A traditional Chinese medicine composition for invigorating the spleen and removing turbidity and a preparation method thereof

Abstract

The application discloses a traditional Chinese medicine composition for invigorating the spleen and removing turbidity and a preparation method thereof, and relates to the field of traditional Chinese medicines. The traditional Chinese medicine composition for invigorating the spleen and removing turbidity is prepared from the following raw medicinal materials in parts by weight: 20-30 parts of Baizhu, 10-15 parts of Renshen, 20-30 parts of Fuling, 10-20 parts of Jisheng, 10-12 parts of Houpu, 9-12 parts of Jiangbanxia, 3-10 parts of Huanglian, 6-10 parts of Ganjiang, 10-20 parts of Helve, 10-15 parts of Yueshicao and 6-10 parts of Zhigancao. The application has the functions of invigorating the spleen and replenishing qi to ascend clear, promoting qi to move the stomach to descend turbidity, and makes the ascending, descending, intake, and dryness and dampness of the spleen and stomach balanced, is used for treating cold and heat mutual knotting, ascending and descending failure, and damp turbidity internal retention caused by the spleen deficiency and abnormal transportation, and has a remarkable clinical curative effect.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine, specifically to a traditional Chinese medicine composition for strengthening the spleen and resolving turbidity, and its preparation method. Background Technology

[0002] The paper "Exploring the Theoretical Basis of Traditional Chinese Medicine's Treatment of Metabolic Fatty Liver Disease (MAFLD) from the Perspective of Spleen and Stomach Based on Gut Microbiota," published in the 2024 Journal of Yunnan University of Traditional Chinese Medicine, points out that while the pathogenesis of MAFLD is located in the liver, its root cause lies in the spleen and stomach. The spleen and stomach act as an axis, coordinating the middle jiao (middle burner). The stomach is responsible for receiving and digesting food, while the spleen is responsible for transforming and transporting fluids. The stomach governs the descent of turbid fluids, while the spleen governs the ascent of clear fluids. The spleen and stomach are the pivot of the body's qi (vital energy) movement. When the spleen fails to function properly, its function of transforming and transporting the essence of food is impaired. The spleen fails to distribute this essence, and instead, the essence of food fails to be transformed into qi and blood, leading to dampness and phlegm accumulation. This internal generation of phlegm and dampness hinders blood circulation, causing stagnation and ultimately impairing the liver's function of regulating qi. MAFLD results from impaired spleen function in transformation and transportation and the spleen's function in distributing essence, leading to imbalances in the ascending and descending qi of the spleen and stomach. This imbalance results in the accumulation of dampness and the generation of phlegm, which in turn obstructs the liver meridians. The spleen and stomach are closely related to the body's qi movement; imbalances in their qi movement are a major cause of MAFLD, persisting throughout the entire course of the disease.

[0003] The article "Professor Yao Naili's Experience in Treating Metabolic Fatty Liver Disease Based on Qi Transformation Theory" was published in the 2022 issue of the Chinese Journal of Traditional Chinese Medicine. Professor Yao advocates Li Dongyuan's theory that "internal injury to the spleen and stomach leads to the development of a hundred diseases," as stated in "Treatise on the Spleen and Stomach: On the Transmission and Transformation of Deficiency and Excess in the Spleen and Stomach": "The abundance of primordial qi depends on the undamaged qi of the spleen and stomach, which then nourishes the primordial qi... If the qi of the spleen and stomach is damaged, the primordial qi cannot be replenished, and this is the source of all diseases." Professor Yao believes that spleen and stomach deficiency is the core pathogenesis of MAFLD, with the key pathogenesis being spleen and stomach weakness leading to the internal generation of phlegm and dampness. In the treatment process, Professor Yao emphasizes restoring the qi transformation function of the liver, spleen, and kidneys. Spleen deficiency leads to impaired transportation and transformation, failing to regulate water metabolism, resulting in abnormal distribution of water essence, causing stagnation of yin evil internally. If the spleen fails to ascend, stagnation occurs; if the spleen does not move, stagnation also occurs. Summary of the Invention

[0004] The purpose of this invention is to provide a traditional Chinese medicine composition for strengthening the spleen and eliminating turbidity, and its preparation method, so as to achieve the effect of strengthening the spleen and eliminating turbidity.

