Multi-directional drug mixing methods, systems, terminals, and storage media
Patent Information
- Application Number
- CN202611433914.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-09-16
- Publication Date
- 2026-10-20
AI Technical Summary
[0004]针对上述中的相关技术,通过振动电机带着药品进行上下振动,然而药品类型不同的情况下,药液的性质不同,只通过上下振动会导致药液混合不均匀,还有改进的空间
1.通过对药品类型、药瓶材质和瓶底透光强度分析后确定药液性质参数,从而对药液粘度系数和药液性质参数分析后确定目标振动频率和目标振动幅度,对药液粘度系数、药液性质参数、目标振动频率和目标振动幅度分析后确定药品摇匀参数,从而根据药品摇匀参数控制药品摇匀装置对药瓶进行多方向摇匀,从而根据药液的性质来确定摇匀在水平方向和垂直方向的分量,从而有效避免因药液性质不同而导致混合不均匀的情况发生,进而保证提高药品摇匀时的均匀性的效果;
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Abstract
Description
Technical Field
[0001] This application relates to the technical field of drug mixing, and in particular to a drug mixing method, system, terminal and storage medium based on multi-directional mixing. Background Technology
[0002] The method of mixing medicines by shaking refers to the method of mixing the liquid in the medicine bottle evenly by using the mechanical movement of a medicine shaking device, with the aim of improving the uniformity of the medicine during shaking.
[0003] In related technologies, the drug mixing method usually involves placing the drug to be mixed into a clamping assembly, and then using a vibration motor to vibrate the drug up and down at a preset vibration frequency and amplitude, thereby fully mixing the drug solution with the solvent.
[0004] Regarding the aforementioned technologies, a vibration motor is used to vibrate the medicine up and down. However, different types of medicines have different properties, and simply vibrating up and down can lead to uneven mixing of the medicine. There is still room for improvement. Summary of the Invention
[0005] To ensure the effect of improving the uniformity of drug mixing, this application provides a drug mixing method, system, terminal, and storage medium based on multiple directions.
[0006] Firstly, this application provides a multi-directional drug mixing method, employing the following technical solution: Multi-directional drug mixing methods include: Obtain information such as drug type, bottle material, drug viscosity coefficient, and light transmittance at the bottom of the bottle; The drug type, bottle material, and light transmittance at the bottom of the bottle were analyzed to determine the property parameters of the drug solution. The viscosity coefficient and property parameters of the drug solution are analyzed to determine the target vibration frequency and target vibration amplitude. The viscosity coefficient, property parameters, target vibration frequency, and target vibration amplitude of the drug solution are analyzed to determine the parameters for drug mixing. The preset drug shaking device is controlled according to the drug shaking parameters to shake the preset medicine bottle in multiple directions.
[0007] Optionally, the steps of analyzing the drug type, bottle material, and light transmittance at the bottom of the bottle to determine the drug solution properties include: The vibration tolerance is determined based on the correspondence between the drug type and the preset vibration tolerance. The compressive strength coefficient of the medicine bottle is determined based on the correspondence between the material of the medicine bottle and the preset compressive strength of the medicine bottle; Calculate the quotient of the light transmittance intensity at the bottom of the bottle and the preset benchmark light transmittance intensity to generate the light transmittance ratio at the bottom of the bottle; Calculate the difference between the preset baseline transmittance and the transmittance at the bottom of the bottle to determine the degree of drug precipitation; Correlate vibration tolerance, bottle pressure resistance coefficient, and drug sedimentation degree to generate drug property parameters.
[0008] Optionally, the steps of analyzing the viscosity coefficient and property parameters of the drug solution to determine the target vibration frequency and target vibration amplitude include: Determine the degree of sedimentation and vibration tolerance of the drug solution based on its property parameters; The degree of drug sedimentation, viscosity coefficient, and vibration tolerance of the drug solution were analyzed to determine the target vibration frequency. The degree of drug sedimentation, the target vibration frequency, and the viscosity coefficient of the drug solution are input into a preset comprehensive amplitude function for solution to generate the target vibration amplitude.
[0009] Optionally, the steps of analyzing the degree of drug sedimentation, the viscosity coefficient of the drug solution, and the vibration tolerance to determine the target vibration frequency include: The viscosity coefficient, sedimentation degree, and preset benchmark overflow constant of the drug solution were analyzed to determine the frequency influencing factor. Calculate the product of the frequency influence factor and the preset frequency gain coefficient to generate the frequency adjustment term; The sum of the frequency adjustment term and the preset reference starting frequency is calculated to generate the adjusted vibration frequency; Get the maximum frequency of the motor; Calculate the product of vibration tolerance and the maximum frequency of the motor to generate the maximum vibration frequency; The adjusted vibration frequencies and the maximum vibration frequencies are sorted to determine the minimum vibration frequency, and the minimum vibration frequency is defined as the target vibration frequency.
[0010] Optionally, the steps of analyzing the viscosity coefficient, property parameters, target vibration frequency, and target vibration amplitude of the drug solution to determine the drug mixing parameters include: Determine the degree of sedimentation of the medicine solution and the pressure resistance coefficient of the medicine bottle based on the property parameters of the medicine solution; Calculate the quotient of the viscosity coefficient of the drug solution and the degree of sedimentation of the drug solution to generate the directional amplitude ratio; Determine whether the direction amplitude ratio is less than the preset reference amplitude ratio; If it is less than 1, the ratio of the target vibration amplitude to the directional amplitude is input into the preset vertical equation set for solution to determine the directional amplitude parameter. If it is not less than, the ratio of the target vibration amplitude to the directional amplitude is input into the preset horizontal equation set for solving to determine the directional amplitude parameter; The compressive strength coefficient of the medicine bottle, the target vibration frequency, and the target vibration amplitude are analyzed to determine the final clamping force; The associated directional amplitude parameters, target vibration frequency, and final clamping force are used to generate drug mixing parameters.
[0011] Optionally, the steps of analyzing the bottle's compressive strength, target vibration frequency, and target vibration amplitude to determine the final clamping force include: The target vibration frequency and amplitude are analyzed to determine the inertial acceleration; Obtain the quality of the medicine bottle; The mass and inertial acceleration of the medicine bottle were analyzed to determine the theoretical clamping force; Calculate the product of the pressure resistance coefficient of the medicine bottle and the preset maximum clamping force of the motor to generate the maximum force on the medicine bottle; The theoretical clamping force and the maximum force on the medicine bottle are ranked to determine the minimum clamping force, and the minimum clamping force is defined as the final clamping force.
