Modular, on-line replaceable extracorporeal membrane oxygenator

Abstract

The present application relates to the technical field of medical devices, and provides a modular and online replaceable extracorporeal membrane oxygenator, comprising a plurality of membrane lung modules, an inlet pipe, first self-sealing joints, an outlet pipe and second self-sealing joints. The inlet pipe, the first self-sealing joints and the membrane lung modules are arranged one by one in correspondence, and the inlet pipe is detachably connected through the corresponding first self-sealing joint and the inlet of the corresponding membrane lung module; the outlet pipe, the second self-sealing joints and the membrane lung modules are arranged one by one in correspondence, and the outlet pipe is detachably connected through the corresponding second self-sealing joint and the outlet of the corresponding membrane lung module. The modular and online replaceable extracorporeal membrane oxygenator of the present application, by arranging a plurality of blood treatment paths in parallel, enables the remaining membrane lung modules to continue treating blood and supplying the patient in the case that part of the membrane lung modules cannot normally operate, so as to minimize the impact on the patient's physical condition during replacement of the membrane lung modules.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a modular, online replaceable extracorporeal membrane oxygenation (ECMO) device. Background Technology

[0002] Extracorporeal membrane oxygenation (ECMO) is mainly used to provide continuous extracorporeal respiration and circulation for patients with severe cardiopulmonary failure in order to maintain their lives. It mainly consists of equipment and devices such as centrifugal pumps, oxygenators (membrane lungs), and tubing.

[0003] When working at a patient's bedside, the patient's hypoxic venous blood is drawn out under negative pressure by a centrifugal pump, oxygenated by an oxygenator (membrane lung), and then returned to the patient as hyperxic arterial blood. The oxygenator (membrane lung) and its tubing are in prolonged contact with blood, making them prone to malfunctions or adverse events. For example, thrombosis can occur inside the oxygenator, increasing the transmembrane pressure gradient and reducing oxygenation efficiency. This severely limits the continuous use of the oxygenator (membrane lung), often requiring replacement of the entire oxygenator (membrane lung), centrifugal pump, and tubing. This replacement process is lengthy and can easily lead to adverse consequences such as anemia in the patient. Summary of the Invention

[0004] This invention provides an online replaceable extracorporeal membrane oxygenator (ECMO) to solve the problem that the replacement time of existing oxygenators (membrane lungs) is long and that the replacement period can easily affect the patient's health.

[0005] This invention provides a modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device, comprising: Multiple membrane lung modules; An inlet tube and a first self-sealing connector are provided, with the inlet tube, the first self-sealing connector and the membrane lung module being provided in a one-to-one correspondence. The inlet tube is detachably connected to the inlet of the corresponding membrane lung module through the corresponding first self-sealing connector. The inlet tube is used to introduce blood into the membrane lung module, and the first self-sealing connector is used to seal the inlet tube when the inlet tube and the membrane lung module are separated. An outlet pipe and a second self-sealing connector are provided, with the outlet pipe, the second self-sealing connector and the membrane lung module being provided in a one-to-one correspondence. The outlet pipe is detachably connected to the outlet of the corresponding membrane lung module through the corresponding second self-sealing connector. The outlet pipe is used to introduce blood processed by the membrane lung module into the blood vessels, and the second self-sealing connector is used to seal the outlet pipe when the outlet pipe and the membrane lung module are separated.

[0006] The modular, online-replaceable extracorporeal membrane oxygenator according to the present invention further includes: The first main tube has an inlet end for connecting to a blood vessel, and an outlet end for connecting to each of the inlet tubes respectively. The second main pipe has an outlet end for connection to a blood vessel, and an inlet end for connection to each of the outlet pipes.

[0007] The modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device according to the present invention includes, respectively, the first self-sealing connector and the second self-sealing connector comprising: A first connector includes: a first housing and a first sealing assembly; a first channel is formed within the first housing, and the first sealing assembly is movably disposed within the first channel; the first housing of the first self-sealing connector is connected to the outlet end of the inlet pipe, and the first housing of the second self-sealing connector is connected to the inlet end of the outlet pipe. The second connector has a second channel formed therein that communicates with the membrane lung module; When the first connector and the second connector are plugged into each other, the first sealing assembly opens the first channel to make the first channel and the second channel communicate; when the first connector and the second connector are separated, the first sealing assembly closes the first channel.

[0008] According to the modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device of the present invention, the first sealing assembly comprises: A first valve core is disposed within the first channel, and the first valve core has a first opening; A first sealing structure is movably disposed within the first channel; when the first connector and the second connector are separated, the first sealing structure seals the first opening to cooperate with the first valve core to close the first channel; when the first connector and the second connector are plugged into each other, a portion of the structure of the second connector abuts against the first sealing structure to allow the first sealing structure to open the first opening.

[0009] According to the modular, online replaceable extracorporeal membrane oxygenator of the present invention, the first valve core is columnar, and the first opening is provided on the peripheral wall of the first valve core; The first sealing structure includes a first sealing ring and a first elastic member. The first sealing ring is movably sleeved on the first valve core. One end of the first elastic member is connected to at least one of the first housing or the first valve core, and the other end is connected to the end of the first sealing ring away from the second connector.

