A clinical tumor specimen sampler and method of operation thereof

Abstract

The present application relates to the technical field of neurosurgery, and particularly relates to a clinical tumor specimen sampler, which comprises a sampling guide rod and an operation handle arranged at the tail end of the sampling guide rod, the head end of the sampling guide rod is provided with a clamping mechanism for clamping a tumor specimen, and a collecting mechanism is arranged below the clamping mechanism and connected with the sampling guide rod. Through the arrangement of the clamping mechanism, clamping and fixing during tumor tissue separation is realized, and the clamping and fixing of tumor tissues of different sizes and shapes can be achieved. Through the cooperation of the spring and the clamping ball head in the clamping mechanism, the tumor tissue will not be damaged due to excessive clamping force during the clamping process, and the technical problem that the tumor tissue cannot be clamped and fixed during the separation process in the prior art is solved. Through the arrangement of the collecting mechanism, the tumor tissue can be in a completely closed vacuum environment after collection, and the tumor tissue is prevented from being contaminated during the collection and inspection process.

Description

Technical Field

[0001] This invention relates to the field of neurosurgical technology, and in particular to a clinical tumor specimen sampler and its operation method. Background Technology

[0002] With the continuous advancement of medical technology, especially the rapid development in the field of tumor diagnosis and treatment, higher demands are being placed on the collection and processing of tumor specimens. Clinical tumor specimen extractors, as key tools in the tumor diagnosis and treatment process, directly affect the quality of the specimens and the accuracy of subsequent analysis.

[0003] During surgery, rapid and accurate collection of tumor specimens is crucial for surgical success and patient prognosis. Traditional manual sampling methods suffer from drawbacks such as complexity, inaccuracy, and susceptibility to contamination, failing to meet the efficiency and safety requirements of modern surgical procedures. Therefore, the research and development of efficient, convenient, and safe clinical tumor specimen collection devices has become an urgent need in the medical field.

[0004] During tumor surgery and biopsy, patient discomfort and complications are crucial factors that physicians must consider. The design of clinical tumor specimen retrieval devices should prioritize patient comfort, minimizing surgical trauma and complications. For example, optimizing the device's structure and operation can reduce pain during surgery and shorten postoperative recovery time.

[0005] The quality of tumor specimens directly affects the accuracy of pathological diagnosis. Clinical tumor specimen extraction instruments need to ensure the integrity and representativeness of the specimen during sampling, avoiding contamination and damage. This requires the extraction instrument to have a precise sampling mechanism, reliable sealing performance, and stable operation.

[0006] With the continuous development of materials science, mechanical engineering, and electronic technology, new innovative technologies are constantly being introduced into the research and development of medical devices. Clinical tumor specimen retrieval devices also benefit from these technologies, with their performance and effectiveness continuously improved through the adoption of new materials, processes, and technologies. For example, the application of polymer materials improves the sealing and corrosion resistance of the retrieval device; the application of precision machining technology improves the accuracy and stability of the sampling mechanism; and the application of electronic technology endows the retrieval device with more intelligent functions.

[0007] A search revealed Chinese patent application number 202310224982.1, which discloses a tumor specimen retrieval device for neurosurgical clinicians. The device includes: a collection mechanism; and a negative pressure fixation mechanism, which is fixedly installed at the bottom of the collection mechanism. The negative pressure fixation mechanism includes a vacuum chamber, with an air extraction tube and a hose connector connected to it. One end of the air extraction tube is connected to a miniature air pump, one end of the hose connector is connected to a first hose, one end of the first hose is connected to a second hose, and one end of the second hose is connected to a connector. A battery is fixedly connected to the bottom of the vacuum chamber, and a controller is fixedly connected to the surface of the battery. This invention offers the advantage of stable sampling, solving the problem that existing tumor specimen retrieval devices for neurosurgical clinicians are inconvenient for adsorbing and fixing collected tumor specimens, easily causing them to fall during retrieval and reducing the stability of tumor specimen sampling.