[0012] Optionally, the steps of analyzing the bottle's mass and inertial acceleration to determine the theoretical clamping force include: Calculate the sum of inertial acceleration and preset gravitational acceleration to generate resultant acceleration; Calculate the product of the resultant acceleration and the mass of the medicine bottle to generate the maximum effective resultant force; Calculate the quotient of the maximum effective resultant force and the preset friction coefficient of the medicine bottle to generate the initial clamping force; Calculate the product of the initial clamping force and the preset safety factor for liquid sloshing to generate the theoretical clamping force.
[0013] Secondly, this application provides a multi-directional drug mixing system, employing the following technical solution: A multi-directional drug mixing system includes: The acquisition module is used to acquire information such as drug type, bottle material, drug viscosity coefficient, and light transmittance at the bottom of the bottle. A memory for storing a program for a multi-directional drug mixing method as described in any of the preceding claims; The processor and the program in the memory can be loaded and executed by the processor to implement the multi-directional drug shaking method as described in any of the above.
[0014] Thirdly, this application provides a smart terminal, which adopts the following technical solution: A smart terminal includes a memory and a processor, wherein the memory stores a computer program that can be loaded by the processor and executed as described in any of the preceding claims, based on a multi-directional drug shaking method.
[0015] Fourthly, this application provides a computer storage medium capable of storing corresponding programs, which facilitates the achievement of ensuring and improving the uniformity of drugs during shaking, and adopts the following technical solution: A computer-readable storage medium storing a computer program that can be loaded by a processor and executed by any of the above-described multidirectional drug shaking methods.
[0016] In summary, this application includes at least one of the following beneficial technical effects: 1. By analyzing the drug type, bottle material, and light transmittance at the bottom of the bottle, the property parameters of the drug solution are determined. Then, by analyzing the viscosity coefficient and property parameters of the drug solution, the target vibration frequency and amplitude are determined. Finally, by analyzing the viscosity coefficient, property parameters, target vibration frequency, and target vibration amplitude, the drug shaking parameters are determined. Based on these shaking parameters, the drug shaking device is controlled to shake the bottle in multiple directions. The horizontal and vertical components of the shaking are determined according to the properties of the drug solution, effectively avoiding uneven mixing due to different drug properties, thus ensuring improved uniformity during drug shaking. 2. Vibration tolerance is determined based on the relationship between drug type and vibration tolerance. The pressure resistance coefficient of the medicine bottle is determined based on the relationship between the bottle material and the pressure resistance of the medicine bottle. The light transmittance ratio of the bottle bottom is determined by calculating the quotient of the light transmittance intensity at the bottom of the bottle and the reference light transmittance intensity. The difference between the reference light transmittance ratio and the light transmittance ratio at the bottom of the bottle is then calculated to generate the degree of drug sedimentation. By associating vibration tolerance, pressure resistance coefficient of the medicine bottle, and degree of drug sedimentation, drug property parameters are generated, thereby determining the properties of the drug in the medicine bottle. This facilitates the subsequent determination of the target vibration frequency, target vibration amplitude, and drug shaking parameters. 3. After analyzing the degree of drug sedimentation, viscosity coefficient, and vibration tolerance, the target vibration frequency is determined. Then, the degree of drug sedimentation, target vibration frequency, and viscosity coefficient are input into the comprehensive amplitude function to obtain the target vibration amplitude. This determines the number of vibrations per unit time when the drug is shaken. At the same time, different vibration emphasis directions are selected according to the ratio of target vibration amplitude to directional amplitude and different drug properties, thereby ensuring the effect of improving the uniformity of the drug when shaken. Attached Figure Description
[0017] Figure 1 This is a flowchart of a multi-directional drug shaking method in the embodiments of this application.
[0018] Figure 2 This is a flowchart of the steps in this application embodiment to analyze the drug type, bottle material, and light transmittance at the bottom of the bottle to determine the property parameters of the drug solution.
[0019] Figure 3 This is a flowchart of the steps in this application embodiment to analyze the viscosity coefficient and property parameters of the drug solution to determine the target vibration frequency and target vibration amplitude.
[0020] Figure 4This is a flowchart of the steps in this application embodiment to analyze the degree of drug precipitation, drug viscosity coefficient and vibration tolerance to determine the target vibration frequency.
[0021] Figure 5 This is a flowchart of the steps in this application embodiment to analyze the viscosity coefficient of the drug solution, the property parameters of the drug solution, the target vibration frequency, and the target vibration amplitude to determine the drug shaking parameters.
[0022] Figure 6 This is a flowchart illustrating the steps in this application to analyze the pressure resistance coefficient of the medicine bottle, the target vibration frequency, and the target vibration amplitude to determine the final clamping force.
[0023] Figure 7 This is a flowchart illustrating the steps in this application embodiment to analyze the mass and inertial acceleration of the medicine bottle to determine the theoretical clamping force. Detailed Implementation
[0024] To make the purpose, technical solution, and advantages of this application clearer, the following description is provided in conjunction with the appendix. Figures 1 to 7 The present application will be further described in detail below with reference to embodiments. It should be understood that the specific embodiments described herein are for illustrative purposes only and are not intended to limit the scope of the application.
[0025] This application discloses a multi-directional drug shaking method, specifically a drug shaking device and a processing terminal. The processing terminal and the drug shaking device are communicatively connected to achieve data interaction and control. After the processing terminal acquires the drug type, bottle material, drug viscosity coefficient, and light transmittance at the bottom of the bottle, it analyzes the drug type, bottle material, and light transmittance to determine the drug property parameters. Then, it analyzes the drug viscosity coefficient and drug property parameters to determine the target vibration frequency and target vibration amplitude. Finally, it analyzes the drug viscosity coefficient, drug property parameters, target vibration frequency, and target vibration amplitude to determine the drug shaking parameters. Based on the drug shaking parameters, the drug shaking device is controlled to shake the bottle in multiple directions. The horizontal and vertical components of the shaking are determined according to the properties of the drug, thereby effectively avoiding uneven mixing due to different drug properties and ensuring improved uniformity during drug shaking.
[0026] Reference Figure 1 This application discloses a multi-directional drug mixing method, including the following steps: Step S100: Obtain the drug type, bottle material, drug viscosity coefficient, and light transmittance at the bottom of the bottle.
[0027] The drug type refers to the type of drug to be shaken, which is determined by the operator from the drug's instructions. Drug type is strongly correlated with vibration tolerance. For example, when the drug is a protein-based drug, it is highly susceptible to demulsification or inactivation, resulting in lower vibration tolerance. This provides data support for subsequent determination of vibration tolerance.
[0028] The material of a medicine bottle refers to the material of the container used to package the liquid medicine, which is determined by the operator from the instructions on the medicine packaging. The material of the medicine bottle is strongly related to its compressive strength. For example, when the medicine bottle is made of glass, it can withstand less force and is very easy to break, resulting in a lower compressive strength. This provides data support for subsequently determining the compressive strength of the medicine bottle.