[0010] According to the modular, online replaceable extracorporeal membrane oxygenator of the present invention, the second connector includes: a second housing and a second sealing assembly; a second channel is formed within the second housing, and the second sealing assembly is movably disposed within the second channel; When the first connector and the second connector are plugged into each other, the second sealing assembly opens the second channel to make the first channel and the second channel communicate; when the first connector and the second connector are separated, the second sealing assembly closes the second channel.

[0011] According to the modular, online-replaceable extracorporeal membrane oxygenator of the present invention, the second sealing assembly includes: The second valve core is disposed in the second channel and has a second opening; The second sealing structure is movably disposed within the second channel; when the first connector and the second connector are separated, the second sealing structure seals the second opening to cooperate with the second valve core to close the second channel; when the first connector and the second connector are inserted into each other, the first sealing structure abuts against the second sealing structure to allow the second sealing structure to open the second opening.

[0012] According to the modular, online replaceable extracorporeal membrane oxygenator of the present invention, the second valve core is columnar, and the second opening is provided on the peripheral wall of the second valve core; The second sealing structure includes: a second sealing ring and a second elastic member. The second sealing ring is movably sleeved on the second valve core. One end of the second elastic member is connected to at least one of the second housing or the second valve core, and the other end is connected to the end of the second sealing ring away from the first plug.

[0013] The modular, online-replaceable extracorporeal membrane oxygenator according to the present invention further includes: A locking mechanism is disposed between the corresponding first and second connectors; the locking mechanism is capable of switching between a locked state and an unlocked state. When the locking mechanism is in the locked state, the locking mechanism locks the first connector and the second connector; when the locking mechanism is in the unlocked state, the first connector and the second connector can be separated from each other.

[0014] The modular, online-replaceable extracorporeal membrane oxygenator according to the present invention further includes: an operating component; wherein the operating component and the membrane oxygenator module are configured in a one-to-one correspondence. The operating components are respectively connected to the locking mechanisms corresponding to the membrane lung modules, and are used to drive the locking mechanisms to switch between the locked state and the unlocked state.

[0015] The modular, online-replaceable extracorporeal membrane oxygenator (ECMO) of the present invention, by setting multiple sets of inlet tubes, membrane lung modules, and outlet tubes, can sequentially connect in parallel to form independent blood processing paths. This allows for the oxygenation of the patient's blood before reinfusion into the patient's blood vessels. The parallel arrangement of multiple blood processing paths ensures that even if some membrane lung modules fail to operate normally, the remaining modules can continue to process blood and supply it to the patient, minimizing the impact on the patient's health during membrane lung module replacement. Furthermore, by setting a first self-sealing connector and a second self-sealing connector between the membrane lung module and the corresponding tubing, a detachable connection between the membrane lung module and the corresponding tubing is achieved, facilitating the disassembly and replacement of individual membrane lung modules. Simultaneously, the first and second self-sealing connectors can seal the tubing after the membrane lung module and tubing are separated, reducing blood loss from the patient. This effectively solves the problems of long replacement times and potential health impacts on patients during replacement in existing oxygenators (membrane lungs). Attached Figure Description

[0016] To more clearly illustrate the technical solutions in this invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of a modular, online replaceable extracorporeal membrane oxygenation (ECMO) device provided in an embodiment of the present invention.

[0018] Figure 2 This is a schematic diagram of the inlet pipe, outlet pipe, first main pipe, and second main pipe provided in an embodiment of the present invention.

[0019] Figure 3 This is a schematic diagram of the first self-sealing joint, the second self-sealing joint, the locking mechanism, and the operating element provided in the embodiments of the present invention.

[0020] Figure 4 This is a cross-sectional view of the first and second connectors provided in the embodiment of the present invention in a mutually plugged state.

[0021] Figure 5 This is a cross-sectional view of the first and second connectors provided in the embodiments of the present invention in a state of mutual separation.

[0022] Figure 6This is a schematic diagram of a modular, online replaceable extracorporeal membrane oxygenator provided in an embodiment of the present invention, in the case of disassembling the first module.

[0023] Figure 7 This is a schematic diagram of a modular, online replaceable extracorporeal membrane oxygenator provided in an embodiment of the present invention, in the case of installing the first module.

[0024] Figure label: 1. Modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device; 11. Membrane lung module; 111. First module; 112. Second module; 12. Inlet tube; 13. First self-sealing joint; 131. First connector; 1311. First housing; 1312. First sealing assembly; 1313. First valve core; 1314. First sealing structure; 1315. First sealing ring; 13151. First ring body; 13152. Second ring body; 13153. First limiting protrusion; 1316. First elastic element; 132. Second connector; 1321. Second housing; 1322. Second sealing assembly; 1323. Second valve core; 1324. Second sealing structure; 1325. Second sealing ring; 13251. Third ring body; 13252. Fourth ring body; 13253. Second limiting protrusion; 1326. Second elastic element; 14. Outlet pipe; 15. Second self-sealing joint; 16. First main pipe; 17. Second main pipe; 18. Locking mechanism; 19. Operating component. Detailed Implementation

[0025] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this invention. All other embodiments obtained by those skilled in the art based on the embodiments of this invention without creative effort are within the scope of protection of this invention.

[0026] The following is combined Figures 1-5 The present invention describes a modular, online-replaceable extracorporeal membrane oxygenator.

