A traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain and a preparation method thereof

Abstract

This invention discloses a traditional Chinese medicine composition for treating neck, shoulder, lower back, and leg pain, and its preparation method. The composition comprises *Lycopodium clavatum*, *Spatholobus suberectus*, *Eucommia ulmoides*, *Panax notoginseng*, *Dracaena cochinchinensis*, *Drynaria fortunei*, and *Carthamus tinctorius*. The preparation method involves mixing the raw materials, decocting them in water, and then sealing and soaking the resulting liquid and dregs in a container. The composition exhibits synergistic effects, promoting blood circulation, strengthening muscles and bones, reducing swelling, and relieving pain. It also has detoxifying properties, facilitating the excretion of inflammatory edema exudates accumulated in local soft tissues through the skin. The decoction followed by soaking method ensures thorough extraction of the active ingredients. This composition can be formulated as a topical application solution, characterized by good transdermal absorption, rapid onset of action, thorough detoxification, long-lasting efficacy, and safe and convenient use. It is suitable for treating cervical spondylosis, frozen shoulder, lumbar disc herniation, lumbar muscle strain, sprains, and strains.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine technology, specifically to a traditional Chinese medicine composition for treating neck, shoulder, back and leg pain and its preparation method. Background Technology

[0002] Neck, shoulder, lower back, and leg pain are common and frequently occurring clinical conditions, primarily including pain symptoms caused by cervical spondylosis, frozen shoulder, lumbar disc herniation, and lumbar muscle strain. These conditions severely impact patients' daily lives and work abilities, causing significant physical and psychological suffering.

[0003] Currently, clinical treatments for neck, shoulder, lower back, and leg pain mainly include medication, physical therapy, and surgery. Medication primarily involves oral nonsteroidal anti-inflammatory drugs (NSAIDs) and traditional Chinese medicine. However, oral medications have limitations. Firstly, long-term use of NSAIDs can easily cause systemic side effects such as gastrointestinal irritation and liver and kidney toxicity. Secondly, oral traditional Chinese medicine requires absorption through the digestive tract, resulting in a relatively slow onset of action and the presence of a first-pass effect in the liver, affecting efficacy. While topical plasters and patches allow for localized drug delivery, they often suffer from low transdermal absorption rates, slow onset of action, and the need for prolonged application, which can cause skin discomfort. Furthermore, some plaster formulations have complex manufacturing processes and high costs.

[0004] Therefore, developing a simple, easily absorbed, rapidly effective, and safe traditional Chinese medicine external preparation is of great clinical significance for the treatment of neck, shoulder, back and leg pain. Summary of the Invention

[0005] In view of this, the present invention provides a traditional Chinese medicine composition for treating neck, shoulder, back and leg pain and its preparation method. The traditional Chinese medicine composition has good transdermal absorption, rapid onset of action, and safe use. It can also actively promote the excretion of toxins such as local soft tissue edema and inflammatory exudates through the skin, thereby relieving nerve compression and providing long-lasting therapeutic effects.

[0006] The technical solution provided by this invention is as follows: In a first aspect, the present invention provides a traditional Chinese medicine composition for treating neck, shoulder, back and leg pain, the active ingredients of which are made from the following raw materials: The ingredients include: *Shenjincao* (a type of herb), *Jixueteng* (a type of herb), *Duzhong* (a type of herb), *Sanqi* (a type of herb), *Xuejie* (a type of herb), *Gusuibu* (a type of herb), and *Honghua* (a type of herb).

[0007] Furthermore, its active ingredient is made from the following raw materials in parts by weight: One part of *Shenjincao* (a type of herb), one part of *Jixueteng* (a type of herb), one part of *Duzhong* (another type of herb), one part of *Sanqi* (a type of herb), one part of *Xuejie* (a type of herb), one part of *Gusuibu* (a type of herb), and one part of *Honghua* (a type of herb).