[0008] The tumor specimen extractor in the prior art can fix the tumor specimen during the process of removing it after collection, but it cannot clamp and fix the tumor tissue during the separation of tumor tissue. Summary of the Invention

[0009] The existing tumor specimen extractor cannot clamp and fix the tumor tissue during the separation process, which may result in the tumor tissue not being able to enter the collection bag accurately and quickly or causing contamination during the collection process.

[0010] To achieve the above objectives, the technical solution adopted by the present invention is as follows: This application provides a clinical tumor specimen sampler, including a sampling guide rod and an operating handle disposed at the tail end of the sampling guide rod. The head end of the sampling guide rod is provided with a clamping mechanism for clamping the tumor specimen, and a collection mechanism is disposed below the clamping mechanism. The collection mechanism is connected to the sampling guide rod.

[0011] Furthermore, the clamping mechanism includes two clamping components with identical structures and symmetrical arrangement, and each clamping component is fixedly connected to the sampling guide rod through connecting ears.

[0012] Specifically, the clamping component includes a motor, a rotating shaft, a bearing, and grippers; The rotating shaft is fitted with a bearing, and a motor is connected to the end of the rotating shaft. The outer ring of the bearing is sleeved with a connecting lug. The gripper is fixedly connected to the rotating shaft.

[0013] More specifically, the gripper has an arc-shaped structure.

[0014] Furthermore, the clamping component also includes two sleeves disposed inside each gripper, each sleeve containing a spring, the end of which is connected to a clamping ball head, which is slidably connected to the sleeve.

[0015] In particular, the clamping ball head is made of silicone material, and the combination of the silicone clamping ball head and the spring creates a soft and gentle clamping force when in contact with the tumor specimen, without damaging the specimen.

[0016] In the above technical solution, the collection mechanism includes a bag opening control component and a collection bag detachably connected to the bag opening control component, and the bag opening control component is connected to the sampling guide rod.

[0017] In detail, the bag opening control component includes a fixing block, a second motor, a threaded rod, a slider, a hook, and a connecting bracket; The fixing block is fixedly connected to the sampling guide rod, and a second motor is connected to the fixing block; a threaded rod is connected to the output end of the second motor, and a slider is threadedly fitted on the threaded rod. The slider is slidably connected to the sampling guide rod, and a hook is provided on the slider; the end of the threaded rod is rotatably connected to a connecting bracket, one end of the connecting bracket is fixedly connected to the sampling guide rod, and the other end is inserted into the collection bag.

[0018] Preferably, the bottom of the slider is provided with a groove, and the bottom of the sampling guide rod is provided with a slide rail. The groove and the slide rail cooperate to realize the back-and-forth movement of the slider on the sampling guide rod.

[0019] More specifically, the collection bag includes an outer bag and an inner bag fitted inside the outer bag. The outer bag is provided with a pull rope, and a connecting block is movably threaded through the pull rope and its end is hooked to a hook. The connecting block is fixed to the connecting bracket by screws.

[0020] It should be noted that the upper opening of the inner bag extends along the edge to cover the upper opening of the outer bag.

[0021] Preferably, the inner bag is connected to a vacuum pump for shrinking the inner bag.

[0022] Preferably, a camera is provided at the head end of the sampling guide rod, and the camera is electrically connected to a display screen connected to the sampling guide rod.

[0023] A method for operating a clinical tumor specimen sampler includes the following steps: S1: Adjust the collection mechanism to make the collection bag in a semi-closed state; S2: The tumor specimen is clamped and fixed by the clamping mechanism; S3: After the tumor specimen is separated, the clamping mechanism releases its grip on the tumor specimen, and the tumor specimen enters the collection bag and the bag opening is completely closed.