[0027] like Figure 1 , Figure 2 and Figure 3 As shown, the present invention provides a modular, online replaceable extracorporeal membrane oxygenator 1, comprising: multiple membrane oxygenation modules 11, an inlet tube 12, a first self-sealing connector 13, an outlet tube 14, and a second self-sealing connector 15.

[0028] The inlet tube 12, the first self-sealing connector 13, and the membrane lung module 11 are arranged in a one-to-one correspondence. The inlet tube 12 is detachably connected to the inlet of the corresponding membrane lung module 11 through the corresponding first self-sealing connector 13. The inlet tube 12 is used to introduce blood into the membrane lung module 11, and the first self-sealing connector 13 is used to seal the inlet tube 12 when the inlet tube 12 and the membrane lung module 11 are separated. The outlet tube 14, the second self-sealing connector 15, and the membrane lung module 11 are arranged in a one-to-one correspondence. The outlet tube 14 is detachably connected to the outlet of the corresponding membrane lung module 11 through the corresponding second self-sealing connector 15. The outlet tube 14 is used to pass the blood processed by the membrane lung module 11 into the blood vessels. The second self-sealing connector 15 is used to seal the outlet tube 14 when the outlet tube 14 and the membrane lung module 11 are separated.

[0029] In this embodiment, the membrane lung module 11 can be used to oxygenate blood. Each membrane lung module 11 in this embodiment is equipped with a corresponding inlet pipe 12, a first self-sealing connector 13, an outlet pipe 14, and a second self-sealing connector 15. The inlet pipe 12, the membrane lung module 11, and the outlet pipe 14 are connected in sequence to form a processing path for the patient's blood.

[0030] Specifically, the patient's blood vessels (usually veins) are connected to the inlet tube 12 so that the patient's blood can be introduced into the membrane lung module 11 through the inlet tube 12 by a matching pump set. After the membrane lung module 11 oxygenates the blood, it is returned to the patient's blood vessels through the outlet tube 14.

[0031] Meanwhile, this embodiment sets up multiple membrane lung modules 11, each of which, together with its matching inlet tube 12 and outlet tube 14, can form an independent blood processing path. These multiple blood processing paths are connected in parallel, enabling simultaneous processing of the patient's blood. This design ensures that even if some membrane lung modules 11 malfunction and cannot operate normally, the remaining normal membrane lung modules 11 can continue to process blood and supply it to the patient, thereby reducing the impact of insufficient blood supply on the patient's physical condition in a short period of time and minimizing the impact on the patient's physical condition due to the replacement of membrane lung modules 11.

[0032] In addition, this embodiment provides a first self-sealing connector 13 between the membrane lung module 11 and the inlet tube 12, and a second self-sealing connector 15 between the membrane lung module 11 and the outlet tube 14. The first self-sealing connector 13 and the second self-sealing connector 15 can achieve detachable connection between the membrane lung module 11 and the corresponding tubing through quick plug-in or other methods, so that the membrane lung module 11 can be easily connected and disconnected from the outlet tube 14 and the inlet tube 12, so as to disassemble and replace a single membrane lung module 11. At the same time, the first self-sealing connector 13 and the second self-sealing connector 15 can seal the tubing after the membrane lung module 11 is separated from the inlet tube 12 and the outlet tube 14 through their own sealing structure, preventing the patient's blood from leaking from the inlet tube 12 or the outlet tube 14, making it more convenient to use.

[0033] The modular, online-replaceable extracorporeal membrane oxygenator 1 of the present invention, by setting multiple sets of inlet tubes 12, membrane lung modules 11, and outlet tubes 14, can sequentially connect the inlet tubes 12, membrane lung modules 11, and outlet tubes 14 in parallel to form independent blood processing pathways. This allows for the oxygenation of the patient's blood before reinfusion into the patient's blood vessels. The parallel arrangement of multiple blood processing pathways ensures that even if some membrane lung modules 11 fail to operate normally, the remaining membrane lung modules 11 can continue to process blood and supply it to the patient, minimizing the impact on the patient's physical condition during membrane lung module replacement. Furthermore, by setting a first self-sealing connector 13 and a second self-sealing connector 15 between the membrane lung module 11 and the corresponding tubing, a detachable connection between the membrane lung module 11 and the corresponding tubing can be achieved, facilitating the disassembly and replacement of a single membrane lung module 11. At the same time, the first self-sealing connector 13 and the second self-sealing connector 15 can also seal the tubing after the membrane lung module 11 and the tubing are separated, reducing blood loss from the patient. This effectively solves the problem of long replacement time of oxygenators (membrane lungs) in the prior art, which can easily affect the patient's health during the replacement period.

[0034] In some embodiments, such as Figure 1 and Figure 2 As shown, the modular, online replaceable extracorporeal membrane oxygenator 1 also includes: a first main pipe 16 and a second main pipe 17; the inlet end of the first main pipe 16 is used to connect to a blood vessel, and the outlet end of the first main pipe 16 is connected to each inlet tube 12 respectively; the outlet end of the second main pipe 17 is used to connect to a blood vessel, and the inlet end of the second main pipe 17 is connected to each outlet tube 14 respectively.