[0029] The viscosity coefficient of a drug solution refers to the physical quantity that hinders the relative flow of the drug solution within the liquid. It is obtained by the operator from the drug parameters provided by the drug manufacturer. A higher viscosity coefficient indicates greater viscous resistance within the solution. In this case, if only up-and-down vibration is performed, it is more difficult for relative displacement to occur within the liquid, thus reducing the mixing effect. This provides data support for subsequently determining the mixing parameters.
[0030] The light transmittance at the bottom of the bottle refers to the value that measures the degree of light transmission at the bottom of the medicine bottle, which is measured in advance by the operator using a photoelectric sensor. The light transmittance at the bottom of the bottle is strongly correlated with the degree of sedimentation in the medicine solution. The lower the light transmittance at the bottom of the bottle, the more sediment is present at the bottom of the bottle, and thus the greater the degree of sedimentation in the medicine solution, which provides data support for subsequent determination of the degree of sedimentation in the medicine solution.
[0031] Step S101: Analyze the type of medicine, the material of the medicine bottle, and the light transmittance of the bottom of the bottle to determine the property parameters of the medicine solution.
[0032] Among them, the drug solution property parameters refer to the relevant physical properties of the drug solution in the shaken drug, including vibration tolerance, drug solution compressive strength coefficient, and drug solution sedimentation degree. These parameters are obtained by the processing terminal after analyzing the drug type, bottle material, and light transmittance at the bottom of the bottle. The specific method is described in [reference needed]. Figure 2 The steps involve determining the properties of the liquid in the vial by defining the parameters of the liquid's properties, which then facilitates the subsequent determination of the target vibration frequency, target vibration amplitude, and parameters for mixing the medicine.
[0033] Step S102: Analyze the viscosity coefficient and property parameters of the drug solution to determine the target vibration frequency and target vibration amplitude.
[0034] The target vibration frequency refers to the number of vibrations per unit time when the medicine is shaken, which is obtained by analyzing the viscosity coefficient and property parameters of the medicine solution at the processing terminal. The specific method is described in [reference needed]. Figure 3The steps involve determining the target vibration frequency to determine the number of vibrations per unit time during shaking, which facilitates the subsequent determination of shaking parameters.
[0035] The target vibration amplitude refers to the total distance that needs to be moved in space per unit time. It is obtained by analyzing the viscosity coefficient and property parameters of the drug solution at the processing terminal. For specific methods, please refer to [reference needed]. Figure 3 The steps are as follows: By determining the target vibration amplitude, the total distance moved in space per unit time is determined, so that the directional amplitude parameters can be determined according to the directional amplitude ratio. This allows for the selection of different vibration emphasis directions based on different drug properties, thereby ensuring the effect of improving the uniformity of the drug during shaking.
[0036] Step S103: Analyze the viscosity coefficient, property parameters, target vibration frequency, and target vibration amplitude of the drug solution to determine the drug mixing parameters.
[0037] Among them, the drug shaking parameters refer to the relevant control parameters during drug shaking, including directional amplitude parameters, target vibration frequency, and final clamping force. These parameters are obtained by the processing terminal after analyzing the drug solution viscosity coefficient, drug solution property parameters, target vibration frequency, and target vibration amplitude. Specific methods are described in [reference needed]. Figure 5 The steps are as follows. By determining the drug shaking parameters, the control parameters of the drug shaking device during drug shaking are determined, thereby effectively avoiding uneven mixing caused by different drug properties, and thus ensuring the effect of improving the uniformity of drug shaking.
[0038] Step S104: Control the preset medicine shaking device to shake the preset medicine bottle in multiple directions according to the medicine shaking parameters.
[0039] In this process, after determining the drug shaking parameters, the processing terminal controls the drug shaking device to shake the medicine bottle in multiple directions according to the drug shaking parameters. This allows for the determination of the optimal control parameters based on different drug types and bottle materials, ensuring that the drugs are mixed evenly without damaging the bottles, thereby improving the uniformity of drug shaking.
[0040] A drug shaking device is a device used to shake drugs evenly. The drug shaking device includes a base, a vibration motor, a cam mechanism, and a clamping assembly. The base serves as the foundation of the drug shaking device, and several vibration motors are installed on the base to provide vibration mechanical energy to the drug shaking device. The clamping assembly is installed on the cam mechanism and is used to fix the medicine bottle. After the vibration motors and the cam mechanism are linked, they drive the medicine bottle to vibrate in multiple directions, thereby improving the uniformity of the drug during shaking.
[0041] The medicine bottle refers to the medicine to be shaken well; the specific size is determined by the operator based on the actual situation.
[0042] Reference Figure 2 The steps for determining the properties of the drug solution by analyzing the type of drug, the material of the medicine bottle, and the light transmittance at the bottom of the bottle include: Step S200: Determine the vibration tolerance based on the drug type and the preset vibration tolerance correspondence.
[0043] The vibration tolerance correspondence refers to the relationship between drug type and vibration tolerance. For example, when the drug type is a protein drug, the drug is very easy to demulsify or become inactive. At this time, the drug has a low vibration tolerance, so the corresponding vibration tolerance is 0.8. When the drug type is a high-precipitation and high-viscosity liquid, the drug requires a greater vibration intensity to mix evenly, so the corresponding vibration tolerance is 1.2. The operator will form a mapping table to match the drug type with the vibration tolerance.
[0044] Vibration tolerance refers to a value that measures a drug's ability to withstand vibration intensity. It is obtained by the processing terminal from a vibration tolerance mapping table based on the drug type. By determining the vibration tolerance, the ability of the current drug type to withstand vibration intensity can be determined, facilitating the subsequent determination of drug solution property parameters.
[0045] Step S201: Determine the pressure resistance coefficient of the medicine bottle based on the correspondence between the medicine bottle material and the preset pressure resistance level of the medicine bottle.
[0046] The relationship between the compressive strength of medicine bottles refers to the correspondence between the bottle material and its compressive strength coefficient. For example, when the bottle is made of glass, it can withstand less force and is easily broken, with a corresponding compressive strength coefficient of 0.7. When the bottle is made of high-strength plastic, it can withstand greater force, with a corresponding compressive strength coefficient of 1.2. Operators create a mapping table that maps the bottle material to its compressive strength coefficient.
[0047] The pressure resistance coefficient of a medicine bottle is a value that measures the pressure a medicine bottle can withstand. It is obtained by the processing terminal from a mapping table corresponding to the pressure resistance of medicine bottles based on the bottle material. By determining the pressure resistance coefficient, the pressure resistance of the medicine bottle can be determined, allowing the medicine to be shaken evenly without damaging the bottle, which is then used to determine the property parameters of the medicine solution.
[0048] Step S202: Calculate the quotient of the light transmittance intensity at the bottom of the bottle and the preset benchmark light transmittance intensity to generate the light transmittance ratio at the bottom of the bottle.