[0008] Secondly, the present invention provides a method for preparing a traditional Chinese medicine composition for treating neck, shoulder, back and leg pain as described in any of the preceding claims, comprising the following steps: Weigh out common clubmoss herb, suberect spatholobus stem, eucommia bark, notoginseng, dragon's blood, fortune's drynaria rhizome and safflower according to the ratio, add water for decoction, after decoction is completed, place the obtained medicinal liquid and medicinal dregs together in a container, seal and soak, to obtain the product.

[0009] Further, the amount of water added during decoction is 6 to 10 times the total weight of the raw medicinal materials.

[0010] Further, the time for the sealed soaking is 1 month.

[0011] In a third aspect, the present invention provides a traditional Chinese medicine preparation for treating neck, shoulder, waist and leg pain, comprising the traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain described in any one of the above items.

[0012] In a fourth aspect, the present invention provides the use of the traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain described in any one of the above items in the preparation of an external medicament for treating neck, shoulder, waist and leg pain.

[0013] Further, the neck, shoulder, waist and leg pain includes cervical spondylosis, periarthritis of shoulder, lumbar disc herniation, lumbar muscle strain, traumatic injury and sprain.

[0014] The components of the traditional Chinese medicine composition for use in the present invention and their main efficacies are as follows: Common clubmoss herb: slightly bitter and pungent in flavor, warm in nature, acting on the liver, spleen and kidney meridians, it has the efficacy of relaxing tendons and activating collaterals, and is mainly indicated for rheumatic arthralgia, joint flexion and extension disadvantage, and traumatic injury.

[0015] Suberect spatholobus stem: bitter and sweet in flavor, warm in nature, acting on the liver and kidney meridians, it has the efficacies of activating blood and enriching blood, and relaxing tendons and activating collaterals, and is mainly indicated for rheumatic arthralgia, limb numbness, and blood deficiency with sallow complexion.

[0016] Eucommia bark: sweet in flavor, warm in nature, acting on the liver and kidney meridians, it has the efficacies of tonifying the liver and kidney, and strengthening the bones and tendons, and is mainly indicated for soreness and pain in the waist and knees, weakness of bones and tendons, and liver-kidney insufficiency.

[0017] Notoginseng: sweet and slightly bitter in flavor, warm in nature, acting on the liver and stomach meridians, it has the efficacies of dissipating stasis and arresting bleeding, and alleviating swelling and pain, and is mainly indicated for traumatic injury, swelling and pain due to static blood, and internal and external bleeding.

[0018] Dragon's blood: sweet and salty in flavor, neutral in nature, acting on the heart and liver meridians, it has the efficacies of activating blood and alleviating pain, removing stasis and arresting bleeding, and promoting tissue regeneration and healing sore, and is mainly indicated for traumatic injury, swelling and pain due to static blood, and traumatic bleeding.

[0019] Fortune's drynaria rhizome: bitter in flavor, warm in nature, acting on the liver and kidney meridians, it has the efficacies of tonifying the kidney and strengthening bones, and healing injury and alleviating pain, and is mainly indicated for traumatic injury, fracture of bones and tendons, and soreness and pain in the waist and knees.

[0020] Safflower: pungent in flavor, warm in nature, acting on the heart and liver meridians, it has the efficacies of activating blood and regulating menstruation, and dissipating stasis and alleviating pain, and is mainly indicated for traumatic injury, swelling and pain due to static blood, amenorrhea, and dysmenorrhea.

[0021] In the full combined prescription, common clubmoss herb relaxes the tendons and activates the collaterals, suberect spatholobus stem invigorates blood circulation, nourishes blood, and moistens and nourishes the tendons and vessels, and eucommia bark tonifies the liver and kidney, and nourishes the tendons and bones. These three serve as the sovereign drugs of the prescription, jointly exerting the effects of tonifying the liver and kidney and nourishing the tendons and vessels; notoginseng, dragon's blood, and safflower invigorate blood circulation to resolve stasis, reduce swelling and alleviate pain, and together serve as ministerial drugs, assisting the sovereign drugs to enhance the effects of unblocking the collaterals, dissipating static swelling, and quickly relieving pain. Fortune's drynaria rhizome acts as the adjuvant drug, which can not only assist eucommia bark in tonifying the liver and kidney and strengthening the tendons and bones, but also cooperate with the blood-invigorating drugs to reconnect the tendons and bones and relieve injury pain. The combined compatibility and synergy of all the drugs jointly exert the effects of relaxing tendons and activating collaterals, invigorating blood circulation and resolving stasis, strengthening tendons and bones, and reducing swelling and relieving pain.