[0035] In this embodiment, by connecting the inlet of each inlet tube 12 to the first main tube 16, the first main tube 16 can be implanted into the patient's blood vessels so that the blood to be processed can be diverted to each inlet tube 12 through the first main tube 16, and then passed into the corresponding membrane lung module 11 for processing through the inlet tube 12; the blood processed by the membrane lung module 11 can flow into the second main tube 17 through the corresponding outlet tube 14. The second main tube 17 can be implanted into the patient's blood vessels so that the processed blood can be returned to the patient. The first main tube 16 and the second main tube 17 in this embodiment are mainly used to connect with the patient's blood vessels, which is convenient and practical.

[0036] In some embodiments, such as Figure 3 , Figure 4 and Figure 5 As shown, both the first self-sealing connector 13 and the second self-sealing connector 15 include: a first plug connector 131 and a second plug connector 132.

[0037] The first connector 131 includes: a first housing 1311 and a first sealing component 1312; a first channel is formed in the first housing 1311, and the first sealing component 1312 is movably disposed in the first channel; the first housing 1311 of the first self-sealing connector 13 is connected to the outlet end of the inlet pipe 12, and the first housing 1311 of the second self-sealing connector 15 is connected to the inlet end of the outlet pipe 14.

[0038] The second connector 132 has a second channel that communicates with the membrane lung module 11.

[0039] When the first connector 131 and the second connector 132 are plugged into each other, the first sealing assembly 1312 opens the first channel to make the first channel and the second channel communicate; when the first connector 131 and the second connector 132 are separated from each other, the first sealing assembly 1312 closes the first channel.

[0040] In this embodiment, by providing a first channel in the first connector 131 and a second channel in the second connector 132, when the first connector 131 and the second connector 132 are connected to each other, the inlet pipe 12 or outlet pipe 14, the first channel, the second channel, and the membrane lung module 11 can be connected in sequence to allow blood to flow into the membrane lung module 11 or from the membrane lung module 11 to the blood vessels. At the same time, by providing a first sealing component 1312 in the first channel, the first sealing component 1312 can adjust its position or state according to the connection state of the first connector 131 and the second connector 132, so that when the first connector 131 and the second connector 132 are connected to each other, the first channel can be opened to allow blood to flow between the first channel and the second channel, and the first channel can be closed when the first connector 131 and the second connector 132 are separated to prevent blood from flowing out of the inlet pipe 12 or the outlet pipe 14.

[0041] Specifically, in some embodiments, such as Figure 4 and Figure 5 As shown, the first sealing assembly 1312 includes: a first valve core 1313 and a first sealing structure 1314.

[0042] The first valve core 1313 is disposed in the first channel, and the first valve core 1313 is provided with a first opening.

[0043] The first sealing structure 1314 is movably disposed within the first channel; when the first connector 131 and the second connector 132 are separated from each other, the first sealing structure 1314 seals the first opening to cooperate with the first valve core 1313 to close the first channel; when the first connector 131 and the second connector 132 are inserted into each other, a portion of the structure of the second connector 132 abuts against the first sealing structure 1314 to open the first opening.

[0044] In this embodiment, by setting a first valve core 1313 in the first channel, it can be understood that the first valve core 1313 can be set at either the end or the middle of the first channel. The first valve core 1313 has a first opening, so that the two channels of the first valve core 1313 can only be connected through the first opening. At the same time, by configuring a movable first sealing structure 1314 in the first channel, when the first connector 131 and the second connector 132 are separated, the initial position of the first sealing structure 1314 is located at the first opening, blocking the first opening, thereby preventing the channels on both sides of the first valve core 1313 from being connected, thus achieving the sealing of the pipeline.

[0045] When the first connector 131 and the second connector 132 are plugged into each other, a portion of the structure of the second connector 132 can extend into the first channel and abut against the first sealing structure 1314, thereby affecting the position of the first sealing structure 1314 and allowing the first sealing structure 1314 to move away from the first opening to open the first opening, thereby connecting the channels on both sides of the first valve core 1313 so that blood can pass through the first channel.

[0046] After the first connector 131 and the second connector 132 are separated again, the first sealing structure 1314 and the second connector 132 are no longer in contact and can re-close the first opening by resetting part of their own structure.

[0047] Specifically, in some embodiments, such as Figure 4 and Figure 5 As shown, the first valve core 1313 is columnar, and the first opening is located on the peripheral wall of the first valve core 1313.

[0048] The first sealing structure 1314 includes a first sealing ring 1315 and a first elastic member 1316. The first sealing ring 1315 is movably sleeved on the first valve core 1313. One end of the first elastic member 1316 is connected to at least one of the first housing 1311 or the first valve core 1313, and the other end is connected to the end of the first sealing ring 1315 that is away from the second connector 132.

[0049] It is understood that the first housing 1311 is usually tubular. In this embodiment, by designing the first valve core 1313 as a column, it can better fit the shape of the first channel. In practical applications, the axial direction of the first valve core 1313 can be extended along the extension direction of the first channel. The first valve core 1313 is provided with a first opening so as to cooperate with the first sealing ring 1315 sleeved on the first valve core 1313 to open or close the first channel. The first sealing ring 1315 can move axially relative to the first valve core 1313 so as to block or leave the first opening.

[0050] Meanwhile, by providing a first elastic element 1316 between at least one of the first sealing ring 1315 and the first housing 1311 or the first valve core 1313, the first elastic element 1316 can adjust the position of the first sealing ring 1315 by cooperating with the second plug 132 through its own elastic deformation.