[0024] Compared with the prior art, the beneficial effects of the present invention are: 1. This invention uses a motor to drive a rotating shaft to rotate, which in turn drives two grippers to move closer together to achieve a clamping effect. Furthermore, the spring inside the inner sleeve of the gripper and the setting of the clamping ball head can achieve stable clamping and fixation of the tumor specimen. The combination of the silicone clamping ball head and the spring creates a soft and buffered clamping force when in contact with the tumor specimen, without damaging the specimen.

[0025] 2. This invention uses a second motor to drive a threaded rod to rotate, which in turn causes the slider to move back and forth, pulling the hook and causing the outer bag to shrink. The shrinkage of the outer bag causes the inner bag opening to completely close and seal. Furthermore, a vacuum pump at the bottom of the inner bag creates a vacuum state in the inner bag, thereby avoiding the problem of contamination of the collected tumor specimens.

[0026] 3. The present invention uses the detachable connection between the outer bag and the connecting bracket, and the detachable fixation between the connecting block on the pull rope and the connection via screws, to facilitate the removal of the collection bag after the tumor specimen collection is completed, and the inner bag can be taken out separately and sent for testing together with the tumor specimen inside, thus avoiding specimen contamination during the testing process.

[0027] 4. This invention uses a camera installed at the head of the sampling guide rod to transmit the image of the tumor tissue cutting process to a display screen. Medical staff can quickly locate the precise position of the tumor specimen and collect it by gripping it during operation. Attached Figure Description

[0028] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0029] Figure 1 This is a perspective view of the overall structure of the present invention; Figure 2 For the present invention Figure 1 Top view; Figure 3 For the present invention Figure 1 The main view; Figure 4 For the present invention Figure 3 Sectional view along the AA direction; Figure 5 This is a perspective view of the clamping component structure of the present invention; Figure 6 For the present invention Figure 5Middle front view; Figure 7 For the present invention Figure 6 Sectional view along the BB direction; Figure 8 This is a perspective view of the collection bag structure of the present invention; Figure 9 For the present invention Figure 8 Middle front view; Figure 10 For the present invention Figure 9 Sectional view along the CC direction; Figure 11 For the present invention Figure 9 Mid-top view; Figure 12 For the present invention Figure 11 Sectional view along the DD direction; In the diagram: 1. Sampling guide rod; 2. Operating handle; 3. Clamping mechanism; 31. Clamping component; 311. Motor 1; 312. Rotating shaft; 313. Bearing; 314. Gripper; 315. Sleeve; 316. Spring; 317. Clamping ball head; 32. Connecting ear; 4. Collection mechanism; 41. Bag opening control component; 411. Fixing block; 412. Motor 2; 413. Threaded rod; 414. Slider; 415. Hook; 416. Connecting bracket; 42. Collection bag; 421. Outer bag; 422. Inner bag; 423. Pull-out rope; 424. Connecting block; 5. Camera; 6. Display screen. Detailed Implementation

[0030] To enable those skilled in the art to better understand the technical solutions of the present invention, the technical solutions of the present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0031] In the description of this invention, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "front end", "rear end", "inner side", "outer side", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0032] In the description of this application, it should also be noted that, unless otherwise expressly specified and limited, the terms "set up," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal communication between two components. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0033] The inventors discovered that tumor specimens require clamping and fixation during the cutting and separation process. Due to differences in tumor type, location, and size, different types of sampling instruments are needed to adapt to varying sampling requirements. Furthermore, the obtained tumor specimens need immediate fixation and preservation to ensure the effectiveness of subsequent testing. However, in practice, the complexity of specimen processing and stringent preservation conditions can lead to insufficient fixation and improper preservation, thus affecting the accuracy of test results.