[0005] To achieve the above objectives, the present invention provides the following technical solution:

[0006] A traditional Chinese medicine composition for invigorating the spleen and resolving turbidity, the composition being made from the following raw materials in parts by weight: Atractylodes macrocephala 20-30 parts, Ginseng 10-15 parts, Poria cocos 20-30 parts, Citrus aurantium 10-20 parts, Magnolia officinalis 10-12 parts, Pinellia ternata 9-12 parts, Coptis chinensis 3-10 parts, Zingiber officinale 6-10 parts, Nelumbo nucifera leaf 10-20 parts, Evening primrose 10-15 parts, and Glycyrrhiza uralensis 6-10 parts.

[0007] Furthermore, the Atractylodes macrocephala is stir-fried with wheat bran, and the Citrus aurantium is stir-fried with wheat bran.

[0008] Furthermore, the traditional Chinese medicine composition is preferably made from the following raw materials in parts by weight: 25 parts of Atractylodes macrocephala, 13 parts of ginseng, 25 parts of Poria cocos, 15 parts of Citrus aurantium, 11 parts of Magnolia officinalis, 11 parts of Pinellia ternata, 7 parts of Coptis chinensis, 8 parts of dried ginger, 5 parts of lotus leaf, 13 parts of evening primrose, and 8 parts of prepared licorice root.

[0009] Furthermore, the preparation method includes the following steps: weighing each raw material, pretreatment, extraction, and concentration.

[0010] Weigh each raw material: Weigh the following ingredients in the composition: Atractylodes macrocephala, ginseng, Poria cocos, Citrus aurantium, Magnolia officinalis, Pinellia ternata, Coptis chinensis, dried ginger, Nelumbo nucifera leaf, evening primrose, and prepared licorice root.

[0011] Pre-processing: Atractylodes macrocephala and Citrus aurantium are stir-fried with wheat bran, while the remaining medicinal materials are cleaned and cut.

[0012] Extraction: Add 8-10 times the amount of water to the processed medicinal materials, decoct 1-3 times, 0.5-0.75 hours each time, and combine the decoctions;

[0013] Concentration: Simmer the decoction over low heat until it becomes a thick paste.

[0014] Second aspect of the invention:

[0015] Use of traditional Chinese medicine compositions in the preparation of drugs for strengthening the spleen and eliminating turbidity.

[0016] Furthermore, the drug has the effect of strengthening the spleen and clearing away turbidity.

[0017] Furthermore, the drug is in solid, semi-solid, or liquid form.

[0018] Further, the drug is a decoction, granules, ointment, tablet, capsule, oral liquid, powder, or prepared slices; preferably, the drug is a decoction or granules.

[0019] Third aspect of the invention:

[0020] The drug of this invention can be prepared using conventional methods in the art, with or without pharmaceutically acceptable excipients. As long as the raw materials of traditional Chinese medicine are in the above-mentioned weight proportions, any variations in the preparation method fall within the scope of this invention. The drug form includes, but is not limited to, solid, semi-solid, or liquid forms; specifically, it includes, but is not limited to, decoctions, granules, pastes, tablets, capsules, oral liquids, powders, or processed medicinal slices.

[0021] Furthermore, this includes the extraction of traditional Chinese medicine compositions, such as decoction extraction, reflux extraction, and ultrasonic extraction.

[0022] Further steps include weighing each active pharmaceutical ingredient, pretreatment, extraction (with water and / or alcohol), and concentration.

[0023] Further steps include weighing each raw material, crushing, extracting, and concentrating it.

[0024] Furthermore, the extraction method is decoction, the extraction solvent is water, the number of decoctions is 1-3, and the decoction time for each decoction is 0.5-0.75 hours.

[0025] Furthermore, water extraction is used.