[0022] The beneficial effects of the present invention are as follows: 1. In the prescription of the present invention, common clubmoss herb relaxes the tendons and activates the collaterals, suberect spatholobus stem invigorates blood circulation, nourishes blood, and moistens and nourishes the tendons and vessels, and eucommia bark tonifies the liver and kidney and nourishes the tendons and bones. These three drugs together serve as the sovereign drugs, focusing on tonifying the liver and kidney and nourishing the tendons and vessels to address the root cause; notoginseng, dragon's blood, and safflower invigorate blood circulation to resolve stasis, reduce swelling and alleviate pain, and together serve as ministerial drugs, assisting the sovereign drugs to unblock collaterals and dissipate stasis, and relieve acute pain; fortune's drynaria rhizome acts as the adjuvant drug, assisting eucommia bark to strengthen the tendons and bones, and cooperating with the blood-invigorating drugs to reconnect injured tendons. The combined use of all drugs jointly exerts the effects of relaxing tendons and activating collaterals, resolving stasis and strengthening bones, and reducing swelling and relieving pain, and exerts a synergistic therapeutic effect targeting the etiology and pathogenesis of neck, shoulder, waist and leg pain.

[0023] 2. The present invention adopts a preparation method of decocting first and then soaking. The active ingredients in the medicinal materials are preliminarily dissolved out through decoction, and then the remaining active ingredients as well as volatile and fat-soluble ingredients in the medicinal residues are further fully dissolved out into the medicinal liquid through long-term sealed soaking. Compared with simple decoction or simple soaking, the extraction of active ingredients is more sufficient, and the utilization rate of medicinal materials is high.

[0024] 3. The present invention is an externally applied medicinal liquid for smearing and rubbing. When in use, it is directly applied to the pain site of the patient, and is combined with manual massage to promote the penetration of the medicinal liquid into skin tissues, so that the drug can directly reach the lesion site and take effect quickly. Compared with oral drugs, it avoids the hepatic first-pass effect and gastrointestinal irritation, and has high safety.

[0025] 4. The medicinal liquid of the present invention has a remarkable effect of expelling toxins. After external smearing and rubbing, it can actively promote the accumulated inflammatory edema exudate and stagnant pathological products in local soft tissues to be discharged outwards through the skin, and secretions can be seen on the skin of the affected area clinically, thereby effectively relieving symptoms such as pain and numbness caused by tissue edema compressing nerves. For ordinary patients, the toxin expelling process lasts for about a week; for intractable cases such as lumbar disc herniation with long course of disease and severe condition, the toxin expelling time can last for more than ten days until the pathological products are basically completely discharged, and the pain is fundamentally relieved, with lasting curative effect and low recurrence tendency. Detailed Description of the Embodiments

[0026] To make the objectives, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of them. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative work shall fall within the protection scope of the present invention. For the experimental methods without specific conditions indicated in the following examples, the methods are usually carried out according to conventional conditions or according to the conditions suggested by the manufacturer. Unless otherwise specified, percentages and parts are percentages by weight and parts by weight.

[0027] Unless otherwise defined, the technical and scientific terms used herein have the same meanings as commonly understood by one of ordinary skill in the technical field to which this application belongs. It should be noted that the terms used herein are only for describing specific embodiments, and are not intended to limit the exemplary embodiments of the present application.

[0028] Example 1 A traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, the active ingredients of which are made from the following raw materials: 100g of Common Clubmoss Herb, 100g of Suberect Spatholobus Stem, 100g of Eucommia Bark, 100g of Panax Notoginseng, 100g of Dragon's Blood, 100g of Fortune's Drynaria Rhizome, and 100g of Safflower.

