Sample testing apparatus, sample testing method
Patent Information
- Application Number
- CN202510421372.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-03
- Publication Date
- 2026-10-16
AI Technical Summary
由于不同检测模式的检测动作不同,不同检测模式的检测时序难以进行叠加,导致现有的样本检测设备通常不会在不同检测模式的检测时序进行叠加,样本检测设备的检测速度受限
[0015] This application provides a sample detection device and a sample detection method. The sample detection device includes a sample introduction component, a detection component, and a processor. The sample introduction component is used to acquire a sample to be tested. The detection component is connected to the sample introduction component and is used to detect the sample to be tested under at least two detection modes. The processor is connected to the detection component and stores detection timing sequences corresponding to at least two detection modes. The processor is used to superimpose the detection timing sequences of the same detection mode to detect the sample to be tested when the detection component performs detection under the same detection mode. The processor is also used to superimpose the detection timing sequences of different detection modes to detect the sample to be tested when the detection component performs detection under different detection modes. The superimposed segments of the detection timing sequences of the same detection mode and the superimposed segments of the detection timing sequences of different detection modes are different. Therefore, the sample detection device of this application sets the superposition segment of the detection time sequence of the same detection mode and the superposition segment of the detection time sequence of different detection modes to be different, so that the superposition segment of the detection time sequence of the same detection mode and the superposition segment of the detection time sequence of different detection modes will not conflict with each other in the detection time sequence, thereby ensuring the superposition stability and reliability of the detection time sequence of different detection modes, and thus improving the detection speed of the sample detection device.
Smart Images

Figure CN122922397A_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of sample testing technology, and in particular to sample testing equipment and sample testing methods. Background Technology
[0002] To meet the testing needs of sample testing equipment for different combinations of items, existing sample testing equipment usually has multiple testing modes for different combinations of items.
[0003] To improve detection speed, existing sample testing equipment typically incorporates overlay segments into the sample detection time sequence within the same mode. However, when receiving multiple samples for testing, the detection modes for these samples often differ, necessitating interleaved testing across different modes and requiring the equipment to switch between them. Because the detection actions differ across modes, the detection time sequences of these modes are difficult to overlay, thus limiting the detection speed of existing sample testing equipment. Summary of the Invention
[0004] To address the aforementioned technical problems, this application provides sample testing equipment and sample testing methods.
[0005] To address the aforementioned problems, this application provides a first technical solution: a sample detection device, including a sample introduction component, a detection component, and a processor; the sample introduction component is used to acquire a sample to be tested; the detection component is connected to the sample introduction component and is used to detect the sample to be tested under at least two detection modes; the processor is connected to the detection component and stores detection timing sequences corresponding to the at least two detection modes, the detection timing sequences including a first superposition timing sequence and a second superposition timing sequence; the processor is used to superimpose the detection timing sequences of the same detection mode to detect the sample to be tested when the detection component performs detection under the same detection mode; the processor is also used to superimpose the detection timing sequences of different detection modes to detect the sample to be tested when the detection component performs detection under different detection modes; wherein the superposition segment of the detection timing sequence under the same detection mode and the superposition segment of the detection timing sequence under different detection modes are different.
[0006] Optionally, the sample introduction component is used to acquire a first test sample and a second test sample, and to acquire sample information of the first test sample and the second test sample; the processor is used to superimpose the detection timing of the detection mode when the sample information indicates that the detection mode of the first test sample and the second test sample is the same detection mode; the processor is also used to superimpose the detection timing of the detection mode corresponding to the second test sample into the detection timing of the detection mode corresponding to the first test sample when the sample information indicates that the detection mode of the first test sample and the second test sample is different detection modes.
[0007] Optionally, the detection component includes at least a first detection mode and a second detection mode. The processor stores a first timing sequence corresponding to the first detection mode and a second timing sequence corresponding to the second detection mode. The processor is configured to, when the sample information indicates that the detection mode of the first sample to be tested and the second sample to be tested is the first detection mode, call a first overlay segment in the first timing sequence to detect the second sample to be tested, so that adjacent first timing sequences are overlaid in the first overlay segment. The processor is further configured to, when the sample information indicates that the detection mode of the first sample to be tested is the first detection mode and the detection mode of the second sample to be tested is the second detection mode, call a second overlay segment in the first timing sequence to detect the second sample to be tested, so that the first timing sequence and the second timing sequence are overlaid in the second overlay segment. The position of the first overlay segment in the first timing sequence is different from the position of the second overlay segment in the first timing sequence.
[0008] Optionally, the position of the first superimposed segment in the first time sequence and the position of the second superimposed segment in the first time sequence partially overlap; and / or, the start time of the first superimposed segment in the first time sequence is a first time, the start time of the second superimposed segment in the first time sequence is a second time, and the first time is earlier than the second time.
[0009] Optionally, the processor is configured to, when the sample information indicates that the detection mode of the first sample to be tested and the second sample to be tested is the second detection mode, invoke a third overlay segment in the second timing sequence to detect the second sample to be tested, so that adjacent second timing sequences are overlaid in the third overlay segment; the processor is further configured to, when the sample information indicates that the detection mode of the first sample to be tested is the second detection mode and the detection mode of the second sample to be tested is the first detection mode, invoke a fourth overlay segment in the second timing sequence to detect the second sample to be tested, so that the second timing sequence and the first timing sequence are overlaid in the fourth overlay segment; wherein the position of the third overlay segment in the second timing sequence is different from the position of the fourth overlay segment in the second timing sequence.