[0034] Based on the above findings, this application provides a clinical tumor specimen sampler, including a sampling guide rod 1 and an operating handle 2 disposed at the tail end of the sampling guide rod 1. The head end of the sampling guide rod 1 is provided with a clamping mechanism 3 for clamping the tumor specimen, and a collection mechanism 4 is disposed below the clamping mechanism 3. The collection mechanism 4 is connected to the sampling guide rod 1. Example 1

[0035] Reference Figure 1-7 As shown, during tumor segmentation, it is necessary to clamp and fix the tumor tissue in order to better separate the tumor tissue. This application provides a clinical tumor specimen sampler, including a sampling guide rod 1 and an operating handle 2 disposed at the tail end of the sampling guide rod 1. The head end of the sampling guide rod 1 is provided with a clamping mechanism 3 for clamping the tumor specimen.

[0036] Furthermore, the clamping mechanism 3 includes two clamping components 31 with identical structures and symmetrical arrangement. Each clamping component 31 is fixedly connected to the sampling guide rod 1 via a connecting ear 32.

[0037] Specifically, the clamping component 31 includes a motor 311, a rotating shaft 312, a bearing 313, and a gripper 314; The rotating shaft 312 is fitted with a bearing 313, and a motor 311 is connected to the end of the rotating shaft 312. The outer ring of the bearing 313 is fitted with a connecting lug 32. The gripper 314 is fixedly connected to the rotating shaft 312.

[0038] It should be noted that when the motor 311 starts, the shaft 312 rotates. The bearing 313 is designed so that the inner ring of the bearing 313 rotates with the shaft 312, while the outer ring connected by the connecting ear 32 does not rotate. The gripper 314 also rotates with the shaft 312, thereby bringing the two grippers 314 closer together to achieve clamping and fixing.

[0039] More specifically, the clamping component 31 further includes two sleeves 315 disposed inside each gripper 314, each sleeve 315 being provided with a spring 316, the end of the spring 316 being connected to a clamping ball head 317, the clamping ball head 317 being slidably connected to the sleeve 315.

[0040] Preferably, the clamping ball head 317 is made of silicone material. Since the size and shape of tumor tissues vary, the shape of the clamping claw 314 is fixed. During the tightening process, it cannot be guaranteed that the tumor tissue will be completely clamped and fixed. Furthermore, excessive compression of the clamping claw 314 may damage the tumor tissue. However, through the cooperation of the spring 316 and the clamping ball head 317, the silicone ball at the front end will contact the tumor tissue first during the clamping process. The setting of the silicone clamping ball head 317 and the spring 316 forms a buffered and gentle clamping force when contacting the tumor specimen, which will not damage the specimen. Example 2

[0041] Based on Example 1, referring to Figure 1-4 As shown in Figures 8-12, after the tumor tissue is completely separated, it needs to be collected, preserved, and sent for testing. Therefore, a collection mechanism 4 is provided below the clamping mechanism 3, and the collection mechanism 4 is connected to the sampling guide rod 1. This enables the collection and fixation of the tumor specimen.

[0042] Furthermore, the collection mechanism 4 includes a bag opening control component 41 and a collection bag 42 detachably connected to the bag opening control component 41, wherein the bag opening control component 41 is connected to the sampling guide rod 1.

[0043] In detail, the bag opening control component 41 includes a fixing block 411, a motor 412, a threaded rod 413, a slider 414, a hook 415, and a connecting bracket 416; The fixing block 411 is fixedly connected to the sampling guide rod 1, and a motor 412 is connected to the fixing block 411; The output end of the second motor 412 is connected to a threaded rod 413, and a slider 414 is threadedly fitted on the threaded rod 413. The slider 414 is slidably connected to the sampling guide rod 1, and a hook 415 is provided on the slider 414. Preferably, the bottom of the slider 414 is provided with a groove, and the bottom of the sampling guide rod 1 is provided with a slide rail. The groove and the slide rail cooperate to realize the back-and-forth movement of the slider 414 on the sampling guide rod 1.

[0044] The end of the threaded rod 413 is rotatably connected to the connecting bracket 416. One end of the connecting bracket 416 is fixedly connected to the sampling guide rod 1, and the other end is inserted into the collection bag 42. This insertion connection method facilitates the removal of the specimen for testing after collection.

