powder that has passed the quality inspection step into individual packages according to the set weight, thus forming the finished veterinary drug powder.

[0011] In the mixing and processing step, a tracer marker is pre-mixed into the mixing and processing unit. The tracer marker is an inert microparticle with fluorescent properties. The particle size of the tracer marker is consistent with the particle size range of the raw material with the highest proportion in the formula. The mass proportion of the tracer marker in the semi-finished veterinary drug powder is one to five ten-thousandths. During the mixing process, excitation light is emitted to the semi-finished veterinary drug powder, and the fluorescence intensity signal generated by the tracer marker after excitation is received. The fluorescence intensity variation coefficient is calculated based on multiple fluorescence intensity values ​​received at different locations. When the fluorescence intensity variation coefficient is less than a preset variation coefficient threshold, the mixing uniformity is determined to meet the standard.

[0012] In the automatic batching step, before outputting the corresponding amount of raw materials according to the standard weight value, an adhesion compensation feeding operation is also performed, which includes: Obtain the ambient temperature and humidity values ​​of the current production environment, and read the adhesion coefficient of the current raw material from the prescription storage unit; The estimated amount of container wall residue of the current raw material is calculated based on the ambient temperature value, the ambient humidity value, and the adhesion coefficient. The estimated amount of container wall residue is positively correlated with the adhesion coefficient, positively correlated with the ambient humidity value, and negatively correlated with the ambient temperature value. The estimated amount of residue on the container wall is added to the standard weight value to obtain the compensated target value for feeding. The opening range and continuous opening time of the quantitative discharge mechanism are controlled according to the compensated feeding target value.

[0013] The beneficial effects of the present invention are as follows: 1. By setting up a batching execution unit, a weight verification unit, a deviation premixing unit, a mixing and processing unit, a quality inspection unit and a general control unit, the present invention realizes the intelligent production of veterinary drug powder from batching to finished product packaging, which significantly improves the batching accuracy, product uniformity and quality stability.

[0014] This invention performs an adhesion compensation feeding operation through a batching execution unit. It dynamically calculates the estimated amount of residue on the container wall based on the ambient temperature and humidity and the adhesion coefficient of the raw materials, and adds it to the standard weight value, effectively eliminating the problem of insufficient feeding caused by raw materials adhering to the container wall. Through the coordinated cooperation of the weight verification unit and the deviation premixing unit, two raw materials with opposite weighing deviation directions and the smallest sum of absolute values ​​are premixed. The local pre-homogenization reduces the concentration difference of materials entering the main mixing stage, thereby helping to improve the mixing uniformity of the final product. By introducing fluorescent tracer markers into the mixing processing unit and combining them with real-time calculation of the fluorescence intensity variation coefficient, online real-time detection of mixing uniformity was achieved, overcoming the shortcomings of offline detection lag. By integrating the detection of active ingredient uniformity, moisture content and powder particle size into the same quality inspection unit, online rapid detection of multi-dimensional quality indicators was achieved. The central control unit automatically corrects the batching parameters of subsequent batches based on the quality inspection results, effectively solving the technical problems of low batching accuracy, no compensation for weighing deviation, delayed detection of mixing uniformity, decentralized and inefficient quality inspection, and lack of intelligent control throughout the entire process in the existing technology. Detailed Implementation

[0015] The following specific examples illustrate the implementation of the present invention. Those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments, and various details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention.

[0016] The present invention provides an intelligent veterinary drug powder preparation system, including a prescription storage unit, multiple raw material storage containers, a dispensing execution unit, a weight verification unit, a deviation premixing unit, a mixing and processing unit, a quality inspection unit, a finished product packaging unit, and a central control unit.

[0017] The prescription storage unit stores prescriptions for various veterinary drug powders. Each prescription includes information on the types of raw materials, the standard weight of each raw material, and standard parameters for the mixing process. In one embodiment, the prescription storage unit uses an industrial-grade memory with non-volatile storage capabilities, such as a solid-state drive or EEPROM, to ensure the security of prescription data in the event of a power outage. In another embodiment, the prescription storage unit employs cloud storage, connecting to a central control unit via a network to enable remote updates and sharing of prescription data.

[0018] Multiple raw material storage containers are used to store different raw materials. Each raw material storage container is equipped with a discharge port, and a quantitative discharge mechanism is installed at the discharge port. The quantitative discharge mechanism adopts a screw feeder or a rotary discharge valve. Its opening range and continuous opening time are controlled by the batching execution unit, thereby accurately controlling the output of each raw material.

[0019] The dispensing execution unit is connected to the prescription storage unit and is used to control the opening range and continuous opening time of the quantitative dispensing mechanism of each raw material storage container according to the raw material type information and standard weight value in the selected veterinary drug powder prescription, so that each raw material storage container outputs the corresponding amount of raw material according to the standard weight value.

[0020] The weight verification unit is located downstream of the batching execution unit. It is used to weigh the actual weight of each raw material output from each raw material storage container, compare the actual weight of each raw material with the corresponding standard weight, and record the weighing deviation direction of each raw material. The weighing deviation direction includes positive deviation direction and negative deviation direction. The positive deviation direction indicates that the actual weight value is greater than the standard weight value, and the negative deviation direction indicates that the actual weight value is less than the standard weight value.

[0021] The deviation premixing unit is located downstream of the weight verification unit and connected to it. It is used to obtain the weighing deviation direction of each raw material from the weight verification unit and perform premixing according to preset rules. Specifically, when at least one raw material has a positive weighing deviation direction and at least another raw material has a negative weighing deviation direction, the deviation premixing unit premixes the two raw materials with opposite weighing deviation directions and the smallest sum of their absolute weighing deviations before they enter the mixing and processing unit, forming a pre-homogenized mixture.