[0010] Optionally, the positions of the third and fourth overlay segments in the second time series do not overlap; and / or, the start time of the third overlay segment in the second time series is the third time, the start time of the fourth overlay segment in the second time series is the fourth time, and the third time is earlier than the fourth time.
[0011] Optionally, the detection component further includes a third detection mode, and the processor further stores a third timing sequence corresponding to the third detection mode; the processor is further configured to, when the sample information indicates that the detection mode of the first sample to be tested is the first detection mode and the detection mode of the second sample to be tested is the third detection mode, call a fifth overlay segment in the first timing sequence to detect the second sample to be tested, so that the first timing sequence and the third timing sequence are overlaid in the fifth overlay segment; wherein the positions of the first overlay segment, the second overlay segment and the fifth overlay segment in the first timing sequence are different.
[0012] Optionally, the sample introduction component includes a scanning mechanism, and the processor is connected to the scanning mechanism. The scanning mechanism is used to receive a first sample tube storing the first sample to be tested and a second sample tube storing the second sample to be tested. The scanning mechanism is also used to scan the first sample tube to obtain first sample information of the first sample to be tested, and to scan the second sample tube to obtain second sample information of the second sample to be tested. The processor is used to control the detection timing of the detection modes indicated by the first sample information and the second sample information to be superimposed at the first detection node when they are the same. The processor is used to control the detection timing of different detection modes to be superimposed at the second detection node when the detection modes indicated by the first sample information and the second sample information are different. The first detection node is earlier than the second detection node.
[0013] Optionally, the start time of the overlay segment of the first detection node is the fifth time, and the time when the scanning mechanism acquires the first sample information and the second sample information is the sixth time, the sixth time being earlier than the fifth time; and / or, the start time of the overlay segment of the second detection node is the seventh time, and the time when the scanning mechanism acquires the first sample information and the second sample information is the sixth time, the sixth time being earlier than the seventh time.
[0014] To address the aforementioned problems, this application provides a second technical solution: a sample detection method comprising: acquiring a sample to be tested; when the detection components perform detection using the same detection mode, superimposing the detection timing sequences of the same detection mode to detect the sample to be tested; and when the detection components perform detection using different detection modes, superimposing the detection timing sequences of different detection modes to detect the sample to be tested; wherein the superimposed segment of the detection timing sequences of the same detection mode and the superimposed segment of the detection timing sequences of different detection modes are different.
[0015] This application provides a sample detection device and a sample detection method. The sample detection device includes a sample introduction component, a detection component, and a processor. The sample introduction component is used to acquire a sample to be tested. The detection component is connected to the sample introduction component and is used to detect the sample to be tested under at least two detection modes. The processor is connected to the detection component and stores detection timing sequences corresponding to at least two detection modes. The processor is used to superimpose the detection timing sequences of the same detection mode to detect the sample to be tested when the detection component performs detection under the same detection mode. The processor is also used to superimpose the detection timing sequences of different detection modes to detect the sample to be tested when the detection component performs detection under different detection modes. The superimposed segments of the detection timing sequences of the same detection mode and the superimposed segments of the detection timing sequences of different detection modes are different. Therefore, the sample detection device of this application sets the superposition segment of the detection time sequence of the same detection mode and the superposition segment of the detection time sequence of different detection modes to be different, so that the superposition segment of the detection time sequence of the same detection mode and the superposition segment of the detection time sequence of different detection modes will not conflict with each other in the detection time sequence, thereby ensuring the superposition stability and reliability of the detection time sequence of different detection modes, and thus improving the detection speed of the sample detection device. Attached Figure Description
[0016] To more clearly illustrate the technical solutions in the embodiments of this application, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Wherein:
[0017] Figure 1 This is a schematic diagram of the structure of an embodiment of the sample detection device provided in this application;
[0018] Figure 2 This is a schematic diagram of the superposition method of the detection timing of the sample detection device provided in this application;
[0019] Figure 3 yes Figure 1 A schematic diagram of the structure of one embodiment of the detection component;
[0020] Figure 4 This is a timing diagram of the sample detection device provided in this application in CD mode;
[0021] Figure 5 This is a timing diagram of the sample detection device provided in this application in CDC mode;
[0022] Figure 6 This is a flowchart illustrating an embodiment of the sample detection method provided in this application. Detailed Implementation
[0023] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.
[0024] It should be noted that if the embodiments of this application involve directional indicators (such as up, down, left, right, front, back, etc.), the directional indicators are only used to explain the relative positional relationship and movement of the components in a certain specific posture (as shown in the figure). If the specific posture changes, the directional indicators will also change accordingly.
[0025] Furthermore, if the embodiments of this application involve descriptions such as "first" or "second," these descriptions are for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, features defined with "first" or "second" may explicitly or implicitly include at least one of those features. Additionally, the technical solutions of various embodiments can be combined with each other, but this must be based on the ability of those skilled in the art to implement them. If the combination of technical solutions is contradictory or impossible to implement, it should be considered that such a combination of technical solutions does not exist and is not within the scope of protection claimed in this application.
[0026] Please see Figure 1 , Figure 1This is a schematic diagram of the structure of one embodiment of the sample detection device provided in this application. Figure 1 As shown, this application embodiment first provides a sample detection device, which includes a sample injection component, a detection component, and a processor.