[0049] The bottle bottom transmittance ratio refers to the ratio of the light transmittance of the medicine bottle to that of a standard homogeneous liquid. It is obtained by the processing terminal by calculating the quotient of the bottle bottom transmittance and the reference transmittance. Under the condition that the reference transmittance remains unchanged, the greater the bottle bottom transmittance, the less sedimentation of the medicine solution, and thus the greater the bottle bottom transmittance ratio, which provides data support for subsequent determination of the degree of sedimentation of the medicine solution.
[0050] The reference transmittance refers to the transmittance at the bottom of the empty bottle, which is measured in advance by the operator using a photoelectric sensor. The closer the transmittance at the bottom of the bottle is to the reference transmittance, the less sedimentation occurs, thus providing data support for determining the transmittance ratio at the bottom of the bottle.
[0051] Step S203: Calculate the difference between the preset baseline transmittance ratio and the transmittance ratio at the bottom of the bottle to determine the degree of drug precipitation.
[0052] The degree of sedimentation in the medicine solution refers to the value used to measure the extent of sedimentation in the medicine bottle. It is obtained by calculating the difference between the baseline transmittance and the transmittance at the bottom of the bottle using the processing terminal. With the baseline transmittance remaining constant, the smaller the transmittance at the bottom of the bottle, the lower the light intensity. In this case, the components of the medicine solution that settle at the bottom will reduce the light intensity, resulting in a greater degree of sedimentation. Therefore, a higher degree of sedimentation facilitates the subsequent determination of the medicine solution's property parameters.
[0053] The baseline transmittance ratio refers to the transmittance ratio under ideal conditions, where the light intensity at the bottom of the bottle equals the baseline transmittance intensity. Therefore, in this step, the baseline transmittance ratio is set to 1, which is pre-set by the operator. By determining the baseline transmittance ratio, the current degree of sedimentation in the drug solution is determined, thus providing data support for determining the degree of sedimentation.
[0054] Step S204: Correlate vibration tolerance, bottle pressure resistance coefficient and drug sedimentation degree to generate drug property parameters.
[0055] After determining the degree of drug sedimentation, the drug solution property parameters are obtained by processing the terminal-related vibration tolerance, bottle pressure resistance coefficient, and drug sedimentation degree. By determining these property parameters, the properties of the drug solution in the bottle are determined, which facilitates the subsequent determination of the target vibration frequency, target vibration amplitude, and drug mixing parameters.
[0056] Reference Figure 3 The steps for analyzing the viscosity coefficient and property parameters of the drug solution to determine the target vibration frequency and target vibration amplitude include: Step S300: Determine the degree of sedimentation and vibration tolerance of the drug solution based on the drug solution property parameters.
[0057] In this step, the degree of sedimentation is the same as in step S203. The difference is that in this step, the degree of sedimentation is determined by the processing terminal from the drug property parameters. When the degree of sedimentation is high, stronger vibration should be applied to the drug to improve the uniformity of the mixture during shaking.
[0058] The vibration tolerance in this step is the same as that in step S200. The difference is that in this step, the vibration tolerance is identified and retrieved by the processing terminal from the drug solution property parameters.
[0059] Step S301: Analyze the degree of drug precipitation, the viscosity coefficient of the drug solution, and the vibration tolerance to determine the target vibration frequency.
[0060] After determining the degree of drug sedimentation and vibration tolerance, the processing terminal analyzes the degree of drug sedimentation, viscosity coefficient, and vibration tolerance to obtain the target vibration frequency. The specific method is described in [reference needed]. Figure 4 The steps involve determining the target vibration frequency to determine the number of vibrations per unit time during shaking, which facilitates the subsequent determination of shaking parameters.
[0061] Step S302: Input the degree of drug sedimentation, the target vibration frequency, and the drug viscosity coefficient into the preset comprehensive amplitude function for solution to generate the target vibration amplitude.
[0062] After determining the target vibration frequency, the processing terminal inputs the degree of drug sedimentation, the target vibration frequency, and the drug viscosity coefficient into the comprehensive amplitude function to obtain the target vibration amplitude, thereby determining the total distance moved in space per unit time. This allows for the subsequent determination of the directional amplitude parameter based on the directional amplitude ratio, enabling the selection of different vibration emphasis directions according to different drug properties, thus ensuring the effect of improving the uniformity of the drug during shaking.
[0063] The composite amplitude function is a function used to calculate the amplitude of the target vibration, and can be expressed as follows: ,in Indicates the amplitude of the target vibration. This represents a conversion constant used to ensure that the units on both sides of the composite amplitude function are consistent; it is stored by the operator in the processing terminal. Indicates the degree of precipitation in the medicine solution. Indicates the viscosity coefficient of the drug solution. Indicates the target vibration frequency. Represents the reference overflow constant. This is a very small constant, pre-set by the operator to prevent the denominator from being zero. The greater the degree of sedimentation in the drug solution, the longer the required physical stroke, resulting in a larger target vibration amplitude. Conversely, the higher the viscosity coefficient of the drug solution, the more exponentially the energy required to overcome the resistance of the high-viscosity fluid, thus requiring a longer physical stroke and consequently a larger target vibration amplitude. Furthermore, when both the target vibration frequency and target vibration amplitude are high simultaneously, strong inertia occurs, thereby reducing the target vibration amplitude at higher target vibration frequencies and ensuring improved uniformity during drug mixing.
[0064] Reference Figure 4 The steps for determining the target vibration frequency by analyzing the degree of drug precipitation, the viscosity coefficient of the drug solution, and the vibration tolerance include: Step S400: Analyze the viscosity coefficient of the drug solution, the degree of drug sedimentation, and the preset benchmark overflow constant to determine the frequency influence factor.
[0065] Among them, the frequency influence factor refers to the value that measures the influence of the viscosity coefficient and sedimentation degree of the drug solution on the vibration frequency. It is obtained by analyzing the viscosity coefficient, sedimentation degree, and reference overflow constant of the drug solution at the processing terminal, and can be expressed as follows: ,in Indicates the frequency influence factor. Indicates the degree of precipitation in the medicine solution. Indicates the viscosity coefficient of the drug solution. This represents the baseline overflow constant. The greater the degree of sedimentation in the medicine solution, the higher the required frequency of vibration to provide high-frequency impacts, thereby breaking the adhesion between the sediment and the bottom of the vial. Conversely, the higher the viscosity coefficient of the medicine solution, the more likely high-frequency vibration will generate bubbles locally rather than allowing the solution to flow as a whole, thus requiring a lower frequency. By determining the frequency influence factor, the vibration frequency can be determined based on the degree of sedimentation and viscosity of the medicine solution, thus providing data support for subsequently determining the frequency adjustment term.