[0022] The mixing and processing unit is located downstream of the deviation premixing unit. It is used to mix the pre-homogenized mixture with the remaining raw materials whose weight has been confirmed as qualified by the weight verification unit to form a semi-finished veterinary drug powder. The mixing and processing unit is equipped with a uniformity detection probe to continuously monitor the mixing uniformity of the semi-finished veterinary drug powder during the mixing and processing process.

[0023] The quality inspection unit is located downstream of the mixing and processing unit. It is used to inspect the quality of the semi-finished veterinary drug powder in three aspects: uniformity of effective ingredients, moisture content, and powder particle size, and to generate quality inspection results.

[0024] The finished product packaging unit is located downstream of the quality inspection unit. It is used to package the semi-finished veterinary drug powder that has passed the quality inspection unit according to the set single package weight to form the finished veterinary drug powder.

[0025] The central control unit is connected to the prescription storage unit, ingredient execution unit, weight verification unit, deviation premixing unit, mixing and processing unit, quality inspection unit, and finished product packaging unit. It controls the premixing operation of the deviation premixing unit based on the weighing deviation direction recorded by the weight verification unit, and corrects the ingredient parameters for subsequent batches based on the quality inspection results. The central control unit uses an industrial-grade programmable logic controller (PLC) or industrial computer and communicates with each unit via a data bus.

[0026] In one embodiment, the weight verification unit includes multiple weighing platforms, each corresponding to a raw material storage container, and each weighing platform operates independently. The weighing platforms employ electronic scales or loss-in-weight weighing modules, with their range and accuracy selected based on the amount of raw material being fed. For example, for raw materials with a large feeding volume, a weighing platform with a range of 0-50 kg and an accuracy of ±1 g is selected; for raw materials with a small feeding volume, a weighing platform with a range of 0-5 kg ​​and an accuracy of ±0.1 g is selected.

[0027] Each weighing platform is equipped with a vibration device. After the raw material falls onto the weighing platform, the vibration device starts and runs for a first preset time, then stops. The actual weight value is read from the weighing platform after the vibration device stops running. The function of the vibration device is to flatten and compact the raw material piled on the weighing platform, eliminating weighing errors caused by different pile shapes of the raw material. In one embodiment, the first preset time is 2 to 10 seconds, preferably 5 seconds, and the vibration device uses a vibrating motor or a pneumatic vibrator with a vibration frequency of 50Hz to 200Hz.

[0028] The weight verification unit also records the absolute value of the deviation between the actual weight value and the standard weight value of each raw material, and sorts the absolute values ​​of the deviations of each raw material in descending order, generating a deviation sorting list which is sent to the central control unit. The central control unit selects the raw material with the largest and smallest absolute deviations based on the deviation sorting list. When the weighing deviation direction of the raw material with the largest absolute deviation is positive and the weighing deviation direction of the raw material with the smallest absolute deviation is negative, the deviation premixing unit prioritizes premixing these two raw materials. This priority pairing method maximizes the local pre-homogenization effect between raw materials with large and small deviations, reducing the concentration gradient in the main mixing stage.

[0029] After obtaining the weighing deviation direction of each raw material, the deviation premixing unit performs the premixing operation according to the following rules: when there is at least one raw material with a positive weighing deviation direction and at least another raw material with a negative weighing deviation direction, the deviation premixing unit premixes the two raw materials with opposite weighing deviation directions and the smallest sum of absolute weighing deviation values ​​before entering the mixing and processing unit to form a pre-homogenized mixture.

[0030] In one embodiment, when the deviation premixing unit performs premixing on two raw materials with opposite weighing deviation directions and the smallest sum of absolute weighing deviations, the premixing duration is a fixed value, which is less than one-tenth of the standard mixing duration of the mixing processing unit. For example, when the standard mixing duration of the mixing processing unit is 30 minutes, the premixing duration is no more than 3 minutes, preferably 1 to 2 minutes. The purpose of premixing is to form a locally homogeneous mixture of the two raw materials before they enter the main mixing process, thereby making it easier to achieve overall homogeneity during the main mixing process.

[0031] After the pre-homogenized mixture is formed, the deviation premixing unit simultaneously feeds the pre-homogenized mixture and the remaining raw materials into the mixing processing unit. In one embodiment, the deviation premixing unit transports the pre-homogenized mixture to the inlet of the mixing processing unit via a conveyor belt or pneumatic conveying pipeline, while the remaining raw materials are also simultaneously fed into the mixing processing unit through their respective conveying channels.

[0032] In another embodiment, when the weighing deviation directions of all raw materials are either positive or negative, the deviation premixing unit does not perform premixing operation, and all raw materials are directly fed into the mixing processing unit for mixing processing.

[0033] In another embodiment, when there are three or more raw materials with opposite weighing deviation directions and the smallest sum of weighing deviation absolute values ​​(i.e., there are multiple sets of materials with the same sum of absolute values ​​and all of them being the smallest), the deviation premixing unit randomly selects one of these sets for premixing, or selects the two first to appear for premixing according to the order in which the raw materials are added.

[0034] The mixing unit includes a mixing container and a stirring assembly disposed within the mixing container. The stirring assembly consists of a drive motor, a stirring shaft, and stirring blades. During the mixing process, the stirring assembly rotates under the drive motor, stirring and mixing the materials within the mixing container.