[0027] The sample introduction component is used to acquire the sample to be tested; the detection component is connected to the sample introduction component and is used to detect the sample to be tested in at least two detection modes; the processor is connected to the detection component and stores the detection timing corresponding to at least two detection modes. The processor is used to superimpose the detection timing of the same detection mode to detect the sample to be tested when the detection component performs detection in the same detection mode; the processor is also used to superimpose the detection timing of different detection modes to detect the sample to be tested when the detection component performs detection in different detection modes; the superimposed segment of the detection timing of the same detection mode and the superimposed segment of the detection timing of different detection modes are different.
[0028] Specifically, the detection component includes at least two detection modes. When the detection component uses the same detection mode, it can be understood as performing continuous testing using the same detection mode across two consecutive detection periods, without switching detection modes. Conversely, when the detection component uses different detection modes, it can be understood as performing continuous testing using different detection modes across two consecutive detection periods, by switching from one detection mode to another between the two periods.
[0029] Because the detection timings corresponding to the same detection mode are identical—meaning the detection actions performed by the detection components at a given timing node are the same under the same detection mode—overlaying detection timings under the same detection mode only requires considering action conflicts within the current timing sequence. For example, while one detection action in the current detection mode is being executed, the next sample test, which does not conflict with that action, can be performed simultaneously to achieve overlay. However, because the combinations of detection items differ across detection modes, the detection nodes and actions of the corresponding detection timings are also different. Therefore, overlaying different detection modes requires considering action conflicts between the two timing sequences, meaning that overlaying different detection modes cannot be directly performed on the existing overlay segment of the same detection mode. Consequently, the overlay segment for detection timings under the same detection mode is different from the overlay segment for detection timings under different detection modes.
[0030] For example, two detection periods can be understood as two samples to be tested that are injected consecutively, or as two batches of samples to be tested. For example, the sample detection device can continuously receive two samples to be tested, and the detection modes required for the two samples to be tested are the same or different. Alternatively, the sample detection device can continuously receive two batches of samples to be tested, and the detection modes required for the two batches of samples to be tested are the same or different.
[0031] The aforementioned detection modes can be understood as different operating methods or parameter settings adopted by the sample detection equipment when performing blood cell detection. A detection mode can consist of one or more detection items. For example, detection modes include, but are not limited to, at least one of the following: Complete Differential (CD) detection mode, Complete Differential Count (CDC) detection mode, Reticulocyte (RET) detection mode, and Platelet (PLT) mode.
[0032] In this embodiment of the application, the sample detection device sets the superposition segments of the detection timing sequence of the same detection mode and the superposition segments of the detection timing sequence of different detection modes to be different, so that the superposition segments of the detection timing sequence of the same detection mode and the superposition segments of the detection timing sequence of different detection modes will not conflict with each other in the detection timing sequence, thereby ensuring the superposition stability and reliability of the detection timing sequence of different detection modes, and thus improving the detection speed of the sample detection device.
[0033] In one embodiment, the sample introduction component is used to acquire a first test sample and a second test sample, as well as to acquire sample information of the first and second test samples. The sample information records relevant information about the test samples, including but not limited to at least one of the following: sample number, patient information, test item, sample type, test mode, test requirements, collection time, and processing status. Therefore, the sample detection device of this embodiment can acquire sample information of the first and second test samples through the sample introduction component, and thus obtain the corresponding test mode for the first and second test samples through the sample information.
[0034] The processor is used to superimpose the detection timing of the detection mode when the sample information indicates that the detection mode of the first sample to be tested and the second sample to be tested is the same detection mode; the processor is also used to superimpose the detection timing of the detection mode corresponding to the second sample to be tested into the detection timing of the detection mode corresponding to the first sample to be tested when the sample information indicates that the detection mode of the first sample to be tested and the second sample to be tested are different detection modes.
[0035] Specifically, when the sample information indicates that the detection modes of the first and second samples to be tested are the same, meaning the detection component needs to sequentially detect the first and second samples using the same detection mode, the processor superimposes the detection timings of the detection modes corresponding to the first and second samples to simultaneously execute a detection action of the second sample during the detection of the first sample. Conversely, when the sample information indicates that the detection modes of the first and second samples to be tested are different, meaning the detection component needs to switch from one detection mode to another after detecting the first sample to detect the second sample, the processor superimposes the two detection timings of the detection modes corresponding to the first and second samples to simultaneously execute a detection action of the second sample during the detection of the first sample.
[0036] Furthermore, the timing sequence in which a certain detection action of the second sample is performed simultaneously during the detection of the first sample can be defined as the superposition segment of the detection timing sequence. The superposition segment of the detection timing sequence under the same detection mode is different from the superposition segment of the detection timing sequence under different detection modes.
[0037] Optionally, please see Figure 2 , Figure 2 This is a schematic diagram of the superposition method of the detection timing sequence of the sample detection device provided in this application. For example... Figure 2 As shown, the detection component includes at least a first detection mode and a second detection mode. The processor stores a first timing sequence corresponding to the first detection mode and a second timing sequence corresponding to the second detection mode. The processor is used to call a first overlay segment in the first timing sequence to detect the second sample when the sample information indicates that the detection mode of the first sample to be tested and the second sample to be tested is the first detection mode, so that adjacent first timing sequences are overlaid in the first overlay segment. The processor is also used to call a second overlay segment in the first timing sequence to detect the second sample to be tested when the sample information indicates that the detection mode of the first sample to be tested is the first detection mode and the detection mode of the second sample to be tested is the second detection mode, so that the first timing sequence and the second timing sequence are overlaid in the second overlay segment.