[0026] The beneficial effects of this invention are as follows: This application has the functions of strengthening the spleen and replenishing qi, promoting the upward movement of clear qi, regulating qi and harmonizing the stomach, and reducing turbidity. In this formula, ginseng, poria, atractylodes macrocephala, and prepared licorice root replenish qi and strengthen the spleen; lotus leaf strengthens the spleen and raises yang; immature bitter orange and magnolia bark regulate qi and eliminate fullness; coptis chinensis, bitter and cold, clears heat and dries dampness to eliminate fullness; pinellia ternata, pungent and warm, disperses stagnation and harmonizes the stomach; a small amount of dried ginger, pungent and hot, warms the middle and dispels cold. The three herbs work together, opening up the qi with their pungent and descending properties, regulating the qi mechanism. Evening primrose, a local specialty of Xinjiang, has the effect of removing dampness and eliminating turbidity. The entire formula strengthens the spleen and replenishes qi, promotes the upward movement of clear qi, regulates qi and harmonizes the stomach, and reduces turbidity, thus achieving a balance in the ascending and descending, entering and exiting, digesting and transforming, and drying and dampness-reducing functions of the spleen and stomach. It is used for MAFLD caused by spleen deficiency and impaired transportation and transformation, resulting in the mutual binding of cold and heat, dysfunction of ascending and descending, and internal retention of dampness and turbidity, with significant clinical efficacy.

[0027] The above description is merely an overview of the technical solution of the present invention. In order to better understand the technical means of the present invention and to implement it in accordance with the contents of the specification, the preferred embodiments of the present invention are described in detail below. Detailed Implementation

[0028] The technical solutions of the present invention will now be clearly and completely described. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0029] In the description of this invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating orientation or positional relationships, are based on the shown orientation or positional relationships and are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0030] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0031] Furthermore, the technical features involved in the different embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other.

[0032] A preferred embodiment of this application shows a traditional Chinese medicine composition for strengthening the spleen and resolving turbidity. The traditional Chinese medicine composition is made from the following raw materials in parts by weight: 20-30 parts of Atractylodes macrocephala, 10-15 parts of ginseng, 20-30 parts of Poria cocos, 10-20 parts of Citrus aurantium, 10-12 parts of Magnolia officinalis, 9-12 parts of Pinellia ternata, 3-10 parts of Coptis chinensis, 6-10 parts of dried ginger, 10-20 parts of Nelumbo nucifera leaf, 10-15 parts of evening primrose, and 6-10 parts of prepared licorice root.

[0033] The Atractylodes macrocephala mentioned is stir-fried with wheat bran, and the Citrus aurantium mentioned is stir-fried with wheat bran.

[0034] The traditional Chinese medicine composition is preferably made from the following raw materials in parts by weight: 25 parts of Atractylodes macrocephala, 13 parts of ginseng, 25 parts of Poria cocos, 15 parts of Citrus aurantium, 11 parts of Magnolia officinalis, 11 parts of Pinellia ternata, 7 parts of Coptis chinensis, 8 parts of dried ginger, 5 parts of lotus leaf, 13 parts of evening primrose, and 8 parts of prepared licorice root.

[0035] The preparation method includes the following steps: weighing each raw material, pretreatment, extraction, and concentration.

[0036] Weigh each raw material: Weigh the following ingredients in the composition: Atractylodes macrocephala, ginseng, Poria cocos, Citrus aurantium, Magnolia officinalis, Pinellia ternata, Coptis chinensis, dried ginger, Nelumbo nucifera leaf, evening primrose, and prepared licorice root.

[0037] Pre-processing: Atractylodes macrocephala and Citrus aurantium are stir-fried with wheat bran, while the remaining medicinal materials are cleaned and cut.

[0038] Extraction: Add 8-10 times the amount of water to the processed medicinal materials, decoct 1-3 times, 0.5-0.75 hours each time, and combine the decoctions;

[0039] Concentration: Simmer the decoction over low heat until it becomes a thick paste.

[0040] Second aspect of the invention:

[0041] Use of traditional Chinese medicine compositions in the preparation of drugs for strengthening the spleen and eliminating turbidity.

[0042] The medicine has the effect of strengthening the spleen and clearing away turbidity.

