Method of cleaning a dental surface

Abstract

This application provides a tooth surface cleaning method that can effectively whiten teeth without damaging the tooth surface and effectively prevent and cure periodontal disease and other diseases. The invention relates to a tooth surface cleaning method that cleans by spraying dental spray powder onto the supragingival and / or subgingival tooth surfaces, wherein the dental spray powder contains raffinose. Furthermore, the dental spray powder further comprises one or more of silicon, titanium, or bioactive glass. The median particle size of the raffinose is preferably 10 μm to 100 μm.

Description

Technical Field

[0001] This invention relates to a method for cleaning tooth surfaces by spraying dental spray powder onto the tooth surface above and / or below the gingival margin. Background Technology

[0002] In recent years, powder spraying has been widely used as a method for cleaning tooth surfaces or root surfaces. Because powder spraying can quickly and effectively remove stains, tartar, and plaque, it has become an alternative or auxiliary technology to mechanical tooth cleaning methods such as handheld instruments or ultrasonic cleaning.

[0003] Tooth surface cleaning methods that utilize compressed air to spray micro-powder particles and water can generally be divided into jet cutting using so-called "air abrasion" and jet polishing using "air polishing". These methods are based on the principle that the mixture of powder and compressed air is impacted on the tooth surface (root surface) by jetting water, thereby cutting away enamel and dentin and removing deposits attached to the tooth surface (root surface).

[0004] The powders used in the aforementioned tooth surface cleaning methods are composed of various substances, such as sodium bicarbonate or calcium carbonate. While sodium bicarbonate and calcium carbonate are well-tolerated by patients, they can cause surface abrasion when cleaning the root or dentin surfaces.

[0005] In addition, products containing sugars, such as disaccharides (see Patent Document 1) or oligosaccharides (see Patent Document 2), have been proposed as dental spray powders. Although such dental spray powders utilizing sugars are based on the biocompatibility of sugars, depending on the type of sugar, while effective in cleaning tooth surfaces, they may damage the dental overlay restorations used for treatment, i.e., so-called crowns.

[0006] Furthermore, while the current technology for cleaning tooth surfaces using traditional dental spray powder aims to whiten teeth after cleaning—in other words, to improve the aesthetics of the cleaned teeth by removing plaque—it has not yet achieved a fully satisfactory result.

[0007] Moreover, there is an urgent need for a tooth surface cleaning technology that can effectively prevent and cure periodontal disease through tooth surface cleaning.

[0008] [Existing Technical Documents]

[0009] [Patent Literature]

[0010] Patent Document 1: Japanese Patent Publication No. 2017-531690

[0011] Patent Document 2: Japanese Patent Application Publication No. 2021-91741. Summary of the Invention

[0012] [The problem that the invention aims to solve]

[0013] The present invention was made based on the above background, and its purpose is to provide a tooth surface cleaning method. This method, which utilizes powder spraying tooth surface cleaning technology, can effectively clean the tooth surface or the surface of tooth covering restorations without damaging it, and can also effectively whiten teeth and effectively prevent and cure periodontal diseases.

[0014] [Methods used to solve problems]

[0015] The inventors conducted in-depth research on oligosaccharides for dental spray powder materials and found that raffinose, a type of oligosaccharide, is very effective for cleaning tooth surfaces, thus conceiving and obtaining this invention.

[0016] This invention relates to a tooth surface cleaning method, wherein: in a tooth surface cleaning method of spraying dental spray powder onto the upper and / or lower gingival margin tooth surfaces for cleaning, dental spray powder containing raffinose is used.

[0017] The dental spray powder of this invention contains raffinose, an oligosaccharide extracted from plants and used in food and cosmetics, therefore it poses no problem for use in the oral cavity. Furthermore, unlike other oligosaccharides, this raffinose has low hygroscopicity and relatively low crystal hardness. Additionally, it has the property of forming a layered liquid crystal structure when adhering to the tooth surface. Moreover, it is less likely to trigger the Maillard reaction (browning reaction) caused by sugars.