[0045] As an example, the collection bag 42 includes an outer bag 421 and an inner bag 422 fitted inside the outer bag 421. The outer bag 421 is provided with a pull rope 423. A connecting block 424 is movably threaded through the pull rope 423 and its end is hooked to a hook 415. The connecting block 424 is fixed to the connecting bracket 416 by screws.

[0046] It should be noted that the upper opening of the inner bag 422 extends along the edge to cover the upper opening of the outer bag 421, so that when the outer bag 421 is contracted by pulling the drawstring 423, the inner bag 422 can be completely contracted and sealed, which facilitates the preservation of tumor specimens and avoids contamination of tumor specimens.

[0047] Preferably, the bottom of the inner bag 422 is made of memory foam material, which can cushion the fall of the tumor specimen and prevent damage to the specimen during the process of entering the inner bag 422.

[0048] More preferably, in order to further improve the preservation environment of the tumor specimen, a vacuum pump is connected to the inner bag 422 to cause the inner bag 422 to contract, so that the tumor specimen is in a vacuum environment.

[0049] It should be noted that the vacuum pump in question is existing technology, and the inventor has not made any improvements. Example 3

[0050] Based on Embodiment 1 and Embodiment 2, referring to Figure 1-2 As shown, in order to facilitate medical staff to operate under visualization when collecting tumor specimens and thus improve the accuracy of the operation, a camera 5 is set at the head end of the sampling guide rod 1. The camera 5 is electrically connected to the display screen 6 connected to the sampling guide rod 1.

[0051] It should be noted that the camera 5 and the display screen 6 are existing technologies, and the inventor has not made any improvements. Specific application examples:

[0052] The use of a clinical tumor specimen sampler according to this application in specific operation is now described in detail with reference to Embodiment 1, Embodiment 2 and Embodiment 3.

[0053] During tumor resection surgery, the entire device is moved to the location of the tumor with the help of camera 5 and display screen 6.

[0054] By pressing the button on the sampling guide rod 1, the motor 311 is started. The motor 311 drives the rotating shaft 312 to rotate, thereby driving the two grippers 314 to move closer to each other to achieve the clamping effect.

[0055] During the clamping process of the grippers 314 closing and tightening, the tumor tissue first contacts the clamping ball head 317 located inside the grippers 314. As the clamping process intensifies, the clamping ball head 317 compresses the spring 316. Through the spring 316 within the inner sleeve 314 of the grippers 314 and the clamping ball head 317, stable clamping and fixation of tumor specimens of different sizes and shapes can be achieved. Furthermore, the coordinated arrangement of the silicone clamping ball head 317 and the spring 316 creates a soft and buffered clamping force upon contact with the tumor specimen, preventing damage to the specimen.

[0056] After the tumor tissue is completely separated, pressing another button on the sampling guide rod 1 activates motor 2 412. Motor 2 412 drives the threaded rod 413 to rotate, and then the slider 414 moves along the sampling guide rod 1 towards the operating handle 2 through the threaded engagement between the slider 414 and the threaded rod 413. The movement of the slider 414 in turn drives the hook 415 to pull the pull rope 423, causing the outer bag 421 to shrink. The shrinkage of the outer bag 421 causes the opening of the inner bag 422 to be completely sealed. Furthermore, the vacuum pump at the bottom of the inner bag 422 keeps the inner bag 422 in a vacuum state, thereby avoiding the problem of contamination of the collected tumor specimen.

[0057] After the tumor specimen collection is completed, the connecting block 424 and the connecting support 416 are separated by untying the pull rope 423 and the hook 415, and the screw on the connecting block 424 is unscrewed. The connecting support 416 is then pulled out from the outer bag 421, causing the outer bag 421 to separate as a whole. The inner bag 422 inside the outer bag 421 and the tumor tissue in the inner bag 422 can then be taken out and sent for testing.