[0043] The drug is in solid, semi-solid, or liquid form.

[0044] The drug is a decoction, granules, ointment, tablet, capsule, oral liquid, powder, or prepared slices; preferably, the drug is a decoction or granules.

[0045] Third aspect of the invention:

[0046] The drug of this invention can be prepared using conventional methods in the art, with or without pharmaceutically acceptable excipients. As long as the raw materials of traditional Chinese medicine are in the above-mentioned weight proportions, any variations in the preparation method fall within the scope of this invention. The drug form includes, but is not limited to, solid, semi-solid, or liquid forms; specifically, it includes, but is not limited to, decoctions, granules, pastes, tablets, capsules, oral liquids, powders, or processed medicinal slices.

[0047] This includes the extraction of traditional Chinese medicine compositions, such as decoction extraction, reflux extraction, and ultrasonic extraction.

[0048] This includes weighing each active pharmaceutical ingredient, pretreatment, extraction (with water and / or alcohol), and concentration.

[0049] This includes weighing the raw materials, crushing, extracting, and concentrating them.

[0050] The extraction method is decoction, the extraction solvent is water, the number of decoctions is 1-3, and the decoction time is 0.5-0.75 hours each time.

[0051] Water extraction is used.

[0052] The formula of the traditional Chinese medicine composition of this invention is explained as follows:

[0053] The formula contains ginseng, poria, atractylodes macrocephala, and prepared licorice root to invigorate qi and strengthen the spleen; lotus leaf to invigorate the spleen and raise yang; immature bitter orange and magnolia bark to regulate qi, eliminate stagnation and fullness; coptis chinensis, bitter and cold to clear heat and dry dampness to eliminate stagnation; pinellia ternata, pungent and warm to disperse stagnation and harmonize the stomach; and a small amount of dried ginger, pungent and hot to warm the middle and dispel cold. The three herbs work together to open up the qi and descend the cold, regulating the qi mechanism. Evening primrose is a local Chinese herb from Xinjiang, which has the effect of removing dampness and clearing turbidity.

[0054] Atractylodes macrocephala: Bitter and sweet in taste, warm in nature, and belongs to the spleen and stomach meridians. It has various effects, including strengthening the spleen and replenishing qi, drying dampness and promoting diuresis, stopping sweating, and calming the fetus. It is commonly used to treat symptoms such as loss of appetite, abdominal distension and diarrhea caused by spleen deficiency, dizziness, spontaneous sweating, edema, and threatened abortion caused by phlegm retention.

[0055] Modern scientific research has found that the rhizome of Atractylodis Macrocephalae Rhizoma is rich in volatile oil, and its main components include atractylon, atractylol, atractylenolide A and B, 3-β-acetoxyatractylon, 3-β-hydroxyatractylon and the like. These components endow Atractylodis Macrocephalae Rhizoma with a lasting diuretic effect and hypoglycemic function. In addition, Atractylodis Macrocephalae Rhizoma can increase the decreased white blood cell count caused by chemotherapy and physical therapy. Its decoction can also protect the liver, prevent the reduction of liver glycogen caused by carbon tetrachloride, and have the effects of strengthening the physique and resisting blood coagulation.

[0056] Ginseng: Sweet in tonifying, slightly warm in nature, slightly bitter without purgation, with strong medicinal power, it is an essential herb for tonifying qi and strengthening the body. It is good at heavily tonifying primordial qi to treat qi collapse due to qi deficiency; it is also good at tonifying the qi of the spleen and lung to treat various syndromes of spleen-lung qi deficiency; it can further tonify qi to promote the production of body fluids, soothe the mind and improve intelligence, and treat thirst due to fluid impairment, wasting-thirst, restlessness of the mind, palpitation and amnesia and the like.

[0057] It mainly contains various ginsenosides of the panaxadiol type, panaxatriol type and oleanolic acid type, and also contains components such as ginseng polysaccharides, polypeptide compounds, ester compounds, sesquiterpene alcohol compounds, alkyne compounds, amino acids, organic acids, alkaloids, vitamins, enzymes, flavonoids, volatile oil, trace elements and the like, and has the efficacies of heavily tonifying primordial qi, restoring pulse to rescue from collapse, tonifying the spleen and benefiting the lung, generating body fluids and nourishing blood, and soothing the mind and improving intelligence.