[0038] Specifically, the first detection mode and the second detection mode correspond to different detection modes of the detection component. The first timing sequence corresponding to the first detection mode is used to indicate the execution order and timing of each detection action under that detection mode, and the second timing sequence corresponding to the second detection mode is used to indicate the execution order and timing of each detection step under that detection mode. For example, when the first detection mode is CD mode, the first timing sequence corresponding to the first detection mode may include, but is not limited to, actions such as: sample sampling, separation and washing, sample dilution, mixing and reaction, cell counting (e.g., counting of red blood cells, white blood cells and platelets), white blood cell classification, data processing and output of detection results; when the second detection mode is CDC mode, the second timing sequence corresponding to the second detection mode may include, but is not limited to, actions such as: sample sampling, separation and washing, sample dilution, mixing and reaction, cell counting (e.g., counting of red blood cells, white blood cells and platelets), C-reactive protein (CRP) detection, white blood cell classification, data processing and output of detection results.
[0039] After acquiring the sample information from the sample introduction component, the processor, when the sample information indicates that the detection mode for the first and second samples to be tested is the first detection mode, calls a first overlay segment in the first timing sequence to detect the second sample to be tested, so that adjacent first timing sequences are overlaid in the first overlay segment. The first overlay segment is a timing overlay segment of two adjacent samples to be tested in the first timing sequence. In the first overlay segment, the detection component simultaneously executes different detection actions for the first and second samples to be tested in the first timing sequence, so that the detection actions for the first and second samples to be tested do not conflict with each other.
[0040] The processor is further configured to, when the sample information indicates that the detection mode of the first sample under test is the first detection mode and the detection mode of the second sample under test is the second detection mode, invoke a second overlay segment in the first timing sequence to detect the second sample under test, so that the first timing sequence and the second timing sequence are overlaid in the second overlay segment. The second overlay segment is an overlay segment that overlays the first timing sequence of the first sample under test with the second timing sequence of the second sample under test; in the second overlay segment, the detection component simultaneously executes the detection action of the first sample under test in the first timing sequence and the detection action of the second sample under test in the second timing sequence, and the detection actions of the first sample under test and the second sample under test do not conflict with each other.
[0041] When the detection component performs detection of adjacent samples using the first detection mode, it only needs to find a time segment in the first time sequence that can perform other detection actions without affecting the current detection process to overlay the first overlay segment. Since the timing order and time intervals of each detection action differ between the first and second detection modes, when the detection component performs detection of adjacent samples using the first and second detection modes respectively, it is necessary to consider whether there are conflicts in the detection order and timing between the first and second time sequences. That is, it is necessary to find a time segment in the first time sequence that can execute a certain detection action of the second time sequence to overlay the second overlay segment. The differences between the first and second time sequences under different detection modes mean that the first and second overlay segments cannot be shared; the position of the first overlay segment in the first time sequence and the position of the second overlay segment in the second time sequence are different. Therefore, the overlay segment of the detection time sequence within the same detection mode is different from the overlay segment of the detection time sequences of different detection modes.
[0042] In this embodiment, the processor of the sample detection device is configured to, when the sample information indicates that the detection mode of the first sample to be tested and the second sample to be tested is the first detection mode, invoke a first overlay segment in the first time sequence to detect the second sample to be tested, so that adjacent first time sequences are overlaid in the first overlay segment; the processor is further configured to, when the sample information indicates that the detection mode of the first sample to be tested is the first detection mode and the detection mode of the second sample to be tested is the second detection mode, invoke a second overlay segment in the first time sequence to detect the second sample to be tested, so that the first time sequence and the second time sequence are overlaid in the second overlay segment. Therefore, the sample detection device of this embodiment can, by designing the position of the second overlay segment, allow the second overlay segment and the first overlay segment to coexist in the first time sequence without affecting each other. The processor can select the corresponding overlay segment for time sequence overlay based on the detection mode of the sample to be tested, so as to ensure the stability and reliability of the overlay of detection time sequences of different detection modes, thereby improving the detection speed of the sample detection device.
[0043] Furthermore, the positions of the first superimposed segment and the second superimposed segment in the first time series partially overlap; and / or, the start time of the first superimposed segment in the first time series is the first time, and the start time of the second superimposed segment in the first time series is the second time, with the first time being earlier than the second time.
[0044] Specifically, in one embodiment, the positions of the first overlay segment and the second overlay segment in the first time sequence partially overlap, meaning the time periods of the first overlay segment and the second overlay segment in the first time sequence intersect. For example, the start time of the first overlay segment in the first time sequence falls within the time period of the second overlay segment in the first time sequence, or the start time of the second overlay segment in the first time sequence falls within the time period of the first overlay segment in the first time sequence. In another embodiment, the start time of the first overlay segment in the first time sequence is a first time, and the start time of the second overlay segment in the first time sequence is a second time. The positions of the first overlay segment and the second overlay segment in the first time sequence partially overlap, and the first time is earlier than the second time. In yet another embodiment, the start time of the first overlay segment in the first time sequence is earlier than the start time of the second overlay segment in the first time sequence, and the end time of the first overlay segment in the first time sequence can be earlier than the start time or end time of the second overlay segment in the first time sequence, or it can fall within the time period of the second overlay segment in the first time sequence.