[0035] The uniformity detection probe is positioned inside the mixing container. In one embodiment, the uniformity detection probe includes multiple detection points distributed at different heights and radial positions within the mixing container to achieve comprehensive detection of the mixing uniformity of the materials within the mixing container.

[0036] Before testing the uniformity of mixing, a tracer marker is pre-mixed into the mixing unit. The tracer marker is an inert microparticle with fluorescent properties, its particle size matching the range of the most abundant raw material in the formulation. The tracer marker's mass percentage in the semi-finished veterinary drug powder is 0.1% to 0.05%. For example, when the total mass of a batch of semi-finished veterinary drug powder is 100 kg, the amount of tracer marker added is 50 g to 100 g. The tracer marker is made of fluorescent dye-doped polystyrene microspheres or silica microspheres, with a particle size ranging from 1 μm to 50 μm. The inert nature of the tracer marker ensures that it does not participate in chemical reactions and does not affect the effective components and efficacy of the veterinary drug powder.

[0037] The uniformity detection probe specifically includes a fluorescence excitation source and a fluorescence intensity receiver. The fluorescence excitation source emits excitation light onto the semi-finished veterinary drug powder, and the fluorescence intensity receiver receives the fluorescence intensity signal generated after the tracer marker is excited. The fluorescence excitation source is selected based on the fluorescence characteristics of the tracer marker, using an appropriate wavelength, such as an ultraviolet LED or a laser diode. The fluorescence intensity receiver employs a photomultiplier tube or avalanche photodiode to sensitively capture weak fluorescence signals.

[0038] The central control unit calculates the coefficient of variation (CV) of fluorescence intensity based on multiple fluorescence intensity values ​​received by the fluorescence intensity receiver at different locations. The CV is the ratio of the standard deviation to the mean, used to measure the dispersion of the data. When the CV is less than a preset threshold, the central control unit determines that the mixing uniformity meets the standard. In one embodiment, the preset threshold is 5%. When the CV is less than 5%, the mixing uniformity is determined to be within the standard, and the central control unit controls the mixing unit to stop mixing. In another embodiment, for high-requirement veterinary drug powder products, the preset threshold is set to 3%.

[0039] In another embodiment, the tracer markers are of two types: a first marker and a second marker. The fluorescence emission wavelengths of the first marker and the second marker are different. For example, the first marker may be fluorescent microspheres with an emission wavelength of 520 nm (green fluorescence), and the second marker may be fluorescent microspheres with an emission wavelength of 620 nm (red fluorescence). The particle sizes of the two markers may be the same or different, but both must be consistent with the particle size range of the corresponding raw materials in the formulation.

[0040] During the first time period after the mixing and processing unit starts, the central control unit only detects the fluorescence intensity variation coefficient of the first marker. During the second time period after the mixing and processing unit starts, the central control unit simultaneously detects the fluorescence intensity variation coefficients of both the first and second markers and calculates the difference between the fluorescence intensity variation coefficients of the two markers. When this difference is less than a preset difference threshold and the fluorescence intensity variation coefficients of both markers are less than preset variation coefficient thresholds, the mixing uniformity is determined to meet the standard.

[0041] The technical significance of this dual-marker detection method lies in the following: In the initial stage of mixing (the first time period), the overall uniformity of the material is poor, and only one marker needs to be detected to determine the mixing progress. In the later stage of mixing (the second time period), by simultaneously detecting two markers and calculating their coefficient of variation difference, it is possible to more accurately determine whether the material has achieved true macroscopic and microscopic uniformity. If the difference in the coefficient of variation between the two markers is large, it indicates that the degree of mixing in different areas of the mixing container still varies, and mixing needs to continue. In one embodiment, the first time period is the first 5 to 10 minutes after the mixing process starts, and the second time period is from 10 minutes after the mixing process starts until the end of mixing. The preset difference threshold is set to 1%.

[0042] Before outputting the corresponding amount of raw materials according to the standard weight value, the batching unit also performs an adhesion compensation feeding operation.

[0043] Specifically, the central control unit acquires the current ambient temperature and humidity values ​​of the production environment. The ambient temperature value is acquired through a temperature sensor located in the ingredient mixing area, and the ambient humidity value is acquired through a humidity sensor located in the same area. The central control unit reads the adhesion coefficient of the current raw materials from the prescription storage unit. The adhesion coefficient is a physical parameter characterizing the tendency of a raw material to adhere to the container wall; different raw materials have different adhesion coefficients. For example, highly hygroscopic traditional Chinese medicine extract powders have a higher adhesion coefficient, while free-flowing mineral raw materials have a lower adhesion coefficient. The adhesion coefficient is obtained through prior laboratory testing and stored in the prescription storage unit, associated with the corresponding raw material.

[0044] The central control unit calculates the estimated amount of container wall residue from the current raw material based on ambient temperature, ambient humidity, and adhesion coefficient. Specifically, the estimated container wall residue is positively correlated with the adhesion coefficient (the higher the adhesion coefficient, the greater the estimated residue); it is negatively correlated with ambient temperature (higher temperatures result in better raw material flowability and lower estimated residue); and it is also positively correlated with ambient humidity (higher humidity results in greater residue). The proportionality coefficient is pre-calibrated based on the equipment type and container wall material, and the humidity influence coefficient is pre-calibrated based on experimental data. Ambient humidity is expressed as a percentage of relative humidity. The central control unit multiplies the product of the adhesion coefficient, the humidity influence coefficient, and the ambient humidity by one, then multiplies by the proportionality coefficient to obtain the estimated container wall residue.

