Spiral electrode implantation device

Abstract

This invention relates to a spiral electrode implantation device, belonging to the fields of medical device technology or neuroscience research. The spiral electrode implantation device is placed on the wall of an intracranial blood vessel and includes a spiral support, electrode wires, and contrast agents. The spiral support has a spiral shape; the support body has spiral electrode wires; and contrast agents are located at both ends of the spiral support. This invention allows for electrode implantation via transvascular intervention to collect electrical signals; it has a simple structure and high achievability; the electrode adheres well to the blood vessel wall, resulting in excellent signal acquisition; its small cross-section allows for delivery through a thin sheath, reaching distal small blood vessels, meeting the requirements for electrode acquisition in deep brain locations and multi-point (brain region) electrode implantation within the intracranial cavity.

Description

Technical Field

[0001] This invention relates to a spiral electrode implantation device, belonging to the field of medical device technology or neuroscience research. Background Technology

[0002] In recent years, brain-computer interface (BCI) technology has developed rapidly. BCI refers to the creation of a connection between the brain and external devices, enabling information exchange between them. It is a revolutionary human-computer interaction technology that bypasses peripheral nerves and muscles, directly establishing a new communication and control channel between the brain and external devices. It captures and decodes brain signals to achieve information transmission, control, and even feedback regulation. Currently, EEG signal recording based on invasive intracranial electrodes has attracted significant attention in BCI technology. Recording EEG signals using intracranial electrodes allows for the acquisition of EEG signals with a wider frequency range and higher signal accuracy. Furthermore, the electrode design allows for multi-channel acquisition of local field potential signals from multiple neurons, as well as the acquisition of electrical activity from individual neurons, laying an important data foundation for BCI applications. However, current intracranial electrodes are implanted surgically, resulting in significant surgical trauma and making deep brain implantation difficult. Open craniotomy is a highly invasive procedure that carries significant risks, including intracranial hemorrhage and infection, limiting the wider application of invasive brain-computer interfaces. Therefore, this field urgently needs to address the technical challenges of developing minimally invasive, non-open craniotomy-compatible, highly safe intracranial electrodes that can be implanted deep within the brain or in multiple brain regions. Summary of the Invention

[0003] The purpose of this invention is to solve the technical problem of how to obtain an intracranial implantable electrode that does not require craniotomy, is highly safe, has low risk, can be implanted in deep brain regions, and can be implanted in multiple brain regions.

[0004] To address the aforementioned problems, the present invention provides a spiral electrode implantation device, which is disposed on the intracranial blood vessel wall and includes a spiral stent, electrode wires, and contrast agents. The body of the spiral stent is spiral-shaped, and the stent body is provided with spiral-shaped electrode wires. Contrast agents are provided at both ends of the spiral stent.

[0005] Preferably, the electrode wire is located on the radial outer side of the spiral support.

[0006] Preferably, the spiral support and the electrode wire are provided with developing and fixing rings at both ends.

[0007] Preferably, the structure of the developing fixing ring includes a circular tube, a rectangular tube, or a spring.

[0008] Preferably, the overall appearance of the spiral support body is a cylindrical spiral shape or a tapered spiral shape, and the taper of the tapered spiral shape is in the range of 5°-20°.

[0009] Preferably, the pitch of the spiral bracket is set to a fixed pitch, with a pitch range of 0.5-5mm.

[0010] Preferably, the pitch of the spiral support is set to a variable pitch, which includes the pitch at both ends of the support being smaller than the pitch in the middle section; or the pitch at the far end being smaller than the pitch at the near end; or the pitch being dynamically adjusted by releasing changes in tension.

[0011] Preferably, the material used to manufacture the spiral support body includes flat wire, round wire, C-shaped wire, or concave / convex wire.

[0012] Preferably, the material used to manufacture the spiral support body includes nickel-titanium alloy, cobalt-chromium alloy, stainless steel, or carbon nanotubes.

[0013] Compared with the prior art, the present invention has the following beneficial effects:

[0014] 1. The present invention allows for the implantation of electrodes via vascular intervention to collect electrical signals.