[0058] Modern scientific research has found that ginseng can resist shock, strengthen the heart, lower blood pressure, resist hypoxia and protect the myocardium, improve hemorheology and resist thrombosis; it can excite the pituitary-adrenocortical system, resist stress, improve immune function, enhance hematopoietic function, regulate the balance between the excitation and inhibition processes of the central nervous system, promote learning and memory, and resist fatigue; it can promote the synthesis of protein, RNA and DNA; it can regulate cholesterol metabolism, lower blood lipid and lower blood glucose; it has gonadotropin-like effects; it also has anti-inflammatory, anti-allergic, antidiuretic, anti-tumor, anti-ulcer, anti-radiation, liver-protective, antioxidant and other effects.

[0059] Poria: It has the efficacies of promoting diuresis and excreting dampness, invigorating the spleen, and tranquilizing the mind. It is indicated for edema, phlegm-fluid retention, spleen-deficiency diarrhea, palpitation and insomnia. It contains β-pachyman, accounting for about 93% of the dry weight, and also contains pachymic acid, tumulosic acid, eburicoic acid, ergosterol, protein, fat, lecithin, adenine and the like.

[0060] Aurantii Fructus Immaturus: It tastes bitter, pungent and sour, is slightly cold in nature, and acts on the spleen and stomach meridians. It has the efficacies of breaking qi to resolve food stagnation, resolving phlegm and relieving stuffiness, and is indicated for internal stagnation of accumulated stagnant substances, stuffiness and fullness with distending pain, tenesmus in dysentery, unsmooth defecation, phlegm stagnation and qi obstruction, chest impediment, chest pain with hard focal distension, and visceroptosis. It mainly contains flavonoid components (such as hesperidin, neohesperidin, nobiletin and the like), volatile oil (such as d-limonene, citral, dextro-linalool and the like), alkaloid components (such as synephrine and the like) as well as terpenoid components (such as limonin and the like).

[0061] Magnolia officinalis: It has the effects of warming the middle jiao (spleen and stomach), regulating qi, drying dampness, and resolving phlegm. It is mainly used to treat symptoms such as fullness and distension in the chest and abdomen, nausea, and vomiting. It has the effects of drying dampness and resolving phlegm, regulating qi and relieving fullness. Modern research shows that it has the effects of promoting digestive juice secretion, anti-ulcer, liver protection, antibacterial, anti-inflammatory and analgesic, inhibiting platelet aggregation, lowering blood pressure, relaxing vascular smooth muscle, and relaxing muscles. The flower buds are used medicinally, and the medicinal material is called Magnolia officinalis flower, which has the effects of aromatically resolving dampness, regulating qi, and relieving chest congestion. The bark and flowers contain chemical components such as lignans, volatile oils, and alkaloids. The main lignans include honokiol, magnolol, and isomagnolol; the volatile oils include itsoyl alcohol, elemol, and caryophyllene; the main alkaloids include magnocurarine. Honokiol, magnolol, and magnocurarine are the active ingredients with muscle-relaxing effects.

[0062] Ginger-processed Pinellia: It is pungent and warm in nature. Due to its spicy, numbing, and throat-irritating taste, it is used to dry dampness and resolve phlegm, relieve nausea and vomiting, and dissipate lumps and nodules. It is used for cough and asthma with excessive phlegm, dizziness and palpitations due to phlegm retention, vertigo due to internal phlegm, vomiting and nausea, chest and epigastric fullness, and globus hystericus. When used externally, it is used to treat carbuncles and phlegm nodules. Ginger-processed Pinellia is primarily used to relieve nausea and vomiting.