[0045] The central control unit overlays the estimated residual amount on the container wall onto the standard weight value to obtain the compensated feeding target value, and then sends the compensated feeding target value to the batching execution unit. The batching execution unit controls the opening range and continuous opening time of the quantitative dispensing mechanism according to the compensated feeding target value.

[0046] The actual weight value obtained by the weight verification unit is the weight of the raw material that actually falls from the raw material storage container onto the weighing platform; the estimated amount of residue on the container wall is used to offset the loss of output caused by the raw material adhering to the container wall, and its value is less than five percent of the standard weight value, so that the compensation feeding operation will not cause the feeding amount to deviate excessively from the prescription requirements. In one embodiment, the estimated amount of residue on the container wall is one percent to three percent of the standard weight value.

[0047] This adhesive compensation feeding operation can effectively offset the problem of insufficient feeding caused by raw materials adhering to the container wall during transportation, thus improving the accuracy of batching. At the same time, since the estimated amount of residue on the container wall is related to the ambient temperature and humidity, this compensation operation can adapt to the adhesion changes under different production environment conditions, and has strong environmental adaptability.

[0048] The quality inspection unit includes a uniformity detection component, a moisture detection component, a fineness detection component, a pass / fail determination subunit, and a material diversion subunit.

[0049] The uniformity detection component is used to detect the uniformity of active ingredients in veterinary drug powder semi-finished products using near-infrared spectroscopy, obtaining uniformity detection data. Near-infrared spectroscopy is a rapid, non-destructive detection method. By analyzing the absorption spectrum of a sample in the near-infrared band (wavelength range of 780 nm to 2526 nm), the content of active ingredients in the sample can be quantitatively or semi-quantitatively determined. In one embodiment, the uniformity detection component includes a near-infrared spectrometer and a fiber optic probe. The fiber optic probe extends into the delivery pipeline of the veterinary drug powder semi-finished product to acquire spectral data online. The uniformity detection data is expressed as the relative standard deviation (RSD) of the active ingredient content; the smaller the RSD value, the more uniform the distribution of active ingredients.

[0050] The moisture detection component is used to detect the moisture content of semi-finished veterinary drug powders using online near-infrared moisture detection, obtaining moisture data. Moisture is one of the important quality indicators of veterinary drug powders; excessive moisture may lead to product clumping and spoilage, while insufficient moisture may affect the product's formability and stability. Online near-infrared moisture detection utilizes the characteristic absorption peaks of water molecules in a specific near-infrared band to quantitatively determine the moisture content in the sample. In one embodiment, the moisture detection component and the uniformity detection component share the same near-infrared spectrometer, achieving simultaneous detection of moisture and active ingredients by selecting different analytical wavelengths and mathematical models.

[0051] The fineness detection component is used to detect the particle size of semi-finished veterinary drug powders using laser particle size analysis, obtaining fineness detection data. Laser particle size analysis is based on the principle of particle scattering of laser light; particles of different sizes scatter laser light at different angles and intensities. By detecting the angular distribution of the scattered light, the particle size distribution can be calculated. In one embodiment, the fineness detection component includes a laser particle size analyzer, which continuously detects the semi-finished veterinary drug powder in the delivery pipeline through online sampling. The fineness detection data is expressed as particle size distribution characteristic values ​​such as D10, D50, and D90.

[0052] The qualification assessment subunit compares the uniformity test data, moisture test data, and fineness test data with preset quality qualification standard values. When all three data meet the corresponding quality qualification standard values, the qualification assessment subunit determines that the veterinary drug powder semi-finished product is a qualified product. The quality qualification standard values ​​are preset according to the product quality standards of veterinary drug powders (such as the relevant provisions of the Chinese Veterinary Pharmacopoeia) and stored in the storage module of the central control unit or quality inspection unit.

[0053] The material diversion subunit is connected to the qualification assessment subunit. When the qualification assessment subunit determines that the veterinary drug powder semi-finished product is qualified, the material diversion subunit transports the veterinary drug powder semi-finished product to the finished product packaging unit. When the qualification assessment subunit determines that the veterinary drug powder semi-finished product is unqualified, the material diversion subunit transports the veterinary drug powder semi-finished product to the waste collection channel. The material diversion subunit uses a three-way reversing valve or a baffle-type diverter to switch the flow direction of the material through pneumatic or electric means.

[0054] The finished product packaging unit is used to package the semi-finished veterinary drug powder, which has passed the quality inspection unit, according to the set single-package weight to form the finished veterinary drug powder. The finished product packaging unit uses an automatic powder packaging machine, including a hopper, metering device, filling device, and sealing device. The metering device uses screw metering or measuring cup metering to accurately measure according to the set single-package weight. The filling device fills the metered veterinary drug powder into packaging bags, and the sealing device heat-seals or cold-seals the packaging bags to form the finished product packaging.

[0055] In one embodiment, the finished product packaging unit further includes an online re-inspection scale for re-inspecting the weight of each package of veterinary drug powder after packaging, and rejecting products that do not meet the weight requirements. The accuracy of the online re-inspection scale is higher than that of the packaging unit; for example, the packaging unit has a measurement accuracy of ±2%, while the online re-inspection scale has an accuracy of ±0.5%.

[0056] The present invention also provides a control method for an intelligent veterinary drug powder preparation system, applicable to the intelligent veterinary drug powder preparation system described in any of the above embodiments. The method includes the following steps.