[0015] 2. The present invention has a simple structure and a high degree of feasibility; the electrode fits well with the blood vessel wall, and the electrode has excellent signal acquisition effect; the cross-section is small, and it can be delivered through a thin sheath, reaching the distal small blood vessels, meeting the requirements for electrode implantation in the terminal small blood vessels of the intracranial cavity and at multiple points. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the structure of the present invention. Figure 1 ;

[0017] Figure 2 This is a schematic diagram of the structure of the present invention. Figure 2 ;

[0018] Figure 3 This is a schematic diagram of the structure of the present invention. Figure 3 ;

[0019] Figure 4 This is a schematic diagram of the structure of the present invention. Figure 4 ;

[0020] Reference numerals: 1. Spiral support; 2. Electrode wire; 3. Development and fixation ring; Detailed Implementation

[0021] To make the present invention more apparent and understandable, preferred embodiments are described in detail below with reference to the accompanying drawings:

[0022] like Figure 1-4 As shown, this invention provides a spiral electrode implantation device, which is disposed on the intracranial blood vessel wall and includes a spiral stent 1, electrode wires 2, and a contrast agent. The body of the spiral stent 1 is spiral-shaped; the stent body is provided with spiral-shaped electrode wires 2; and contrast agents are provided at both ends of the spiral stent 1. The electrode wires 2 are located radially outward of the spiral stent 1. Contrast-fixing rings 3 are provided at both ends of the spiral stent 1 and the electrode wires 2. The structure of the contrast-fixing rings 3 includes a cylindrical tube, a rectangular tube, or a spring. The overall appearance of the spiral stent 1 is a cylindrical spiral shape or a tapered spiral shape, and the taper ranges from 5° to 20°. The pitch of the spiral stent 1 is set to a fixed pitch, with a pitch range of 0.5-5 mm; or, the pitch of the spiral stent is set to a variable pitch, wherein the pitch at both ends of the stent is smaller than the pitch in the middle section; or the pitch at the distal end is smaller than the pitch at the proximal end.

[0023] The materials used to manufacture the spiral support body include flat wire, round wire, C-shaped wire, or concave / convex wire.

[0024] The materials used to manufacture the spiral support body include nickel-titanium alloy, cobalt-chromium alloy, stainless steel, or carbon nanotubes.

[0025] Example

[0026] like Figure 1-4 As shown, the present invention provides a spiral electrode implantation device, which is implanted on the wall of an intracranial blood vessel; the spiral electrode implantation device is implanted on the wall of an intracranial blood vessel via vascular intervention to collect electrical signals.

[0027] The electrode device on the intracranial blood vessel wall includes a spiral stent 1, electrode wires 2, and contrast material;

[0028] In this embodiment, the body of the spiral stent 1 is formed into a spiral shape by processing a thin, flat filament with a "U"-shaped cross-section (filament width 0.1-0.5mm, thickness-to-width ratio 1:5-1:2). The concave surface of the "U" shape is set on the outer side of the stent, that is, the outer arc surface of the spiral shape. An electrode wire 2 is embedded in the groove of the concave surface and is located on the radial outer side of the spiral stent 1. The electrode wire 2 is fixed in the groove, making the outer surface of the stent more flat. The electrode wire 2 also becomes spiral-shaped as the body of the spiral stent 1 rotates. The electrode wire 2 is attached to the spiral stent 1 and arranged on the radial outer side of the spiral stent 1. The spiral stent 1 can press the electrode wire 2 to adhere to the blood vessel wall.

[0029] Two ends of the spiral stent 1 are provided with radiopaque members. In this embodiment, two ends of the spiral stent 1 and the electrode wire 2 are provided with radiopaque fixing rings 3. The structure of the radiopaque fixing ring 3 includes a round tubular shape, a rectangular tubular shape or a spring shape.

[0030] The radiopaque fixing ring 3 is fixed to the spiral stent 1 and the electrode wire 2 by means of welding, bonding, mechanical clamping and the like, and has the functions of radiopacity and connection; the material of the radiopaque fixing ring 3 is platinum-iridium alloy or platinum-tungsten alloy.