[0018] The dental spray powder used in the tooth surface cleaning method of this invention is typically made from a mixture of raffinose, an anti-caking agent, or a surfactant. Most sugars, except for raffinose, have high water absorption; therefore, when used in the oral cavity, they tend to become viscous due to their temperature and moisture content, close to body temperature, and are therefore considered insufficient for effective tooth surface cleaning. However, because raffinose has low water absorption, it is very suitable as a dental spray powder. Furthermore, because raffinose crystals have relatively low hardness, they can prevent scratching of tooth surfaces or crowns.

[0019] The tooth surface cleaning method of this invention uses dental spray powder containing raffinose, so that during tooth surface cleaning, the raffinose adheres to the tooth surface and periodontal tissues. It is known that this raffinose forms a laminar liquid crystal structure, which can act as a barrier against the tooth surface epithelium. Furthermore, by penetrating into the periodontal pockets, the barrier effect of the laminar liquid crystal structure is expected to prevent and cure periodontal disease. Moreover, because raffinose appears transparent or white under the laminar liquid crystal structure and is not prone to the Maillard reaction, the whiteness of the cleaned tooth surface can be maintained for a long time.

[0020] In the tooth surface cleaning method of the present invention, the dental aerosol powder preferably contains at least one of silicon or titanium, or bioactive glass. Silicon or titanium can be contained in the dental aerosol powder in the form of silicon dioxide (SiO2) or titanium dioxide (TiO2), and the whitening effect of the tooth surface can be further enhanced by containing these materials. For example, when proteins that have penetrated into the enamel cylindrical sheaths are removed by the dental aerosol powder of the present invention, the silicon or titanium adhering to the enamel cylindrical sheaths will cause diffuse reflection of natural light, tending to make the tooth surface appear whiter. Furthermore, since the lamellar liquid crystal structure of raffinose is known to readily absorb inorganic substances, silicon or titanium can be effectively adhered to the tooth surface.

[0021] Furthermore, bioactive glass, an absorbent synthetic material composed of metal oxides, is currently used in dentistry and medicine as a biomaterial for repairing bone defects and treating skin injuries. By combining this bioactive glass with raffinose and incorporating it into dental spray powder, tooth surface cleaning can be performed without damaging the tooth surface or crown. Moreover, based on the affinity and easy binding of bioactive glass to raffinose, it is expected that their interaction with cells will change, thereby improving the healing function of areas with tooth defects.

[0022] The raffinose contained in the dental spray powder of the present invention, due to its hydrophobic nature and stability in hydrate one to hydrate five states, can exert the following effects when combined with bioactive glass. Because the surface of bioactive glass contains Si-OH and Ca... 2＋Raffinose interacts with the hydroxyl groups (-OH) of raffinose, facilitating the binding of bioactive glass to raffinose through hydrogen bonding and interionic interactions. Furthermore, raffinose vitrification and the adsorption reaction between bioactive glass and the tooth surface tend to form a protective film. Therefore, by regulating the dissolution behavior and ion dissolution of bioactive glass, not only can the function of bioactive glass be enhanced, but damage to tooth surfaces or crowns caused by hard bioactive glass can also be inhibited. Moreover, the presence of raffinose can increase the hydrophilicity of bioactive glass and alter its interaction with cells, potentially improving the healing function of tooth defects. In addition, since raffinose tends to protect biomolecules in a dry state, it can also improve the shelf life of dental spray powders containing bioactive glass.

[0023] The raffinose used in the tooth surface cleaning method of this invention preferably has a median particle size (D50) between 10 μm and 100 μm. This is because if it is less than 10 μm, the tooth surface cleaning ability tends to decrease, and if it exceeds 100 μm, the aggression to the tooth surface increases. Furthermore, if a dental spray powder is made primarily of raffinose, the raffinose content is preferably between 70% and 99.9% by weight. This is because if it is less than 70% by weight, the tooth surface cleaning ability tends to decrease, and if it exceeds 99.9% by weight, the intercrystalline density increases, and the operability tends to deteriorate. If the dental spray powder is not primarily composed of raffinose but rather of a mixture of materials, the raffinose content can also be less than 70% by weight. For example, a dental spray powder can be made from a mixture of 80% by weight of bioactive glass and 20% by weight of raffinose. In this case, although the properties of the mixed material itself (the properties of the bioactive glass) will have a preferential effect, a dental spray powder with controlled properties of the mixed material can still be made by adjusting the presence and content of raffinose.