[0029] A preparation method of the traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain comprises the following steps: Take 100g each of Common Clubmoss Herb, Suberect Spatholobus Stem, Eucommia Bark, Panax Notoginseng, Dragon's Blood, Fortune's Drynaria Rhizome and Safflower, mix them and place the mixture in a decoction container, add 8 times the amount of water, and decoct at 80°C for 1 hour; after the decoction is completed, transfer the obtained medicinal liquid and medicinal dregs together to a sealed container, and perform sealed soaking at room temperature for 1 month to obtain the product.

[0030] Usage: Take an appropriate amount of the medicinal liquid and apply it to the painful part of the patient, and perform manual massage for 45 to 60 minutes at the same time to make the medicinal liquid fully penetrate into the skin tissue, and replace it every 24 hours. After medication, a small amount of exudate can be seen discharged from the local skin of some patients, which is a normal detoxification reaction and no special treatment is required; generally, the detoxification process lasts for about a week, and for patients with severe conditions, it can last for more than ten days. When the secretion decreases or disappears, the pain and nerve compression symptoms will be significantly improved.

[0031] Example 2 A traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, the active ingredients of which are made from the following raw materials: 50g of Common Clubmoss Herb, 50g of Suberect Spatholobus Stem, 50g of Eucommia Bark, 50g of Panax Notoginseng, 50g of Dragon's Blood, 50g of Fortune's Drynaria Rhizome, and 50g of Safflower.

[0032] A preparation method of the traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain comprises the following steps: Take 50g each of *Shenjincao*, *Jixueteng*, *Duzhong*, *Sanqi*, *Xuejie*, *Gusuibu*, ​​and *Honghua*, mix them together, place them in a decoction container, add 6 times the amount of water, and decoct at 75℃ for 2 hours. After decoction, transfer the resulting liquid and dregs to a sealed container and soak at room temperature for 1 month.

[0033] The usage method is the same as in Example 1.

[0034] Example 3 A traditional Chinese medicine composition for treating neck, shoulder, lower back, and leg pain, the active ingredients of which are made from the following raw materials: 200g of *Shenjincao* (a type of herb), 200g of *Jixueteng* (a type of herb), 200g of *Duzhong* (another type of herb), 200g of *Sanqi* (a type of herb), 200g of *Xuejie* (a type of herb), 200g of *Gusuibu* (a type of herb), and 200g of *Honghua* (a type of

[0035] A method for preparing a traditional Chinese medicine composition for treating neck, shoulder, lower back, and leg pain includes the following steps: Take 200g each of *Shenjincao*, *Jixueteng*, *Duzhong*, *Sanqi*, *Xuejie*, *Gusuibu*, ​​and *Honghua*, mix them together, place them in a decoction container, add 10 times the amount of water, and decoct at 85℃ for 1.5 hours. After decoction, transfer the resulting liquid and dregs to a sealed container and soak at room temperature for 1 month to obtain the final product.

[0036] The usage method is the same as in Example 1.

[0037] Typical Case Case 1: Mr. Zhang, male, 52 years old, suffered from persistent lower back pain due to long-term heavy physical labor. The pain worsened after exertion and was relieved by rest, accompanied by soreness and swelling in both lower limbs. The course of the illness was approximately 2 years. He had previously taken various oral analgesics and used topical ointments, but with little effect. He applied the medicinal solution prepared in Example 1 of this invention to the painful area of ​​his lower back, combined with manual massage, changing the medication every 24 hours. On the second day of application, a small amount of pale yellow exudate was discharged from the affected area of ​​his lower back, which is a detoxification reaction. After one week of use, the lower back pain was significantly reduced, the soreness and swelling in both lower limbs were relieved, and the exudate gradually decreased. After three weeks of use, the lower back pain had basically disappeared, there was no discomfort in both lower limbs, and the local exudate stopped. He continued to use it for another week to consolidate the therapeutic effect, and there was no recurrence during a 3-month follow-up.