[0045] Understandably, because the timing order and time intervals of each detection action differ between the first and second detection modes, when the detection component performs detection on adjacent samples using the first and second detection modes respectively, it is necessary to consider whether there are conflicts in the detection order and timing between the first and second timing sequences. That is, when the first overlay segment is overlaid, it only needs to consider the conflict of detection actions in the first timing sequence, while when the second overlay segment is overlaid, it needs to consider the conflict of detection actions between the first and second timing sequences. Timing overlay can usually be achieved faster under the same detection mode. Therefore, the speed at which different detection modes begin timing overlay will be slower than the speed at which the same detection mode begins timing overlay, with the first time being earlier than the second time.
[0046] And / or, since different detection modes typically include basic detection items, and each detection item typically includes basic liquid flow processes such as sampling, separation, washing, mixing, reaction, and perfusion, when some detection actions of the second time sequence are superimposed onto the first time sequence, a portion of the first superimposed segment can also be applied to the second superimposed segment, so that the positions of the first superimposed segment and the second superimposed segment in the first time sequence partially overlap. For example, the detection component may include an optical detection mechanism. When the first detection mode is CD mode and the second detection mode is CDC mode, the first superimposed segment and the second superimposed segment can be set within the time period during which the optical detection mechanism performs white blood cell classification detection on the sample to be tested, and the first time of the first superimposed segment is earlier than the second time of the second superimposed segment, and the time period of the first superimposed segment is longer than the time period of the second superimposed segment.
[0047] In this embodiment, the sample detection device can design the positions of the first superimposed segment and the second superimposed segment in the first timing sequence to partially overlap, so that the second superimposed segment can utilize part of the detection action of the first timing sequence to test the second sample. This allows the second superimposed segment and the first superimposed segment to coexist in the first timing sequence without affecting each other. The processor can select the corresponding superimposed segment for timing superimposition based on the detection mode of the sample to be tested, so as to ensure the superimposition stability and reliability of the detection timing sequence of different detection modes, thereby improving the detection speed of the sample detection device.
[0048] Furthermore, the processor is configured to, when the sample information indicates that the detection mode of the first sample to be tested and the second sample to be tested is the second detection mode, call the third overlay segment in the second timing sequence to detect the second sample to be tested, so that the adjacent second timing sequences are overlaid in the third overlay segment; the processor is also configured to, when the sample information indicates that the detection mode of the first sample to be tested is the second detection mode and the detection mode of the second sample to be tested is the first detection mode, call the fourth overlay segment in the second timing sequence to detect the second sample to be tested, so that the second timing sequence and the first timing sequence are overlaid in the fourth overlay segment.
[0049] The third overlay segment is an overlay segment of the detection time sequences of the same detection mode, and the fourth overlay segment is an overlay segment of the detection time sequences of different detection modes. Similarly, the positions of the third overlay segment and the fourth overlay segment in the second time sequence are different. Distinguishing itself from the first overlay segment, which is an overlay segment when the first time sequences of two adjacent test samples are overlaid, and the third overlay segment is an overlay segment when the second time sequences of two adjacent test samples are overlaid, the first and third overlay segments are different. Similarly, distinguishing itself from the second overlay segment, which is an overlay segment when the second time sequence is overlaid within the first time sequence, and the fourth overlay segment is an overlay segment when the first time sequence is overlaid within the second time sequence, the second and fourth overlay segments are different.
[0050] In this case, the positions of the third and fourth overlay segments do not coincide in the second time series; and / or, the start time of the third overlay segment in the second time series is the third time, and the start time of the fourth overlay segment in the second time series is the fourth time, with the third time being earlier than the fourth time.
[0051] Specifically, when the third overlay segment is overlaid, it only needs to consider the detection action conflict of the second time sequence. When the fourth overlay segment is overlaid, it needs to consider the detection action conflict between the first time sequence and the second time sequence. Under the same detection mode, the time sequence overlay can usually be achieved faster. Therefore, the speed of time sequence overlay when different detection modes start is slower than the speed of time sequence overlay when the same detection mode starts. The third time is earlier than the fourth time.
[0052] And / or, the combination of detection items in different detection modes is different, and the detection sequence corresponding to different detection modes is different. Since different detection modes usually include basic detection items, and basic detection items usually have corresponding liquid circuit processes such as sampling, separation, cleaning, mixing, reaction, and injection, and the liquid circuit structures of the above-mentioned liquid circuit processes are intertwined, the detection actions of the first time sequence cannot be superimposed on the time points that can be superimposed between adjacent second time sequences. Therefore, the sample detection device of this embodiment can stagger the positions of the third superposition segment and the fourth superposition segment in the second time sequence, so that the third superposition segment and the fourth superposition segment will not conflict with each other in the detection time sequence, thereby ensuring the superposition stability and reliability of the detection time sequences of different detection modes, and thus improving the detection speed of the sample detection device.
[0053] Furthermore, the detection component also includes a third detection mode, and the processor also stores a third timing sequence corresponding to the third detection mode; the processor is also used to call the fifth overlay segment in the first timing sequence to detect the second sample when the sample information indicates that the detection mode of the first sample to be tested is the first detection mode and the detection mode of the second sample to be tested is the third detection mode, so that the first timing sequence and the third timing sequence are overlaid in the fifth overlay segment.