[0066] In this step, the reference overflow constant is consistent with the reference overflow constant included in the comprehensive amplitude function in step S302. It is set in advance by the operator to prevent the denominator from being zero.
[0067] Step S401: Calculate the product of the frequency influence factor and the preset frequency gain coefficient to generate a frequency adjustment term.
[0068] The frequency adjustment term refers to the adjustment value of the frequency determined based on the degree of sedimentation and viscosity of the drug solution. It is obtained by calculating the product of the frequency influence factor and the frequency gain coefficient at the processing terminal. By determining the frequency adjustment term, the amount of frequency adjustment under the current degree of sedimentation and viscosity of the drug solution can be determined, thereby providing data support for subsequently determining the adjusted vibration frequency.
[0069] The frequency gain coefficient refers to the increased frequency width determined based on the ratio of sedimentation degree to viscosity, obtained by the operator through prior calibration tests. The calibration test first uses test solutions with the same viscosity gradient and sedimentation degree. Then, the vibration frequency of the drug mixing device is adjusted until a uniform mixing effect is achieved, and no air bubbles are present in the solution. Multiple sets of experimental data points are recorded, where the X-axis represents the ratio of sedimentation degree to viscosity coefficient, and the Y-axis represents the vibration frequency. A scatter plot is drawn, and a linear regression is performed using the least squares method. The slope obtained from the fitted data is the value of the frequency gain coefficient. Furthermore, to convert the frequency influence factor into a frequency adjustment amount, the unit of the frequency gain coefficient is defined as... This is to facilitate subsequent determination and adjustment of the vibration frequency.
[0070] Step S402: Calculate the sum of the frequency adjustment term and the preset reference starting frequency to generate the adjusted vibration frequency.
[0071] The adjustment of the vibration frequency refers to the vibration frequency determined based on the sedimentation degree and viscosity of the drug solution. This frequency is calculated by the processing terminal by combining the frequency adjustment item with the reference starting frequency. By determining the adjusted vibration frequency, uneven mixing due to differences in the properties of the drug solution can be effectively avoided, thereby ensuring improved uniformity during drug mixing.
[0072] The reference starting frequency refers to the frequency corresponding to the lowest stable operating point of the vibratory motor, which is obtained by the operator from the specifications provided by the vibratory motor manufacturer. By determining the reference starting frequency, the minimum starting frequency of the vibratory motor can be determined, so that the adjusted vibration frequency can be determined according to the frequency adjustment parameters.
[0073] Step S403: Obtain the maximum frequency of the motor.
[0074] The maximum frequency of the motor refers to the maximum vibration frequency of the vibratory motor, which is obtained by the operator from the specifications provided by the vibratory motor manufacturer. By determining the maximum frequency of the motor, the maximum vibration frequency that the medicine can tolerate can be determined, thus providing data support for subsequently determining the maximum vibration frequency.
[0075] Step S404: Calculate the product of vibration tolerance and the maximum frequency of the motor to generate the maximum vibration frequency.
[0076] The maximum vibration frequency refers to the highest vibration frequency that the drug can tolerate, which is obtained by calculating the vibration tolerance and the maximum frequency of the motor at the processing terminal. Under the condition that the maximum frequency of the motor remains unchanged, the higher the vibration tolerance, the greater the drug's ability to withstand vibration intensity, and thus the higher the vibration frequency it can tolerate, thereby providing data support for subsequently determining the target vibration frequency.
[0077] Step S405: Sort the adjusted vibration frequency and the maximum vibration frequency to determine the minimum vibration frequency, and define the minimum vibration frequency as the target vibration frequency.
[0078] In this process, after determining the maximum vibration frequency, the processing terminal sorts the adjusted vibration frequencies and the maximum vibration frequency to determine the minimum vibration frequency, and defines the minimum vibration frequency as the target vibration frequency. This ensures that the optimal vibration frequency is determined based on the degree of sedimentation and viscosity, while not exceeding the drug's tolerance to frequency, thereby guaranteeing the effect of improving the uniformity of the drug during shaking.
[0079] The minimum vibration frequency refers to the smaller of the adjusted and maximum vibration frequencies, obtained by sorting the adjusted and maximum vibration frequencies at the processing terminal. By determining the minimum vibration frequency, the optimal vibration frequency can be selected within the tolerance range of the drug, thereby ensuring the effect of improving the uniformity of the drug during shaking.
[0080] Reference Figure 5 The steps for determining the drug mixing parameters by analyzing the drug solution viscosity coefficient, drug solution property parameters, target vibration frequency, and target vibration amplitude include: Step S500: Determine the degree of precipitation of the medicine solution and the pressure resistance coefficient of the medicine bottle based on the property parameters of the medicine solution.
[0081] In this step, the degree of drug sedimentation is the same as in step S203. The difference is that in this step, the degree of sedimentation is identified and retrieved from the drug property parameters by the processing terminal. When the degree of sedimentation is large, a larger amplitude should be matched in the vertical direction to better counteract gravity and thus ensure the uniformity of the drug during shaking.
[0082] The pressure resistance coefficient of the medicine bottle in this step is the same as that in step S201. The difference is that in this step, the pressure resistance coefficient is identified and retrieved from the drug liquid property parameters by the processing terminal. The pressure resistance coefficient of the medicine bottle is strongly correlated with the final clamping force. The larger the pressure resistance coefficient, the greater the clamping force that the medicine bottle can withstand, thus providing data support for determining the final clamping force.
[0083] Step S501: Calculate the quotient of the viscosity coefficient of the liquid and the degree of sedimentation of the liquid to generate the directional amplitude ratio.
[0084] The directional amplitude ratio refers to the ratio of horizontal to vertical amplitude, which is obtained by calculating the quotient of the drug viscosity coefficient and the degree of drug sedimentation at the processing terminal. When the drug viscosity coefficient is higher, the viscous resistance between drug layers is greater, thus requiring shear force in the horizontal direction to break down the resistance. Conversely, when the degree of drug sedimentation is greater, a larger amplitude should be matched in the vertical direction to better counteract gravity, thereby ensuring the uniformity of the drug during shaking.
[0085] Step S502: Determine whether the direction amplitude ratio is less than the preset reference amplitude ratio.
[0086] The reference amplitude ratio refers to the amplitude ratio that measures the balance between the viscosity coefficient and the degree of sedimentation of the drug solution. In this step, the reference amplitude ratio is set to 1, which is predetermined by the operator. By determining whether the directional amplitude ratio is less than the reference amplitude ratio, the relative importance of the current drug solution viscosity and sedimentation degree is determined. This allows for the subsequent determination of the amplitude in different directions based on the directional amplitude ratio, thereby ensuring the uniformity of the drug during shaking.
[0087] Step S5021: If it is less than, the ratio of the target vibration amplitude to the directional amplitude is input into the preset vertical equation set for solution to determine the directional amplitude parameter.