[0038] Case 2: Ms. Li, 45 years old, experienced neck stiffness and pain, accompanied by a feeling of heaviness in both shoulders, limited mobility, and occasional dizziness due to prolonged desk work. The condition had persisted for approximately one year. She had previously undergone acupuncture and massage treatments, but the symptoms recurred. The medicinal solution prepared in Example 1 of this invention was applied to the painful areas of the neck and shoulders, combined with manual massage. The medication was changed every 24 hours. After 3 days of use, a small amount of discharge appeared on the skin of the neck and shoulders, and the pain was relieved. After another 3 days, the neck stiffness was significantly relieved, and the feeling of heaviness in the shoulders was reduced. After 2 weeks of use, the neck and shoulder pain had essentially disappeared, mobility was restored, dizziness disappeared, and the discharge ceased. No recurrence was observed during a 2-month follow-up.

[0039] Case 3: Mr. Wang, male, 38 years old, suffered a left knee sprain due to improper exercise, resulting in local swelling, pain, and limited mobility, with a course of illness of 3 days. He had previously used Yunnan Baiyao aerosol externally, but the effect was not obvious. The medicinal solution prepared in Example 1 of this invention was applied to the swollen and painful area of ​​the left knee joint, combined with manual massage, and the medication was changed every 24 hours. After one day of application, exudate began to drain from the local swelling area, and the swelling subsided accordingly. After two days of use, the swelling significantly decreased, and the pain lessened. After five days of use, the swelling had essentially disappeared, the pain had disappeared, knee joint mobility returned to normal, and the exudation stopped. No recurrence was observed during a one-month follow-up.

[0040] The above descriptions are merely embodiments of the present invention, and common knowledge such as specific technical solutions and / or characteristics are not described in detail here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the technical solutions of the present invention, and these should also be considered within the scope of protection of the present invention. These modifications and improvements will not affect the effectiveness of the implementation of the present invention or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A traditional Chinese medicine composition for treating neck, shoulder, lower back, and leg pain, characterized in that, Its active ingredients are made from the following raw materials: The ingredients include: *Shenjincao* (a type of herb), *Jixueteng* (a type of herb), *Duzhong* (a type of herb), *Sanqi* (a type of herb), *Xuejie* (a type of herb), *Gusuibu* (a type of herb), and *Honghua* (a type of herb).

2. The traditional Chinese medicine composition for treating neck, shoulder, back and leg pain according to claim 1, characterized in that, Its active ingredient is made from the following raw materials in parts by weight: One part of *Shenjincao* (a type of herb), one part of *Jixueteng* (a type of herb), one part of *Duzhong* (another type of herb), one part of *Sanqi* (a type of herb), one part of *Xuejie* (a type of herb), one part of *Gusuibu* (a type of herb), and one part of *Honghua* (a type of herb).

3. A method for preparing a traditional Chinese medicine composition for treating neck, shoulder, back, and leg pain as described in claim 1 or 2, characterized in that, Includes the following steps: Weigh out the following herbs according to the specified ratio: *Lycopodium clavatum*, *Spatholobus suberectus*, *Eucommia ulmoides*, *Panax notoginseng*, *Dracaena cochinchinensis*, *Drynaria fortunei*, and *Carthamus tinctorius*. Add water and decoct. After decoction, place the resulting liquid and dregs together in a container, seal and soak.

4. The method for preparing a traditional Chinese medicine composition for treating neck, shoulder, back and leg pain according to claim 3, characterized in that, The amount of water added during decoction is 6 to 10 times the total weight of the raw materials.

5. The method for preparing a traditional Chinese medicine composition for treating neck, shoulder, back and leg pain according to claim 3, characterized in that, The sealing and soaking time is 1 month.

6. A traditional Chinese medicine preparation for treating neck, shoulder, back, and leg pain, characterized in that, A traditional Chinese medicine composition for treating neck, shoulder, back and leg pain as described in claim 1 or 2.

7. The use of the traditional Chinese medicine composition for treating neck, shoulder, back and leg pain as described in claim 1 or 2 in the preparation of a topical medicine for treating neck, shoulder, back and leg pain.

8. The application according to claim 7, characterized in that, The neck, shoulder, back and leg pain mentioned includes cervical spondylosis, frozen shoulder, lumbar disc herniation, lumbar muscle strain, sprains and strains.