[0057] Prescription selection steps Select the target veterinary drug powder prescription to be produced from the prescription storage unit. The target veterinary drug powder prescription contains information on the types of raw materials, the standard weight value of each raw material, and the standard parameter values ​​for the mixing process. The operator selects the target prescription through a human-machine interface (such as a touch screen or host computer) connected to the central control unit. The central control unit retrieves the corresponding prescription data from the prescription storage unit based on the operator's selection.

[0058] Automatic ingredient dispensing steps Based on the information on the types of raw materials and their standard weight values ​​in the formula of the target veterinary drug powder, the opening range and continuous opening time of the quantitative dispensing mechanism of each raw material storage container are controlled to ensure that each raw material storage container outputs the corresponding amount of raw material according to the standard weight value.

[0059] In one embodiment, before outputting the corresponding amount of raw materials according to standard weight values ​​in the automatic batching step, an adhesion compensation feeding operation is also performed. The adhesion compensation feeding operation includes the following sub-steps: The system acquires the current ambient temperature and humidity values ​​of the production environment and reads the adhesion coefficient of the current raw materials from the prescription storage unit. The ambient temperature value is acquired in real time via a temperature sensor, and the ambient humidity value is acquired in real time via a humidity sensor.

[0060] The estimated amount of container wall residue from the current raw material is calculated based on ambient temperature, ambient humidity, and adhesion coefficient. The estimated container wall residue is positively correlated with the adhesion coefficient and ambient humidity, and negatively correlated with ambient temperature. The specific calculation method is described in the aforementioned formula.

[0061] The estimated amount of residue on the container wall is added to the standard weight value to obtain the compensated target value for feeding.

[0062] The opening range and continuous opening time of the quantitative discharge mechanism are controlled according to the compensated feeding target value.

[0063] By performing an adhesion compensation feeding operation, feeding deviations caused by the adhesion of raw materials to the container wall are eliminated, thereby improving the accuracy of batching.

[0064] Weight verification steps Weigh each raw material from its respective storage container, and compare the actual weight with the corresponding standard weight. Record the direction of the weighing deviation for each raw material. The direction of the weighing deviation includes positive and negative deviation. A positive deviation indicates that the actual weight is greater than the standard weight, while a negative deviation indicates that the actual weight is less than the standard weight.

[0065] In one embodiment, during the weight verification step, after the raw material falls onto the weighing platform, the vibration device is started and runs for a first preset time before stopping. The actual weight value is then read after the vibration device stops running. Vibration helps to flatten and compact the raw material on the weighing platform, improving weighing accuracy.

[0066] In another embodiment, the weight verification step further includes: recording the absolute value of the deviation between the actual weight value and the standard weight value of each raw material; sorting the absolute values ​​of the deviations of each raw material in descending order to generate a deviation sorting list; and selecting the raw material with the largest absolute value of deviation and the raw material with the smallest absolute value of deviation, prioritizing the premixing of these two raw materials in the subsequent deviation premixing step when the weighing deviation direction of the raw material with the largest absolute value of deviation is positive and the weighing deviation direction of the raw material with the smallest absolute value of deviation is negative.

[0067] Deviation premixing step The weighing deviation direction of each raw material is obtained. When there is at least one raw material with a positive weighing deviation direction and at least another raw material with a negative weighing deviation direction, the two raw materials with opposite weighing deviation directions and the smallest sum of absolute weighing deviation values ​​are pre-mixed before entering the mixing and processing unit to form a pre-homogenized mixture.

[0068] In one embodiment, in the deviation premixing step, the premixing duration is a fixed value, which is less than one-tenth of the standard mixing duration of the mixing unit. After the pre-homogenized mixture is formed, it is fed into the mixing unit simultaneously with the remaining raw materials.

[0069] Mixed processing steps The pre-homogenized mixture and the remaining raw materials, whose weights have been verified through a weight check, are mixed together to form a semi-finished veterinary drug powder. During the mixing process, the uniformity of the semi-finished veterinary drug powder is continuously monitored. Mixing is stopped when the uniformity reaches a preset standard value.

[0070] In one embodiment, during the mixing process, a tracer marker is pre-mixed into the mixing unit. The tracer marker is an inert microparticle with fluorescent properties, and its mass percentage in the semi-finished veterinary drug powder is between 0.1% and 0.05%. During the mixing process, excitation light is emitted into the semi-finished veterinary drug powder, and the fluorescence intensity signal generated by the excited tracer marker is received. The fluorescence intensity variation coefficient is calculated based on multiple fluorescence intensity values ​​received at different locations. When the fluorescence intensity variation coefficient is less than a preset variation coefficient threshold, the mixing uniformity is determined to have met the standard.

[0071] In another embodiment, the tracer markers are of two types: a first marker and a second marker. The fluorescence emission wavelengths of the first marker and the second marker are different. During a first time period after the mixing process is initiated, only the fluorescence intensity variation coefficient of the first marker is detected. During a second time period after the mixing process is initiated, the fluorescence intensity variation coefficients of both the first and second markers are detected simultaneously, and the difference between the fluorescence intensity variation coefficients of the two markers is calculated. When this difference is less than a preset difference threshold and the fluorescence intensity variation coefficients of both markers are less than a preset variation coefficient threshold, the mixing uniformity is determined to have reached the standard.

[0072] Quality inspection steps The quality of veterinary drug powder semi-finished products is tested in three aspects: uniformity of effective ingredients, moisture content, and powder particle size, and the quality test results are generated.