[0051] Specifically, when the first connector 131 and the second connector 132 are separated, the first elastic element 1316 naturally extends, keeping the first sealing ring 1315 in the position of the first opening and sealing the first opening, thereby preventing the channels on both sides of the first valve core 1313 from connecting and achieving the sealing of the pipeline.

[0052] When the first connector 131 and the second connector 132 are plugged into each other, part of the structure of the second connector 132 can extend into the first channel and abut against the first sealing ring 1315, pushing the first sealing ring 1315 to move towards the side of the first elastic member 1316, compressing the first elastic member 1316 while moving away from the first opening, so as to open the first opening, thereby connecting the channels on both sides of the first valve core 1313, so that blood vessels can pass through the first channel.

[0053] After the first connector 131 and the second connector 132 are separated again, the first elastic element 1316 can rebound to reset the first sealing ring 1315, thereby re-sealing the first opening.

[0054] In some specific embodiments, such as Figure 4 and Figure 5As shown, the first valve core 1313 is cylindrical, and the outer peripheral wall of the first valve core 1313 is provided with an outwardly extending outer edge structure, which is used to connect or abut with the channel wall of the first channel; the outer peripheral wall of the first valve core 1313, the outer edge structure and the channel wall of the first channel together form an accommodating space for accommodating the first sealing ring 1315 and the first elastic member 1316.

[0055] The first sealing ring 1315 includes a first ring body 13151 and a second ring body 13152 connected sequentially along the axial direction. The inner ring of the first ring body 13151 fits against the outer peripheral wall of the first valve core 1313, so that the first opening is completely sealed when a portion of the first ring body 13151 is opposite to the first opening. The inner diameter of the second ring body 13152 is larger than the outer diameter of the first valve core 1313, so that a certain gap is left between the second ring body 13152 and the outer peripheral wall of the first valve core 1313, allowing blood to flow out from the first opening and along the gap between the second ring body 13152 and the outer peripheral wall of the first valve core 1313 when a portion of the second ring body 13152 is opposite to the first opening. Simultaneously, the outer peripheral wall of the second ring body 13152 fits against the channel wall of the first channel to enhance sealing. A first elastic element 1316 is disposed between the outer edge structure of the first valve core 1313 and the first ring body 13151.

[0056] When the first connector 131 and the second connector 132 separate, the first elastic element 1316 naturally extends, keeping the first ring 13151 in the position of the first opening and sealing the first opening.

[0057] When the first connector 131 and the second connector 132 are plugged into each other, part of the structure of the second connector 132 can extend into the first channel and abut against the second ring body 13152, pushing the first sealing ring 1315 to move to one side of the first elastic member 1316, so that the first ring body 13151 leaves the first opening and the second ring body 13152 moves to the position of the first opening, and blood can flow between the first channel and the second channel along the gap between the first opening, the second ring body 13152 and the outer peripheral wall of the first valve core 1313.

[0058] After the first connector 131 and the second connector 132 are separated again, the first elastic element 1316 can rebound to reset the first ring 13151, thereby re-closing the first opening.

[0059] Furthermore, in some embodiments, such as Figure 4 and Figure 5As shown, a first limiting protrusion 13153 is provided on the inner side of the first ring body 13151. The first limiting protrusion 13153 extends into the first opening so as to cooperate with the inner wall of the first opening to limit the first sealing ring 1315 and prevent the first sealing ring 1315 from falling off from the first valve core 1313 and the first channel.

[0060] In some embodiments, such as Figure 4 and Figure 5 As shown, the second connector 132 includes: a second housing 1321 and a second sealing assembly 1322; a second channel is formed in the second housing 1321, and the second sealing assembly 1322 is movably disposed in the second channel.

[0061] When the first connector 131 and the second connector 132 are plugged into each other, the second sealing assembly 1322 opens the second channel to connect the first channel and the second channel; when the first connector 131 and the second connector 132 are separated from each other, the second sealing assembly 1322 closes the second channel.

[0062] In this embodiment, a second sealing component 1322 is provided in the second channel of the second housing 1321. The second sealing component 1322 can adjust its position or state according to the insertion state of the first connector 131 and the second connector 132, so that the second channel can be opened when the first connector 131 and the second connector 132 are inserted into each other, so that blood can flow between the second channel and the second channel, and the second channel can be closed when the first connector 131 and the second connector 132 are separated from each other, so as to prevent blood in the membrane lung module 11 from leaking out of the outlet or inlet; it is understood that the blood in the membrane lung module 11 can be recycled and reused later.

[0063] In some embodiments, such as Figure 4 and Figure 5 As shown, the second sealing assembly 1322 includes: a second valve core 1323 and a second sealing structure 1324; the second valve core 1323 is disposed in the second channel and has a second opening connecting both sides.

[0064] The second sealing structure 1324 is movably disposed within the second channel; when the first connector 131 and the second connector 132 are separated from each other, the second sealing structure 1324 seals the second opening to cooperate with the second valve core 1323 to close the first channel; when the first connector 131 and the second connector 132 are inserted into each other, the first sealing structure 1314 abuts against the second sealing structure 1324 to open the second opening.

