A method for synthesizing 2,6-dimethoxypyridine-4-boronic acid

CN122940774APending Publication Date: 2026-10-20BINHAI GL PEPTIDE LTD
View PDF 1 Cites 0 Cited by

Patent Information

Application Number
CN202611070335.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-07-18
Publication Date
2026-10-20

Smart Images

  • Figure FT_1
    Figure FT_1
  • Figure FT_2
    Figure FT_2
  • Figure FT_3
    Figure FT_3
Patent Text Reader

Abstract

This invention discloses for the first time a method for synthesizing 2,6-dimethoxypyridine-4-boronic acid. It primarily addresses the technical problem of lacking an effective synthetic method for this compound. The invention is achieved through the following technical solution: First, 2,6-dimethoxypyridine is dissolved in acetonitrile and chlorinated with NCS to obtain 2,6-dimethoxy-3-chloropyridine; Second, 2,6-dimethoxy-3-chloropyridine is dissolved in tetrahydrofuran and reacted with n-hexane under alkaline conditions with a borate ester to obtain 2,6-dimethoxy-3-chloropyridine-4-boronic acid; Third, 2,6-dimethoxy-3-chloropyridine-4-boronic acid is dissolved in a solvent and hydrogenated to obtain 2,6-dimethoxypyridine-4-boronic acid.
Need to check novelty before this filing date? Find Prior Art

Citation Information

Patent Citations

  • Compounds and compositions for treating conditions associated with LPA receptor activity

    WO2023160672A1