[0088] If the directional amplitude ratio is less than the reference amplitude ratio, it indicates that the current precipitation is severe and the viscosity is low. In this case, a larger vibration amplitude should be given in the vertical direction. Therefore, the processing terminal inputs the target vibration amplitude and the directional amplitude ratio into the vertical equation system to obtain the directional amplitude parameter, thereby making the amplitude in the vertical direction larger to better combat drug precipitation and thus ensure the effect of improving the uniformity of the drug when shaken.
[0089] The directional amplitude parameter refers to the amplitude of the drug shaking device in different directions during shaking, including the horizontal amplitude and the vertical amplitude. It is obtained by inputting the target vibration amplitude and the ratio of directional amplitude into the vertical equation system by the processing terminal to solve, so as to facilitate the subsequent determination of the drug shaking parameters.
[0090] The vertical equations are a set of equations used to solve for the direction and amplitude parameters. They are stored by the operator on the processing terminal and can be represented as follows: , ,in Indicates the amplitude in the vertical direction. Indicates the amplitude in the horizontal direction. Indicates the amplitude of the target vibration. The ratio of directional amplitude indicates that, under the condition that the target vibration amplitude remains constant, the smaller the ratio of directional amplitude, the greater the degree of drug precipitation. This results in a larger vertical amplitude, which better counteracts drug precipitation and ensures the uniformity of the drug when shaken.
[0091] Step S5022: If it is not less than, then input the ratio of the target vibration amplitude to the directional amplitude into the preset horizontal equation set for solving, so as to determine the directional amplitude parameter.
[0092] If the directional amplitude ratio is not less than the reference amplitude ratio, it indicates that the current drug solution has high viscosity and low precipitation. In this case, a larger vibration amplitude should be given in the horizontal direction to effectively break the viscous resistance between the drug solution layers. The processing terminal inputs the target vibration amplitude and directional amplitude ratio into the horizontal equation set to obtain the directional amplitude parameter, so as to determine the drug shaking parameters in the future.
[0093] The directional amplitude parameter in this step is the same as that in step S5021. The difference is that in this step, the directional amplitude parameter is obtained by the processing terminal inputting the ratio of the target vibration amplitude to the directional amplitude into the horizontal equation system and solving it.
[0094] The horizontal equations are a set of equations used to solve for the directional amplitude parameters. They are stored by the operator on the processing terminal and can be represented as follows: , ,in Indicates the amplitude in the vertical direction. Indicates the amplitude in the horizontal direction. Indicates the amplitude of the target vibration. The ratio of directional amplitude indicates that, under the condition that the target vibration amplitude remains constant, the larger the ratio of directional amplitude, the greater the viscosity of the liquid, which in turn results in a larger horizontal amplitude and a smaller vertical amplitude, thereby giving a larger horizontal vibration amplitude to effectively break the viscous resistance between the liquid layers.
[0095] Step S503: Analyze the pressure resistance coefficient of the medicine bottle, the target vibration frequency, and the target vibration amplitude to determine the final clamping force.
[0096] The final clamping force refers to the final clamping force of the clamping assembly on the medicine bottle, which is obtained by the processing terminal after analyzing the compressive strength coefficient of the medicine bottle, the target vibration frequency, and the target vibration amplitude. The specific method is described in [reference needed]. Figure 6 The steps involve determining the final clamping force to find the optimal force based on the bottle material, ensuring stability and preventing damage to the bottle during shaking.
[0097] Step S504: Associate the directional amplitude parameters, target vibration frequency, and final clamping force to generate drug mixing parameters.
[0098] In this process, after determining the final clamping force, the drug mixing parameters are obtained by processing the terminal-associated directional amplitude parameters, the target vibration frequency, and the final clamping force. By determining the drug mixing parameters, the control parameters of the drug mixing device during drug mixing are determined, thereby effectively avoiding uneven mixing caused by different drug properties and ensuring improved uniformity during drug mixing.
[0099] Reference Figure 6The steps to determine the final clamping force by analyzing the pressure resistance coefficient of the medicine bottle, the target vibration frequency, and the target vibration amplitude include: Step S600: Analyze the target vibration frequency and target vibration amplitude to determine the inertial acceleration.
[0100] Among them, inertial acceleration refers to the inertial acceleration generated at the instant of changing direction under the target vibration frequency and target vibration amplitude when the medicine is shaken. It is obtained by the processing terminal after analyzing the target vibration frequency and target vibration amplitude, and can be expressed as follows: When the target vibration frequency and target vibration amplitude are greater, the inertial acceleration generated is greater, and thus the acceleration of the medicine bottle attempting to detach from the clamping component at the target vibration frequency and target vibration amplitude is greater, thereby providing data support for the subsequent determination of the theoretical clamping force.
[0101] Step S601: Obtain the quality of the medicine bottle.
[0102] Among them, the bottle mass refers to the mass of the bottle and the liquid medicine to be tested, which is obtained by the operator in advance using measuring tools to measure the medicine to be tested. The bottle mass is strongly correlated with the theoretical clamping force; the greater the bottle mass, the greater the clamping force required, thus providing data support for the subsequent determination of the theoretical clamping force.
[0103] Step S602: Analyze the mass and inertial acceleration of the medicine bottle to determine the theoretical clamping force.
[0104] The theoretical clamping force refers to the clamping force exerted by the clamping components on the medicine bottle, determined based on the bottle's mass. This force is obtained by analyzing the bottle's mass and inertial acceleration at the processing terminal. Specific methods are detailed in [reference needed]. Figure 7 The steps are as follows. The clamping assembly secures the medicine bottle by using static friction with the bottle's surface. The greater the mass of the medicine bottle, the greater the required static friction. Therefore, the clamping force required is determined based on the bottle's mass and inertial acceleration, thereby ensuring and improving the stability of the medicine bottle during the shaking process.
[0105] Step S603: Calculate the product of the pressure resistance coefficient of the medicine bottle and the preset maximum clamping force of the motor to generate the maximum force on the medicine bottle.
[0106] The maximum force on the medicine bottle refers to the maximum clamping force that the bottle material can withstand. It is obtained by calculating the product of the bottle's compressive strength coefficient and the motor's maximum clamping force using the processing terminal. Under the condition that the motor's maximum clamping force remains constant, the larger the bottle's compressive strength coefficient, the greater the clamping force the bottle can withstand, and thus the greater the maximum force on the bottle, which facilitates the subsequent determination of the final clamping force.
[0107] The maximum clamping force of the motor refers to the maximum force that the clamping assembly can output under the influence of the vibrating motor, which is obtained by the operator through prior calibration tests. First, under full load of the vibrating motor, the maximum stable clamping force of the clamping assembly needs to be measured using a force sensor. The maximum stable clamping force measured at this time is the maximum clamping force of the motor. By determining the maximum clamping force of the motor, the maximum force that the clamping assembly can output under the influence of the vibrating motor can be determined, thus providing data support for determining the maximum force on the medicine bottle.