[0031] In this embodiment, the overall shape of the main body of the spiral stent 1 is a cylindrical spiral shape;

[0032] In this embodiment, the pitch of the spiral stent 1 is set to a fixed pitch, and the pitch ranges from 0.5 mm to 5 mm; the material of the spiral stent is nickel-titanium alloy.

[0033] In another embodiment, the overall shape of the main body of the spiral stent 1 is a tapered spiral shape, and the taper ranges from 5° to 20°.

[0034] In another embodiment, the pitch of the spiral stent 1 can be set to a variable pitch, and the types of the variable pitch include a smaller pitch at both ends and a larger pitch in the middle; or a smaller pitch at the distal end and a larger pitch at the proximal end;

[0035] In other embodiments, the spiral stent can be formed by processing a flat wire (the width of the flat wire is 0.1-0.5 mm, and the ratio of thickness to width is 1:5-1:2), a round wire (the diameter of the round wire is 0.05-0.20 mm), a C-shaped wire (the width of the wire is 0.1-0.5 mm, and the ratio of thickness to width is 1:5-1:2), or a "convex"-shaped wire (the width of the wire is 0.1-0.5 mm, and the ratio of thickness to width is 1:5-1:2). The materials of the spiral stent include nickel-titanium alloy, cobalt-chromium alloy, stainless steel or carbon nanotubes.

[0036] In another embodiment, the spiral stent 1 is a rectangular spiral stent; the electrodes are connected to the outer surface of the stent, the number of the electrode wires can be one or more, and there can be a plurality of detection sites (that is, multi-channel signal communication is realized).

[0037] In another embodiment, the outer side surface of the spiral stent 1 is provided with a barb structure, which is used to fix the spiral stent 1 on the blood vessel wall.

[0038] In another embodiment, the end face of the spiral stent 1 at the end away from the operator is provided with a folded edge that is turned inward toward the center line of the spiral body, or a connecting narrow strip is radially arranged along the end face of the spiral stent 1 at the end away from the operator (both ends of the connecting narrow strip are connected to the stent main body on the distal end face of the spiral stent 1); the function of the folded edge and the narrow strip is that when the spiral stent 1 is sleeved on the end of the stent pushing guide wire, the folded edge and the narrow strip can abut against the end of the guide wire when the guide wire advances, so that the spiral stent 1 will not fall off.

[0039] In another embodiment, the end face of the helical stent 1 near the operator has a raised band protruding outward from the helical body, and the plane of the raised band is perpendicular to the center line of the helical body. The function of the raised band is that when the helical stent 1, which is fitted at the end of the stent pusher wire, reaches the target blood vessel wall, the microcatheter fitted outside the helical stent 1 retracts, exposing the helical stent 1 at the end of the stent pusher wire. Under the guidance of the contrast agent and the contrast fixing ring 3, the helical stent 1 is pressed against the blood vessel wall. The microcatheter continues to retract until the helical stent 1 is completely exposed. After the helical stent 1 is completely detached from the microcatheter, the outer diameter of the helical stent 1 expands freely due to the release from the microcatheter's restraint, and its outer diameter increases. The outer diameter of the helical stent 1 near the operator is also larger than the outer diameter of the microcatheter. The microcatheter pushes against the raised band at the end of the helical stent 1. At the same time, the stent pusher wire retracts, thereby causing the helical stent 1 to detach from the stent pusher wire and remain on the blood vessel wall.

[0040] The process of using this invention:

[0041] 1. Establish vascular access using arterial sheaths, support catheters, guidewires, and microcatheters.

[0042] 2. Select a suitable outer diameter spiral stent 1 based on the inner diameter of the target blood vessel. The outer diameter of the spiral stent 1 is equal to or slightly larger than the inner diameter of the target blood vessel.