[0058] It should be noted that those skilled in the art can make various modifications and improvements without departing from the structure of this invention, and these should also be considered within the scope of protection of this invention. These modifications and improvements will not affect the effectiveness of the invention or the practicality of the patent. The scope of protection claimed in this application shall be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A clinical tumor specimen sampler, comprising a sampling guide rod (1) and an operating handle (2) disposed at the tail end of the sampling guide rod (1), characterized in that: The sampling guide rod (1) is provided with a clamping mechanism (3) for clamping tumor specimens at its head end, and a collection mechanism (4) is provided below the clamping mechanism (3), which is connected to the sampling guide rod (1).

2. The clinical tumor specimen sampler according to claim 1, characterized in that: The clamping mechanism (3) includes two clamping components (31) with the same structure and symmetrical arrangement. The clamping components (31) are fixedly connected to the sampling guide rod (1) through connecting ears (32).

3. A clinical tumor specimen sampler according to claim 2, characterized in that: The clamping component (31) includes a motor (311), a rotating shaft (312), a bearing (313), and a gripper (314). The rotating shaft (312) is fitted with a bearing (313), and the end of the rotating shaft (312) is connected to a motor (311), and the outer ring of the bearing (313) is fitted with a connecting lug (32); The gripper (314) is fixedly connected to the rotating shaft (312).

4. A clinical tumor specimen sampler according to claim 3, characterized in that: The clamping component (31) further includes two sleeves (315) disposed inside each gripper (314), each sleeve (315) being provided with a spring (316), the end of the spring (316) being connected to a clamping ball head (317), the clamping ball head (317) being slidably connected to the sleeve (315).

5. A clinical tumor specimen sampler according to claim 4, characterized in that: The collection mechanism (4) includes a bag opening control component (41) and a collection bag (42) detachably connected to the bag opening control component (41), wherein the bag opening control component (41) is connected to the sampling guide rod (1).

6. A clinical tumor specimen sampler according to claim 5, characterized in that: The bag opening control component (41) includes a fixing block (411), a second motor (412), a threaded rod (413), a slider (414), a hook (415), and a connecting bracket (416). The fixing block (411) is fixedly connected to the sampling guide rod (1), and the fixing block (411) is connected to the motor (412). The output end of the second motor (412) is connected to a threaded rod (413), and a slider (414) is threadedly fitted on the threaded rod (413). The slider (414) is slidably connected to the sampling guide rod (1), and a hook (415) is provided on the slider (414). The end of the threaded rod (413) is rotatably connected to the connecting bracket (416). One end of the connecting bracket (416) is fixedly connected to the sampling guide rod (1), and the other end is inserted into the collection bag (42).

7. A clinical tumor specimen sampler according to claim 6, characterized in that: The collection bag (42) includes an outer bag (421) and an inner bag (422) fitted inside the outer bag (421). The outer bag (421) is provided with a pull rope (423). A connecting block (424) is movably threaded through the pull rope (423) and its end is hooked to a hook (415). The connecting block (424) is fixed to the connecting bracket (416) by screws.

8. A clinical tumor specimen sampler according to claim 7, characterized in that: A vacuum pump is connected to the inner bag (422) for causing the inner bag (422) to contract.

9. A clinical tumor specimen sampler according to claim 8, characterized in that: The sampling guide rod (1) is equipped with a camera (5) at its head end, and the camera (5) is electrically connected to a display screen (6) connected to the sampling guide rod (1).

10. The method of operating a clinical tumor specimen sampler according to claim 9, characterized in that, Includes the following steps: S1: Adjust the collection mechanism (4) so ​​that the collection bag (42) is in a semi-closed state; S2: The tumor specimen is clamped and fixed by the clamping mechanism (3); S3: After the tumor specimen is separated, the clamping mechanism (3) releases the clamp on the tumor specimen, and the tumor specimen enters the collection bag (42) and then completely closes the bag opening.

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