[0054] The third detection mode is a detection mode distinct from the first and second detection modes, and the fifth overlay segment is a time-series overlay segment that switches from the first detection mode to the third detection mode. The first, second, and fifth overlay segments are located in different positions within the first time sequence.
[0055] Optionally, the sample introduction component includes a scanning mechanism, and the processor is connected to the scanning mechanism. The scanning mechanism is used to receive a first sample tube storing a first sample to be tested and a second sample tube storing a second sample to be tested. The scanning mechanism is also used to scan the first sample tube to obtain first sample information of the first sample to be tested, and to scan the second sample tube to obtain second sample information of the second sample to be tested.
[0056] The processor is used to control the detection timing of the detection modes indicated by the first sample information and the second sample information to be superimposed at the first detection node when the detection modes are the same; the processor is used to control the detection timing of different detection modes to be superimposed at the second detection node when the detection modes indicated by the first sample information and the second sample information are different.
[0057] The processor can acquire first sample information of the first sample to be tested and second sample information of the second sample to be tested through a scanning mechanism. It then determines the detection mode of the first sample to be tested based on the first sample information and the detection mode of the second sample to be tested based on the second sample information. When the detection modes of the first and second sample information are the same, the processor controls the detection timing of the corresponding detection modes of the first and second samples to be tested to be superimposed at the first detection node, meaning that the detection of the first and second samples begins simultaneously at the first detection node. The processor is also used to control the detection timing of the first and second samples to be tested to be superimposed at the second detection node when the detection modes of the first and second sample information are different, meaning that the detection of the first and second samples begins simultaneously at the second detection node.
[0058] The detection sequence can include nodes for multiple detection actions. For example, in the detection sequence of a corresponding detection mode, the entire detection sequence can be divided into several detection nodes by a preset time interval, and each detection action can be associated with its corresponding detection node according to its execution time. This allows the execution order and timing of each detection action in the detection sequence to be determined through the detection nodes. Since the speed at which different detection modes are initially superimposed is slower than the speed at which the same detection mode is initially superimposed, the second detection node of the sample detection device in this embodiment is later than the first detection node. This ensures the stability and reliability of the superposition of detection sequences of different detection modes, thereby improving the detection speed of the sample detection device.
[0059] Furthermore, the start time of the overlay segment of the first detection node is the fifth time, and the time for the scanning mechanism to acquire the first sample information and the second sample information is the sixth time, which is earlier than the fifth time; and / or, the start time of the overlay segment of the second detection node is the seventh time, and the time for the scanning mechanism to acquire the first sample information and the second sample information is the sixth time, which is earlier than the seventh time.
[0060] Specifically, the processor is used to acquire first sample information and second sample information through the scanning mechanism, so as to determine whether the samples to be tested belong to the same detection mode or different detection modes based on the first sample information and the second sample information. The processor is also used to control the detection timing of the detection modes to be superimposed at the first detection node after determining that the samples to be tested belong to the same detection mode, so as to perform timing superposition of the same detection mode through the first superposition segment; the processor is also used to control the detection timing of different detection modes to be superimposed at the second detection node after determining that the samples to be tested belong to different detection modes, so as to perform timing superposition of different detection modes through the second superposition segment.
[0061] Therefore, this embodiment sets the time when the scanning mechanism acquires the first sample information and the second sample information to be earlier than the start time of the superposition segment of the first detection node, and / or sets the time when the scanning mechanism acquires the first sample information and the second sample information to be earlier than the start time of the superposition segment of the second detection node, so as to reduce or avoid missing the timing superposition at the corresponding position, thereby ensuring the superposition stability and reliability of the detection timing.
[0062] In one embodiment, please refer to Figure 3 , Figure 3 yes Figure 1 A schematic diagram of the structure of one embodiment of the detection component. (See diagram below.) Figure 3 As shown, the detection component of this embodiment includes a liquid circuit mechanism involved in the detection process. Specifically, the detection component may include a detection mechanism, a reaction mechanism, a storage mechanism, and a waste liquid mechanism connected by pipelines. The storage mechanism is used to store detection reagents; the reaction mechanism is used to realize the mixing reaction of detection reagents and test samples to obtain a test reaction solution; the detection mechanism is used to perform at least one detection on the test reaction solution, such as red blood cell count (RBC), hemoglobin (HGB), and optical detection; the waste liquid mechanism is used to store waste liquid generated during the detection process.
[0063] Optionally, the detection components may include an RBC detection mechanism, an HGB detection mechanism, and an optical detection mechanism; the reaction mechanism may include an RBC reaction cell, a DIFF reaction cell, a WNR reaction cell, and a CRP reaction cell; and the liquid storage mechanism may include a first liquid storage element, a second liquid storage element, and a third liquid storage element.