[0108] Step S604: Sort the theoretical clamping force and the maximum force on the medicine bottle to determine the minimum clamping force, and define the minimum clamping force as the final clamping force.
[0109] In this process, after determining the maximum force on the medicine bottle, the processing terminal sorts the theoretical clamping force and the maximum force on the medicine bottle to obtain the minimum clamping force, and defines the minimum clamping force as the final clamping force. Thus, within the clamping force range that the medicine bottle can withstand, the optimal clamping force is selected to ensure the stability of the medicine bottle during the shaking process.
[0110] The minimum clamping force refers to the minimum of the theoretical clamping force and the maximum force that the medicine bottle can withstand. It is obtained by sorting the theoretical clamping force and the maximum force that the medicine bottle can withstand from the processing terminal. By determining the minimum clamping force, an optimal clamping force within the clamping force range that the medicine bottle can withstand is determined, thereby ensuring that the medicine can be shaken evenly without damaging the medicine bottle.
[0111] Reference Figure 7 The steps for analyzing the mass and inertial acceleration of the medicine bottle to determine the theoretical clamping force include: Step S700: Calculate the sum of inertial acceleration and preset gravitational acceleration to generate resultant acceleration.
[0112] The resultant acceleration refers to the acceleration generated by the total inertial force that needs to be overcome when the medicine shaker vibrates up and down during the shaking process. It is obtained by the processing terminal by calculating the sum of the inertial acceleration and the gravitational acceleration. When the medicine is shaken, the clamping assembly must overcome not only the downward inertial force but also the gravity of the medicine itself at the moment of upward vibration, so as to determine the maximum effective resultant force.
[0113] Gravitational acceleration refers to the acceleration caused by gravity on a freely falling drug, which is stored by the operator in the processing terminal. By determining gravitational acceleration, the total inertial force that needs to be overcome when the drug is shaken can be determined, thus providing data support for determining the resultant acceleration.
[0114] Step S701: Calculate the product of the resultant acceleration and the mass of the medicine bottle to generate the maximum effective resultant force.
[0115] The maximum effective resultant force refers to the sum of the inertial force and gravity that the clamping component must overcome when the medicine is shaken, which is obtained by calculating the product of the resultant force acceleration and the mass of the medicine bottle from the processing terminal. Under the condition that the mass of the medicine bottle remains constant, the greater the resultant force acceleration, the greater the inertial force that the clamping component needs to overcome when the medicine is shaken, so as to facilitate the subsequent determination of the initial clamping force.
[0116] Step S702: Calculate the quotient of the maximum effective resultant force and the preset friction coefficient of the medicine bottle to generate the initial clamping force.
[0117] The initial clamping force refers to the force applied to the medicine bottle by the clamping assembly, determined based on the static friction force on the bottle's surface. It is obtained by calculating the product of the maximum effective net force and the bottle's mass from the processing terminal. Since the clamping assembly fixes the medicine bottle through the static friction force on its surface, which is the maximum effective net force, and the static friction force equals the product of the initial clamping force and the bottle's coefficient of friction, under the condition that the bottle's coefficient of friction remains constant, a larger maximum effective net force indicates a larger static friction force between the bottle and the clamping assembly, thus requiring a larger initial clamping force. This provides data support for subsequently determining the theoretical clamping force.
[0118] The coefficient of friction of a medicine bottle is a value that measures the ability of the clamping assembly and the medicine bottle material to resist relative sliding. It is obtained by the operator from a material friction coefficient table. By determining the coefficient of friction of the medicine bottle, it can be seen that the higher the coefficient of friction, the greater the frictional force between the medicine bottle and the clamping assembly. Therefore, a smaller clamping force is required to ensure the stability of the medicine bottle, thus providing data support for determining the initial clamping force.
[0119] The material friction coefficient table in this step refers to a table that stores the friction coefficients between materials. For example, the friction coefficient between rubber and dry glass is 0.7, and the friction coefficient between smooth metal and glass is 0.2, so that operators can easily find the friction coefficient of the medicine bottle.
[0120] Step S703: Calculate the product of the initial clamping force and the preset liquid sloshing safety factor to generate the theoretical clamping force.
[0121] After determining the initial clamping force, the processing terminal calculates the product of the initial clamping force and the liquid shaking safety factor to generate the theoretical clamping force. When the medicine shaking device controls the clamping component to move to the left, the liquid will lag due to inertia and accumulate on the right side of the medicine bottle. If only the initial clamping force is applied, the medicine bottle may slide due to the sudden change in force at the moment the liquid lags. Therefore, it is necessary to use the liquid shaking safety factor to counteract the impact force generated by the liquid during shaking, thereby ensuring the stability of the medicine bottle when the medicine is shaken.
[0122] The liquid shaking safety factor is a coefficient used to compensate for the impact force generated when the liquid is shaken. It is set in advance by the operator based on the amount of liquid in the bottle. For example, when the bottle is full, the liquid behaves almost like a rigid body when shaken, and the impact force is very small. In this case, the liquid shaking safety factor is set to 1.0. When the bottle is half full, there is enough space for the liquid to shake when shaken, and the impact force is larger. In this case, the liquid shaking safety factor is set to 1.4, which effectively counteracts the impact force generated when the liquid is shaken, thus ensuring the stability of the bottle when the medicine is shaken.
[0123] Based on the same inventive concept, embodiments of this application provide a multi-directional drug mixing system, including: The acquisition module is used to acquire information such as drug type, bottle material, drug viscosity coefficient, light transmittance at the bottom of the bottle, maximum motor frequency, and bottle mass. Memory for storing programs based on multi-directional drug mixing methods; The processor can load and execute programs in memory to implement a multi-directional drug mixing method.
[0124] Those skilled in the art will clearly understand that, for the sake of convenience and brevity, the above-described division of functional modules is used as an example. In practical applications, the above functions can be assigned to different functional modules as needed, that is, the internal structure of the device can be divided into different functional modules to complete all or part of the functions described above. The specific working process of the system, device, and unit described above can be referred to the corresponding process in the foregoing method embodiments, and will not be repeated here.
[0125] This application provides a computer-readable storage medium storing a computer program that can be loaded and executed by a processor, based on a multi-directional drug mixing method.
[0126] Computer storage media include, for example, USB flash drives, portable hard drives, read-only memory (ROM), random access memory (RAM), magnetic disks, optical disks, and other media that can store program code.
[0127] Based on the same inventive concept, embodiments of this application provide a smart terminal, including a memory and a processor, wherein the memory stores a computer program that can be loaded and executed by the processor based on a multi-directional drug shaking method.