[0024] In the tooth surface cleaning method of this invention, it is effective to irradiate the cleaned tooth surface with laser after cleaning it with dental spray powder. After the tooth surface cleaning method of this invention is completed, irradiating the cleaned tooth surface with a laser of a specific wavelength can enhance the barrier effect of the tooth surface through crystallization caused by the molecular fusion of raffinose, silicon, titanium, bioactive glass, etc., attached to the tooth surface. The wavelength of the irradiated laser is preferably controlled in conjunction with the substances contained in the dental spray powder.

[0025] [Invention Benefits]

[0026] The tooth surface cleaning method according to the present invention can clean the tooth surface without damaging the tooth surface or tooth covering restorations, effectively achieve teeth whitening, and effectively prevent and cure periodontal disease and other diseases. Attached Figure Description

[0027] Figure 1 Scanning electron microscope (SEM) images of aluminum substrate surface cleaning tests

[0028] Figure 2 An observation photograph of the copper substrate surface after cleaning.

[0029] Figure 3 An observation photograph of the copper substrate surface after cleaning.

[0030] Figure 4 Oral cavity observation photos three months after tooth cleaning

[0031] Figure 5 Oral cavity observation photos three months after tooth cleaning Detailed Implementation

[0032] First, in order to confirm the cutting force of raffinose on the tooth surface, the results of the cleaning test conducted on the aluminum substrate surface are explained below.

[0033] The sample used in this cleaning test was an aluminum substrate measuring 50mm × 25mm and 0.5mm thick. The surface of the aluminum substrate had strip-shaped grinding marks, and the cleaning test was performed on the substrate whose surface was marked black with an oil-based marker.

[0034] The dental spray powders used in the cleaning test included the following three types: raffinose powder with a content of 98% or higher, calcium carbonate powder with a content of 98% or higher as a control group, and erythritol powder with a content of 98% or higher.

[0035] These three types of dental spray powders were used to spray the surface of an aluminum substrate for surface cleaning. The spraying device was a commercially available dental spray cutter (product name "Aquacare", manufactured by Medivance Instruments, UK), with a handle inner diameter of 0.8 mm, a spray pressure of 2.0 MPa, and a spray distance of 10 mm. The water volume was set to the medium level indicated on the spraying device's scale.

[0036] Figure 1 This image shows a scanning electron microscope (SEM) image (500x magnification) of the surface of an aluminum substrate that underwent a cleaning test. Figure 1 Part (A) shows the surface of the aluminum substrate before the cleaning test, part (B) shows the case of calcium carbonate, part (C) shows the case of erythritol (an alditol), and part (D) shows the case of raffinose.

[0037] like Figure 1As shown in section (A), after the cleaning test, the original strip-shaped grinding marks on the surface of each substrate have disappeared. In the case of calcium carbonate in section (B) and erythritol in section (C), the grinding marks almost completely disappeared. On the other hand, in the case of raffinose in section (D), only the strip-shaped grinding marks became fainter and more visible, showing a cleaning effect.

[0038] The study on physical crystallization strength at room temperature (20°C) (Journal of Cryobiology and Cryotechnology, VOL. 66, No. 1, 1-10, 2020, Behavioral Analysis of Single-Chain Glycolipids under Freezing and Drying Conditions, Shigezaburo Ogawa, Department of Materials and Life Sciences, Faculty of Science and Engineering, Seikei University) indicates that erythritol has a compressive strength of 2.0 MPa, a shear strength of 0.4 MPa, and a flexural strength of 1.0 MPa, while raffinose has a compressive strength of 1.8 MPa, a shear strength of 0.3 MPa, and a flexural strength of 0.9 MPa. This suggests that raffinose crystals are slightly softer than erythritol crystals. Figure 1 The observation photos shown indicate that raffinose can inhibit scratches on the tooth surface and crown surface.

[0039] The following describes the survey results regarding the tooth whitening effect produced by the tooth surface cleaning method of the present invention.

[0040] The teeth whitening effect test was conducted using dental spray powder mixed with raffinose (98.0%), silica (Aerosil R972, manufactured by EVONIK Co., Ltd. / 1.0%), and titanium dioxide (manufactured by Sakai Chemical Industry Co., Ltd. / 1.0%).