[0043] 3. Place the spiral stent 1 onto the end of the stent pusher wire; the inner diameter of the spiral stent 1 can be slightly larger than the outer diameter of the stent pusher wire, and the outer diameter of the spiral stent 1 is equal to or slightly larger than the inner diameter of the microcatheter; (when the spiral stent 1 is pushed into the microcatheter by the stent pusher wire, since the outer diameter of the spiral stent 1 is equal to or slightly larger than the inner diameter of the microcatheter, the spiral stent 1 is stretched, the outer diameter becomes smaller, and it is thus inserted into the microcatheter and moves within the microcatheter).

[0044] 4. After the interventional pathway is constructed to the target location, the spiral stent 1 can be placed on the end of the stent pusher wire and inserted into the microcatheter, and then pushed forward by the stent pusher wire;

[0045] 5. When the spiral stent 1, which is attached to the end of the stent delivery guidewire, reaches the target blood vessel, the microcatheter attached to the spiral stent 1 is retracted to expose the spiral stent 1 at the end of the stent delivery guidewire. The microcatheter continues to retract until the spiral stent 1 is fully exposed (this process can be coordinated with the stent delivery guidewire). After the spiral stent 1 is completely detached from the microcatheter, its outer diameter expands freely due to the removal of the microcatheter's constraint, and its outer diameter increases, with the periphery of the spiral stent 1 abutting against the blood vessel wall. The outer diameter of the spiral stent 1 at the end closest to the operator is also larger than the outer diameter of the microcatheter, and the microcatheter pushes against the protruding band at the end of the spiral stent 1. At the same time, the stent delivery guidewire is retracted, thereby completely detaching the spiral stent 1 from the stent delivery guidewire and leaving it on the blood vessel wall.

[0046] 6. During the release process, the spiral stent 1 expands on its own, causing the electrode wire 2 to adhere to the blood vessel wall;

[0047] 7. Finally, bioelectrical signals (including electroencephalogram signals) are collected by flexible electrodes attached to the blood vessel wall through a stent. The signals can be collected using wireless flexible electrodes or wired electrodes.

[0048] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any form or substance. It should be noted that those skilled in the art can make various improvements and additions without departing from the present invention, and these improvements and additions should also be considered within the scope of protection of the present invention. Any modifications, alterations, and equivalent changes made by those skilled in the art based on the above-disclosed technical content without departing from the spirit and scope of the present invention are equivalent embodiments of the present invention. Furthermore, any modifications, alterations, and evolutions made to the above embodiments based on the essential technology of the present invention still fall within the scope of the technical solution of the present invention.

Claims

1. A spiral electrode implantation device, characterized in that, The spiral electrode implantation device is placed on the intracranial blood vessel wall and includes a spiral stent, electrode wires, and contrast agents; the body of the spiral stent is spiral-shaped; the stent body is provided with spiral-shaped electrode wires; and contrast agents are provided at both ends of the spiral stent.

2. The spiral electrode implantation device according to claim 1, characterized in that, The electrode wire is located on the radial outer side of the spiral support.

3. The spiral electrode implantation device according to claim 2, characterized in that, The spiral support and electrode wire are provided with developing and fixing rings at both ends.

4. The spiral electrode implantation device according to claim 3, characterized in that, The structure of the developing fixation ring includes a circular tube, a rectangular tube, or a spring.

5. The spiral electrode implantation device according to claim 1, characterized in that, The overall appearance of the spiral support is either a cylindrical spiral shape or a tapered spiral shape, with the taper ranging from 5° to 20°.

6. The spiral electrode implantation device according to claim 1, characterized in that, The pitch of the spiral bracket is set to a fixed pitch, with a pitch range of 0.5-5mm.

7. The spiral electrode implantation device according to claim 1, characterized in that, The pitch of the spiral support is set to a variable pitch, which includes the pitch at both ends of the support being smaller than the pitch in the middle section; or the pitch at the far end being smaller than the pitch at the near end.

8. The spiral electrode implantation device according to claim 1, characterized in that, The materials used to manufacture the spiral support body include flat wire, round wire, C-shaped wire, or concave / convex wire.

9. A spiral electrode implantation device according to claim 1, characterized in that, The materials used to manufacture the spiral support body include nickel-titanium alloy, cobalt-chromium alloy, stainless steel, or carbon nanotubes.

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