[0063] Coptis chinensis: Clears heat and drains fire; dries dampness; detoxifies. It is mainly used for high fever due to pathogenic heat entering the heart meridian; irritability; delirium or vomiting and nosebleeds due to excessive heat forcing blood to flow erratically; damp-heat chest tightness; diarrhea; dysentery; restlessness and insomnia due to excessive heart fire; vomiting or excessive hunger due to stomach heat; red and swollen eyes due to liver fire; as well as sores caused by heat toxins; boils spreading; swollen and painful gums; sores in the mouth and tongue; otitis media; genital swelling; hemorrhoids; eczema; and burns.

[0064] Dried ginger: It has the effects of warming the middle jiao and dispelling cold, restoring yang and unblocking the meridians, and warming the lungs and resolving phlegm. It is mainly used to treat cold pain in the stomach and abdomen, vomiting and diarrhea, cold limbs and weak pulse, and cough with cold phlegm.

[0065] Modern scientific research has found that its main components are gingerene, phellandrene, camphene, gingerone, gingerol, gingerone, borneol, gingerol, citral, etc. It also contains resin, starch, and various amino acids. It has sedative, analgesic, anti-inflammatory, anticoagulant, anti-hypoxic, and other effects, and has influences on the cardiovascular system, adrenal cortex function, and digestive system.

[0066] Lotus leaf: Clears heat and relieves summer heat, promotes the upward movement of clear yang, cools the blood and stops bleeding. Used for summer heat and thirst, summer dampness diarrhea, spleen deficiency diarrhea, dizziness, hematemesis due to blood heat, hematochezia, and metrorrhagia. Charred lotus leaf astringes, removes blood stasis, and stops bleeding. Used for various bleeding disorders and postpartum hemorrhage. Its chemical components mainly include alkaloids, flavonoids, and volatile oils. It has various pharmacological activities, such as lipid-lowering and weight-loss effects, antioxidant, anti-aging, antibacterial, and anticonvulsant effects, as well as liver-protective and anti-liver fibrosis effects.

[0067] Evening primrose: Sweet and bitter in taste; warm in nature; dispels wind and dampness, strengthens muscles and bones. It is mainly used for wind-cold-dampness arthralgia, and soreness and weakness of muscles and bones.

[0068] Prepared licorice root: sweet in nature and neutral in taste, it harmonizes the middle jiao and relieves spasms, moistens the lungs, detoxifies, and harmonizes other medicines. When prepared, it treats weakness of the spleen and stomach, poor appetite, abdominal pain and loose stools, fatigue and fever, pulmonary tuberculosis and cough, palpitations, and epilepsy; when used raw, it treats sore throat, peptic ulcers, carbuncles and sores, and detoxifies drug poisoning and food poisoning.

[0069] Stir-fried Atractylodes macrocephala with wheat bran: This is a processed form of Atractylodes macrocephala, made by stir-frying raw Atractylodes macrocephala slices with wheat bran. After stir-frying, the drying properties of Atractylodes macrocephala are reduced, and its spleen-strengthening effect is enhanced.

[0070] Fried Bran-Stirred Immature Bitter Orange: Fried bran-stirred immature bitter orange is a traditional Chinese medicine product made by stir-frying immature bitter orange with wheat bran. Traditional medicine believes it is bitter, pungent, and sour in taste, slightly cold in nature, and enters the spleen and stomach meridians. It has the effects of breaking up qi stagnation, resolving phlegm, and dispersing masses. After being stir-fried with wheat bran, the medicinal properties of immature bitter orange become milder, reducing its harshness, and it is better at resolving stagnation and dispersing masses. It is often used to treat food stagnation causing epigastric fullness, constipation due to food stagnation, and damp-heat diarrhea.