[0041] Two extracted teeth were used in the test. A commercially available tooth cleaner (Handy Jet, manufactured by Morita Co., Ltd.) was used at a pressure of 2.0 MPa and a spray time of 30 seconds to spray dental powder onto the surface of the extracted teeth. The cleaned tooth surface was then visually observed using a VITA Classical shade chart to confirm its lightness. The tooth whitening effect was then assessed by comparing the lightness of the tooth surface before cleaning with that of the extracted teeth before cleaning, using the same visually confirmed shade chart. Furthermore, a second tooth cleaning treatment was performed under the same conditions after the first treatment, and the lightness of the tooth surface after this second treatment was visually confirmed and compared with that of the tooth surface before cleaning. Tables 1 and 2 show the results of the tooth whitening effect test.

[0042] [Table 1]

[0043] Tooth extraction 1:

[0044] Color sample A3.5 C2 C1 Brightness variation － 4 stages 6 stages

[0045] [Table 2]

[0046] Tooth extraction 2:

[0047] Color sample C2 D2 B2 Brightness variation － Phase 3 4 stages

[0048] The symbols in the "Color Sample" column of Tables 1 and 2 represent the 16 levels of lightness in the VITA Classical Shade Chart (tooth color samples). Specifically, they correspond to the symbols for the 16 levels of tooth color samples: B1 / A1 / B2 / D2 / A2 / C1 / C2 / D3 / A3 / D4 / B3 / A3.5 / B4 / C3 / A4 / C4 (A series: reddish-brown, B series: reddish-yellow, C series: gray, D series: reddish-gray). The lightness is higher on the B1 side and decreases as it gets closer to the C4 side.

[0049] As shown in Tables 1 and 2, in both extracted teeth, the brightness of the tooth surface changed towards a brighter direction after the first cleaning treatment. Furthermore, in both extracted teeth, after the second cleaning treatment, it was confirmed that the brightness of the tooth surface changed further towards a brighter direction than after the first cleaning treatment.

[0050] Furthermore, the results of additional tests conducted on the tooth whitening effect produced by the tooth surface cleaning method of the present invention are described below. This additional tooth whitening effect test was conducted using a dental spray powder composed of raffinose (99.0%) and silica (Aerosil R972EVONIK, 1.0%). The commercially available tooth surface cleaners used and the test conditions were the same as those described in Tables 1 and 2 above, but the lightness of the tooth surface was measured using an automatic colorimeter (“VITA Easyshade V”, manufactured by VITA). The test results for two extracted teeth are shown in Tables 3 and 4.

[0051] [Table 3]

[0052] Tooth extraction 3:

[0053] Color sample A3.5 A3 A2 Brightness variation － Phase 3 7 stages

[0054] [Table 4]

[0055] Tooth extraction 4:

[0056] Color sample C4 A3.5 A3 Brightness variation － 4 stages 7 stages

[0057] The color sample results in Tables 3 and 4 are the lightness values ​​measured by an automatic colorimeter.

[0058] In this additional tooth whitening effect test, unlike the results in Tables 1 and 2, although a dental spray powder without titanium dioxide was used, it was found that for both extracted teeth, the surface brightness changed towards a brighter direction after the first cleaning treatment. Furthermore, it was confirmed that after the second cleaning treatment, the surface brightness changed further towards a brighter direction than after the first cleaning treatment.

[0059] Next, the situation regarding dental spray powder combining raffinose and bioactive glass will be explained. First, the results of the investigation on the cleaning power of dental spray powder containing bioactive glass will be explained. The dental spray powder referred to here is a mixture of 70% by weight raffinose (product name: raffinose FP, manufactured by Nippon Beet Sugar Co., Ltd., 99.0% by weight mixed with 1.0% by weight silica (R972)) and 30% by weight bioactive glass (trade name: Sylk, manufactured by Defotex Research Co., Ltd., 99.0% by weight mixed with 1.0% by weight silica (R972)). As a control group, dental spray powder consisting of 100% by weight bioactive glass (45S5) was also used. In addition, as the cleaning target, a copper substrate (a 10-yen coin with copper oxide formed on its surface) was used, and its surface was coated with black with an oil-based marker.