[0064] The RBC reaction cell is connected via piping to the RBC detection unit, HGB detection unit, WNR reaction cell, DIFF reaction cell, and a first reservoir. The RBC reaction cell receives the detection reagent and the sample to be tested from the first reservoir and mixes them to obtain a first reaction solution. This first reaction solution can be output to the RBC and HGB detection units for testing, or it can be output to the DIFF and WNR reaction cells for further testing. The DIFF reaction cell is connected via piping to the RBC reaction cell, optical detection unit, and a second reservoir. The DIFF reaction cell receives the detection reagent and the first reaction solution from the second reservoir and mixes them to obtain a second reaction solution, which can be output to the optical detection unit for testing. The WNR reaction cell is connected via piping to the DIFF reaction cell, RBC reaction cell, HGB detection unit, optical detection unit, and CRP reaction cell. The WNR reaction cell receives the first and second reaction solutions and mixes them to obtain a third reaction solution, which can be output to the optical detection unit or HGB detection unit for testing. The CRP reaction tank is connected to the HGB detection unit via piping, and the reaction solution from the CRP reaction tank is output to the HGB detection unit for testing. The optical detection unit is connected to a third reservoir via piping, so that the detection reagents in the third reservoir provide reagent support for the optical detection unit.
[0065] The sample introduction component may include a sampling needle. When the detection mode is CD mode, the detection sequence may include the following actions: sampling-dispensing-cleaning of the injection needle, cleaning-mixing of the RBC reaction cell, cleaning-detection of the RBC detection mechanism, cleaning-mixing of the HGB detection mechanism, cleaning-mixing of the DIFF reaction cell, cleaning-mixing-reaction of the WNR reaction cell, detection-cleaning of the optical detection mechanism, filling of the first reservoir, filling of the second reservoir, filling of the third reservoir, and waste discharge of the waste liquid mechanism. When the detection mode is CDC mode, the detection sequence may further include the cleaning-reaction of the CRP reaction cell in addition to the above-mentioned actions.
[0066] Please see Figure 4 and Figure 5 , Figure 4 This is a timing diagram of the sample detection device provided in this application in CD mode. Figure 5 This is a timing diagram of the sample detection device provided in this application in CDC mode. When the first detection mode is CD mode and the second detection mode is CDC mode, as shown... Figure 4 As shown, the first stacking segment can be stacked in the first time sequence, such as... Figure 4The CD-CD overlay segment can be set after the HGB detection mechanism operates or after the sampling needle operates; alternatively, it can be set during the operation of the optical detection mechanism. A second overlay segment can also be performed on top of the first timing sequence, such as... Figure 4 The CD-CDC overlay segment, the second overlay segment can be set after the first overlay segment.
[0067] like Figure 5 As shown, a third stacking segment can be stacked on the second time sequence, such as... Figure 5 The third superposition segment of the CDC-CDC superposition can be set after the sampling needle's movement, or during the movement of the optical detection mechanism or the CRP reaction cell. A fourth superposition segment can also be performed on the second timing sequence, such as... Figure 5 The CDC-CD overlay segment, the fourth overlay segment follows several detection nodes of the first overlay segment.
[0068] Understandably, Figure 4 and Figure 5 The detection nodes are divided into several detection nodes by time intervals. Since the detection timing of CD mode and CDC mode is different, the detection nodes and the corresponding detection actions of each detection node are different. For example, CD mode has 50 detection nodes and CDC mode has 87 detection nodes.
[0069] This application also proposes a sample detection method. Please refer to the embodiments below. Figure 6 , Figure 6 This is a schematic flowchart of an embodiment of the sample detection method provided in this application. Figure 6 As shown, in this embodiment, the sample detection method includes:
[0070] Step S10: Obtain the sample to be tested.
[0071] Specifically, the sample to be tested may be, but is not limited to, blood samples collected through a sampling tube, or blood samples that have been diluted or deagglutinated.
[0072] Step S20: When the detection components are performing detection using the same detection mode, the detection timing of the same detection mode is superimposed to detect the sample to be tested.
[0073] The aforementioned test samples include at least two consecutively detected samples. When the detection component detects the two consecutively detected samples using the same detection mode, the detection timing of the same detection mode is superimposed to detect the test samples.
[0074] Step S30: When the detection component performs detection through different detection modes, the detection timing of different detection modes is superimposed to detect the sample to be tested; wherein, the superimposed segment of the detection timing of the same detection mode is different from the superimposed segment of the detection timing of different detection modes.
[0075] The aforementioned test samples include at least two consecutively detected samples. When the detection component detects the two consecutively detected samples through different detection modes, that is, when the detection component detects the current sample through one detection mode and switches to another detection mode to detect the next sample, the detection timing of different detection modes is superimposed to detect the test samples.
[0076] Therefore, the sample detection method in this embodiment acquires the sample to be tested, and when the detection components are performing detection using the same detection mode, superimposes the detection timing sequences of the same detection mode to detect the sample to be tested. When the detection components are performing detection using different detection modes, the detection timing sequences of the different detection modes are superimposed to detect the sample to be tested. This sample detection method sets the superimposed segments of the detection timing sequences of the same detection mode and the superimposed segments of the detection timing sequences of different detection modes to be different, so that the superimposed segments of the detection timing sequences of the same detection mode and the superimposed segments of the detection timing sequences of different detection modes will not conflict with each other in the detection timing sequence, thereby ensuring the stability and reliability of the superimposed detection timing sequences of different detection modes, and thus improving the detection speed of the sample detection equipment.
[0077] The above description is merely an embodiment of this application and does not limit the patent scope of this application. Any equivalent structural or procedural transformations made using the content of this application's specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this application.