[0128] Those skilled in the art will clearly understand that, for the sake of convenience and brevity, the above-described division of functional modules is used as an example. In practical applications, the above functions can be assigned to different functional modules as needed, that is, the internal structure of the device can be divided into different functional modules to complete all or part of the functions described above. The specific working process of the system, device, and unit described above can be referred to the corresponding process in the foregoing method embodiments, and will not be repeated here.
[0129] The above are all preferred embodiments of this application and are not intended to limit the scope of protection of this application. Any feature disclosed in this specification (including the abstract and drawings) may be replaced by other equivalent or similar features unless specifically stated otherwise. That is, unless specifically stated otherwise, each feature is only one example of a series of equivalent or similar features.
Claims
1. A drug mixing method based on multi-directional shaking, characterized in that, include: Obtain information such as drug type, bottle material, drug viscosity coefficient, and light transmittance at the bottom of the bottle; The drug type, bottle material, and light transmittance at the bottom of the bottle were analyzed to determine the property parameters of the drug solution. The viscosity coefficient and property parameters of the drug solution are analyzed to determine the target vibration frequency and target vibration amplitude. The viscosity coefficient, property parameters, target vibration frequency, and target vibration amplitude of the drug solution are analyzed to determine the parameters for drug mixing. The preset drug shaking device is controlled according to the drug shaking parameters to shake the preset medicine bottle in multiple directions.
2. The multi-directional drug mixing method according to claim 1, characterized in that, The steps for analyzing the type of drug, the material of the medicine bottle, and the light transmittance at the bottom of the bottle to determine the property parameters of the drug solution include: The vibration tolerance is determined based on the correspondence between the drug type and the preset vibration tolerance. The compressive strength coefficient of the medicine bottle is determined based on the correspondence between the material of the medicine bottle and the preset compressive strength of the medicine bottle; Calculate the quotient of the light transmittance intensity at the bottom of the bottle and the preset benchmark light transmittance intensity to generate the light transmittance ratio at the bottom of the bottle; Calculate the difference between the preset baseline transmittance and the transmittance at the bottom of the bottle to determine the degree of drug precipitation; Correlate vibration tolerance, bottle pressure resistance coefficient, and drug sedimentation degree to generate drug property parameters.
3. The multi-directional drug mixing method according to claim 1, characterized in that, The steps for analyzing the viscosity coefficient and property parameters of the drug solution to determine the target vibration frequency and target vibration amplitude include: Determine the degree of sedimentation and vibration tolerance of the drug solution based on its property parameters; The degree of drug sedimentation, viscosity coefficient, and vibration tolerance of the drug solution were analyzed to determine the target vibration frequency. The degree of drug sedimentation, the target vibration frequency, and the viscosity coefficient of the drug solution are input into a preset comprehensive amplitude function for solution to generate the target vibration amplitude.
4. The multi-directional drug mixing method according to claim 3, characterized in that, The steps for determining the target vibration frequency by analyzing the degree of drug precipitation, the viscosity coefficient of the drug solution, and the vibration tolerance include: The viscosity coefficient, sedimentation degree, and preset benchmark overflow constant of the drug solution were analyzed to determine the frequency influencing factor. Calculate the product of the frequency influence factor and the preset frequency gain coefficient to generate the frequency adjustment term; The sum of the frequency adjustment term and the preset reference starting frequency is calculated to generate the adjusted vibration frequency; Get the maximum frequency of the motor; Calculate the product of vibration tolerance and the maximum frequency of the motor to generate the maximum vibration frequency; The adjusted vibration frequencies and the maximum vibration frequencies are sorted to determine the minimum vibration frequency, and the minimum vibration frequency is defined as the target vibration frequency.
5. The multi-directional drug mixing method according to claim 1, characterized in that, The steps for determining the drug mixing parameters by analyzing the drug solution viscosity coefficient, drug solution property parameters, target vibration frequency, and target vibration amplitude include: Determine the degree of sedimentation of the medicine solution and the pressure resistance coefficient of the medicine bottle based on the property parameters of the medicine solution; Calculate the quotient of the viscosity coefficient of the drug solution and the degree of sedimentation of the drug solution to generate the directional amplitude ratio; Determine whether the direction amplitude ratio is less than the preset reference amplitude ratio; If it is less than 1, the ratio of the target vibration amplitude to the directional amplitude is input into the preset vertical equation set for solution to determine the directional amplitude parameter. If it is not less than, the ratio of the target vibration amplitude to the directional amplitude is input into the preset horizontal equation set for solving to determine the directional amplitude parameter; The compressive strength coefficient of the medicine bottle, the target vibration frequency, and the target vibration amplitude are analyzed to determine the final clamping force; The associated directional amplitude parameters, target vibration frequency, and final clamping force are used to generate drug mixing parameters.
6. The multi-directional drug mixing method according to claim 5, characterized in that, The steps to determine the final clamping force by analyzing the pressure resistance coefficient of the medicine bottle, the target vibration frequency, and the target vibration amplitude include: The target vibration frequency and amplitude are analyzed to determine the inertial acceleration; Obtain the quality of the medicine bottle; The mass and inertial acceleration of the medicine bottle were analyzed to determine the theoretical clamping force; Calculate the product of the pressure resistance coefficient of the medicine bottle and the preset maximum clamping force of the motor to generate the maximum force on the medicine bottle; The theoretical clamping force and the maximum force on the medicine bottle are ranked to determine the minimum clamping force, and the minimum clamping force is defined as the final clamping force.
7. The multi-directional drug mixing method according to claim 6, characterized in that, The steps to analyze the mass and inertial acceleration of the medicine bottle to determine the theoretical clamping force include: Calculate the sum of inertial acceleration and preset gravitational acceleration to generate resultant acceleration; Calculate the product of the resultant acceleration and the mass of the medicine bottle to generate the maximum effective resultant force; Calculate the quotient of the maximum effective resultant force and the preset friction coefficient of the medicine bottle to generate the initial clamping force; Calculate the product of the initial clamping force and the preset safety factor for liquid sloshing to generate the theoretical clamping force.
8. A multi-directional drug mixing system, characterized in that, include: The acquisition module is used to acquire information such as drug type, bottle material, drug viscosity coefficient, and light transmittance at the bottom of the bottle. A memory for storing the program of the multi-directional drug mixing method as described in any one of claims 1 to 7; The processor and the program in the memory are capable of being loaded and executed by the processor to implement the multi-directional drug shaking method as described in any one of claims 1 to 7.
9. A smart terminal, characterized in that, It includes a memory and a processor, wherein the memory stores a computer program that can be loaded by the processor and executed as described in any one of claims 1 to 7, based on a multidirectional drug shaking method.
10. A computer-readable storage medium, characterized in that, The computer program is stored that can be loaded by a processor and executed as described in any one of claims 1 to 7, based on a multi-directional drug mixing method.