[0065] In this embodiment, by setting a second valve core 1323 in the second channel, it can be understood that the second valve core 1323 can be set at either the end or the middle of the second channel. The second valve core 1323 has a second opening, so that the two channels of the second valve core 1323 can only be connected through the second opening. At the same time, by configuring a movable second sealing structure 1324 in the second channel, when the first connector 131 and the second connector 132 are separated, the initial position of the second sealing structure 1324 is located at the second opening, blocking the second opening, thereby preventing the channels on both sides of the second valve core 1323 from being connected, thus achieving the sealing of the pipeline.

[0066] When the first connector 131 and the second connector 132 are inserted into each other, the first sealing structure 1314 of the second connector 132 can extend into the second channel and abut against the second sealing structure 1324, affecting the position of the second sealing structure 1324. This allows the second sealing structure 1324 to move away from the second opening, thereby opening the second opening and connecting the channels on both sides of the second valve core 1323, allowing blood to pass through the second channel. Simultaneously, it is understood that because the first sealing structure 1314 and the second sealing structure 1324 abut against each other, they can cooperate to seal the joint between them, preventing blood from leaking from the joint between the first sealing structure 1314 and the second sealing structure 1324, as well as between the first connector 131 and the second connector 132.

[0067] In some embodiments, such as Figure 4 and Figure 5 As shown, the second valve core 1323 is columnar, and the second opening is located on the peripheral wall of the second valve core 1323.

[0068] The second sealing structure 1324 includes: a second sealing ring 1325 and a second elastic member 1326. The second sealing ring 1325 is movably sleeved on the second valve core 1323. One end of the second elastic member 1326 is connected to at least one of the second housing 1321 or the second valve core 1323, and the other end is connected to the end of the second sealing ring 1325 that is away from the first plug 131.

[0069] It is understood that the second housing 1321 is usually tubular. In this embodiment, by designing the second valve core 1323 as a column, it can better adapt to the shape of the second channel. In practical applications, the axial direction of the second valve core 1323 can be extended along the extension direction of the second channel. The second valve core 1323 is provided with a second opening so as to cooperate with the second sealing ring 1325 sleeved on the second valve core 1323 to open or close the second channel. The second sealing ring 1325 can move axially relative to the second valve core 1323 so as to block or leave the second opening.

[0070] Meanwhile, by providing a second elastic element 1326 between at least one of the second sealing ring 1325 and the second housing 1321 or the second valve core 1323, the second elastic element 1326 can adjust the position of the second sealing ring 1325 through its own elastic deformation in conjunction with the second plug 132.

[0071] Specifically, when the first connector 131 and the second connector 132 are separated, the second elastic element 1326 naturally extends, keeping the second sealing ring 1325 in the position of the second opening and sealing the second opening, thereby preventing the channels on both sides of the second valve core 1323 from connecting and achieving the sealing of the pipeline.

[0072] When the first connector 131 and the second connector 132 are plugged into each other, the first sealing structure 1314 of the first connector 131 abuts against the second sealing ring 1325, pushing the second sealing ring 1325 to move towards the side of the second elastic member 1326, compressing the second elastic member 1326 while moving away from the second opening, so as to open the second opening, thereby connecting the channels on both sides of the second valve core 1323, so that the blood vessel can pass through the second channel.

[0073] After the first connector 131 and the second connector 132 are separated again, the second elastic element 1326 can rebound to reset the second sealing ring 1325, thereby re-closing the second opening.

[0074] In some specific embodiments, such as Figure 4 and Figure 5 As shown, the second valve core 1323 is cylindrical, and the outer peripheral wall of the second valve core 1323 is provided with an outwardly extending outer edge structure, which is used to connect or abut against the channel wall of the second channel; the outer peripheral wall of the second valve core 1323, the outer edge structure and the channel wall of the second channel together form an accommodating space for accommodating the second sealing ring 1325 and the second elastic member 1326.

[0075] The second sealing ring 1325 includes a third ring body 13251 and a fourth ring body 13252 connected sequentially along the axial direction. The inner ring of the third ring body 13251 fits against the outer peripheral wall of the second valve core 1323, so that when a portion of the structure of the third ring body 13251 is opposite to the second opening, it can completely seal the second opening. The inner diameter of the fourth ring body 13252 is larger than the outer diameter of the second valve core 1323, so that a certain gap is left between the outer peripheral walls of the fourth ring body 13252 and the second valve core 1323, allowing blood to flow out from the second opening and along the gap between the outer peripheral walls of the fourth ring body 13252 and the second valve core 1323 when a portion of the structure of the fourth ring body 13252 is opposite to the second opening. Simultaneously, the outer peripheral wall of the fourth ring body 13252 fits against the channel wall of the second channel to enhance sealing. A second elastic element 1326 is disposed between the outer edge structure of the second valve core 1323 and the third ring body 13251.

[0076] When the first connector 131 and the second connector 132 separate, the second elastic element 1326 naturally extends, keeping the third ring 13251 in the position of the second opening and sealing the second opening.

[0077] When the first connector 131 and the second connector 132 are inserted into each other, the second ring 13152 of the first connector 131 can extend into the second channel and abut against the fourth ring 13252, pushing the second sealing ring 1325 towards the side of the second elastic member 1326. This causes the third ring 13251 to leave the second opening, and the fourth ring 13252 to move to the position of the second opening. Blood can then flow between the second channel and the second channel along the gap between the second opening and the outer peripheral wall of the fourth ring 13252 and the second valve core 1323. Simultaneously, the second ring 13152 and the fourth ring 13252 are mated together, and under the action of the first elastic member 1316 and the second elastic member 1326, a completely sealed channel is formed between the first opening and the second opening to prevent blood from leaking out from the joint between the first connector 131 and the second connector 132.