[0073] In one embodiment, the quality inspection steps specifically include: using near-infrared spectroscopy to detect the uniformity of the active ingredients in the veterinary drug powder semi-finished product, obtaining uniformity test data; using online near-infrared moisture detection to detect the moisture content of the veterinary drug powder semi-finished product, obtaining moisture test data; and using laser particle size analysis to detect the powder particle size of the veterinary drug powder semi-finished product, obtaining fineness test data. The uniformity test data, moisture test data, and fineness test data are compared with preset quality qualification standard values. When all three data meet the corresponding quality qualification standard values, the veterinary drug powder semi-finished product is determined to be a qualified product. When the veterinary drug powder semi-finished product is determined to be a qualified product, it is transported to the finished product packaging unit; when the veterinary drug powder semi-finished product is determined to be a non-qualified product, it is transported to the waste collection channel.

[0074] Parameter calibration steps The batching parameters in the automated batching process for the next production batch are corrected based on the quality inspection results. For example, if the quality inspection results show that the content of the active ingredient in a batch of veterinary drug powder semi-finished product is low, the central control unit determines that there may be a negative deviation in the actual feeding of the raw material corresponding to the active ingredient. Therefore, the target feeding value of the raw material is appropriately increased in the automatic batching process for the next batch after compensation. If the test results show that the moisture content exceeds the standard, the dehumidification parameters of the production environment are adjusted or the drying time of the mixing stage is extended in the next batch. If the test results show that the powder particle size does not meet the standard, the grinding parameters are fed back to the preceding grinding process for adjustment. Specifically, the central control unit calculates the correction amount of the batching parameters based on the deviation between the quality inspection results and the standard value, and applies the correction amount to the feeding control of the next batch. Through this closed-loop correction method, continuous improvement and stable control of production quality are achieved.

[0075] Finished product packaging steps The semi-finished veterinary drug powder, which has passed the quality inspection process, is packaged according to the set weight per package to form the finished veterinary drug powder. The packaged finished products then undergo further packaging, labeling, and warehousing.

[0076] System Workflow Example The complete workflow of the system of the present invention will be illustrated below with a specific production example.

[0077] Suppose that a batch of veterinary drug powder containing three components, raw material A, raw material B, and raw material C, needs to be produced. The standard weight values ​​of the three raw materials in the prescription are as follows: raw material A 10.00 kg, raw material B 5.00 kg, and raw material C 2.00 kg.

[0078] First, the operator selects the target prescription through the human-machine interface, and the central control unit retrieves the prescription data from the prescription storage unit.

[0079] The ingredient dispensing unit controls the dispensing mechanisms for raw materials A, B, and C to feed them according to the prescription data. During the dispensing process, the central control unit acquires the current ambient temperature (e.g., 25°C) and humidity (e.g., 60%RH), and reads the adhesion coefficients of the three raw materials. Assuming that raw material A has a high adhesion coefficient, the estimated residue on the container wall is calculated to be 0.20 kg, and the compensated dispensing target value is 10.20 kg; the estimated residue on the container wall for raw material B is 0.05 kg, and the compensated dispensing target value is 5.05 kg; the estimated residue on the container wall for raw material C is 0.02 kg, and the compensated dispensing target value is 2.02 kg. The ingredient dispensing unit controls each dispensing mechanism according to the compensated dispensing target values.

[0080] Each raw material is placed onto its corresponding weighing platform. The vibration device starts running for 5 seconds and then stops. The weighing platform reads the actual weight value. Assume the actual weighing results are: Raw material A 10.02kg (deviation +0.02kg, positive deviation), Raw material B 4.97kg (deviation -0.03kg, negative deviation), Raw material C 2.005kg (deviation +0.005kg, positive deviation).

[0081] The weight verification unit records the direction of the weighing deviation for each raw material and sorts them by absolute value: Raw material B (0.03 kg), Raw material A (0.02 kg), and Raw material C (0.005 kg). Raw material B, with the largest absolute deviation value, represents the negative deviation direction, while raw material C, with the smallest absolute deviation value, represents the positive deviation direction. Since their deviation directions are opposite, they satisfy the priority pairing condition. Therefore, the deviation premixing unit preferentially selects raw material B and raw material C for premixing to form a pre-homogenized mixture; this pairing also conforms to the general rule of opposite weighing deviation directions and the smallest sum of absolute deviation values. After premixing for 2 minutes, the pre-homogenized mixture and raw material A are simultaneously fed into the mixing processing unit.

[0082] The mixing unit initiates the mixing process, and the uniformity detection probe simultaneously starts operating. The tracer marker is pre-mixed into the mixing container. During the first 8 minutes of mixing (the first time period), the central control unit only detects the fluorescence intensity variation coefficient of the first marker; after 8 minutes (the second time period), the central control unit simultaneously detects the fluorescence intensity variation coefficients of both the first and second markers. When the variation coefficients of both markers are less than 5% and the difference between them is less than 1%, the central control unit determines that the mixing uniformity has reached the standard and controls the mixing unit to stop the mixing process.

[0083] After mixing, the semi-finished veterinary drug powder enters the quality inspection unit. The uniformity detection component uses near-infrared spectroscopy to analyze the uniformity of the active ingredients, the moisture detection component detects the moisture content, and the fineness detection component detects the powder particle size. When all test data meet the preset quality standards, the qualification subunit determines the product is qualified, and the material diversion subunit transports the product to the finished product packaging unit for further packaging.

[0084] Based on the quality inspection results of this production run, the central control unit adjusts the ingredient parameters for the next batch. For example, if the content of the active ingredient is found to be slightly lower than the standard value, the corresponding raw material will be appropriately increased to compensate for the lower target value in the next batch.