[0060] Two types of dental spray powder were used to clean the surface of the copper substrate. The spraying device was a commercially available dental spray cutter (product name "Aquacare", manufactured by Medivance Instruments, UK), with the handle inner diameter set to 0.8 mm, the spray pressure set to 2.0 MPa, and the spray distance set to 10 mm. The water volume was set to the medium level indicated on the spraying device's scale.

[0061] Figure 2 and Figure 3 The images show observations of the copper substrate surface after cleaning. Figure 2 For the case of mixing 70 wt% raffinose with 30 wt% bioactive glass in a dental spray powder, Figure 3 This refers to the case of dental spray powder containing 100% by weight of bioactive glass.

[0062] like Figure 2As shown, in the case of dental spray powder composed of 70% raffinose and 30% bioactive glass, the oily marker marks on the surface were almost completely removed. In contrast, in the case of dental spray powder composed of 100% bioactive glass, although the oily marker marks were removed, areas appeared where even copper oxide on the copper surface was removed. Figure 3 (The white part inside a 10-yen coin). Since bioactive glass has a hardness of approximately 400 Hv (Vickers hardness), it is known that using it alone as a dental spray powder can easily scratch tooth surfaces, exposed root surfaces, and crowns. However, it was discovered that when raffinose is combined with bioactive glass, the raffinose crystals bind to the surface of the bioactive glass, acting as a buffer during spray cleaning. This prevents scratches on tooth surfaces, exposed root surfaces, and crowns, while effectively removing biofilm and stains adhering to the tooth surface.

[0063] Finally, the results of the restaining assessment after tooth cleaning are presented. The dental spray powder used here was a mixture of 70% by weight raffinose (product name: raffinose FP, manufactured by Nippon Beetroot Sugar Co., Ltd., a mixture of 99.0% by weight and 1.0% by weight silica (R972)) and 30% by weight bioactive glass (trade name: Sylk, manufactured by Defotex Research Co., Ltd., a mixture of 99.0% by weight bioactive glass (45S5) and 1.0% by weight silica (R972)). As a control group, dental spray powder of 100% by weight (content ≥98%) was also used. Furthermore, the tooth surface cleaning subjects for the restaining assessment were the stained areas of the lower anterior teeth (4 teeth) from the same person's oral cavity. The tooth surface cleaning conditions were as follows: using a commercially available tooth surface cleaner (product name: Handy Jet, manufactured by Morita Co., Ltd.), dental spray powder was sprayed onto four stained lower anterior teeth at a pressure of 2.0 MPa and a spray time of 30 seconds to remove the stain. Reattachment assessment was performed by observing the four lower anterior teeth three months after the tooth surface cleaning.

[0064] Figure 4 and Figure 5 This image shows an intraoral observation three months after tooth cleaning. Figure 4 This refers to the case of a dental spray powder prepared by mixing 70% by weight raffinose and 30% by weight bioactive glass. Figure 5 This refers to the case of 100% by weight calcium carbonate dental spray powder.

[0065] like Figure 4As shown, for a dental spray powder composed of 70% by weight raffinose and 30% by weight bioactive glass, almost no restaining was observed on the tooth surfaces (4 lower anterior teeth) after 3 months. On the other hand, for a dental spray powder containing 100% by weight calcium carbonate, significant restaining was observed on the tooth surfaces (4 lower anterior teeth) after 3 months. Based on these restaining evaluation results, it was found that the lamellar liquid crystal structure formed by raffinose adhering to the tooth surface or periodontal tissues can enhance the barrier effect of the tooth surface epithelium, thereby effectively inhibiting restaining.

Claims

1. A method for cleaning tooth surfaces, comprising spraying dental aerosol powder onto the supragingival and / or subgingival surfaces of teeth for cleaning, wherein, Use dental spray powder containing raffinose.

2. The tooth surface cleaning method according to claim 1, wherein, The aforementioned dental spray powder contains at least one of silicon or titanium, or bioactive glass.

3. The tooth surface cleaning method according to claim 1 or 2, wherein, The median particle size of the aforementioned raffinose is 10 μm to 100 μm.

4. The tooth surface cleaning method according to any one of claims 1 to 3, wherein, After cleaning the tooth surface with dental spray powder, the cleaned tooth surface is then irradiated with a laser.

Images