[0078] After the first connector 131 and the second connector 132 are separated again, the second elastic element 1326 can rebound to reset the third coil 13251, thereby re-closing the second opening.

[0079] Furthermore, in some embodiments, such as Figure 4 and Figure 5 As shown, a second limiting protrusion 13253 is provided on the inner side of the third ring body 13251. The second limiting protrusion 13253 extends into the second opening so as to cooperate with the inner wall of the second opening to limit the second sealing ring 1325 and prevent the second sealing ring 1325 from falling off the second valve core 1323 and the second channel.

[0080] In some embodiments, such as Figure 1 and Figure 3 As shown, the modular, online replaceable extracorporeal membrane oxygenator 1 further includes: a locking mechanism 18, which is disposed between the corresponding first connector 131 and second connector 132; the locking mechanism 18 can switch between a locked state and an unlocked state; when the locking mechanism 18 is in the locked state, the locking mechanism 18 locks the first connector 131 and the second connector 132; when the locking mechanism 18 is in the unlocked state, the first connector 131 and the second connector 132 can be separated from each other.

[0081] In this embodiment, by providing a locking mechanism 18 between the corresponding first connector 131 and second connector 132, the locking mechanism 18 can lock the first connector 131 and second connector 132 when they are plugged into each other, so that the connection between the first connector 131 and second connector 132 is more secure and reliable, and prevents the first connector 131 and second connector 132 from being accidentally separated by external force; and when the membrane lung module 11 needs to be replaced, the locking mechanism 18 can be switched to the unlocked state so that the first connector 131 and second connector 132 can be locked together.

[0082] Alternatively, the locking mechanism 18 may be a snap-on or pin-type structure.

[0083] In one specific embodiment, such as Figure 3 , Figure 4 and Figure 5 As shown, of the first connector 131 and the second connector 132, one is a male connector and the other is a female connector; part of the structure of the male connector can extend into the female connector to achieve the insertion and mating of the two.

[0084] The locking mechanism 18 is annular and movably disposed in a receiving groove on the peripheral wall of the female connector. The locking mechanism 18 can move between a first position and a second position within the receiving groove. When the locking mechanism 18 is in the first position, a portion of the male connector can extend to the female connector and pass through the annular locking mechanism 18. The outer wall of the male connector is provided with a slot adapted to the locking mechanism 18. When the male connector is inserted into the female connector and reaches a predetermined position, the slot corresponds to the position of the locking mechanism 18. At this time, the locking mechanism 18 can be moved to the second position so that a portion of the locking mechanism 18 can move into the slot, thereby locking the two connectors. When it is necessary to separate the two connectors, the locking mechanism 18 can be moved to the first position so that the male connector can be separated from the female connector.

[0085] In some embodiments, such as Figure 1As shown, the modular, online replaceable extracorporeal membrane oxygenator 1 also includes: an operating component 19; the operating component 19 and the membrane oxygenator module 11 are configured in a one-to-one correspondence; the operating component 19 is connected to each locking mechanism 18 corresponding to the corresponding membrane oxygenator module 11, and is used to drive the locking mechanism 18 to switch between the locked state and the unlocked state.

[0086] In this embodiment, the operating member 19 is connected to the locking mechanisms 18 that are matched with the self-sealing joints (first self-sealing joint 13 and second self-sealing joint 15) of the corresponding membrane lung module 11, so that the position of each locking mechanism 18 can be adjusted synchronously by the operating member 19, thereby adjusting the state of the locking mechanism 18 synchronously, so as to disassemble and assemble the corresponding membrane lung module 11.

[0087] In one specific embodiment, such as Figure 1 As shown, the second connectors 132 of the first self-sealing connector 13 and the second connectors 132 of the second self-sealing connector 15 corresponding to the membrane lung module 11 are arranged side by side at the bottom of the membrane lung module 11. Each of the two second connectors 132 is provided with a ring-shaped locking mechanism 18. The operating element 19 is arranged between the two second connectors 132 and is connected to the two locking mechanisms 18 respectively. Medical staff can press the operating element 19 to synchronously drive the locking mechanism 18 to switch to the unlocked state so as to lift the membrane lung module 11 upward and separate the second connectors 132 and the first connector 131 from each other.

[0088] In one specific embodiment, the membrane lung module 11 includes: a first module 111 and a second module 112, the first module 111 being configured with a first self-sealing connector 13 and a second self-sealing connector 15, and the second module 112 being configured with another set of first self-sealing connectors 13 and second self-sealing connectors 15.

[0089] When it is necessary to replace any module (taking the first module 111 as an example), you can first press the corresponding operating piece 19 of the first module 111 to switch the corresponding locking mechanism 18 to the unlocked state, and then lift the first module 111 upwards to separate the two first connectors 131 from the second connectors 132 respectively (e.g., Figure 6 As shown), after the first connector 131 and the second connector 132 are separated, the first connector 131 and the second connector 132 achieve self-sealing through the action of the internal first sealing component 1312 and the second sealing component 1322, respectively.