[0085] The above embodiments are merely illustrative of the technical solutions of the present invention and are not intended to limit it. Anyone skilled in the art can modify or alter the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or alterations made by those skilled in the art without departing from the spirit and technical concept disclosed in the present invention should still be covered by the claims of the present invention.

Claims

1. An intelligent veterinary drug powder preparation system, characterized in that, include: The prescription storage unit stores prescriptions containing information on the types of raw materials, standard weights, and mixing parameters. Multiple raw material storage containers, each equipped with a discharge port with a quantitative discharge mechanism; The dispensing execution unit is connected to the prescription storage unit and controls each dispensing mechanism to dispense ingredients according to the standard weight based on the prescription. The weight verification unit, located downstream of the batching execution unit, weighs the actual weight of each raw material and compares it with the standard weight, recording the positive or negative deviation. The deviation premixing unit is connected to the weight verification unit to obtain the deviation direction. If both positive and negative deviations exist, the two raw materials with opposite deviation directions and the smallest sum of absolute values ​​are premixed into a pre-homogenized material. The mixing and processing unit, located downstream of the deviation premixing unit, mixes the pre-homogenized material with the remaining raw materials to form a semi-finished product. Its built-in uniformity detection probe detects the mixing uniformity online. The quality inspection unit, located downstream of the mixing and processing unit, inspects the uniformity of the effective components, moisture content, and particle size of the semi-finished product and generates inspection results. The finished product packaging unit, located downstream of the quality inspection unit, packages qualified semi-finished products into finished products according to their individual package weights. The central control unit connects all units, controls the premixing operation according to the direction of deviation, and corrects subsequent batching parameters based on test results.

2. The intelligent veterinary drug powder preparation system according to claim 1, characterized in that, When the deviation premixing unit performs the premixing of two raw materials with opposite weighing deviation directions and the smallest sum of absolute weighing deviations, the duration of the premixing is a fixed value, which is less than one-tenth of the standard mixing duration of the mixing processing unit. The standard mixing duration is the standard parameter value of the mixing process in the veterinary drug powder prescription. After the pre-homogenized mixture is formed, the deviation premixing unit feeds the pre-homogenized mixture and the remaining raw materials into the mixing processing unit at the same time.

3. The intelligent veterinary drug powder preparation system according to claim 1, characterized in that, Before testing the degree of mixing uniformity, a tracer marker is pre-mixed into the mixing processing unit. The tracer marker is an inert microparticle with fluorescent properties. The particle size of the tracer marker is consistent with the particle size range of the raw material with the highest proportion in the formula. The mass proportion of the tracer marker in the semi-finished veterinary drug powder is one to five parts per thousand. The uniformity detection probe specifically includes a fluorescence excitation light source and a fluorescence intensity receiver. The fluorescence excitation light source emits excitation light to the semi-finished veterinary drug powder, and the fluorescence intensity receiver receives the fluorescence intensity signal generated by the tracer marker after it is excited. The central control unit calculates the fluorescence intensity variation coefficient based on multiple fluorescence intensity values ​​received by the fluorescence intensity receiver at different locations. When the fluorescence intensity variation coefficient is less than a preset variation coefficient threshold, the mixing uniformity is determined to meet the standard.

4. The intelligent veterinary drug powder preparation system according to claim 3, characterized in that, The tracer markers are divided into two types: a first marker and a second marker. The fluorescence emission wavelength of the first marker is different from that of the second marker. During the first time period after the start of the hybrid processing unit, the control unit only detects the fluorescence intensity variation coefficient of the first marker. During the second time period after the start of the hybrid processing unit, the control unit simultaneously detects the fluorescence intensity variation coefficients of both the first marker and the second marker, and calculates the difference between the fluorescence intensity variation coefficients of the two markers. When the difference is less than a preset difference threshold and the fluorescence intensity variation coefficients of both markers are less than the preset variation coefficient threshold, the mixing uniformity is determined to meet the standard.

5. The intelligent veterinary drug powder preparation system according to claim 1, characterized in that, Before outputting the corresponding amount of raw materials according to the standard weight value, the batching unit also performs an adhesion compensation feeding operation, which specifically includes: The central control unit acquires the ambient temperature and humidity values ​​of the current production environment, and reads the adhesion coefficient of the current raw materials from the prescription storage unit; The central control unit calculates the estimated amount of container wall residue of the current raw material according to the ambient temperature value, the ambient humidity value and the adhesion coefficient in the following manner: the estimated amount of container wall residue is positively correlated with the adhesion coefficient, positively correlated with the ambient humidity value, and negatively correlated with the ambient temperature value; The central control unit superimposes the estimated amount of residue on the container wall onto the standard weight value to obtain the compensated feeding target value, and sends the compensated feeding target value to the batching execution unit. The batching execution unit controls the opening range and continuous opening time of the quantitative dispensing mechanism according to the compensated feeding target value. The actual weight value obtained by the weight verification unit is the weight of the raw material that actually falls from the raw material storage container into the weighing platform; the estimated amount of residue on the container wall is used to offset the loss of output caused by the raw material adhering to the container wall, and its value is less than five percent of the standard weight value.