Claims
1. A sample testing device, characterized in that, include: Sample introduction assembly, used to acquire the sample to be tested; A detection component, connected to the sample introduction component, is used to detect the sample to be tested in at least two detection modes; A processor, connected to the detection component, stores detection timing sequences corresponding to the at least two detection modes. The processor is configured to, when the detection component performs detection using the same detection mode, superimpose the detection timing sequences of the same detection mode to detect the sample to be tested; the processor is also configured to, when the detection component performs detection using different detection modes, superimpose the detection timing sequences of different detection modes to detect the sample to be tested. The overlapping segments of the detection timing sequence for the same detection mode are different from those for different detection modes.
2. The sample detection device according to claim 1, characterized in that, The sample introduction component is used to acquire a first test sample and a second test sample, as well as to acquire sample information of the first test sample and the second test sample; The processor is used to superimpose the detection timing under the detection mode when the sample information indicates that the detection mode of the first sample to be tested and the second sample to be tested is the same detection mode; The processor is further configured to, when the sample information indicates that the detection modes of the first test sample and the second test sample are different detection modes, superimpose the detection timing of the detection mode corresponding to the second test sample into the detection timing of the detection mode corresponding to the first test sample.
3. The sample detection device according to claim 2, characterized in that, The detection component includes at least a first detection mode and a second detection mode, and the processor stores a first timing sequence corresponding to the first detection mode and a second timing sequence corresponding to the second detection mode; The processor is configured to, when the sample information indicates that the detection mode of the first sample to be tested and the second sample to be tested is the first detection mode, call a first overlay segment in the first time sequence to detect the second sample to be tested, so that adjacent first time sequences are overlaid in the first overlay segment; The processor is further configured to, when the sample information indicates that the detection mode of the first sample to be tested is the first detection mode and the detection mode of the second sample to be tested is the second detection mode, call a second overlay segment in the first timing sequence to detect the second sample to be tested, so that the first timing sequence and the second timing sequence are overlaid in the second overlay segment; The positions of the first superimposed segment and the second superimposed segment in the first time sequence are different.
4. The sample detection device according to claim 3, characterized in that, The position of the first overlay segment in the first time sequence partially overlaps with the position of the second overlay segment in the first time sequence; and / or, The start time of the first overlay segment in the first time series is the first time, and the start time of the second overlay segment in the first time series is the second time, with the first time being earlier than the second time.
5. The sample detection device according to claim 3, characterized in that, The processor is configured to, when the sample information indicates that the detection mode of the first sample to be tested and the second sample to be tested is the second detection mode, call a third overlay segment in the second timing sequence to detect the second sample to be tested, so that adjacent second timing sequences are overlaid in the third overlay segment; The processor is further configured to, when the sample information indicates that the detection mode of the first sample to be tested is the second detection mode and the detection mode of the second sample to be tested is the first detection mode, call the fourth overlay segment in the second timing sequence to detect the second sample to be tested, so that the second timing sequence and the first timing sequence are overlaid in the fourth overlay segment; The third overlay segment and the fourth overlay segment are not in the same position in the second time series.
6. The sample detection device according to claim 5, characterized in that, The third and fourth overlay segments do not overlap in the second time sequence; and / or, The start time of the third overlay segment in the second time series is the third time, and the start time of the fourth overlay segment in the second time series is the fourth time. The third time is earlier than the fourth time.
7. The sample detection device according to claim 3, characterized in that, The detection component further includes a third detection mode, and the processor further stores a third timing sequence corresponding to the third detection mode; The processor is further configured to, when the sample information indicates that the detection mode of the first sample to be tested is the first detection mode and the detection mode of the second sample to be tested is the third detection mode, call the fifth overlay segment in the first timing sequence to detect the second sample to be tested, so that the first timing sequence and the third timing sequence are overlaid in the fifth overlay segment; The positions of the first superimposed segment, the second superimposed segment, and the fifth superimposed segment in the first time sequence are different.
8. The sample detection device according to claim 2, characterized in that, The sample introduction component includes a scanning mechanism, and the processor is connected to the scanning mechanism. The scanning mechanism is used to receive a first sample tube storing the first sample to be tested and a second sample tube storing the second sample to be tested. The scanning mechanism is also used to scan the first sample tube to obtain first sample information of the first sample to be tested, and to scan the second sample tube to obtain second sample information of the second sample to be tested. The processor is configured to control the detection timing under the detection mode to be superimposed at the first detection node when the detection modes indicated by the first sample information and the second sample information are the same; The processor is configured to control the detection timing of different detection modes to be superimposed at the second detection node when the detection modes indicated by the first sample information and the second sample information are different; The first detection node is earlier than the second detection node.
9. The sample detection device according to claim 8, characterized in that, The start time of the superposition segment of the first detection node is the fifth time, and the time when the scanning mechanism acquires the first sample information and the second sample information is the sixth time, which is earlier than the fifth time; And / or, The start time of the superposition segment of the second detection node is the seventh time, and the time when the scanning mechanism acquires the first sample information and the second sample information is the sixth time, which is earlier than the seventh time.
10. A sample detection method, characterized in that, include: Obtain the sample to be tested; When the detection components perform detection using the same detection mode, the detection timing of the same detection mode is superimposed to detect the sample to be tested; When the detection component performs detection through different detection modes, the detection timing of the different detection modes is superimposed to detect the sample to be tested; The overlapping segments of the detection timing sequence for the same detection mode are different from those for different detection modes.