[0090] When installing the new first module 111, the corresponding locking mechanism 18 can be kept in the locked state. Then, the two second connectors 132 of the first module 111 are aligned with the two first connectors 131 respectively, and the first module 111 is moved so that the second connectors 132 and the corresponding first connectors 131 are plugged in (e.g., ...). Figure 7As shown, the sealing structures inside the first connector 131 and the second connector 132 cooperate to achieve communication. At this time, the locking structure 18 can be switched to the locked state by the operating component 19, thereby completing the replacement of the first module 111. It is understood that if the second module 112 needs to be replaced, the entire operation process is similar to that of replacing the first module 111, and will not be described again here. The entire operation process is convenient and quick, allowing for rapid replacement and significantly reducing blood loss and other impacts on the patient during the replacement process.

[0091] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device, characterized in that, include: Multiple membrane lung modules; An inlet tube and a first self-sealing connector are provided, with the inlet tube, the first self-sealing connector and the membrane lung module being provided in a one-to-one correspondence. The inlet tube is detachably connected to the inlet of the corresponding membrane lung module through the corresponding first self-sealing connector. The inlet tube is used to introduce blood into the membrane lung module, and the first self-sealing connector is used to seal the inlet tube when the inlet tube and the membrane lung module are separated. An outlet pipe and a second self-sealing connector are provided, with the outlet pipe, the second self-sealing connector and the membrane lung module being provided in a one-to-one correspondence. The outlet pipe is detachably connected to the outlet of the corresponding membrane lung module through the corresponding second self-sealing connector. The outlet tube is used to pass blood processed by the membrane lung module into blood vessels, and the second self-sealing connector is used to seal the outlet tube when the outlet tube and the membrane lung module are separated.

2. The modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device according to claim 1, characterized in that, Also includes: The first main tube has an inlet end for connecting to a blood vessel, and an outlet end for connecting to each of the inlet tubes respectively. The second main pipe has an outlet end for connection to a blood vessel, and an inlet end for connection to each of the outlet pipes.

3. The modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device according to claim 1, characterized in that, Both the first self-sealing joint and the second self-sealing joint include: A first connector includes: a first housing and a first sealing assembly; a first channel is formed within the first housing, and the first sealing assembly is movably disposed within the first channel; the first housing of the first self-sealing connector is connected to the outlet end of the inlet pipe, and the first housing of the second self-sealing connector is connected to the inlet end of the outlet pipe. The second connector has a second channel formed therein that communicates with the membrane lung module; When the first connector and the second connector are plugged into each other, the first sealing assembly opens the first channel to make the first channel and the second channel communicate; when the first connector and the second connector are separated, the first sealing assembly closes the first channel.

4. The modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device according to claim 3, characterized in that, The first sealing assembly includes: A first valve core is disposed within the first channel, and the first valve core has a first opening; A first sealing structure is movably disposed within the first channel; when the first connector and the second connector are separated, the first sealing structure seals the first opening to cooperate with the first valve core to close the first channel; when the first connector and the second connector are plugged into each other, a portion of the structure of the second connector abuts against the first sealing structure to allow the first sealing structure to open the first opening.

5. The modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device according to claim 4, characterized in that, The first valve core is cylindrical, and the first opening is located on the peripheral wall of the first valve core; The first sealing structure includes a first sealing ring and a first elastic member. The first sealing ring is movably sleeved on the first valve core. One end of the first elastic member is connected to at least one of the first housing or the first valve core, and the other end is connected to the end of the first sealing ring away from the second connector.

6. The modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device according to claim 4, characterized in that, The second connector includes: a second housing and a second sealing assembly; a second channel is formed within the second housing, and the second sealing assembly is movably disposed within the second channel; When the first connector and the second connector are plugged into each other, the second sealing assembly opens the second channel to make the first channel and the second channel communicate; when the first connector and the second connector are separated, the second sealing assembly closes the second channel.

7. The modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device according to claim 6, characterized in that, The second sealing assembly includes: The second valve core is disposed in the second channel and has a second opening; The second sealing structure is movably disposed within the second channel; when the first connector and the second connector are separated, the second sealing structure seals the second opening to cooperate with the second valve core to close the second channel; when the first connector and the second connector are inserted into each other, the first sealing structure abuts against the second sealing structure to allow the second sealing structure to open the second opening.

8. The modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device according to claim 7, characterized in that, The second valve core is cylindrical, and the second opening is located on the peripheral wall of the second valve core; The second sealing structure includes: a second sealing ring and a second elastic member. The second sealing ring is movably sleeved on the second valve core. One end of the second elastic member is connected to at least one of the second housing or the second valve core, and the other end is connected to the end of the second sealing ring away from the first plug.

9. The modular, online-replaceable extracorporeal membrane oxygenation (ECMO) device according to any one of claims 3-8, characterized in that, Also includes: A locking mechanism is disposed between the corresponding first connector and second connector; The locking mechanism can switch between locked and unlocked states; When the locking mechanism is in the locked state, the locking mechanism locks the first connector and the second connector; When the locking mechanism is in the unlocked state, the first connector and the second connector can be separated from each other.

10. The modular, online-replaceable extracorporeal membrane oxygenator according to any one of claims 9, characterized in that, Also includes: Operating components; The operating components and the membrane lung module are configured in a one-to-one correspondence; The operating components are respectively connected to the locking mechanisms corresponding to the membrane lung modules, and are used to drive the locking mechanisms to switch between the locked state and the unlocked state.

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