[0071] In summary, this invention provides a traditional Chinese medicine composition for invigorating the spleen and resolving turbidity, and its preparation method. This composition has the functions of invigorating the spleen, replenishing qi, promoting the upward movement of clear qi, regulating qi, harmonizing the stomach, and reducing turbidity. In this formula, ginseng, poria, atractylodes macrocephala, and prepared licorice root invigorate qi and strengthen the spleen; lotus leaf invigorates the spleen and raises yang; immature bitter orange and magnolia bark regulate qi, eliminate fullness and dissipate stagnation; coptis chinensis, bitter and cold, clears heat, dries dampness, and eliminates fullness; pinellia ternata, pungent and warm, disperses stagnation and harmonizes the stomach; and a small amount of dried ginger, pungent and hot, warms the middle jiao and dispels cold. The three herbs work together, opening up the qi with their pungent properties and descending with their bitter properties, regulating the qi mechanism. Evening primrose, a local specialty of Xinjiang, has the effect of removing dampness and resolving turbidity. The entire formula invigorates the spleen, replenishes qi, promotes the upward movement of clear qi, regulates qi, harmonizes the stomach, and reduces turbidity, thus achieving a balance in the ascending, descending, entering, digesting, and drying of dampness in the spleen and stomach. It is used for MAFLD caused by spleen deficiency and impaired transportation and transformation, resulting in the mutual binding of cold and heat, dysfunction of ascending and descending qi, and internal retention of dampness and turbidity, with significant clinical efficacy.

[0072] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0073] The embodiments described above are merely illustrative of several implementations of the present invention, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the protection scope of the present invention. Therefore, the protection scope of this invention patent should be determined by the appended claims.

Claims

1. A traditional Chinese medicine composition for strengthening the spleen and resolving turbidity, characterized in that, The traditional Chinese medicine composition is made from the following raw materials in parts by weight: Atractylodes macrocephala 20-30 parts, ginseng 10-15 parts, Poria cocos 20-30 parts, Citrus aurantium 10-20 parts, Magnolia officinalis 10-12 parts, Pinellia ternata 9-12 parts, Coptis chinensis 3-10 parts, dried ginger 6-10 parts, Nelumbo nucifera leaf 10-20 parts, evening primrose 10-15 parts, and prepared licorice root 6-10 parts.

2. The traditional Chinese medicine composition as described in claim 1, characterized in that, The Atractylodes macrocephala mentioned is stir-fried with wheat bran, and the Citrus aurantium mentioned is stir-fried with wheat bran.

3. The traditional Chinese medicine composition according to claim 1, characterized in that, The traditional Chinese medicine composition is preferably made from the following raw materials in parts by weight: 25 parts of Atractylodes macrocephala, 13 parts of ginseng, 25 parts of Poria cocos, 15 parts of Citrus aurantium, 11 parts of Magnolia officinalis, 11 parts of Pinellia ternata, 7 parts of Coptis chinensis, 8 parts of dried ginger, 5 parts of lotus leaf, 13 parts of evening primrose, and 8 parts of prepared licorice root.

4. The method for preparing the traditional Chinese medicine composition according to any one of claims 1-3, characterized in that, The preparation method includes the following steps: weighing each raw material, pretreatment, extraction, and concentration. Weigh each raw material: Weigh the following ingredients in the composition: Atractylodes macrocephala, ginseng, Poria cocos, Citrus aurantium, Magnolia officinalis, Pinellia ternata, Coptis chinensis, dried ginger, Nelumbo nucifera leaf, evening primrose, and prepared licorice root. Pre-processing: Atractylodes macrocephala and Citrus aurantium are stir-fried with wheat bran, while the remaining medicinal materials are cleaned and cut. Extraction: Add 8-10 times the amount of water to the processed medicinal materials, decoct 1-3 times, 0.5-0.75 hours each time, and combine the decoctions; Concentration: Simmer the decoction over low heat until it becomes a thick paste.

5. The use of the traditional Chinese medicine composition according to any one of claims 1-3 or the traditional Chinese medicine composition prepared by the preparation method according to claim 4 in the preparation of a medicine for strengthening the spleen and eliminating turbidity.

6. The traditional Chinese medicine composition according to any one of claims 1-3 or the use as described in claim 4, characterized in that, The medicine has the effect of strengthening the spleen and clearing away turbidity.

7. The use as described in claim 5, characterized in that, The traditional Chinese medicine composition is in solid, semi-solid, or liquid form.

8. The use as described in claim 7, characterized in that, The traditional Chinese medicine composition is a decoction, granules, ointment, tablets, capsules, oral liquid, powder, or prepared slices; preferably, the medicine is a decoction or granules.