6. The intelligent veterinary drug powder preparation system according to claim 1, characterized in that, The weight verification unit includes multiple weighing platforms, each weighing platform corresponding to one of the raw material storage containers, and each weighing platform operates independently. Each of the weighing platforms is equipped with a vibration device. After the raw material falls into the weighing platform, the vibration device starts running for a first preset time and then stops. The weighing platform reads the actual weight value after the vibration device stops running. The weight verification unit also records the absolute value of the deviation between the actual weight value and the standard weight value of each raw material, and sorts the absolute value of the deviation of each raw material in descending order to generate a deviation sorting list and sends it to the central control unit. The central control unit selects the raw material with the largest absolute deviation value and the raw material with the smallest absolute deviation value according to the deviation sorting list. When the weighing deviation direction of the raw material with the largest absolute deviation value is a positive deviation direction and the weighing deviation direction of the raw material with the smallest absolute deviation value is a negative deviation direction, the deviation premixing unit preferentially performs the premixing of the two raw materials. This pairing rule has a higher priority than the aforementioned general pairing rule of minimum sum of absolute values.

7. The intelligent veterinary drug powder preparation system according to claim 1, characterized in that, The quality inspection unit includes: The uniformity detection component is used to detect the uniformity of the effective components of the veterinary drug powder semi-finished product using near-infrared spectroscopy analysis to obtain uniformity detection data. A moisture detection component is used to detect the moisture content of the semi-finished veterinary drug powder using an online near-infrared moisture detection method, and to obtain moisture detection data. The fineness detection component is used to detect the powder particle size of the semi-finished veterinary drug powder using laser particle size analysis to obtain fineness detection data; The qualified determination subunit is used to compare the uniformity test data, the moisture test data and the fineness test data with the preset quality qualified standard values ​​respectively. When the uniformity test data, the moisture test data and the fineness test data all meet the corresponding quality qualified standard values, the veterinary drug powder semi-finished product is determined to be a qualified product. The material diversion subunit is connected to the qualification determination subunit. When the qualification determination subunit determines that the veterinary drug powder semi-finished product is a qualified product, the subunit transports the veterinary drug powder semi-finished product to the finished product packaging unit; when the qualification determination subunit determines that the veterinary drug powder semi-finished product is an unqualified product, the subunit transports the veterinary drug powder semi-finished product to the waste collection channel.

8. A control method for an intelligent veterinary drug powder preparation system, applied to the intelligent veterinary drug powder preparation system as described in any one of claims 1 to 7, characterized in that, Includes the following steps: The prescription selection step involves selecting the target veterinary drug powder prescription to be produced from the prescription storage unit. The target veterinary drug powder prescription includes information on the types of raw materials, the standard weight value corresponding to each raw material, and the standard parameter values ​​of the mixing process. The automatic dispensing step controls the opening range and continuous opening time of the quantitative dispensing mechanism of each raw material storage container according to the raw material type information and standard weight value in the target veterinary drug powder prescription, so that each raw material storage container outputs the corresponding amount of raw material according to the standard weight value. The weight verification step involves weighing the actual weight of each raw material output from each of the raw material storage containers, comparing the actual weight of each raw material with the corresponding standard weight, and recording the weighing deviation direction of each raw material, which includes positive deviation direction and negative deviation direction. In the deviation premixing step, the weighing deviation direction of each raw material is obtained. When there is at least one raw material with a positive weighing deviation direction and at least another raw material with a negative weighing deviation direction, the two raw materials with opposite weighing deviation directions and the smallest sum of the absolute values ​​of the weighing deviations are premixed before entering the mixing processing unit to form a pre-homogenized mixture. The mixing process involves mixing the pre-homogenized mixture and the remaining raw materials whose weight has been verified to be within acceptable limits in the weight verification step to form a semi-finished veterinary drug powder. During the mixing process, the uniformity of the semi-finished veterinary drug powder is continuously monitored. The mixing process is stopped when the uniformity reaches a preset uniformity standard value. The quality inspection steps involve inspecting the semi-finished veterinary drug powder in three aspects: uniformity of effective ingredients, moisture content, and powder particle size, and generating quality inspection results. The parameter calibration step involves calibrating the batching parameters in the automatic batching step for the next production batch based on the quality inspection results. The finished product packaging step involves packaging the semi-finished veterinary drug powder that has passed the quality inspection step into individual packages according to the set weight, thus forming the finished veterinary drug powder.

9. The control method for the intelligent veterinary drug powder preparation system according to claim 8, characterized in that, In the mixing and processing step, a tracer marker is pre-mixed into the mixing and processing unit. The tracer marker is an inert microparticle with fluorescent properties. The particle size of the tracer marker is consistent with the particle size range of the raw material with the highest proportion in the formula. The mass proportion of the tracer marker in the semi-finished veterinary drug powder is one to five ten-thousandths. During the mixing process, excitation light is emitted to the semi-finished veterinary drug powder, and the fluorescence intensity signal generated by the tracer marker after excitation is received. The fluorescence intensity variation coefficient is calculated based on multiple fluorescence intensity values ​​received at different locations. When the fluorescence intensity variation coefficient is less than a preset variation coefficient threshold, the mixing uniformity is determined to meet the standard.

10. The control method for the intelligent veterinary drug powder preparation system according to claim 8, characterized in that, In the automatic batching step, before outputting the corresponding amount of raw materials according to the standard weight value, an adhesion compensation feeding operation is also performed, which includes: Obtain the ambient temperature and humidity values ​​of the current production environment, and read the adhesion coefficient of the current raw material from the prescription storage unit; The estimated amount of container wall residue of the current raw material is calculated based on the ambient temperature value, the ambient humidity value, and the adhesion coefficient. The estimated amount of container wall residue is positively correlated with the adhesion coefficient, positively correlated with the ambient humidity value, and negatively correlated with the ambient temperature value. The estimated amount of residue on the container wall is added to the standard weight value to obtain the compensated target value for feeding. The opening range and continuous opening time of the quantitative discharge mechanism are controlled according to the compensated feeding target value.